| Gene Symbol | Myl3 |
| Entrez Gene ID | 24585 |
| Full Name | myosin light chain 3 |
| Synonyms | MLClV,Mylc1v,rVMLC1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | predominant myosin light chain in cardiac tissue [RGD, Feb 2006]. |
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Myl3 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Myl3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Myl3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa00444 Clone ID Related Accession (Same CDS sequence) NM_012606.2 , XM_006243917.3 Accession Version NM_012606.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 603bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577116800000 Organism Rattus norvegicus(Norway rat) Product myosin light chain 3 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081832.1. On Jan 26, 2008 this sequence version replaced NM_012606.1. ##Evidence-Data-START## Transcript exon combination :: BC081832.1, FQ216255.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689596, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601ATGGCCCCCA AAAAGCCAGA GCCCAAGAAG GACGATGCCA AAACCGCTGC CCCCAAAGCA
GCTCCGGCCC CTGCGGCTGC ACCTGCGGCT GCACCTGAGC CCGAACGCCC TAAGGAAGCA
GAGTTTGATG CCTCCAAGAT TAAGATTGAG TTCACGCCTG AACAGATTGA AGAGTTCAAG
GAGGCCTTCC AACTGTTTGA CCGCACACCT AAGGGCGAGA TGAAGATCAC GTACGGGCAG
TGTGGGGATG TCCTGCGGGC TCTGGGACAG AATCCTACCC AGGCAGAGGT GCTCCGCGTC
TTGGGGAAGC CCAAACAGGA AGAGCTCAAC TCCAAGATGA TGGATTTTGA AACATTCCTG
CCCATGCTGC AGCACATCTC CAAGAACAAA GACACGGGCA CATATGAGGA CTTCGTGGAG
GGGCTGCGGG TCTTCGACAA GGAGGGCAAC GGAACTGTTA TGGGTGCAGA GCTCCGTCAT
GTGCTGGCCA CGCTGGGTGA GAGGCTGACA GAAGACGAGG TAGAGAAACT GATGGCTGGT
CAAGAAGACT CCAATGGCTG CATCAACTAT GAAGCATTTG TGAAGCACAT CATGGCCAGC
TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_036738.1 CDS 53..655 Translation 
Target ORF information:
RefSeq Version NM_012606.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus myosin light chain 3 (Myl3), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_012606.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601ATGGCCCCCA AAAAGCCAGA GCCCAAGAAG GACGATGCCA AAACCGCTGC CCCCAAAGCA
GCTCCGGCCC CTGCGGCTGC ACCTGCGGCT GCACCTGAGC CCGAACGCCC TAAGGAAGCA
GAGTTTGATG CCTCCAAGAT TAAGATTGAG TTCACGCCTG AACAGATTGA AGAGTTCAAG
GAGGCCTTCC AACTGTTTGA CCGCACACCT AAGGGCGAGA TGAAGATCAC GTACGGGCAG
TGTGGGGATG TCCTGCGGGC TCTGGGACAG AATCCTACCC AGGCAGAGGT GCTCCGCGTC
TTGGGGAAGC CCAAACAGGA AGAGCTCAAC TCCAAGATGA TGGATTTTGA AACATTCCTG
CCCATGCTGC AGCACATCTC CAAGAACAAA GACACGGGCA CATATGAGGA CTTCGTGGAG
GGGCTGCGGG TCTTCGACAA GGAGGGCAAC GGAACTGTTA TGGGTGCAGA GCTCCGTCAT
GTGCTGGCCA CGCTGGGTGA GAGGCTGACA GAAGACGAGG TAGAGAAACT GATGGCTGGT
CAAGAAGACT CCAATGGCTG CATCAACTAT GAAGCATTTG TGAAGCACAT CATGGCCAGC
TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID ORa00444 Clone ID Related Accession (Same CDS sequence) NM_012606.2 , XM_006243917.3 Accession Version XM_006243917.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 603bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1469376000000 Organism Rattus norvegicus(Norway rat) Product myosin light chain 3 isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006243917.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
61
121
181
241
301
361
421
481
541
601ATGGCCCCCA AAAAGCCAGA GCCCAAGAAG GACGATGCCA AAACCGCTGC CCCCAAAGCA
GCTCCGGCCC CTGCGGCTGC ACCTGCGGCT GCACCTGAGC CCGAACGCCC TAAGGAAGCA
GAGTTTGATG CCTCCAAGAT TAAGATTGAG TTCACGCCTG AACAGATTGA AGAGTTCAAG
GAGGCCTTCC AACTGTTTGA CCGCACACCT AAGGGCGAGA TGAAGATCAC GTACGGGCAG
TGTGGGGATG TCCTGCGGGC TCTGGGACAG AATCCTACCC AGGCAGAGGT GCTCCGCGTC
TTGGGGAAGC CCAAACAGGA AGAGCTCAAC TCCAAGATGA TGGATTTTGA AACATTCCTG
CCCATGCTGC AGCACATCTC CAAGAACAAA GACACGGGCA CATATGAGGA CTTCGTGGAG
GGGCTGCGGG TCTTCGACAA GGAGGGCAAC GGAACTGTTA TGGGTGCAGA GCTCCGTCAT
GTGCTGGCCA CGCTGGGTGA GAGGCTGACA GAAGACGAGG TAGAGAAACT GATGGCTGGT
CAAGAAGACT CCAATGGCTG CATCAACTAT GAAGCATTTG TGAAGCACAT CATGGCCAGC
TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_006243979.3 CDS 76..678 Translation
Target ORF information:
RefSeq Version XM_006243917.3 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus myosin light chain 3 (Myl3), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_006243917.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601ATGGCCCCCA AAAAGCCAGA GCCCAAGAAG GACGATGCCA AAACCGCTGC CCCCAAAGCA
GCTCCGGCCC CTGCGGCTGC ACCTGCGGCT GCACCTGAGC CCGAACGCCC TAAGGAAGCA
GAGTTTGATG CCTCCAAGAT TAAGATTGAG TTCACGCCTG AACAGATTGA AGAGTTCAAG
GAGGCCTTCC AACTGTTTGA CCGCACACCT AAGGGCGAGA TGAAGATCAC GTACGGGCAG
TGTGGGGATG TCCTGCGGGC TCTGGGACAG AATCCTACCC AGGCAGAGGT GCTCCGCGTC
TTGGGGAAGC CCAAACAGGA AGAGCTCAAC TCCAAGATGA TGGATTTTGA AACATTCCTG
CCCATGCTGC AGCACATCTC CAAGAACAAA GACACGGGCA CATATGAGGA CTTCGTGGAG
GGGCTGCGGG TCTTCGACAA GGAGGGCAAC GGAACTGTTA TGGGTGCAGA GCTCCGTCAT
GTGCTGGCCA CGCTGGGTGA GAGGCTGACA GAAGACGAGG TAGAGAAACT GATGGCTGGT
CAAGAAGACT CCAATGGCTG CATCAACTAT GAAGCATTTG TGAAGCACAT CATGGCCAGC
TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
The roles of myosin ATPase activity and myosin light chain relative content in the slowing of type IIB fibers with hindlimb unweighting in rats.
American journal of physiology. Cell physiology293(2)C723-8(2007 Aug)
Zhong S,Thompson LV
Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study.
Circulation113(23)2697-705(2006 Jun)
Morita H,Larson MG,Barr SC,Vasan RS,O'Donnell CJ,Hirschhorn JN,Levy D,Corey D,Seidman CE,Seidman JG,Benjamin EJ
Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology20(7)865-73(2006 May)
Haase H,Dobbernack G,Tünnemann G,Karczewski P,Cardoso C,Petzhold D,Schlegel WP,Lutter S,Pierschalek P,Behlke J,Morano I
Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin-myosin interaction.
Cardiovascular research60(3)580-8(2003 Dec)
Yamashita H,Sugiura S,Fujita H,Yasuda Si,Nagai R,Saeki Y,Sunagawa K,Sugi H
Myosin light chain mutations in familial hypertrophic cardiomyopathy: phenotypic presentation and frequency in Danish and South African populations.
Journal of medical genetics38(12)E43(2001 Dec)
Andersen PS,Havndrup O,Bundgaard H,Moolman-Smook JC,Larsen LA,Mogensen J,Brink PA,Børglum AD,Corfield VA,Kjeldsen K,Vuust J,Christiansen M
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