| Gene Symbol | Cltb |
| Entrez Gene ID | 74325 |
| Full Name | clathrin, light polypeptide (Lcb) |
| Synonyms | 2310046E19Rik,lcb |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Cltb cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Cltb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cltb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu06259 Clone ID Related Accession (Same CDS sequence) NM_028870.4 Accession Version NM_028870.4 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 636bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1571587200000 Organism Mus musculus(house mouse) Product clathrin light chain B isoform b Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY256386.1, BY075785.1, AK159480.1, BQ173953.1 and BE991851.1. On Nov 30, 2016 this sequence version replaced NM_028870.3. Transcript Variant: This variant (1) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: AK146816.1, AK167531.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139, SAMN01164140 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601ATGGCTGAGG ACTTCGGCTT CTTCTCATCG TCGGAGAGCG GGGCCCCGGA GGCCGCCGAG
GAGGACCCAG CGGCCGCCTT CCTGGCCCAG CAGGAAAGCG AGATTGCTGG CATCGAGAAT
GACCCGGGTT TCGGGGCACC TGCCGCCAGC CAGGTGGCCT CTGCGCAGCC GGGACTCGCG
AGCGGGGCTG GTTCAGAGGA CATGAGTACT ACAGTCAATG GAGATGTGTT TCAGGAGGCT
AACGGGCCTG CCGATGGCTA CGCTGCGATT GCCCAGGCGG ACAGGTTGAC TCAGGAGCCC
GAGAGCATCC GGAAGTGGAG AGAGGAGCAG AAGAAAAGGC TGCAGGAGTT AGACGCTGCC
TCGAAGGTGA CCGAACAGGA GTGGCGGGAG AAGGCCAAGA AAGACCTGGA GGAGTGGAAC
CAGCGCCAAA GTGAACAGGT TGAGAAGAAC AAGATCAACA ACAGGGCATC GGAAGAGGCT
TTTGTGAAAG AATCCAAGGA GGAGACCCCG GGCACAGAGT GGGAGAAGGT AGCCCAGCTG
TGTGACTTCA ATCCCAAGAG CAGCAAGCAG TGTAAAGATG TGTCCCGCCT GCGCTCGGTG
CTCATGTCCC TGAAGCAAAC ACCACTGTCC CGCTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_083146.1 CDS 110..745 Translation 
Target ORF information:
RefSeq Version NM_028870.4 Organism Mus musculus(house mouse) Definition Mus musculus clathrin, light polypeptide (Lcb) (Cltb), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_028870.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601ATGGCTGAGG ACTTCGGCTT CTTCTCATCG TCGGAGAGCG GGGCCCCGGA GGCCGCCGAG
GAGGACCCAG CGGCCGCCTT CCTGGCCCAG CAGGAAAGCG AGATTGCTGG CATCGAGAAT
GACCCGGGTT TCGGGGCACC TGCCGCCAGC CAGGTGGCCT CTGCGCAGCC GGGACTCGCG
AGCGGGGCTG GTTCAGAGGA CATGAGTACT ACAGTCAATG GAGATGTGTT TCAGGAGGCT
AACGGGCCTG CCGATGGCTA CGCTGCGATT GCCCAGGCGG ACAGGTTGAC TCAGGAGCCC
GAGAGCATCC GGAAGTGGAG AGAGGAGCAG AAGAAAAGGC TGCAGGAGTT AGACGCTGCC
TCGAAGGTGA CCGAACAGGA GTGGCGGGAG AAGGCCAAGA AAGACCTGGA GGAGTGGAAC
CAGCGCCAAA GTGAACAGGT TGAGAAGAAC AAGATCAACA ACAGGGCATC GGAAGAGGCT
TTTGTGAAAG AATCCAAGGA GGAGACCCCG GGCACAGAGT GGGAGAAGGT AGCCCAGCTG
TGTGACTTCA ATCCCAAGAG CAGCAAGCAG TGTAAAGATG TGTCCCGCCT GCGCTCGGTG
CTCATGTCCC TGAAGCAAAC ACCACTGTCC CGCTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OMu48883 Clone ID Related Accession (Same CDS sequence) NM_001347512.1 Accession Version NM_001347512.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 690bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577462400000 Organism Mus musculus(house mouse) Product clathrin light chain B isoform a Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY256386.1, BY075785.1, BC070404.1, AK167531.1, BQ173953.1 and BE991851.1. On Nov 30, 2016 this sequence version replaced XM_006517418.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: BC070404.1, BQ177244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661ATGGCTGAGG ACTTCGGCTT CTTCTCATCG TCGGAGAGCG GGGCCCCGGA GGCCGCCGAG
GAGGACCCAG CGGCCGCCTT CCTGGCCCAG CAGGAAAGCG AGATTGCTGG CATCGAGAAT
GACCCGGGTT TCGGGGCACC TGCCGCCAGC CAGGTGGCCT CTGCGCAGCC GGGACTCGCG
AGCGGGGCTG GTTCAGAGGA CATGAGTACT ACAGTCAATG GAGATGTGTT TCAGGAGGCT
AACGGGCCTG CCGATGGCTA CGCTGCGATT GCCCAGGCGG ACAGGTTGAC TCAGGAGCCC
GAGAGCATCC GGAAGTGGAG AGAGGAGCAG AAGAAAAGGC TGCAGGAGTT AGACGCTGCC
TCGAAGGTGA CCGAACAGGA GTGGCGGGAG AAGGCCAAGA AAGACCTGGA GGAGTGGAAC
CAGCGCCAAA GTGAACAGGT TGAGAAGAAC AAGATCAACA ACAGGATCGC TGACAAAGCG
TTCTACCAGC AGCCAGATGC TGATACCATT GGCTATGTGG CATCGGAAGA GGCTTTTGTG
AAAGAATCCA AGGAGGAGAC CCCGGGCACA GAGTGGGAGA AGGTAGCCCA GCTGTGTGAC
TTCAATCCCA AGAGCAGCAA GCAGTGTAAA GATGTGTCCC GCCTGCGCTC GGTGCTCATG
TCCCTGAAGC AAACACCACT GTCCCGCTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001334441.1 CDS 110..799 Translation
Target ORF information:
RefSeq Version NM_001347512.1 Organism Mus musculus(house mouse) Definition Mus musculus clathrin, light polypeptide (Lcb) (Cltb), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_001347512.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661ATGGCTGAGG ACTTCGGCTT CTTCTCATCG TCGGAGAGCG GGGCCCCGGA GGCCGCCGAG
GAGGACCCAG CGGCCGCCTT CCTGGCCCAG CAGGAAAGCG AGATTGCTGG CATCGAGAAT
GACCCGGGTT TCGGGGCACC TGCCGCCAGC CAGGTGGCCT CTGCGCAGCC GGGACTCGCG
AGCGGGGCTG GTTCAGAGGA CATGAGTACT ACAGTCAATG GAGATGTGTT TCAGGAGGCT
AACGGGCCTG CCGATGGCTA CGCTGCGATT GCCCAGGCGG ACAGGTTGAC TCAGGAGCCC
GAGAGCATCC GGAAGTGGAG AGAGGAGCAG AAGAAAAGGC TGCAGGAGTT AGACGCTGCC
TCGAAGGTGA CCGAACAGGA GTGGCGGGAG AAGGCCAAGA AAGACCTGGA GGAGTGGAAC
CAGCGCCAAA GTGAACAGGT TGAGAAGAAC AAGATCAACA ACAGGATCGC TGACAAAGCG
TTCTACCAGC AGCCAGATGC TGATACCATT GGCTATGTGG CATCGGAAGA GGCTTTTGTG
AAAGAATCCA AGGAGGAGAC CCCGGGCACA GAGTGGGAGA AGGTAGCCCA GCTGTGTGAC
TTCAATCCCA AGAGCAGCAA GCAGTGTAAA GATGTGTCCC GCCTGCGCTC GGTGCTCATG
TCCCTGAAGC AAACACCACT GTCCCGCTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Assembly of the cochlear gap junction macromolecular complex requires connexin 26.
The Journal of clinical investigation124(4)1598-607(2014 Apr)
Kamiya K,Yum SW,Kurebayashi N,Muraki M,Ogawa K,Karasawa K,Miwa A,Guo X,Gotoh S,Sugitani Y,Yamanaka H,Ito-Kawashima S,Iizuka T,Sakurai T,Noda T,Minowa O,Ikeda K
Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.
PloS one9(2)e89020(2014)
Storbeck M,Hupperich K,Gaspar JA,Meganathan K,Martínez Carrera L,Wirth R,Sachinidis A,Wirth B
The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia.
Journal of cell science123(Pt 10)1785-95(2010 May)
Molla-Herman A,Ghossoub R,Blisnick T,Meunier A,Serres C,Silbermann F,Emmerson C,Romeo K,Bourdoncle P,Schmitt A,Saunier S,Spassky N,Bastin P,Benmerah A
Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice.
Proceedings of the National Academy of Sciences of the United States of America106(33)13838-43(2009 Aug)
Chen H,Ko G,Zatti A,Di Giacomo G,Liu L,Raiteri E,Perucco E,Collesi C,Min W,Zeiss C,De Camilli P,Cremona O
A B-Myb complex containing clathrin and filamin is required for mitotic spindle function.
The EMBO journal27(13)1852-62(2008 Jul)
Yamauchi T,Ishidao T,Nomura T,Shinagawa T,Tanaka Y,Yonemura S,Ishii S
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