Lrrc15 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrrc15
Entrez Gene ID	74488
Full Name	leucine rich repeat containing 15
Synonyms	5430427N11Rik,LIB
General protein information	Preferred Names leucine rich repeat containing 15 Names leucine-rich repeat-containing protein 15
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 B2

mRNA and Protein(s)

mRNA	Protein	Name
NM_028973.2	NP_083249.1	leucine-rich repeat-containing protein 15 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LRRC15	NP_001128529.2
Pan troglodytes (chimpanzee)	LRRC15	XP_001147414.2
Macaca mulatta (Rhesus monkey)	LRRC15	XP_001095878.2
Gallus gallus (chicken)	LRRC15	XP_004943388.1
Danio rerio (zebrafish)	lrrc15	NP_001074151.1
Caenorhabditis elegans (roundworm)	lron-2	NP_505402.1
Canis lupus familiaris (dog)	LRRC15	XP_005639692.1
Mus musculus (house mouse)	Lrrc15	NP_083249.1
Caenorhabditis elegans (roundworm)	lron-1	NP_510424.4
Xenopus tropicalis (tropical clawed frog)	lrrc15	XP_002937882.2
Rattus norvegicus (Norway rat)	Lrrc15	NP_659551.1
Bos taurus (cattle)	LRRC15	XP_003585707.1

Gene Ontology
Bibliography

Related articles in PubMed

LRRC15 promotes osteogenic differentiation of mesenchymal stem cells by modulating p65 cytoplasmic/nuclear translocation.
Wang Y, Liu Y, Zhang M, Lv L, Zhang X, Zhang P, Zhou Y
Stem cell research & therapy9(1)65(2018 03)

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Mitochondrial retention of Opa1 is required for mouse embryogenesis.
Moore BA, Gonzalez Aviles GD, Larkins CE, Hillman MJ, Caspary T
Mammalian genome : official journal of the International Mammalian Genome Society21(7-8)350-60(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lrrc15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrrc15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06376	NM_028973.2 Latest version!	Mus musculus leucine rich repeat containing 15 (Lrrc15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$342.30 $489.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrrc15 ( NM_028973.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083249.1 Mus musculus leucine rich repeat containing 15 (Lrrc15), mRNA.

Price & Availability↑

CloneID	OMu06376
Clone ID Related Accession (Same CDS sequence)	NM_028973.2
Accession Version	NM_028973.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550505600000
Organism	Mus musculus(house mouse)
Product	leucine-rich repeat-containing protein 15 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK017350.1, BC050245.1 and BX522800.1. On Apr 15, 2009 this sequence version replaced NM_028973.1. ##Evidence-Data-START## Transcript exon combination :: AK017350.1, BC050245.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGCTGA AACATTATCT CCTTTTGCTG GTGAGCTGCC AGGCCTGGGC TGCAGGTTTG 
GCCTACTATG GCTGCCCCAG CGAATGTACC TGTTCCCGGG CCTCCCAGGT AGAGTGCACA 
GGGGCACAAA TTGTGGCGAT GCCTTCCCCT CTGCCCTGGA ATGCTATGAG CCTGCAGATC 
CTTAACACAC ACATCACCGA ACTCCCCGAG GACAAGTTCC TCAACATTTC AGCCCTCATC 
GCCCTGAAGA TGGAGAAGAA CGAGCTGGCC AACATCATGC CAGGTGCCTT CCGCAATCTG 
GGCTCGCTGC GTCACCTCAG CCTTGCCAAC AACAAACTAA AGAACCTGCC CGTTAGGCTC 
TTCCAGGATG TGAACAATCT GGAGACCCTC CTGCTGTCCA ATAACCAGCT GGTGCAGATC 
CAGCCGGCCC AGTTCTCCCA GTTTAGTAAT CTTAAGGAAC TCCAGTTGTA TGGCAACAAT 
CTGGAATACA TCCCCGAAGG AGTCTTTGAC CACCTGGTAG GTCTCACCAA ACTCAACCTG 
GGCAACAACG GCTTCACCCA CCTATCCCCT AGGGTCTTTC AGCATCTGGG CAACCTCCAG 
GTGCTTCGGC TATATGAGAA CAGGCTTTCA GACATCCCCA TGGGCACTTT TGATGCACTT 
GGCAACCTCC AGGAGCTGGC CCTCCAAGAG AACCAGATTG GCACCCTCTC CCCTGGCTTG 
TTCCACAATA ACCGTAACCT CCAGAGACTG TATCTATCCA ACAACCACAT CTCACATCTG 
CCCCCTGGCA TCTTCATGCA GCTGCCCCAC CTTAACAAGC TCACACTCTT TGGGAATTCC 
CTGAAGGAGC TTTCCCCGGG GGTCTTTGGG CCCATGCCCA ACCTGAGGGA GCTTTGGCTC 
TACAACAATC ACATTACCTC CCTCCCTGAC AATGCCTTCA GCCACCTGAA CCAGTTGCAG 
GTTCTGATTC TTAGTCACAA CCAGCTCAGT TACATCTCCC CAGGAGCCTT CAATGGGCTG 
ACGAATCTCC GAGAACTGTC CCTCCACACC AATGCTCTAC AGGACCTGGA TGGGAATGTC 
TTCCGATCAC TGGCCAACCT GAGGAACGTC TCACTCCAGA ATAACCGCCT TCGACAGCTC 
CCTGGCAGCA TCTTCGCCAA CGTCAATGGT CTCATGACCA TCCAACTGCA GAACAACAAT 
CTAGAGAACT TGCCTCTGGG CATCTTTGAT CACTTAGGGA ACCTGTGTGA GCTTCGTCTC 
TATGACAACC CCTGGAGATG TGACTCAAAC ATCCTCCCAC TTCATGACTG GCTCATTCTC 
AACAGAGCCA GGTTGGGGAC AGACACTCTT CCAGTGTGTT CCAGTCCAGC CAGTGTCCGA 
GGCCAGTCCC TTGTCATCAT CAATGTCAAT TTCCCTGGAC CCAGTGTCCA GGGCCCAGAA 
ACCCCTGAAG TATCTAGCTA CCCAGATACA TCCAGCTATC CTGACAGCAC ATCCATTTCT 
TCTACCACAG AGATCACCAG GTCTACCGAT GATGACTACA CCGATCTAAA CACCATCGAA 
CCCATTGATG ACCGCAATAC ATGGGGCATG ACTGATGCCC AGAGTGGGCT GGCCATTGCT 
GCCATTGTGA TTGGCATCAT AGCTTTGGCC TGTTCCCTCG CTGCCTGTAT CTGCTGCTGC 
TGCTGCAAAA AGAGGAGCCA GGCAGTCCTG ATGCAGATGA AGGCTCCCAA TGAGTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083249.1
CDS	91..1830
Translation	MPLKHYLLLLVSCQAWAAGLAYYGCPSECTCSRASQVECTGAQIVAMPSPLPWNAMSLQILNTHITELPEDKFLNISALIALKMEKNELANIMPGAFRNLGSLRHLSLANNKLKNLPVRLFQDVNNLETLLLSNNQLVQIQPAQFSQFSNLKELQLYGNNLEYIPEGVFDHLVGLTKLNLGNNGFTHLSPRVFQHLGNLQVLRLYENRLSDIPMGTFDALGNLQELALQENQIGTLSPGLFHNNRNLQRLYLSNNHISHLPPGIFMQLPHLNKLTLFGNSLKELSPGVFGPMPNLRELWLYNNHITSLPDNAFSHLNQLQVLILSHNQLSYISPGAFNGLTNLRELSLHTNALQDLDGNVFRSLANLRNVSLQNNRLRQLPGSIFANVNGLMTIQLQNNNLENLPLGIFDHLGNLCELRLYDNPWRCDSNILPLHDWLILNRARLGTDTLPVCSSPASVRGQSLVIINVNFPGPSVQGPETPEVSSYPDTSSYPDSTSISSTTEITRSTDDDYTDLNTIEPIDDRNTWGMTDAQSGLAIAAIVIGIIALACSLAACICCCCCKKRSQAVLMQMKAPNEC

Target ORF information:

RefSeq Version	NM_028973.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine rich repeat containing 15 (Lrrc15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028973.2

ORF Insert Sequence:

ATGCCGCTGA AACATTATCT CCTTTTGCTG GTGAGCTGCC AGGCCTGGGC TGCAGGTTTG 
GCCTACTATG GCTGCCCCAG CGAATGTACC TGTTCCCGGG CCTCCCAGGT AGAGTGCACA 
GGGGCACAAA TTGTGGCGAT GCCTTCCCCT CTGCCCTGGA ATGCTATGAG CCTGCAGATC 
CTTAACACAC ACATCACCGA ACTCCCCGAG GACAAGTTCC TCAACATTTC AGCCCTCATC 
GCCCTGAAGA TGGAGAAGAA CGAGCTGGCC AACATCATGC CAGGTGCCTT CCGCAATCTG 
GGCTCGCTGC GTCACCTCAG CCTTGCCAAC AACAAACTAA AGAACCTGCC CGTTAGGCTC 
TTCCAGGATG TGAACAATCT GGAGACCCTC CTGCTGTCCA ATAACCAGCT GGTGCAGATC 
CAGCCGGCCC AGTTCTCCCA GTTTAGTAAT CTTAAGGAAC TCCAGTTGTA TGGCAACAAT 
CTGGAATACA TCCCCGAAGG AGTCTTTGAC CACCTGGTAG GTCTCACCAA ACTCAACCTG 
GGCAACAACG GCTTCACCCA CCTATCCCCT AGGGTCTTTC AGCATCTGGG CAACCTCCAG 
GTGCTTCGGC TATATGAGAA CAGGCTTTCA GACATCCCCA TGGGCACTTT TGATGCACTT 
GGCAACCTCC AGGAGCTGGC CCTCCAAGAG AACCAGATTG GCACCCTCTC CCCTGGCTTG 
TTCCACAATA ACCGTAACCT CCAGAGACTG TATCTATCCA ACAACCACAT CTCACATCTG 
CCCCCTGGCA TCTTCATGCA GCTGCCCCAC CTTAACAAGC TCACACTCTT TGGGAATTCC 
CTGAAGGAGC TTTCCCCGGG GGTCTTTGGG CCCATGCCCA ACCTGAGGGA GCTTTGGCTC 
TACAACAATC ACATTACCTC CCTCCCTGAC AATGCCTTCA GCCACCTGAA CCAGTTGCAG 
GTTCTGATTC TTAGTCACAA CCAGCTCAGT TACATCTCCC CAGGAGCCTT CAATGGGCTG 
ACGAATCTCC GAGAACTGTC CCTCCACACC AATGCTCTAC AGGACCTGGA TGGGAATGTC 
TTCCGATCAC TGGCCAACCT GAGGAACGTC TCACTCCAGA ATAACCGCCT TCGACAGCTC 
CCTGGCAGCA TCTTCGCCAA CGTCAATGGT CTCATGACCA TCCAACTGCA GAACAACAAT 
CTAGAGAACT TGCCTCTGGG CATCTTTGAT CACTTAGGGA ACCTGTGTGA GCTTCGTCTC 
TATGACAACC CCTGGAGATG TGACTCAAAC ATCCTCCCAC TTCATGACTG GCTCATTCTC 
AACAGAGCCA GGTTGGGGAC AGACACTCTT CCAGTGTGTT CCAGTCCAGC CAGTGTCCGA 
GGCCAGTCCC TTGTCATCAT CAATGTCAAT TTCCCTGGAC CCAGTGTCCA GGGCCCAGAA 
ACCCCTGAAG TATCTAGCTA CCCAGATACA TCCAGCTATC CTGACAGCAC ATCCATTTCT 
TCTACCACAG AGATCACCAG GTCTACCGAT GATGACTACA CCGATCTAAA CACCATCGAA 
CCCATTGATG ACCGCAATAC ATGGGGCATG ACTGATGCCC AGAGTGGGCT GGCCATTGCT 
GCCATTGTGA TTGGCATCAT AGCTTTGGCC TGTTCCCTCG CTGCCTGTAT CTGCTGCTGC 
TGCTGCAAAA AGAGGAGCCA GGCAGTCCTG ATGCAGATGA AGGCTCCCAA TGAGTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LRRC15 promotes osteogenic differentiation of mesenchymal stem cells by modulating p65 cytoplasmic/nuclear translocation.
Stem cell research & therapy9(1)65(2018 03)
Wang Y,Liu Y,Zhang M,Lv L,Zhang X,Zhang P,Zhou Y

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
PloS one12(7)e0180682(2017)
Sundberg JP,Dadras SS,Silva KA,Kennedy VE,Garland G,Murray SA,Sundberg BA,Schofield PN,Pratt CH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Mitochondrial retention of Opa1 is required for mouse embryogenesis.
Mammalian genome : official journal of the International Mammalian Genome Society21(7-8)350-60(2010 Aug)
Moore BA,Gonzalez Aviles GD,Larkins CE,Hillman MJ,Caspary T

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Lrrc15 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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