| Gene Symbol | Fgl1 |
| Entrez Gene ID | 246186 |
| Full Name | fibrinogen-like 1 |
| Synonyms | Frep1,Lfire1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | member of the fibrinogen family; appears to lack the platelet-binding and thrombin-sensitive sites, and cross-linking region, which are necessary for fibrin clot formation; protein may be liver-specific [RGD, Feb 2006]. |
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Fgl1 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Fgl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fgl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa02350 Clone ID Related Accession (Same CDS sequence) NM_172010.1 Accession Version NM_172010.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 804bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1576857600000 Organism Rattus norvegicus(Norway rat) Product fibrinogen-like protein 1 precursor Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF508020.1. ##Evidence-Data-START## Transcript exon combination :: AF508020.1, BC088107.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689598, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781ATGGGGGAGA TTCGCAGCTT TGTCCTCATC ACTGTTGCTC TGATTCTGGG CAAGGAGAGC
TGGGTCCTCG GAGATGAGAA CTGTTTGCAG GAGCAGGTGA GGCTCAGGGC TCAGGTGCGC
CAGCTTGAGA CCCGGGTCAA ACAACAACAG GTGGTGATTG CACAGCTCTT GCACGAGAAG
GAGGTCCAGT TCCTGGATAG AGGACAGGAG GACAGCTTCA TTGACCTTGG AGGCAAGAGG
CATTACGCAG ATTGTTCAGA GATTTACAAT GATGGATTTA AACATAGTGG GTTTTACAAA
ATCAAACCTC TTCAGAGTCT GGCAGAATTC TCTGTTTATT GTGATATGTC TGATGGAGGA
GGATGGACTG TAATTCAGAG ACGATCTGAC GGCAGTGAGA ACTTTAACAG GGGTTGGAAC
GACTATGAAA ATGGCTTTGG AAACTTTGTC CAAAGCAATG GTGAATACTG GCTGGGTAAC
AAAAACATTA ACTTGCTGAC TATGCAAGGA GACTACACTT TAAAAATCGA CCTGACAGAC
TTTGAGAAAA ACAGCCGCTT CGCACAATAC GAAAAATTTA AAGTTGGCGA TGAAAAGTCT
TTTTACGAAC TGAATATTGG AGAATATTCT GGCACCGCCG GAGACTCCCT GTCGGGAACA
TTTCACCCTG AAGTGCAGTG GTGGGCTAGT CACCAAACAA TGAAGTTCAG CACACGCGAC
AGAGACAACG ACAACTACAA CGGGAACTGT GCTGAGGAGG AACAGTCTGG CTGGTGGTTA
ACAGGTGTCA CTCTGCAAAC CTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_742007.1 CDS 100..903 Translation 
Target ORF information:
RefSeq Version NM_172010.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus fibrinogen-like 1 (Fgl1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_172010.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781ATGGGGGAGA TTCGCAGCTT TGTCCTCATC ACTGTTGCTC TGATTCTGGG CAAGGAGAGC
TGGGTCCTCG GAGATGAGAA CTGTTTGCAG GAGCAGGTGA GGCTCAGGGC TCAGGTGCGC
CAGCTTGAGA CCCGGGTCAA ACAACAACAG GTGGTGATTG CACAGCTCTT GCACGAGAAG
GAGGTCCAGT TCCTGGATAG AGGACAGGAG GACAGCTTCA TTGACCTTGG AGGCAAGAGG
CATTACGCAG ATTGTTCAGA GATTTACAAT GATGGATTTA AACATAGTGG GTTTTACAAA
ATCAAACCTC TTCAGAGTCT GGCAGAATTC TCTGTTTATT GTGATATGTC TGATGGAGGA
GGATGGACTG TAATTCAGAG ACGATCTGAC GGCAGTGAGA ACTTTAACAG GGGTTGGAAC
GACTATGAAA ATGGCTTTGG AAACTTTGTC CAAAGCAATG GTGAATACTG GCTGGGTAAC
AAAAACATTA ACTTGCTGAC TATGCAAGGA GACTACACTT TAAAAATCGA CCTGACAGAC
TTTGAGAAAA ACAGCCGCTT CGCACAATAC GAAAAATTTA AAGTTGGCGA TGAAAAGTCT
TTTTACGAAC TGAATATTGG AGAATATTCT GGCACCGCCG GAGACTCCCT GTCGGGAACA
TTTCACCCTG AAGTGCAGTG GTGGGCTAGT CACCAAACAA TGAAGTTCAG CACACGCGAC
AGAGACAACG ACAACTACAA CGGGAACTGT GCTGAGGAGG AACAGTCTGG CTGGTGGTTA
ACAGGTGTCA CTCTGCAAAC CTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3.
Cell176(1-2)334-347.e12(2019 01)
Wang J,Sanmamed MF,Datar I,Su TT,Ji L,Sun J,Chen L,Chen Y,Zhu G,Yin W,Zheng L,Zhou T,Badri T,Yao S,Zhu S,Boto A,Sznol M,Melero I,Vignali DAA,Schalper K,Chen L
Bone marrow-derived mesenchymal stem cells attenuate acute liver injury and regulate the expression of fibrinogen-like-protein 1 and signal transducer and activator of transcription 3.
Molecular medicine reports12(2)2089-97(2015 Aug)
Zou Z,Cai Y,Chen Y,Chen S,Liu L,Shen Z,Zhang S,Xu L,Chen Y
Targeted deletion of fibrinogen like protein 1 reveals a novel role in energy substrate utilization.
PloS one8(3)e58084(2013)
Demchev V,Malana G,Vangala D,Stoll J,Desai A,Kang HW,Li Y,Nayeb-Hashemi H,Niepel M,Cohen DE,Ukomadu C
Recombinant human hepassocin stimulates proliferation of hepatocytes in vivo and improves survival in rats with fulminant hepatic failure.
Gut59(6)817-26(2010 Jun)
Li CY,Cao CZ,Xu WX,Cao MM,Yang F,Dong L,Yu M,Zhan YQ,Gao YB,Li W,Wang ZD,Ge CH,Wang QM,Peng RY,Yang XM
Resveratrol improves health and survival of mice on a high-calorie diet.
Nature444(7117)337-42(2006 Nov)
Baur JA,Pearson KJ,Price NL,Jamieson HA,Lerin C,Kalra A,Prabhu VV,Allard JS,Lopez-Lluch G,Lewis K,Pistell PJ,Poosala S,Becker KG,Boss O,Gwinn D,Wang M,Ramaswamy S,Fishbein KW,Spencer RG,Lakatta EG,Le Couteur D,Shaw RJ,Navas P,Puigserver P,Ingram DK,de Cabo R,Sinclair DA
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