Idh3a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Idh3a
Entrez Gene ID	67834
Full Name	isocitrate dehydrogenase 3 (NAD+) alpha
Synonyms	1110003P10Rik,1500012E04Rik,AA407078,AI316514
General protein information	Preferred Names isocitrate dehydrogenase 3 (NAD+) alpha Names isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial NAD(+)-specific ICDH subunit alpha isocitric dehydrogenase subunit alpha
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 A5.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_029573.2	NP_083849.1	isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor

Pathways from BioSystems

Homologies

Kluyveromyces lactis	KLLA0E03125g	XP_454086.1
Homo sapiens (human)	IDH3A	NP_005521.1
Bos taurus (cattle)	IDH3A	NP_777069.1
Danio rerio (zebrafish)	idh3a	NP_957245.2
Drosophila melanogaster (fruit fly)	l(1)G0156	NP_001259705.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002728	XP_312198.5
Gallus gallus (chicken)	IDH3A	NP_001005808.1
Caenorhabditis elegans (roundworm)	idha-1	NP_492330.2
Arabidopsis thaliana (thale cress)	IDH-V	NP_568113.1
Schizosaccharomyces pombe (fission yeast)	idh2	NP_595203.2
Magnaporthe oryzae (rice blast fungus)	MGG_01712	XP_003714707.1
Canis lupus familiaris (dog)	IDH3A	XP_536213.2
Arabidopsis thaliana (thale cress)	IDH-VI	NP_850549.1
Neurospora crassa	NCU07697	XP_962283.1
Pan troglodytes (chimpanzee)	IDH3A	XP_510524.3
Macaca mulatta (Rhesus monkey)	IDH3A	XP_001106839.2
Mus musculus (house mouse)	Idh3a	NP_083849.1
Rattus norvegicus (Norway rat)	Idh3a	NP_446090.1
Saccharomyces cerevisiae (baker's yeast)	IDH2	NP_014779.1
Oryza sativa (rice)	Os01g0276100	NP_001042725.1
Xenopus tropicalis (tropical clawed frog)	idh3a	NP_989352.1
Eremothecium gossypii	AGOS_AFR137C	NP_985684.1

Gene Ontology
Bibliography

Related articles in PubMed

Mouse
Findlay AS, Carter RN, Starbuck B, McKie L, Nováková K, Budd PS, Keighren MA, Marsh JA, Cross SH, Simon MM, Potter PK, Morton NM, Jackson IJ
Disease models & mechanisms11(12)(2018 12)

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A
Developmental cell40(4)331-341.e4(2017 02)

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Bowman CE, Zhao L, Hartung T, Wolfgang MJ
Molecular and cellular biology36(15)2089-104(2016 08)

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Potter PK, Bowl MR, Jeyarajan P, Wisby L, Blease A, Goldsworthy ME, Simon MM, Greenaway S, Michel V, Barnard A, Aguilar C, Agnew T, Banks G, Blake A, Chessum L, Dorning J, Falcone S, Goosey L, Harris S, Haynes A, Heise I, Hillier R, Hough T, Hoslin A, Hutchison M, King R, Kumar S, Lad HV, Law G, MacLaren RE, Morse S, Nicol T, Parker A, Pickford K, Sethi S, Starbuck B, Stelma F, Cheeseman M, Cross SH, Foster RG, Jackson IJ, Peirson SN, Thakker RV, Vincent T, Scudamore C, Wells S, El-Amraoui A, Petit C, Acevedo-Arozena A, Nolan PM, Cox R, Mallon AM, Brown SD
Nature communications712444(2016 08)

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ
PLoS genetics5(6)e1000511(2009 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Idh3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Idh3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14654	NM_029573.2 Latest version!	Mus musculus isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Idh3a ( NM_029573.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_083849.1 Mus musculus isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a), mRNA.

Price & Availability↑

CloneID	OMu14654
Clone ID Related Accession (Same CDS sequence)	NM_029573.2
Accession Version	NM_029573.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC049956.1. On Jun 10, 2003 this sequence version replaced NM_029573.1. ##Evidence-Data-START## Transcript exon combination :: BC049956.1, AK158646.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCCGGGT CCGCGTGGGT GTCCAAGGTC TCTCGGCTGC TGGGTGCATT CCACAACACA 
AAACAGGTGA CAAGAGGTTT TGCTGGTGGT GTTCAGACAG TAACTTTAAT TCCTGGAGAT 
GGAATTGGCC CAGAAATTTC AGCCTCAGTC ATGAAGATTT TTGATGCTGC CAAAGCACCT 
ATTCAGTGGG AGGAGCGCAA TGTCACAGCA ATTCAAGGAC CAGGAGGAAA GTGGATGATC 
CCTCCAGAAG CCAAGGAGTC CATGGATAAG AACAAGATGG GCTTGAAAGG CCCACTAAAG 
ACCCCAATAG CCGCTGGCCA TCCATCTATG AATCTGTTGC TTCGTAAGAC ATTTGACCTT 
TATGCCAATG TCCGGCCATG TGTCTCAATT GAAGGTTATA AAACCCCTTA CACGGATGTA 
AATATCGTCA CCATCCGAGA GAACACGGAA GGAGAATACA GTGGAATTGA GCATGTGATC 
GTTGATGGGG TTGTGCAGAG CATCAAGCTC ATCACCGAAG AAGCAAGCAA GCGCATTGCA 
GAGTTTGCCT TCGAGTACGC TCGGAACAAC CACCGGAGCA ACGTCACAGC TGTGCACAAA 
GCTAACATCA TGAGGATGTC AGATGGGCTC TTTCTGCAAA AATGCAGGGA AGTTGCGGAG 
AACTGTAAAG ACATTAAATT TAACGAGATG TACCTTGATA CTGTATGTTT AAATATGGTA 
CAAGACCCAT CCCAGTTTGA TGTTCTTGTC ATGCCAAATT TATACGGAGA CATCCTTAGT 
GATCTGTGTG CAGGACTGAT TGGAGGTCTT GGGGTGACTC CAAGTGGCAA TATTGGAGCC 
AACGGTGTTG CCATCTTTGA ATCGGTTCAT GGAACAGCCC CGGACATTGC AGGCAAGGAC 
ATGGCCAACC CCACGGCCCT CCTGCTTAGT GCTGTGATGA TGCTTCGCCA CATGGGACTT 
TTTGACCATG CAGCAAAAAT CGAGGCTGCA TGTTTTGCTA CAATTAAGGA TGGAAAGAGC 
TTAACAAAAG ATCTGGGAGG CAACGCGAAG TGCTCTGACT TCACAGAAGA AATCTGTCGT 
AGAGTCAAAG ACTTAGATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_083849.1
CDS	7..1107
Translation	MAGSAWVSKVSRLLGAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD

Target ORF information:

RefSeq Version	NM_029573.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029573.2

ORF Insert Sequence:

ATGGCCGGGT CCGCGTGGGT GTCCAAGGTC TCTCGGCTGC TGGGTGCATT CCACAACACA 
AAACAGGTGA CAAGAGGTTT TGCTGGTGGT GTTCAGACAG TAACTTTAAT TCCTGGAGAT 
GGAATTGGCC CAGAAATTTC AGCCTCAGTC ATGAAGATTT TTGATGCTGC CAAAGCACCT 
ATTCAGTGGG AGGAGCGCAA TGTCACAGCA ATTCAAGGAC CAGGAGGAAA GTGGATGATC 
CCTCCAGAAG CCAAGGAGTC CATGGATAAG AACAAGATGG GCTTGAAAGG CCCACTAAAG 
ACCCCAATAG CCGCTGGCCA TCCATCTATG AATCTGTTGC TTCGTAAGAC ATTTGACCTT 
TATGCCAATG TCCGGCCATG TGTCTCAATT GAAGGTTATA AAACCCCTTA CACGGATGTA 
AATATCGTCA CCATCCGAGA GAACACGGAA GGAGAATACA GTGGAATTGA GCATGTGATC 
GTTGATGGGG TTGTGCAGAG CATCAAGCTC ATCACCGAAG AAGCAAGCAA GCGCATTGCA 
GAGTTTGCCT TCGAGTACGC TCGGAACAAC CACCGGAGCA ACGTCACAGC TGTGCACAAA 
GCTAACATCA TGAGGATGTC AGATGGGCTC TTTCTGCAAA AATGCAGGGA AGTTGCGGAG 
AACTGTAAAG ACATTAAATT TAACGAGATG TACCTTGATA CTGTATGTTT AAATATGGTA 
CAAGACCCAT CCCAGTTTGA TGTTCTTGTC ATGCCAAATT TATACGGAGA CATCCTTAGT 
GATCTGTGTG CAGGACTGAT TGGAGGTCTT GGGGTGACTC CAAGTGGCAA TATTGGAGCC 
AACGGTGTTG CCATCTTTGA ATCGGTTCAT GGAACAGCCC CGGACATTGC AGGCAAGGAC 
ATGGCCAACC CCACGGCCCT CCTGCTTAGT GCTGTGATGA TGCTTCGCCA CATGGGACTT 
TTTGACCATG CAGCAAAAAT CGAGGCTGCA TGTTTTGCTA CAATTAAGGA TGGAAAGAGC 
TTAACAAAAG ATCTGGGAGG CAACGCGAAG TGCTCTGACT TCACAGAAGA AATCTGTCGT 
AGAGTCAAAG ACTTAGATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mouse
Disease models & mechanisms11(12)(2018 12)
Findlay AS,Carter RN,Starbuck B,McKie L,Nováková K,Budd PS,Keighren MA,Marsh JA,Cross SH,Simon MM,Potter PK,Morton NM,Jackson IJ

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Developmental cell40(4)331-341.e4(2017 02)
Bulusu V,Prior N,Snaebjornsson MT,Kuehne A,Sonnen KF,Kress J,Stein F,Schultz C,Sauer U,Aulehla A

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Molecular and cellular biology36(15)2089-104(2016 08)
Bowman CE,Zhao L,Hartung T,Wolfgang MJ

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Nature communications712444(2016 08)
Potter PK,Bowl MR,Jeyarajan P,Wisby L,Blease A,Goldsworthy ME,Simon MM,Greenaway S,Michel V,Barnard A,Aguilar C,Agnew T,Banks G,Blake A,Chessum L,Dorning J,Falcone S,Goosey L,Harris S,Haynes A,Heise I,Hillier R,Hough T,Hoslin A,Hutchison M,King R,Kumar S,Lad HV,Law G,MacLaren RE,Morse S,Nicol T,Parker A,Pickford K,Sethi S,Starbuck B,Stelma F,Cheeseman M,Cross SH,Foster RG,Jackson IJ,Peirson SN,Thakker RV,Vincent T,Scudamore C,Wells S,El-Amraoui A,Petit C,Acevedo-Arozena A,Nolan PM,Cox R,Mallon AM,Brown SD

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
PLoS genetics5(6)e1000511(2009 Jun)
Sansom SN,Griffiths DS,Faedo A,Kleinjan DJ,Ruan Y,Smith J,van Heyningen V,Rubenstein JL,Livesey FJ

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Idh3a cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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