Ampd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ampd1
Entrez Gene ID	25028
Full Name	adenosine monophosphate deaminase 1
Synonyms	Ampd01,RATAMPD01
General protein information	Preferred Names adenosine monophosphate deaminase 1 Names AMP deaminase 1 Ampd adenosine monophosphate deaminase 1 (isoform M) myoadenylate deaminase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	catalyzes the conversion of AMP to IMP in energy metabolism [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006233060.3	XP_006233122.1	AMP deaminase 1 isoform X1
NM_138876.1	NP_620231.1	AMP deaminase 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	AMPD1	NP_000027.2
Danio rerio (zebrafish)	ampd1	NP_957187.1
Macaca mulatta (Rhesus monkey)	AMPD1	XP_001111578.2
Xenopus tropicalis (tropical clawed frog)	ampd1	XP_002935821.2
Pan troglodytes (chimpanzee)	AMPD1	XP_513671.3
Mus musculus (house mouse)	Ampd1	NP_001028475.2
Gallus gallus (chicken)	AMPD1	XP_003642776.1
Bos taurus (cattle)	AMPD1	NP_001093819.1
Rattus norvegicus (Norway rat)	Ampd1	NP_620231.1
Canis lupus familiaris (dog)	AMPD1	XP_848536.2

Gene Ontology
Bibliography

Related articles in PubMed

Variation in the gene for muscle-specific AMP deaminase is associated with insulin clearance, a highly heritable trait.
Goodarzi MO, Taylor KD, Guo X, Quiñones MJ, Cui J, Li X, Hang T, Yang H, Holmes E, Hsueh WA, Olefsky J, Rotter JI
Diabetes54(4)1222-7(2005 Apr)

High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
Genome research14(4)750-7(2004 Apr)

Improved radiation hybrid map of rat chromosome 2: colocalization of the genes encoding corticotropin-releasing hormone and IL6-receptor with quantitative trait loci regulating the inflammatory response.
Laes JF, Ravoet M, Quan X, Van Vooren P, Szpirer J, Szpirer C
Cytogenetics and cell genetics92(1-2)130-3(2001)

Novel aspects of tetramer assembly and N-terminal domain structure and function are revealed by recombinant expression of human AMP deaminase isoforms.
Mahnke-Zizelman DK, Tullson PC, Sabina RL
The Journal of biological chemistry273(52)35118-25(1998 Dec)

Control of AMP deaminase 1 binding to myosin heavy chain.
Hisatome I, Morisaki T, Kamma H, Sugama T, Morisaki H, Ohtahara A, Holmes EW
The American journal of physiology275(3)C870-81(1998 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ampd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ampd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01841	NM_138876.1 Latest version!	Rattus norvegicus adenosine monophosphate deaminase 1 (Ampd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
ORa25125	XM_006233060.3 Latest version!	Rattus norvegicus adenosine monophosphate deaminase 1 (Ampd1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ampd1 ( NM_138876.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620231.1 Rattus norvegicus adenosine monophosphate deaminase 1 (Ampd1), mRNA.

Price & Availability↑

CloneID	ORa01841
Clone ID Related Accession (Same CDS sequence)	NM_138876.1
Accession Version	NM_138876.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2244bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568908800000
Organism	Rattus norvegicus(Norway rat)
Product	AMP deaminase 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J02811.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J02811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689600, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGCCTCTGT TCAAACTTAC AGGTCAAGGA AAACAAATTG ATGATGCAAT GCGTAGCTTT 
GCTGAAAAAG TATTTGCCTC AGAAGTCAAA GATGAGGGAG GTCGGCACGA GATCTCCCCC 
TTCGACGTGG ATGAGATCTG CCCAATTTCC CTTCGTGAGA TGCAGGCCCA CATATTCCAC 
ATGGAGAACC TGTCCATGTC CATGGATGGC AGGAGGAAAA GGCGCTTCCA AGGACGGAAG 
ACTGTTAATT TGTCCATTCC GCAAAGTGAA ACGTCTTCTA CCAAACTGTC CCACATTGAA 
GAATTTATTT CTTCATCCCC GACCTATGAG AGTGTGCCTG ACTTCCAGAG GGTGCAGATC 
ACTGGTGACT ATGCCTCTGG GGTAACTGTT GAAGACTTTG AGGTGGTTTG TAAAGGTCTC 
TATCGGGCTT TGTGTATACG AGAGAAATAC ATGCAGAAGT CATTCCAGAG GTTCCCCAAG 
ACCCCCTCCA AGTACCTGAG GAACATCGAC GGCGAAGCTT TGGTAGCAAT CGAAAGCTTC 
TATCCAGTAT TTACCCCTCC TCCGAAGAAG GGAGAAGACC CCTTTCGCAG AGAAGACCTT 
CCCGCAAACC TGGGCTATCA CCTCAAGATG AAGGGTGGTG TGATTTACAT CTACCCTGAT 
GAAGCAGCAG CCAGCAGAGA TGAGCCCAAG CCCTACCCTT ACCCAAATCT GGATGACTTC 
CTGGATGACA TGAATTTTTT GCTTGCTCTA ATTGCACAAG GGCCTGTGAA GACTTACACT 
CACCGCCGTC TGAAGTTCCT CTCCTCCAAG TTCCAGGTCC ATCAGATGCT GAATGAGATG 
GACGAGCTAA AGGAGCTGAA GAACAACCCC CACCGGGACT TTTATAACTG CAGGAAGGTG 
GATACTCACA TCCACGCAGC TGCCTGCATG AACCAGAAGC ACCTGCTGCG CTTTATTAAG 
AAATCTTACC ATATTGATGC TGACAGAGTG GTCTACAGCA CCAAAGAGAA GAACCTGACC 
CTGAAGGAAC TTTTTGCTCA ATTAAATATG CATCCATATG ACCTGACTGT TGACTCTCTG 
GATGTTCATG CTGGACGGCA GACGTTCCAA CGCTTCGATA AGTTCAATGA CAAATACAAT 
CCGGTGGGTG CGAGTGAGCT TCGGGACCTC TACCTAAAAA CAGACAACTA CATTAACGGA 
GAGTATTTTG CCACTATCAT CAAGGAGGTG GGTGCAGACC TGGTGGACGC CAAGTATCAG 
CATGCGGAGC CCCGCTTGTC CATCTACGGT CGCAGTCCAG ATGAGTGGAG CAAACTCTCC 
TCTTGGTTTG TCGGCAACCG TATTTATTGC CCCAACATGA CATGGATGAT CCAAGTCCCC 
AGGATCTATG ATGTGTTCCG ATCCAAGAAT TTCCTGCCAC ACTTTGGAAA GATGCTGGAG 
AATATTTTCC TTCCAGTGTT TGAGGCCACC ATCAACCCCC AGACTCATCC AGACCTCAGT 
GTCTTCCTCA AGCATATCAC TGGCTTTGAC AGTGTGGATG ATGAGTCCAA ACACAGTGGT 
CACATGTTTT CCTCCAAGAG TCCCAAACCT GAGGAGTGGA CAATGGAAAA CAACCCGTCT 
TACACATATT ATGCCTACTA CATGTATGCA AACATCATGG TGCTCAACTG CCTGAGAAAG 
GAACGAGGCA TGAATACATT TTTGTTTCGC CCCCATTGTG GTGAGGCTGG GGCTCTCACT 
CACCTCATGA CAGCCTTTAT GATAGCGGAC AATATTTCGC ACGGCCTGAA CTTAAAGAAG 
AGTCCTGTGT TACAGTACCT ATTTTTCTTA GCCCAGATCC CCATTGCAAT GTCGCCATTG 
AGTAACAACA GCCTGTTCCT CGAATATGCA AAAAACCCTT TCTTAGATTT CCTCCAGAAA 
GGCCTCATGA TCTCGCTGTC GACCGATGAC CCGATGCAGT TCCATTTCAC CAAGGAGCCC 
CTGATGGAAG AGTACGCCAT CGCAGCCCAG GTCTTCAAGC TGAGCACTTG TGACATGTGT 
GAGGTGGCAA GGAACAGTGT CCTGCAGTGT GGAATTTCTC ATGAGGAAAA AGCAAAGTTT 
CTGGGCAACA ATTACCTTGA GGAAGGTCCT GTTGGAAATG ACATCCGAAG GACAAATGTG 
GCTCAGATTC GCATGGCCTA TCGTTATGAA ACTTGGTGTT ATGAACTCAA TTTGATTGCT 
GAGGGCCTTA AATCAACAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620231.1
CDS	12..2255
Translation	MPLFKLTGQGKQIDDAMRSFAEKVFASEVKDEGGRHEISPFDVDEICPISLREMQAHIFHMENLSMSMDGRRKRRFQGRKTVNLSIPQSETSSTKLSHIEEFISSSPTYESVPDFQRVQITGDYASGVTVEDFEVVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEALVAIESFYPVFTPPPKKGEDPFRREDLPANLGYHLKMKGGVIYIYPDEAAASRDEPKPYPYPNLDDFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYHIDADRVVYSTKEKNLTLKELFAQLNMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVDAKYQHAEPRLSIYGRSPDEWSKLSSWFVGNRIYCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFLPVFEATINPQTHPDLSVFLKHITGFDSVDDESKHSGHMFSSKSPKPEEWTMENNPSYTYYAYYMYANIMVLNCLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADNISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKAKFLGNNYLEEGPVGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKSTE

Target ORF information:

RefSeq Version	NM_138876.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenosine monophosphate deaminase 1 (Ampd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138876.1

ORF Insert Sequence:

ATGCCTCTGT TCAAACTTAC AGGTCAAGGA AAACAAATTG ATGATGCAAT GCGTAGCTTT 
GCTGAAAAAG TATTTGCCTC AGAAGTCAAA GATGAGGGAG GTCGGCACGA GATCTCCCCC 
TTCGACGTGG ATGAGATCTG CCCAATTTCC CTTCGTGAGA TGCAGGCCCA CATATTCCAC 
ATGGAGAACC TGTCCATGTC CATGGATGGC AGGAGGAAAA GGCGCTTCCA AGGACGGAAG 
ACTGTTAATT TGTCCATTCC GCAAAGTGAA ACGTCTTCTA CCAAACTGTC CCACATTGAA 
GAATTTATTT CTTCATCCCC GACCTATGAG AGTGTGCCTG ACTTCCAGAG GGTGCAGATC 
ACTGGTGACT ATGCCTCTGG GGTAACTGTT GAAGACTTTG AGGTGGTTTG TAAAGGTCTC 
TATCGGGCTT TGTGTATACG AGAGAAATAC ATGCAGAAGT CATTCCAGAG GTTCCCCAAG 
ACCCCCTCCA AGTACCTGAG GAACATCGAC GGCGAAGCTT TGGTAGCAAT CGAAAGCTTC 
TATCCAGTAT TTACCCCTCC TCCGAAGAAG GGAGAAGACC CCTTTCGCAG AGAAGACCTT 
CCCGCAAACC TGGGCTATCA CCTCAAGATG AAGGGTGGTG TGATTTACAT CTACCCTGAT 
GAAGCAGCAG CCAGCAGAGA TGAGCCCAAG CCCTACCCTT ACCCAAATCT GGATGACTTC 
CTGGATGACA TGAATTTTTT GCTTGCTCTA ATTGCACAAG GGCCTGTGAA GACTTACACT 
CACCGCCGTC TGAAGTTCCT CTCCTCCAAG TTCCAGGTCC ATCAGATGCT GAATGAGATG 
GACGAGCTAA AGGAGCTGAA GAACAACCCC CACCGGGACT TTTATAACTG CAGGAAGGTG 
GATACTCACA TCCACGCAGC TGCCTGCATG AACCAGAAGC ACCTGCTGCG CTTTATTAAG 
AAATCTTACC ATATTGATGC TGACAGAGTG GTCTACAGCA CCAAAGAGAA GAACCTGACC 
CTGAAGGAAC TTTTTGCTCA ATTAAATATG CATCCATATG ACCTGACTGT TGACTCTCTG 
GATGTTCATG CTGGACGGCA GACGTTCCAA CGCTTCGATA AGTTCAATGA CAAATACAAT 
CCGGTGGGTG CGAGTGAGCT TCGGGACCTC TACCTAAAAA CAGACAACTA CATTAACGGA 
GAGTATTTTG CCACTATCAT CAAGGAGGTG GGTGCAGACC TGGTGGACGC CAAGTATCAG 
CATGCGGAGC CCCGCTTGTC CATCTACGGT CGCAGTCCAG ATGAGTGGAG CAAACTCTCC 
TCTTGGTTTG TCGGCAACCG TATTTATTGC CCCAACATGA CATGGATGAT CCAAGTCCCC 
AGGATCTATG ATGTGTTCCG ATCCAAGAAT TTCCTGCCAC ACTTTGGAAA GATGCTGGAG 
AATATTTTCC TTCCAGTGTT TGAGGCCACC ATCAACCCCC AGACTCATCC AGACCTCAGT 
GTCTTCCTCA AGCATATCAC TGGCTTTGAC AGTGTGGATG ATGAGTCCAA ACACAGTGGT 
CACATGTTTT CCTCCAAGAG TCCCAAACCT GAGGAGTGGA CAATGGAAAA CAACCCGTCT 
TACACATATT ATGCCTACTA CATGTATGCA AACATCATGG TGCTCAACTG CCTGAGAAAG 
GAACGAGGCA TGAATACATT TTTGTTTCGC CCCCATTGTG GTGAGGCTGG GGCTCTCACT 
CACCTCATGA CAGCCTTTAT GATAGCGGAC AATATTTCGC ACGGCCTGAA CTTAAAGAAG 
AGTCCTGTGT TACAGTACCT ATTTTTCTTA GCCCAGATCC CCATTGCAAT GTCGCCATTG 
AGTAACAACA GCCTGTTCCT CGAATATGCA AAAAACCCTT TCTTAGATTT CCTCCAGAAA 
GGCCTCATGA TCTCGCTGTC GACCGATGAC CCGATGCAGT TCCATTTCAC CAAGGAGCCC 
CTGATGGAAG AGTACGCCAT CGCAGCCCAG GTCTTCAAGC TGAGCACTTG TGACATGTGT 
GAGGTGGCAA GGAACAGTGT CCTGCAGTGT GGAATTTCTC ATGAGGAAAA AGCAAAGTTT 
CTGGGCAACA ATTACCTTGA GGAAGGTCCT GTTGGAAATG ACATCCGAAG GACAAATGTG 
GCTCAGATTC GCATGGCCTA TCGTTATGAA ACTTGGTGTT ATGAACTCAA TTTGATTGCT 
GAGGGCCTTA AATCAACAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ampd1 ( XM_006233060.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006233122.1 Rattus norvegicus adenosine monophosphate deaminase 1 (Ampd1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa25125
Clone ID Related Accession (Same CDS sequence)	XM_006233060.3
Accession Version	XM_006233060.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2232bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	AMP deaminase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233060.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTCTGT TCAAACTTAC AGAAATTGAT GATGCAATGC GTAGCTTTGC TGAAAAAGTA 
TTTGCCTCAG AAGTCAAAGA TGAGGGAGGT CGGCACGAGA TCTCCCCCTT CGACGTGGAT 
GAGATCTGCC CAATTTCCCT TCGTGAGATG CAGGCCCACA TATTCCACAT GGAGAACCTG 
TCCATGTCCA TGGATGGCAG GAGGAAAAGG CGCTTCCAAG GACGGAAGAC TGTTAATTTG 
TCCATTCCGC AAAGTGAAAC GTCTTCTACC AAACTGTCCC ACATTGAAGA ATTTATTTCT 
TCATCCCCGA CCTATGAGAG TGTGCCTGAC TTCCAGAGGG TGCAGATCAC TGGTGACTAT 
GCCTCTGGGG TAACTGTTGA AGACTTTGAG GTGGTTTGTA AAGGTCTCTA TCGGGCTTTG 
TGTATACGAG AGAAATACAT GCAGAAGTCA TTCCAGAGGT TCCCCAAGAC CCCCTCCAAG 
TACCTGAGGA ACATCGACGG CGAAGCTTTG GTAGCAATCG AAAGCTTCTA TCCAGTATTT 
ACCCCTCCTC CGAAGAAGGG AGAAGACCCC TTTCGCAGAG AAGACCTTCC CGCAAACCTG 
GGCTATCACC TCAAGATGAA GGGTGGTGTG ATTTACATCT ACCCTGATGA AGCAGCAGCC 
AGCAGAGATG AGCCCAAGCC CTACCCTTAC CCAAATCTGG ATGACTTCCT GGATGACATG 
AATTTTTTGC TTGCTCTAAT TGCACAAGGG CCTGTGAAGA CTTACACTCA CCGCCGTCTG 
AAGTTCCTCT CCTCCAAGTT CCAGGTCCAT CAGATGCTGA ATGAGATGGA CGAGCTAAAG 
GAGCTGAAGA ACAACCCCCA CCGGGACTTT TATAACTGCA GGAAGGTGGA TACTCACATC 
CACGCAGCTG CCTGCATGAA CCAGAAGCAC CTGCTGCGCT TTATTAAGAA ATCTTACCAT 
ATTGATGCTG ACAGAGTGGT CTACAGCACC AAAGAGAAGA ACCTGACCCT GAAGGAACTT 
TTTGCTCAAT TAAATATGCA TCCATATGAC CTGACTGTTG ACTCTCTGGA TGTTCATGCT 
GGACGGCAGA CGTTCCAACG CTTCGATAAG TTCAATGACA AATACAATCC GGTGGGTGCG 
AGTGAGCTTC GGGACCTCTA CCTAAAAACA GACAACTACA TTAACGGAGA GTATTTTGCC 
ACTATCATCA AGGAGGTGGG TGCAGACCTG GTGGACGCCA AGTATCAGCA TGCGGAGCCC 
CGCTTGTCCA TCTACGGTCG CAGTCCAGAT GAGTGGAGCA AACTCTCCTC TTGGTTTGTC 
GGCAACCGTA TTTATTGCCC CAACATGACA TGGATGATCC AAGTCCCCAG GATCTATGAT 
GTGTTCCGAT CCAAGAATTT CCTGCCACAC TTTGGAAAGA TGCTGGAGAA TATTTTCCTT 
CCAGTGTTTG AGGCCACCAT CAACCCCCAG ACTCATCCAG ACCTCAGTGT CTTCCTCAAG 
CATATCACTG GCTTTGACAG TGTGGATGAT GAGTCCAAAC ACAGTGGTCA CATGTTTTCC 
TCCAAGAGTC CCAAACCTGA GGAGTGGACA ATGGAAAACA ACCCGTCTTA CACATATTAT 
GCCTACTACA TGTATGCAAA CATCATGGTG CTCAACTGCC TGAGAAAGGA ACGAGGCATG 
AATACATTTT TGTTTCGCCC CCATTGTGGT GAGGCTGGGG CTCTCACTCA CCTCATGACA 
GCCTTTATGA TAGCGGACAA TATTTCGCAC GGCCTGAACT TAAAGAAGAG TCCTGTGTTA 
CAGTACCTAT TTTTCTTAGC CCAGATCCCC ATTGCAATGT CGCCATTGAG TAACAACAGC 
CTGTTCCTCG AATATGCAAA AAACCCTTTC TTAGATTTCC TCCAGAAAGG CCTCATGATC 
TCGCTGTCGA CCGATGACCC GATGCAGTTC CATTTCACCA AGGAGCCCCT GATGGAAGAG 
TACGCCATCG CAGCCCAGGT CTTCAAGCTG AGCACTTGTG ACATGTGTGA GGTGGCAAGG 
AACAGTGTCC TGCAGTGTGG AATTTCTCAT GAGGAAAAAG CAAAGTTTCT GGGCAACAAT 
TACCTTGAGG AAGGTCCTGT TGGAAATGAC ATCCGAAGGA CAAATGTGGC TCAGATTCGC 
ATGGCCTATC GTTATGAAAC TTGGTGTTAT GAACTCAATT TGATTGCTGA GGGCCTTAAA 
TCAACAGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006233122.1
CDS	102..2333
Translation	MPLFKLTEIDDAMRSFAEKVFASEVKDEGGRHEISPFDVDEICPISLREMQAHIFHMENLSMSMDGRRKRRFQGRKTVNLSIPQSETSSTKLSHIEEFISSSPTYESVPDFQRVQITGDYASGVTVEDFEVVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEALVAIESFYPVFTPPPKKGEDPFRREDLPANLGYHLKMKGGVIYIYPDEAAASRDEPKPYPYPNLDDFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYHIDADRVVYSTKEKNLTLKELFAQLNMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVDAKYQHAEPRLSIYGRSPDEWSKLSSWFVGNRIYCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFLPVFEATINPQTHPDLSVFLKHITGFDSVDDESKHSGHMFSSKSPKPEEWTMENNPSYTYYAYYMYANIMVLNCLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADNISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKAKFLGNNYLEEGPVGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKSTE

Target ORF information:

RefSeq Version	XM_006233060.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus adenosine monophosphate deaminase 1 (Ampd1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006233060.3

ORF Insert Sequence:

ATGCCTCTGT TCAAACTTAC AGAAATTGAT GATGCAATGC GTAGCTTTGC TGAAAAAGTA 
TTTGCCTCAG AAGTCAAAGA TGAGGGAGGT CGGCACGAGA TCTCCCCCTT CGACGTGGAT 
GAGATCTGCC CAATTTCCCT TCGTGAGATG CAGGCCCACA TATTCCACAT GGAGAACCTG 
TCCATGTCCA TGGATGGCAG GAGGAAAAGG CGCTTCCAAG GACGGAAGAC TGTTAATTTG 
TCCATTCCGC AAAGTGAAAC GTCTTCTACC AAACTGTCCC ACATTGAAGA ATTTATTTCT 
TCATCCCCGA CCTATGAGAG TGTGCCTGAC TTCCAGAGGG TGCAGATCAC TGGTGACTAT 
GCCTCTGGGG TAACTGTTGA AGACTTTGAG GTGGTTTGTA AAGGTCTCTA TCGGGCTTTG 
TGTATACGAG AGAAATACAT GCAGAAGTCA TTCCAGAGGT TCCCCAAGAC CCCCTCCAAG 
TACCTGAGGA ACATCGACGG CGAAGCTTTG GTAGCAATCG AAAGCTTCTA TCCAGTATTT 
ACCCCTCCTC CGAAGAAGGG AGAAGACCCC TTTCGCAGAG AAGACCTTCC CGCAAACCTG 
GGCTATCACC TCAAGATGAA GGGTGGTGTG ATTTACATCT ACCCTGATGA AGCAGCAGCC 
AGCAGAGATG AGCCCAAGCC CTACCCTTAC CCAAATCTGG ATGACTTCCT GGATGACATG 
AATTTTTTGC TTGCTCTAAT TGCACAAGGG CCTGTGAAGA CTTACACTCA CCGCCGTCTG 
AAGTTCCTCT CCTCCAAGTT CCAGGTCCAT CAGATGCTGA ATGAGATGGA CGAGCTAAAG 
GAGCTGAAGA ACAACCCCCA CCGGGACTTT TATAACTGCA GGAAGGTGGA TACTCACATC 
CACGCAGCTG CCTGCATGAA CCAGAAGCAC CTGCTGCGCT TTATTAAGAA ATCTTACCAT 
ATTGATGCTG ACAGAGTGGT CTACAGCACC AAAGAGAAGA ACCTGACCCT GAAGGAACTT 
TTTGCTCAAT TAAATATGCA TCCATATGAC CTGACTGTTG ACTCTCTGGA TGTTCATGCT 
GGACGGCAGA CGTTCCAACG CTTCGATAAG TTCAATGACA AATACAATCC GGTGGGTGCG 
AGTGAGCTTC GGGACCTCTA CCTAAAAACA GACAACTACA TTAACGGAGA GTATTTTGCC 
ACTATCATCA AGGAGGTGGG TGCAGACCTG GTGGACGCCA AGTATCAGCA TGCGGAGCCC 
CGCTTGTCCA TCTACGGTCG CAGTCCAGAT GAGTGGAGCA AACTCTCCTC TTGGTTTGTC 
GGCAACCGTA TTTATTGCCC CAACATGACA TGGATGATCC AAGTCCCCAG GATCTATGAT 
GTGTTCCGAT CCAAGAATTT CCTGCCACAC TTTGGAAAGA TGCTGGAGAA TATTTTCCTT 
CCAGTGTTTG AGGCCACCAT CAACCCCCAG ACTCATCCAG ACCTCAGTGT CTTCCTCAAG 
CATATCACTG GCTTTGACAG TGTGGATGAT GAGTCCAAAC ACAGTGGTCA CATGTTTTCC 
TCCAAGAGTC CCAAACCTGA GGAGTGGACA ATGGAAAACA ACCCGTCTTA CACATATTAT 
GCCTACTACA TGTATGCAAA CATCATGGTG CTCAACTGCC TGAGAAAGGA ACGAGGCATG 
AATACATTTT TGTTTCGCCC CCATTGTGGT GAGGCTGGGG CTCTCACTCA CCTCATGACA 
GCCTTTATGA TAGCGGACAA TATTTCGCAC GGCCTGAACT TAAAGAAGAG TCCTGTGTTA 
CAGTACCTAT TTTTCTTAGC CCAGATCCCC ATTGCAATGT CGCCATTGAG TAACAACAGC 
CTGTTCCTCG AATATGCAAA AAACCCTTTC TTAGATTTCC TCCAGAAAGG CCTCATGATC 
TCGCTGTCGA CCGATGACCC GATGCAGTTC CATTTCACCA AGGAGCCCCT GATGGAAGAG 
TACGCCATCG CAGCCCAGGT CTTCAAGCTG AGCACTTGTG ACATGTGTGA GGTGGCAAGG 
AACAGTGTCC TGCAGTGTGG AATTTCTCAT GAGGAAAAAG CAAAGTTTCT GGGCAACAAT 
TACCTTGAGG AAGGTCCTGT TGGAAATGAC ATCCGAAGGA CAAATGTGGC TCAGATTCGC 
ATGGCCTATC GTTATGAAAC TTGGTGTTAT GAACTCAATT TGATTGCTGA GGGCCTTAAA 
TCAACAGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Variation in the gene for muscle-specific AMP deaminase is associated with insulin clearance, a highly heritable trait.
Diabetes54(4)1222-7(2005 Apr)
Goodarzi MO,Taylor KD,Guo X,Quiñones MJ,Cui J,Li X,Hang T,Yang H,Holmes E,Hsueh WA,Olefsky J,Rotter JI

High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Genome research14(4)750-7(2004 Apr)
Kwitek AE,Gullings-Handley J,Yu J,Carlos DC,Orlebeke K,Nie J,Eckert J,Lemke A,Andrae JW,Bromberg S,Pasko D,Chen D,Scheetz TE,Casavant TL,Soares MB,Sheffield VC,Tonellato PJ,Jacob HJ

Improved radiation hybrid map of rat chromosome 2: colocalization of the genes encoding corticotropin-releasing hormone and IL6-receptor with quantitative trait loci regulating the inflammatory response.
Cytogenetics and cell genetics92(1-2)130-3(2001)
Laes JF,Ravoet M,Quan X,Van Vooren P,Szpirer J,Szpirer C

Novel aspects of tetramer assembly and N-terminal domain structure and function are revealed by recombinant expression of human AMP deaminase isoforms.
The Journal of biological chemistry273(52)35118-25(1998 Dec)
Mahnke-Zizelman DK,Tullson PC,Sabina RL

Control of AMP deaminase 1 binding to myosin heavy chain.
The American journal of physiology275(3)C870-81(1998 09)
Hisatome I,Morisaki T,Kamma H,Sugama T,Morisaki H,Ohtahara A,Holmes EW

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Ampd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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