ATP2A2 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATP2A2
Entrez Gene ID	100038308
Full Name	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Synonyms	SERCA2
Gene Type	protein-coding
Organism	Oryctolagus cuniculus(rabbit)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001089321.1	NP_001082790.1	sarcoplasmic/endoplasmic reticulum calcium ATPase 2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Pulmonary artery banding alters the expression of Ca2+ transport proteins in the right atrium in rabbits.
Gupta SC, Varian KD, Bal NC, Abraham JL, Periasamy M, Janssen PM
American journal of physiology. Heart and circulatory physiology296(6)H1933-9(2009 Jun)

Regulation of fast skeletal muscle activity by SERCA1 vicinal-cysteines.
Alvarez R, Vázquez P, Pérez F, Jiménez A, Tirado A, Irles C, González-Serratos H, Ortega A
Journal of muscle research and cell motility30(1-2)5-16(2009)

Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and sarcoplasmic reticulum Ca2+ ATPase isoform 1 heat production.
Arruda AP, Ketzer LA, Nigro M, Galina A, Carvalho DP, de Meis L
Endocrinology149(12)6262-71(2008 Dec)

How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump.
Toyoshima C, Norimatsu Y, Iwasawa S, Tsuda T, Ogawa H
Proceedings of the National Academy of Sciences of the United States of America104(50)19831-6(2007 Dec)

Amino-acid sequence of a Ca2+ + Mg2+-dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence.
MacLennan DH, Brandl CJ, Korczak B, Green NM
Nature316(6030)696-700(1985 Aug 22-28)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ATP2A2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP2A2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OOb00386	NM_001089321.1 Latest version!	Oryctolagus cuniculus ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATP2A2 ( NM_001089321.1 ) cDNA ORF clone, Oryctolagus cuniculus(rabbit) -> NP_001082790.1 Oryctolagus cuniculus ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2), mRNA.

Price & Availability↑

CloneID	OOb00386
Clone ID Related Accession (Same CDS sequence)	NM_001089321.1
Accession Version	NM_001089321.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3129bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564761600000
Organism	Oryctolagus cuniculus(rabbit)
Product	sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J04703.1. On Sep 21, 2010 this sequence version replaced NM_001089320.1. ##Evidence-Data-START## Transcript exon combination :: J04703.1, X52496.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1876818, SAMEA1876819 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAACG CGCACACAAA GACGGTGGAG GAGGTGCTGG GCCACTTCGG CGTCAACGAG 
AGCACGGGGC TGAGCCTGGA GCAGGTCAAG AAGCTCAAGG AGAGATGGGG CTCCAACGAG 
TTACCGGCTG AAGAAGGAAA AACCTTGCTG GAACTTGTGA TTGAGCAATT TGAAGATTTA 
CTAGTTAGAA TTTTATTGCT GGCAGCATGT ATATCTTTTG TTTTGGCTTG GTTTGAAGAA 
GGTGAAGAAA CCATTACAGC CTTTGTAGAA CCTTTTGTAA TTCTGCTTAT ATTGGTAGCC 
AATGCCATCG TGGGTGTATG GCAGGAAAGG AATGCTGAAA ATGCAATTGA AGCCCTTAAG 
GAGTATGAGC CTGAAATGGG CAAAGTGTAT CGGCAGGACA GAAAGAGTGT ACAGCGCATT 
AAAGCTAAAG ACATCGTTCC TGGTGATATT GTAGAAATCG CAGTTGGTGA CAAAGTTCCT 
GCCGACATAA GATTGACTTC TATCAAGTCT ACAACTCTAA GAGTTGACCA GTCAATTCTC 
ACAGGTGAAT CTGTCTCTGT CATCAAGCAC ACTGACCCTG TCCCAGACCC GCGGGCTGTC 
AACCAGGATA AGAAGAACAT GCTTTTTTCT GGCACAAACA TTGCTGCAGG GAAAGCCATG 
GGAGTGGTGG TGGCAACTGG AGTCAACACT GAGATTGGCA AGATTCGGGA TGAGATGGTG 
GCGACAGAAC AGGAGAGGAC GCCTCTTCAG CAGAAACTAG ATGAATTCGG AGAACAGCTT 
TCCAAAGTCA TCTCCCTTAT TTGCATTGCA GTCTGGATCA TAAACATTGG GCATTTCAAT 
GACCCAGTTC ATGGAGGCTC CTGGATTAGA GGTGCTATTT ACTACTTTAA GATTGCAGTG 
GCCCTGGCGG TAGCAGCTAT TCCTGAAGGT CTGCCTGCCG TCATCACCAC CTGCCTGGCT 
CTTGGAACTC GCAGGATGGC AAAGAAAAAC GCCATCGTCC GAAGCCTGCC TTCTGTGGAA 
ACCCTCGGCT GCACTTCTGT GATCTGCTCT GACAAGACTG GCACACTCAC AACAAACCAG 
ATGTCAGTCT GCAGGATGTT CATCCTGGAC AAGGTTGATG GTGATACTTG TTCCCTGAAT 
GAGTTCACCA TAACTGGATC AACGTACGCA CCTATTGGAG AAGTGCATAA AGATGATAAA 
CCAGTGAAGT GTCATCAGTA TGATGGTCTT GTAGAATTAG CAACAATTTG TGCTCTTTGT 
AATGACTCTG CTTTGGATTA CAATGAGGCC AAAGGTGTGT ATGAAAAGGT TGGAGAAGCT 
ACAGAGACTG CCCTGACGTG CCTGGTGGAG AAGATGAACG TGTTTGACAC TGAATTGAAG 
GGTCTCTCTA AAATAGAGCG CGCGAATGCC TGCAACTCGG TCATTAAGCA GCTGATGAAA 
AAGGAATTCA CTCTAGAATT TTCACGTGAT AGAAAATCAA TGTCAGTGTA TTGTACGCCA 
AACAAACCAA GCCGGACGTC CATGAGCAAG ATGTTTGTGA AGGGTGCTCC TGAGGGTGTC 
ATCGACAGGT GCACCCACAT TCGGGTTGGA AGTACCAAGG TCCCCATGAC AGCTGGAGTC 
AAGCAGAAGA TCATGTCTGT CATTCGGGAA TGGGGTAGTG GCAGCGACAC ACTGCGGTGC 
CTGGCCCTGG CCACTCACGA CAACCCACTG AGAAGAGAAG AAATGCACCT GGAGGACTCT 
GCCAACTTTA TTAAGTATGA GACCAACCTG ACTTTTGTTG GCTGCGTGGG CATGCTGGAT 
CCTCCCAGGA TTGAGGTGGC CTCCTCCGTG AAGCTGTGCC GGCAAGCAGG CATCCGGGTC 
ATCATGATCA CCGGGGACAA CAAGGGTACT GCCGTAGCCA TCTGTCGCCG CATTGGCATC 
TTTGGTCAGG AGGAGGATGT GACGGCCAAG GCTTTCACAG GCCGGGAGTT TGACGAACTC 
AACCCCTCAG CCCAGCGAGA TGCTTGCCTA AATGCCCGCT GCTTTGCTCG AGTTGAACCT 
TCCCACAAGT CCAAGATCGT AGAATTTCTT CAGTCCTTTG ATGAGATCAC AGCTATGACT 
GGCGACGGTG TGAATGATGC CCCTGCTCTG AAGAAAGCGG AGATTGGCAT TGCCATGGGC 
TCTGGCACCG CGGTGGCTAA AACTGCCTCT GAGATGGTCC TGGCTGATGA CAACTTCTCC 
ACCATTGTGG CTGCTGTGGA GGAGGGGCGG GCCATCTACA ACAACATGAA GCAGTTCATC 
CGCTACCTCA TCTCCTCCAA CGTGGGGGAG GTTGTCTGCA TTTTCCTGAC GGCAGCCCTT 
GGGTTTCCTG AGGCCCTGAT TCCCGTGCAG CTGCTCTGGG TCAATCTGGT GACAGATGGC 
CTGCCTGCCA CCGCGCTGGG CTTCAACCCT CCGGATCTGG ACATCATGAA TAAACCGCCT 
CGGAACCCAA AGGAACCACT GATCAGCGGG TGGCTCTTTT TCCGTTACCT GGCTATTGGC 
TGTTACGTTG GCGCCGCGAC AGTGGGTGCT GCTGCGTGGT GGTTCATTGC TGCCGATGGT 
GGTCCAAGAG TGTCCTTCTA CCAGCTGAGT CACTTCCTGC AGTGTAAAGA GGACAACCCG 
GACTTCGAGG GCGTGGATTG TGCAATCTTT GAGTCTCCAT ATCCCATGAC AATGGCACTG 
TCTGTTCTGG TCACCATAGA GATGTGCAAC GCCCTCAACA GCCTGTCTGA AAACCAGTCC 
TTGCTGCGGA TGCCGCCCTG GGAGAACATC TGGCTGGTGG GCTCCATCTG CCTGTCCATG 
TCACTGCACT TCCTCATCCT CTACGTCGAG CCCCTGCCGC TTATCTTCCA GATCACACCG 
CTGAATGTGA CCCAGTGGCT GATGGTGCTG AAAATCTCCT TACCTGTGAT TCTCATGGAC 
GAGACTCTCA AGTTCGTGGC CCGCAACTAC CTGGAACCTG GTAAAGAGTG TGTGCAGCCT 
GCCCCCCAGT CCTGCTCGTT GTGGGCGTGC ACCGAGGGGG TCTCCTGGCC GTTTGTGCTG 
CTCATAGTGC CCCTGGTGAT GTGGGTCTAC AGCACCGACA CTAACTTCAG CGATCTGCTC 
TGGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001082790.1
CDS	193..3321
Translation	MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVDGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTAGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQEEDVTAKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPAPQSCSLWACTEGVSWPFVLLIVPLVMWVYSTDTNFSDLLWS

Target ORF information:

RefSeq Version	NM_001089321.1
Organism	Oryctolagus cuniculus(rabbit)
Definition	Oryctolagus cuniculus ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001089321.1

ORF Insert Sequence:

ATGGAGAACG CGCACACAAA GACGGTGGAG GAGGTGCTGG GCCACTTCGG CGTCAACGAG 
AGCACGGGGC TGAGCCTGGA GCAGGTCAAG AAGCTCAAGG AGAGATGGGG CTCCAACGAG 
TTACCGGCTG AAGAAGGAAA AACCTTGCTG GAACTTGTGA TTGAGCAATT TGAAGATTTA 
CTAGTTAGAA TTTTATTGCT GGCAGCATGT ATATCTTTTG TTTTGGCTTG GTTTGAAGAA 
GGTGAAGAAA CCATTACAGC CTTTGTAGAA CCTTTTGTAA TTCTGCTTAT ATTGGTAGCC 
AATGCCATCG TGGGTGTATG GCAGGAAAGG AATGCTGAAA ATGCAATTGA AGCCCTTAAG 
GAGTATGAGC CTGAAATGGG CAAAGTGTAT CGGCAGGACA GAAAGAGTGT ACAGCGCATT 
AAAGCTAAAG ACATCGTTCC TGGTGATATT GTAGAAATCG CAGTTGGTGA CAAAGTTCCT 
GCCGACATAA GATTGACTTC TATCAAGTCT ACAACTCTAA GAGTTGACCA GTCAATTCTC 
ACAGGTGAAT CTGTCTCTGT CATCAAGCAC ACTGACCCTG TCCCAGACCC GCGGGCTGTC 
AACCAGGATA AGAAGAACAT GCTTTTTTCT GGCACAAACA TTGCTGCAGG GAAAGCCATG 
GGAGTGGTGG TGGCAACTGG AGTCAACACT GAGATTGGCA AGATTCGGGA TGAGATGGTG 
GCGACAGAAC AGGAGAGGAC GCCTCTTCAG CAGAAACTAG ATGAATTCGG AGAACAGCTT 
TCCAAAGTCA TCTCCCTTAT TTGCATTGCA GTCTGGATCA TAAACATTGG GCATTTCAAT 
GACCCAGTTC ATGGAGGCTC CTGGATTAGA GGTGCTATTT ACTACTTTAA GATTGCAGTG 
GCCCTGGCGG TAGCAGCTAT TCCTGAAGGT CTGCCTGCCG TCATCACCAC CTGCCTGGCT 
CTTGGAACTC GCAGGATGGC AAAGAAAAAC GCCATCGTCC GAAGCCTGCC TTCTGTGGAA 
ACCCTCGGCT GCACTTCTGT GATCTGCTCT GACAAGACTG GCACACTCAC AACAAACCAG 
ATGTCAGTCT GCAGGATGTT CATCCTGGAC AAGGTTGATG GTGATACTTG TTCCCTGAAT 
GAGTTCACCA TAACTGGATC AACGTACGCA CCTATTGGAG AAGTGCATAA AGATGATAAA 
CCAGTGAAGT GTCATCAGTA TGATGGTCTT GTAGAATTAG CAACAATTTG TGCTCTTTGT 
AATGACTCTG CTTTGGATTA CAATGAGGCC AAAGGTGTGT ATGAAAAGGT TGGAGAAGCT 
ACAGAGACTG CCCTGACGTG CCTGGTGGAG AAGATGAACG TGTTTGACAC TGAATTGAAG 
GGTCTCTCTA AAATAGAGCG CGCGAATGCC TGCAACTCGG TCATTAAGCA GCTGATGAAA 
AAGGAATTCA CTCTAGAATT TTCACGTGAT AGAAAATCAA TGTCAGTGTA TTGTACGCCA 
AACAAACCAA GCCGGACGTC CATGAGCAAG ATGTTTGTGA AGGGTGCTCC TGAGGGTGTC 
ATCGACAGGT GCACCCACAT TCGGGTTGGA AGTACCAAGG TCCCCATGAC AGCTGGAGTC 
AAGCAGAAGA TCATGTCTGT CATTCGGGAA TGGGGTAGTG GCAGCGACAC ACTGCGGTGC 
CTGGCCCTGG CCACTCACGA CAACCCACTG AGAAGAGAAG AAATGCACCT GGAGGACTCT 
GCCAACTTTA TTAAGTATGA GACCAACCTG ACTTTTGTTG GCTGCGTGGG CATGCTGGAT 
CCTCCCAGGA TTGAGGTGGC CTCCTCCGTG AAGCTGTGCC GGCAAGCAGG CATCCGGGTC 
ATCATGATCA CCGGGGACAA CAAGGGTACT GCCGTAGCCA TCTGTCGCCG CATTGGCATC 
TTTGGTCAGG AGGAGGATGT GACGGCCAAG GCTTTCACAG GCCGGGAGTT TGACGAACTC 
AACCCCTCAG CCCAGCGAGA TGCTTGCCTA AATGCCCGCT GCTTTGCTCG AGTTGAACCT 
TCCCACAAGT CCAAGATCGT AGAATTTCTT CAGTCCTTTG ATGAGATCAC AGCTATGACT 
GGCGACGGTG TGAATGATGC CCCTGCTCTG AAGAAAGCGG AGATTGGCAT TGCCATGGGC 
TCTGGCACCG CGGTGGCTAA AACTGCCTCT GAGATGGTCC TGGCTGATGA CAACTTCTCC 
ACCATTGTGG CTGCTGTGGA GGAGGGGCGG GCCATCTACA ACAACATGAA GCAGTTCATC 
CGCTACCTCA TCTCCTCCAA CGTGGGGGAG GTTGTCTGCA TTTTCCTGAC GGCAGCCCTT 
GGGTTTCCTG AGGCCCTGAT TCCCGTGCAG CTGCTCTGGG TCAATCTGGT GACAGATGGC 
CTGCCTGCCA CCGCGCTGGG CTTCAACCCT CCGGATCTGG ACATCATGAA TAAACCGCCT 
CGGAACCCAA AGGAACCACT GATCAGCGGG TGGCTCTTTT TCCGTTACCT GGCTATTGGC 
TGTTACGTTG GCGCCGCGAC AGTGGGTGCT GCTGCGTGGT GGTTCATTGC TGCCGATGGT 
GGTCCAAGAG TGTCCTTCTA CCAGCTGAGT CACTTCCTGC AGTGTAAAGA GGACAACCCG 
GACTTCGAGG GCGTGGATTG TGCAATCTTT GAGTCTCCAT ATCCCATGAC AATGGCACTG 
TCTGTTCTGG TCACCATAGA GATGTGCAAC GCCCTCAACA GCCTGTCTGA AAACCAGTCC 
TTGCTGCGGA TGCCGCCCTG GGAGAACATC TGGCTGGTGG GCTCCATCTG CCTGTCCATG 
TCACTGCACT TCCTCATCCT CTACGTCGAG CCCCTGCCGC TTATCTTCCA GATCACACCG 
CTGAATGTGA CCCAGTGGCT GATGGTGCTG AAAATCTCCT TACCTGTGAT TCTCATGGAC 
GAGACTCTCA AGTTCGTGGC CCGCAACTAC CTGGAACCTG GTAAAGAGTG TGTGCAGCCT 
GCCCCCCAGT CCTGCTCGTT GTGGGCGTGC ACCGAGGGGG TCTCCTGGCC GTTTGTGCTG 
CTCATAGTGC CCCTGGTGAT GTGGGTCTAC AGCACCGACA CTAACTTCAG CGATCTGCTC 
TGGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pulmonary artery banding alters the expression of Ca2+ transport proteins in the right atrium in rabbits.
American journal of physiology. Heart and circulatory physiology296(6)H1933-9(2009 Jun)
Gupta SC,Varian KD,Bal NC,Abraham JL,Periasamy M,Janssen PM

Regulation of fast skeletal muscle activity by SERCA1 vicinal-cysteines.
Journal of muscle research and cell motility30(1-2)5-16(2009)
Alvarez R,Vázquez P,Pérez F,Jiménez A,Tirado A,Irles C,González-Serratos H,Ortega A

Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and sarcoplasmic reticulum Ca2+ ATPase isoform 1 heat production.
Endocrinology149(12)6262-71(2008 Dec)
Arruda AP,Ketzer LA,Nigro M,Galina A,Carvalho DP,de Meis L

How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump.
Proceedings of the National Academy of Sciences of the United States of America104(50)19831-6(2007 Dec)
Toyoshima C,Norimatsu Y,Iwasawa S,Tsuda T,Ogawa H

Amino-acid sequence of a Ca2+ + Mg2+-dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence.
Nature316(6030)696-700(1985 Aug 22-28)
MacLennan DH,Brandl CJ,Korczak B,Green NM

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ATP2A2 cDNA ORF clone, Oryctolagus cuniculus(rabbit)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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