Abcc8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcc8
Entrez Gene ID	25559
Full Name	ATP binding cassette subfamily C member 8
Synonyms	Sur,Sur1
General protein information	Preferred Names ATP binding cassette subfamily C member 8 Names ATP-binding cassette sub-family C member 8 ATP-binding cassette transporter sub-family C member 8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 sulfonylurea receptor 1 sulphonylurea receptor 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22
Summary	binds sulfonylurea; subunit of the ATP-sensitive potassium channel K(ATP), which is composed of Sur1 and the inwardly rectifying K(+) channel subunit, Kir6.2 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008759320.2	XP_008757542.1	ATP-binding cassette sub-family C member 8 isoform X1
XM_008759321.2	XP_008757543.1	ATP-binding cassette sub-family C member 8 isoform X2
NM_013039.2	NP_037171.2	ATP-binding cassette sub-family C member 8

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Abcc8	NP_035640.2
Gallus gallus (chicken)	ABCC8	XP_421005.2
Pan troglodytes (chimpanzee)	ABCC8	XP_508310.4
Macaca mulatta (Rhesus monkey)	ABCC8	XP_001088694.1
Canis lupus familiaris (dog)	ABCC8	XP_005633781.1
Bos taurus (cattle)	ABCC8	NP_001192539.1
Rattus norvegicus (Norway rat)	Abcc8	NP_037171.2
Danio rerio (zebrafish)	abcc8	NP_001166118.2
Homo sapiens (human)	ABCC8	NP_001274103.1

Gene Ontology
Bibliography

Related articles in PubMed

Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.
Cooper PE, McClenaghan C, Chen X, Stary-Weinzinger A, Nichols CG
The Journal of biological chemistry292(42)17387-17398(2017 10)

Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
Martin GM, Yoshioka C, Rex EA, Fay JF, Xie Q, Whorton MR, Chen JZ, Shyng SL
eLife6(2017 01)

SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.
Nicholson JD, Guo Y, Bernstein SL
PloS one11(8)e0148855(2016)

Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts.
Mehta RI, Tosun C, Ivanova S, Tsymbalyuk N, Famakin BM, Kwon MS, Castellani RJ, Gerzanich V, Simard JM
Journal of neuropathology and experimental neurology74(8)835-49(2015 Aug)

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity.
Fatehi M, Carter CR, Youssef N, Hunter BE, Holt A, Light PE
Bioscience reports35(4)(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Abcc8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcc8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13108	NM_013039.2 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
ORa43147	XM_008759320.2 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
ORa43148	XM_008759321.2 Latest version!	Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcc8 ( NM_013039.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037171.2 Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), mRNA.

Price & Availability↑

CloneID	ORa13108
Clone ID Related Accession (Same CDS sequence)	NM_013039.2
Accession Version	NM_013039.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Rattus norvegicus(Norway rat)
Product	ATP-binding cassette sub-family C member 8
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X97279.1. On May 30, 2007 this sequence version replaced NM_013039.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X97279.1, AB052294.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCTTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGC 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAATGTGG TGCCACATGT CTTTCTGCTC 
TTCATCACCT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTGCACATT 
CACCACAGCA CCTGGCTCCA TTTCCCGGGG CACAACCTGC GCTGGATCCT GACCTTCATA 
CTGCTCTTCG TCCTCGTGTG TGAGATCGCT GAGGGTATCC TGTCTGACGG GGTGACAGAA 
TCCCGCCACC TCCACTTATA CATGCCAGCT GGGATGGCAT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ACCATAACAT TGAGACCTCT AACTTTCCCA AGCTGCTGAT TGCTCTGCTC 
ATCTACTGGA CCCTGGCCTT CATCACGAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATTGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TTGTGGAGGT CAATGTCATC CGGGTGAGGA GATACGTCTT CTTCAAGACA 
CCAAGGGAAG TAAAGCCCCC CGAGGACCTA CAGGACCTGG GTGTGCGCTT TCTGCAGCCC 
TTCGTTAACC TGCTATCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCT 
CACAAGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATTGCCAT GAGAGCCCTC 
ACCAACTACC AGCGACTCTG CTTGGCCTTC GATGCCCAGG CGCGGAAGGA CACACAGAGC 
CAGCAGGGTG CCCGGGCCAT CTGGAGGGCT CTCTGTCATG CCTTTGGGAG ACGGCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCCGAC CTCCTGGGCT TTGCTGGGCC ACTCTGCATC 
TTCGGGATCG TGGACCACCT CGGGAAGGAG AACCACGTCT TCCAGCCCAA GACACAGTTT 
CTTGGAGTTT ACTTTGTCTC ATCCCAAGAG TTCCTCGGCA ATGCCTATGT CTTGGCTGTT 
CTTCTGTTCC TTGCCCTCCT GCTGCAAAGG ACCTTTCTAC AAGCCTCGTA CTACGTTGCC 
ATTGAAACTG GGATCAACCT GAGAGGAGCA ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCCATGGGG GAAATGACTG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACCAACCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCGGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGCGCC 
TTGATTGGAG CGGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTGTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AGAGGCTGAA GCAGACCAAT 
GAGATGCTCC GGGGCATCAA GTTGCTCAAG CTCTATGCGT GGGAGAACAT CTTCTGCTCC 
AGGGTGGAGA AGACACGCAG GAAGGAAATG ACCAGCCTCA GGGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATCGCTG CTGTCCTCAT CACCTTCGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCGGAC TTCTCGCCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACT 
GTCAAGGCCC TGGTGAGCGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCCGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTCGTAAA CCGCAAGCGC CCAGCCCGAG AAGAAGTCCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC TCCCAGCACG GATGGAGACG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGTCA GCTGACCATG ATCGTGGGGC AGGTGGGCTG TGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAAGGTCT CTGGAGCTGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGCAACC CAGAGCGGGA GACAGCGGCC 
GATTCGGATG CCAGGAGCAG AGGCCCTGTG GCCTACGCAT CTCAGAAACC ATGGCTGCTA 
AATGCCACTG TGGAGGAGAA CATCACCTTC GAGAGTCCCT TCAATAAGCA ACGGTACAAG 
ATGGTCATCG AAGCCTGCTC CCTGCAGCCA GACATAGACA TCCTGCCCCA TGGAGACCAG 
ACTCAGATTG GGGAACGGGG CATCAACTTG TCTGGTGGTC AGCGTCAGCG AATCAGTGTA 
GCCCGAGCCC TCTACCAGCA CACCAATGTT GTCTTTTTGG ATGACCCTTT CTCGGCTCTG 
GATGTCCATC TGAGTGACCA CCTAATGCAG GCTGGCATCC TCGAGCTGCT CCGGGATGAC 
AAGAGGACAG TGGTCTTGGT GACCCACAAG CTACAGTACC TGCCTCATGC TGACTGGATC 
ATTGCTATGA AGGATGGCAC CATTCAGAGG GAGGGGACAC TCAAGGACTT CCAGAGGTCT 
GAGTGCCAGC TCTTTGAGCA TTGGAAGACC CTCATGAACC GGCAGGACCA AGAGCTGGAG 
AAGGAGACAG TCATGGAGAG AAAAGCCCCA GAGCCATCTC AGGGCCTGCC CCGTGCCATG 
TCCTCAAGAG ATGGCCTTCT GCTGGATGAG GATGAGGAGG AAGAGGAGGC AGCCGAGAGC 
GAGGAAGATG ACAACTTATC CTCTGTGCTG CATCAGCGAG CCAAGATCCC ATGGCGAGCC 
TGCACCAAGT ATTTGTCCTC TGCTGGCATC CTGCTCCTGT CCCTGCTTGT CTTCTCCCAG 
CTGCTCAAGC ACATGGTCTT GGTGGCCATT GACTACTGGC TGGCCAAGTG GACGGACAGT 
GCCCTGGTCC TGAGCCCCGC CGCCAGGAAC TGCTCCCTCA GCCAGGAATG TGCCCTGGAC 
CAATCTGTCT ATGCCATGGT ATTCACCGTG CTCTGCAGCC TGGGTATCGC GCTGTGCCTT 
GTCACCTCTG TCACTGTGGA GTGGACGGGA CTGAAGGTGG CCAAGAGGCT GCATCGCAGC 
CTGCTCAACC GTATCATCCT GGCTCCCATG AGGTTCTTTG AGACCACGCC CCTGGGGAGT 
ATCCTGAACA GATTTTCATC TGACTGTAAC ACCATTGACC AGCATATCCC GTCCACGCTG 
GAGTGCCTGA GCAGATCCAC CTTACTCTGT GTCTCCGCCC TGGCTGTCAT CTCCTACGTC 
ACGCCTGTGT TCCTAGTGGC CCTCTTACCC CTCGCCGTCG TGTGCTACTT CATCCAGAAG 
TACTTCCGAG TGGCGTCCAG GGACCTGCAG CAGCTGGACG ACACAACACA GCTCCCTCTG 
CTCTCACACT TTGCTGAAAC TGTGGAAGGA CTCACCACCA TCCGTGCCTT CAGGTACGAG 
GCCCGGTTCC AGCAGAAGCT CCTAGAGTAC ACCGACTCCA ACAACATTGC CTCTCTCTTC 
CTCACAGCAG CCAACAGGTG GCTGGAAGTC CGCATGGAGT ACATCGGAGC ATGCGTGGTA 
CTCATCGCCG CTGCCACCTC CATCTCCAAC TCCCTACACA GGGAGCTCTC AGCCGGCCTA 
GTAGGCCTGG GCCTCACCTA TGCCTTGATG GTCTCCAACT ACCTCAACTG GATGGTGAGG 
AACCTGGCAG ACATGGAGAT CCAACTGGGA GCTGTGAAGC GTATCCACAC ACTCCTGAAA 
ACTGAGGCAG AGAGCTATGA GGGGCTCCTG GCACCATCGC TGATCCCCAA GAACTGGCCA 
GACCAAGGGA AGATCCAAAT TCAAAACCTG AGTGTACGCT ATGACAGCTC CCTGAAGCCC 
GTGCTGAAGC ACGTCAACGC CCTCATCTCC CCAGGACAGA AGATTGGGAT CTGCGGCCGC 
ACAGGCAGTG GAAAATCCTC CTTCTCTCTC GCCTTTTTCC GAATGGTGGA TATGTTTGAA 
GGGCGTATCA TCATCGATGG CATTGACATC GCCAAGCTGC CGCTGCACAC GCTCCGCTCA 
CGCCTGTCTA TCATCCTACA GGACCCTGTT CTCTTCAGTG GTACCATCAG ATTCAACCTG 
GACCCAGAGA AGAAATGCTC AGACAGCACG CTGTGGGAGG CTCTGGAGAT CGCTCAGCTG 
AAGCTGGTGG TGAAGGCCCT GCCAGGAGGC CTGGATGCCA TCATCACGGA AGGAGGGGAG 
AATTTTAGCC AGGGCCAGAG GCAGCTGTTC TGCCTGGCCC GGGCCTTTGT GAGGAAGACC 
AGCATCTTCA TCATGGATGA AGCAACTGCC TCCATCGACA TGGCTACGGA AAATATCCTC 
CAGAAGGTGG TGATGACAGC CTTCGCAGAC CGCACCGTGG TCACCATCGC GCACCGCGTG 
CACACCATCC TGAGTGCAGA CCTAGTGATG GTCCTGAAGA GGGGCGCGAT CCTGGAGTTC 
GACAAGCCGG AAAAGCTTCT CAGCCAGAAG GACAGCGTCT TTGCCTCCTT TGTCCGCGCG 
GACAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037171.2
CDS	1..4749
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYVFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCLAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEKTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSTDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK

Target ORF information:

RefSeq Version	NM_013039.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013039.2

ORF Insert Sequence:

ATGCCTTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGC 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAATGTGG TGCCACATGT CTTTCTGCTC 
TTCATCACCT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTGCACATT 
CACCACAGCA CCTGGCTCCA TTTCCCGGGG CACAACCTGC GCTGGATCCT GACCTTCATA 
CTGCTCTTCG TCCTCGTGTG TGAGATCGCT GAGGGTATCC TGTCTGACGG GGTGACAGAA 
TCCCGCCACC TCCACTTATA CATGCCAGCT GGGATGGCAT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ACCATAACAT TGAGACCTCT AACTTTCCCA AGCTGCTGAT TGCTCTGCTC 
ATCTACTGGA CCCTGGCCTT CATCACGAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATTGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TTGTGGAGGT CAATGTCATC CGGGTGAGGA GATACGTCTT CTTCAAGACA 
CCAAGGGAAG TAAAGCCCCC CGAGGACCTA CAGGACCTGG GTGTGCGCTT TCTGCAGCCC 
TTCGTTAACC TGCTATCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCT 
CACAAGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATTGCCAT GAGAGCCCTC 
ACCAACTACC AGCGACTCTG CTTGGCCTTC GATGCCCAGG CGCGGAAGGA CACACAGAGC 
CAGCAGGGTG CCCGGGCCAT CTGGAGGGCT CTCTGTCATG CCTTTGGGAG ACGGCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCCGAC CTCCTGGGCT TTGCTGGGCC ACTCTGCATC 
TTCGGGATCG TGGACCACCT CGGGAAGGAG AACCACGTCT TCCAGCCCAA GACACAGTTT 
CTTGGAGTTT ACTTTGTCTC ATCCCAAGAG TTCCTCGGCA ATGCCTATGT CTTGGCTGTT 
CTTCTGTTCC TTGCCCTCCT GCTGCAAAGG ACCTTTCTAC AAGCCTCGTA CTACGTTGCC 
ATTGAAACTG GGATCAACCT GAGAGGAGCA ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCCATGGGG GAAATGACTG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACCAACCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCGGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGCGCC 
TTGATTGGAG CGGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTGTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AGAGGCTGAA GCAGACCAAT 
GAGATGCTCC GGGGCATCAA GTTGCTCAAG CTCTATGCGT GGGAGAACAT CTTCTGCTCC 
AGGGTGGAGA AGACACGCAG GAAGGAAATG ACCAGCCTCA GGGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATCGCTG CTGTCCTCAT CACCTTCGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCGGAC TTCTCGCCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACT 
GTCAAGGCCC TGGTGAGCGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCCGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTCGTAAA CCGCAAGCGC CCAGCCCGAG AAGAAGTCCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC TCCCAGCACG GATGGAGACG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGTCA GCTGACCATG ATCGTGGGGC AGGTGGGCTG TGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAAGGTCT CTGGAGCTGT CTTCTGGAAC 
AGCAGCCTTC CAGACAGCGA GGGAGAAGAC CCCAGCAACC CAGAGCGGGA GACAGCGGCC 
GATTCGGATG CCAGGAGCAG AGGCCCTGTG GCCTACGCAT CTCAGAAACC ATGGCTGCTA 
AATGCCACTG TGGAGGAGAA CATCACCTTC GAGAGTCCCT TCAATAAGCA ACGGTACAAG 
ATGGTCATCG AAGCCTGCTC CCTGCAGCCA GACATAGACA TCCTGCCCCA TGGAGACCAG 
ACTCAGATTG GGGAACGGGG CATCAACTTG TCTGGTGGTC AGCGTCAGCG AATCAGTGTA 
GCCCGAGCCC TCTACCAGCA CACCAATGTT GTCTTTTTGG ATGACCCTTT CTCGGCTCTG 
GATGTCCATC TGAGTGACCA CCTAATGCAG GCTGGCATCC TCGAGCTGCT CCGGGATGAC 
AAGAGGACAG TGGTCTTGGT GACCCACAAG CTACAGTACC TGCCTCATGC TGACTGGATC 
ATTGCTATGA AGGATGGCAC CATTCAGAGG GAGGGGACAC TCAAGGACTT CCAGAGGTCT 
GAGTGCCAGC TCTTTGAGCA TTGGAAGACC CTCATGAACC GGCAGGACCA AGAGCTGGAG 
AAGGAGACAG TCATGGAGAG AAAAGCCCCA GAGCCATCTC AGGGCCTGCC CCGTGCCATG 
TCCTCAAGAG ATGGCCTTCT GCTGGATGAG GATGAGGAGG AAGAGGAGGC AGCCGAGAGC 
GAGGAAGATG ACAACTTATC CTCTGTGCTG CATCAGCGAG CCAAGATCCC ATGGCGAGCC 
TGCACCAAGT ATTTGTCCTC TGCTGGCATC CTGCTCCTGT CCCTGCTTGT CTTCTCCCAG 
CTGCTCAAGC ACATGGTCTT GGTGGCCATT GACTACTGGC TGGCCAAGTG GACGGACAGT 
GCCCTGGTCC TGAGCCCCGC CGCCAGGAAC TGCTCCCTCA GCCAGGAATG TGCCCTGGAC 
CAATCTGTCT ATGCCATGGT ATTCACCGTG CTCTGCAGCC TGGGTATCGC GCTGTGCCTT 
GTCACCTCTG TCACTGTGGA GTGGACGGGA CTGAAGGTGG CCAAGAGGCT GCATCGCAGC 
CTGCTCAACC GTATCATCCT GGCTCCCATG AGGTTCTTTG AGACCACGCC CCTGGGGAGT 
ATCCTGAACA GATTTTCATC TGACTGTAAC ACCATTGACC AGCATATCCC GTCCACGCTG 
GAGTGCCTGA GCAGATCCAC CTTACTCTGT GTCTCCGCCC TGGCTGTCAT CTCCTACGTC 
ACGCCTGTGT TCCTAGTGGC CCTCTTACCC CTCGCCGTCG TGTGCTACTT CATCCAGAAG 
TACTTCCGAG TGGCGTCCAG GGACCTGCAG CAGCTGGACG ACACAACACA GCTCCCTCTG 
CTCTCACACT TTGCTGAAAC TGTGGAAGGA CTCACCACCA TCCGTGCCTT CAGGTACGAG 
GCCCGGTTCC AGCAGAAGCT CCTAGAGTAC ACCGACTCCA ACAACATTGC CTCTCTCTTC 
CTCACAGCAG CCAACAGGTG GCTGGAAGTC CGCATGGAGT ACATCGGAGC ATGCGTGGTA 
CTCATCGCCG CTGCCACCTC CATCTCCAAC TCCCTACACA GGGAGCTCTC AGCCGGCCTA 
GTAGGCCTGG GCCTCACCTA TGCCTTGATG GTCTCCAACT ACCTCAACTG GATGGTGAGG 
AACCTGGCAG ACATGGAGAT CCAACTGGGA GCTGTGAAGC GTATCCACAC ACTCCTGAAA 
ACTGAGGCAG AGAGCTATGA GGGGCTCCTG GCACCATCGC TGATCCCCAA GAACTGGCCA 
GACCAAGGGA AGATCCAAAT TCAAAACCTG AGTGTACGCT ATGACAGCTC CCTGAAGCCC 
GTGCTGAAGC ACGTCAACGC CCTCATCTCC CCAGGACAGA AGATTGGGAT CTGCGGCCGC 
ACAGGCAGTG GAAAATCCTC CTTCTCTCTC GCCTTTTTCC GAATGGTGGA TATGTTTGAA 
GGGCGTATCA TCATCGATGG CATTGACATC GCCAAGCTGC CGCTGCACAC GCTCCGCTCA 
CGCCTGTCTA TCATCCTACA GGACCCTGTT CTCTTCAGTG GTACCATCAG ATTCAACCTG 
GACCCAGAGA AGAAATGCTC AGACAGCACG CTGTGGGAGG CTCTGGAGAT CGCTCAGCTG 
AAGCTGGTGG TGAAGGCCCT GCCAGGAGGC CTGGATGCCA TCATCACGGA AGGAGGGGAG 
AATTTTAGCC AGGGCCAGAG GCAGCTGTTC TGCCTGGCCC GGGCCTTTGT GAGGAAGACC 
AGCATCTTCA TCATGGATGA AGCAACTGCC TCCATCGACA TGGCTACGGA AAATATCCTC 
CAGAAGGTGG TGATGACAGC CTTCGCAGAC CGCACCGTGG TCACCATCGC GCACCGCGTG 
CACACCATCC TGAGTGCAGA CCTAGTGATG GTCCTGAAGA GGGGCGCGAT CCTGGAGTTC 
GACAAGCCGG AAAAGCTTCT CAGCCAGAAG GACAGCGTCT TTGCCTCCTT TGTCCGCGCG 
GACAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc8 ( XM_008759320.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757542.1 Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43147
Clone ID Related Accession (Same CDS sequence)	XM_008759320.2
Accession Version	XM_008759320.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4746bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	ATP-binding cassette sub-family C member 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759320.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGC 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAATGTGG TGCCACATGT CTTTCTGCTC 
TTCATCACCT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTGCACATT 
CACCACAGCA CCTGGCTCCA TTTCCCGGGG CACAACCTGC GCTGGATCCT GACCTTCATA 
CTGCTCTTCG TCCTCGTGTG TGAGATCGCT GAGGGTATCC TGTCTGACGG GGTGACAGAA 
TCCCGCCACC TCCACTTATA CATGCCAGCT GGGATGGCAT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ACCATAACAT TGAGACCTCT AACTTTCCCA AGCTGCTGAT TGCTCTGCTC 
ATCTACTGGA CCCTGGCCTT CATCACGAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATTGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TTGTGGAGGT CAATGTCATC CGGGTGAGGA GATACGTCTT CTTCAAGACA 
CCAAGGGAAG TAAAGCCCCC CGAGGACCTA CAGGACCTGG GTGTGCGCTT TCTGCAGCCC 
TTCGTTAACC TGCTATCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCT 
CACAAGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATTGCCAT GAGAGCCCTC 
ACCAACTACC AGCGACTCTG CTTGGCCTTC GATGCCCAGG CGCGGAAGGA CACACAGAGC 
CAGCAGGGTG CCCGGGCCAT CTGGAGGGCT CTCTGTCATG CCTTTGGGAG ACGGCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCCGAC CTCCTGGGCT TTGCTGGGCC ACTCTGCATC 
TTCGGGATCG TGGACCACCT CGGGAAGGAG AACCACGTCT TCCAGCCCAA GACACAGTTT 
CTTGGAGTTT ACTTTGTCTC ATCCCAAGAG TTCCTCGGCA ATGCCTATGT CTTGGCTGTT 
CTTCTGTTCC TTGCCCTCCT GCTGCAAAGG ACCTTTCTAC AAGCCTCGTA CTACGTTGCC 
ATTGAAACTG GGATCAACCT GAGAGGAGCA ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCCATGGGG GAAATGACTG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACCAACCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCGGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGCGCC 
TTGATTGGAG CGGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTGTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AGAGGCTGAA GCAGACCAAT 
GAGATGCTCC GGGGCATCAA GTTGCTCAAG CTCTATGCGT GGGAGAACAT CTTCTGCTCC 
AGGGTGGAGA AGACACGCAG GAAGGAAATG ACCAGCCTCA GGGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATCGCTG CTGTCCTCAT CACCTTCGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCGGAC TTCTCGCCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACT 
GTCAAGGCCC TGGTGAGCGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCCGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTCGTAAA CCGCAAGCGC CCAGCCCGAG AAGAAGTCCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC TCCCAGCACG GATGGAGACG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGTCA GCTGACCATG ATCGTGGGGC AGGTGGGCTG TGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAAGGTCT CTGGAGCTGT CTTCTGGAAC 
AGCCTTCCAG ACAGCGAGGG AGAAGACCCC AGCAACCCAG AGCGGGAGAC AGCGGCCGAT 
TCGGATGCCA GGAGCAGAGG CCCTGTGGCC TACGCATCTC AGAAACCATG GCTGCTAAAT 
GCCACTGTGG AGGAGAACAT CACCTTCGAG AGTCCCTTCA ATAAGCAACG GTACAAGATG 
GTCATCGAAG CCTGCTCCCT GCAGCCAGAC ATAGACATCC TGCCCCATGG AGACCAGACT 
CAGATTGGGG AACGGGGCAT CAACTTGTCT GGTGGTCAGC GTCAGCGAAT CAGTGTAGCC 
CGAGCCCTCT ACCAGCACAC CAATGTTGTC TTTTTGGATG ACCCTTTCTC GGCTCTGGAT 
GTCCATCTGA GTGACCACCT AATGCAGGCT GGCATCCTCG AGCTGCTCCG GGATGACAAG 
AGGACAGTGG TCTTGGTGAC CCACAAGCTA CAGTACCTGC CTCATGCTGA CTGGATCATT 
GCTATGAAGG ATGGCACCAT TCAGAGGGAG GGGACACTCA AGGACTTCCA GAGGTCTGAG 
TGCCAGCTCT TTGAGCATTG GAAGACCCTC ATGAACCGGC AGGACCAAGA GCTGGAGAAG 
GAGACAGTCA TGGAGAGAAA AGCCCCAGAG CCATCTCAGG GCCTGCCCCG TGCCATGTCC 
TCAAGAGATG GCCTTCTGCT GGATGAGGAT GAGGAGGAAG AGGAGGCAGC CGAGAGCGAG 
GAAGATGACA ACTTATCCTC TGTGCTGCAT CAGCGAGCCA AGATCCCATG GCGAGCCTGC 
ACCAAGTATT TGTCCTCTGC TGGCATCCTG CTCCTGTCCC TGCTTGTCTT CTCCCAGCTG 
CTCAAGCACA TGGTCTTGGT GGCCATTGAC TACTGGCTGG CCAAGTGGAC GGACAGTGCC 
CTGGTCCTGA GCCCCGCCGC CAGGAACTGC TCCCTCAGCC AGGAATGTGC CCTGGACCAA 
TCTGTCTATG CCATGGTATT CACCGTGCTC TGCAGCCTGG GTATCGCGCT GTGCCTTGTC 
ACCTCTGTCA CTGTGGAGTG GACGGGACTG AAGGTGGCCA AGAGGCTGCA TCGCAGCCTG 
CTCAACCGTA TCATCCTGGC TCCCATGAGG TTCTTTGAGA CCACGCCCCT GGGGAGTATC 
CTGAACAGAT TTTCATCTGA CTGTAACACC ATTGACCAGC ATATCCCGTC CACGCTGGAG 
TGCCTGAGCA GATCCACCTT ACTCTGTGTC TCCGCCCTGG CTGTCATCTC CTACGTCACG 
CCTGTGTTCC TAGTGGCCCT CTTACCCCTC GCCGTCGTGT GCTACTTCAT CCAGAAGTAC 
TTCCGAGTGG CGTCCAGGGA CCTGCAGCAG CTGGACGACA CAACACAGCT CCCTCTGCTC 
TCACACTTTG CTGAAACTGT GGAAGGACTC ACCACCATCC GTGCCTTCAG GTACGAGGCC 
CGGTTCCAGC AGAAGCTCCT AGAGTACACC GACTCCAACA ACATTGCCTC TCTCTTCCTC 
ACAGCAGCCA ACAGGTGGCT GGAAGTCCGC ATGGAGTACA TCGGAGCATG CGTGGTACTC 
ATCGCCGCTG CCACCTCCAT CTCCAACTCC CTACACAGGG AGCTCTCAGC CGGCCTAGTA 
GGCCTGGGCC TCACCTATGC CTTGATGGTC TCCAACTACC TCAACTGGAT GGTGAGGAAC 
CTGGCAGACA TGGAGATCCA ACTGGGAGCT GTGAAGCGTA TCCACACACT CCTGAAAACT 
GAGGCAGAGA GCTATGAGGG GCTCCTGGCA CCATCGCTGA TCCCCAAGAA CTGGCCAGAC 
CAAGGGAAGA TCCAAATTCA AAACCTGAGT GTACGCTATG ACAGCTCCCT GAAGCCCGTG 
CTGAAGCACG TCAACGCCCT CATCTCCCCA GGACAGAAGA TTGGGATCTG CGGCCGCACA 
GGCAGTGGAA AATCCTCCTT CTCTCTCGCC TTTTTCCGAA TGGTGGATAT GTTTGAAGGG 
CGTATCATCA TCGATGGCAT TGACATCGCC AAGCTGCCGC TGCACACGCT CCGCTCACGC 
CTGTCTATCA TCCTACAGGA CCCTGTTCTC TTCAGTGGTA CCATCAGATT CAACCTGGAC 
CCAGAGAAGA AATGCTCAGA CAGCACGCTG TGGGAGGCTC TGGAGATCGC TCAGCTGAAG 
CTGGTGGTGA AGGCCCTGCC AGGAGGCCTG GATGCCATCA TCACGGAAGG AGGGGAGAAT 
TTTAGCCAGG GCCAGAGGCA GCTGTTCTGC CTGGCCCGGG CCTTTGTGAG GAAGACCAGC 
ATCTTCATCA TGGATGAAGC AACTGCCTCC ATCGACATGG CTACGGAAAA TATCCTCCAG 
AAGGTGGTGA TGACAGCCTT CGCAGACCGC ACCGTGGTCA CCATCGCGCA CCGCGTGCAC 
ACCATCCTGA GTGCAGACCT AGTGATGGTC CTGAAGAGGG GCGCGATCCT GGAGTTCGAC 
AAGCCGGAAA AGCTTCTCAG CCAGAAGGAC AGCGTCTTTG CCTCCTTTGT CCGCGCGGAC 
AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757542.1
CDS	1..4746
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYVFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCLAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEKTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSTDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK

Target ORF information:

RefSeq Version	XM_008759320.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759320.2

ORF Insert Sequence:

ATGCCTTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGC 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAATGTGG TGCCACATGT CTTTCTGCTC 
TTCATCACCT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTGCACATT 
CACCACAGCA CCTGGCTCCA TTTCCCGGGG CACAACCTGC GCTGGATCCT GACCTTCATA 
CTGCTCTTCG TCCTCGTGTG TGAGATCGCT GAGGGTATCC TGTCTGACGG GGTGACAGAA 
TCCCGCCACC TCCACTTATA CATGCCAGCT GGGATGGCAT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ACCATAACAT TGAGACCTCT AACTTTCCCA AGCTGCTGAT TGCTCTGCTC 
ATCTACTGGA CCCTGGCCTT CATCACGAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATTGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TTGTGGAGGT CAATGTCATC CGGGTGAGGA GATACGTCTT CTTCAAGACA 
CCAAGGGAAG TAAAGCCCCC CGAGGACCTA CAGGACCTGG GTGTGCGCTT TCTGCAGCCC 
TTCGTTAACC TGCTATCAAA GGGGACCTAC TGGTGGATGA ATGCCTTCAT CAAGACTGCT 
CACAAGAAGC CCATCGACCT GCGGGCCATC GGGAAGCTGC CCATTGCCAT GAGAGCCCTC 
ACCAACTACC AGCGACTCTG CTTGGCCTTC GATGCCCAGG CGCGGAAGGA CACACAGAGC 
CAGCAGGGTG CCCGGGCCAT CTGGAGGGCT CTCTGTCATG CCTTTGGGAG ACGGCTGGTC 
CTCAGCAGCA CATTCCGTAT CCTGGCCGAC CTCCTGGGCT TTGCTGGGCC ACTCTGCATC 
TTCGGGATCG TGGACCACCT CGGGAAGGAG AACCACGTCT TCCAGCCCAA GACACAGTTT 
CTTGGAGTTT ACTTTGTCTC ATCCCAAGAG TTCCTCGGCA ATGCCTATGT CTTGGCTGTT 
CTTCTGTTCC TTGCCCTCCT GCTGCAAAGG ACCTTTCTAC AAGCCTCGTA CTACGTTGCC 
ATTGAAACTG GGATCAACCT GAGAGGAGCA ATCCAGACCA AGATTTACAA TAAGATCATG 
CACTTGTCTA CTTCCAACCT GTCCATGGGG GAAATGACTG CTGGGCAGAT CTGCAACCTG 
GTGGCCATCG ACACCAACCA GCTCATGTGG TTTTTCTTCT TATGCCCAAA CCTCTGGGCT 
ATGCCGGTAC AGATCATTGT GGGCGTGATC CTCCTCTACT ACATCCTTGG GGTCAGCGCC 
TTGATTGGAG CGGCTGTCAT CATTCTGCTG GCTCCTGTAC AGTACTTTGT GGCCACCAAG 
CTGTCCCAGG CACAGCGGAG CACCCTGGAA TATTCCAATG AGAGGCTGAA GCAGACCAAT 
GAGATGCTCC GGGGCATCAA GTTGCTCAAG CTCTATGCGT GGGAGAACAT CTTCTGCTCC 
AGGGTGGAGA AGACACGCAG GAAGGAAATG ACCAGCCTCA GGGCCTTCGC TGTCTACACC 
TCCATCTCCA TCTTCATGAA CACAGCTATC CCCATCGCTG CTGTCCTCAT CACCTTCGTG 
GGCCACGTCA GCTTCTTCAA AGAGTCGGAC TTCTCGCCCT CGGTGGCCTT TGCCTCTCTC 
TCTCTCTTCC ACATCCTGGT CACACCGCTG TTCCTGCTGT CTAGTGTGGT TCGGTCCACT 
GTCAAGGCCC TGGTGAGCGT GCAAAAGCTG AGTGAGTTCC TGTCCAGTGC AGAGATCCGT 
GAGGAACAGT GTGCCCCCCG AGAGCCCGCA CCCCAAGGCC AAGCGGGCAA GTACCAGGCG 
GTGCCCCTCA AGGTCGTAAA CCGCAAGCGC CCAGCCCGAG AAGAAGTCCG GGACCTCTTG 
GGCCCACTGC AGAGGCTGAC TCCCAGCACG GATGGAGACG CTGACAACTT CTGTGTCCAG 
ATCATCGGAG GCTTCTTCAC CTGGACCCCT GATGGAATCC CCACCCTGTC CAACATCACC 
ATCCGTATCC CCCGAGGTCA GCTGACCATG ATCGTGGGGC AGGTGGGCTG TGGCAAGTCC 
TCGCTCCTTC TGGCCACCCT GGGGGAGATG CAGAAGGTCT CTGGAGCTGT CTTCTGGAAC 
AGCCTTCCAG ACAGCGAGGG AGAAGACCCC AGCAACCCAG AGCGGGAGAC AGCGGCCGAT 
TCGGATGCCA GGAGCAGAGG CCCTGTGGCC TACGCATCTC AGAAACCATG GCTGCTAAAT 
GCCACTGTGG AGGAGAACAT CACCTTCGAG AGTCCCTTCA ATAAGCAACG GTACAAGATG 
GTCATCGAAG CCTGCTCCCT GCAGCCAGAC ATAGACATCC TGCCCCATGG AGACCAGACT 
CAGATTGGGG AACGGGGCAT CAACTTGTCT GGTGGTCAGC GTCAGCGAAT CAGTGTAGCC 
CGAGCCCTCT ACCAGCACAC CAATGTTGTC TTTTTGGATG ACCCTTTCTC GGCTCTGGAT 
GTCCATCTGA GTGACCACCT AATGCAGGCT GGCATCCTCG AGCTGCTCCG GGATGACAAG 
AGGACAGTGG TCTTGGTGAC CCACAAGCTA CAGTACCTGC CTCATGCTGA CTGGATCATT 
GCTATGAAGG ATGGCACCAT TCAGAGGGAG GGGACACTCA AGGACTTCCA GAGGTCTGAG 
TGCCAGCTCT TTGAGCATTG GAAGACCCTC ATGAACCGGC AGGACCAAGA GCTGGAGAAG 
GAGACAGTCA TGGAGAGAAA AGCCCCAGAG CCATCTCAGG GCCTGCCCCG TGCCATGTCC 
TCAAGAGATG GCCTTCTGCT GGATGAGGAT GAGGAGGAAG AGGAGGCAGC CGAGAGCGAG 
GAAGATGACA ACTTATCCTC TGTGCTGCAT CAGCGAGCCA AGATCCCATG GCGAGCCTGC 
ACCAAGTATT TGTCCTCTGC TGGCATCCTG CTCCTGTCCC TGCTTGTCTT CTCCCAGCTG 
CTCAAGCACA TGGTCTTGGT GGCCATTGAC TACTGGCTGG CCAAGTGGAC GGACAGTGCC 
CTGGTCCTGA GCCCCGCCGC CAGGAACTGC TCCCTCAGCC AGGAATGTGC CCTGGACCAA 
TCTGTCTATG CCATGGTATT CACCGTGCTC TGCAGCCTGG GTATCGCGCT GTGCCTTGTC 
ACCTCTGTCA CTGTGGAGTG GACGGGACTG AAGGTGGCCA AGAGGCTGCA TCGCAGCCTG 
CTCAACCGTA TCATCCTGGC TCCCATGAGG TTCTTTGAGA CCACGCCCCT GGGGAGTATC 
CTGAACAGAT TTTCATCTGA CTGTAACACC ATTGACCAGC ATATCCCGTC CACGCTGGAG 
TGCCTGAGCA GATCCACCTT ACTCTGTGTC TCCGCCCTGG CTGTCATCTC CTACGTCACG 
CCTGTGTTCC TAGTGGCCCT CTTACCCCTC GCCGTCGTGT GCTACTTCAT CCAGAAGTAC 
TTCCGAGTGG CGTCCAGGGA CCTGCAGCAG CTGGACGACA CAACACAGCT CCCTCTGCTC 
TCACACTTTG CTGAAACTGT GGAAGGACTC ACCACCATCC GTGCCTTCAG GTACGAGGCC 
CGGTTCCAGC AGAAGCTCCT AGAGTACACC GACTCCAACA ACATTGCCTC TCTCTTCCTC 
ACAGCAGCCA ACAGGTGGCT GGAAGTCCGC ATGGAGTACA TCGGAGCATG CGTGGTACTC 
ATCGCCGCTG CCACCTCCAT CTCCAACTCC CTACACAGGG AGCTCTCAGC CGGCCTAGTA 
GGCCTGGGCC TCACCTATGC CTTGATGGTC TCCAACTACC TCAACTGGAT GGTGAGGAAC 
CTGGCAGACA TGGAGATCCA ACTGGGAGCT GTGAAGCGTA TCCACACACT CCTGAAAACT 
GAGGCAGAGA GCTATGAGGG GCTCCTGGCA CCATCGCTGA TCCCCAAGAA CTGGCCAGAC 
CAAGGGAAGA TCCAAATTCA AAACCTGAGT GTACGCTATG ACAGCTCCCT GAAGCCCGTG 
CTGAAGCACG TCAACGCCCT CATCTCCCCA GGACAGAAGA TTGGGATCTG CGGCCGCACA 
GGCAGTGGAA AATCCTCCTT CTCTCTCGCC TTTTTCCGAA TGGTGGATAT GTTTGAAGGG 
CGTATCATCA TCGATGGCAT TGACATCGCC AAGCTGCCGC TGCACACGCT CCGCTCACGC 
CTGTCTATCA TCCTACAGGA CCCTGTTCTC TTCAGTGGTA CCATCAGATT CAACCTGGAC 
CCAGAGAAGA AATGCTCAGA CAGCACGCTG TGGGAGGCTC TGGAGATCGC TCAGCTGAAG 
CTGGTGGTGA AGGCCCTGCC AGGAGGCCTG GATGCCATCA TCACGGAAGG AGGGGAGAAT 
TTTAGCCAGG GCCAGAGGCA GCTGTTCTGC CTGGCCCGGG CCTTTGTGAG GAAGACCAGC 
ATCTTCATCA TGGATGAAGC AACTGCCTCC ATCGACATGG CTACGGAAAA TATCCTCCAG 
AAGGTGGTGA TGACAGCCTT CGCAGACCGC ACCGTGGTCA CCATCGCGCA CCGCGTGCAC 
ACCATCCTGA GTGCAGACCT AGTGATGGTC CTGAAGAGGG GCGCGATCCT GGAGTTCGAC 
AAGCCGGAAA AGCTTCTCAG CCAGAAGGAC AGCGTCTTTG CCTCCTTTGT CCGCGCGGAC 
AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcc8 ( XM_008759321.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757543.1 Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), transcript variant X2, mRNA.

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CloneID	ORa43148
Clone ID Related Accession (Same CDS sequence)	XM_008759321.2
Accession Version	XM_008759321.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	ATP-binding cassette sub-family C member 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759321.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGC 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAATGTGG TGCCACATGT CTTTCTGCTC 
TTCATCACCT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTGCACATT 
CACCACAGCA CCTGGCTCCA TTTCCCGGGG CACAACCTGC GCTGGATCCT GACCTTCATA 
CTGCTCTTCG TCCTCGTGTG TGAGATCGCT GAGGGTATCC TGTCTGACGG GGTGACAGAA 
TCCCGCCACC TCCACTTATA CATGCCAGCT GGGATGGCAT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ACCATAACAT TGAGACCTCT AACTTTCCCA AGCTGCTGAT TGCTCTGCTC 
ATCTACTGGA CCCTGGCCTT CATCACGAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATTGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TTGTGGAGGT CAATGTCATC CGGGTGAGGC CCTTCGTTAA CCTGCTATCA 
AAGGGGACCT ACTGGTGGAT GAATGCCTTC ATCAAGACTG CTCACAAGAA GCCCATCGAC 
CTGCGGGCCA TCGGGAAGCT GCCCATTGCC ATGAGAGCCC TCACCAACTA CCAGCGACTC 
TGCTTGGCCT TCGATGCCCA GGCGCGGAAG GACACACAGA GCCAGCAGGG TGCCCGGGCC 
ATCTGGAGGG CTCTCTGTCA TGCCTTTGGG AGACGGCTGG TCCTCAGCAG CACATTCCGT 
ATCCTGGCCG ACCTCCTGGG CTTTGCTGGG CCACTCTGCA TCTTCGGGAT CGTGGACCAC 
CTCGGGAAGG AGAACCACGT CTTCCAGCCC AAGACACAGT TTCTTGGAGT TTACTTTGTC 
TCATCCCAAG AGTTCCTCGG CAATGCCTAT GTCTTGGCTG TTCTTCTGTT CCTTGCCCTC 
CTGCTGCAAA GGACCTTTCT ACAAGCCTCG TACTACGTTG CCATTGAAAC TGGGATCAAC 
CTGAGAGGAG CAATCCAGAC CAAGATTTAC AATAAGATCA TGCACTTGTC TACTTCCAAC 
CTGTCCATGG GGGAAATGAC TGCTGGGCAG ATCTGCAACC TGGTGGCCAT CGACACCAAC 
CAGCTCATGT GGTTTTTCTT CTTATGCCCA AACCTCTGGG CTATGCCGGT ACAGATCATT 
GTGGGCGTGA TCCTCCTCTA CTACATCCTT GGGGTCAGCG CCTTGATTGG AGCGGCTGTC 
ATCATTCTGC TGGCTCCTGT ACAGTACTTT GTGGCCACCA AGCTGTCCCA GGCACAGCGG 
AGCACCCTGG AATATTCCAA TGAGAGGCTG AAGCAGACCA ATGAGATGCT CCGGGGCATC 
AAGTTGCTCA AGCTCTATGC GTGGGAGAAC ATCTTCTGCT CCAGGGTGGA GAAGACACGC 
AGGAAGGAAA TGACCAGCCT CAGGGCCTTC GCTGTCTACA CCTCCATCTC CATCTTCATG 
AACACAGCTA TCCCCATCGC TGCTGTCCTC ATCACCTTCG TGGGCCACGT CAGCTTCTTC 
AAAGAGTCGG ACTTCTCGCC CTCGGTGGCC TTTGCCTCTC TCTCTCTCTT CCACATCCTG 
GTCACACCGC TGTTCCTGCT GTCTAGTGTG GTTCGGTCCA CTGTCAAGGC CCTGGTGAGC 
GTGCAAAAGC TGAGTGAGTT CCTGTCCAGT GCAGAGATCC GTGAGGAACA GTGTGCCCCC 
CGAGAGCCCG CACCCCAAGG CCAAGCGGGC AAGTACCAGG CGGTGCCCCT CAAGGTCGTA 
AACCGCAAGC GCCCAGCCCG AGAAGAAGTC CGGGACCTCT TGGGCCCACT GCAGAGGCTG 
ACTCCCAGCA CGGATGGAGA CGCTGACAAC TTCTGTGTCC AGATCATCGG AGGCTTCTTC 
ACCTGGACCC CTGATGGAAT CCCCACCCTG TCCAACATCA CCATCCGTAT CCCCCGAGGT 
CAGCTGACCA TGATCGTGGG GCAGGTGGGC TGTGGCAAGT CCTCGCTCCT TCTGGCCACC 
CTGGGGGAGA TGCAGAAGGT CTCTGGAGCT GTCTTCTGGA ACAGCAGCCT TCCAGACAGC 
GAGGGAGAAG ACCCCAGCAA CCCAGAGCGG GAGACAGCGG CCGATTCGGA TGCCAGGAGC 
AGAGGCCCTG TGGCCTACGC ATCTCAGAAA CCATGGCTGC TAAATGCCAC TGTGGAGGAG 
AACATCACCT TCGAGAGTCC CTTCAATAAG CAACGGTACA AGATGGTCAT CGAAGCCTGC 
TCCCTGCAGC CAGACATAGA CATCCTGCCC CATGGAGACC AGACTCAGAT TGGGGAACGG 
GGCATCAACT TGTCTGGTGG TCAGCGTCAG CGAATCAGTG TAGCCCGAGC CCTCTACCAG 
CACACCAATG TTGTCTTTTT GGATGACCCT TTCTCGGCTC TGGATGTCCA TCTGAGTGAC 
CACCTAATGC AGGCTGGCAT CCTCGAGCTG CTCCGGGATG ACAAGAGGAC AGTGGTCTTG 
GTGACCCACA AGCTACAGTA CCTGCCTCAT GCTGACTGGA TCATTGCTAT GAAGGATGGC 
ACCATTCAGA GGGAGGGGAC ACTCAAGGAC TTCCAGAGGT CTGAGTGCCA GCTCTTTGAG 
CATTGGAAGA CCCTCATGAA CCGGCAGGAC CAAGAGCTGG AGAAGGAGAC AGTCATGGAG 
AGAAAAGCCC CAGAGCCATC TCAGGGCCTG CCCCGTGCCA TGTCCTCAAG AGATGGCCTT 
CTGCTGGATG AGGATGAGGA GGAAGAGGAG GCAGCCGAGA GCGAGGAAGA TGACAACTTA 
TCCTCTGTGC TGCATCAGCG AGCCAAGATC CCATGGCGAG CCTGCACCAA GTATTTGTCC 
TCTGCTGGCA TCCTGCTCCT GTCCCTGCTT GTCTTCTCCC AGCTGCTCAA GCACATGGTC 
TTGGTGGCCA TTGACTACTG GCTGGCCAAG TGGACGGACA GTGCCCTGGT CCTGAGCCCC 
GCCGCCAGGA ACTGCTCCCT CAGCCAGGAA TGTGCCCTGG ACCAATCTGT CTATGCCATG 
GTATTCACCG TGCTCTGCAG CCTGGGTATC GCGCTGTGCC TTGTCACCTC TGTCACTGTG 
GAGTGGACGG GACTGAAGGT GGCCAAGAGG CTGCATCGCA GCCTGCTCAA CCGTATCATC 
CTGGCTCCCA TGAGGTTCTT TGAGACCACG CCCCTGGGGA GTATCCTGAA CAGATTTTCA 
TCTGACTGTA ACACCATTGA CCAGCATATC CCGTCCACGC TGGAGTGCCT GAGCAGATCC 
ACCTTACTCT GTGTCTCCGC CCTGGCTGTC ATCTCCTACG TCACGCCTGT GTTCCTAGTG 
GCCCTCTTAC CCCTCGCCGT CGTGTGCTAC TTCATCCAGA AGTACTTCCG AGTGGCGTCC 
AGGGACCTGC AGCAGCTGGA CGACACAACA CAGCTCCCTC TGCTCTCACA CTTTGCTGAA 
ACTGTGGAAG GACTCACCAC CATCCGTGCC TTCAGGTACG AGGCCCGGTT CCAGCAGAAG 
CTCCTAGAGT ACACCGACTC CAACAACATT GCCTCTCTCT TCCTCACAGC AGCCAACAGG 
TGGCTGGAAG TCCGCATGGA GTACATCGGA GCATGCGTGG TACTCATCGC CGCTGCCACC 
TCCATCTCCA ACTCCCTACA CAGGGAGCTC TCAGCCGGCC TAGTAGGCCT GGGCCTCACC 
TATGCCTTGA TGGTCTCCAA CTACCTCAAC TGGATGGTGA GGAACCTGGC AGACATGGAG 
ATCCAACTGG GAGCTGTGAA GCGTATCCAC ACACTCCTGA AAACTGAGGC AGAGAGCTAT 
GAGGGGCTCC TGGCACCATC GCTGATCCCC AAGAACTGGC CAGACCAAGG GAAGATCCAA 
ATTCAAAACC TGAGTGTACG CTATGACAGC TCCCTGAAGC CCGTGCTGAA GCACGTCAAC 
GCCCTCATCT CCCCAGGACA GAAGATTGGG ATCTGCGGCC GCACAGGCAG TGGAAAATCC 
TCCTTCTCTC TCGCCTTTTT CCGAATGGTG GATATGTTTG AAGGGCGTAT CATCATCGAT 
GGCATTGACA TCGCCAAGCT GCCGCTGCAC ACGCTCCGCT CACGCCTGTC TATCATCCTA 
CAGGACCCTG TTCTCTTCAG TGGTACCATC AGATTCAACC TGGACCCAGA GAAGAAATGC 
TCAGACAGCA CGCTGTGGGA GGCTCTGGAG ATCGCTCAGC TGAAGCTGGT GGTGAAGGCC 
CTGCCAGGAG GCCTGGATGC CATCATCACG GAAGGAGGGG AGAATTTTAG CCAGGGCCAG 
AGGCAGCTGT TCTGCCTGGC CCGGGCCTTT GTGAGGAAGA CCAGCATCTT CATCATGGAT 
GAAGCAACTG CCTCCATCGA CATGGCTACG GAAAATATCC TCCAGAAGGT GGTGATGACA 
GCCTTCGCAG ACCGCACCGT GGTCACCATC GCGCACCGCG TGCACACCAT CCTGAGTGCA 
GACCTAGTGA TGGTCCTGAA GAGGGGCGCG ATCCTGGAGT TCGACAAGCC GGAAAAGCTT 
CTCAGCCAGA AGGACAGCGT CTTTGCCTCC TTTGTCCGCG CGGACAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757543.1
CDS	1..4671
Translation	MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCLAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEKTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSTDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK

Target ORF information:

RefSeq Version	XM_008759321.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ATP binding cassette subfamily C member 8 (Abcc8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759321.2

ORF Insert Sequence:

ATGCCTTTGG CCTTCTGCGG CACCGAGAAC CACTCGGCCG CCTACCGGGT GGACCAAGGC 
GTCCTCAACA ACGGCTGCTT CGTGGACGCG CTCAATGTGG TGCCACATGT CTTTCTGCTC 
TTCATCACCT TCCCCATCCT CTTCATCGGA TGGGGCAGCC AGAGCTCCAA GGTGCACATT 
CACCACAGCA CCTGGCTCCA TTTCCCGGGG CACAACCTGC GCTGGATCCT GACCTTCATA 
CTGCTCTTCG TCCTCGTGTG TGAGATCGCT GAGGGTATCC TGTCTGACGG GGTGACAGAA 
TCCCGCCACC TCCACTTATA CATGCCAGCT GGGATGGCAT TCATGGCTGC CATCACCTCT 
GTGGTCTACT ACCATAACAT TGAGACCTCT AACTTTCCCA AGCTGCTGAT TGCTCTGCTC 
ATCTACTGGA CCCTGGCCTT CATCACGAAG ACCATCAAGT TCGTCAAGTT CTACGACCAC 
GCCATTGGCT TCTCTCAGCT GCGCTTCTGC CTCACGGGGC TTCTGGTGAT CCTCTACGGG 
ATGCTGCTGC TTGTGGAGGT CAATGTCATC CGGGTGAGGC CCTTCGTTAA CCTGCTATCA 
AAGGGGACCT ACTGGTGGAT GAATGCCTTC ATCAAGACTG CTCACAAGAA GCCCATCGAC 
CTGCGGGCCA TCGGGAAGCT GCCCATTGCC ATGAGAGCCC TCACCAACTA CCAGCGACTC 
TGCTTGGCCT TCGATGCCCA GGCGCGGAAG GACACACAGA GCCAGCAGGG TGCCCGGGCC 
ATCTGGAGGG CTCTCTGTCA TGCCTTTGGG AGACGGCTGG TCCTCAGCAG CACATTCCGT 
ATCCTGGCCG ACCTCCTGGG CTTTGCTGGG CCACTCTGCA TCTTCGGGAT CGTGGACCAC 
CTCGGGAAGG AGAACCACGT CTTCCAGCCC AAGACACAGT TTCTTGGAGT TTACTTTGTC 
TCATCCCAAG AGTTCCTCGG CAATGCCTAT GTCTTGGCTG TTCTTCTGTT CCTTGCCCTC 
CTGCTGCAAA GGACCTTTCT ACAAGCCTCG TACTACGTTG CCATTGAAAC TGGGATCAAC 
CTGAGAGGAG CAATCCAGAC CAAGATTTAC AATAAGATCA TGCACTTGTC TACTTCCAAC 
CTGTCCATGG GGGAAATGAC TGCTGGGCAG ATCTGCAACC TGGTGGCCAT CGACACCAAC 
CAGCTCATGT GGTTTTTCTT CTTATGCCCA AACCTCTGGG CTATGCCGGT ACAGATCATT 
GTGGGCGTGA TCCTCCTCTA CTACATCCTT GGGGTCAGCG CCTTGATTGG AGCGGCTGTC 
ATCATTCTGC TGGCTCCTGT ACAGTACTTT GTGGCCACCA AGCTGTCCCA GGCACAGCGG 
AGCACCCTGG AATATTCCAA TGAGAGGCTG AAGCAGACCA ATGAGATGCT CCGGGGCATC 
AAGTTGCTCA AGCTCTATGC GTGGGAGAAC ATCTTCTGCT CCAGGGTGGA GAAGACACGC 
AGGAAGGAAA TGACCAGCCT CAGGGCCTTC GCTGTCTACA CCTCCATCTC CATCTTCATG 
AACACAGCTA TCCCCATCGC TGCTGTCCTC ATCACCTTCG TGGGCCACGT CAGCTTCTTC 
AAAGAGTCGG ACTTCTCGCC CTCGGTGGCC TTTGCCTCTC TCTCTCTCTT CCACATCCTG 
GTCACACCGC TGTTCCTGCT GTCTAGTGTG GTTCGGTCCA CTGTCAAGGC CCTGGTGAGC 
GTGCAAAAGC TGAGTGAGTT CCTGTCCAGT GCAGAGATCC GTGAGGAACA GTGTGCCCCC 
CGAGAGCCCG CACCCCAAGG CCAAGCGGGC AAGTACCAGG CGGTGCCCCT CAAGGTCGTA 
AACCGCAAGC GCCCAGCCCG AGAAGAAGTC CGGGACCTCT TGGGCCCACT GCAGAGGCTG 
ACTCCCAGCA CGGATGGAGA CGCTGACAAC TTCTGTGTCC AGATCATCGG AGGCTTCTTC 
ACCTGGACCC CTGATGGAAT CCCCACCCTG TCCAACATCA CCATCCGTAT CCCCCGAGGT 
CAGCTGACCA TGATCGTGGG GCAGGTGGGC TGTGGCAAGT CCTCGCTCCT TCTGGCCACC 
CTGGGGGAGA TGCAGAAGGT CTCTGGAGCT GTCTTCTGGA ACAGCAGCCT TCCAGACAGC 
GAGGGAGAAG ACCCCAGCAA CCCAGAGCGG GAGACAGCGG CCGATTCGGA TGCCAGGAGC 
AGAGGCCCTG TGGCCTACGC ATCTCAGAAA CCATGGCTGC TAAATGCCAC TGTGGAGGAG 
AACATCACCT TCGAGAGTCC CTTCAATAAG CAACGGTACA AGATGGTCAT CGAAGCCTGC 
TCCCTGCAGC CAGACATAGA CATCCTGCCC CATGGAGACC AGACTCAGAT TGGGGAACGG 
GGCATCAACT TGTCTGGTGG TCAGCGTCAG CGAATCAGTG TAGCCCGAGC CCTCTACCAG 
CACACCAATG TTGTCTTTTT GGATGACCCT TTCTCGGCTC TGGATGTCCA TCTGAGTGAC 
CACCTAATGC AGGCTGGCAT CCTCGAGCTG CTCCGGGATG ACAAGAGGAC AGTGGTCTTG 
GTGACCCACA AGCTACAGTA CCTGCCTCAT GCTGACTGGA TCATTGCTAT GAAGGATGGC 
ACCATTCAGA GGGAGGGGAC ACTCAAGGAC TTCCAGAGGT CTGAGTGCCA GCTCTTTGAG 
CATTGGAAGA CCCTCATGAA CCGGCAGGAC CAAGAGCTGG AGAAGGAGAC AGTCATGGAG 
AGAAAAGCCC CAGAGCCATC TCAGGGCCTG CCCCGTGCCA TGTCCTCAAG AGATGGCCTT 
CTGCTGGATG AGGATGAGGA GGAAGAGGAG GCAGCCGAGA GCGAGGAAGA TGACAACTTA 
TCCTCTGTGC TGCATCAGCG AGCCAAGATC CCATGGCGAG CCTGCACCAA GTATTTGTCC 
TCTGCTGGCA TCCTGCTCCT GTCCCTGCTT GTCTTCTCCC AGCTGCTCAA GCACATGGTC 
TTGGTGGCCA TTGACTACTG GCTGGCCAAG TGGACGGACA GTGCCCTGGT CCTGAGCCCC 
GCCGCCAGGA ACTGCTCCCT CAGCCAGGAA TGTGCCCTGG ACCAATCTGT CTATGCCATG 
GTATTCACCG TGCTCTGCAG CCTGGGTATC GCGCTGTGCC TTGTCACCTC TGTCACTGTG 
GAGTGGACGG GACTGAAGGT GGCCAAGAGG CTGCATCGCA GCCTGCTCAA CCGTATCATC 
CTGGCTCCCA TGAGGTTCTT TGAGACCACG CCCCTGGGGA GTATCCTGAA CAGATTTTCA 
TCTGACTGTA ACACCATTGA CCAGCATATC CCGTCCACGC TGGAGTGCCT GAGCAGATCC 
ACCTTACTCT GTGTCTCCGC CCTGGCTGTC ATCTCCTACG TCACGCCTGT GTTCCTAGTG 
GCCCTCTTAC CCCTCGCCGT CGTGTGCTAC TTCATCCAGA AGTACTTCCG AGTGGCGTCC 
AGGGACCTGC AGCAGCTGGA CGACACAACA CAGCTCCCTC TGCTCTCACA CTTTGCTGAA 
ACTGTGGAAG GACTCACCAC CATCCGTGCC TTCAGGTACG AGGCCCGGTT CCAGCAGAAG 
CTCCTAGAGT ACACCGACTC CAACAACATT GCCTCTCTCT TCCTCACAGC AGCCAACAGG 
TGGCTGGAAG TCCGCATGGA GTACATCGGA GCATGCGTGG TACTCATCGC CGCTGCCACC 
TCCATCTCCA ACTCCCTACA CAGGGAGCTC TCAGCCGGCC TAGTAGGCCT GGGCCTCACC 
TATGCCTTGA TGGTCTCCAA CTACCTCAAC TGGATGGTGA GGAACCTGGC AGACATGGAG 
ATCCAACTGG GAGCTGTGAA GCGTATCCAC ACACTCCTGA AAACTGAGGC AGAGAGCTAT 
GAGGGGCTCC TGGCACCATC GCTGATCCCC AAGAACTGGC CAGACCAAGG GAAGATCCAA 
ATTCAAAACC TGAGTGTACG CTATGACAGC TCCCTGAAGC CCGTGCTGAA GCACGTCAAC 
GCCCTCATCT CCCCAGGACA GAAGATTGGG ATCTGCGGCC GCACAGGCAG TGGAAAATCC 
TCCTTCTCTC TCGCCTTTTT CCGAATGGTG GATATGTTTG AAGGGCGTAT CATCATCGAT 
GGCATTGACA TCGCCAAGCT GCCGCTGCAC ACGCTCCGCT CACGCCTGTC TATCATCCTA 
CAGGACCCTG TTCTCTTCAG TGGTACCATC AGATTCAACC TGGACCCAGA GAAGAAATGC 
TCAGACAGCA CGCTGTGGGA GGCTCTGGAG ATCGCTCAGC TGAAGCTGGT GGTGAAGGCC 
CTGCCAGGAG GCCTGGATGC CATCATCACG GAAGGAGGGG AGAATTTTAG CCAGGGCCAG 
AGGCAGCTGT TCTGCCTGGC CCGGGCCTTT GTGAGGAAGA CCAGCATCTT CATCATGGAT 
GAAGCAACTG CCTCCATCGA CATGGCTACG GAAAATATCC TCCAGAAGGT GGTGATGACA 
GCCTTCGCAG ACCGCACCGT GGTCACCATC GCGCACCGCG TGCACACCAT CCTGAGTGCA 
GACCTAGTGA TGGTCCTGAA GAGGGGCGCG ATCCTGGAGT TCGACAAGCC GGAAAAGCTT 
CTCAGCCAGA AGGACAGCGT CTTTGCCTCC TTTGTCCGCG CGGACAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.
The Journal of biological chemistry292(42)17387-17398(2017 10)
Cooper PE,McClenaghan C,Chen X,Stary-Weinzinger A,Nichols CG

Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
eLife6(2017 01)
Martin GM,Yoshioka C,Rex EA,Fay JF,Xie Q,Whorton MR,Chen JZ,Shyng SL

SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.
PloS one11(8)e0148855(2016)
Nicholson JD,Guo Y,Bernstein SL

Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts.
Journal of neuropathology and experimental neurology74(8)835-49(2015 Aug)
Mehta RI,Tosun C,Ivanova S,Tsymbalyuk N,Famakin BM,Kwon MS,Castellani RJ,Gerzanich V,Simard JM

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity.
Bioscience reports35(4)(2015 Jul)
Fatehi M,Carter CR,Youssef N,Hunter BE,Holt A,Light PE

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Abcc8 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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