Abcb5 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcb5
Entrez Gene ID	77706
Full Name	ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms	9230106F14Rik
General protein information	Preferred Names ATP-binding cassette, sub-family B (MDR/TAP), member 5 Names ATP-binding cassette sub-family B member 5 ABCB5 P-gp P-glycoprotein ABCB5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 F2

mRNA and Protein(s)

mRNA	Protein	Name
XM_017315245.1	XP_017170734.1	ATP-binding cassette sub-family B member 5 isoform X2
XM_017315245.2	XP_017170734.1	ATP-binding cassette sub-family B member 5 isoform X2
XM_006516370.3	XP_006516433.1	ATP-binding cassette sub-family B member 5 isoform X1
NM_029961.2	NP_084237.1	ATP-binding cassette sub-family B member 5

Pathways from BioSystems

Homologies

Magnaporthe oryzae (rice blast fungus)	MGG_15334	XP_003714927.1
Magnaporthe oryzae (rice blast fungus)	MGG_14400	XP_003713269.1
Pan troglodytes (chimpanzee)	ABCB5	XP_001152831.2
Macaca mulatta (Rhesus monkey)	LOC712883	XP_001102010.2
Bos taurus (cattle)	LOC536724	XP_002686751.1
Mus musculus (house mouse)	Abcb5	NP_084237.1
Rattus norvegicus (Norway rat)	Abcb5	XP_006240775.1
Xenopus tropicalis (tropical clawed frog)	LOC100485969	XP_002932444.2
Xenopus tropicalis (tropical clawed frog)	LOC100492825	XP_002933334.1
Arabidopsis thaliana (thale cress)	PGP13	NP_174115.1
Xenopus tropicalis (tropical clawed frog)	abcb5	NP_989254.1
Canis lupus familiaris (dog)	ABCB5	XP_005628664.1
Arabidopsis thaliana (thale cress)	PGP14	NP_174122.1
Homo sapiens (human)	ABCB5	NP_001157413.1

Gene Ontology
Bibliography

Related articles in PubMed

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.
King R, Struebing FL, Li Y, Wang J, Koch AA, Cooke Bailey JN, Gharahkhani P, , , MacGregor S, Allingham RR, Hauser MA, Wiggs JL, Geisert EE
PLoS genetics14(1)e1007145(2018 01)

Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells.
Kondo S, Hongama K, Hanaya K, Yoshida R, Kawanobe T, Katayama K, Noguchi K, Sugimoto Y
BMC pharmacology & toxicology1637(2015 Dec)

The role of Abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans.
Zheng M, Zhang H, Dill DL, Clark JD, Tu S, Yablonovitch AL, Tan MH, Zhang R, Rujescu D, Wu M, Tessarollo L, Vieira W, Gottesman MM, Deng S, Eberlin LS, Zare RN, Billard JM, Gillet JP, Li JB, Peltz G
PLoS medicine12(2)e1001782(2015 Feb)

ABCB5 is a limbal stem cell gene required for corneal development and repair.
Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY
Nature511(7509)353-7(2014 Jul)

The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo.
Linley AJ, Mathieu MG, Miles AK, Rees RC, McArdle SE, Regad T
The Journal of biological chemistry287(17)13633-43(2012 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Abcb5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcb5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu78342	XM_017315245.2 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu07746	NM_029961.2 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OMu48194	XM_006516370.3 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
View Old Accession Versions >>
OMu78342	XM_017315245.1	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcb5 ( XM_017315245.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170734.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu78342
Clone ID Related Accession (Same CDS sequence)	XM_017315245.1 , XM_017315245.2
Accession Version	XM_017315245.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2832bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAAATT CTGAAAGAAC CAACGGGTTG CAAGAAACTA ATCAGAGATA TGGACCTCTG 
CAAGAACAAG TGCCTAAAGT GGGAAATCAA GCTGTTGGAC CTATTGAGAT ATTCCGCTTT 
GCTGATAATC TGGACATTGT CCTCATGACT CTGGGAATAT TAGCATCCAT GATAAATGGA 
GCCACCGTTC CTTTAATGTC CCTGGTTTTA GGAGAAATAA GTGATCATTT AATTAATGGA 
TGCCTAGTAC AAACTAACAG AACTAAATAT CAGAACTGTT CTCAGACTCA AGAAAAGCTG 
AATGAAGATA TCATTGTGTT GACTCTATAT TATATTGGAA TAGGAGCAGC TGCCCTCATT 
TTTGGCTATG TACAGATTTC CTTCTGGGTC ATAACTGCAG CCCGGCAAAC CACAAGAATC 
CGAAAACAGT TTTTTCATTC AATTTTGGCA CAAGACATCA GCTGGTTTGA TGGCAGTGAC 
ATCTGTGAAC TTAACACCCG CATGACTGGT GACATCAACA AACTCTGTGA TGGTATTGGA 
GATAAGATCC CTCTGATGTT TCAGAACATA TCTGGGTTTT CTATTGGCCT GGTGATAAGT 
TTGATAAAAA GCTGGAAACT CTCCCTGGTG GTTCTGTCTA CATCTCCTCT CATAATGGCT 
TCATCGGCAC TGTGCTCTAG GATGATTATC TCATTGACCA GCAAGGAGCT GGATGCCTAT 
TCCAAAGCTG GGGCTGTGGC TGAAGAAGCC TTGTCATCAA TCCAAACAGT CACAGCCTTT 
GGAGCCCAAG AGAAAGAAAT TCAAAGGTAT ACACAGCACT TAAAGGACGC AAAGGACGCT 
GGCATAAAGA GGGCTACGGC TTCAAAGCTG TCTCTTGGAG CAGTCTACTT CTTTATGAAT 
GGAGCCTATG GACTGGCTTT TTGGTATGGA ACCTCCTTGA TTTTTGGCGG AGAGCCTGGT 
TACACCATCG GAACTATTCT TGCTGTTTTC TTCAGTGTGA TCCATAGTAG TTACTGCATT 
GGATCTGTAG CCCCTCACCT GGAAACCTTC ACAGTAGCCA GAGGAGCTGC CTTTAATATT 
TTCCAGGTTA TTGATAAGAA ACCCAATATA GATAACTTTT CAACAGCTGG ATTTGTACCT 
GAATGTATAG AAGGAAACAT AGAATTTAAA AATGTTTCTT TCAGCTATCC ATCAAGACCT 
TCTGCCAAGG TTCTGAAAGG TCTCAATCTG AAGATTAAGG CTGGAGAGAC AGTAGCCTTG 
GTTGGTCCCA GTGGCAGTGG CAAGAGTACG ACAGTGCAGC TTCTGCAGAG GCTGTATGAC 
CCAGAGGACG GCTGTATCAC CGTAGATGAG AATGACATCC GAGCCCAAAA CGTGCGACAT 
TACCGAGAGC AAATTGGAGT GGTCAGACAA GAGCCAGTTC TGTTTGGGAC CACCATCGGT 
AACAATATTA AGTTTGGGCG CGAAGGTGTG GGTGAAAAGG AAATGGAACA GGCAGCGAGG 
GAGGCAAACG CCTACGACTT CATAATGGCC TTTCCTAAGA AATTTAATAC ACTAGTAGGG 
GAAAAAGGAG CTCAAATGAG TGGAGGCCAG AAACAGAGGA TTGCCATTGC TCGAGCGCTA 
GTTCGAAACC CCAAAATTCT GATCTTAGAT GAGGCTACAT CTGCCCTGGA CACAGAGAGT 
GAATCACTTG TTCAAACTGC ACTGGAGAAG GCAAGCAAAG GCCGGACTAC AATTGTGGTA 
GCACACAGGC TCTCCACCAT TCGTGGGGCA GACCTGATTG TGACAATGAA GGATGGCATG 
GTGGTGGAGA AAGGGACCCA TGCTGAACTA ATGGCAAAGC AGGGGCTGTA CTACTCCCTC 
GCCATGGCAC AGGATATTAA AAAGGTCGAT GAACAAATGG AATCAAGGAC ATGTTCCACT 
GCAGGAAATG CCAGCTATGG TTCTCTGTGC GATGTGAATA GTGCCAAGGC CCCCTGCACT 
GACCAGCTGG AGGAAGCCGT ACACCATCAA AAGACAAGTC TTCCTGAAGT TTCACTATTA 
AAAATATTTA AATTAAGCAA GTCTGAATGG CCTTTTGTGG TTCTGGGAAC ACTGGCTTCT 
GCTTTAAATG GATCTGTTCA TCCAGTATTT TCCATCATCT TTGGAAAATT AGTCACTATG 
TTTGAAGATA AAAATAAAGC TACATTAAAG CAGGATGCAG AGCTCTACTC CATGATGTTA 
GTCGTCTTGG GCATAGTAGC TCTTGTCACC TACTTGATGC AGGGATTGTT TTATGGCAGA 
GCAGAGGAAA ATTTAGCCAT GAGATTAAGA CACTCGGCAT TCAAAGCCAT GCTCTACCAG 
GATATGGCCT GGTATGATGA TAAAGAGAAC AACACTGGAG CCCTGACCAC AACGTTAGCT 
GTGGATGTAG CACAGATTCA GGGTGCAGCA ACTTCAAGAC TTGGGATCGT AACACAAGAT 
GTGAGCAACA TGAGTCTGTC CATTCTCATC TCCTTCATAT ATGGATGGGA GATGACACTC 
CTGATTCTCA GCTTCGCGCC TGTACTTGCG GTGACAGGAA TGATTCAAAC CGCAGCAATG 
GCTGGCTTTG CCAACAGGGA TAAGCAGGCG CTCAAGCGTG CTGGAAAGAA ACGCCTTGAA 
GAGAGCACAC ATCACTGGAT GCTGTTATGC AGTCAGCCAT GCTTTTGTGC ATTTTGCCCA 
TGCAGCAGGG TTCCGATTTG GAGCCTATTT GATTCAAGCA GGACGGATGA TGCCGGAAGG 
CATGTTCATA GTCTTTACCG CCATTGCATA TGGGGCTATG GCCATTGGAG AAACACTTGT 
ATGGGCTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170734.1
CDS	211..3042
Translation	MANSERTNGLQETNQRYGPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLINGCLVQTNRTKYQNCSQTQEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAKQGLYYSLAMAQDIKKVDEQMESRTCSTAGNASYGSLCDVNSAKAPCTDQLEEAVHHQKTSLPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVTMFEDKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKKRLEESTHHWMLLCSQPCFCAFCPCSRVPIWSLFDSSRTDDAGRHVHSLYRHCIWGYGHWRNTCMGS

Target ORF information:

RefSeq Version	XM_017315245.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017315245.1

ORF Insert Sequence:

ATGGCAAATT CTGAAAGAAC CAACGGGTTG CAAGAAACTA ATCAGAGATA TGGACCTCTG 
CAAGAACAAG TGCCTAAAGT GGGAAATCAA GCTGTTGGAC CTATTGAGAT ATTCCGCTTT 
GCTGATAATC TGGACATTGT CCTCATGACT CTGGGAATAT TAGCATCCAT GATAAATGGA 
GCCACCGTTC CTTTAATGTC CCTGGTTTTA GGAGAAATAA GTGATCATTT AATTAATGGA 
TGCCTAGTAC AAACTAACAG AACTAAATAT CAGAACTGTT CTCAGACTCA AGAAAAGCTG 
AATGAAGATA TCATTGTGTT GACTCTATAT TATATTGGAA TAGGAGCAGC TGCCCTCATT 
TTTGGCTATG TACAGATTTC CTTCTGGGTC ATAACTGCAG CCCGGCAAAC CACAAGAATC 
CGAAAACAGT TTTTTCATTC AATTTTGGCA CAAGACATCA GCTGGTTTGA TGGCAGTGAC 
ATCTGTGAAC TTAACACCCG CATGACTGGT GACATCAACA AACTCTGTGA TGGTATTGGA 
GATAAGATCC CTCTGATGTT TCAGAACATA TCTGGGTTTT CTATTGGCCT GGTGATAAGT 
TTGATAAAAA GCTGGAAACT CTCCCTGGTG GTTCTGTCTA CATCTCCTCT CATAATGGCT 
TCATCGGCAC TGTGCTCTAG GATGATTATC TCATTGACCA GCAAGGAGCT GGATGCCTAT 
TCCAAAGCTG GGGCTGTGGC TGAAGAAGCC TTGTCATCAA TCCAAACAGT CACAGCCTTT 
GGAGCCCAAG AGAAAGAAAT TCAAAGGTAT ACACAGCACT TAAAGGACGC AAAGGACGCT 
GGCATAAAGA GGGCTACGGC TTCAAAGCTG TCTCTTGGAG CAGTCTACTT CTTTATGAAT 
GGAGCCTATG GACTGGCTTT TTGGTATGGA ACCTCCTTGA TTTTTGGCGG AGAGCCTGGT 
TACACCATCG GAACTATTCT TGCTGTTTTC TTCAGTGTGA TCCATAGTAG TTACTGCATT 
GGATCTGTAG CCCCTCACCT GGAAACCTTC ACAGTAGCCA GAGGAGCTGC CTTTAATATT 
TTCCAGGTTA TTGATAAGAA ACCCAATATA GATAACTTTT CAACAGCTGG ATTTGTACCT 
GAATGTATAG AAGGAAACAT AGAATTTAAA AATGTTTCTT TCAGCTATCC ATCAAGACCT 
TCTGCCAAGG TTCTGAAAGG TCTCAATCTG AAGATTAAGG CTGGAGAGAC AGTAGCCTTG 
GTTGGTCCCA GTGGCAGTGG CAAGAGTACG ACAGTGCAGC TTCTGCAGAG GCTGTATGAC 
CCAGAGGACG GCTGTATCAC CGTAGATGAG AATGACATCC GAGCCCAAAA CGTGCGACAT 
TACCGAGAGC AAATTGGAGT GGTCAGACAA GAGCCAGTTC TGTTTGGGAC CACCATCGGT 
AACAATATTA AGTTTGGGCG CGAAGGTGTG GGTGAAAAGG AAATGGAACA GGCAGCGAGG 
GAGGCAAACG CCTACGACTT CATAATGGCC TTTCCTAAGA AATTTAATAC ACTAGTAGGG 
GAAAAAGGAG CTCAAATGAG TGGAGGCCAG AAACAGAGGA TTGCCATTGC TCGAGCGCTA 
GTTCGAAACC CCAAAATTCT GATCTTAGAT GAGGCTACAT CTGCCCTGGA CACAGAGAGT 
GAATCACTTG TTCAAACTGC ACTGGAGAAG GCAAGCAAAG GCCGGACTAC AATTGTGGTA 
GCACACAGGC TCTCCACCAT TCGTGGGGCA GACCTGATTG TGACAATGAA GGATGGCATG 
GTGGTGGAGA AAGGGACCCA TGCTGAACTA ATGGCAAAGC AGGGGCTGTA CTACTCCCTC 
GCCATGGCAC AGGATATTAA AAAGGTCGAT GAACAAATGG AATCAAGGAC ATGTTCCACT 
GCAGGAAATG CCAGCTATGG TTCTCTGTGC GATGTGAATA GTGCCAAGGC CCCCTGCACT 
GACCAGCTGG AGGAAGCCGT ACACCATCAA AAGACAAGTC TTCCTGAAGT TTCACTATTA 
AAAATATTTA AATTAAGCAA GTCTGAATGG CCTTTTGTGG TTCTGGGAAC ACTGGCTTCT 
GCTTTAAATG GATCTGTTCA TCCAGTATTT TCCATCATCT TTGGAAAATT AGTCACTATG 
TTTGAAGATA AAAATAAAGC TACATTAAAG CAGGATGCAG AGCTCTACTC CATGATGTTA 
GTCGTCTTGG GCATAGTAGC TCTTGTCACC TACTTGATGC AGGGATTGTT TTATGGCAGA 
GCAGAGGAAA ATTTAGCCAT GAGATTAAGA CACTCGGCAT TCAAAGCCAT GCTCTACCAG 
GATATGGCCT GGTATGATGA TAAAGAGAAC AACACTGGAG CCCTGACCAC AACGTTAGCT 
GTGGATGTAG CACAGATTCA GGGTGCAGCA ACTTCAAGAC TTGGGATCGT AACACAAGAT 
GTGAGCAACA TGAGTCTGTC CATTCTCATC TCCTTCATAT ATGGATGGGA GATGACACTC 
CTGATTCTCA GCTTCGCGCC TGTACTTGCG GTGACAGGAA TGATTCAAAC CGCAGCAATG 
GCTGGCTTTG CCAACAGGGA TAAGCAGGCG CTCAAGCGTG CTGGAAAGAA ACGCCTTGAA 
GAGAGCACAC ATCACTGGAT GCTGTTATGC AGTCAGCCAT GCTTTTGTGC ATTTTGCCCA 
TGCAGCAGGG TTCCGATTTG GAGCCTATTT GATTCAAGCA GGACGGATGA TGCCGGAAGG 
CATGTTCATA GTCTTTACCG CCATTGCATA TGGGGCTATG GCCATTGGAG AAACACTTGT 
ATGGGCTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb5 ( XM_017315245.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170734.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu78342
Clone ID Related Accession (Same CDS sequence)	XM_017315245.1 , XM_017315245.2
Accession Version	XM_017315245.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2832bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017315245.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAAATT CTGAAAGAAC CAACGGGTTG CAAGAAACTA ATCAGAGATA TGGACCTCTG 
CAAGAACAAG TGCCTAAAGT GGGAAATCAA GCTGTTGGAC CTATTGAGAT ATTCCGCTTT 
GCTGATAATC TGGACATTGT CCTCATGACT CTGGGAATAT TAGCATCCAT GATAAATGGA 
GCCACCGTTC CTTTAATGTC CCTGGTTTTA GGAGAAATAA GTGATCATTT AATTAATGGA 
TGCCTAGTAC AAACTAACAG AACTAAATAT CAGAACTGTT CTCAGACTCA AGAAAAGCTG 
AATGAAGATA TCATTGTGTT GACTCTATAT TATATTGGAA TAGGAGCAGC TGCCCTCATT 
TTTGGCTATG TACAGATTTC CTTCTGGGTC ATAACTGCAG CCCGGCAAAC CACAAGAATC 
CGAAAACAGT TTTTTCATTC AATTTTGGCA CAAGACATCA GCTGGTTTGA TGGCAGTGAC 
ATCTGTGAAC TTAACACCCG CATGACTGGT GACATCAACA AACTCTGTGA TGGTATTGGA 
GATAAGATCC CTCTGATGTT TCAGAACATA TCTGGGTTTT CTATTGGCCT GGTGATAAGT 
TTGATAAAAA GCTGGAAACT CTCCCTGGTG GTTCTGTCTA CATCTCCTCT CATAATGGCT 
TCATCGGCAC TGTGCTCTAG GATGATTATC TCATTGACCA GCAAGGAGCT GGATGCCTAT 
TCCAAAGCTG GGGCTGTGGC TGAAGAAGCC TTGTCATCAA TCCAAACAGT CACAGCCTTT 
GGAGCCCAAG AGAAAGAAAT TCAAAGGTAT ACACAGCACT TAAAGGACGC AAAGGACGCT 
GGCATAAAGA GGGCTACGGC TTCAAAGCTG TCTCTTGGAG CAGTCTACTT CTTTATGAAT 
GGAGCCTATG GACTGGCTTT TTGGTATGGA ACCTCCTTGA TTTTTGGCGG AGAGCCTGGT 
TACACCATCG GAACTATTCT TGCTGTTTTC TTCAGTGTGA TCCATAGTAG TTACTGCATT 
GGATCTGTAG CCCCTCACCT GGAAACCTTC ACAGTAGCCA GAGGAGCTGC CTTTAATATT 
TTCCAGGTTA TTGATAAGAA ACCCAATATA GATAACTTTT CAACAGCTGG ATTTGTACCT 
GAATGTATAG AAGGAAACAT AGAATTTAAA AATGTTTCTT TCAGCTATCC ATCAAGACCT 
TCTGCCAAGG TTCTGAAAGG TCTCAATCTG AAGATTAAGG CTGGAGAGAC AGTAGCCTTG 
GTTGGTCCCA GTGGCAGTGG CAAGAGTACG ACAGTGCAGC TTCTGCAGAG GCTGTATGAC 
CCAGAGGACG GCTGTATCAC CGTAGATGAG AATGACATCC GAGCCCAAAA CGTGCGACAT 
TACCGAGAGC AAATTGGAGT GGTCAGACAA GAGCCAGTTC TGTTTGGGAC CACCATCGGT 
AACAATATTA AGTTTGGGCG CGAAGGTGTG GGTGAAAAGG AAATGGAACA GGCAGCGAGG 
GAGGCAAACG CCTACGACTT CATAATGGCC TTTCCTAAGA AATTTAATAC ACTAGTAGGG 
GAAAAAGGAG CTCAAATGAG TGGAGGCCAG AAACAGAGGA TTGCCATTGC TCGAGCGCTA 
GTTCGAAACC CCAAAATTCT GATCTTAGAT GAGGCTACAT CTGCCCTGGA CACAGAGAGT 
GAATCACTTG TTCAAACTGC ACTGGAGAAG GCAAGCAAAG GCCGGACTAC AATTGTGGTA 
GCACACAGGC TCTCCACCAT TCGTGGGGCA GACCTGATTG TGACAATGAA GGATGGCATG 
GTGGTGGAGA AAGGGACCCA TGCTGAACTA ATGGCAAAGC AGGGGCTGTA CTACTCCCTC 
GCCATGGCAC AGGATATTAA AAAGGTCGAT GAACAAATGG AATCAAGGAC ATGTTCCACT 
GCAGGAAATG CCAGCTATGG TTCTCTGTGC GATGTGAATA GTGCCAAGGC CCCCTGCACT 
GACCAGCTGG AGGAAGCCGT ACACCATCAA AAGACAAGTC TTCCTGAAGT TTCACTATTA 
AAAATATTTA AATTAAGCAA GTCTGAATGG CCTTTTGTGG TTCTGGGAAC ACTGGCTTCT 
GCTTTAAATG GATCTGTTCA TCCAGTATTT TCCATCATCT TTGGAAAATT AGTCACTATG 
TTTGAAGATA AAAATAAAGC TACATTAAAG CAGGATGCAG AGCTCTACTC CATGATGTTA 
GTCGTCTTGG GCATAGTAGC TCTTGTCACC TACTTGATGC AGGGATTGTT TTATGGCAGA 
GCAGAGGAAA ATTTAGCCAT GAGATTAAGA CACTCGGCAT TCAAAGCCAT GCTCTACCAG 
GATATGGCCT GGTATGATGA TAAAGAGAAC AACACTGGAG CCCTGACCAC AACGTTAGCT 
GTGGATGTAG CACAGATTCA GGGTGCAGCA ACTTCAAGAC TTGGGATCGT AACACAAGAT 
GTGAGCAACA TGAGTCTGTC CATTCTCATC TCCTTCATAT ATGGATGGGA GATGACACTC 
CTGATTCTCA GCTTCGCGCC TGTACTTGCG GTGACAGGAA TGATTCAAAC CGCAGCAATG 
GCTGGCTTTG CCAACAGGGA TAAGCAGGCG CTCAAGCGTG CTGGAAAGAA ACGCCTTGAA 
GAGAGCACAC ATCACTGGAT GCTGTTATGC AGTCAGCCAT GCTTTTGTGC ATTTTGCCCA 
TGCAGCAGGG TTCCGATTTG GAGCCTATTT GATTCAAGCA GGACGGATGA TGCCGGAAGG 
CATGTTCATA GTCTTTACCG CCATTGCATA TGGGGCTATG GCCATTGGAG AAACACTTGT 
ATGGGCTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170734.1
CDS	98..2929
Translation	MANSERTNGLQETNQRYGPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLINGCLVQTNRTKYQNCSQTQEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAKQGLYYSLAMAQDIKKVDEQMESRTCSTAGNASYGSLCDVNSAKAPCTDQLEEAVHHQKTSLPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVTMFEDKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKKRLEESTHHWMLLCSQPCFCAFCPCSRVPIWSLFDSSRTDDAGRHVHSLYRHCIWGYGHWRNTCMGS

Target ORF information:

RefSeq Version	XM_017315245.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017315245.2

ORF Insert Sequence:

ATGGCAAATT CTGAAAGAAC CAACGGGTTG CAAGAAACTA ATCAGAGATA TGGACCTCTG 
CAAGAACAAG TGCCTAAAGT GGGAAATCAA GCTGTTGGAC CTATTGAGAT ATTCCGCTTT 
GCTGATAATC TGGACATTGT CCTCATGACT CTGGGAATAT TAGCATCCAT GATAAATGGA 
GCCACCGTTC CTTTAATGTC CCTGGTTTTA GGAGAAATAA GTGATCATTT AATTAATGGA 
TGCCTAGTAC AAACTAACAG AACTAAATAT CAGAACTGTT CTCAGACTCA AGAAAAGCTG 
AATGAAGATA TCATTGTGTT GACTCTATAT TATATTGGAA TAGGAGCAGC TGCCCTCATT 
TTTGGCTATG TACAGATTTC CTTCTGGGTC ATAACTGCAG CCCGGCAAAC CACAAGAATC 
CGAAAACAGT TTTTTCATTC AATTTTGGCA CAAGACATCA GCTGGTTTGA TGGCAGTGAC 
ATCTGTGAAC TTAACACCCG CATGACTGGT GACATCAACA AACTCTGTGA TGGTATTGGA 
GATAAGATCC CTCTGATGTT TCAGAACATA TCTGGGTTTT CTATTGGCCT GGTGATAAGT 
TTGATAAAAA GCTGGAAACT CTCCCTGGTG GTTCTGTCTA CATCTCCTCT CATAATGGCT 
TCATCGGCAC TGTGCTCTAG GATGATTATC TCATTGACCA GCAAGGAGCT GGATGCCTAT 
TCCAAAGCTG GGGCTGTGGC TGAAGAAGCC TTGTCATCAA TCCAAACAGT CACAGCCTTT 
GGAGCCCAAG AGAAAGAAAT TCAAAGGTAT ACACAGCACT TAAAGGACGC AAAGGACGCT 
GGCATAAAGA GGGCTACGGC TTCAAAGCTG TCTCTTGGAG CAGTCTACTT CTTTATGAAT 
GGAGCCTATG GACTGGCTTT TTGGTATGGA ACCTCCTTGA TTTTTGGCGG AGAGCCTGGT 
TACACCATCG GAACTATTCT TGCTGTTTTC TTCAGTGTGA TCCATAGTAG TTACTGCATT 
GGATCTGTAG CCCCTCACCT GGAAACCTTC ACAGTAGCCA GAGGAGCTGC CTTTAATATT 
TTCCAGGTTA TTGATAAGAA ACCCAATATA GATAACTTTT CAACAGCTGG ATTTGTACCT 
GAATGTATAG AAGGAAACAT AGAATTTAAA AATGTTTCTT TCAGCTATCC ATCAAGACCT 
TCTGCCAAGG TTCTGAAAGG TCTCAATCTG AAGATTAAGG CTGGAGAGAC AGTAGCCTTG 
GTTGGTCCCA GTGGCAGTGG CAAGAGTACG ACAGTGCAGC TTCTGCAGAG GCTGTATGAC 
CCAGAGGACG GCTGTATCAC CGTAGATGAG AATGACATCC GAGCCCAAAA CGTGCGACAT 
TACCGAGAGC AAATTGGAGT GGTCAGACAA GAGCCAGTTC TGTTTGGGAC CACCATCGGT 
AACAATATTA AGTTTGGGCG CGAAGGTGTG GGTGAAAAGG AAATGGAACA GGCAGCGAGG 
GAGGCAAACG CCTACGACTT CATAATGGCC TTTCCTAAGA AATTTAATAC ACTAGTAGGG 
GAAAAAGGAG CTCAAATGAG TGGAGGCCAG AAACAGAGGA TTGCCATTGC TCGAGCGCTA 
GTTCGAAACC CCAAAATTCT GATCTTAGAT GAGGCTACAT CTGCCCTGGA CACAGAGAGT 
GAATCACTTG TTCAAACTGC ACTGGAGAAG GCAAGCAAAG GCCGGACTAC AATTGTGGTA 
GCACACAGGC TCTCCACCAT TCGTGGGGCA GACCTGATTG TGACAATGAA GGATGGCATG 
GTGGTGGAGA AAGGGACCCA TGCTGAACTA ATGGCAAAGC AGGGGCTGTA CTACTCCCTC 
GCCATGGCAC AGGATATTAA AAAGGTCGAT GAACAAATGG AATCAAGGAC ATGTTCCACT 
GCAGGAAATG CCAGCTATGG TTCTCTGTGC GATGTGAATA GTGCCAAGGC CCCCTGCACT 
GACCAGCTGG AGGAAGCCGT ACACCATCAA AAGACAAGTC TTCCTGAAGT TTCACTATTA 
AAAATATTTA AATTAAGCAA GTCTGAATGG CCTTTTGTGG TTCTGGGAAC ACTGGCTTCT 
GCTTTAAATG GATCTGTTCA TCCAGTATTT TCCATCATCT TTGGAAAATT AGTCACTATG 
TTTGAAGATA AAAATAAAGC TACATTAAAG CAGGATGCAG AGCTCTACTC CATGATGTTA 
GTCGTCTTGG GCATAGTAGC TCTTGTCACC TACTTGATGC AGGGATTGTT TTATGGCAGA 
GCAGAGGAAA ATTTAGCCAT GAGATTAAGA CACTCGGCAT TCAAAGCCAT GCTCTACCAG 
GATATGGCCT GGTATGATGA TAAAGAGAAC AACACTGGAG CCCTGACCAC AACGTTAGCT 
GTGGATGTAG CACAGATTCA GGGTGCAGCA ACTTCAAGAC TTGGGATCGT AACACAAGAT 
GTGAGCAACA TGAGTCTGTC CATTCTCATC TCCTTCATAT ATGGATGGGA GATGACACTC 
CTGATTCTCA GCTTCGCGCC TGTACTTGCG GTGACAGGAA TGATTCAAAC CGCAGCAATG 
GCTGGCTTTG CCAACAGGGA TAAGCAGGCG CTCAAGCGTG CTGGAAAGAA ACGCCTTGAA 
GAGAGCACAC ATCACTGGAT GCTGTTATGC AGTCAGCCAT GCTTTTGTGC ATTTTGCCCA 
TGCAGCAGGG TTCCGATTTG GAGCCTATTT GATTCAAGCA GGACGGATGA TGCCGGAAGG 
CATGTTCATA GTCTTTACCG CCATTGCATA TGGGGCTATG GCCATTGGAG AAACACTTGT 
ATGGGCTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb5 ( NM_029961.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084237.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), mRNA.

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CloneID	OMu07746
Clone ID Related Accession (Same CDS sequence)	NM_029961.2
Accession Version	NM_029961.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK020318.1, AC126277.3, AK139832.1 and AC131717.3. On Aug 11, 2009 this sequence version replaced NM_029961.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY766239.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGCAAATT CTGAAAGAAC CAACGGGTTG CAAGAAACTA ATCAGAGATA TGGACCTCTG 
CAAGAACAAG TGCCTAAAGT GGGAAATCAA GCTGTTGGAC CTATTGAGAT ATTCCGCTTT 
GCTGATAATC TGGACATTGT CCTCATGACT CTGGGAATAT TAGCATCCAT GATAAATGGA 
GCCACCGTTC CTTTAATGTC CCTGGTTTTA GGAGAAATAA GTGATCATTT AATTAATGGA 
TGCCTAGTAC AAACTAACAG AACTAAATAT CAGAACTGTT CTCAGACTCA AGAAAAGCTG 
AATGAAGATA TCATTGTGTT GACTCTATAT TATATTGGAA TAGGAGCAGC TGCCCTCATT 
TTTGGCTATG TACAGATTTC CTTCTGGGTC ATAACTGCAG CCCGGCAAAC CACAAGAATC 
CGAAAACAGT TTTTTCATTC AATTTTGGCA CAAGACATCA GCTGGTTTGA TGGCAGTGAC 
ATCTGTGAAC TTAACACCCG CATGACTGGT GACATCAACA AACTCTGTGA TGGTATTGGA 
GATAAGATCC CTCTGATGTT TCAGAACATA TCTGGGTTTT CTATTGGCCT GGTGATAAGT 
TTGATAAAAA GCTGGAAACT CTCCCTGGTG GTTCTGTCTA CATCTCCTCT CATAATGGCT 
TCATCGGCAC TGTGCTCTAG GATGATTATC TCATTGACCA GCAAGGAGCT GGATGCCTAT 
TCCAAAGCTG GGGCTGTGGC TGAAGAAGCC TTGTCATCAA TCCAAACAGT CACAGCCTTT 
GGAGCCCAAG AGAAAGAAAT TCAAAGGTAT ACACAGCACT TAAAGGACGC AAAGGACGCT 
GGCATAAAGA GGGCTACGGC TTCAAAGCTG TCTCTTGGAG CAGTCTACTT CTTTATGAAT 
GGAGCCTATG GACTGGCTTT TTGGTATGGA ACCTCCTTGA TTTTTGGCGG AGAGCCTGGT 
TACACCATCG GAACTATTCT TGCTGTTTTC TTCAGTGTGA TCCATAGTAG TTACTGCATT 
GGATCTGTAG CCCCTCACCT GGAAACCTTC ACAGTAGCCA GAGGAGCTGC CTTTAATATT 
TTCCAGGTTA TTGATAAGAA ACCCAATATA GATAACTTTT CAACAGCTGG ATTTGTACCT 
GAATGTATAG AAGGAAACAT AGAATTTAAA AATGTTTCTT TCAGCTATCC ATCAAGACCT 
TCTGCCAAGG TTCTGAAAGG TCTCAATCTG AAGATTAAGG CTGGAGAGAC AGTAGCCTTG 
GTTGGTCCCA GTGGCAGTGG CAAGAGTACG ACAGTGCAGC TTCTGCAGAG GCTGTATGAC 
CCAGAGGACG GCTGTATCAC CGTAGATGAG AATGACATCC GAGCCCAAAA CGTGCGACAT 
TACCGAGAGC AAATTGGAGT GGTCAGACAA GAGCCAGTTC TGTTTGGGAC CACCATCGGT 
AACAATATTA AGTTTGGGCG CGAAGGTGTG GGTGAAAAGG AAATGGAACA GGCAGCGAGG 
GAGGCAAACG CCTACGACTT CATAATGGCC TTTCCTAAGA AATTTAATAC ACTAGTAGGG 
GAAAAAGGAG CTCAAATGAG TGGAGGCCAG AAACAGAGGA TTGCCATTGC TCGAGCGCTA 
GTTCGAAACC CCAAAATTCT GATCTTAGAT GAGGCTACAT CTGCCCTGGA CACAGAGAGT 
GAATCACTTG TTCAAACTGC ACTGGAGAAG GCAAGCAAAG GCCGGACTAC AATTGTGGTA 
GCACACAGGC TCTCCACCAT TCGTGGGGCA GACCTGATTG TGACAATGAA GGATGGCATG 
GTGGTGGAGA AAGGGACCCA TGCTGAACTA ATGGCAAAGC AGGGGCTGTA CTACTCCCTC 
GCCATGGCAC AGGATATTAA AAAGGTCGAT GAACAAATGG AATCAAGGAC ATGTTCCACT 
GCAGGAAATG CCAGCTATGG TTCTCTGTGC GATGTGAATA GTGCCAAGGC CCCCTGCACT 
GACCAGCTGG AGGAAGCCGT ACACCATCAA AAGACAAGTC TTCCTGAAGT TTCACTATTA 
AAAATATTTA AATTAAGCAA GTCTGAATGG CCTTTTGTGG TTCTGGGAAC ACTGGCTTCT 
GCTTTAAATG GATCTGTTCA TCCAGTATTT TCCATCATCT TTGGAAAATT AGTCACTATG 
TTTGAAGATA AAAATAAAGC TACATTAAAG CAGGATGCAG AGCTCTACTC CATGATGTTA 
GTCGTCTTGG GCATAGTAGC TCTTGTCACC TACTTGATGC AGGGATTGTT TTATGGCAGA 
GCAGAGGAAA ATTTAGCCAT GAGATTAAGA CACTCGGCAT TCAAAGCCAT GCTCTACCAG 
GATATGGCCT GGTATGATGA TAAAGAGAAC AACACTGGAG CCCTGACCAC AACGTTAGCT 
GTGGATGTAG CACAGATTCA GGGTGCAGCA ACTTCAAGAC TTGGGATCGT AACACAAGAT 
GTGAGCAACA TGAGTCTGTC CATTCTCATC TCCTTCATAT ATGGATGGGA GATGACACTC 
CTGATTCTCA GCTTCGCGCC TGTACTTGCG GTGACAGGAA TGATTCAAAC CGCAGCAATG 
GCTGGCTTTG CCAACAGGGA TAAGCAGGCG CTCAAGCGTG CTGGAAAGAT AGCAACAGAA 
GCTGTGGAGA ACATACGTAC GGTAGTGTCA TTAACAAGAG AGAGAGCCTT TGAGCAAATG 
TATGAGGAGA CACTTCAGAC TCAACACAGA AACGCCTTGA AGAGAGCACA CATCACTGGA 
TGCTGTTATG CAGTCAGCCA TGCTTTTGTG CATTTTGCCC ATGCAGCAGG GTTCCGATTT 
GGAGCCTATT TGATTCAAGC AGGACGGATG ATGCCGGAAG GCATGTTCAT AGTCTTTACC 
GCCATTGCAT ATGGGGCTAT GGCCATTGGA GAAACACTTG TATGGGCTCC TGAATATTCC 
AAAGCCAAAG CTGGAGCTTC GCATCTGTTT GCTTTGCTGA AAAATAAACC AACTATAAAC 
AGCTGCAGTC AAAGTGGGGA AAAACCAGAC ACCTGTGAAG GGAACTTAGA ATTTCGAGAG 
GTCTCTTTCG TCTATCCTTG TCGTCCAGAA GTTCCTGTCC TTCAGAACAT GTCCCTCAGC 
ATTGAGAAAG GGAAGACTGT AGCATTCGTT GGGAGCAGCG GCTGTGGAAA AAGCACATGT 
GTTCAACTGC TGCAAAGATT TTATGACCCC ATGAAAGGAC AAGTGCTGCT TGACGGAGTT 
GATGTAAAAG AATTGAACGT GCAGTGGCTG CGTTCCCAGA CAGCCATCGT CTCCCAAGAG 
CCTGTGCTGT TCAACTGTAG CATCGCTGAG AACATTGCCT ATGGTGATAA CAGCCGCATG 
GTGCCCTTAG AGGAGATCAA AGAGGTCGCA GATGCAGCCA ACATTCATTC TTTCATTGAA 
GGGCTCCCAA GGAAATACAA CACCCTAGTG GGACTAAGAG GCGTGCAGCT TTCTGGCGGC 
CAGAAACAAA GACTGGCTAT TGCAAGGGCT CTTCTCCGGA AGCCAAAAAT TTTACTGCTG 
GATGAGGCCA CTTCAGCCCT TGATAATGAG AGTGAGAAGG TGGTCCAACA GGCTCTTGAT 
AAAGCCCGGA GAGGGAAGAC CTGCCTAGTG GTGGCTCACA GACTCTCTAC AATACAGAAT 
GCAGATATGA TCGTTGTTCT GCAAAATGGA AGCATCAAGG AGCAGGGAAC TCATCAGGAG 
CTCCTGAGAA ATGGAGATAC ATACTTTAAA TTAGTAGCTG CACATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084237.1
CDS	85..3852
Translation	MANSERTNGLQETNQRYGPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLINGCLVQTNRTKYQNCSQTQEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAKQGLYYSLAMAQDIKKVDEQMESRTCSTAGNASYGSLCDVNSAKAPCTDQLEEAVHHQKTSLPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVTMFEDKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKPTINSCSQSGEKPDTCEGNLEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQVLLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDKARRGKTCLVVAHRLSTIQNADMIVVLQNGSIKEQGTHQELLRNGDTYFKLVAAH

Target ORF information:

RefSeq Version	NM_029961.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029961.2

ORF Insert Sequence:

ATGGCAAATT CTGAAAGAAC CAACGGGTTG CAAGAAACTA ATCAGAGATA TGGACCTCTG 
CAAGAACAAG TGCCTAAAGT GGGAAATCAA GCTGTTGGAC CTATTGAGAT ATTCCGCTTT 
GCTGATAATC TGGACATTGT CCTCATGACT CTGGGAATAT TAGCATCCAT GATAAATGGA 
GCCACCGTTC CTTTAATGTC CCTGGTTTTA GGAGAAATAA GTGATCATTT AATTAATGGA 
TGCCTAGTAC AAACTAACAG AACTAAATAT CAGAACTGTT CTCAGACTCA AGAAAAGCTG 
AATGAAGATA TCATTGTGTT GACTCTATAT TATATTGGAA TAGGAGCAGC TGCCCTCATT 
TTTGGCTATG TACAGATTTC CTTCTGGGTC ATAACTGCAG CCCGGCAAAC CACAAGAATC 
CGAAAACAGT TTTTTCATTC AATTTTGGCA CAAGACATCA GCTGGTTTGA TGGCAGTGAC 
ATCTGTGAAC TTAACACCCG CATGACTGGT GACATCAACA AACTCTGTGA TGGTATTGGA 
GATAAGATCC CTCTGATGTT TCAGAACATA TCTGGGTTTT CTATTGGCCT GGTGATAAGT 
TTGATAAAAA GCTGGAAACT CTCCCTGGTG GTTCTGTCTA CATCTCCTCT CATAATGGCT 
TCATCGGCAC TGTGCTCTAG GATGATTATC TCATTGACCA GCAAGGAGCT GGATGCCTAT 
TCCAAAGCTG GGGCTGTGGC TGAAGAAGCC TTGTCATCAA TCCAAACAGT CACAGCCTTT 
GGAGCCCAAG AGAAAGAAAT TCAAAGGTAT ACACAGCACT TAAAGGACGC AAAGGACGCT 
GGCATAAAGA GGGCTACGGC TTCAAAGCTG TCTCTTGGAG CAGTCTACTT CTTTATGAAT 
GGAGCCTATG GACTGGCTTT TTGGTATGGA ACCTCCTTGA TTTTTGGCGG AGAGCCTGGT 
TACACCATCG GAACTATTCT TGCTGTTTTC TTCAGTGTGA TCCATAGTAG TTACTGCATT 
GGATCTGTAG CCCCTCACCT GGAAACCTTC ACAGTAGCCA GAGGAGCTGC CTTTAATATT 
TTCCAGGTTA TTGATAAGAA ACCCAATATA GATAACTTTT CAACAGCTGG ATTTGTACCT 
GAATGTATAG AAGGAAACAT AGAATTTAAA AATGTTTCTT TCAGCTATCC ATCAAGACCT 
TCTGCCAAGG TTCTGAAAGG TCTCAATCTG AAGATTAAGG CTGGAGAGAC AGTAGCCTTG 
GTTGGTCCCA GTGGCAGTGG CAAGAGTACG ACAGTGCAGC TTCTGCAGAG GCTGTATGAC 
CCAGAGGACG GCTGTATCAC CGTAGATGAG AATGACATCC GAGCCCAAAA CGTGCGACAT 
TACCGAGAGC AAATTGGAGT GGTCAGACAA GAGCCAGTTC TGTTTGGGAC CACCATCGGT 
AACAATATTA AGTTTGGGCG CGAAGGTGTG GGTGAAAAGG AAATGGAACA GGCAGCGAGG 
GAGGCAAACG CCTACGACTT CATAATGGCC TTTCCTAAGA AATTTAATAC ACTAGTAGGG 
GAAAAAGGAG CTCAAATGAG TGGAGGCCAG AAACAGAGGA TTGCCATTGC TCGAGCGCTA 
GTTCGAAACC CCAAAATTCT GATCTTAGAT GAGGCTACAT CTGCCCTGGA CACAGAGAGT 
GAATCACTTG TTCAAACTGC ACTGGAGAAG GCAAGCAAAG GCCGGACTAC AATTGTGGTA 
GCACACAGGC TCTCCACCAT TCGTGGGGCA GACCTGATTG TGACAATGAA GGATGGCATG 
GTGGTGGAGA AAGGGACCCA TGCTGAACTA ATGGCAAAGC AGGGGCTGTA CTACTCCCTC 
GCCATGGCAC AGGATATTAA AAAGGTCGAT GAACAAATGG AATCAAGGAC ATGTTCCACT 
GCAGGAAATG CCAGCTATGG TTCTCTGTGC GATGTGAATA GTGCCAAGGC CCCCTGCACT 
GACCAGCTGG AGGAAGCCGT ACACCATCAA AAGACAAGTC TTCCTGAAGT TTCACTATTA 
AAAATATTTA AATTAAGCAA GTCTGAATGG CCTTTTGTGG TTCTGGGAAC ACTGGCTTCT 
GCTTTAAATG GATCTGTTCA TCCAGTATTT TCCATCATCT TTGGAAAATT AGTCACTATG 
TTTGAAGATA AAAATAAAGC TACATTAAAG CAGGATGCAG AGCTCTACTC CATGATGTTA 
GTCGTCTTGG GCATAGTAGC TCTTGTCACC TACTTGATGC AGGGATTGTT TTATGGCAGA 
GCAGAGGAAA ATTTAGCCAT GAGATTAAGA CACTCGGCAT TCAAAGCCAT GCTCTACCAG 
GATATGGCCT GGTATGATGA TAAAGAGAAC AACACTGGAG CCCTGACCAC AACGTTAGCT 
GTGGATGTAG CACAGATTCA GGGTGCAGCA ACTTCAAGAC TTGGGATCGT AACACAAGAT 
GTGAGCAACA TGAGTCTGTC CATTCTCATC TCCTTCATAT ATGGATGGGA GATGACACTC 
CTGATTCTCA GCTTCGCGCC TGTACTTGCG GTGACAGGAA TGATTCAAAC CGCAGCAATG 
GCTGGCTTTG CCAACAGGGA TAAGCAGGCG CTCAAGCGTG CTGGAAAGAT AGCAACAGAA 
GCTGTGGAGA ACATACGTAC GGTAGTGTCA TTAACAAGAG AGAGAGCCTT TGAGCAAATG 
TATGAGGAGA CACTTCAGAC TCAACACAGA AACGCCTTGA AGAGAGCACA CATCACTGGA 
TGCTGTTATG CAGTCAGCCA TGCTTTTGTG CATTTTGCCC ATGCAGCAGG GTTCCGATTT 
GGAGCCTATT TGATTCAAGC AGGACGGATG ATGCCGGAAG GCATGTTCAT AGTCTTTACC 
GCCATTGCAT ATGGGGCTAT GGCCATTGGA GAAACACTTG TATGGGCTCC TGAATATTCC 
AAAGCCAAAG CTGGAGCTTC GCATCTGTTT GCTTTGCTGA AAAATAAACC AACTATAAAC 
AGCTGCAGTC AAAGTGGGGA AAAACCAGAC ACCTGTGAAG GGAACTTAGA ATTTCGAGAG 
GTCTCTTTCG TCTATCCTTG TCGTCCAGAA GTTCCTGTCC TTCAGAACAT GTCCCTCAGC 
ATTGAGAAAG GGAAGACTGT AGCATTCGTT GGGAGCAGCG GCTGTGGAAA AAGCACATGT 
GTTCAACTGC TGCAAAGATT TTATGACCCC ATGAAAGGAC AAGTGCTGCT TGACGGAGTT 
GATGTAAAAG AATTGAACGT GCAGTGGCTG CGTTCCCAGA CAGCCATCGT CTCCCAAGAG 
CCTGTGCTGT TCAACTGTAG CATCGCTGAG AACATTGCCT ATGGTGATAA CAGCCGCATG 
GTGCCCTTAG AGGAGATCAA AGAGGTCGCA GATGCAGCCA ACATTCATTC TTTCATTGAA 
GGGCTCCCAA GGAAATACAA CACCCTAGTG GGACTAAGAG GCGTGCAGCT TTCTGGCGGC 
CAGAAACAAA GACTGGCTAT TGCAAGGGCT CTTCTCCGGA AGCCAAAAAT TTTACTGCTG 
GATGAGGCCA CTTCAGCCCT TGATAATGAG AGTGAGAAGG TGGTCCAACA GGCTCTTGAT 
AAAGCCCGGA GAGGGAAGAC CTGCCTAGTG GTGGCTCACA GACTCTCTAC AATACAGAAT 
GCAGATATGA TCGTTGTTCT GCAAAATGGA AGCATCAAGG AGCAGGGAAC TCATCAGGAG 
CTCCTGAGAA ATGGAGATAC ATACTTTAAA TTAGTAGCTG CACATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abcb5 ( XM_006516370.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006516433.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X1, mRNA.

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CloneID	OMu48194
Clone ID Related Accession (Same CDS sequence)	XM_006516370.3
Accession Version	XM_006516370.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006516370.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTTCTG GGACCAGACC TCTGCAAGAA CAAGTGCCTA AAGTGGGAAA TCAAGCTGTT 
GGACCTATTG AGATATTCCG CTTTGCTGAT AATCTGGACA TTGTCCTCAT GACTCTGGGA 
ATATTAGCAT CCATGATAAA TGGAGCCACC GTTCCTTTAA TGTCCCTGGT TTTAGGAGAA 
ATAAGTGATC ATTTAATTAA TGGATGCCTA GTACAAACTA ACAGAACTAA ATATCAGAAC 
TGTTCTCAGA CTCAAGAAAA GCTGAATGAA GATATCATTG TGTTGACTCT ATATTATATT 
GGAATAGGAG CAGCTGCCCT CATTTTTGGC TATGTACAGA TTTCCTTCTG GGTCATAACT 
GCAGCCCGGC AAACCACAAG AATCCGAAAA CAGTTTTTTC ATTCAATTTT GGCACAAGAC 
ATCAGCTGGT TTGATGGCAG TGACATCTGT GAACTTAACA CCCGCATGAC TGGTGACATC 
AACAAACTCT GTGATGGTAT TGGAGATAAG ATCCCTCTGA TGTTTCAGAA CATATCTGGG 
TTTTCTATTG GCCTGGTGAT AAGTTTGATA AAAAGCTGGA AACTCTCCCT GGTGGTTCTG 
TCTACATCTC CTCTCATAAT GGCTTCATCG GCACTGTGCT CTAGGATGAT TATCTCATTG 
ACCAGCAAGG AGCTGGATGC CTATTCCAAA GCTGGGGCTG TGGCTGAAGA AGCCTTGTCA 
TCAATCCAAA CAGTCACAGC CTTTGGAGCC CAAGAGAAAG AAATTCAAAG GTATACACAG 
CACTTAAAGG ACGCAAAGGA CGCTGGCATA AAGAGGGCTA CGGCTTCAAA GCTGTCTCTT 
GGAGCAGTCT ACTTCTTTAT GAATGGAGCC TATGGACTGG CTTTTTGGTA TGGAACCTCC 
TTGATTTTTG GCGGAGAGCC TGGTTACACC ATCGGAACTA TTCTTGCTGT TTTCTTCAGT 
GTGATCCATA GTAGTTACTG CATTGGATCT GTAGCCCCTC ACCTGGAAAC CTTCACAGTA 
GCCAGAGGAG CTGCCTTTAA TATTTTCCAG GTTATTGATA AGAAACCCAA TATAGATAAC 
TTTTCAACAG CTGGATTTGT ACCTGAATGT ATAGAAGGAA ACATAGAATT TAAAAATGTT 
TCTTTCAGCT ATCCATCAAG ACCTTCTGCC AAGGTTCTGA AAGGTCTCAA TCTGAAGATT 
AAGGCTGGAG AGACAGTAGC CTTGGTTGGT CCCAGTGGCA GTGGCAAGAG TACGACAGTG 
CAGCTTCTGC AGAGGCTGTA TGACCCAGAG GACGGCTGTA TCACCGTAGA TGAGAATGAC 
ATCCGAGCCC AAAACGTGCG ACATTACCGA GAGCAAATTG GAGTGGTCAG ACAAGAGCCA 
GTTCTGTTTG GGACCACCAT CGGTAACAAT ATTAAGTTTG GGCGCGAAGG TGTGGGTGAA 
AAGGAAATGG AACAGGCAGC GAGGGAGGCA AACGCCTACG ACTTCATAAT GGCCTTTCCT 
AAGAAATTTA ATACACTAGT AGGGGAAAAA GGAGCTCAAA TGAGTGGAGG CCAGAAACAG 
AGGATTGCCA TTGCTCGAGC GCTAGTTCGA AACCCCAAAA TTCTGATCTT AGATGAGGCT 
ACATCTGCCC TGGACACAGA GAGTGAATCA CTTGTTCAAA CTGCACTGGA GAAGGCAAGC 
AAAGGCCGGA CTACAATTGT GGTAGCACAC AGGCTCTCCA CCATTCGTGG GGCAGACCTG 
ATTGTGACAA TGAAGGATGG CATGGTGGTG GAGAAAGGGA CCCATGCTGA ACTAATGGCA 
AAGCAGGGGC TGTACTACTC CCTCGCCATG GCACAGGATA TTAAAAAGGT CGATGAACAA 
ATGGAATCAA GGACATGTTC CACTGCAGGA AATGCCAGCT ATGGTTCTCT GTGCGATGTG 
AATAGTGCCA AGGCCCCCTG CACTGACCAG CTGGAGGAAG CCGTACACCA TCAAAAGACA 
AGTCTTCCTG AAGTTTCACT ATTAAAAATA TTTAAATTAA GCAAGTCTGA ATGGCCTTTT 
GTGGTTCTGG GAACACTGGC TTCTGCTTTA AATGGATCTG TTCATCCAGT ATTTTCCATC 
ATCTTTGGAA AATTAGTCAC TATGTTTGAA GATAAAAATA AAGCTACATT AAAGCAGGAT 
GCAGAGCTCT ACTCCATGAT GTTAGTCGTC TTGGGCATAG TAGCTCTTGT CACCTACTTG 
ATGCAGGGAT TGTTTTATGG CAGAGCAGAG GAAAATTTAG CCATGAGATT AAGACACTCG 
GCATTCAAAG CCATGCTCTA CCAGGATATG GCCTGGTATG ATGATAAAGA GAACAACACT 
GGAGCCCTGA CCACAACGTT AGCTGTGGAT GTAGCACAGA TTCAGGGTGC AGCAACTTCA 
AGACTTGGGA TCGTAACACA AGATGTGAGC AACATGAGTC TGTCCATTCT CATCTCCTTC 
ATATATGGAT GGGAGATGAC ACTCCTGATT CTCAGCTTCG CGCCTGTACT TGCGGTGACA 
GGAATGATTC AAACCGCAGC AATGGCTGGC TTTGCCAACA GGGATAAGCA GGCGCTCAAG 
CGTGCTGGAA AGATAGCAAC AGAAGCTGTG GAGAACATAC GTACGGTAGT GTCATTAACA 
AGAGAGAGAG CCTTTGAGCA AATGTATGAG GAGACACTTC AGACTCAACA CAGAAACGCC 
TTGAAGAGAG CACACATCAC TGGATGCTGT TATGCAGTCA GCCATGCTTT TGTGCATTTT 
GCCCATGCAG CAGGGTTCCG ATTTGGAGCC TATTTGATTC AAGCAGGACG GATGATGCCG 
GAAGGCATGT TCATAGTCTT TACCGCCATT GCATATGGGG CTATGGCCAT TGGAGAAACA 
CTTGTATGGG CTCCTGAATA TTCCAAAGCC AAAGCTGGAG CTTCGCATCT GTTTGCTTTG 
CTGAAAAATA AACCAACTAT AAACAGCTGC AGTCAAAGTG GGGAAAAACC AGACACCTGT 
GAAGGGAACT TAGAATTTCG AGAGGTCTCT TTCGTCTATC CTTGTCGTCC AGAAGTTCCT 
GTCCTTCAGA ACATGTCCCT CAGCATTGAG AAAGGGAAGA CTGTAGCATT CGTTGGGAGC 
AGCGGCTGTG GAAAAAGCAC ATGTGTTCAA CTGCTGCAAA GATTTTATGA CCCCATGAAA 
GGACAAGTGC TGCTTGACGG AGTTGATGTA AAAGAATTGA ACGTGCAGTG GCTGCGTTCC 
CAGACAGCCA TCGTCTCCCA AGAGCCTGTG CTGTTCAACT GTAGCATCGC TGAGAACATT 
GCCTATGGTG ATAACAGCCG CATGGTGCCC TTAGAGGAGA TCAAAGAGGT CGCAGATGCA 
GCCAACATTC ATTCTTTCAT TGAAGGGCTC CCAAGGAAAT ACAACACCCT AGTGGGACTA 
AGAGGCGTGC AGCTTTCTGG CGGCCAGAAA CAAAGACTGG CTATTGCAAG GGCTCTTCTC 
CGGAAGCCAA AAATTTTACT GCTGGATGAG GCCACTTCAG CCCTTGATAA TGAGAGTGAG 
AAGGTGGTCC AACAGGCTCT TGATAAAGCC CGGAGAGGGA AGACCTGCCT AGTGGTGGCT 
CACAGACTCT CTACAATACA GAATGCAGAT ATGATCGTTG TTCTGCAAAA TGGAAGCATC 
AAGGAGCAGG GAACTCATCA GGAGCTCCTG AGAAATGGAG ATACATACTT TAAATTAGTA 
GCTGCACATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006516433.1
CDS	42..3773
Translation	MVSGTRPLQEQVPKVGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVPLMSLVLGEISDHLINGCLVQTNRTKYQNCSQTQEKLNEDIIVLTLYYIGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNIDNFSTAGFVPECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLLQRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGREGVGEKEMEQAAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMAKQGLYYSLAMAQDIKKVDEQMESRTCSTAGNASYGSLCDVNSAKAPCTDQLEEAVHHQKTSLPEVSLLKIFKLSKSEWPFVVLGTLASALNGSVHPVFSIIFGKLVTMFEDKNKATLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEENLAMRLRHSAFKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFIYGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSLTRERAFEQMYEETLQTQHRNALKRAHITGCCYAVSHAFVHFAHAAGFRFGAYLIQAGRMMPEGMFIVFTAIAYGAMAIGETLVWAPEYSKAKAGASHLFALLKNKPTINSCSQSGEKPDTCEGNLEFREVSFVYPCRPEVPVLQNMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQVLLDGVDVKELNVQWLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPRKYNTLVGLRGVQLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKVVQQALDKARRGKTCLVVAHRLSTIQNADMIVVLQNGSIKEQGTHQELLRNGDTYFKLVAAH

Target ORF information:

RefSeq Version	XM_006516370.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 5 (Abcb5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516370.3

ORF Insert Sequence:

ATGGTTTCTG GGACCAGACC TCTGCAAGAA CAAGTGCCTA AAGTGGGAAA TCAAGCTGTT 
GGACCTATTG AGATATTCCG CTTTGCTGAT AATCTGGACA TTGTCCTCAT GACTCTGGGA 
ATATTAGCAT CCATGATAAA TGGAGCCACC GTTCCTTTAA TGTCCCTGGT TTTAGGAGAA 
ATAAGTGATC ATTTAATTAA TGGATGCCTA GTACAAACTA ACAGAACTAA ATATCAGAAC 
TGTTCTCAGA CTCAAGAAAA GCTGAATGAA GATATCATTG TGTTGACTCT ATATTATATT 
GGAATAGGAG CAGCTGCCCT CATTTTTGGC TATGTACAGA TTTCCTTCTG GGTCATAACT 
GCAGCCCGGC AAACCACAAG AATCCGAAAA CAGTTTTTTC ATTCAATTTT GGCACAAGAC 
ATCAGCTGGT TTGATGGCAG TGACATCTGT GAACTTAACA CCCGCATGAC TGGTGACATC 
AACAAACTCT GTGATGGTAT TGGAGATAAG ATCCCTCTGA TGTTTCAGAA CATATCTGGG 
TTTTCTATTG GCCTGGTGAT AAGTTTGATA AAAAGCTGGA AACTCTCCCT GGTGGTTCTG 
TCTACATCTC CTCTCATAAT GGCTTCATCG GCACTGTGCT CTAGGATGAT TATCTCATTG 
ACCAGCAAGG AGCTGGATGC CTATTCCAAA GCTGGGGCTG TGGCTGAAGA AGCCTTGTCA 
TCAATCCAAA CAGTCACAGC CTTTGGAGCC CAAGAGAAAG AAATTCAAAG GTATACACAG 
CACTTAAAGG ACGCAAAGGA CGCTGGCATA AAGAGGGCTA CGGCTTCAAA GCTGTCTCTT 
GGAGCAGTCT ACTTCTTTAT GAATGGAGCC TATGGACTGG CTTTTTGGTA TGGAACCTCC 
TTGATTTTTG GCGGAGAGCC TGGTTACACC ATCGGAACTA TTCTTGCTGT TTTCTTCAGT 
GTGATCCATA GTAGTTACTG CATTGGATCT GTAGCCCCTC ACCTGGAAAC CTTCACAGTA 
GCCAGAGGAG CTGCCTTTAA TATTTTCCAG GTTATTGATA AGAAACCCAA TATAGATAAC 
TTTTCAACAG CTGGATTTGT ACCTGAATGT ATAGAAGGAA ACATAGAATT TAAAAATGTT 
TCTTTCAGCT ATCCATCAAG ACCTTCTGCC AAGGTTCTGA AAGGTCTCAA TCTGAAGATT 
AAGGCTGGAG AGACAGTAGC CTTGGTTGGT CCCAGTGGCA GTGGCAAGAG TACGACAGTG 
CAGCTTCTGC AGAGGCTGTA TGACCCAGAG GACGGCTGTA TCACCGTAGA TGAGAATGAC 
ATCCGAGCCC AAAACGTGCG ACATTACCGA GAGCAAATTG GAGTGGTCAG ACAAGAGCCA 
GTTCTGTTTG GGACCACCAT CGGTAACAAT ATTAAGTTTG GGCGCGAAGG TGTGGGTGAA 
AAGGAAATGG AACAGGCAGC GAGGGAGGCA AACGCCTACG ACTTCATAAT GGCCTTTCCT 
AAGAAATTTA ATACACTAGT AGGGGAAAAA GGAGCTCAAA TGAGTGGAGG CCAGAAACAG 
AGGATTGCCA TTGCTCGAGC GCTAGTTCGA AACCCCAAAA TTCTGATCTT AGATGAGGCT 
ACATCTGCCC TGGACACAGA GAGTGAATCA CTTGTTCAAA CTGCACTGGA GAAGGCAAGC 
AAAGGCCGGA CTACAATTGT GGTAGCACAC AGGCTCTCCA CCATTCGTGG GGCAGACCTG 
ATTGTGACAA TGAAGGATGG CATGGTGGTG GAGAAAGGGA CCCATGCTGA ACTAATGGCA 
AAGCAGGGGC TGTACTACTC CCTCGCCATG GCACAGGATA TTAAAAAGGT CGATGAACAA 
ATGGAATCAA GGACATGTTC CACTGCAGGA AATGCCAGCT ATGGTTCTCT GTGCGATGTG 
AATAGTGCCA AGGCCCCCTG CACTGACCAG CTGGAGGAAG CCGTACACCA TCAAAAGACA 
AGTCTTCCTG AAGTTTCACT ATTAAAAATA TTTAAATTAA GCAAGTCTGA ATGGCCTTTT 
GTGGTTCTGG GAACACTGGC TTCTGCTTTA AATGGATCTG TTCATCCAGT ATTTTCCATC 
ATCTTTGGAA AATTAGTCAC TATGTTTGAA GATAAAAATA AAGCTACATT AAAGCAGGAT 
GCAGAGCTCT ACTCCATGAT GTTAGTCGTC TTGGGCATAG TAGCTCTTGT CACCTACTTG 
ATGCAGGGAT TGTTTTATGG CAGAGCAGAG GAAAATTTAG CCATGAGATT AAGACACTCG 
GCATTCAAAG CCATGCTCTA CCAGGATATG GCCTGGTATG ATGATAAAGA GAACAACACT 
GGAGCCCTGA CCACAACGTT AGCTGTGGAT GTAGCACAGA TTCAGGGTGC AGCAACTTCA 
AGACTTGGGA TCGTAACACA AGATGTGAGC AACATGAGTC TGTCCATTCT CATCTCCTTC 
ATATATGGAT GGGAGATGAC ACTCCTGATT CTCAGCTTCG CGCCTGTACT TGCGGTGACA 
GGAATGATTC AAACCGCAGC AATGGCTGGC TTTGCCAACA GGGATAAGCA GGCGCTCAAG 
CGTGCTGGAA AGATAGCAAC AGAAGCTGTG GAGAACATAC GTACGGTAGT GTCATTAACA 
AGAGAGAGAG CCTTTGAGCA AATGTATGAG GAGACACTTC AGACTCAACA CAGAAACGCC 
TTGAAGAGAG CACACATCAC TGGATGCTGT TATGCAGTCA GCCATGCTTT TGTGCATTTT 
GCCCATGCAG CAGGGTTCCG ATTTGGAGCC TATTTGATTC AAGCAGGACG GATGATGCCG 
GAAGGCATGT TCATAGTCTT TACCGCCATT GCATATGGGG CTATGGCCAT TGGAGAAACA 
CTTGTATGGG CTCCTGAATA TTCCAAAGCC AAAGCTGGAG CTTCGCATCT GTTTGCTTTG 
CTGAAAAATA AACCAACTAT AAACAGCTGC AGTCAAAGTG GGGAAAAACC AGACACCTGT 
GAAGGGAACT TAGAATTTCG AGAGGTCTCT TTCGTCTATC CTTGTCGTCC AGAAGTTCCT 
GTCCTTCAGA ACATGTCCCT CAGCATTGAG AAAGGGAAGA CTGTAGCATT CGTTGGGAGC 
AGCGGCTGTG GAAAAAGCAC ATGTGTTCAA CTGCTGCAAA GATTTTATGA CCCCATGAAA 
GGACAAGTGC TGCTTGACGG AGTTGATGTA AAAGAATTGA ACGTGCAGTG GCTGCGTTCC 
CAGACAGCCA TCGTCTCCCA AGAGCCTGTG CTGTTCAACT GTAGCATCGC TGAGAACATT 
GCCTATGGTG ATAACAGCCG CATGGTGCCC TTAGAGGAGA TCAAAGAGGT CGCAGATGCA 
GCCAACATTC ATTCTTTCAT TGAAGGGCTC CCAAGGAAAT ACAACACCCT AGTGGGACTA 
AGAGGCGTGC AGCTTTCTGG CGGCCAGAAA CAAAGACTGG CTATTGCAAG GGCTCTTCTC 
CGGAAGCCAA AAATTTTACT GCTGGATGAG GCCACTTCAG CCCTTGATAA TGAGAGTGAG 
AAGGTGGTCC AACAGGCTCT TGATAAAGCC CGGAGAGGGA AGACCTGCCT AGTGGTGGCT 
CACAGACTCT CTACAATACA GAATGCAGAT ATGATCGTTG TTCTGCAAAA TGGAAGCATC 
AAGGAGCAGG GAACTCATCA GGAGCTCCTG AGAAATGGAG ATACATACTT TAAATTAGTA 
GCTGCACATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.
PLoS genetics14(1)e1007145(2018 01)
King R,Struebing FL,Li Y,Wang J,Koch AA,Cooke Bailey JN,Gharahkhani P,,,MacGregor S,Allingham RR,Hauser MA,Wiggs JL,Geisert EE

Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells.
BMC pharmacology & toxicology1637(2015 Dec)
Kondo S,Hongama K,Hanaya K,Yoshida R,Kawanobe T,Katayama K,Noguchi K,Sugimoto Y

The role of Abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans.
PLoS medicine12(2)e1001782(2015 Feb)
Zheng M,Zhang H,Dill DL,Clark JD,Tu S,Yablonovitch AL,Tan MH,Zhang R,Rujescu D,Wu M,Tessarollo L,Vieira W,Gottesman MM,Deng S,Eberlin LS,Zare RN,Billard JM,Gillet JP,Li JB,Peltz G

ABCB5 is a limbal stem cell gene required for corneal development and repair.
Nature511(7509)353-7(2014 Jul)
Ksander BR,Kolovou PE,Wilson BJ,Saab KR,Guo Q,Ma J,McGuire SP,Gregory MS,Vincent WJ,Perez VL,Cruz-Guilloty F,Kao WW,Call MK,Tucker BA,Zhan Q,Murphy GF,Lathrop KL,Alt C,Mortensen LJ,Lin CP,Zieske JD,Frank MH,Frank NY

The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo.
The Journal of biological chemistry287(17)13633-43(2012 Apr)
Linley AJ,Mathieu MG,Miles AK,Rees RC,McArdle SE,Regad T

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Abcb5 cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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