| Gene Symbol | CTSK |
| Entrez Gene ID | 100009334 |
| Full Name | cathepsin K |
| Synonyms | OC-2 |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
IVD Raw Materials
ORF » Species Summary » Oryctolagus cuniculus » CTSK cDNA ORF clone
| Gene Symbol | CTSK |
| Entrez Gene ID | 100009334 |
| Full Name | cathepsin K |
| Synonyms | OC-2 |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
| mRNA | Protein | Name |
|---|---|---|
| NM_001082641.1 | NP_001076110.1 | cathepsin K precursor |
| XM_017345490.1 | XP_017200979.1 | cathepsin K isoform X1 |
Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis.
Kubler A, Larsson C, Luna B, Andrade BB, Amaral EP, Urbanowski M, Orandle M, Bock K, Ammerman NC, Cheung LS, Winglee K, Halushka M, Park JK, Sher A, Friedland JS, Elkington PT, Bishai WR
The Journal of infectious diseases213(4)618-27(2016 Feb)
Down-regulation of cathepsin K in synovium leads to progression of osteoarthritis in rabbits.
Takahashi D, Iwasaki N, Kon S, Matsui Y, Majima T, Minami A, Uede T
Arthritis and rheumatism60(8)2372-80(2009 Aug)
Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts.
Tezuka K, Tezuka Y, Maejima A, Sato T, Nemoto K, Kamioka H, Hakeda Y, Kumegawa M
The Journal of biological chemistry269(2)1106-9(1994 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following CTSK gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CTSK cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OOb00068 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001082641.1 , XM_017345490.1 | |
| Accession Version | NM_001082641.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1577116800000 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | cathepsin K precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D14036.1. ##Evidence-Data-START## Transcript exon combination :: D14036.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1876818, SAMEA1876819 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTGGGGAC TCAAGGTTCT GCTGCTACCC GTGGTGAGTT TTGCTCTGCA CCCTGAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001076110.1 |
| CDS | 25..1014 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001082641.1 |
1 | ATGTGGGGAC TCAAGGTTCT GCTGCTACCC GTGGTGAGTT TTGCTCTGCA CCCTGAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OOb00068 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001082641.1 , XM_017345490.1 | |
| Accession Version | XM_017345490.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1466524800000 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | cathepsin K isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_013681.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Oryctolagus cuniculus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGGGAC TCAAGGTTCT GCTGCTACCC GTGGTGAGTT TTGCTCTGCA CCCTGAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017200979.1 |
| CDS | 287..1276 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017345490.1 |
1 | ATGTGGGGAC TCAAGGTTCT GCTGCTACCC GTGGTGAGTT TTGCTCTGCA CCCTGAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis. |
Down-regulation of cathepsin K in synovium leads to progression of osteoarthritis in rabbits. |
Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts. |