Cyp17a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cyp17a1
Entrez Gene ID	25146
Full Name	cytochrome P450, family 17, subfamily a, polypeptide 1
Synonyms	Cyp17
General protein information	Preferred Names cytochrome P450, family 17, subfamily a, polypeptide 1 Names steroid 17-alpha-hydroxylase/17,20 lyase 17-alpha-hydroxyprogesterone aldolase CYPXVII Cytochrome P450, subfamily XVII P450-C17 P45017alpha P450c17 cytochrome P450 17A1 cytochrome P450, subfamily 17 cytochrome P450-C17 cytochrome P450c17
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q54
Summary	steroid hydroxylase that comprises a main component of the steroidogenic pathway; activity culminates in corticosteriod and androgen production in adrenal gland and sex steroid production in gonads [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006231435.3	XP_006231497.1	steroid 17-alpha-hydroxylase/17,20 lyase isoform X1
NM_012753.2	NP_036885.1	steroid 17-alpha-hydroxylase/17,20 lyase precursor
XM_006231434.3	XP_006231496.1	steroid 17-alpha-hydroxylase/17,20 lyase isoform X1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	CYP17A1	NP_001035322.1
Arabidopsis thaliana (thale cress)	CYP706A3	NP_199275.1
Canis lupus familiaris (dog)	CYP17A1	XP_535000.3
Arabidopsis thaliana (thale cress)	CYP706A4	NP_192967.1
Arabidopsis thaliana (thale cress)	CYP706A2	NP_194002.1
Homo sapiens (human)	CYP17A1	NP_000093.1
Bos taurus (cattle)	CYP17A1	NP_776729.1
Arabidopsis thaliana (thale cress)	CYP706A6	NP_192969.4
Arabidopsis thaliana (thale cress)	CYP706A5	NP_192968.3
Arabidopsis thaliana (thale cress)	CYP706A1	NP_567665.2
Oryza sativa (rice)	Os08g0547900	NP_001062431.2
Mus musculus (house mouse)	Cyp17a1	NP_031835.3
Oryza sativa (rice)	Os01g0700500	NP_001043985.2
Pan troglodytes (chimpanzee)	CYP17A1	NP_001009052.1
Rattus norvegicus (Norway rat)	Cyp17a1	NP_036885.1
Arabidopsis thaliana (thale cress)	CYP706A7	NP_192970.1

Gene Ontology
Bibliography

Related articles in PubMed

A review of the literature on common CYP17A1 mutations in adults with 17-hydroxylase/17,20-lyase deficiency, a case series of such mutations among Koreans and functional characteristics of a novel mutation.
Kim YM, Kang M, Choi JH, Lee BH, Kim GH, Ohn JH, Kim SY, Park MS, Yoo HW
Metabolism: clinical and experimental63(1)42-9(2014 Jan)

Stimulation of estradiol biosynthesis by tributyltin in rat hippocampal slices.
Munetsuna E, Hattori M, Yamazaki T
Endocrine research39(4)168-72(2014)

Increased expression of P450scc and CYP17 in development of endogenous hyperandrogenism in a rat model of PCOS.
Li H, Chen Y, Yan LY, Qiao J
Endocrine43(1)184-90(2013 Feb)

Cytochrome P450 17α-hydroxylase/C(17,20)-lyase immunoreactivity and molecular expression in the cerebellar nuclei of adult male rats.
Manca P, Caria MA, Blasi J, Martín-Satué M, Mameli O
Journal of chemical neuroanatomy45(1-2)18-25(2012 Oct)

Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001.
DeVore NM, Scott EE
Nature482(7383)116-9(2012 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cyp17a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cyp17a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa00841	NM_012753.2 Latest version!	Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa24118	XM_006231434.3 Latest version!	Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa24118	XM_006231435.3 Latest version!	Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cyp17a1 ( NM_012753.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036885.1 Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), mRNA.

Price & Availability↑

CloneID	ORa00841
Clone ID Related Accession (Same CDS sequence)	NM_012753.2
Accession Version	NM_012753.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569600000000
Organism	Rattus norvegicus(Norway rat)
Product	steroid 17-alpha-hydroxylase/17,20 lyase precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X14086.1. On Aug 31, 2012 this sequence version replaced NM_012753.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X14086.1, M31681.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906355, SAMN01906356 [ECO:0000348] ##Evidence-Data-END##

ATGTGGGAAC TTGTGGGTCT CTTGCTGCTC ATCCTAGCCT ATTTCTTTTG GGTCAAGTCA 
AAGACGCCCG GTGCCAAGCT CCCCAGGAGC CTTCCATCCC TGCCCCTGGT GGGCAGTCTG 
CCGTTTCTCC CCAGACGTGG TCATATGCAT GTCAACTTCT TCAAGCTACA GGAAAAGTAT 
GGTCCCATCT ATTCTCTTCG CCTGGGTACC ACAACTACAG TGATCATCGG CCACTATCAG 
CTGGCCAGGG AGGTGCTCAT CAAGAAGGGA AAAGAATTCT CTGGTCGGCC CCAGATGGTG 
ACTCAAAGCC TCTTGTCGGA CCAAGGGAAA GGCGTGGCCT TTGCAGATGC TGGTAGCTCC 
TGGCACCTGC ACCGGAAGTT GGTGTTCAGC ACCTTTTCCC TGTTCAAGGA TGGCCAGAAA 
CTGGAGAAGC TAATCTGTCA GGAAGCCAAG TCACTGTGTG ATATGATGCT GGCACACGAC 
AAGGAGTCCA TAGACCTGTC CACGCCTATC TTCATGTCAG TAACCAACAT CATCTGTGCT 
ATCTGCTTCA ACATCTCTTA TGAGAAAAAT GATCCAAAAC TGACCGCCAT AAAGACCTTT 
ACTGAGGGTA TCGTGGATGC CACGGGCGAC AGAAATCTGG TGGACATATT CCCATGGTTG 
ACGATTTTTC CCAACAAAGG CTTGGAGGTG ATAAAGGGTT ATGCCAAAGT TCGAAATGAA 
GTACTGACTG GAATATTTGA AAAGTGCAGG GAGAAGTTCG ACAGTCAGTC TATCTCCAGC 
CTGACGGACA TTCTGATTCA AGCCAAGATG AATTCAGACA ACAACAACAG CTGTGAAGGC 
CGGGACCCAG ATGTGTTTTC AGATAGGCAC ATCCTTGCCA CGGTGGGAGA CATCTTTGGG 
GCGGGCATAG AGACAACTAC CACTGTGCTC AAGTGGATCC TGGCTTTCCT GGTGCACAAT 
CCTGAGGTGA AGAAGAAGAT CCAAAAGGAG ATTGACCAGT ACGTAGGCTT CAGCCGAACA 
CCAACTTTCA ATGACCGGTC TCACCTCCTC ATGCTGGAGG CCACTATCCG AGAAGTGCTG 
CGTATCAGGC CGGTGGCTCC CATGCTCATC CCCCACAAGG CTAACGTTGA CTCCAGCATT 
GGAGAGTTTA CTGTCCCCAA GGACACACAT GTGGTCGTCA ATCTCTGGGC ACTGCATCAC 
GATGAGAATG AATGGGACCA GCCAGATCAG TTCATGCCTG AACGCTTCTT AGATCCAACG 
GGAAGCCATC TCATTACACC CACGCAGAGT TACTTGCCCT TCGGAGCTGG TCCCCGATCC 
TGCATCGGAG AGGCTCTGGC CCGTCAGGAG CTCTTTGTCT TCACGGCCTT GCTACTGCAG 
AGGTTTGACT TGGATGTGTC AGATGATAAA CAACTGCCCC GCCTGGAGGG TGATCCCAAG 
GTAGTCTTTC TGATCGACCC TTTCAAAGTA AAGATCACGG TGCGCCAGGC ATGGATGGAT 
GCACAGGCTG AGGTTAGCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036885.1
CDS	31..1554
Translation	MWELVGLLLLILAYFFWVKSKTPGAKLPRSLPSLPLVGSLPFLPRRGHMHVNFFKLQEKYGPIYSLRLGTTTTVIIGHYQLAREVLIKKGKEFSGRPQMVTQSLLSDQGKGVAFADAGSSWHLHRKLVFSTFSLFKDGQKLEKLICQEAKSLCDMMLAHDKESIDLSTPIFMSVTNIICAICFNISYEKNDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNKGLEVIKGYAKVRNEVLTGIFEKCREKFDSQSISSLTDILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPDQFMPERFLDPTGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVSDDKQLPRLEGDPKVVFLIDPFKVKITVRQAWMDAQAEVST

Target ORF information:

RefSeq Version	NM_012753.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012753.2

ORF Insert Sequence:

ATGTGGGAAC TTGTGGGTCT CTTGCTGCTC ATCCTAGCCT ATTTCTTTTG GGTCAAGTCA 
AAGACGCCCG GTGCCAAGCT CCCCAGGAGC CTTCCATCCC TGCCCCTGGT GGGCAGTCTG 
CCGTTTCTCC CCAGACGTGG TCATATGCAT GTCAACTTCT TCAAGCTACA GGAAAAGTAT 
GGTCCCATCT ATTCTCTTCG CCTGGGTACC ACAACTACAG TGATCATCGG CCACTATCAG 
CTGGCCAGGG AGGTGCTCAT CAAGAAGGGA AAAGAATTCT CTGGTCGGCC CCAGATGGTG 
ACTCAAAGCC TCTTGTCGGA CCAAGGGAAA GGCGTGGCCT TTGCAGATGC TGGTAGCTCC 
TGGCACCTGC ACCGGAAGTT GGTGTTCAGC ACCTTTTCCC TGTTCAAGGA TGGCCAGAAA 
CTGGAGAAGC TAATCTGTCA GGAAGCCAAG TCACTGTGTG ATATGATGCT GGCACACGAC 
AAGGAGTCCA TAGACCTGTC CACGCCTATC TTCATGTCAG TAACCAACAT CATCTGTGCT 
ATCTGCTTCA ACATCTCTTA TGAGAAAAAT GATCCAAAAC TGACCGCCAT AAAGACCTTT 
ACTGAGGGTA TCGTGGATGC CACGGGCGAC AGAAATCTGG TGGACATATT CCCATGGTTG 
ACGATTTTTC CCAACAAAGG CTTGGAGGTG ATAAAGGGTT ATGCCAAAGT TCGAAATGAA 
GTACTGACTG GAATATTTGA AAAGTGCAGG GAGAAGTTCG ACAGTCAGTC TATCTCCAGC 
CTGACGGACA TTCTGATTCA AGCCAAGATG AATTCAGACA ACAACAACAG CTGTGAAGGC 
CGGGACCCAG ATGTGTTTTC AGATAGGCAC ATCCTTGCCA CGGTGGGAGA CATCTTTGGG 
GCGGGCATAG AGACAACTAC CACTGTGCTC AAGTGGATCC TGGCTTTCCT GGTGCACAAT 
CCTGAGGTGA AGAAGAAGAT CCAAAAGGAG ATTGACCAGT ACGTAGGCTT CAGCCGAACA 
CCAACTTTCA ATGACCGGTC TCACCTCCTC ATGCTGGAGG CCACTATCCG AGAAGTGCTG 
CGTATCAGGC CGGTGGCTCC CATGCTCATC CCCCACAAGG CTAACGTTGA CTCCAGCATT 
GGAGAGTTTA CTGTCCCCAA GGACACACAT GTGGTCGTCA ATCTCTGGGC ACTGCATCAC 
GATGAGAATG AATGGGACCA GCCAGATCAG TTCATGCCTG AACGCTTCTT AGATCCAACG 
GGAAGCCATC TCATTACACC CACGCAGAGT TACTTGCCCT TCGGAGCTGG TCCCCGATCC 
TGCATCGGAG AGGCTCTGGC CCGTCAGGAG CTCTTTGTCT TCACGGCCTT GCTACTGCAG 
AGGTTTGACT TGGATGTGTC AGATGATAAA CAACTGCCCC GCCTGGAGGG TGATCCCAAG 
GTAGTCTTTC TGATCGACCC TTTCAAAGTA AAGATCACGG TGCGCCAGGC ATGGATGGAT 
GCACAGGCTG AGGTTAGCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp17a1 ( XM_006231435.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231497.1 Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa24118
Clone ID Related Accession (Same CDS sequence)	XM_006231435.3 , XM_006231434.3
Accession Version	XM_006231435.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	steroid 17-alpha-hydroxylase/17,20 lyase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231435.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGGAAC TTGTGGGTCT CTTGCTGCTC ATCCTAGCCT ATTTCTTTTG GGTCAAGTCA 
AAGACGCCCG GTGCCAAGCT CCCCAGGAGC CTTCCATCCC TGCCCCTGGT GGGCAGTCTG 
CCGTTTCTCC CCAGACGTGG TCATATGCAT GTCAACTTCT TCAAGCTACA GGAAAAGTAT 
GGTCCCATCT ATTCTCTTCG CCTGGGTACC ACAACTACAG TGATCATCGG CCACTATCAG 
CTGGCCAGGG AGGTGCTCAT CAAGAAGGGA AAAGAATTCT CTGGTCGGCC CCAGATGGTG 
ACTCAAAGCC TCTTGTCGGA CCAAGGGAAA GGCGTGGCCT TTGCAGATGC TGGTAGCTCC 
TGGCACCTGC ACCGGAAGTT GGTGTTCAGC ACCTTTTCCC TGTTCAAGGA TGGCCAGAAA 
CTGGAGAAGC TAATCTGTCA GGAAGCCAAG TCACTGTGTG ATATGATGCT GGCACACGAC 
AAGGAGTCCA TAGACCTGTC CACGCCTATC TTCATGTCAG TAACCAACAT CATCTGTGCT 
ATCTGCTTCA ACATCTCTTA TGAGAAAAAG GATCCAAAAC TGACCGCCAT AAAGACCTTT 
ACTGAGGGTA TCGTGGATGC CACGGGCGAC AGAAATCTGG TGGACATATT CCCATGGTTG 
ACGATTTTTC CCAACAAAGG CTTGGAGGTG ATAAAGGGTT ATGCCAAAGT TCGAAATGAA 
GTACTGACTG GAATATTTGA AAAGTGCAGG GAGAAGTTCG ACAGTCAGTC TATCTCCAGC 
CTGACGGACA TTCTGATTCA AGCCAAGATG AATTCAGACA ACAACAACAG CTGTGAAGGC 
CGGGACCCAG ATGTGTTTTC AGATAGGCAC ATCCTTGCCA CGGTGGGAGA CATCTTTGGG 
GCGGGCATAG AGACAACTAC CACTGTGCTC AAGTGGATCC TGGCTTTCCT GGTGCACAAT 
CCTGAGGTGA AGAAGAAGAT CCAAAAGGAG ATTGACCAGT ACGTAGGCTT CAGCCGAACA 
CCAACTTTCA ATGACCGGTC TCACCTCCTC ATGCTGGAGG CCACTATCCG AGAAGTGCTG 
CGTATCAGGC CGGTGGCTCC CATGCTCATC CCCCACAAGG CTAACGTTGA CTCCAGCATT 
GGAGAGTTTA CTGTCCCCAA GGACACACAT GTGGTCGTCA ATCTCTGGGC ACTGCATCAC 
GATGAGAATG AATGGGACCA GCCAGATCAG TTCATGCCTG AACGCTTCTT AGATCCAACG 
GGAAGCCATC TCATTACACC CACGCAGAGT TACTTGCCCT TCGGAGCTGG TCCCCGATCC 
TGCATCGGAG AGGCTCTGGC CCGTCAGGAG CTCTTTGTCT TCACGGCCTT GCTACTGCAG 
AGGTTTGACT TGGATGTGTC AGATGATAAA CAACTGCCCC GCCTGGAGGG TGATCCCAAG 
GTAGTCTTTC TGATCGACCC TTTCAAAGTA AAGATCACGG TGCGCCAGGC ATGGATGGAT 
GCACAGGCTG AGGTTAGCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231497.1
CDS	325..1848
Translation	MWELVGLLLLILAYFFWVKSKTPGAKLPRSLPSLPLVGSLPFLPRRGHMHVNFFKLQEKYGPIYSLRLGTTTTVIIGHYQLAREVLIKKGKEFSGRPQMVTQSLLSDQGKGVAFADAGSSWHLHRKLVFSTFSLFKDGQKLEKLICQEAKSLCDMMLAHDKESIDLSTPIFMSVTNIICAICFNISYEKKDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNKGLEVIKGYAKVRNEVLTGIFEKCREKFDSQSISSLTDILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPDQFMPERFLDPTGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVSDDKQLPRLEGDPKVVFLIDPFKVKITVRQAWMDAQAEVST

Target ORF information:

RefSeq Version	XM_006231435.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231435.3

ORF Insert Sequence:

ATGTGGGAAC TTGTGGGTCT CTTGCTGCTC ATCCTAGCCT ATTTCTTTTG GGTCAAGTCA 
AAGACGCCCG GTGCCAAGCT CCCCAGGAGC CTTCCATCCC TGCCCCTGGT GGGCAGTCTG 
CCGTTTCTCC CCAGACGTGG TCATATGCAT GTCAACTTCT TCAAGCTACA GGAAAAGTAT 
GGTCCCATCT ATTCTCTTCG CCTGGGTACC ACAACTACAG TGATCATCGG CCACTATCAG 
CTGGCCAGGG AGGTGCTCAT CAAGAAGGGA AAAGAATTCT CTGGTCGGCC CCAGATGGTG 
ACTCAAAGCC TCTTGTCGGA CCAAGGGAAA GGCGTGGCCT TTGCAGATGC TGGTAGCTCC 
TGGCACCTGC ACCGGAAGTT GGTGTTCAGC ACCTTTTCCC TGTTCAAGGA TGGCCAGAAA 
CTGGAGAAGC TAATCTGTCA GGAAGCCAAG TCACTGTGTG ATATGATGCT GGCACACGAC 
AAGGAGTCCA TAGACCTGTC CACGCCTATC TTCATGTCAG TAACCAACAT CATCTGTGCT 
ATCTGCTTCA ACATCTCTTA TGAGAAAAAG GATCCAAAAC TGACCGCCAT AAAGACCTTT 
ACTGAGGGTA TCGTGGATGC CACGGGCGAC AGAAATCTGG TGGACATATT CCCATGGTTG 
ACGATTTTTC CCAACAAAGG CTTGGAGGTG ATAAAGGGTT ATGCCAAAGT TCGAAATGAA 
GTACTGACTG GAATATTTGA AAAGTGCAGG GAGAAGTTCG ACAGTCAGTC TATCTCCAGC 
CTGACGGACA TTCTGATTCA AGCCAAGATG AATTCAGACA ACAACAACAG CTGTGAAGGC 
CGGGACCCAG ATGTGTTTTC AGATAGGCAC ATCCTTGCCA CGGTGGGAGA CATCTTTGGG 
GCGGGCATAG AGACAACTAC CACTGTGCTC AAGTGGATCC TGGCTTTCCT GGTGCACAAT 
CCTGAGGTGA AGAAGAAGAT CCAAAAGGAG ATTGACCAGT ACGTAGGCTT CAGCCGAACA 
CCAACTTTCA ATGACCGGTC TCACCTCCTC ATGCTGGAGG CCACTATCCG AGAAGTGCTG 
CGTATCAGGC CGGTGGCTCC CATGCTCATC CCCCACAAGG CTAACGTTGA CTCCAGCATT 
GGAGAGTTTA CTGTCCCCAA GGACACACAT GTGGTCGTCA ATCTCTGGGC ACTGCATCAC 
GATGAGAATG AATGGGACCA GCCAGATCAG TTCATGCCTG AACGCTTCTT AGATCCAACG 
GGAAGCCATC TCATTACACC CACGCAGAGT TACTTGCCCT TCGGAGCTGG TCCCCGATCC 
TGCATCGGAG AGGCTCTGGC CCGTCAGGAG CTCTTTGTCT TCACGGCCTT GCTACTGCAG 
AGGTTTGACT TGGATGTGTC AGATGATAAA CAACTGCCCC GCCTGGAGGG TGATCCCAAG 
GTAGTCTTTC TGATCGACCC TTTCAAAGTA AAGATCACGG TGCGCCAGGC ATGGATGGAT 
GCACAGGCTG AGGTTAGCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cyp17a1 ( XM_006231434.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231496.1 Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24118
Clone ID Related Accession (Same CDS sequence)	XM_006231435.3 , XM_006231434.3
Accession Version	XM_006231434.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	steroid 17-alpha-hydroxylase/17,20 lyase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231434.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGGAAC TTGTGGGTCT CTTGCTGCTC ATCCTAGCCT ATTTCTTTTG GGTCAAGTCA 
AAGACGCCCG GTGCCAAGCT CCCCAGGAGC CTTCCATCCC TGCCCCTGGT GGGCAGTCTG 
CCGTTTCTCC CCAGACGTGG TCATATGCAT GTCAACTTCT TCAAGCTACA GGAAAAGTAT 
GGTCCCATCT ATTCTCTTCG CCTGGGTACC ACAACTACAG TGATCATCGG CCACTATCAG 
CTGGCCAGGG AGGTGCTCAT CAAGAAGGGA AAAGAATTCT CTGGTCGGCC CCAGATGGTG 
ACTCAAAGCC TCTTGTCGGA CCAAGGGAAA GGCGTGGCCT TTGCAGATGC TGGTAGCTCC 
TGGCACCTGC ACCGGAAGTT GGTGTTCAGC ACCTTTTCCC TGTTCAAGGA TGGCCAGAAA 
CTGGAGAAGC TAATCTGTCA GGAAGCCAAG TCACTGTGTG ATATGATGCT GGCACACGAC 
AAGGAGTCCA TAGACCTGTC CACGCCTATC TTCATGTCAG TAACCAACAT CATCTGTGCT 
ATCTGCTTCA ACATCTCTTA TGAGAAAAAG GATCCAAAAC TGACCGCCAT AAAGACCTTT 
ACTGAGGGTA TCGTGGATGC CACGGGCGAC AGAAATCTGG TGGACATATT CCCATGGTTG 
ACGATTTTTC CCAACAAAGG CTTGGAGGTG ATAAAGGGTT ATGCCAAAGT TCGAAATGAA 
GTACTGACTG GAATATTTGA AAAGTGCAGG GAGAAGTTCG ACAGTCAGTC TATCTCCAGC 
CTGACGGACA TTCTGATTCA AGCCAAGATG AATTCAGACA ACAACAACAG CTGTGAAGGC 
CGGGACCCAG ATGTGTTTTC AGATAGGCAC ATCCTTGCCA CGGTGGGAGA CATCTTTGGG 
GCGGGCATAG AGACAACTAC CACTGTGCTC AAGTGGATCC TGGCTTTCCT GGTGCACAAT 
CCTGAGGTGA AGAAGAAGAT CCAAAAGGAG ATTGACCAGT ACGTAGGCTT CAGCCGAACA 
CCAACTTTCA ATGACCGGTC TCACCTCCTC ATGCTGGAGG CCACTATCCG AGAAGTGCTG 
CGTATCAGGC CGGTGGCTCC CATGCTCATC CCCCACAAGG CTAACGTTGA CTCCAGCATT 
GGAGAGTTTA CTGTCCCCAA GGACACACAT GTGGTCGTCA ATCTCTGGGC ACTGCATCAC 
GATGAGAATG AATGGGACCA GCCAGATCAG TTCATGCCTG AACGCTTCTT AGATCCAACG 
GGAAGCCATC TCATTACACC CACGCAGAGT TACTTGCCCT TCGGAGCTGG TCCCCGATCC 
TGCATCGGAG AGGCTCTGGC CCGTCAGGAG CTCTTTGTCT TCACGGCCTT GCTACTGCAG 
AGGTTTGACT TGGATGTGTC AGATGATAAA CAACTGCCCC GCCTGGAGGG TGATCCCAAG 
GTAGTCTTTC TGATCGACCC TTTCAAAGTA AAGATCACGG TGCGCCAGGC ATGGATGGAT 
GCACAGGCTG AGGTTAGCAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231496.1
CDS	357..1880
Translation	MWELVGLLLLILAYFFWVKSKTPGAKLPRSLPSLPLVGSLPFLPRRGHMHVNFFKLQEKYGPIYSLRLGTTTTVIIGHYQLAREVLIKKGKEFSGRPQMVTQSLLSDQGKGVAFADAGSSWHLHRKLVFSTFSLFKDGQKLEKLICQEAKSLCDMMLAHDKESIDLSTPIFMSVTNIICAICFNISYEKKDPKLTAIKTFTEGIVDATGDRNLVDIFPWLTIFPNKGLEVIKGYAKVRNEVLTGIFEKCREKFDSQSISSLTDILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPDQFMPERFLDPTGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVSDDKQLPRLEGDPKVVFLIDPFKVKITVRQAWMDAQAEVST

Target ORF information:

RefSeq Version	XM_006231434.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231434.3

ORF Insert Sequence:

ATGTGGGAAC TTGTGGGTCT CTTGCTGCTC ATCCTAGCCT ATTTCTTTTG GGTCAAGTCA 
AAGACGCCCG GTGCCAAGCT CCCCAGGAGC CTTCCATCCC TGCCCCTGGT GGGCAGTCTG 
CCGTTTCTCC CCAGACGTGG TCATATGCAT GTCAACTTCT TCAAGCTACA GGAAAAGTAT 
GGTCCCATCT ATTCTCTTCG CCTGGGTACC ACAACTACAG TGATCATCGG CCACTATCAG 
CTGGCCAGGG AGGTGCTCAT CAAGAAGGGA AAAGAATTCT CTGGTCGGCC CCAGATGGTG 
ACTCAAAGCC TCTTGTCGGA CCAAGGGAAA GGCGTGGCCT TTGCAGATGC TGGTAGCTCC 
TGGCACCTGC ACCGGAAGTT GGTGTTCAGC ACCTTTTCCC TGTTCAAGGA TGGCCAGAAA 
CTGGAGAAGC TAATCTGTCA GGAAGCCAAG TCACTGTGTG ATATGATGCT GGCACACGAC 
AAGGAGTCCA TAGACCTGTC CACGCCTATC TTCATGTCAG TAACCAACAT CATCTGTGCT 
ATCTGCTTCA ACATCTCTTA TGAGAAAAAG GATCCAAAAC TGACCGCCAT AAAGACCTTT 
ACTGAGGGTA TCGTGGATGC CACGGGCGAC AGAAATCTGG TGGACATATT CCCATGGTTG 
ACGATTTTTC CCAACAAAGG CTTGGAGGTG ATAAAGGGTT ATGCCAAAGT TCGAAATGAA 
GTACTGACTG GAATATTTGA AAAGTGCAGG GAGAAGTTCG ACAGTCAGTC TATCTCCAGC 
CTGACGGACA TTCTGATTCA AGCCAAGATG AATTCAGACA ACAACAACAG CTGTGAAGGC 
CGGGACCCAG ATGTGTTTTC AGATAGGCAC ATCCTTGCCA CGGTGGGAGA CATCTTTGGG 
GCGGGCATAG AGACAACTAC CACTGTGCTC AAGTGGATCC TGGCTTTCCT GGTGCACAAT 
CCTGAGGTGA AGAAGAAGAT CCAAAAGGAG ATTGACCAGT ACGTAGGCTT CAGCCGAACA 
CCAACTTTCA ATGACCGGTC TCACCTCCTC ATGCTGGAGG CCACTATCCG AGAAGTGCTG 
CGTATCAGGC CGGTGGCTCC CATGCTCATC CCCCACAAGG CTAACGTTGA CTCCAGCATT 
GGAGAGTTTA CTGTCCCCAA GGACACACAT GTGGTCGTCA ATCTCTGGGC ACTGCATCAC 
GATGAGAATG AATGGGACCA GCCAGATCAG TTCATGCCTG AACGCTTCTT AGATCCAACG 
GGAAGCCATC TCATTACACC CACGCAGAGT TACTTGCCCT TCGGAGCTGG TCCCCGATCC 
TGCATCGGAG AGGCTCTGGC CCGTCAGGAG CTCTTTGTCT TCACGGCCTT GCTACTGCAG 
AGGTTTGACT TGGATGTGTC AGATGATAAA CAACTGCCCC GCCTGGAGGG TGATCCCAAG 
GTAGTCTTTC TGATCGACCC TTTCAAAGTA AAGATCACGG TGCGCCAGGC ATGGATGGAT 
GCACAGGCTG AGGTTAGCAC CTAG