Trpm4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Trpm4
Entrez Gene ID	171143
Full Name	transient receptor potential cation channel, subfamily M, member 4
Synonyms	LTrpC-4,Mls2s
General protein information	Preferred Names transient receptor potential cation channel, subfamily M, member 4 Names transient receptor potential cation channel subfamily M member 4 LTrpC4 calcium-activated non-selective cation channel 1 long transient receptor potential channel 4 melastatin like 2 protein melastatin-like 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22
Summary	member of a family of calcium permeable channels [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001136229.1	NP_001129701.1	transient receptor potential cation channel subfamily M member 4

Pathways from BioSystems

Homologies

Homo sapiens (human)	TRPM4	NP_060106.2
Canis lupus familiaris (dog)	TRPM4	XP_541500.3
Mus musculus (house mouse)	Trpm4	NP_780339.2
Danio rerio (zebrafish)	LOC100334234	XP_003199613.2
Danio rerio (zebrafish)	LOC100333667	XP_002663943.3
Pan troglodytes (chimpanzee)	TRPM4	XP_512811.2
Rattus norvegicus (Norway rat)	Trpm4	NP_001129701.1
Danio rerio (zebrafish)	trpm4c	XP_001339981.5
Bos taurus (cattle)	TRPM4	XP_002695251.2
Macaca mulatta (Rhesus monkey)	LOC719120	XP_001112814.2
Danio rerio (zebrafish)	trpm4a	XP_003198181.2
Xenopus tropicalis (tropical clawed frog)	trpm5	XP_004916436.1

Gene Ontology
Bibliography

Related articles in PubMed

TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca
Yamaguchi S, Tanimoto A, Iwasa S, Otsuguro KI
International journal of molecular sciences20(8)(2019 Apr)

Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury.
Chen B, Ng G, Gao Y, Low SW, Sandanaraj E, Ramasamy B, Sekar S, Bhakoo K, Soong TW, Nilius B, Tang C, Robins EG, Goggi J, Liao P
Translational stroke research10(1)91-103(2019 02)

Disentangling the role of TRPM4 in hippocampus-dependent plasticity and learning: an electrophysiological, behavioral and FMRI approach.
Bovet-Carmona M, Menigoz A, Pinto S, Tambuyzer T, Krautwald K, Voets T, Aerts JM, Angenstein F, Vennekens R, Balschun D
Brain structure & function223(8)3557-3576(2018 Nov)

Transient Receptor Potential Melastatin 4 Induces Astrocyte Swelling But Not Death after Diffuse Traumatic Brain Injury.
Gorse KM, Lantzy MK, Lee ED, Lafrenaye AD
Journal of neurotrauma35(14)1694-1704(2018 07)

Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits.
Koizumi H, John TT, Chia JX, Tariq MF, Phillips RS, Mosher B, Chen Y, Thompson R, Zhang R, Koshiya N, Smith JC
eNeuro5(1)(2018 Jan-Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Trpm4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trpm4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13323	NM_001136229.1 Latest version!	Rattus norvegicus transient receptor potential cation channel, subfamily M, member 4 (Trpm4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Trpm4 ( NM_001136229.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001129701.1 Rattus norvegicus transient receptor potential cation channel, subfamily M, member 4 (Trpm4), mRNA.

Price & Availability↑

CloneID	ORa13323
Clone ID Related Accession (Same CDS sequence)	NM_001136229.1
Accession Version	NM_001136229.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573315200000
Organism	Rattus norvegicus(Norway rat)
Product	transient receptor potential cation channel subfamily M member 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC095435.10. On Oct 28, 2008 this sequence version replaced XM_574447.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGGTGGGGC AGGAGAAAGA GCAGAGTTGG ATCCCTAAGA TCTTCAGGAA GAAGGTGTGC 
ACGACGTTCA TAGTGGACCT CCACGATGAT GCGGGAGGGA CCTTGTGCCA GTGTGGGCAA 
CCTCGGGATG CCCACCCTTC TGTGGCTGTG GAGGATGCCT TTGGGGCAGC CGTAGTTACC 
GAGTGGAACA GTGATGAGCA CACCACGGAG AAGCCCACAG ATGCCTACGG GGACCTGGAC 
TTCACATACT CTGGCCGAAA GTCCAGCAAC TTCCTCCGGC TGTCTGATCG CACGGATCCG 
GCCACTGTGT ACAGTCTCGT CACCCGCTCT TGGGGCTTTC GTGCTCCAAA CTTGGTGGTG 
TCAGTGCTGG GGGGGTCGGA GGGCCCCGTG CTACAGACCT GGCTGCAGGA CCTTCTGCGT 
CGTGGGCTGG TGCGAGCAGC CCAGAGCACA GGGGCCTGGA TCGTCACTGG GGGACTGCAC 
ACAGGCATTG GTCGGCATGT GGGTGTGGCT GTGAGGGACC ACCAGACGGC CAGCACCGGG 
GGCAGCAAGG TGGTGGCCAT GGGTGTGGCC CCCTGGGGAG TGGTCCGGAA CAGAGACATG 
CTGATCAACC CCAAGGGCTC ATTCCCTGCA AGATACCGGT GGCGTGGTGA CCCTGAGGAC 
GGAGTTGAGT TCCCCCTGGA CTATAACTAT TCTGCTTTCT TCTTGGTGGA TGATGGTACC 
TATGGCCGCA TGGGTGGTGA GAACCGCTTC CGCCTTCGGT TTGAGTCCTA TGTGGCTCAG 
CAGAAGACCG GAGTGGGAGG GACTGGAATT GACATCCCTG TACTCCTTCT TCTCATCGAA 
GGCGATGAGA AGATGTTAAA GCGGATAGAG GATGCCACCC AGGCTCAGCT CCCCTGCCTC 
TTGGTGGCTG GCTCTGGGGG TGCTGCAGAC TGCCTGGTGG AGACCCTGGA AGATACTCTG 
GCCCCAGGGA GTGGGGGACT CAGGCGAGGT GAAGCCCGGG ATCGAATTAG ACGTTACTTC 
CCTAAAGGAG ACCCCGAGGT CCTGCAGGCC CAGGTAGAGA GGATCATGAC CCGAAAGGAG 
CTGCTGACAG TCTATTCATC AGAGGACGGC TCCGAGGAGT TTGAGACTAT CGTTTTGAGG 
GCTCTTGTGA AAGCCTGTGG GAGCTCCGAG GCCTCGGCTT ACCTGGATGA ACTGCGTTTG 
GCTGTGGCTT GGAACCGCGT GGACATCGCC CAAAGTGAAC TTTTCCGTGG GGACATCCAG 
TGGCGGTCCT TCCACCTGGA GGCCTCTCTC ATGGACGCTC TGCTGAATGA CCGGCCTGAG 
TTTGTGCGCT TGCTCATCTC CCATGGCCTT AGTCTGGGAC ACTTCCTGAC CCCCGTGCGC 
CTGGCCCAGC TGTACAGCGC AGTGTCCCCC AACTCGCTGA TCCGCAATCT TCTGGACCAG 
GCGTCCCACG CTAGTAGCAG CAAATCTCCA CCTGCAAATG GAGCTGCAGA GCTCCGGCCT 
CCTAATGTGG GGCAAGTTCT GAGGACTCTG TTGGGAGAAA CGTGTGCACC GCGGTACCCC 
GCCAGGAACA CCCGACACTC CCTGCTGGGC CAGGACCACA GAGAGAATGA CTCTCTGCTC 
ATGGACTGGG CCAACATGCA ACAGGATGCA AGCTTTGAAC AAGCCCCCTG GAGTGACCTG 
CTTATCTGGG CTCTGTTGTT GAACCGAGCC CAGATGGCCA TTTATTTCTG GGAGAAGGGC 
TCCAACTCAG TGGCCTCTGC TCTCGGGGCT TGTCTCTTAC TCCGAGTGAT GGCTCGCCTT 
GAGTGGGAGG CTGAGGAAGC TGCACGGCGG AAGGACCTTG CTGCCAAGTT TGAAAGCATG 
AGCGTGGACC TCTTTGGAGA GTGTTACCAC AACAGTGAAT ATCGAGCAGC CCGCCTTCTT 
CTGCGTCGCT GTCCCCTCTG GGGAGAGGCC ACCTGTCTCC AGCTTGCCAT GCAGGCTGAC 
GCCCGTGCGT TCTTTGCCCA GGATGGAGTA CAGTCTCTGC TGACACAGAA GTGGTGGGGG 
GAGATGGACA GCACGAACCC TATCTGGGCC CTGCTTCTCA CCTTCTTCTG CCCGCCTCTC 
ATCTACACCA ACCTCATCCT CTTCAGGAAG TCAGAGGAGG AGCCCACACA GAAGGATCTT 
GACTTCGATA TGGACAGCAG CATGAATGGA GCAGGTCCTC TTGGGCCTGC GGAGCCCTCA 
GCAAAGGTGG CCCTTGAGAG GCGGCGGCGG CGGCGGCCAG GACATACCCT CTGCTGTGGC 
GGGTGCTCCA AGCGCTGGTC GTACTTTTGG GGCGCCCCAG TGACCGCCTT CCTGGGTAAC 
GTGGTCAGTT ACCTGCTGTT CCTGCTGCTG TTTGCACACG TGTTGCTGGT GGATTTCCAG 
CCTACAAAGC CGGGCGTCTT CGAGCTGCTG CTGTACTTCT GGGCCTTCAC GCTGCTATGC 
GAGGAGCTGC GCCAGGGCCT GGGCGGTGGC TGGGGTACCC TGGCCAACGG GGGACCTGGT 
CCTGGCAAAG CTCCCCTGCG CCATCGTCTG CACCTCTACC TCTTGGATAC TTGGAACCAG 
TGCGACTTGC TGGCACTCAC CTGCTTCCTG CTGGGCGTTG GCTGCAGGCT GACTCCTGGC 
CTGTTTGACT TGGGACGCAC AGTCCTCTGT CTTGACTTCA TGATCTTCAC ACTGCGCCTG 
CTGCACATCT TCACGGTGAA CAAGCAGCTG GGGCCCAAGA TTGTCATCGT GAGCAAGATG 
ATGAAGGATG TATTCTTTTT CCTCTTCTTC CTCTGCGTGT GGCTTGTAGC TTATGGGGTG 
GCCACAGAGG GGATCCTGAG GCCCCAGGAC CGCAGTCTAC CGAGCATCCT GCGCAGGGTC 
TTCTACCGTC CGTATCTGCA GATCTTCGGA CAAATTCCCC AGGAGGAAAT GGATGTGGCC 
CTCATGAATC CCAGTAACTG CTCTGCCGAG CGGGGCTCCT GGGCTCACCC GGAGGGGCCG 
GTCGCAGGCT CCTGTGTGTC CCAGTATGCC AACTGGCTGG TGGTGTTGCT CCTCATCGTC 
TTCTTGCTGG TGGCCAATAT CCTGCTGCTC AATCTGCTCA TCGCCATGTT CAGCTACACC 
TTCAACAAAG TGCATGGCAA CAGCGACCTC TACTGGAAGG CGCAGCGCTA CAGCCTCATC 
CGGGAATTCC ATTCGCGGCC TGCCCTGGCC CCACCCCTCA TCATCATCTC TCACCTGCGT 
CTCCTCTTCA AGTGGCTGCG CAGGTGTCAT AGGACTAACT TGCCCGCCTC CCCAGTCTTC 
GAGCACTTCC GTGTCTGTCT CTCTAAGGAA GCAGAGAGGA CGCTGCTGAC TTGGGAGTCT 
GTGCACAAAG AGAACTTCCT ATTGGCACAA GCTCGTGACA AGCGAGACAG CGACTCGGAG 
CGTCTGAAAC GCACGTCCCA GAAGGTGGAC ACTGCACTGA AGCAGCTGGG ACAGATCAGA 
GAGTATGACC GGCGTCTGAG GGGGCTGGAG AGAGAGGTCC AACACTGTTC TCGAGTCCTG 
ACTTGGATGG CTGAGGCCCT TAGCCACTCT GCCTTACTGC CTCCAGGGGG GCCACCCCCT 
CCAAGCCCCA CTGGGTCCAA AGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129701.1
CDS	47..3673
Translation	MVGQEKEQSWIPKIFRKKVCTTFIVDLHDDAGGTLCQCGQPRDAHPSVAVEDAFGAAVVTEWNSDEHTTEKPTDAYGDLDFTYSGRKSSNFLRLSDRTDPATVYSLVTRSWGFRAPNLVVSVLGGSEGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQTASTGGSKVVAMGVAPWGVVRNRDMLINPKGSFPARYRWRGDPEDGVEFPLDYNYSAFFLVDDGTYGRMGGENRFRLRFESYVAQQKTGVGGTGIDIPVLLLLIEGDEKMLKRIEDATQAQLPCLLVAGSGGAADCLVETLEDTLAPGSGGLRRGEARDRIRRYFPKGDPEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLRALVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPVRLAQLYSAVSPNSLIRNLLDQASHASSSKSPPANGAAELRPPNVGQVLRTLLGETCAPRYPARNTRHSLLGQDHRENDSLLMDWANMQQDASFEQAPWSDLLIWALLLNRAQMAIYFWEKGSNSVASALGACLLLRVMARLEWEAEEAARRKDLAAKFESMSVDLFGECYHNSEYRAARLLLRRCPLWGEATCLQLAMQADARAFFAQDGVQSLLTQKWWGEMDSTNPIWALLLTFFCPPLIYTNLILFRKSEEEPTQKDLDFDMDSSMNGAGPLGPAEPSAKVALERRRRRRPGHTLCCGGCSKRWSYFWGAPVTAFLGNVVSYLLFLLLFAHVLLVDFQPTKPGVFELLLYFWAFTLLCEELRQGLGGGWGTLANGGPGPGKAPLRHRLHLYLLDTWNQCDLLALTCFLLGVGCRLTPGLFDLGRTVLCLDFMIFTLRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLCVWLVAYGVATEGILRPQDRSLPSILRRVFYRPYLQIFGQIPQEEMDVALMNPSNCSAERGSWAHPEGPVAGSCVSQYANWLVVLLLIVFLLVANILLLNLLIAMFSYTFNKVHGNSDLYWKAQRYSLIREFHSRPALAPPLIIISHLRLLFKWLRRCHRTNLPASPVFEHFRVCLSKEAERTLLTWESVHKENFLLAQARDKRDSDSERLKRTSQKVDTALKQLGQIREYDRRLRGLEREVQHCSRVLTWMAEALSHSALLPPGGPPPPSPTGSKD

Target ORF information:

RefSeq Version	NM_001136229.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transient receptor potential cation channel, subfamily M, member 4 (Trpm4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136229.1

ORF Insert Sequence:

ATGGTGGGGC AGGAGAAAGA GCAGAGTTGG ATCCCTAAGA TCTTCAGGAA GAAGGTGTGC 
ACGACGTTCA TAGTGGACCT CCACGATGAT GCGGGAGGGA CCTTGTGCCA GTGTGGGCAA 
CCTCGGGATG CCCACCCTTC TGTGGCTGTG GAGGATGCCT TTGGGGCAGC CGTAGTTACC 
GAGTGGAACA GTGATGAGCA CACCACGGAG AAGCCCACAG ATGCCTACGG GGACCTGGAC 
TTCACATACT CTGGCCGAAA GTCCAGCAAC TTCCTCCGGC TGTCTGATCG CACGGATCCG 
GCCACTGTGT ACAGTCTCGT CACCCGCTCT TGGGGCTTTC GTGCTCCAAA CTTGGTGGTG 
TCAGTGCTGG GGGGGTCGGA GGGCCCCGTG CTACAGACCT GGCTGCAGGA CCTTCTGCGT 
CGTGGGCTGG TGCGAGCAGC CCAGAGCACA GGGGCCTGGA TCGTCACTGG GGGACTGCAC 
ACAGGCATTG GTCGGCATGT GGGTGTGGCT GTGAGGGACC ACCAGACGGC CAGCACCGGG 
GGCAGCAAGG TGGTGGCCAT GGGTGTGGCC CCCTGGGGAG TGGTCCGGAA CAGAGACATG 
CTGATCAACC CCAAGGGCTC ATTCCCTGCA AGATACCGGT GGCGTGGTGA CCCTGAGGAC 
GGAGTTGAGT TCCCCCTGGA CTATAACTAT TCTGCTTTCT TCTTGGTGGA TGATGGTACC 
TATGGCCGCA TGGGTGGTGA GAACCGCTTC CGCCTTCGGT TTGAGTCCTA TGTGGCTCAG 
CAGAAGACCG GAGTGGGAGG GACTGGAATT GACATCCCTG TACTCCTTCT TCTCATCGAA 
GGCGATGAGA AGATGTTAAA GCGGATAGAG GATGCCACCC AGGCTCAGCT CCCCTGCCTC 
TTGGTGGCTG GCTCTGGGGG TGCTGCAGAC TGCCTGGTGG AGACCCTGGA AGATACTCTG 
GCCCCAGGGA GTGGGGGACT CAGGCGAGGT GAAGCCCGGG ATCGAATTAG ACGTTACTTC 
CCTAAAGGAG ACCCCGAGGT CCTGCAGGCC CAGGTAGAGA GGATCATGAC CCGAAAGGAG 
CTGCTGACAG TCTATTCATC AGAGGACGGC TCCGAGGAGT TTGAGACTAT CGTTTTGAGG 
GCTCTTGTGA AAGCCTGTGG GAGCTCCGAG GCCTCGGCTT ACCTGGATGA ACTGCGTTTG 
GCTGTGGCTT GGAACCGCGT GGACATCGCC CAAAGTGAAC TTTTCCGTGG GGACATCCAG 
TGGCGGTCCT TCCACCTGGA GGCCTCTCTC ATGGACGCTC TGCTGAATGA CCGGCCTGAG 
TTTGTGCGCT TGCTCATCTC CCATGGCCTT AGTCTGGGAC ACTTCCTGAC CCCCGTGCGC 
CTGGCCCAGC TGTACAGCGC AGTGTCCCCC AACTCGCTGA TCCGCAATCT TCTGGACCAG 
GCGTCCCACG CTAGTAGCAG CAAATCTCCA CCTGCAAATG GAGCTGCAGA GCTCCGGCCT 
CCTAATGTGG GGCAAGTTCT GAGGACTCTG TTGGGAGAAA CGTGTGCACC GCGGTACCCC 
GCCAGGAACA CCCGACACTC CCTGCTGGGC CAGGACCACA GAGAGAATGA CTCTCTGCTC 
ATGGACTGGG CCAACATGCA ACAGGATGCA AGCTTTGAAC AAGCCCCCTG GAGTGACCTG 
CTTATCTGGG CTCTGTTGTT GAACCGAGCC CAGATGGCCA TTTATTTCTG GGAGAAGGGC 
TCCAACTCAG TGGCCTCTGC TCTCGGGGCT TGTCTCTTAC TCCGAGTGAT GGCTCGCCTT 
GAGTGGGAGG CTGAGGAAGC TGCACGGCGG AAGGACCTTG CTGCCAAGTT TGAAAGCATG 
AGCGTGGACC TCTTTGGAGA GTGTTACCAC AACAGTGAAT ATCGAGCAGC CCGCCTTCTT 
CTGCGTCGCT GTCCCCTCTG GGGAGAGGCC ACCTGTCTCC AGCTTGCCAT GCAGGCTGAC 
GCCCGTGCGT TCTTTGCCCA GGATGGAGTA CAGTCTCTGC TGACACAGAA GTGGTGGGGG 
GAGATGGACA GCACGAACCC TATCTGGGCC CTGCTTCTCA CCTTCTTCTG CCCGCCTCTC 
ATCTACACCA ACCTCATCCT CTTCAGGAAG TCAGAGGAGG AGCCCACACA GAAGGATCTT 
GACTTCGATA TGGACAGCAG CATGAATGGA GCAGGTCCTC TTGGGCCTGC GGAGCCCTCA 
GCAAAGGTGG CCCTTGAGAG GCGGCGGCGG CGGCGGCCAG GACATACCCT CTGCTGTGGC 
GGGTGCTCCA AGCGCTGGTC GTACTTTTGG GGCGCCCCAG TGACCGCCTT CCTGGGTAAC 
GTGGTCAGTT ACCTGCTGTT CCTGCTGCTG TTTGCACACG TGTTGCTGGT GGATTTCCAG 
CCTACAAAGC CGGGCGTCTT CGAGCTGCTG CTGTACTTCT GGGCCTTCAC GCTGCTATGC 
GAGGAGCTGC GCCAGGGCCT GGGCGGTGGC TGGGGTACCC TGGCCAACGG GGGACCTGGT 
CCTGGCAAAG CTCCCCTGCG CCATCGTCTG CACCTCTACC TCTTGGATAC TTGGAACCAG 
TGCGACTTGC TGGCACTCAC CTGCTTCCTG CTGGGCGTTG GCTGCAGGCT GACTCCTGGC 
CTGTTTGACT TGGGACGCAC AGTCCTCTGT CTTGACTTCA TGATCTTCAC ACTGCGCCTG 
CTGCACATCT TCACGGTGAA CAAGCAGCTG GGGCCCAAGA TTGTCATCGT GAGCAAGATG 
ATGAAGGATG TATTCTTTTT CCTCTTCTTC CTCTGCGTGT GGCTTGTAGC TTATGGGGTG 
GCCACAGAGG GGATCCTGAG GCCCCAGGAC CGCAGTCTAC CGAGCATCCT GCGCAGGGTC 
TTCTACCGTC CGTATCTGCA GATCTTCGGA CAAATTCCCC AGGAGGAAAT GGATGTGGCC 
CTCATGAATC CCAGTAACTG CTCTGCCGAG CGGGGCTCCT GGGCTCACCC GGAGGGGCCG 
GTCGCAGGCT CCTGTGTGTC CCAGTATGCC AACTGGCTGG TGGTGTTGCT CCTCATCGTC 
TTCTTGCTGG TGGCCAATAT CCTGCTGCTC AATCTGCTCA TCGCCATGTT CAGCTACACC 
TTCAACAAAG TGCATGGCAA CAGCGACCTC TACTGGAAGG CGCAGCGCTA CAGCCTCATC 
CGGGAATTCC ATTCGCGGCC TGCCCTGGCC CCACCCCTCA TCATCATCTC TCACCTGCGT 
CTCCTCTTCA AGTGGCTGCG CAGGTGTCAT AGGACTAACT TGCCCGCCTC CCCAGTCTTC 
GAGCACTTCC GTGTCTGTCT CTCTAAGGAA GCAGAGAGGA CGCTGCTGAC TTGGGAGTCT 
GTGCACAAAG AGAACTTCCT ATTGGCACAA GCTCGTGACA AGCGAGACAG CGACTCGGAG 
CGTCTGAAAC GCACGTCCCA GAAGGTGGAC ACTGCACTGA AGCAGCTGGG ACAGATCAGA 
GAGTATGACC GGCGTCTGAG GGGGCTGGAG AGAGAGGTCC AACACTGTTC TCGAGTCCTG 
ACTTGGATGG CTGAGGCCCT TAGCCACTCT GCCTTACTGC CTCCAGGGGG GCCACCCCCT 
CCAAGCCCCA CTGGGTCCAA AGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca
International journal of molecular sciences20(8)(2019 Apr)
Yamaguchi S,Tanimoto A,Iwasa S,Otsuguro KI

Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury.
Translational stroke research10(1)91-103(2019 02)
Chen B,Ng G,Gao Y,Low SW,Sandanaraj E,Ramasamy B,Sekar S,Bhakoo K,Soong TW,Nilius B,Tang C,Robins EG,Goggi J,Liao P

Disentangling the role of TRPM4 in hippocampus-dependent plasticity and learning: an electrophysiological, behavioral and FMRI approach.
Brain structure & function223(8)3557-3576(2018 Nov)
Bovet-Carmona M,Menigoz A,Pinto S,Tambuyzer T,Krautwald K,Voets T,Aerts JM,Angenstein F,Vennekens R,Balschun D

Transient Receptor Potential Melastatin 4 Induces Astrocyte Swelling But Not Death after Diffuse Traumatic Brain Injury.
Journal of neurotrauma35(14)1694-1704(2018 07)
Gorse KM,Lantzy MK,Lee ED,Lafrenaye AD

Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits.
eNeuro5(1)(2018 Jan-Feb)
Koizumi H,John TT,Chia JX,Tariq MF,Phillips RS,Mosher B,Chen Y,Thompson R,Zhang R,Koshiya N,Smith JC

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Trpm4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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