Grin3a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Grin3a
Entrez Gene ID	191573
Full Name	glutamate ionotropic receptor NMDA type subunit 3A
Synonyms	GluN3A,NR3,chi-1
General protein information	Preferred Names glutamate ionotropic receptor NMDA type subunit 3A Names glutamate receptor ionotropic, NMDA 3A N-methyl-D-aspartate receptor subtype 3A NMDAR-L NMDAR-L1 NMDAR3A NR3 chi-1 NR3A glutamate [NMDA] receptor subunit 3A glutamate receptor chi-1 glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q22
Summary	glutamate receptor subunit involved in neuronal signaling [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_138546.2	NP_612555.1	glutamate receptor ionotropic, NMDA 3A isoform 1 precursor
NM_001198583.2	NP_001185512.1	glutamate receptor ionotropic, NMDA 3A isoform 2 precursor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	GRIN3A	XP_001107918.2
Mus musculus (house mouse)	Grin3a	NP_001028523.1
Rattus norvegicus (Norway rat)	Grin3a	NP_001185512.1
Gallus gallus (chicken)	GRIN3A	XP_001232182.2
Bos taurus (cattle)	GRIN3A	NP_001178464.1
Pan troglodytes (chimpanzee)	GRIN3A	XP_003312259.1
Canis lupus familiaris (dog)	GRIN3A	XP_532019.2
Homo sapiens (human)	GRIN3A	NP_597702.2
Xenopus tropicalis (tropical clawed frog)	grin3a	XP_002938585.2

Gene Ontology
Bibliography

Related articles in PubMed

Glycine induces bidirectional modifications in N-methyl-D-aspartate receptor-mediated synaptic responses in hippocampal CA1 neurons.
Zhang XY, Ji F, Wang N, Chen LL, Tian T, Lu W
The Journal of biological chemistry289(45)31200-11(2014 Nov)

Synapse-specific control of experience-dependent plasticity by presynaptic NMDA receptors.
Larsen RS, Smith IT, Miriyala J, Han JE, Corlew RJ, Smith SL, Philpot BD
Neuron83(4)879-93(2014 Aug)

Gestational chronodisruption impairs hippocampal expression of NMDA receptor subunits Grin1b/Grin3a and spatial memory in the adult offspring.
Vilches N, Spichiger C, Mendez N, Abarzua-Catalan L, Galdames HA, Hazlerigg DG, Richter HG, Torres-Farfan C
PloS one9(3)e91313(2014)

GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling.
Fiuza M, González-González I, Pérez-Otaño I
Proceedings of the National Academy of Sciences of the United States of America110(51)20807-12(2013 Dec)

Expression of cocaine-evoked synaptic plasticity by GluN3A-containing NMDA receptors.
Yuan T, Mameli M, O'Connor EC, O' Connor EC, Dey PN, Verpelli C, Sala C, Perez-Otano I, Lüscher C, Bellone C
Neuron80(4)1025-38(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Grin3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grin3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa44362	NM_001198583.2 Latest version!	Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3A (Grin3a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
ORa44363	NM_138546.2 Latest version!	Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3A (Grin3a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Grin3a ( NM_001198583.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001185512.1 Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3A (Grin3a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa44362
Clone ID Related Accession (Same CDS sequence)	NM_001198583.2
Accession Version	NM_001198583.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Rattus norvegicus(Norway rat)
Product	glutamate receptor ionotropic, NMDA 3A isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U29873.1 and BI294379.1. On Oct 9, 2014 this sequence version replaced NM_001198583.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U29873.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGGAGAC TGAGTTTGTG GTGGCTGCTG AGCAGGGTCT GTCTGCTGCT GCCGCCGCCC 
TGCGCACTGG TGCTGGCCGG GGTGCCCAGC TCCTCCTCGC ACCCGCAACC CTGCCAGATC 
CTCAAGCGCA TCGGACACGC GGTGAGGGTG GGCGCGGTGC ACTTGCAACC CTGGACCACG 
GCCCCACGCG CAGCCAGTCG CGCTCAGGAA GGCGGCAGGG CGGGTGCCCA GAGGGATGAT 
CCAGAGTCCG GGACGTGGCG GCCACCGGCG CCCTCGCAAG GCGCACGCTG GTTGGGGAGC 
GCCCTGCATG GCCGGGGTCC ACCCGGCTCC CGAAAGCTCG GGGAGGGCGC GGGGGCCGAG 
ACCCTGTGGC CGCGGGATGC CCTACTGTTC GCTGTGGAAA ACTTGAACCG TGTGGAAGGG 
CTCCTACCCT ACAACCTGTC TTTGGAAGTA GTGATGGCCA TTGAGGCGGG CCTGGGCGAT 
CTGCCGCTTA TGCCCTTCTC TTCCCCAAGC TCACCGTGGA GCAGTGACCC TTTCTCCTTT 
CTGCAGAGCG TGTGCCACAC CGTAGTGGTA CAAGGGGTGT CGGCGCTGCT GGCCTTCCCC 
CAGAGCCAGG GCGAAATGAT GGAGCTGGAC TTGGTCAGCT CTGTCCTGCA CATCCCAGTG 
CTCAGCATAG TGCGCCACGA GTTTCCGCGG GAGAGTCAGA ATCCCCTGCA CCTACAGCTG 
AGTTTAGAAA ACTCACTAAG TTCTGATGCT GATGTCACTG TCTCAATCCT GACCATGAAC 
AACTGGTACA ATTTTAGCTT GTTGCTCTGC CAGGAAGACT GGAATATCAC GGACTTCCTC 
CTCCTTACGG AGAATAACTC CAAGTTCCAC CTCGAGTCTG TTATCAACAT CACTGCTAAT 
CTGTCCTCCA CAAAGGACCT TCTAAGTTTC CTGCAGGTCC AGATGGACAA CATTAGGAAC 
AGCACACCCA CAATGGTGAT GTTTGGCTGT GACATGGACA GTATCCGGCA GATATTTGAA 
ATGTCCACAC AGTTTGGGCT ATCACCTCCT GAACTTCACT GGGTTTTAGG AGACTCCCAG 
AATGTGGAGG AACTGAGGAC AGAAGGCCTG CCCTTAGGGC TCATTGCTCA TGGAAAAACC 
ACACAATCTG TCTTTGAGTA CTACGTTCAG GATGCCATGG AGTTGGTTGC AAGAGCTGTA 
GCCACAGCCA CCATGATCCA GCCAGAGCTT GCTCTCCTTC CCAGCACAAT GAACTGCATG 
GATGTGAAAA CCACAAATCT CACTTCTGGA CAGTATTTAT CAAGGTTTTT AGCCAACACC 
ACTTTCAGAG GTCTCAGTGG TTCCATCAAA GTAAAGGGCT CCACCATCAT CAGCTCAGAG 
AACAACTTTT TCATCTGGAA CTTGCAGCAC GACCCTATGG GAAAGCCAAT GTGGACTCGC 
CTGGGCAGCT GGCAAGGAGG AAGGATAGTC ATGGACTCTG GAATATGGCC AGAGCAGGCC 
CAGAGGCACA AAACCCACTT CCAGCACCCA AACAAGTTAC ACTTGAGAGT GGTGACATTG 
ATTGAACACC CATTTGTTTT CACGAGAGAA GTAGACGATG AAGGCTTATG CCCTGCTGGA 
CAGCTCTGTC TAGACCCTAT GACTAACGAC TCTTCCATGC TGGATCGTCT GTTTAGCAGC 
CTGCATAGCA GTAATGACAC AGTGCCAATC AAGTTCAAGA AGTGCTGTTA TGGGTACTGC 
ATCGATCTCC TGGAGCAGCT AGCAGAAGAC ATGAACTTTG ACTTTGACCT CTACATTGTA 
GGGGATGGAA AGTACGGAGC TTGGAAAAAT GGTCACTGGA CTGGGCTGGT TGGTGATCTC 
CTGAGTGGGA CAGCCAACAT GGCGGTCACT TCTTTCAGCA TCAATACCGC ACGAAGCCAG 
GTGATAGATT TCACCAGCCC TTTCTTCTCA ACCAGTTTGG GGATCTTAGT GAGGACTCGA 
GACACAGCAG CTCCAATTGG AGCCTTCATG TGGCCACTCC ACTGGACCAT GTGGCTGGGA 
ATTTTCGTGG CTCTCCATAT CACTGCCATT TTTCTCACTC TGTATGAATG GAAGAGCCCC 
TTTGGTATGA CCCCTAAGGG GAGGAACAGA AACAAAGTCT TCTCCTTCTC CTCAGCTTTG 
AATGTCTGCT ATGCCCTTCT GTTTGGCAGA ACAGCAGCCA TCAAACCCCC AAAATGCTGG 
ACTGGAAGGT TTCTGATGAA TCTTTGGGCC ATTTTCTGTA TGTTTTGCCT TTCTACATAC 
ACAGCGAACT TGGCTGCTGT CATGGTAGGT GAGAAGATCT ATGAAGAGCT TTCTGGAATT 
CATGACCCTA AGCTTCATCA TCCTTCTCAA GGCTTCCGCT TTGGAACTGT CCGGGAAAGC 
AGTGCTGAAG ACTATGTGCG CCAGAGCTTC CCAGAGATGC ATGAGTACAT GAGAAGGTAC 
AACGTGCCAG CCACCCCTGA TGGAGTGCAG TATCTGAAGA ATGATCCAGA GAAACTAGAC 
GCCTTCATCA TGGACAAAGC CCTTCTGGAT TATGAAGTGT CAATAGATGC TGACTGCAAG 
CTTCTGACCG TAGGAAAGCC ATTTGCCATC GAAGGATATG GCATTGGTCT CCCTCCAAAC 
TCTCCATTGA CCTCTAATAT ATCTGAGCTC ATCAGTCAGT ACAAGTCTCA CGGGTTTATG 
GATGTGCTCC ATGACAAGTG GTACAAGGTG GTTCCCTGCG GAAAGAGAAG CTTTGCCGTC 
ACTGAGACTT TGCAAATGGG CATCAAGCAC TTCTCTGGAC TCTTCGTGCT GTTGTGCATA 
GGATTTGGTC TCTCCATCCT GACCACCATT GGTGAACACA TAGTGCACAG ACTGCTGTTA 
CCACGCATCA AAAACAAATC CAAGCTGCAG TACTGGCTGC ACACGAGTCA GAGGTTTCAC 
AGAGCATTAA ACACGTCATT CGTAGAAGAA AAGCAGCCAC GTTCCAAGAC AAAACGTGTG 
GAGAAGAGGT CCAACCTGGG ACCCCAGCAG CTCATGGTAT GGAATACTTC CAATCTGAGT 
CATGACAACC AACGAAAATA CATCTTTAAT GACGAGGAAG GACAAAACCA GCTGGGTACC 
CAGGCCCACC AGGACATCCC TCTCCCTCAG AGGAGAAGAG AGCTCCCTGC CTCACTGACC 
ACCAATGGGA AAGCAGACTC CCTCAATGTA ACTCGGAGCT CCGTGATTCA GGAACTCTCT 
GAGTTGGAGA AGCAGATCCA AGTGATCCGC CAGGAGCTGC AGTTGGCTGT AAGCAGGAAG 
ACAGAGCTGG AGGAGTATCA AAAGACAAAT CGGACTTGTG AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185512.1
CDS	474..3821
Translation	MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITANLSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLTTNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES

Target ORF information:

RefSeq Version	NM_001198583.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3A (Grin3a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198583.2

ORF Insert Sequence:

ATGAGGAGAC TGAGTTTGTG GTGGCTGCTG AGCAGGGTCT GTCTGCTGCT GCCGCCGCCC 
TGCGCACTGG TGCTGGCCGG GGTGCCCAGC TCCTCCTCGC ACCCGCAACC CTGCCAGATC 
CTCAAGCGCA TCGGACACGC GGTGAGGGTG GGCGCGGTGC ACTTGCAACC CTGGACCACG 
GCCCCACGCG CAGCCAGTCG CGCTCAGGAA GGCGGCAGGG CGGGTGCCCA GAGGGATGAT 
CCAGAGTCCG GGACGTGGCG GCCACCGGCG CCCTCGCAAG GCGCACGCTG GTTGGGGAGC 
GCCCTGCATG GCCGGGGTCC ACCCGGCTCC CGAAAGCTCG GGGAGGGCGC GGGGGCCGAG 
ACCCTGTGGC CGCGGGATGC CCTACTGTTC GCTGTGGAAA ACTTGAACCG TGTGGAAGGG 
CTCCTACCCT ACAACCTGTC TTTGGAAGTA GTGATGGCCA TTGAGGCGGG CCTGGGCGAT 
CTGCCGCTTA TGCCCTTCTC TTCCCCAAGC TCACCGTGGA GCAGTGACCC TTTCTCCTTT 
CTGCAGAGCG TGTGCCACAC CGTAGTGGTA CAAGGGGTGT CGGCGCTGCT GGCCTTCCCC 
CAGAGCCAGG GCGAAATGAT GGAGCTGGAC TTGGTCAGCT CTGTCCTGCA CATCCCAGTG 
CTCAGCATAG TGCGCCACGA GTTTCCGCGG GAGAGTCAGA ATCCCCTGCA CCTACAGCTG 
AGTTTAGAAA ACTCACTAAG TTCTGATGCT GATGTCACTG TCTCAATCCT GACCATGAAC 
AACTGGTACA ATTTTAGCTT GTTGCTCTGC CAGGAAGACT GGAATATCAC GGACTTCCTC 
CTCCTTACGG AGAATAACTC CAAGTTCCAC CTCGAGTCTG TTATCAACAT CACTGCTAAT 
CTGTCCTCCA CAAAGGACCT TCTAAGTTTC CTGCAGGTCC AGATGGACAA CATTAGGAAC 
AGCACACCCA CAATGGTGAT GTTTGGCTGT GACATGGACA GTATCCGGCA GATATTTGAA 
ATGTCCACAC AGTTTGGGCT ATCACCTCCT GAACTTCACT GGGTTTTAGG AGACTCCCAG 
AATGTGGAGG AACTGAGGAC AGAAGGCCTG CCCTTAGGGC TCATTGCTCA TGGAAAAACC 
ACACAATCTG TCTTTGAGTA CTACGTTCAG GATGCCATGG AGTTGGTTGC AAGAGCTGTA 
GCCACAGCCA CCATGATCCA GCCAGAGCTT GCTCTCCTTC CCAGCACAAT GAACTGCATG 
GATGTGAAAA CCACAAATCT CACTTCTGGA CAGTATTTAT CAAGGTTTTT AGCCAACACC 
ACTTTCAGAG GTCTCAGTGG TTCCATCAAA GTAAAGGGCT CCACCATCAT CAGCTCAGAG 
AACAACTTTT TCATCTGGAA CTTGCAGCAC GACCCTATGG GAAAGCCAAT GTGGACTCGC 
CTGGGCAGCT GGCAAGGAGG AAGGATAGTC ATGGACTCTG GAATATGGCC AGAGCAGGCC 
CAGAGGCACA AAACCCACTT CCAGCACCCA AACAAGTTAC ACTTGAGAGT GGTGACATTG 
ATTGAACACC CATTTGTTTT CACGAGAGAA GTAGACGATG AAGGCTTATG CCCTGCTGGA 
CAGCTCTGTC TAGACCCTAT GACTAACGAC TCTTCCATGC TGGATCGTCT GTTTAGCAGC 
CTGCATAGCA GTAATGACAC AGTGCCAATC AAGTTCAAGA AGTGCTGTTA TGGGTACTGC 
ATCGATCTCC TGGAGCAGCT AGCAGAAGAC ATGAACTTTG ACTTTGACCT CTACATTGTA 
GGGGATGGAA AGTACGGAGC TTGGAAAAAT GGTCACTGGA CTGGGCTGGT TGGTGATCTC 
CTGAGTGGGA CAGCCAACAT GGCGGTCACT TCTTTCAGCA TCAATACCGC ACGAAGCCAG 
GTGATAGATT TCACCAGCCC TTTCTTCTCA ACCAGTTTGG GGATCTTAGT GAGGACTCGA 
GACACAGCAG CTCCAATTGG AGCCTTCATG TGGCCACTCC ACTGGACCAT GTGGCTGGGA 
ATTTTCGTGG CTCTCCATAT CACTGCCATT TTTCTCACTC TGTATGAATG GAAGAGCCCC 
TTTGGTATGA CCCCTAAGGG GAGGAACAGA AACAAAGTCT TCTCCTTCTC CTCAGCTTTG 
AATGTCTGCT ATGCCCTTCT GTTTGGCAGA ACAGCAGCCA TCAAACCCCC AAAATGCTGG 
ACTGGAAGGT TTCTGATGAA TCTTTGGGCC ATTTTCTGTA TGTTTTGCCT TTCTACATAC 
ACAGCGAACT TGGCTGCTGT CATGGTAGGT GAGAAGATCT ATGAAGAGCT TTCTGGAATT 
CATGACCCTA AGCTTCATCA TCCTTCTCAA GGCTTCCGCT TTGGAACTGT CCGGGAAAGC 
AGTGCTGAAG ACTATGTGCG CCAGAGCTTC CCAGAGATGC ATGAGTACAT GAGAAGGTAC 
AACGTGCCAG CCACCCCTGA TGGAGTGCAG TATCTGAAGA ATGATCCAGA GAAACTAGAC 
GCCTTCATCA TGGACAAAGC CCTTCTGGAT TATGAAGTGT CAATAGATGC TGACTGCAAG 
CTTCTGACCG TAGGAAAGCC ATTTGCCATC GAAGGATATG GCATTGGTCT CCCTCCAAAC 
TCTCCATTGA CCTCTAATAT ATCTGAGCTC ATCAGTCAGT ACAAGTCTCA CGGGTTTATG 
GATGTGCTCC ATGACAAGTG GTACAAGGTG GTTCCCTGCG GAAAGAGAAG CTTTGCCGTC 
ACTGAGACTT TGCAAATGGG CATCAAGCAC TTCTCTGGAC TCTTCGTGCT GTTGTGCATA 
GGATTTGGTC TCTCCATCCT GACCACCATT GGTGAACACA TAGTGCACAG ACTGCTGTTA 
CCACGCATCA AAAACAAATC CAAGCTGCAG TACTGGCTGC ACACGAGTCA GAGGTTTCAC 
AGAGCATTAA ACACGTCATT CGTAGAAGAA AAGCAGCCAC GTTCCAAGAC AAAACGTGTG 
GAGAAGAGGT CCAACCTGGG ACCCCAGCAG CTCATGGTAT GGAATACTTC CAATCTGAGT 
CATGACAACC AACGAAAATA CATCTTTAAT GACGAGGAAG GACAAAACCA GCTGGGTACC 
CAGGCCCACC AGGACATCCC TCTCCCTCAG AGGAGAAGAG AGCTCCCTGC CTCACTGACC 
ACCAATGGGA AAGCAGACTC CCTCAATGTA ACTCGGAGCT CCGTGATTCA GGAACTCTCT 
GAGTTGGAGA AGCAGATCCA AGTGATCCGC CAGGAGCTGC AGTTGGCTGT AAGCAGGAAG 
ACAGAGCTGG AGGAGTATCA AAAGACAAAT CGGACTTGTG AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grin3a ( NM_138546.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_612555.1 Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3A (Grin3a), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa44363
Clone ID Related Accession (Same CDS sequence)	NM_138546.2
Accession Version	NM_138546.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3408bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Rattus norvegicus(Norway rat)
Product	glutamate receptor ionotropic, NMDA 3A isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF073379.1 and BI294379.1. On Oct 9, 2014 this sequence version replaced NM_138546.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF073379.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGGAGAC TGAGTTTGTG GTGGCTGCTG AGCAGGGTCT GTCTGCTGCT GCCGCCGCCC 
TGCGCACTGG TGCTGGCCGG GGTGCCCAGC TCCTCCTCGC ACCCGCAACC CTGCCAGATC 
CTCAAGCGCA TCGGACACGC GGTGAGGGTG GGCGCGGTGC ACTTGCAACC CTGGACCACG 
GCCCCACGCG CAGCCAGTCG CGCTCAGGAA GGCGGCAGGG CGGGTGCCCA GAGGGATGAT 
CCAGAGTCCG GGACGTGGCG GCCACCGGCG CCCTCGCAAG GCGCACGCTG GTTGGGGAGC 
GCCCTGCATG GCCGGGGTCC ACCCGGCTCC CGAAAGCTCG GGGAGGGCGC GGGGGCCGAG 
ACCCTGTGGC CGCGGGATGC CCTACTGTTC GCTGTGGAAA ACTTGAACCG TGTGGAAGGG 
CTCCTACCCT ACAACCTGTC TTTGGAAGTA GTGATGGCCA TTGAGGCGGG CCTGGGCGAT 
CTGCCGCTTA TGCCCTTCTC TTCCCCAAGC TCACCGTGGA GCAGTGACCC TTTCTCCTTT 
CTGCAGAGCG TGTGCCACAC CGTAGTGGTA CAAGGGGTGT CGGCGCTGCT GGCCTTCCCC 
CAGAGCCAGG GCGAAATGAT GGAGCTGGAC TTGGTCAGCT CTGTCCTGCA CATCCCAGTG 
CTCAGCATAG TGCGCCACGA GTTTCCGCGG GAGAGTCAGA ATCCCCTGCA CCTACAGCTG 
AGTTTAGAAA ACTCACTAAG TTCTGATGCT GATGTCACTG TCTCAATCCT GACCATGAAC 
AACTGGTACA ATTTTAGCTT GTTGCTCTGC CAGGAAGACT GGAATATCAC GGACTTCCTC 
CTCCTTACGG AGAATAACTC CAAGTTCCAC CTCGAGTCTG TTATCAACAT CACTGCTAAT 
CTGTCCTCCA CAAAGGACCT TCTAAGTTTC CTGCAGGTCC AGATGGACAA CATTAGGAAC 
AGCACACCCA CAATGGTGAT GTTTGGCTGT GACATGGACA GTATCCGGCA GATATTTGAA 
ATGTCCACAC AGTTTGGGCT ATCACCTCCT GAACTTCACT GGGTTTTAGG AGACTCCCAG 
AATGTGGAGG AACTGAGGAC AGAAGGCCTG CCCTTAGGGC TCATTGCTCA TGGAAAAACC 
ACACAATCTG TCTTTGAGTA CTACGTTCAG GATGCCATGG AGTTGGTTGC AAGAGCTGTA 
GCCACAGCCA CCATGATCCA GCCAGAGCTT GCTCTCCTTC CCAGCACAAT GAACTGCATG 
GATGTGAAAA CCACAAATCT CACTTCTGGA CAGTATTTAT CAAGGTTTTT AGCCAACACC 
ACTTTCAGAG GTCTCAGTGG TTCCATCAAA GTAAAGGGCT CCACCATCAT CAGCTCAGAG 
AACAACTTTT TCATCTGGAA CTTGCAGCAC GACCCTATGG GAAAGCCAAT GTGGACTCGC 
CTGGGCAGCT GGCAAGGAGG AAGGATAGTC ATGGACTCTG GAATATGGCC AGAGCAGGCC 
CAGAGGCACA AAACCCACTT CCAGCACCCA AACAAGTTAC ACTTGAGAGT GGTGACATTG 
ATTGAACACC CATTTGTTTT CACGAGAGAA GTAGACGATG AAGGCTTATG CCCTGCTGGA 
CAGCTCTGTC TAGACCCTAT GACTAACGAC TCTTCCATGC TGGATCGTCT GTTTAGCAGC 
CTGCATAGCA GTAATGACAC AGTGCCAATC AAGTTCAAGA AGTGCTGTTA TGGGTACTGC 
ATCGATCTCC TGGAGCAGCT AGCAGAAGAC ATGAACTTTG ACTTTGACCT CTACATTGTA 
GGGGATGGAA AGTACGGAGC TTGGAAAAAT GGTCACTGGA CTGGGCTGGT TGGTGATCTC 
CTGAGTGGGA CAGCCAACAT GGCGGTCACT TCTTTCAGCA TCAATACCGC ACGAAGCCAG 
GTGATAGATT TCACCAGCCC TTTCTTCTCA ACCAGTTTGG GGATCTTAGT GAGGACTCGA 
GACACAGCAG CTCCAATTGG AGCCTTCATG TGGCCACTCC ACTGGACCAT GTGGCTGGGA 
ATTTTCGTGG CTCTCCATAT CACTGCCATT TTTCTCACTC TGTATGAATG GAAGAGCCCC 
TTTGGTATGA CCCCTAAGGG GAGGAACAGA AACAAAGTCT TCTCCTTCTC CTCAGCTTTG 
AATGTCTGCT ATGCCCTTCT GTTTGGCAGA ACAGCAGCCA TCAAACCCCC AAAATGCTGG 
ACTGGAAGGT TTCTGATGAA TCTTTGGGCC ATTTTCTGTA TGTTTTGCCT TTCTACATAC 
ACAGCGAACT TGGCTGCTGT CATGGTAGGT GAGAAGATCT ATGAAGAGCT TTCTGGAATT 
CATGACCCTA AGCTTCATCA TCCTTCTCAA GGCTTCCGCT TTGGAACTGT CCGGGAAAGC 
AGTGCTGAAG ACTATGTGCG CCAGAGCTTC CCAGAGATGC ATGAGTACAT GAGAAGGTAC 
AACGTGCCAG CCACCCCTGA TGGAGTGCAG TATCTGAAGA ATGATCCAGA GAAACTAGAC 
GCCTTCATCA TGGACAAAGC CCTTCTGGAT TATGAAGTGT CAATAGATGC TGACTGCAAG 
CTTCTGACCG TAGGAAAGCC ATTTGCCATC GAAGGATATG GCATTGGTCT CCCTCCAAAC 
TCTCCATTGA CCTCTAATAT ATCTGAGCTC ATCAGTCAGT ACAAGTCTCA CGGGTTTATG 
GATGTGCTCC ATGACAAGTG GTACAAGGTG GTTCCCTGCG GAAAGAGAAG CTTTGCCGTC 
ACTGAGACTT TGCAAATGGG CATCAAGCAC TTCTCTGGAC TCTTCGTGCT GTTGTGCATA 
GGATTTGGTC TCTCCATCCT GACCACCATT GGTGAACACA TAGTGCACAG ACTGCTGTTA 
CCACGCATCA AAAACAAATC CAAGCTGCAG TACTGGCTGC ACACGAGTCA GAGGTTTCAC 
AGAGCATTAA ACACGTCATT CGTAGAAGAA AAGCAGCCAC GTTCCAAGAC AAAACGTGTG 
GAGAAGAGCA GATGGAGAAG ATGGACCTGC AAGACAGAAG GGGACTCTGA ATTGTCTCTG 
TTTCCTAGGT CCAACCTGGG ACCCCAGCAG CTCATGGTAT GGAATACTTC CAATCTGAGT 
CATGACAACC AACGAAAATA CATCTTTAAT GACGAGGAAG GACAAAACCA GCTGGGTACC 
CAGGCCCACC AGGACATCCC TCTCCCTCAG AGGAGAAGAG AGCTCCCTGC CTCACTGACC 
ACCAATGGGA AAGCAGACTC CCTCAATGTA ACTCGGAGCT CCGTGATTCA GGAACTCTCT 
GAGTTGGAGA AGCAGATCCA AGTGATCCGC CAGGAGCTGC AGTTGGCTGT AAGCAGGAAG 
ACAGAGCTGG AGGAGTATCA AAAGACAAAT CGGACTTGTG AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612555.1
CDS	474..3881
Translation	MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITANLSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLTTNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES

Target ORF information:

RefSeq Version	NM_138546.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamate ionotropic receptor NMDA type subunit 3A (Grin3a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138546.2

ORF Insert Sequence:

ATGAGGAGAC TGAGTTTGTG GTGGCTGCTG AGCAGGGTCT GTCTGCTGCT GCCGCCGCCC 
TGCGCACTGG TGCTGGCCGG GGTGCCCAGC TCCTCCTCGC ACCCGCAACC CTGCCAGATC 
CTCAAGCGCA TCGGACACGC GGTGAGGGTG GGCGCGGTGC ACTTGCAACC CTGGACCACG 
GCCCCACGCG CAGCCAGTCG CGCTCAGGAA GGCGGCAGGG CGGGTGCCCA GAGGGATGAT 
CCAGAGTCCG GGACGTGGCG GCCACCGGCG CCCTCGCAAG GCGCACGCTG GTTGGGGAGC 
GCCCTGCATG GCCGGGGTCC ACCCGGCTCC CGAAAGCTCG GGGAGGGCGC GGGGGCCGAG 
ACCCTGTGGC CGCGGGATGC CCTACTGTTC GCTGTGGAAA ACTTGAACCG TGTGGAAGGG 
CTCCTACCCT ACAACCTGTC TTTGGAAGTA GTGATGGCCA TTGAGGCGGG CCTGGGCGAT 
CTGCCGCTTA TGCCCTTCTC TTCCCCAAGC TCACCGTGGA GCAGTGACCC TTTCTCCTTT 
CTGCAGAGCG TGTGCCACAC CGTAGTGGTA CAAGGGGTGT CGGCGCTGCT GGCCTTCCCC 
CAGAGCCAGG GCGAAATGAT GGAGCTGGAC TTGGTCAGCT CTGTCCTGCA CATCCCAGTG 
CTCAGCATAG TGCGCCACGA GTTTCCGCGG GAGAGTCAGA ATCCCCTGCA CCTACAGCTG 
AGTTTAGAAA ACTCACTAAG TTCTGATGCT GATGTCACTG TCTCAATCCT GACCATGAAC 
AACTGGTACA ATTTTAGCTT GTTGCTCTGC CAGGAAGACT GGAATATCAC GGACTTCCTC 
CTCCTTACGG AGAATAACTC CAAGTTCCAC CTCGAGTCTG TTATCAACAT CACTGCTAAT 
CTGTCCTCCA CAAAGGACCT TCTAAGTTTC CTGCAGGTCC AGATGGACAA CATTAGGAAC 
AGCACACCCA CAATGGTGAT GTTTGGCTGT GACATGGACA GTATCCGGCA GATATTTGAA 
ATGTCCACAC AGTTTGGGCT ATCACCTCCT GAACTTCACT GGGTTTTAGG AGACTCCCAG 
AATGTGGAGG AACTGAGGAC AGAAGGCCTG CCCTTAGGGC TCATTGCTCA TGGAAAAACC 
ACACAATCTG TCTTTGAGTA CTACGTTCAG GATGCCATGG AGTTGGTTGC AAGAGCTGTA 
GCCACAGCCA CCATGATCCA GCCAGAGCTT GCTCTCCTTC CCAGCACAAT GAACTGCATG 
GATGTGAAAA CCACAAATCT CACTTCTGGA CAGTATTTAT CAAGGTTTTT AGCCAACACC 
ACTTTCAGAG GTCTCAGTGG TTCCATCAAA GTAAAGGGCT CCACCATCAT CAGCTCAGAG 
AACAACTTTT TCATCTGGAA CTTGCAGCAC GACCCTATGG GAAAGCCAAT GTGGACTCGC 
CTGGGCAGCT GGCAAGGAGG AAGGATAGTC ATGGACTCTG GAATATGGCC AGAGCAGGCC 
CAGAGGCACA AAACCCACTT CCAGCACCCA AACAAGTTAC ACTTGAGAGT GGTGACATTG 
ATTGAACACC CATTTGTTTT CACGAGAGAA GTAGACGATG AAGGCTTATG CCCTGCTGGA 
CAGCTCTGTC TAGACCCTAT GACTAACGAC TCTTCCATGC TGGATCGTCT GTTTAGCAGC 
CTGCATAGCA GTAATGACAC AGTGCCAATC AAGTTCAAGA AGTGCTGTTA TGGGTACTGC 
ATCGATCTCC TGGAGCAGCT AGCAGAAGAC ATGAACTTTG ACTTTGACCT CTACATTGTA 
GGGGATGGAA AGTACGGAGC TTGGAAAAAT GGTCACTGGA CTGGGCTGGT TGGTGATCTC 
CTGAGTGGGA CAGCCAACAT GGCGGTCACT TCTTTCAGCA TCAATACCGC ACGAAGCCAG 
GTGATAGATT TCACCAGCCC TTTCTTCTCA ACCAGTTTGG GGATCTTAGT GAGGACTCGA 
GACACAGCAG CTCCAATTGG AGCCTTCATG TGGCCACTCC ACTGGACCAT GTGGCTGGGA 
ATTTTCGTGG CTCTCCATAT CACTGCCATT TTTCTCACTC TGTATGAATG GAAGAGCCCC 
TTTGGTATGA CCCCTAAGGG GAGGAACAGA AACAAAGTCT TCTCCTTCTC CTCAGCTTTG 
AATGTCTGCT ATGCCCTTCT GTTTGGCAGA ACAGCAGCCA TCAAACCCCC AAAATGCTGG 
ACTGGAAGGT TTCTGATGAA TCTTTGGGCC ATTTTCTGTA TGTTTTGCCT TTCTACATAC 
ACAGCGAACT TGGCTGCTGT CATGGTAGGT GAGAAGATCT ATGAAGAGCT TTCTGGAATT 
CATGACCCTA AGCTTCATCA TCCTTCTCAA GGCTTCCGCT TTGGAACTGT CCGGGAAAGC 
AGTGCTGAAG ACTATGTGCG CCAGAGCTTC CCAGAGATGC ATGAGTACAT GAGAAGGTAC 
AACGTGCCAG CCACCCCTGA TGGAGTGCAG TATCTGAAGA ATGATCCAGA GAAACTAGAC 
GCCTTCATCA TGGACAAAGC CCTTCTGGAT TATGAAGTGT CAATAGATGC TGACTGCAAG 
CTTCTGACCG TAGGAAAGCC ATTTGCCATC GAAGGATATG GCATTGGTCT CCCTCCAAAC 
TCTCCATTGA CCTCTAATAT ATCTGAGCTC ATCAGTCAGT ACAAGTCTCA CGGGTTTATG 
GATGTGCTCC ATGACAAGTG GTACAAGGTG GTTCCCTGCG GAAAGAGAAG CTTTGCCGTC 
ACTGAGACTT TGCAAATGGG CATCAAGCAC TTCTCTGGAC TCTTCGTGCT GTTGTGCATA 
GGATTTGGTC TCTCCATCCT GACCACCATT GGTGAACACA TAGTGCACAG ACTGCTGTTA 
CCACGCATCA AAAACAAATC CAAGCTGCAG TACTGGCTGC ACACGAGTCA GAGGTTTCAC 
AGAGCATTAA ACACGTCATT CGTAGAAGAA AAGCAGCCAC GTTCCAAGAC AAAACGTGTG 
GAGAAGAGCA GATGGAGAAG ATGGACCTGC AAGACAGAAG GGGACTCTGA ATTGTCTCTG 
TTTCCTAGGT CCAACCTGGG ACCCCAGCAG CTCATGGTAT GGAATACTTC CAATCTGAGT 
CATGACAACC AACGAAAATA CATCTTTAAT GACGAGGAAG GACAAAACCA GCTGGGTACC 
CAGGCCCACC AGGACATCCC TCTCCCTCAG AGGAGAAGAG AGCTCCCTGC CTCACTGACC 
ACCAATGGGA AAGCAGACTC CCTCAATGTA ACTCGGAGCT CCGTGATTCA GGAACTCTCT 
GAGTTGGAGA AGCAGATCCA AGTGATCCGC CAGGAGCTGC AGTTGGCTGT AAGCAGGAAG 
ACAGAGCTGG AGGAGTATCA AAAGACAAAT CGGACTTGTG AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Glycine induces bidirectional modifications in N-methyl-D-aspartate receptor-mediated synaptic responses in hippocampal CA1 neurons.
The Journal of biological chemistry289(45)31200-11(2014 Nov)
Zhang XY,Ji F,Wang N,Chen LL,Tian T,Lu W

Synapse-specific control of experience-dependent plasticity by presynaptic NMDA receptors.
Neuron83(4)879-93(2014 Aug)
Larsen RS,Smith IT,Miriyala J,Han JE,Corlew RJ,Smith SL,Philpot BD

Gestational chronodisruption impairs hippocampal expression of NMDA receptor subunits Grin1b/Grin3a and spatial memory in the adult offspring.
PloS one9(3)e91313(2014)
Vilches N,Spichiger C,Mendez N,Abarzua-Catalan L,Galdames HA,Hazlerigg DG,Richter HG,Torres-Farfan C

GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling.
Proceedings of the National Academy of Sciences of the United States of America110(51)20807-12(2013 Dec)
Fiuza M,González-González I,Pérez-Otaño I

Expression of cocaine-evoked synaptic plasticity by GluN3A-containing NMDA receptors.
Neuron80(4)1025-38(2013 Nov)
Yuan T,Mameli M,O'Connor EC,O' Connor EC,Dey PN,Verpelli C,Sala C,Perez-Otano I,Lüscher C,Bellone C

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Grin3a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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