Kank2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kank2
Entrez Gene ID	100361376
Full Name	KN motif and ankyrin repeat domains 2
Synonyms	RGD1563532
General protein information	Preferred Names KN motif and ankyrin repeat domains 2 Names KN motif and ankyrin repeat domain-containing protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q13

mRNA and Protein(s)

mRNA	Protein	Name
XM_006242590.3	XP_006242652.1	KN motif and ankyrin repeat domain-containing protein 2 isoform X1
XM_006242589.3	XP_006242651.1	KN motif and ankyrin repeat domain-containing protein 2 isoform X1
NM_001270413.1	NP_001257342.1	KN motif and ankyrin repeat domain-containing protein 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KANK2	XP_003432823.1
Rattus norvegicus (Norway rat)	Kank2	NP_001257342.1
Pan troglodytes (chimpanzee)	KANK2	XP_003316135.1
Bos taurus (cattle)	KANK2	NP_001069999.1
Mus musculus (house mouse)	Kank2	NP_663586.3
Homo sapiens (human)	KANK2	NP_001129663.1
Danio rerio (zebrafish)	LOC571549	XP_005164397.1
Xenopus tropicalis (tropical clawed frog)	kank2	XP_002942889.2

Gene Ontology
Bibliography

Related articles in PubMed

KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
Gee HY, Zhang F, Ashraf S, Kohl S, Sadowski CE, Vega-Warner V, Zhou W, Lovric S, Fang H, Nettleton M, Zhu JY, Hoefele J, Weber LT, Podracka L, Boor A, Fehrenbach H, Innis JW, Washburn J, Levy S, Lifton RP, Otto EA, Han Z, Hildebrandt F
The Journal of clinical investigation125(6)2375-84(2015 Jun)

Mutation in KANK2, encoding a sequestering protein for steroid receptor coactivators, causes keratoderma and woolly hair.
Ramot Y, Molho-Pessach V, Meir T, Alper-Pinus R, Siam I, Tams S, Babay S, Zlotogorski A
Journal of medical genetics51(6)388-94(2014 Jun)

Steroid receptor coactivator-interacting protein (SIP) inhibits caspase-independent apoptosis by preventing apoptosis-inducing factor (AIF) from being released from mitochondria.
Wang D, Liang J, Zhang Y, Gui B, Wang F, Yi X, Sun L, Yao Z, Shang Y
The Journal of biological chemistry287(16)12612-21(2012 Apr)

SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.
Zhang Y, Zhang H, Liang J, Yu W, Shang Y
The EMBO journal26(11)2645-57(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kank2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kank2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09251	NM_001270413.1 Latest version!	Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
ORa30874	XM_006242589.3 Latest version!	Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
ORa30874	XM_006242590.3 Latest version!	Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kank2 ( NM_001270413.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257342.1 Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), mRNA.

Price & Availability↑

CloneID	ORa09251
Clone ID Related Accession (Same CDS sequence)	NM_001270413.1
Accession Version	NM_001270413.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Rattus norvegicus(Norway rat)
Product	KN motif and ankyrin repeat domain-containing protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC119556.5. On Jul 4, 2012 this sequence version replaced XM_002729875.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689599, SAMN02642809 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCAGG TCCTGCATGT GCCCGCCCCA TTCCCAGGAA CCCCTGGCCA AGCCTCCTCA 
GCGGCCTTCC CCAACAAGGA GCCAGACCCG CCATACTCGG TGGAGACGCC CTATGGCTAC 
CGCCTGGACC TGGACTTTCT TAAGTACGTG GATGACATTG AGAAGGGCCA CACACTGCGC 
AGGGTGCCGG TGCAGCGCCG GCCACGCCTG GGCTCCCTGC CACGTGGCCC GGGCTCCTGG 
TGGACGTCCA CAGAGTCGCT GTGCTCTGAC GCCAGTGGGG ACAGCCGGCA CTCGGCCTAC 
TCCTACTGTG GCCGCGGCTT CTACCCACAG TACGGAGCCT TGGAGACCCG CAGCGGCACC 
AACCCACGCG TGGAACGCAC GCTGCTGGAT GCGCGGCGCC GACTGGAGGA CCAGGCGGCT 
GCCCCATCAT CGGGTGGCCT GGGCTCTCTG ACGCCCAGCG CTGCGGGCTC CACCAGCTCC 
CTGGCAGGCG TGGGCCTGCT GCCCCCCACA CCTCGCAGCT CTGGCTTGTC CACCCCAGTG 
GCACCCAGCG CTGGTCACCT GGCCCACGTG CGCGAACAGA TGGCTGGAGC CCTGCGCAAG 
CTGCGCCAGC TGGAGGAGCA GGTCAAGCTG ATCCCCGTGC TCCAGGTCAA GCTGTCGGTG 
CTCCAGGAGG AAAAAAGACA GCTCACCGTG CAGCTCAAGA GCCAGAAGTT TCTAGGCCAC 
CCCTCAGGGA CAAGGAGCCG GAGCGAGCTC TGCCTGGACC TTCCGGAGGC CCCCGACGAC 
CCTGCTGTGC TAGAGACTCG CTCGGTGGGC ACCTGGGTTC GAGAAAGGGA TTTGGGCATT 
CCAGATGGTG AAGCTGCCCT GGTAGCTAAA GTGGCCGTGT TGGAGACCCA GCTCAAAAAA 
GCGCTGCAGG AGCTGCGGGC GGCTCAGACC CAGCAGGTCG ACCTCCAGCC CCAAGCCTGG 
CCACCACCAG ACACCCAGGT CCGCGTGGAC ACCGTGCGAG TTGTGGAGGG TCCCCGGGAA 
GTGGAGGTGG CAGCCAGCAC GGCAGCCGGG GCTCCTGCAC AGCGAGCTCA GAGTCTGGAA 
CCCTATGGAG CAGGGCTGAA GGCCCTGGCC ACATCTGCGG AGAACACCCT TGTGTTCCGA 
AGTCATGAGG TGGTGGAGAC CATGTGTCCC CTGCCCACAG CTTCCACCAG CAACATGCAC 
ACAGCCAAGA AGATCAGTAT TACAGAACGG AATTGCACTG GTGCGGCCAG GATGGCAGAG 
CCTTCCCCCT CTAGTCCATA CCCTGCTGCA GAGCCTGAGA ACCCTGCCCC AGCTGCCCAG 
GACACCACGG ACAGGGAGCT CACCAGGCCT GTGGCATCGC AGGACTCACA AGCGGCCGAG 
GGAGCAGGCG GAGCCTCCTT GGGAGTCCAA TCAGCCTTGA AGAGGAAAGA GGTCCCTGCA 
GACCCTGACG TCCACCAGAG GAACCTTCAG TTTGTGGGCA TCAATGGCGG GTATGAGTCC 
TCCTCGGAAG ACTCCAGCAC AGCAGAGAAC TCGGAACACG AGAGCACAGA GAACGAGGCC 
CCAGAGCCTC CGGTGAGGGT TCTGAGCACA GCTGAAGGCC CTCAGCTCAG GCCTCTGGGG 
CCTGCAGTGG GCAAGACCAG TCAGGACGAG CGTCAGCTCT CTCAGGAATC CCAGCGTGTG 
CCCGAAGCCA AGGTGGCCCC AGGACCTGAC CCCGAGGAGG AGATTCGGAT GGATCTGAGC 
CCTGACCTCA TATCAGCATG CTTGGCCCTG GAGAAATACT TGGAGAACCC CAATGCCCTC 
ACGGAGCGAG AACTGAAAGT GGCTTATACC ACGGTGCTTC AGGAGTGGCT GCGCCTGGCC 
TGCCGCAGTG ATGCACACCC TGAGCTTGTA CGGCGACATC TGGTCACCTT CAGGGCCATG 
TCTGCCCGGC TGCTGGACTA TGTGGTCAAC ATCGCTGACA GCAATGGTAA CACTGCCCTG 
CACTACTCCG TGTCACATGC CAACTTCCCT GTGGTTCGGC AGTTGCTGGA CAGCGGCGTG 
TGTCAGGTGG ACAAGCTAAA CCGTGCTGGC TACAGCCCGA TAATGCTCAC TGCTTTGGCC 
ACCCTGAAGA CCCAGGATGA CATTGACACC ATCCTTCAAC TCTTCCGCCT TGGGAATGTC 
AACGCCAAAG CCAGCCAGGC AGGACAGACG GCCCTGATGC TGGCGGTCAG CCACGGGCGG 
GTGGATGTGG TGAAAGCGCT GTTGGCCTGT GAGGTGGATG TTAACATGCA GGATGAGGAC 
GGCTCCACGG CCCTGATGTG TGCGTGTGAG CACGGACACA AGGAGATCAC CGGGCTCCTG 
CTGGCTGTGC CTAGCTGTGA CATCTCACTC ACCGACCGCG ATGGAAGCAC AGCGCTGATG 
GTAGCCCTCG ACGCTGGGCA GAGCGAGATC GCATCTATGC TGTACTCACG CATGAACATC 
AAGTGCTCCT TCGCTCCCAT GTCAGACTAC GAGAGTCCGG CTTCGTCTTC AGCTGAAGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257342.1
CDS	160..2682
Translation	MAQVLHVPAPFPGTPGQASSAAFPNKEPDPPYSVETPYGYRLDLDFLKYVDDIEKGHTLRRVPVQRRPRLGSLPRGPGSWWTSTESLCSDASGDSRHSAYSYCGRGFYPQYGALETRSGTNPRVERTLLDARRRLEDQAAAPSSGGLGSLTPSAAGSTSSLAGVGLLPPTPRSSGLSTPVAPSAGHLAHVREQMAGALRKLRQLEEQVKLIPVLQVKLSVLQEEKRQLTVQLKSQKFLGHPSGTRSRSELCLDLPEAPDDPAVLETRSVGTWVRERDLGIPDGEAALVAKVAVLETQLKKALQELRAAQTQQVDLQPQAWPPPDTQVRVDTVRVVEGPREVEVAASTAAGAPAQRAQSLEPYGAGLKALATSAENTLVFRSHEVVETMCPLPTASTSNMHTAKKISITERNCTGAARMAEPSPSSPYPAAEPENPAPAAQDTTDRELTRPVASQDSQAAEGAGGASLGVQSALKRKEVPADPDVHQRNLQFVGINGGYESSSEDSSTAENSEHESTENEAPEPPVRVLSTAEGPQLRPLGPAVGKTSQDERQLSQESQRVPEAKVAPGPDPEEEIRMDLSPDLISACLALEKYLENPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVRQLLDSGVCQVDKLNRAGYSPIMLTALATLKTQDDIDTILQLFRLGNVNAKASQAGQTALMLAVSHGRVDVVKALLACEVDVNMQDEDGSTALMCACEHGHKEITGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDYESPASSSAEE

Target ORF information:

RefSeq Version	NM_001270413.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270413.1

ORF Insert Sequence:

ATGGCCCAGG TCCTGCATGT GCCCGCCCCA TTCCCAGGAA CCCCTGGCCA AGCCTCCTCA 
GCGGCCTTCC CCAACAAGGA GCCAGACCCG CCATACTCGG TGGAGACGCC CTATGGCTAC 
CGCCTGGACC TGGACTTTCT TAAGTACGTG GATGACATTG AGAAGGGCCA CACACTGCGC 
AGGGTGCCGG TGCAGCGCCG GCCACGCCTG GGCTCCCTGC CACGTGGCCC GGGCTCCTGG 
TGGACGTCCA CAGAGTCGCT GTGCTCTGAC GCCAGTGGGG ACAGCCGGCA CTCGGCCTAC 
TCCTACTGTG GCCGCGGCTT CTACCCACAG TACGGAGCCT TGGAGACCCG CAGCGGCACC 
AACCCACGCG TGGAACGCAC GCTGCTGGAT GCGCGGCGCC GACTGGAGGA CCAGGCGGCT 
GCCCCATCAT CGGGTGGCCT GGGCTCTCTG ACGCCCAGCG CTGCGGGCTC CACCAGCTCC 
CTGGCAGGCG TGGGCCTGCT GCCCCCCACA CCTCGCAGCT CTGGCTTGTC CACCCCAGTG 
GCACCCAGCG CTGGTCACCT GGCCCACGTG CGCGAACAGA TGGCTGGAGC CCTGCGCAAG 
CTGCGCCAGC TGGAGGAGCA GGTCAAGCTG ATCCCCGTGC TCCAGGTCAA GCTGTCGGTG 
CTCCAGGAGG AAAAAAGACA GCTCACCGTG CAGCTCAAGA GCCAGAAGTT TCTAGGCCAC 
CCCTCAGGGA CAAGGAGCCG GAGCGAGCTC TGCCTGGACC TTCCGGAGGC CCCCGACGAC 
CCTGCTGTGC TAGAGACTCG CTCGGTGGGC ACCTGGGTTC GAGAAAGGGA TTTGGGCATT 
CCAGATGGTG AAGCTGCCCT GGTAGCTAAA GTGGCCGTGT TGGAGACCCA GCTCAAAAAA 
GCGCTGCAGG AGCTGCGGGC GGCTCAGACC CAGCAGGTCG ACCTCCAGCC CCAAGCCTGG 
CCACCACCAG ACACCCAGGT CCGCGTGGAC ACCGTGCGAG TTGTGGAGGG TCCCCGGGAA 
GTGGAGGTGG CAGCCAGCAC GGCAGCCGGG GCTCCTGCAC AGCGAGCTCA GAGTCTGGAA 
CCCTATGGAG CAGGGCTGAA GGCCCTGGCC ACATCTGCGG AGAACACCCT TGTGTTCCGA 
AGTCATGAGG TGGTGGAGAC CATGTGTCCC CTGCCCACAG CTTCCACCAG CAACATGCAC 
ACAGCCAAGA AGATCAGTAT TACAGAACGG AATTGCACTG GTGCGGCCAG GATGGCAGAG 
CCTTCCCCCT CTAGTCCATA CCCTGCTGCA GAGCCTGAGA ACCCTGCCCC AGCTGCCCAG 
GACACCACGG ACAGGGAGCT CACCAGGCCT GTGGCATCGC AGGACTCACA AGCGGCCGAG 
GGAGCAGGCG GAGCCTCCTT GGGAGTCCAA TCAGCCTTGA AGAGGAAAGA GGTCCCTGCA 
GACCCTGACG TCCACCAGAG GAACCTTCAG TTTGTGGGCA TCAATGGCGG GTATGAGTCC 
TCCTCGGAAG ACTCCAGCAC AGCAGAGAAC TCGGAACACG AGAGCACAGA GAACGAGGCC 
CCAGAGCCTC CGGTGAGGGT TCTGAGCACA GCTGAAGGCC CTCAGCTCAG GCCTCTGGGG 
CCTGCAGTGG GCAAGACCAG TCAGGACGAG CGTCAGCTCT CTCAGGAATC CCAGCGTGTG 
CCCGAAGCCA AGGTGGCCCC AGGACCTGAC CCCGAGGAGG AGATTCGGAT GGATCTGAGC 
CCTGACCTCA TATCAGCATG CTTGGCCCTG GAGAAATACT TGGAGAACCC CAATGCCCTC 
ACGGAGCGAG AACTGAAAGT GGCTTATACC ACGGTGCTTC AGGAGTGGCT GCGCCTGGCC 
TGCCGCAGTG ATGCACACCC TGAGCTTGTA CGGCGACATC TGGTCACCTT CAGGGCCATG 
TCTGCCCGGC TGCTGGACTA TGTGGTCAAC ATCGCTGACA GCAATGGTAA CACTGCCCTG 
CACTACTCCG TGTCACATGC CAACTTCCCT GTGGTTCGGC AGTTGCTGGA CAGCGGCGTG 
TGTCAGGTGG ACAAGCTAAA CCGTGCTGGC TACAGCCCGA TAATGCTCAC TGCTTTGGCC 
ACCCTGAAGA CCCAGGATGA CATTGACACC ATCCTTCAAC TCTTCCGCCT TGGGAATGTC 
AACGCCAAAG CCAGCCAGGC AGGACAGACG GCCCTGATGC TGGCGGTCAG CCACGGGCGG 
GTGGATGTGG TGAAAGCGCT GTTGGCCTGT GAGGTGGATG TTAACATGCA GGATGAGGAC 
GGCTCCACGG CCCTGATGTG TGCGTGTGAG CACGGACACA AGGAGATCAC CGGGCTCCTG 
CTGGCTGTGC CTAGCTGTGA CATCTCACTC ACCGACCGCG ATGGAAGCAC AGCGCTGATG 
GTAGCCCTCG ACGCTGGGCA GAGCGAGATC GCATCTATGC TGTACTCACG CATGAACATC 
AAGTGCTCCT TCGCTCCCAT GTCAGACTAC GAGAGTCCGG CTTCGTCTTC AGCTGAAGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kank2 ( XM_006242590.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242652.1 Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa30874
Clone ID Related Accession (Same CDS sequence)	XM_006242590.3 , XM_006242589.3
Accession Version	XM_006242590.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2544bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	KN motif and ankyrin repeat domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242590.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCAGG TCCTGCATGT GCCCGCCCCA TTCCCAGGAA CCCCTGGCCA AGCCTCCTCA 
GCGGCCTTCC CCAACAAGGA GCCAGACCCG CCATACTCGG TGGAGACGCC CTATGGCTAC 
CGCCTGGACC TGGACTTTCT TAAGTACGTG GATGACATTG AGAAGGGCCA CACACTGCGC 
AGGGTGCCGG TGCAGCGCCG GCCACGCCTG GGCTCCCTGC CACGTGGCCC GGGCTCCTGG 
TGGACGTCCA CAGAGTCGCT GTGCTCTGAC GCCAGTGGGG ACAGCCGGCA CTCGGCCTAC 
TCCTACTGTG GCCGCGGCTT CTACCCACAG TACGGAGCCT TGGAGACCCG CAGCGGCACC 
AACCCACGCG TGGAACGCAC GCTGCTGGAT GCGCGGCGCC GACTGGAGGA CCAGGCGGCT 
GCCCCATCAT CGGGTGGCCT GGGCTCTCTG ACGCCCAGCG CTGCGGGCTC CACCAGCTCC 
CTGGCAGGCG TGGGCCTGCT GCCCCCCACA CCTCGCAGCT CTGGCTTGTC CACCCCAGTG 
GCACCCAGCG CTGGTCACCT GGCCCACGTG CGCGAACAGA TGGCTGGAGC CCTGCGCAAG 
CTGCGCCAGC TGGAGGAGCA GGTCAAGCTG ATCCCCGTGC TCCAGGTCAA GCTGTCGGTG 
CTCCAGGAGG AAAAAAGACA GCTCACCGTG CAGCTCAAGA GCCAGAAGTT TCTAGGCCAC 
CCCTCAGGGA CAAGGAGCCG GAGCGAGCTC TGCCTGGACC TTCCGGAGGC CCCCGACGAC 
CCTGCTGTGC TAGAGACTCG CTCGGTGGGC ACCTGGGTTC GAGAAAGGGA TTTGGGCATT 
CCAGATGGTG AAGCTGCCCT GGTAGCTAAA GTGGCCGTGT TGGAGACCCA GCTCAAAAAA 
GCGCTGCAGG AGCTGCGGGC GGCTCAGACC CAGCAGGTCG ACCTCCAGCC CCAAGCCTGG 
CCACCACCAG ACACCCAGGT CCGCGTGGAC ACCGTGCGAG TTGTGGAGGG TCCCCGGGAA 
GTGGAGGTGG CAGCCAGCAC GGCAGCCGGG GCTCCTGCAC AGCGAGCTCA GAGTCTGGAA 
CCCTATGGAG CAGGGCTGAA GGCCCTGGCC ACATCTGCGG AGAACACCCT TGTGTTCCGA 
AGTCATGAGG TGGTGGAGAC CATGTGTCCC CTGCCCACAG CTTCCACCAG CAACATGCAC 
ACAGCCAAGA AGATCAGTAT TACAGAACGG AATTGCACTG GTGCGGCCAG GATGGCAGAC 
CCTCCACCAT CTCCTGCAGA GCCTTCCCCC TCTAGTCCAT ACCCTGCTGC AGAGCCTGAG 
AACCCTGCCC CAGCTGCCCA GGACACCACG GACAGGGAGC TCACCAGGCC TGTGGCATCG 
CAGGACTCAC AAGCGGCCGA GGGAGCAGGC GGAGCCTCCT TGGGAGTCCA ATCAGCCTTG 
AAGAGGAAAG AGGTCCCTGC AGACCCTGAC GTCCACCAGA GGAACCTTCA GTTTGTGGGC 
ATCAATGGCG GGTATGAGTC CTCCTCGGAA GACTCCAGCA CAGCAGAGAA CTCGGAACAC 
GAGAGCACAG AGAACGAGGC CCCAGAGCCT CCGGTGAGGG TTCTGAGCAC AGCTGAAGGC 
CCTCAGCTCA GGCCTCTGGG GCCTGCAGTG GGCAAGACCA GTCAGGACGA GCGTCAGCTC 
TCTCAGGAAT CCCAGCGTGT GCCCGAAGCC AAGGTGGCCC CAGGACCTGA CCCCGAGGAG 
GAGATTCGGA TGGATCTGAG CCCTGACCTC ATATCAGCAT GCTTGGCCCT GGAGAAATAC 
TTGGAGAACC CCAATGCCCT CACGGAGCGA GAACTGAAAG TGGCTTATAC CACGGTGCTT 
CAGGAGTGGC TGCGCCTGGC CTGCCGCAGT GATGCACACC CTGAGCTTGT ACGGCGACAT 
CTGGTCACCT TCAGGGCCAT GTCTGCCCGG CTGCTGGACT ATGTGGTCAA CATCGCTGAC 
AGCAATGGTA ACACTGCCCT GCACTACTCC GTGTCACATG CCAACTTCCC TGTGGTTCGG 
CAGTTGCTGG ACAGCGGCGT GTGTCAGGTG GACAAGCTAA ACCGTGCTGG CTACAGCCCG 
ATAATGCTCA CTGCTTTGGC CACCCTGAAG ACCCAGGATG ACATTGACAC CATCCTTCAA 
CTCTTCCGCC TTGGGAATGT CAACGCCAAA GCCAGCCAGG CAGGACAGAC GGCCCTGATG 
CTGGCGGTCA GCCACGGGCG GGTGGATGTG GTGAAAGCGC TGTTGGCCTG TGAGGTGGAT 
GTTAACATGC AGGATGAGGA CGGCTCCACG GCCCTGATGT GTGCGTGTGA GCACGGACAC 
AAGGAGATCA CCGGGCTCCT GCTGGCTGTG CCTAGCTGTG ACATCTCACT CACCGACCGC 
GATGGAAGCA CAGCGCTGAT GGTAGCCCTC GACGCTGGGC AGAGCGAGAT CGCATCTATG 
CTGTACTCAC GCATGAACAT CAAGTGCTCC TTCGCTCCCA TGTCAGACTA CGAGAGTCCG 
GCTTCGTCTT CAGCTGAAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242652.1
CDS	396..2939
Translation	MAQVLHVPAPFPGTPGQASSAAFPNKEPDPPYSVETPYGYRLDLDFLKYVDDIEKGHTLRRVPVQRRPRLGSLPRGPGSWWTSTESLCSDASGDSRHSAYSYCGRGFYPQYGALETRSGTNPRVERTLLDARRRLEDQAAAPSSGGLGSLTPSAAGSTSSLAGVGLLPPTPRSSGLSTPVAPSAGHLAHVREQMAGALRKLRQLEEQVKLIPVLQVKLSVLQEEKRQLTVQLKSQKFLGHPSGTRSRSELCLDLPEAPDDPAVLETRSVGTWVRERDLGIPDGEAALVAKVAVLETQLKKALQELRAAQTQQVDLQPQAWPPPDTQVRVDTVRVVEGPREVEVAASTAAGAPAQRAQSLEPYGAGLKALATSAENTLVFRSHEVVETMCPLPTASTSNMHTAKKISITERNCTGAARMADPPPSPAEPSPSSPYPAAEPENPAPAAQDTTDRELTRPVASQDSQAAEGAGGASLGVQSALKRKEVPADPDVHQRNLQFVGINGGYESSSEDSSTAENSEHESTENEAPEPPVRVLSTAEGPQLRPLGPAVGKTSQDERQLSQESQRVPEAKVAPGPDPEEEIRMDLSPDLISACLALEKYLENPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVRQLLDSGVCQVDKLNRAGYSPIMLTALATLKTQDDIDTILQLFRLGNVNAKASQAGQTALMLAVSHGRVDVVKALLACEVDVNMQDEDGSTALMCACEHGHKEITGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDYESPASSSAEE

Target ORF information:

RefSeq Version	XM_006242590.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242590.3

ORF Insert Sequence:

ATGGCCCAGG TCCTGCATGT GCCCGCCCCA TTCCCAGGAA CCCCTGGCCA AGCCTCCTCA 
GCGGCCTTCC CCAACAAGGA GCCAGACCCG CCATACTCGG TGGAGACGCC CTATGGCTAC 
CGCCTGGACC TGGACTTTCT TAAGTACGTG GATGACATTG AGAAGGGCCA CACACTGCGC 
AGGGTGCCGG TGCAGCGCCG GCCACGCCTG GGCTCCCTGC CACGTGGCCC GGGCTCCTGG 
TGGACGTCCA CAGAGTCGCT GTGCTCTGAC GCCAGTGGGG ACAGCCGGCA CTCGGCCTAC 
TCCTACTGTG GCCGCGGCTT CTACCCACAG TACGGAGCCT TGGAGACCCG CAGCGGCACC 
AACCCACGCG TGGAACGCAC GCTGCTGGAT GCGCGGCGCC GACTGGAGGA CCAGGCGGCT 
GCCCCATCAT CGGGTGGCCT GGGCTCTCTG ACGCCCAGCG CTGCGGGCTC CACCAGCTCC 
CTGGCAGGCG TGGGCCTGCT GCCCCCCACA CCTCGCAGCT CTGGCTTGTC CACCCCAGTG 
GCACCCAGCG CTGGTCACCT GGCCCACGTG CGCGAACAGA TGGCTGGAGC CCTGCGCAAG 
CTGCGCCAGC TGGAGGAGCA GGTCAAGCTG ATCCCCGTGC TCCAGGTCAA GCTGTCGGTG 
CTCCAGGAGG AAAAAAGACA GCTCACCGTG CAGCTCAAGA GCCAGAAGTT TCTAGGCCAC 
CCCTCAGGGA CAAGGAGCCG GAGCGAGCTC TGCCTGGACC TTCCGGAGGC CCCCGACGAC 
CCTGCTGTGC TAGAGACTCG CTCGGTGGGC ACCTGGGTTC GAGAAAGGGA TTTGGGCATT 
CCAGATGGTG AAGCTGCCCT GGTAGCTAAA GTGGCCGTGT TGGAGACCCA GCTCAAAAAA 
GCGCTGCAGG AGCTGCGGGC GGCTCAGACC CAGCAGGTCG ACCTCCAGCC CCAAGCCTGG 
CCACCACCAG ACACCCAGGT CCGCGTGGAC ACCGTGCGAG TTGTGGAGGG TCCCCGGGAA 
GTGGAGGTGG CAGCCAGCAC GGCAGCCGGG GCTCCTGCAC AGCGAGCTCA GAGTCTGGAA 
CCCTATGGAG CAGGGCTGAA GGCCCTGGCC ACATCTGCGG AGAACACCCT TGTGTTCCGA 
AGTCATGAGG TGGTGGAGAC CATGTGTCCC CTGCCCACAG CTTCCACCAG CAACATGCAC 
ACAGCCAAGA AGATCAGTAT TACAGAACGG AATTGCACTG GTGCGGCCAG GATGGCAGAC 
CCTCCACCAT CTCCTGCAGA GCCTTCCCCC TCTAGTCCAT ACCCTGCTGC AGAGCCTGAG 
AACCCTGCCC CAGCTGCCCA GGACACCACG GACAGGGAGC TCACCAGGCC TGTGGCATCG 
CAGGACTCAC AAGCGGCCGA GGGAGCAGGC GGAGCCTCCT TGGGAGTCCA ATCAGCCTTG 
AAGAGGAAAG AGGTCCCTGC AGACCCTGAC GTCCACCAGA GGAACCTTCA GTTTGTGGGC 
ATCAATGGCG GGTATGAGTC CTCCTCGGAA GACTCCAGCA CAGCAGAGAA CTCGGAACAC 
GAGAGCACAG AGAACGAGGC CCCAGAGCCT CCGGTGAGGG TTCTGAGCAC AGCTGAAGGC 
CCTCAGCTCA GGCCTCTGGG GCCTGCAGTG GGCAAGACCA GTCAGGACGA GCGTCAGCTC 
TCTCAGGAAT CCCAGCGTGT GCCCGAAGCC AAGGTGGCCC CAGGACCTGA CCCCGAGGAG 
GAGATTCGGA TGGATCTGAG CCCTGACCTC ATATCAGCAT GCTTGGCCCT GGAGAAATAC 
TTGGAGAACC CCAATGCCCT CACGGAGCGA GAACTGAAAG TGGCTTATAC CACGGTGCTT 
CAGGAGTGGC TGCGCCTGGC CTGCCGCAGT GATGCACACC CTGAGCTTGT ACGGCGACAT 
CTGGTCACCT TCAGGGCCAT GTCTGCCCGG CTGCTGGACT ATGTGGTCAA CATCGCTGAC 
AGCAATGGTA ACACTGCCCT GCACTACTCC GTGTCACATG CCAACTTCCC TGTGGTTCGG 
CAGTTGCTGG ACAGCGGCGT GTGTCAGGTG GACAAGCTAA ACCGTGCTGG CTACAGCCCG 
ATAATGCTCA CTGCTTTGGC CACCCTGAAG ACCCAGGATG ACATTGACAC CATCCTTCAA 
CTCTTCCGCC TTGGGAATGT CAACGCCAAA GCCAGCCAGG CAGGACAGAC GGCCCTGATG 
CTGGCGGTCA GCCACGGGCG GGTGGATGTG GTGAAAGCGC TGTTGGCCTG TGAGGTGGAT 
GTTAACATGC AGGATGAGGA CGGCTCCACG GCCCTGATGT GTGCGTGTGA GCACGGACAC 
AAGGAGATCA CCGGGCTCCT GCTGGCTGTG CCTAGCTGTG ACATCTCACT CACCGACCGC 
GATGGAAGCA CAGCGCTGAT GGTAGCCCTC GACGCTGGGC AGAGCGAGAT CGCATCTATG 
CTGTACTCAC GCATGAACAT CAAGTGCTCC TTCGCTCCCA TGTCAGACTA CGAGAGTCCG 
GCTTCGTCTT CAGCTGAAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kank2 ( XM_006242589.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242651.1 Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), transcript variant X1, mRNA.

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CloneID	ORa30874
Clone ID Related Accession (Same CDS sequence)	XM_006242590.3 , XM_006242589.3
Accession Version	XM_006242589.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2544bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	KN motif and ankyrin repeat domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242589.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCAGG TCCTGCATGT GCCCGCCCCA TTCCCAGGAA CCCCTGGCCA AGCCTCCTCA 
GCGGCCTTCC CCAACAAGGA GCCAGACCCG CCATACTCGG TGGAGACGCC CTATGGCTAC 
CGCCTGGACC TGGACTTTCT TAAGTACGTG GATGACATTG AGAAGGGCCA CACACTGCGC 
AGGGTGCCGG TGCAGCGCCG GCCACGCCTG GGCTCCCTGC CACGTGGCCC GGGCTCCTGG 
TGGACGTCCA CAGAGTCGCT GTGCTCTGAC GCCAGTGGGG ACAGCCGGCA CTCGGCCTAC 
TCCTACTGTG GCCGCGGCTT CTACCCACAG TACGGAGCCT TGGAGACCCG CAGCGGCACC 
AACCCACGCG TGGAACGCAC GCTGCTGGAT GCGCGGCGCC GACTGGAGGA CCAGGCGGCT 
GCCCCATCAT CGGGTGGCCT GGGCTCTCTG ACGCCCAGCG CTGCGGGCTC CACCAGCTCC 
CTGGCAGGCG TGGGCCTGCT GCCCCCCACA CCTCGCAGCT CTGGCTTGTC CACCCCAGTG 
GCACCCAGCG CTGGTCACCT GGCCCACGTG CGCGAACAGA TGGCTGGAGC CCTGCGCAAG 
CTGCGCCAGC TGGAGGAGCA GGTCAAGCTG ATCCCCGTGC TCCAGGTCAA GCTGTCGGTG 
CTCCAGGAGG AAAAAAGACA GCTCACCGTG CAGCTCAAGA GCCAGAAGTT TCTAGGCCAC 
CCCTCAGGGA CAAGGAGCCG GAGCGAGCTC TGCCTGGACC TTCCGGAGGC CCCCGACGAC 
CCTGCTGTGC TAGAGACTCG CTCGGTGGGC ACCTGGGTTC GAGAAAGGGA TTTGGGCATT 
CCAGATGGTG AAGCTGCCCT GGTAGCTAAA GTGGCCGTGT TGGAGACCCA GCTCAAAAAA 
GCGCTGCAGG AGCTGCGGGC GGCTCAGACC CAGCAGGTCG ACCTCCAGCC CCAAGCCTGG 
CCACCACCAG ACACCCAGGT CCGCGTGGAC ACCGTGCGAG TTGTGGAGGG TCCCCGGGAA 
GTGGAGGTGG CAGCCAGCAC GGCAGCCGGG GCTCCTGCAC AGCGAGCTCA GAGTCTGGAA 
CCCTATGGAG CAGGGCTGAA GGCCCTGGCC ACATCTGCGG AGAACACCCT TGTGTTCCGA 
AGTCATGAGG TGGTGGAGAC CATGTGTCCC CTGCCCACAG CTTCCACCAG CAACATGCAC 
ACAGCCAAGA AGATCAGTAT TACAGAACGG AATTGCACTG GTGCGGCCAG GATGGCAGAC 
CCTCCACCAT CTCCTGCAGA GCCTTCCCCC TCTAGTCCAT ACCCTGCTGC AGAGCCTGAG 
AACCCTGCCC CAGCTGCCCA GGACACCACG GACAGGGAGC TCACCAGGCC TGTGGCATCG 
CAGGACTCAC AAGCGGCCGA GGGAGCAGGC GGAGCCTCCT TGGGAGTCCA ATCAGCCTTG 
AAGAGGAAAG AGGTCCCTGC AGACCCTGAC GTCCACCAGA GGAACCTTCA GTTTGTGGGC 
ATCAATGGCG GGTATGAGTC CTCCTCGGAA GACTCCAGCA CAGCAGAGAA CTCGGAACAC 
GAGAGCACAG AGAACGAGGC CCCAGAGCCT CCGGTGAGGG TTCTGAGCAC AGCTGAAGGC 
CCTCAGCTCA GGCCTCTGGG GCCTGCAGTG GGCAAGACCA GTCAGGACGA GCGTCAGCTC 
TCTCAGGAAT CCCAGCGTGT GCCCGAAGCC AAGGTGGCCC CAGGACCTGA CCCCGAGGAG 
GAGATTCGGA TGGATCTGAG CCCTGACCTC ATATCAGCAT GCTTGGCCCT GGAGAAATAC 
TTGGAGAACC CCAATGCCCT CACGGAGCGA GAACTGAAAG TGGCTTATAC CACGGTGCTT 
CAGGAGTGGC TGCGCCTGGC CTGCCGCAGT GATGCACACC CTGAGCTTGT ACGGCGACAT 
CTGGTCACCT TCAGGGCCAT GTCTGCCCGG CTGCTGGACT ATGTGGTCAA CATCGCTGAC 
AGCAATGGTA ACACTGCCCT GCACTACTCC GTGTCACATG CCAACTTCCC TGTGGTTCGG 
CAGTTGCTGG ACAGCGGCGT GTGTCAGGTG GACAAGCTAA ACCGTGCTGG CTACAGCCCG 
ATAATGCTCA CTGCTTTGGC CACCCTGAAG ACCCAGGATG ACATTGACAC CATCCTTCAA 
CTCTTCCGCC TTGGGAATGT CAACGCCAAA GCCAGCCAGG CAGGACAGAC GGCCCTGATG 
CTGGCGGTCA GCCACGGGCG GGTGGATGTG GTGAAAGCGC TGTTGGCCTG TGAGGTGGAT 
GTTAACATGC AGGATGAGGA CGGCTCCACG GCCCTGATGT GTGCGTGTGA GCACGGACAC 
AAGGAGATCA CCGGGCTCCT GCTGGCTGTG CCTAGCTGTG ACATCTCACT CACCGACCGC 
GATGGAAGCA CAGCGCTGAT GGTAGCCCTC GACGCTGGGC AGAGCGAGAT CGCATCTATG 
CTGTACTCAC GCATGAACAT CAAGTGCTCC TTCGCTCCCA TGTCAGACTA CGAGAGTCCG 
GCTTCGTCTT CAGCTGAAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242651.1
CDS	541..3084
Translation	MAQVLHVPAPFPGTPGQASSAAFPNKEPDPPYSVETPYGYRLDLDFLKYVDDIEKGHTLRRVPVQRRPRLGSLPRGPGSWWTSTESLCSDASGDSRHSAYSYCGRGFYPQYGALETRSGTNPRVERTLLDARRRLEDQAAAPSSGGLGSLTPSAAGSTSSLAGVGLLPPTPRSSGLSTPVAPSAGHLAHVREQMAGALRKLRQLEEQVKLIPVLQVKLSVLQEEKRQLTVQLKSQKFLGHPSGTRSRSELCLDLPEAPDDPAVLETRSVGTWVRERDLGIPDGEAALVAKVAVLETQLKKALQELRAAQTQQVDLQPQAWPPPDTQVRVDTVRVVEGPREVEVAASTAAGAPAQRAQSLEPYGAGLKALATSAENTLVFRSHEVVETMCPLPTASTSNMHTAKKISITERNCTGAARMADPPPSPAEPSPSSPYPAAEPENPAPAAQDTTDRELTRPVASQDSQAAEGAGGASLGVQSALKRKEVPADPDVHQRNLQFVGINGGYESSSEDSSTAENSEHESTENEAPEPPVRVLSTAEGPQLRPLGPAVGKTSQDERQLSQESQRVPEAKVAPGPDPEEEIRMDLSPDLISACLALEKYLENPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVRQLLDSGVCQVDKLNRAGYSPIMLTALATLKTQDDIDTILQLFRLGNVNAKASQAGQTALMLAVSHGRVDVVKALLACEVDVNMQDEDGSTALMCACEHGHKEITGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDYESPASSSAEE

Target ORF information:

RefSeq Version	XM_006242589.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus KN motif and ankyrin repeat domains 2 (Kank2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242589.3

ORF Insert Sequence:

ATGGCCCAGG TCCTGCATGT GCCCGCCCCA TTCCCAGGAA CCCCTGGCCA AGCCTCCTCA 
GCGGCCTTCC CCAACAAGGA GCCAGACCCG CCATACTCGG TGGAGACGCC CTATGGCTAC 
CGCCTGGACC TGGACTTTCT TAAGTACGTG GATGACATTG AGAAGGGCCA CACACTGCGC 
AGGGTGCCGG TGCAGCGCCG GCCACGCCTG GGCTCCCTGC CACGTGGCCC GGGCTCCTGG 
TGGACGTCCA CAGAGTCGCT GTGCTCTGAC GCCAGTGGGG ACAGCCGGCA CTCGGCCTAC 
TCCTACTGTG GCCGCGGCTT CTACCCACAG TACGGAGCCT TGGAGACCCG CAGCGGCACC 
AACCCACGCG TGGAACGCAC GCTGCTGGAT GCGCGGCGCC GACTGGAGGA CCAGGCGGCT 
GCCCCATCAT CGGGTGGCCT GGGCTCTCTG ACGCCCAGCG CTGCGGGCTC CACCAGCTCC 
CTGGCAGGCG TGGGCCTGCT GCCCCCCACA CCTCGCAGCT CTGGCTTGTC CACCCCAGTG 
GCACCCAGCG CTGGTCACCT GGCCCACGTG CGCGAACAGA TGGCTGGAGC CCTGCGCAAG 
CTGCGCCAGC TGGAGGAGCA GGTCAAGCTG ATCCCCGTGC TCCAGGTCAA GCTGTCGGTG 
CTCCAGGAGG AAAAAAGACA GCTCACCGTG CAGCTCAAGA GCCAGAAGTT TCTAGGCCAC 
CCCTCAGGGA CAAGGAGCCG GAGCGAGCTC TGCCTGGACC TTCCGGAGGC CCCCGACGAC 
CCTGCTGTGC TAGAGACTCG CTCGGTGGGC ACCTGGGTTC GAGAAAGGGA TTTGGGCATT 
CCAGATGGTG AAGCTGCCCT GGTAGCTAAA GTGGCCGTGT TGGAGACCCA GCTCAAAAAA 
GCGCTGCAGG AGCTGCGGGC GGCTCAGACC CAGCAGGTCG ACCTCCAGCC CCAAGCCTGG 
CCACCACCAG ACACCCAGGT CCGCGTGGAC ACCGTGCGAG TTGTGGAGGG TCCCCGGGAA 
GTGGAGGTGG CAGCCAGCAC GGCAGCCGGG GCTCCTGCAC AGCGAGCTCA GAGTCTGGAA 
CCCTATGGAG CAGGGCTGAA GGCCCTGGCC ACATCTGCGG AGAACACCCT TGTGTTCCGA 
AGTCATGAGG TGGTGGAGAC CATGTGTCCC CTGCCCACAG CTTCCACCAG CAACATGCAC 
ACAGCCAAGA AGATCAGTAT TACAGAACGG AATTGCACTG GTGCGGCCAG GATGGCAGAC 
CCTCCACCAT CTCCTGCAGA GCCTTCCCCC TCTAGTCCAT ACCCTGCTGC AGAGCCTGAG 
AACCCTGCCC CAGCTGCCCA GGACACCACG GACAGGGAGC TCACCAGGCC TGTGGCATCG 
CAGGACTCAC AAGCGGCCGA GGGAGCAGGC GGAGCCTCCT TGGGAGTCCA ATCAGCCTTG 
AAGAGGAAAG AGGTCCCTGC AGACCCTGAC GTCCACCAGA GGAACCTTCA GTTTGTGGGC 
ATCAATGGCG GGTATGAGTC CTCCTCGGAA GACTCCAGCA CAGCAGAGAA CTCGGAACAC 
GAGAGCACAG AGAACGAGGC CCCAGAGCCT CCGGTGAGGG TTCTGAGCAC AGCTGAAGGC 
CCTCAGCTCA GGCCTCTGGG GCCTGCAGTG GGCAAGACCA GTCAGGACGA GCGTCAGCTC 
TCTCAGGAAT CCCAGCGTGT GCCCGAAGCC AAGGTGGCCC CAGGACCTGA CCCCGAGGAG 
GAGATTCGGA TGGATCTGAG CCCTGACCTC ATATCAGCAT GCTTGGCCCT GGAGAAATAC 
TTGGAGAACC CCAATGCCCT CACGGAGCGA GAACTGAAAG TGGCTTATAC CACGGTGCTT 
CAGGAGTGGC TGCGCCTGGC CTGCCGCAGT GATGCACACC CTGAGCTTGT ACGGCGACAT 
CTGGTCACCT TCAGGGCCAT GTCTGCCCGG CTGCTGGACT ATGTGGTCAA CATCGCTGAC 
AGCAATGGTA ACACTGCCCT GCACTACTCC GTGTCACATG CCAACTTCCC TGTGGTTCGG 
CAGTTGCTGG ACAGCGGCGT GTGTCAGGTG GACAAGCTAA ACCGTGCTGG CTACAGCCCG 
ATAATGCTCA CTGCTTTGGC CACCCTGAAG ACCCAGGATG ACATTGACAC CATCCTTCAA 
CTCTTCCGCC TTGGGAATGT CAACGCCAAA GCCAGCCAGG CAGGACAGAC GGCCCTGATG 
CTGGCGGTCA GCCACGGGCG GGTGGATGTG GTGAAAGCGC TGTTGGCCTG TGAGGTGGAT 
GTTAACATGC AGGATGAGGA CGGCTCCACG GCCCTGATGT GTGCGTGTGA GCACGGACAC 
AAGGAGATCA CCGGGCTCCT GCTGGCTGTG CCTAGCTGTG ACATCTCACT CACCGACCGC 
GATGGAAGCA CAGCGCTGAT GGTAGCCCTC GACGCTGGGC AGAGCGAGAT CGCATCTATG 
CTGTACTCAC GCATGAACAT CAAGTGCTCC TTCGCTCCCA TGTCAGACTA CGAGAGTCCG 
GCTTCGTCTT CAGCTGAAGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
The Journal of clinical investigation125(6)2375-84(2015 Jun)
Gee HY,Zhang F,Ashraf S,Kohl S,Sadowski CE,Vega-Warner V,Zhou W,Lovric S,Fang H,Nettleton M,Zhu JY,Hoefele J,Weber LT,Podracka L,Boor A,Fehrenbach H,Innis JW,Washburn J,Levy S,Lifton RP,Otto EA,Han Z,Hildebrandt F

Mutation in KANK2, encoding a sequestering protein for steroid receptor coactivators, causes keratoderma and woolly hair.
Journal of medical genetics51(6)388-94(2014 Jun)
Ramot Y,Molho-Pessach V,Meir T,Alper-Pinus R,Siam I,Tams S,Babay S,Zlotogorski A

Steroid receptor coactivator-interacting protein (SIP) inhibits caspase-independent apoptosis by preventing apoptosis-inducing factor (AIF) from being released from mitochondria.
The Journal of biological chemistry287(16)12612-21(2012 Apr)
Wang D,Liang J,Zhang Y,Gui B,Wang F,Yi X,Sun L,Yao Z,Shang Y

SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.
The EMBO journal26(11)2645-57(2007 Jun)
Zhang Y,Zhang H,Liang J,Yu W,Shang Y

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Kank2 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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