Acsl3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Acsl3
Entrez Gene ID	74205
Full Name	acyl-CoA synthetase long-chain family member 3
Synonyms	2610510B12Rik,Acs3,C85929,Facl3,Pro2194
General protein information	Preferred Names acyl-CoA synthetase long-chain family member 3 Names long-chain-fatty-acid--CoA ligase 3 LACS 3 fatty acid Coenzyme A ligase, long chain 3 long-chain acyl-CoA synthetase 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 C4\|1 40.84 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_028817.3	NP_083093.2	long-chain-fatty-acid--CoA ligase 3 isoform a
NM_001033606.2	NP_001028778.2	long-chain-fatty-acid--CoA ligase 3 isoform a
NM_001136222.1	NP_001129694.1	long-chain-fatty-acid--CoA ligase 3 isoform b

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ACSL3	XP_001166511.1
Macaca mulatta (Rhesus monkey)	ACSL3	XP_001108365.2
Arabidopsis thaliana (thale cress)	LACS8	NP_178516.1
Gallus gallus (chicken)	ACSL3	XP_422625.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003623	XP_003436540.1
Xenopus tropicalis (tropical clawed frog)	acsl4	NP_001090679.1
Canis lupus familiaris (dog)	ACSL3	XP_851617.1
Mus musculus (house mouse)	Acsl3	NP_083093.2
Danio rerio (zebrafish)	acsl3a	NP_001038593.1
Oryza sativa (rice)	Os05g0317200	NP_001055177.1
Bos taurus (cattle)	ACSL3	NP_001192397.1
Homo sapiens (human)	ACSL3	NP_976251.1
Rattus norvegicus (Norway rat)	Acsl3	NP_476448.1
Drosophila melanogaster (fruit fly)	Acsl	NP_724695.1
Danio rerio (zebrafish)	acsl3b	NP_001139404.1

Gene Ontology
Bibliography

Related articles in PubMed

Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Menendez-Montes I, Escobar B, Palacios B, Gómez MJ, Izquierdo-Garcia JL, Flores L, Jiménez-Borreguero LJ, Aragones J, Ruiz-Cabello J, Torres M, Martin-Puig S
Developmental cell39(6)724-739(2016 12)

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, Yang C, Batten K, Huffman KE, Liu J, Tang X, Rodriguez-Canales J, Kalhor N, Shay JW, Minna JD, McDonald J, Wistuba II, DeBerardinis RJ, Scaglioni PP
Cell reports16(6)1614-1628(2016 08)

Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity.
Bu SY, Mashek MT, Mashek DG
The Journal of biological chemistry284(44)30474-83(2009 Oct)

Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.
de Jong H, Neal AC, Coleman RA, Lewin TM
Biochimica et biophysica acta1771(1)75-82(2007 Jan)

Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells.
Pei Z, Fraisl P, Berger J, Jia Z, Forss-Petter S, Watkins PA
The Journal of biological chemistry279(52)54454-62(2004 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Acsl3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Acsl3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu21544	NM_001033606.2 Latest version!	Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu21544	NM_028817.3 Latest version!	Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu21545	NM_001136222.1 Latest version!	Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Acsl3 ( NM_028817.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083093.2 Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu21544
Clone ID Related Accession (Same CDS sequence)	NM_028817.3 , NM_001033606.2
Accession Version	NM_028817.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	long-chain-fatty-acid--CoA ligase 3 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK161708.1, AK046000.1 and CK379747.1. On Oct 28, 2008 this sequence version replaced NM_028817.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 2 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: AK161708.1, AK166723.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATAACC ACGTATCTTC AACACCATCA ACCATGAAGC TAAAACAAAC CATCAACCCC 
ATACTTTTAT ATTTCATACA TTTTATAATA TCACTCTATA CTATTTTAAC ATACATCCCA 
TTTTATTTTT TGTGTGAGTC AAAACAAGAG AAACCAAACC AAATTAAAGC AAAACCTGTC 
AGTTCCAAAC CGGACTCTGC ATACAGATCT ATCAACAGTG TGGATGGCTT GGCTTCAGTG 
CTGTATCCTG GCTGCGATAC ACTTGATAAA GTCTTTATGT ATGCAAAAAA CAAATTTAAA 
AACAAAAGAC TATTGGGAAC ACGTGAAATT TTAAATGAGG AAGATGAAAT ACAGCCAAAT 
GGAAAAATTT TTAAAAAGGT TATTCTGGGG CACTATAATT GGCTTTCCTA TGAAGATGTC 
TTCATCCGAG CCCTTGACTT TGGAAATGGG TTACAAATGT TGGGCCAGAA ACCAAAGGCC 
AACATCGCCA TCTTCTGTGA GACCAGGGCT GAGTGGATGA TCGCTGCACA GGCGTGTTTT 
ATGTATAACT TCCAGCTTGT TACACTGTAT GCTACTCTGG GAGGTCCAGC CATTGTTCAT 
GGACTGAATG AGACAGAGGT GACCAACATC ATTACTAGCA AAGAACTCTT GCAAACAAAG 
CTGAAGGATA TAGTCTCTTT GGTCCCACGT CTGCGGCATA TCATTACTGT TGATGGGAAG 
CCTCCAACCT GGTCTGAGTT CCCCAAAGGT GTCATTGTAC ACACCATGGC TGCAGTGCAG 
GCTCTAGGAG TGAAGGCCAA CGTGGAAAAG AAAGCTCACA GCAAACCACT GCCCTCAGAT 
ATTGCAGTAA TCATGTACAC AAGTGGGTCC ACAGGAATTC CAAAGGGAGT CATGATCTCA 
CACAGCAACA TCATTGCTTC TATAACGGGG ATGGCGAGAA GGATTCCAAG ACTGGGAGAG 
GAAGATGTGT ATATTGGCTA CTTGCCCCTG GCACATGTTC TAGAATTAAG TGCTGAGCTT 
GTGTGTCTTT CTCATGGATG CCGAATCGGC TACTCTTCAC CACAGACATT AGCAGATCAG 
TCTTCAAAAA TAAAAAAAGG AAGCAAAGGA GACACATCCG TGCTGAAGCC AACACTGATG 
GCAGCTGTTC CGGAAATCAT GGATCGGATC TACAAAAATG TCATGAATAA AGTGAATGAA 
ATGAGTGCTT TTCAACGAAA CTTGTTTATT TTGGCATATA ATTATAAGAT GGAACAGATT 
TCAAAAGGGT GTAGTACTCC ACTGTGTGAC CGCTTTGTTT TCCGGAATGT CCGAAGGCTG 
CTGGGTGGAA ATATTCGCCT TTTACTGTGT GGTGGTGCTC CGCTTTCTGC AACAACGCAG 
CGATTCATGA ATATCTGTTT CTGCTGTCCC GTTGGTCAGG GGTATGGACT CACAGAATCT 
ACTGGGGCTG GAACAATTAC AGAAGTGTGG GACTACAATA CCGGCAGAGT GGGAGCACCA 
TTAGTTTGCT GTGAAATCAA ATTAAAGAAC TGGGAGGAAG GTGGCTATTT TAATACTGAC 
AAACCACATC CCAGAGGTGA AATTCTTATT GGTGGCCAAA ATGTGACAAT GGGGTACTAC 
AAAAATGAAG CAAAAACAAA GACAGATTTC TTTGAAGATG AAAATGGACA GCGGTGGCTG 
TGCACTGGAG ATATTGGAGA GTTTGACCCT GACGGCTGTC TGAAGATCAT TGACCGTAAA 
AAGGACCTTG TGAAACTACA GGCAGGAGAG TACGTTTCTC TCGGGAAAGT AGAGGCAGCT 
TTGAAGAACC TCCCACTGAT AGATAACATT TGTGCGTATG CAAACAGCTA CCATTCTTAC 
GTAATTGGGT TTGTTGTGCC AAATCAAAAG GAACTTACAG AGCTAGCTAG AACAAAAGGA 
TTTAAAGGAA CTTGGGAAGA GCTGTGTAAC AGCAGCGAGA TGGAAAATGA GGTCCTTAAA 
GTGCTTTCTG AAGCTGCTAT TTCAGCAAGT CTGGAAAAGT TTGAAATTCC ACTAAAAATA 
CGTTTGAGCC CTGACCCATG GACTCCCGAA ACTGGTCTGG TGACAGATGC CTTCAAGTTG 
AAACGTAAAG AGCTTAAAAC ACACTACCAG GCAGACATTG AGCGGATGTA TGGAAGAAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083093.2
CDS	460..2622
Translation	MNNHVSSTPSTMKLKQTINPILLYFIHFIISLYTILTYIPFYFLCESKQEKPNQIKAKPVSSKPDSAYRSINSVDGLASVLYPGCDTLDKVFMYAKNKFKNKRLLGTREILNEEDEIQPNGKIFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFKGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK

Target ORF information:

RefSeq Version	NM_028817.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028817.3

ORF Insert Sequence:

ATGAATAACC ACGTATCTTC AACACCATCA ACCATGAAGC TAAAACAAAC CATCAACCCC 
ATACTTTTAT ATTTCATACA TTTTATAATA TCACTCTATA CTATTTTAAC ATACATCCCA 
TTTTATTTTT TGTGTGAGTC AAAACAAGAG AAACCAAACC AAATTAAAGC AAAACCTGTC 
AGTTCCAAAC CGGACTCTGC ATACAGATCT ATCAACAGTG TGGATGGCTT GGCTTCAGTG 
CTGTATCCTG GCTGCGATAC ACTTGATAAA GTCTTTATGT ATGCAAAAAA CAAATTTAAA 
AACAAAAGAC TATTGGGAAC ACGTGAAATT TTAAATGAGG AAGATGAAAT ACAGCCAAAT 
GGAAAAATTT TTAAAAAGGT TATTCTGGGG CACTATAATT GGCTTTCCTA TGAAGATGTC 
TTCATCCGAG CCCTTGACTT TGGAAATGGG TTACAAATGT TGGGCCAGAA ACCAAAGGCC 
AACATCGCCA TCTTCTGTGA GACCAGGGCT GAGTGGATGA TCGCTGCACA GGCGTGTTTT 
ATGTATAACT TCCAGCTTGT TACACTGTAT GCTACTCTGG GAGGTCCAGC CATTGTTCAT 
GGACTGAATG AGACAGAGGT GACCAACATC ATTACTAGCA AAGAACTCTT GCAAACAAAG 
CTGAAGGATA TAGTCTCTTT GGTCCCACGT CTGCGGCATA TCATTACTGT TGATGGGAAG 
CCTCCAACCT GGTCTGAGTT CCCCAAAGGT GTCATTGTAC ACACCATGGC TGCAGTGCAG 
GCTCTAGGAG TGAAGGCCAA CGTGGAAAAG AAAGCTCACA GCAAACCACT GCCCTCAGAT 
ATTGCAGTAA TCATGTACAC AAGTGGGTCC ACAGGAATTC CAAAGGGAGT CATGATCTCA 
CACAGCAACA TCATTGCTTC TATAACGGGG ATGGCGAGAA GGATTCCAAG ACTGGGAGAG 
GAAGATGTGT ATATTGGCTA CTTGCCCCTG GCACATGTTC TAGAATTAAG TGCTGAGCTT 
GTGTGTCTTT CTCATGGATG CCGAATCGGC TACTCTTCAC CACAGACATT AGCAGATCAG 
TCTTCAAAAA TAAAAAAAGG AAGCAAAGGA GACACATCCG TGCTGAAGCC AACACTGATG 
GCAGCTGTTC CGGAAATCAT GGATCGGATC TACAAAAATG TCATGAATAA AGTGAATGAA 
ATGAGTGCTT TTCAACGAAA CTTGTTTATT TTGGCATATA ATTATAAGAT GGAACAGATT 
TCAAAAGGGT GTAGTACTCC ACTGTGTGAC CGCTTTGTTT TCCGGAATGT CCGAAGGCTG 
CTGGGTGGAA ATATTCGCCT TTTACTGTGT GGTGGTGCTC CGCTTTCTGC AACAACGCAG 
CGATTCATGA ATATCTGTTT CTGCTGTCCC GTTGGTCAGG GGTATGGACT CACAGAATCT 
ACTGGGGCTG GAACAATTAC AGAAGTGTGG GACTACAATA CCGGCAGAGT GGGAGCACCA 
TTAGTTTGCT GTGAAATCAA ATTAAAGAAC TGGGAGGAAG GTGGCTATTT TAATACTGAC 
AAACCACATC CCAGAGGTGA AATTCTTATT GGTGGCCAAA ATGTGACAAT GGGGTACTAC 
AAAAATGAAG CAAAAACAAA GACAGATTTC TTTGAAGATG AAAATGGACA GCGGTGGCTG 
TGCACTGGAG ATATTGGAGA GTTTGACCCT GACGGCTGTC TGAAGATCAT TGACCGTAAA 
AAGGACCTTG TGAAACTACA GGCAGGAGAG TACGTTTCTC TCGGGAAAGT AGAGGCAGCT 
TTGAAGAACC TCCCACTGAT AGATAACATT TGTGCGTATG CAAACAGCTA CCATTCTTAC 
GTAATTGGGT TTGTTGTGCC AAATCAAAAG GAACTTACAG AGCTAGCTAG AACAAAAGGA 
TTTAAAGGAA CTTGGGAAGA GCTGTGTAAC AGCAGCGAGA TGGAAAATGA GGTCCTTAAA 
GTGCTTTCTG AAGCTGCTAT TTCAGCAAGT CTGGAAAAGT TTGAAATTCC ACTAAAAATA 
CGTTTGAGCC CTGACCCATG GACTCCCGAA ACTGGTCTGG TGACAGATGC CTTCAAGTTG 
AAACGTAAAG AGCTTAAAAC ACACTACCAG GCAGACATTG AGCGGATGTA TGGAAGAAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acsl3 ( NM_001033606.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028778.2 Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu21544
Clone ID Related Accession (Same CDS sequence)	NM_028817.3 , NM_001033606.2
Accession Version	NM_001033606.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	long-chain-fatty-acid--CoA ligase 3 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK161708.1, AK012088.1, AK046000.1 and CK379747.1. On Oct 28, 2008 this sequence version replaced NM_001033606.1. Transcript Variant: This variant (2) lacks an exon in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a). ##Evidence-Data-START## Transcript exon combination :: SRR1660821.182220.1, AK012088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATAACC ACGTATCTTC AACACCATCA ACCATGAAGC TAAAACAAAC CATCAACCCC 
ATACTTTTAT ATTTCATACA TTTTATAATA TCACTCTATA CTATTTTAAC ATACATCCCA 
TTTTATTTTT TGTGTGAGTC AAAACAAGAG AAACCAAACC AAATTAAAGC AAAACCTGTC 
AGTTCCAAAC CGGACTCTGC ATACAGATCT ATCAACAGTG TGGATGGCTT GGCTTCAGTG 
CTGTATCCTG GCTGCGATAC ACTTGATAAA GTCTTTATGT ATGCAAAAAA CAAATTTAAA 
AACAAAAGAC TATTGGGAAC ACGTGAAATT TTAAATGAGG AAGATGAAAT ACAGCCAAAT 
GGAAAAATTT TTAAAAAGGT TATTCTGGGG CACTATAATT GGCTTTCCTA TGAAGATGTC 
TTCATCCGAG CCCTTGACTT TGGAAATGGG TTACAAATGT TGGGCCAGAA ACCAAAGGCC 
AACATCGCCA TCTTCTGTGA GACCAGGGCT GAGTGGATGA TCGCTGCACA GGCGTGTTTT 
ATGTATAACT TCCAGCTTGT TACACTGTAT GCTACTCTGG GAGGTCCAGC CATTGTTCAT 
GGACTGAATG AGACAGAGGT GACCAACATC ATTACTAGCA AAGAACTCTT GCAAACAAAG 
CTGAAGGATA TAGTCTCTTT GGTCCCACGT CTGCGGCATA TCATTACTGT TGATGGGAAG 
CCTCCAACCT GGTCTGAGTT CCCCAAAGGT GTCATTGTAC ACACCATGGC TGCAGTGCAG 
GCTCTAGGAG TGAAGGCCAA CGTGGAAAAG AAAGCTCACA GCAAACCACT GCCCTCAGAT 
ATTGCAGTAA TCATGTACAC AAGTGGGTCC ACAGGAATTC CAAAGGGAGT CATGATCTCA 
CACAGCAACA TCATTGCTTC TATAACGGGG ATGGCGAGAA GGATTCCAAG ACTGGGAGAG 
GAAGATGTGT ATATTGGCTA CTTGCCCCTG GCACATGTTC TAGAATTAAG TGCTGAGCTT 
GTGTGTCTTT CTCATGGATG CCGAATCGGC TACTCTTCAC CACAGACATT AGCAGATCAG 
TCTTCAAAAA TAAAAAAAGG AAGCAAAGGA GACACATCCG TGCTGAAGCC AACACTGATG 
GCAGCTGTTC CGGAAATCAT GGATCGGATC TACAAAAATG TCATGAATAA AGTGAATGAA 
ATGAGTGCTT TTCAACGAAA CTTGTTTATT TTGGCATATA ATTATAAGAT GGAACAGATT 
TCAAAAGGGT GTAGTACTCC ACTGTGTGAC CGCTTTGTTT TCCGGAATGT CCGAAGGCTG 
CTGGGTGGAA ATATTCGCCT TTTACTGTGT GGTGGTGCTC CGCTTTCTGC AACAACGCAG 
CGATTCATGA ATATCTGTTT CTGCTGTCCC GTTGGTCAGG GGTATGGACT CACAGAATCT 
ACTGGGGCTG GAACAATTAC AGAAGTGTGG GACTACAATA CCGGCAGAGT GGGAGCACCA 
TTAGTTTGCT GTGAAATCAA ATTAAAGAAC TGGGAGGAAG GTGGCTATTT TAATACTGAC 
AAACCACATC CCAGAGGTGA AATTCTTATT GGTGGCCAAA ATGTGACAAT GGGGTACTAC 
AAAAATGAAG CAAAAACAAA GACAGATTTC TTTGAAGATG AAAATGGACA GCGGTGGCTG 
TGCACTGGAG ATATTGGAGA GTTTGACCCT GACGGCTGTC TGAAGATCAT TGACCGTAAA 
AAGGACCTTG TGAAACTACA GGCAGGAGAG TACGTTTCTC TCGGGAAAGT AGAGGCAGCT 
TTGAAGAACC TCCCACTGAT AGATAACATT TGTGCGTATG CAAACAGCTA CCATTCTTAC 
GTAATTGGGT TTGTTGTGCC AAATCAAAAG GAACTTACAG AGCTAGCTAG AACAAAAGGA 
TTTAAAGGAA CTTGGGAAGA GCTGTGTAAC AGCAGCGAGA TGGAAAATGA GGTCCTTAAA 
GTGCTTTCTG AAGCTGCTAT TTCAGCAAGT CTGGAAAAGT TTGAAATTCC ACTAAAAATA 
CGTTTGAGCC CTGACCCATG GACTCCCGAA ACTGGTCTGG TGACAGATGC CTTCAAGTTG 
AAACGTAAAG AGCTTAAAAC ACACTACCAG GCAGACATTG AGCGGATGTA TGGAAGAAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028778.2
CDS	320..2482
Translation	MNNHVSSTPSTMKLKQTINPILLYFIHFIISLYTILTYIPFYFLCESKQEKPNQIKAKPVSSKPDSAYRSINSVDGLASVLYPGCDTLDKVFMYAKNKFKNKRLLGTREILNEEDEIQPNGKIFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFKGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK

Target ORF information:

RefSeq Version	NM_001033606.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033606.2

ORF Insert Sequence:

ATGAATAACC ACGTATCTTC AACACCATCA ACCATGAAGC TAAAACAAAC CATCAACCCC 
ATACTTTTAT ATTTCATACA TTTTATAATA TCACTCTATA CTATTTTAAC ATACATCCCA 
TTTTATTTTT TGTGTGAGTC AAAACAAGAG AAACCAAACC AAATTAAAGC AAAACCTGTC 
AGTTCCAAAC CGGACTCTGC ATACAGATCT ATCAACAGTG TGGATGGCTT GGCTTCAGTG 
CTGTATCCTG GCTGCGATAC ACTTGATAAA GTCTTTATGT ATGCAAAAAA CAAATTTAAA 
AACAAAAGAC TATTGGGAAC ACGTGAAATT TTAAATGAGG AAGATGAAAT ACAGCCAAAT 
GGAAAAATTT TTAAAAAGGT TATTCTGGGG CACTATAATT GGCTTTCCTA TGAAGATGTC 
TTCATCCGAG CCCTTGACTT TGGAAATGGG TTACAAATGT TGGGCCAGAA ACCAAAGGCC 
AACATCGCCA TCTTCTGTGA GACCAGGGCT GAGTGGATGA TCGCTGCACA GGCGTGTTTT 
ATGTATAACT TCCAGCTTGT TACACTGTAT GCTACTCTGG GAGGTCCAGC CATTGTTCAT 
GGACTGAATG AGACAGAGGT GACCAACATC ATTACTAGCA AAGAACTCTT GCAAACAAAG 
CTGAAGGATA TAGTCTCTTT GGTCCCACGT CTGCGGCATA TCATTACTGT TGATGGGAAG 
CCTCCAACCT GGTCTGAGTT CCCCAAAGGT GTCATTGTAC ACACCATGGC TGCAGTGCAG 
GCTCTAGGAG TGAAGGCCAA CGTGGAAAAG AAAGCTCACA GCAAACCACT GCCCTCAGAT 
ATTGCAGTAA TCATGTACAC AAGTGGGTCC ACAGGAATTC CAAAGGGAGT CATGATCTCA 
CACAGCAACA TCATTGCTTC TATAACGGGG ATGGCGAGAA GGATTCCAAG ACTGGGAGAG 
GAAGATGTGT ATATTGGCTA CTTGCCCCTG GCACATGTTC TAGAATTAAG TGCTGAGCTT 
GTGTGTCTTT CTCATGGATG CCGAATCGGC TACTCTTCAC CACAGACATT AGCAGATCAG 
TCTTCAAAAA TAAAAAAAGG AAGCAAAGGA GACACATCCG TGCTGAAGCC AACACTGATG 
GCAGCTGTTC CGGAAATCAT GGATCGGATC TACAAAAATG TCATGAATAA AGTGAATGAA 
ATGAGTGCTT TTCAACGAAA CTTGTTTATT TTGGCATATA ATTATAAGAT GGAACAGATT 
TCAAAAGGGT GTAGTACTCC ACTGTGTGAC CGCTTTGTTT TCCGGAATGT CCGAAGGCTG 
CTGGGTGGAA ATATTCGCCT TTTACTGTGT GGTGGTGCTC CGCTTTCTGC AACAACGCAG 
CGATTCATGA ATATCTGTTT CTGCTGTCCC GTTGGTCAGG GGTATGGACT CACAGAATCT 
ACTGGGGCTG GAACAATTAC AGAAGTGTGG GACTACAATA CCGGCAGAGT GGGAGCACCA 
TTAGTTTGCT GTGAAATCAA ATTAAAGAAC TGGGAGGAAG GTGGCTATTT TAATACTGAC 
AAACCACATC CCAGAGGTGA AATTCTTATT GGTGGCCAAA ATGTGACAAT GGGGTACTAC 
AAAAATGAAG CAAAAACAAA GACAGATTTC TTTGAAGATG AAAATGGACA GCGGTGGCTG 
TGCACTGGAG ATATTGGAGA GTTTGACCCT GACGGCTGTC TGAAGATCAT TGACCGTAAA 
AAGGACCTTG TGAAACTACA GGCAGGAGAG TACGTTTCTC TCGGGAAAGT AGAGGCAGCT 
TTGAAGAACC TCCCACTGAT AGATAACATT TGTGCGTATG CAAACAGCTA CCATTCTTAC 
GTAATTGGGT TTGTTGTGCC AAATCAAAAG GAACTTACAG AGCTAGCTAG AACAAAAGGA 
TTTAAAGGAA CTTGGGAAGA GCTGTGTAAC AGCAGCGAGA TGGAAAATGA GGTCCTTAAA 
GTGCTTTCTG AAGCTGCTAT TTCAGCAAGT CTGGAAAAGT TTGAAATTCC ACTAAAAATA 
CGTTTGAGCC CTGACCCATG GACTCCCGAA ACTGGTCTGG TGACAGATGC CTTCAAGTTG 
AAACGTAAAG AGCTTAAAAC ACACTACCAG GCAGACATTG AGCGGATGTA TGGAAGAAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Acsl3 ( NM_001136222.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001129694.1 Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 3, mRNA.

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CloneID	OMu21545
Clone ID Related Accession (Same CDS sequence)	NM_001136222.1
Accession Version	NM_001136222.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565366400000
Organism	Mus musculus(house mouse)
Product	long-chain-fatty-acid--CoA ligase 3 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK161708.1, AK160839.1, AK046000.1 and CK379747.1. Transcript Variant: This variant (3) differs in the 5' UTR and uses a downstream translation initiation codon, compared to variant 1. The resulting isoform (b) is shorter at the N-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AK160839.1, SRR1660817.241662.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGTTGGGCC AGAAACCAAA GGCCAACATC GCCATCTTCT GTGAGACCAG GGCTGAGTGG 
ATGATCGCTG CACAGGCGTG TTTTATGTAT AACTTCCAGC TTGTTACACT GTATGCTACT 
CTGGGAGGTC CAGCCATTGT TCATGGACTG AATGAGACAG AGGTGACCAA CATCATTACT 
AGCAAAGAAC TCTTGCAAAC AAAGCTGAAG GATATAGTCT CTTTGGTCCC ACGTCTGCGG 
CATATCATTA CTGTTGATGG GAAGCCTCCA ACCTGGTCTG AGTTCCCCAA AGGTGTCATT 
GTACACACCA TGGCTGCAGT GCAGGCTCTA GGAGTGAAGG CCAACGTGGA AAAGAAAGCT 
CACAGCAAAC CACTGCCCTC AGATATTGCA GTAATCATGT ACACAAGTGG GTCCACAGGA 
ATTCCAAAGG GAGTCATGAT CTCACACAGC AACATCATTG CTTCTATAAC GGGGATGGCG 
AGAAGGATTC CAAGACTGGG AGAGGAAGAT GTGTATATTG GCTACTTGCC CCTGGCACAT 
GTTCTAGAAT TAAGTGCTGA GCTTGTGTGT CTTTCTCATG GATGCCGAAT CGGCTACTCT 
TCACCACAGA CATTAGCAGA TCAGTCTTCA AAAATAAAAA AAGGAAGCAA AGGAGACACA 
TCCGTGCTGA AGCCAACACT GATGGCAGCT GTTCCGGAAA TCATGGATCG GATCTACAAA 
AATGTCATGA ATAAAGTGAA TGAAATGAGT GCTTTTCAAC GAAACTTGTT TATTTTGGCA 
TATAATTATA AGATGGAACA GATTTCAAAA GGGTGTAGTA CTCCACTGTG TGACCGCTTT 
GTTTTCCGGA ATGTCCGAAG GCTGCTGGGT GGAAATATTC GCCTTTTACT GTGTGGTGGT 
GCTCCGCTTT CTGCAACAAC GCAGCGATTC ATGAATATCT GTTTCTGCTG TCCCGTTGGT 
CAGGGGTATG GACTCACAGA ATCTACTGGG GCTGGAACAA TTACAGAAGT GTGGGACTAC 
AATACCGGCA GAGTGGGAGC ACCATTAGTT TGCTGTGAAA TCAAATTAAA GAACTGGGAG 
GAAGGTGGCT ATTTTAATAC TGACAAACCA CATCCCAGAG GTGAAATTCT TATTGGTGGC 
CAAAATGTGA CAATGGGGTA CTACAAAAAT GAAGCAAAAA CAAAGACAGA TTTCTTTGAA 
GATGAAAATG GACAGCGGTG GCTGTGCACT GGAGATATTG GAGAGTTTGA CCCTGACGGC 
TGTCTGAAGA TCATTGACCG TAAAAAGGAC CTTGTGAAAC TACAGGCAGG AGAGTACGTT 
TCTCTCGGGA AAGTAGAGGC AGCTTTGAAG AACCTCCCAC TGATAGATAA CATTTGTGCG 
TATGCAAACA GCTACCATTC TTACGTAATT GGGTTTGTTG TGCCAAATCA AAAGGAACTT 
ACAGAGCTAG CTAGAACAAA AGGATTTAAA GGAACTTGGG AAGAGCTGTG TAACAGCAGC 
GAGATGGAAA ATGAGGTCCT TAAAGTGCTT TCTGAAGCTG CTATTTCAGC AAGTCTGGAA 
AAGTTTGAAA TTCCACTAAA AATACGTTTG AGCCCTGACC CATGGACTCC CGAAACTGGT 
CTGGTGACAG ATGCCTTCAA GTTGAAACGT AAAGAGCTTA AAACACACTA CCAGGCAGAC 
ATTGAGCGGA TGTATGGAAG AAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129694.1
CDS	358..2064
Translation	MLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFKGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK

Target ORF information:

RefSeq Version	NM_001136222.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus acyl-CoA synthetase long-chain family member 3 (Acsl3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001136222.1

ORF Insert Sequence:

ATGTTGGGCC AGAAACCAAA GGCCAACATC GCCATCTTCT GTGAGACCAG GGCTGAGTGG 
ATGATCGCTG CACAGGCGTG TTTTATGTAT AACTTCCAGC TTGTTACACT GTATGCTACT 
CTGGGAGGTC CAGCCATTGT TCATGGACTG AATGAGACAG AGGTGACCAA CATCATTACT 
AGCAAAGAAC TCTTGCAAAC AAAGCTGAAG GATATAGTCT CTTTGGTCCC ACGTCTGCGG 
CATATCATTA CTGTTGATGG GAAGCCTCCA ACCTGGTCTG AGTTCCCCAA AGGTGTCATT 
GTACACACCA TGGCTGCAGT GCAGGCTCTA GGAGTGAAGG CCAACGTGGA AAAGAAAGCT 
CACAGCAAAC CACTGCCCTC AGATATTGCA GTAATCATGT ACACAAGTGG GTCCACAGGA 
ATTCCAAAGG GAGTCATGAT CTCACACAGC AACATCATTG CTTCTATAAC GGGGATGGCG 
AGAAGGATTC CAAGACTGGG AGAGGAAGAT GTGTATATTG GCTACTTGCC CCTGGCACAT 
GTTCTAGAAT TAAGTGCTGA GCTTGTGTGT CTTTCTCATG GATGCCGAAT CGGCTACTCT 
TCACCACAGA CATTAGCAGA TCAGTCTTCA AAAATAAAAA AAGGAAGCAA AGGAGACACA 
TCCGTGCTGA AGCCAACACT GATGGCAGCT GTTCCGGAAA TCATGGATCG GATCTACAAA 
AATGTCATGA ATAAAGTGAA TGAAATGAGT GCTTTTCAAC GAAACTTGTT TATTTTGGCA 
TATAATTATA AGATGGAACA GATTTCAAAA GGGTGTAGTA CTCCACTGTG TGACCGCTTT 
GTTTTCCGGA ATGTCCGAAG GCTGCTGGGT GGAAATATTC GCCTTTTACT GTGTGGTGGT 
GCTCCGCTTT CTGCAACAAC GCAGCGATTC ATGAATATCT GTTTCTGCTG TCCCGTTGGT 
CAGGGGTATG GACTCACAGA ATCTACTGGG GCTGGAACAA TTACAGAAGT GTGGGACTAC 
AATACCGGCA GAGTGGGAGC ACCATTAGTT TGCTGTGAAA TCAAATTAAA GAACTGGGAG 
GAAGGTGGCT ATTTTAATAC TGACAAACCA CATCCCAGAG GTGAAATTCT TATTGGTGGC 
CAAAATGTGA CAATGGGGTA CTACAAAAAT GAAGCAAAAA CAAAGACAGA TTTCTTTGAA 
GATGAAAATG GACAGCGGTG GCTGTGCACT GGAGATATTG GAGAGTTTGA CCCTGACGGC 
TGTCTGAAGA TCATTGACCG TAAAAAGGAC CTTGTGAAAC TACAGGCAGG AGAGTACGTT 
TCTCTCGGGA AAGTAGAGGC AGCTTTGAAG AACCTCCCAC TGATAGATAA CATTTGTGCG 
TATGCAAACA GCTACCATTC TTACGTAATT GGGTTTGTTG TGCCAAATCA AAAGGAACTT 
ACAGAGCTAG CTAGAACAAA AGGATTTAAA GGAACTTGGG AAGAGCTGTG TAACAGCAGC 
GAGATGGAAA ATGAGGTCCT TAAAGTGCTT TCTGAAGCTG CTATTTCAGC AAGTCTGGAA 
AAGTTTGAAA TTCCACTAAA AATACGTTTG AGCCCTGACC CATGGACTCC CGAAACTGGT 
CTGGTGACAG ATGCCTTCAA GTTGAAACGT AAAGAGCTTA AAACACACTA CCAGGCAGAC 
ATTGAGCGGA TGTATGGAAG AAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Developmental cell39(6)724-739(2016 12)
Menendez-Montes I,Escobar B,Palacios B,Gómez MJ,Izquierdo-Garcia JL,Flores L,Jiménez-Borreguero LJ,Aragones J,Ruiz-Cabello J,Torres M,Martin-Puig S

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Cell reports16(6)1614-1628(2016 08)
Padanad MS,Konstantinidou G,Venkateswaran N,Melegari M,Rindhe S,Mitsche M,Yang C,Batten K,Huffman KE,Liu J,Tang X,Rodriguez-Canales J,Kalhor N,Shay JW,Minna JD,McDonald J,Wistuba II,DeBerardinis RJ,Scaglioni PP

Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity.
The Journal of biological chemistry284(44)30474-83(2009 Oct)
Bu SY,Mashek MT,Mashek DG

Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.
Biochimica et biophysica acta1771(1)75-82(2007 Jan)
de Jong H,Neal AC,Coleman RA,Lewin TM

Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells.
The Journal of biological chemistry279(52)54454-62(2004 Dec)
Pei Z,Fraisl P,Berger J,Jia Z,Forss-Petter S,Watkins PA

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Acsl3 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

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ORF Insert Sequence:

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Target ORF information:

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