IPMK cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	IPMK
Entrez Gene ID	69718
Full Name	inositol polyphosphate multikinase
Synonyms	2410017C19Rik,AA408208,Impk
General protein information	Preferred Names inositol polyphosphate multikinase Names inositol polyphosphate multikinase inositol 1,3,4,6-tetrakisphosphate 5-kinase
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 10 Map Location: 10\|10 B5.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_027184.2	NP_081460.1	inositol polyphosphate multikinase isoform 1
XM_011243555.2	XP_011241857.1	inositol polyphosphate multikinase isoform X1
XM_011243555.1	XP_011241857.1	inositol polyphosphate multikinase isoform X2
NM_001347191.1	NP_001334120.1	inositol polyphosphate multikinase isoform 2
NM_027184.1	NP_081460.1	inositol polyphosphate multikinase

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Ipk2	NP_608535.1
Rattus norvegicus (Norway rat)	Ipmk	NP_599244.1
Arabidopsis thaliana (thale cress)	IPK2BETA	NP_200984.1
Gallus gallus (chicken)	IPMK	XP_004942115.1
Xenopus tropicalis (tropical clawed frog)	ipmk	XP_002937151.2
Oryza sativa (rice)	Os02g0523800	NP_001046986.1
Pan troglodytes (chimpanzee)	IPMK	XP_507801.2
Danio rerio (zebrafish)	ipmkb	NP_001073533.1
Mus musculus (house mouse)	Ipmk	NP_081460.1
Caenorhabditis elegans (roundworm)	CELE_ZK795.1	NP_502402.3
Arabidopsis thaliana (thale cress)	IPK2a	NP_850787.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012099	XP_320429.3
Homo sapiens (human)	IPMK	NP_689416.1
Bos taurus (cattle)	IPMK	NP_001030539.1

Gene Ontology
Bibliography

Related articles in PubMed

Inositol polyphosphate multikinase mediates extinction of fear memory.
Park J, Longo F, Park SJ, Lee S, Bae M, Tyagi R, Han JH, Kim S, Santini E, Klann E, Snyder SH
Proceedings of the National Academy of Sciences of the United States of America116(7)2707-2712(2019 02)

Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.
Fu C, Tyagi R, Chin AC, Rojas T, Li RJ, Guha P, Bernstein IA, Rao F, Xu R, Cha JY, Xu J, Snowman AM, Semenza GL, Snyder SH
Circulation research122(3)457-472(2018 02)

Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6.
Kim E, Beon J, Lee S, Park SJ, Ahn H, Kim MG, Park JE, Kim W, Yuk JM, Kang SJ, Lee SH, Jo EK, Seong RH, Kim S
Science advances3(4)e1602296(2017 Apr)

IPMK and β-catenin mediate PLC-β1-dependent signaling in myogenic differentiation.
Ramazzotti G, Billi AM, Manzoli L, Mazzetti C, Ruggeri A, Erneux C, Kim S, Suh PG, Cocco L, Faenza I
Oncotarget7(51)84118-84127(2016 Dec)

Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.
Ahmed I, Sbodio JI, Harraz MM, Tyagi R, Grima JC, Albacarys LK, Hubbi ME, Xu R, Kim S, Paul BD, Snyder SH
Proceedings of the National Academy of Sciences of the United States of America112(31)9751-6(2015 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IPMK gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IPMK cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu44767	NM_001347191.1 Latest version!	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu70463	XM_011243555.2 Latest version!	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu18524	NM_027184.2 Latest version!	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
View Old Accession Versions >>
OMu70463	XM_011243555.1	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu18524	NM_027184.1	Mus musculus inositol polyphosphate multikinase (Ipmk), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IPMK ( NM_027184.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_081460.1 Mus musculus inositol polyphosphate multikinase (Ipmk), mRNA.

Price & Availability↑

CloneID	OMu18524
Clone ID Related Accession (Same CDS sequence)	NM_027184.2 , NM_027184.1
Accession Version	NM_027184.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1423843200000
Organism	Mus musculus(House mouse)
Product	inositol polyphosphate multikinase
Comment

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGATGTGTAC CTAAAACTGG AAGATGTGAC TCATAAGTTT 
AACAAACCCT GTATAATGGA CGTGAAGATT GGGCGGAAGA GCTACGACCC CTTTGCGTCA 
TCAGAGAAGA TTCAGCAGCA GGTCAGCAAG TACCCTCTGA TGGAGGAGAT CGGGTTCCTG 
GTGCTCGGCA TGAGGGTTTA TCATCTTCAC TCTGACAGCT ACGAGACACA AAACCAGCAC 
TATGGAAGAG GCCTAACGAA AGAGACCCTG AAGGAAGGCG TCTCCAAGTT TTTCCACAAT 
GGCTTCTGTT TAAGAAAAGA TGCGATTGCC GCCAGTATTC AGAAGGTAGA GAAGATTCTC 
CAGTGGTTTG AAAATCAGAA GCAGCTTAAC TTTTACGCAA GTTCTTTACT GTTTGTTTAT 
GAAGGTTCAT CTCAGCCAGC TACTACAAAA GCAAACGATA GAACTTTGGC GGGGAGGTTT 
CTCTCCAAAG GACCCCTGAC GGATGCGGAC GGCCTGGAGT GCAATAACAA CTTCCACCTG 
TTCGGCGCCC CGCCCAACGG GATGTCGGTG GGCAAGAGCT TATCGAAGGC GTACTCGAGG 
CACAGAAAGC TGTATGCAAA AAAGCACCAG AGTCAGACTT CCCTGAAAGT CGAAACGCTG 
GAGCAAGACA ACGGGTGGAG AAGCATGTCC CAGGAACACT TAAACGGAAA CGTGCTTGCC 
CAACTGGAAA AGGTGTTCTA CCACCTTCCC GCGGGTCGTC CGGAGATCCC GGAAGCGGAA 
GTACGGATGA TAGACTTTGC TCACGTGTTC CCTAGCAACA CAGTCGATGA GGGGTATGTT 
TACGGTCTGA AGCATCTAAT TGCCGTGCTT CGGAGTATTT TAGACAGTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081460.1
Translation	MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPTAPNDVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEGVSKFFHNGFCLRKDAIAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSSQPATTKANDRTLAGRFLSKGPLTDADGLECNNNFHLFGAPPNGMSVGKSLSKAYSRHRKLYAKKHQSQTSLKVETLEQDNGWRSMSQEHLNGNVLAQLEKVFYHLPAGRPEIPEAEVRMIDFAHVFPSNTVDEGYVYGLKHLIAVLRSILDS

Target ORF information:

RefSeq Version	NM_027184.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus inositol polyphosphate multikinase (Ipmk), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027184.1

ORF Insert Sequence:

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGATGTGTAC CTAAAACTGG AAGATGTGAC TCATAAGTTT 
AACAAACCCT GTATAATGGA CGTGAAGATT GGGCGGAAGA GCTACGACCC CTTTGCGTCA 
TCAGAGAAGA TTCAGCAGCA GGTCAGCAAG TACCCTCTGA TGGAGGAGAT CGGGTTCCTG 
GTGCTCGGCA TGAGGGTTTA TCATCTTCAC TCTGACAGCT ACGAGACACA AAACCAGCAC 
TATGGAAGAG GCCTAACGAA AGAGACCCTG AAGGAAGGCG TCTCCAAGTT TTTCCACAAT 
GGCTTCTGTT TAAGAAAAGA TGCGATTGCC GCCAGTATTC AGAAGGTAGA GAAGATTCTC 
CAGTGGTTTG AAAATCAGAA GCAGCTTAAC TTTTACGCAA GTTCTTTACT GTTTGTTTAT 
GAAGGTTCAT CTCAGCCAGC TACTACAAAA GCAAACGATA GAACTTTGGC GGGGAGGTTT 
CTCTCCAAAG GACCCCTGAC GGATGCGGAC GGCCTGGAGT GCAATAACAA CTTCCACCTG 
TTCGGCGCCC CGCCCAACGG GATGTCGGTG GGCAAGAGCT TATCGAAGGC GTACTCGAGG 
CACAGAAAGC TGTATGCAAA AAAGCACCAG AGTCAGACTT CCCTGAAAGT CGAAACGCTG 
GAGCAAGACA ACGGGTGGAG AAGCATGTCC CAGGAACACT TAAACGGAAA CGTGCTTGCC 
CAACTGGAAA AGGTGTTCTA CCACCTTCCC GCGGGTCGTC CGGAGATCCC GGAAGCGGAA 
GTACGGATGA TAGACTTTGC TCACGTGTTC CCTAGCAACA CAGTCGATGA GGGGTATGTT 
TACGGTCTGA AGCATCTAAT TGCCGTGCTT CGGAGTATTT TAGACAGTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPMK ( NM_001347191.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_001334120.1 Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu44767
Clone ID Related Accession (Same CDS sequence)	NM_001347191.1
Accession Version	NM_001347191.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573401600000
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate multikinase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC156270.5, BC052463.1 and BI134125.1. On Nov 18, 2016 this sequence version replaced XM_006514056.3. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) has the same N- and C-termini, but is one aa longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AI552241.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGCAGATGTG TACCTAAAAC TGGAAGATGT GACTCATAAG 
TTTAACAAAC CCTGTATAAT GGACGTGAAG ATTGGGCGGA AGAGCTACGA CCCCTTTGCG 
TCATCAGAGA AGATTCAGCA GCAGGTCAGC AAGTACCCTC TGATGGAGGA GATCGGGTTC 
CTGGTGCTCG GCATGAGGGT TTATCATCTT CACTCTGACA GCTACGAGAC ACAAAACCAG 
CACTATGGAA GAGGCCTAAC GAAAGAGACC CTGAAGGAAG GCGTCTCCAA GTTTTTCCAC 
AATGGCTTCT GTTTAAGAAA AGATGCGATT GCCGCCAGTA TTCAGAAGGT AGAGAAGATT 
CTCCAGTGGT TTGAAAATCA GAAGCAGCTT AACTTTTACG CAAGTTCTTT ACTGTTTGTT 
TATGAAGGTT CATCTCAGCC AGCTACTACA AAAGCAAACG ATAGAACTTT GGCGGGGAGG 
TTTCTCTCCA AAGGACCCCT GACGGATGCG GACGGCCTGG AGTGCAATAA CAACTTCCAC 
CTGTTCGGCG CCCCGCCCAA CGGGATGTCG GTGGGCAAGA GCTTATCGAA GGCGTACTCG 
AGGCACAGAA AGCTGTATGC AAAAAAGCAC CAGAGTCAGA CTTCCCTGAA AGTCGAAACG 
CTGGAGCAAG ACAACGGGTG GAGAAGCATG TCCCAGGAAC ACTTAAACGG AAACGTGCTT 
GCCCAACTGG AAAAGGTGTT CTACCACCTT CCCGCGGGTC GTCCGGAGAT CCCGGAAGCG 
GAAGTACGGA TGATAGACTT TGCTCACGTG TTCCCTAGCA ACACAGTCGA TGAGGGGTAT 
GTTTACGGTC TGAAGCATCT AATTGCCGTG CTTCGGAGTA TTTTAGACAG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334120.1
CDS	189..1382
Translation	MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPTAPNADVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEGVSKFFHNGFCLRKDAIAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSSQPATTKANDRTLAGRFLSKGPLTDADGLECNNNFHLFGAPPNGMSVGKSLSKAYSRHRKLYAKKHQSQTSLKVETLEQDNGWRSMSQEHLNGNVLAQLEKVFYHLPAGRPEIPEAEVRMIDFAHVFPSNTVDEGYVYGLKHLIAVLRSILDS

Target ORF information:

RefSeq Version	NM_001347191.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347191.1

ORF Insert Sequence:

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGCAGATGTG TACCTAAAAC TGGAAGATGT GACTCATAAG 
TTTAACAAAC CCTGTATAAT GGACGTGAAG ATTGGGCGGA AGAGCTACGA CCCCTTTGCG 
TCATCAGAGA AGATTCAGCA GCAGGTCAGC AAGTACCCTC TGATGGAGGA GATCGGGTTC 
CTGGTGCTCG GCATGAGGGT TTATCATCTT CACTCTGACA GCTACGAGAC ACAAAACCAG 
CACTATGGAA GAGGCCTAAC GAAAGAGACC CTGAAGGAAG GCGTCTCCAA GTTTTTCCAC 
AATGGCTTCT GTTTAAGAAA AGATGCGATT GCCGCCAGTA TTCAGAAGGT AGAGAAGATT 
CTCCAGTGGT TTGAAAATCA GAAGCAGCTT AACTTTTACG CAAGTTCTTT ACTGTTTGTT 
TATGAAGGTT CATCTCAGCC AGCTACTACA AAAGCAAACG ATAGAACTTT GGCGGGGAGG 
TTTCTCTCCA AAGGACCCCT GACGGATGCG GACGGCCTGG AGTGCAATAA CAACTTCCAC 
CTGTTCGGCG CCCCGCCCAA CGGGATGTCG GTGGGCAAGA GCTTATCGAA GGCGTACTCG 
AGGCACAGAA AGCTGTATGC AAAAAAGCAC CAGAGTCAGA CTTCCCTGAA AGTCGAAACG 
CTGGAGCAAG ACAACGGGTG GAGAAGCATG TCCCAGGAAC ACTTAAACGG AAACGTGCTT 
GCCCAACTGG AAAAGGTGTT CTACCACCTT CCCGCGGGTC GTCCGGAGAT CCCGGAAGCG 
GAAGTACGGA TGATAGACTT TGCTCACGTG TTCCCTAGCA ACACAGTCGA TGAGGGGTAT 
GTTTACGGTC TGAAGCATCT AATTGCCGTG CTTCGGAGTA TTTTAGACAG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPMK ( XM_011243555.2 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_011241857.1 Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70463
Clone ID Related Accession (Same CDS sequence)	XM_011243555.2 , XM_011243555.1
Accession Version	XM_011243555.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate multikinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011243555.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGCAGATGTG TACCTAAAAC TGGAAGATGT GACTCATAAG 
TTTAACAAAC CCTGTATAAT GGACGTGAAG ATTGGGCGGA AGAGCTACGA CCCCTTTGCG 
TCATCAGAGA AGATTCAGCA GCAGGTCAGC AAGTACCCTC TGATGGAGGA GATCGGGTTC 
CTGGTGCTCG GCATGAGGGT TTATCATCTT CACTCTGACA GCTACGAGAC ACAAAACCAG 
CACTATGGAA GAGGCCTAAC GAAAGAGACC CTGAAGGAAG TTGCTGGCCC ACTTGCTTCC 
TACTGCTGCG ATAAATCCCC GAGACAACCC ACCATGAAGG AGCTTTTGTT CGGTTCAGAT 
TCAGGTGTAT CTGGTAGCTC CTTTGCTTTG GACACAACAA GGGAGCAGCC ATGGGGAGTA 
AATACGTCCT GTTCCTGGGT GACCCGGACG CAGGGAGGCC CAGGCCCTTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011241857.1
CDS	209..982
Translation	MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPTAPNADVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEVAGPLASYCCDKSPRQPTMKELLFGSDSGVSGSSFALDTTREQPWGVNTSCSWVTRTQGGPGPS

Target ORF information:

RefSeq Version	XM_011243555.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011243555.2

ORF Insert Sequence:

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGCAGATGTG TACCTAAAAC TGGAAGATGT GACTCATAAG 
TTTAACAAAC CCTGTATAAT GGACGTGAAG ATTGGGCGGA AGAGCTACGA CCCCTTTGCG 
TCATCAGAGA AGATTCAGCA GCAGGTCAGC AAGTACCCTC TGATGGAGGA GATCGGGTTC 
CTGGTGCTCG GCATGAGGGT TTATCATCTT CACTCTGACA GCTACGAGAC ACAAAACCAG 
CACTATGGAA GAGGCCTAAC GAAAGAGACC CTGAAGGAAG TTGCTGGCCC ACTTGCTTCC 
TACTGCTGCG ATAAATCCCC GAGACAACCC ACCATGAAGG AGCTTTTGTT CGGTTCAGAT 
TCAGGTGTAT CTGGTAGCTC CTTTGCTTTG GACACAACAA GGGAGCAGCC ATGGGGAGTA 
AATACGTCCT GTTCCTGGGT GACCCGGACG CAGGGAGGCC CAGGCCCTTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPMK ( XM_011243555.1 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_011241857.1 Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu70463
Clone ID Related Accession (Same CDS sequence)	XM_011243555.2 , XM_011243555.1
Accession Version	XM_011243555.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate multikinase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGCAGATGTG TACCTAAAAC TGGAAGATGT GACTCATAAG 
TTTAACAAAC CCTGTATAAT GGACGTGAAG ATTGGGCGGA AGAGCTACGA CCCCTTTGCG 
TCATCAGAGA AGATTCAGCA GCAGGTCAGC AAGTACCCTC TGATGGAGGA GATCGGGTTC 
CTGGTGCTCG GCATGAGGGT TTATCATCTT CACTCTGACA GCTACGAGAC ACAAAACCAG 
CACTATGGAA GAGGCCTAAC GAAAGAGACC CTGAAGGAAG TTGCTGGCCC ACTTGCTTCC 
TACTGCTGCG ATAAATCCCC GAGACAACCC ACCATGAAGG AGCTTTTGTT CGGTTCAGAT 
TCAGGTGTAT CTGGTAGCTC CTTTGCTTTG GACACAACAA GGGAGCAGCC ATGGGGAGTA 
AATACGTCCT GTTCCTGGGT GACCCGGACG CAGGGAGGCC CAGGCCCTTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011241857.1
CDS	185..958
Translation	MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPTAPNADVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEVAGPLASYCCDKSPRQPTMKELLFGSDSGVSGSSFALDTTREQPWGVNTSCSWVTRTQGGPGPS

Target ORF information:

RefSeq Version	XM_011243555.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011243555.1

ORF Insert Sequence:

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGCAGATGTG TACCTAAAAC TGGAAGATGT GACTCATAAG 
TTTAACAAAC CCTGTATAAT GGACGTGAAG ATTGGGCGGA AGAGCTACGA CCCCTTTGCG 
TCATCAGAGA AGATTCAGCA GCAGGTCAGC AAGTACCCTC TGATGGAGGA GATCGGGTTC 
CTGGTGCTCG GCATGAGGGT TTATCATCTT CACTCTGACA GCTACGAGAC ACAAAACCAG 
CACTATGGAA GAGGCCTAAC GAAAGAGACC CTGAAGGAAG TTGCTGGCCC ACTTGCTTCC 
TACTGCTGCG ATAAATCCCC GAGACAACCC ACCATGAAGG AGCTTTTGTT CGGTTCAGAT 
TCAGGTGTAT CTGGTAGCTC CTTTGCTTTG GACACAACAA GGGAGCAGCC ATGGGGAGTA 
AATACGTCCT GTTCCTGGGT GACCCGGACG CAGGGAGGCC CAGGCCCTTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPMK ( NM_027184.2 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_081460.1 Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant 1, mRNA.

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CloneID	OMu18524
Clone ID Related Accession (Same CDS sequence)	NM_027184.2 , NM_027184.1
Accession Version	NM_027184.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573401600000
Organism	Mus musculus(house mouse)
Product	inositol polyphosphate multikinase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC156270.5 and BC052463.1. On Nov 18, 2016 this sequence version replaced NM_027184.1. Transcript Variant: This variant (1) encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052463.1, AK036084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGATGTGTAC CTAAAACTGG AAGATGTGAC TCATAAGTTT 
AACAAACCCT GTATAATGGA CGTGAAGATT GGGCGGAAGA GCTACGACCC CTTTGCGTCA 
TCAGAGAAGA TTCAGCAGCA GGTCAGCAAG TACCCTCTGA TGGAGGAGAT CGGGTTCCTG 
GTGCTCGGCA TGAGGGTTTA TCATCTTCAC TCTGACAGCT ACGAGACACA AAACCAGCAC 
TATGGAAGAG GCCTAACGAA AGAGACCCTG AAGGAAGGCG TCTCCAAGTT TTTCCACAAT 
GGCTTCTGTT TAAGAAAAGA TGCGATTGCC GCCAGTATTC AGAAGGTAGA GAAGATTCTC 
CAGTGGTTTG AAAATCAGAA GCAGCTTAAC TTTTACGCAA GTTCTTTACT GTTTGTTTAT 
GAAGGTTCAT CTCAGCCAGC TACTACAAAA GCAAACGATA GAACTTTGGC GGGGAGGTTT 
CTCTCCAAAG GACCCCTGAC GGATGCGGAC GGCCTGGAGT GCAATAACAA CTTCCACCTG 
TTCGGCGCCC CGCCCAACGG GATGTCGGTG GGCAAGAGCT TATCGAAGGC GTACTCGAGG 
CACAGAAAGC TGTATGCAAA AAAGCACCAG AGTCAGACTT CCCTGAAAGT CGAAACGCTG 
GAGCAAGACA ACGGGTGGAG AAGCATGTCC CAGGAACACT TAAACGGAAA CGTGCTTGCC 
CAACTGGAAA AGGTGTTCTA CCACCTTCCC GCGGGTCGTC CGGAGATCCC GGAAGCGGAA 
GTACGGATGA TAGACTTTGC TCACGTGTTC CCTAGCAACA CAGTCGATGA GGGGTATGTT 
TACGGTCTGA AGCATCTAAT TGCCGTGCTT CGGAGTATTT TAGACAGTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081460.1
CDS	189..1379
Translation	MAAEPPALRLRPPGSTGDSPPVPRLLGGCVPLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYTMVYAADCADAVLLELRKHLPKYYGVWSPPTAPNDVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEGVSKFFHNGFCLRKDAIAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSSQPATTKANDRTLAGRFLSKGPLTDADGLECNNNFHLFGAPPNGMSVGKSLSKAYSRHRKLYAKKHQSQTSLKVETLEQDNGWRSMSQEHLNGNVLAQLEKVFYHLPAGRPEIPEAEVRMIDFAHVFPSNTVDEGYVYGLKHLIAVLRSILDS

Target ORF information:

RefSeq Version	NM_027184.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027184.2

ORF Insert Sequence:

ATGGCCGCCG AGCCCCCAGC GCTGCGCCTG CGGCCGCCGG GAAGCACCGG AGACAGCCCG 
CCGGTGCCGC GCCTGCTCGG AGGCTGCGTG CCGCTGTCGC ATCAGGTGGC TGGCCACATG 
TACGGCAAGG ACAAAGTGGG CATACTCCAG CACCCAGATG GTACAGTTCT GAAACAGCTA 
CAGCCACCGC CACGGGGCCC AAGAGAGCTG GAATTTTATA CCATGGTTTA CGCTGCTGAC 
TGTGCCGATG CTGTTCTCCT GGAGCTGCGA AAACACCTGC CCAAATACTA CGGCGTCTGG 
TCCCCTCCCA CCGCACCAAA CGATGTGTAC CTAAAACTGG AAGATGTGAC TCATAAGTTT 
AACAAACCCT GTATAATGGA CGTGAAGATT GGGCGGAAGA GCTACGACCC CTTTGCGTCA 
TCAGAGAAGA TTCAGCAGCA GGTCAGCAAG TACCCTCTGA TGGAGGAGAT CGGGTTCCTG 
GTGCTCGGCA TGAGGGTTTA TCATCTTCAC TCTGACAGCT ACGAGACACA AAACCAGCAC 
TATGGAAGAG GCCTAACGAA AGAGACCCTG AAGGAAGGCG TCTCCAAGTT TTTCCACAAT 
GGCTTCTGTT TAAGAAAAGA TGCGATTGCC GCCAGTATTC AGAAGGTAGA GAAGATTCTC 
CAGTGGTTTG AAAATCAGAA GCAGCTTAAC TTTTACGCAA GTTCTTTACT GTTTGTTTAT 
GAAGGTTCAT CTCAGCCAGC TACTACAAAA GCAAACGATA GAACTTTGGC GGGGAGGTTT 
CTCTCCAAAG GACCCCTGAC GGATGCGGAC GGCCTGGAGT GCAATAACAA CTTCCACCTG 
TTCGGCGCCC CGCCCAACGG GATGTCGGTG GGCAAGAGCT TATCGAAGGC GTACTCGAGG 
CACAGAAAGC TGTATGCAAA AAAGCACCAG AGTCAGACTT CCCTGAAAGT CGAAACGCTG 
GAGCAAGACA ACGGGTGGAG AAGCATGTCC CAGGAACACT TAAACGGAAA CGTGCTTGCC 
CAACTGGAAA AGGTGTTCTA CCACCTTCCC GCGGGTCGTC CGGAGATCCC GGAAGCGGAA 
GTACGGATGA TAGACTTTGC TCACGTGTTC CCTAGCAACA CAGTCGATGA GGGGTATGTT 
TACGGTCTGA AGCATCTAAT TGCCGTGCTT CGGAGTATTT TAGACAGTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Inositol polyphosphate multikinase mediates extinction of fear memory.
Proceedings of the National Academy of Sciences of the United States of America116(7)2707-2712(2019 02)
Park J,Longo F,Park SJ,Lee S,Bae M,Tyagi R,Han JH,Kim S,Santini E,Klann E,Snyder SH

Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.
Circulation research122(3)457-472(2018 02)
Fu C,Tyagi R,Chin AC,Rojas T,Li RJ,Guha P,Bernstein IA,Rao F,Xu R,Cha JY,Xu J,Snowman AM,Semenza GL,Snyder SH

Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6.
Science advances3(4)e1602296(2017 Apr)
Kim E,Beon J,Lee S,Park SJ,Ahn H,Kim MG,Park JE,Kim W,Yuk JM,Kang SJ,Lee SH,Jo EK,Seong RH,Kim S

IPMK and β-catenin mediate PLC-β1-dependent signaling in myogenic differentiation.
Oncotarget7(51)84118-84127(2016 Dec)
Ramazzotti G,Billi AM,Manzoli L,Mazzetti C,Ruggeri A,Erneux C,Kim S,Suh PG,Cocco L,Faenza I

Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.
Proceedings of the National Academy of Sciences of the United States of America112(31)9751-6(2015 Aug)
Ahmed I,Sbodio JI,Harraz MM,Tyagi R,Grima JC,Albacarys LK,Hubbi ME,Xu R,Kim S,Paul BD,Snyder SH

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IPMK cDNA ORF clone, Mus musculus(House mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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