Acadvl cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Acadvl
Entrez Gene ID	25363
Full Name	acyl-CoA dehydrogenase, very long chain
Synonyms	VLCAD
General protein information	Preferred Names acyl-CoA dehydrogenase, very long chain Names very long-chain specific acyl-CoA dehydrogenase, mitochondrial VLCAD very-long-chain acyl-CoA dehydrogenase Very long chain Acyl-Coa dehydrogenase acyl-Coenzyme A dehydrogenase, very long chain
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24
Summary	catalyzes the beta-oxidation of long-chain fatty acids in mitochondrial fatty acid metabolism [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012891.2	NP_037023.1	very long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ACADVL	XP_003315394.1
Drosophila melanogaster (fruit fly)	CG7461	NP_611409.2
Canis lupus familiaris (dog)	ACADVL	XP_546581.3
Mus musculus (house mouse)	Acadvl	NP_059062.1
Caenorhabditis elegans (roundworm)	acdh-12	NP_001022062.1
Danio rerio (zebrafish)	acadvl	NP_997776.1
Homo sapiens (human)	ACADVL	NP_000009.1
Bos taurus (cattle)	ACADVL	NP_776919.1
Rattus norvegicus (Norway rat)	Acadvl	NP_037023.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008769	XP_314893.4

Gene Ontology
Bibliography

Related articles in PubMed

Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes.
Choi J, Ravipati A, Nimmagadda V, Schubert M, Castellani RJ, Russell JW
Mitochondrion1841-8(2014 Sep)

Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid β-oxidation.
Kim JE, Choi SI, Lee HR, Hwang IS, Lee YJ, An BS, Lee SH, Kim HJ, Kang BC, Hwang DY
Biological trace element research150(1-3)360-70(2012 Dec)

The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model.
Jia X, Naito H, Yetti H, Tamada H, Kitamori K, Hayashi Y, Yamagishi N, Wang D, Yanagiba Y, Ito Y, Wang J, Tanaka N, Ikeda K, Yamori Y, Nakajima T
Life sciences90(23-24)934-43(2012 Jun)

Asperuloside stimulates metabolic function in rats across several organs under high-fat diet conditions, acting like the major ingredient of Eucommia leaves with anti-obesity activity.
Fujikawa T, Hirata T, Hosoo S, Nakajima K, Wada A, Yurugi Y, Soya H, Matsui T, Yamaguchi A, Ogata M, Nishibe S
Journal of nutritional science1e10(2012)

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.
Buhrke T, Lengler I, Lampen A
Development, growth & differentiation53(3)411-26(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Acadvl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Acadvl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12596	NM_012891.2 Latest version!	Rattus norvegicus acyl-CoA dehydrogenase, very long chain (Acadvl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Acadvl ( NM_012891.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037023.1 Rattus norvegicus acyl-CoA dehydrogenase, very long chain (Acadvl), mRNA.

Price & Availability↑

CloneID	ORa12596
Clone ID Related Accession (Same CDS sequence)	NM_012891.2
Accession Version	NM_012891.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Rattus norvegicus(Norway rat)
Product	very long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D30647.1. On Aug 31, 2012 this sequence version replaced NM_012891.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D30647.1, BC087036.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGCAGTCGG CCCGGATGAC CCCGAGTGTG GGGCGACAAC TGCTGCGGCT GGGGGCCCGA 
AGCTCGCGGT CTGCTGCGCT TCAGGGACAA CCCCGGCCTA CCTCTGCCCA GCGACTTTAT 
GCCAGTGAGG CCACTCAGGC AGTTCTGGAA AAGCCAGAGA CCCTCTCCTC TGATGCTTCC 
ACCAGAGAAA AACCTGCCAG GGCGGAATCT AAGTCTTTTG CTGTGGGAAT GTTCAAAGGC 
CAGCTTACCA CCGACCAGGT GTTCCCATAC CCATCTGTGC TCAATGAAGG ACAGACACAA 
TTTCTCAAAG AGCTGGTGGG ACCAGTGGCC CGGTTCTTTG AAGAAGTGAA TGACCCTGCC 
AAGAATGACT CCTTGGAGAA GGTGGAGGAG GACACTTTGC AGGGACTCAA AGAACTGGGG 
GCATTTGGTC TGCAAGTACC CAGCGAGCTG GGTGGTTTGG GCCTCTCTAA TACCCAGTAC 
GCTCGCTTGG CAGAGATTGT GGGCATGCAT GACCTTGGTG TTAGCGTTAC CCTGGGAGCC 
CATCAGAGCA TCGGTTTCAA AGGCATCTTG CTCTATGGCA CAAAGGCCCA GAAGGAAAAA 
TACCTCCCCA GAGTGGCATC CGGGCAGGCT TTGGCGGCTT TCTGCCTGAC TGAGCCCTCG 
AGCGGGTCCG ATGTGGCCTC TATCCGAAGC TCAGCTGTAC CTAGCCCCTG TGGAAAGTAT 
TATACTCTCA ACGGAAGCAA GATCTGGATC AGTAATGGGG GTCTGGCAGA CATTTTCACT 
GTCTTTGCCA AAACGCCAAT TAAAGATGCA GCCACGGGGG CCGTGAAAGA GAAGATCACA 
GCTTTCGTAG TGGAACGGAG CTTTGGAGGG GTTACCCATG GGCTCCCCGA AAAGAAGATG 
GGCATCAAGG CATCTAACAC ATCAGAGGTG TACTTTGATG GAGTCAAGGT GCCAGCAGAG 
AATGTGCTAG GAGAAGTGGG AGATGGCTTC AAGGTTGCTG TCAACATCCT CAACAACGGA 
AGATTTGGGA TGGCTGCAAC CCTAGCAGGC ACCATGAAAG CCATCATTGC CAAGGCGGTT 
GATCATGCTA CTAACCGTAC CCAGTTTGGG GACAAAATTC ACAACTTTGG GGTGATCCAG 
GAAAAGCTGG CTCGGATGGC TATTCTGCAG TATGTGACTG AGTCCATGGC TTACATGCTG 
AGTGCCAACA TGGACCAGGG ATTCAAAGAC TTCCAGATAG AAGCTGCCAT CAGCAAAATC 
TTTGGCTCGG AGGCGGCCTG GAAAGTGACA GATGAGTGCA TCCAGATAAT GGGGGGCATG 
GGCTTCATGA AGGAACCAGG GGTAGAGCGT GTGCTCCGAG ATATTCGAAT CTTCCGGATC 
TTTGAAGGGA CAAATGACAT TCTTCGACTG TTTGTGGCTC TACAAGGCTG CATGGACAAA 
GGAAAGGAAC TCACGGGACT TGGTAATGCC CTAAAGAATC CTCTTGGAAA TGTTGGCCTC 
CTCATAGGAG AAGCAAGCAA ACAGCTGAGG CGGCGGACAG GGATTGGCAG TGGTCTGAGT 
CTCTCGGGAA TTGTCCACCC AGAGTTGAGT CGCAGTGGTG AACTGGCAGT GCAGGCTCTG 
GAACAATTTG CCACTGTAGT GGAGGCGAAG CTGATGAAGC ACAAGAAAGG GATTGTCAAT 
GAACAGTTCC TGCTGCAGCG ACTGGCAGAT GGAGCCATTG ACCTCTACGC CATGGTGGTG 
GTTCTCTCCA GAGCCTCAAG ATCCCTGAGT GAGGGCTACC CGACAGCACA GCATGAGAAA 
ATGCTCTGTG ATAGTTGGTG CATTGAGGCT GCAACACGGA TTCGAGAAAA CATGGCCAGC 
CTTCAGTCCA ACCCTCAGCA GCAGGAGCTC TTTCGTAACT TCAGAAGTAT CTCCAAGGCC 
ATGGTGGAGA ATGGTGGCCT GGTCACCAGT AACCCCCTTA GAGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037023.1
CDS	20..1987
Translation	MQSARMTPSVGRQLLRLGARSSRSAALQGQPRPTSAQRLYASEATQAVLEKPETLSSDASTREKPARAESKSFAVGMFKGQLTTDQVFPYPSVLNEGQTQFLKELVGPVARFFEEVNDPAKNDSLEKVEEDTLQGLKELGAFGLQVPSELGGLGLSNTQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQKEKYLPRVASGQALAAFCLTEPSSGSDVASIRSSAVPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPAENVLGEVGDGFKVAVNILNNGRFGMAATLAGTMKAIIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMAYMLSANMDQGFKDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDIRIFRIFEGTNDILRLFVALQGCMDKGKELTGLGNALKNPLGNVGLLIGEASKQLRRRTGIGSGLSLSGIVHPELSRSGELAVQALEQFATVVEAKLMKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSNPQQQELFRNFRSISKAMVENGGLVTSNPLRV

Target ORF information:

RefSeq Version	NM_012891.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus acyl-CoA dehydrogenase, very long chain (Acadvl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012891.2

ORF Insert Sequence:

ATGCAGTCGG CCCGGATGAC CCCGAGTGTG GGGCGACAAC TGCTGCGGCT GGGGGCCCGA 
AGCTCGCGGT CTGCTGCGCT TCAGGGACAA CCCCGGCCTA CCTCTGCCCA GCGACTTTAT 
GCCAGTGAGG CCACTCAGGC AGTTCTGGAA AAGCCAGAGA CCCTCTCCTC TGATGCTTCC 
ACCAGAGAAA AACCTGCCAG GGCGGAATCT AAGTCTTTTG CTGTGGGAAT GTTCAAAGGC 
CAGCTTACCA CCGACCAGGT GTTCCCATAC CCATCTGTGC TCAATGAAGG ACAGACACAA 
TTTCTCAAAG AGCTGGTGGG ACCAGTGGCC CGGTTCTTTG AAGAAGTGAA TGACCCTGCC 
AAGAATGACT CCTTGGAGAA GGTGGAGGAG GACACTTTGC AGGGACTCAA AGAACTGGGG 
GCATTTGGTC TGCAAGTACC CAGCGAGCTG GGTGGTTTGG GCCTCTCTAA TACCCAGTAC 
GCTCGCTTGG CAGAGATTGT GGGCATGCAT GACCTTGGTG TTAGCGTTAC CCTGGGAGCC 
CATCAGAGCA TCGGTTTCAA AGGCATCTTG CTCTATGGCA CAAAGGCCCA GAAGGAAAAA 
TACCTCCCCA GAGTGGCATC CGGGCAGGCT TTGGCGGCTT TCTGCCTGAC TGAGCCCTCG 
AGCGGGTCCG ATGTGGCCTC TATCCGAAGC TCAGCTGTAC CTAGCCCCTG TGGAAAGTAT 
TATACTCTCA ACGGAAGCAA GATCTGGATC AGTAATGGGG GTCTGGCAGA CATTTTCACT 
GTCTTTGCCA AAACGCCAAT TAAAGATGCA GCCACGGGGG CCGTGAAAGA GAAGATCACA 
GCTTTCGTAG TGGAACGGAG CTTTGGAGGG GTTACCCATG GGCTCCCCGA AAAGAAGATG 
GGCATCAAGG CATCTAACAC ATCAGAGGTG TACTTTGATG GAGTCAAGGT GCCAGCAGAG 
AATGTGCTAG GAGAAGTGGG AGATGGCTTC AAGGTTGCTG TCAACATCCT CAACAACGGA 
AGATTTGGGA TGGCTGCAAC CCTAGCAGGC ACCATGAAAG CCATCATTGC CAAGGCGGTT 
GATCATGCTA CTAACCGTAC CCAGTTTGGG GACAAAATTC ACAACTTTGG GGTGATCCAG 
GAAAAGCTGG CTCGGATGGC TATTCTGCAG TATGTGACTG AGTCCATGGC TTACATGCTG 
AGTGCCAACA TGGACCAGGG ATTCAAAGAC TTCCAGATAG AAGCTGCCAT CAGCAAAATC 
TTTGGCTCGG AGGCGGCCTG GAAAGTGACA GATGAGTGCA TCCAGATAAT GGGGGGCATG 
GGCTTCATGA AGGAACCAGG GGTAGAGCGT GTGCTCCGAG ATATTCGAAT CTTCCGGATC 
TTTGAAGGGA CAAATGACAT TCTTCGACTG TTTGTGGCTC TACAAGGCTG CATGGACAAA 
GGAAAGGAAC TCACGGGACT TGGTAATGCC CTAAAGAATC CTCTTGGAAA TGTTGGCCTC 
CTCATAGGAG AAGCAAGCAA ACAGCTGAGG CGGCGGACAG GGATTGGCAG TGGTCTGAGT 
CTCTCGGGAA TTGTCCACCC AGAGTTGAGT CGCAGTGGTG AACTGGCAGT GCAGGCTCTG 
GAACAATTTG CCACTGTAGT GGAGGCGAAG CTGATGAAGC ACAAGAAAGG GATTGTCAAT 
GAACAGTTCC TGCTGCAGCG ACTGGCAGAT GGAGCCATTG ACCTCTACGC CATGGTGGTG 
GTTCTCTCCA GAGCCTCAAG ATCCCTGAGT GAGGGCTACC CGACAGCACA GCATGAGAAA 
ATGCTCTGTG ATAGTTGGTG CATTGAGGCT GCAACACGGA TTCGAGAAAA CATGGCCAGC 
CTTCAGTCCA ACCCTCAGCA GCAGGAGCTC TTTCGTAACT TCAGAAGTAT CTCCAAGGCC 
ATGGTGGAGA ATGGTGGCCT GGTCACCAGT AACCCCCTTA GAGTCTGA