FSHB cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	FSHB
Entrez Gene ID	443387
Full Name	follicle stimulating hormone beta subunit
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009798.1	NP_001009798.1	follitropin subunit beta precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Effect of phytoestrogens on basal and GnRH-induced gonadotropin secretion.
Arispe SA, Adams B, Adams TE
The Journal of endocrinology219(3)243-50(2013 Dec)

Gonadotrope-specific expression and regulation of ovine follicle stimulating hormone Beta: transgenic and adenoviral approaches using primary murine gonadotropes.
Jia J, Shafiee-Kermani F, Miller WL
PloS one8(7)e66852(2013)

Expression and regulation of the beta-subunit of ovine follicle-stimulating hormone relies heavily on a promoter sequence likely to bind Smad-associated proteins.
Su P, Shafiee-Kermani F, Gore AJ, Jia J, Wu JC, Miller WL
Endocrinology148(9)4500-8(2007 Sep)

Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression.
Safwat N, Ninomiya-Tsuji J, Gore AJ, Miller WL
Endocrinology146(11)4814-24(2005 Nov)

Effects of intracerebroventricular infusion of genistein on gonadotrophin subunit mRNA and immunoreactivity of gonadotrophins and oestrogen receptor-alpha in the pituitary cells of the anoestrous ewe.
Polkowska J, Ridderstråle Y, Wańkowska M, Romanowicz K, Misztal T, Madej A
Journal of chemical neuroanatomy28(4)217-24(2004 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following FSHB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FSHB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSm00003	NM_001009798.1 Latest version!	Ovis aries follicle stimulating hormone subunit beta (FSHB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FSHB ( NM_001009798.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001009798.1 Ovis aries follicle stimulating hormone subunit beta (FSHB), mRNA.

Price & Availability↑

CloneID	OSm00003
Clone ID Related Accession (Same CDS sequence)	NM_001009798.1
Accession Version	NM_001009798.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Ovis aries(sheep)
Product	follitropin subunit beta precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X15493.1. ##Evidence-Data-START## Transcript exon combination :: X15493.1 [ECO:0000332] ##Evidence-Data-END##

ATGAAGTCCG TCCAGTTCTG CTTCCTTTTC TGTTGCTGGA GAGCAATCTG CTGCAGAAGC 
TGCGAGCTGA CCAACATCAC CATCACGGTG GAGAAAGAGG AATGTAGCTT CTGCATAAGC 
ATCAACACCA CGTGGTGTGC AGGCTATTGC TACACCCGGG ACTTGGTGTA CAAGGACCCA 
GCGAGGCCCA ACATCCAGAA AGCATGTACC TTCAAGGAGC TGGTGTACGA GACGGTGAAA 
GTGCCTGGCT GTGCCCACCA TGCAGACTCC CTGTACACGT ACCCAGTAGC CACTGAATGT 
CACTGCGGCA AGTGTGACCG CGACAGCACT GACTGCACCG TGCGAGGCCT GGGGCCCAGC 
TACTGCTCCT TCAGTGACAT CAGAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009798.1
CDS	56..445
Translation	MKSVQFCFLFCCWRAICCRSCELTNITITVEKEECSFCISINTTWCAGYCYTRDLVYKDPARPNIQKACTFKELVYETVKVPGCAHHADSLYTYPVATECHCGKCDRDSTDCTVRGLGPSYCSFSDIRE

Target ORF information:

RefSeq Version	NM_001009798.1
Organism	Ovis aries(sheep)
Definition	Ovis aries follicle stimulating hormone subunit beta (FSHB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009798.1

ORF Insert Sequence:

ATGAAGTCCG TCCAGTTCTG CTTCCTTTTC TGTTGCTGGA GAGCAATCTG CTGCAGAAGC 
TGCGAGCTGA CCAACATCAC CATCACGGTG GAGAAAGAGG AATGTAGCTT CTGCATAAGC 
ATCAACACCA CGTGGTGTGC AGGCTATTGC TACACCCGGG ACTTGGTGTA CAAGGACCCA 
GCGAGGCCCA ACATCCAGAA AGCATGTACC TTCAAGGAGC TGGTGTACGA GACGGTGAAA 
GTGCCTGGCT GTGCCCACCA TGCAGACTCC CTGTACACGT ACCCAGTAGC CACTGAATGT 
CACTGCGGCA AGTGTGACCG CGACAGCACT GACTGCACCG TGCGAGGCCT GGGGCCCAGC 
TACTGCTCCT TCAGTGACAT CAGAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of phytoestrogens on basal and GnRH-induced gonadotropin secretion.
The Journal of endocrinology219(3)243-50(2013 Dec)
Arispe SA,Adams B,Adams TE

Gonadotrope-specific expression and regulation of ovine follicle stimulating hormone Beta: transgenic and adenoviral approaches using primary murine gonadotropes.
PloS one8(7)e66852(2013)
Jia J,Shafiee-Kermani F,Miller WL

Expression and regulation of the beta-subunit of ovine follicle-stimulating hormone relies heavily on a promoter sequence likely to bind Smad-associated proteins.
Endocrinology148(9)4500-8(2007 Sep)
Su P,Shafiee-Kermani F,Gore AJ,Jia J,Wu JC,Miller WL

Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression.
Endocrinology146(11)4814-24(2005 Nov)
Safwat N,Ninomiya-Tsuji J,Gore AJ,Miller WL

Effects of intracerebroventricular infusion of genistein on gonadotrophin subunit mRNA and immunoreactivity of gonadotrophins and oestrogen receptor-alpha in the pituitary cells of the anoestrous ewe.
Journal of chemical neuroanatomy28(4)217-24(2004 Dec)
Polkowska J,Ridderstråle Y,Wańkowska M,Romanowicz K,Misztal T,Madej A