Pes1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pes1
Entrez Gene ID	64934
Full Name	pescadillo ribosomal biogenesis factor 1
General protein information	Preferred Names pescadillo ribosomal biogenesis factor 1 Names pescadillo homolog pescadillo homolog 1, containing BRCT domain
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_022889.3	NP_075027.1	pescadillo homolog
XM_017314702.1	XP_017170191.1	pescadillo homolog isoform X1

Pathways from BioSystems

Homologies

Kluyveromyces lactis	KLLA0D15268g	XP_453738.1
Mus musculus (house mouse)	Pes1	NP_075027.1
Eremothecium gossypii	AGOS_AAR094W	NP_982635.1
Magnaporthe oryzae (rice blast fungus)	MGG_01183	XP_003714067.1
Bos taurus (cattle)	PES1	NP_001179229.1
Caenorhabditis elegans (roundworm)	lpd-7	NP_498661.1
Danio rerio (zebrafish)	pes	NP_571105.2
Drosophila melanogaster (fruit fly)	CG4364	NP_609305.1
Saccharomyces cerevisiae (baker's yeast)	NOP7	NP_011617.1
Anopheles gambiae (African malaria mosquito)	PESC_ANOGA	XP_308647.4
Schizosaccharomyces pombe (fission yeast)	ppp1	NP_596543.1
Neurospora crassa	NCU00925	XP_964751.1
Pan troglodytes (chimpanzee)	PES1	NP_001233294.1
Macaca mulatta (Rhesus monkey)	PES1	XP_001110399.2
Rattus norvegicus (Norway rat)	Pes1	NP_001037693.1
Homo sapiens (human)	PES1	NP_055118.1
Canis lupus familiaris (dog)	PES1	XP_543480.2
Gallus gallus (chicken)	PES1	XP_001234133.3
Arabidopsis thaliana (thale cress)	AT5G14520	NP_196956.1
Xenopus tropicalis (tropical clawed frog)	pes1	NP_989410.1
Oryza sativa (rice)	Os03g0699200	NP_001050986.1

Gene Ontology
Bibliography

Related articles in PubMed

Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation.
Nakaguro M, Kiyonari S, Kishida S, Cao D, Murakami-Tonami Y, Ichikawa H, Takeuchi I, Nakamura S, Kadomatsu K
Cancer science106(3)237-43(2015 Mar)

Two orthogonal cleavages separate subunit RNAs in mouse ribosome biogenesis.
Wang M, Anikin L, Pestov DG
Nucleic acids research42(17)11180-91(2014)

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L
Developmental cell22(5)913-26(2012 May)

Light chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1.
Lerch-Gaggl AF, Sun K, Duncan SA
The Journal of biological chemistry282(15)11308-16(2007 Apr)

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.
Grimm T, Hölzel M, Rohrmoser M, Harasim T, Malamoussi A, Gruber-Eber A, Kremmer E, Eick D
Nucleic acids research34(10)3030-43(2006)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pes1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pes1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu78002	XM_017314702.1 Latest version!	Mus musculus pescadillo ribosomal biogenesis factor 1 (Pes1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu12655	NM_022889.3 Latest version!	Mus musculus pescadillo ribosomal biogenesis factor 1 (Pes1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$342.30 $489.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pes1 ( XM_017314702.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170191.1 Mus musculus pescadillo ribosomal biogenesis factor 1 (Pes1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu78002
Clone ID Related Accession (Same CDS sequence)	XM_017314702.1
Accession Version	XM_017314702.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	pescadillo homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGGTC TGGAGAAGAA GAAGTATGAA CGAGGCTCTG CCACCAATTA TATCACCCGA 
AACAAGGCCA GGAAGAAGCT GCAGCTGAGC CTGCCTGACT TCAGGCGGCT GTGCATCCTG 
AAAGGTATTT ATCCTCACGA ACCCAAGCAT AAGAAGAAAG TTAACAAGGG TTCCACAGCA 
GCCCGGACAT TTTACCTTAT CAAAGACATT AAATTCCTCC TCCATGAGCC CATCGTCAAC 
AAGTTCCGAG AGTACAAGGT GTTTGTTCGG AAGCTCCGCA AAGCCTATGG AAAGAGCGAA 
TGGAATGCTG TGGAGCGCCT GAAGGACAAT AAACCCTGCT ACAAACTTGA CCACATTGTC 
AAGGAGCGGT ACCCCACATT TATCGATGCT CTGCGGGACC TCGATGATGC CCTGTCAATG 
TGCTTCCTCT TCTCCACCTT CCCTCGGACT GGCAAGTGTC ATGTGCAGAC CATTCAGTTG 
TGCCGTAGGC TCACTGTGGA GTTCCTGCAC TATGTCATCA CTGCCCGAGC CCTGCGCAAG 
GTCTTCCTGT CCATTAAAGG CATTTATTAT CAGGCTGAGG TGCTGGGTCA GCCCATCGTA 
TGGATTGCAC CCTATGCTTT CTCCCATGAT CATCCGACAG ATGTGGACTA CAGGGTCATG 
GCCACCTTCA CTGAGTTCTA TACCACGCTC CTGGGCTTTG TCAACTTCCG TCTCTACCAG 
TCACTCAACC TTCACTACCC ACCAAAGCTT GAAGGTCAAG CCCAAGCAGA GACAAAGATC 
AGCGAGGACA CATATGCATT GGACTCTGAG AGCTCTATGG AGAAACTGGC TGCCCTCAGT 
GCCAGCCTGG CCCGAGTGGT GGTGCCTGCT ATAGAGGAGG CTGAGGCTGA TGAATTCCCT 
ACTGATGGGG AGGTGACAGC ACAGGAGGAA GATCGGAAGA AAGAGCTGGA GGCACAGGAA 
AAGCACAAGA AACTCTTTGA AGGCCTGAAG TTCTTCCTGA ACCGAGAGGT GCCCCGTGAA 
GCATTGGCCT TCATCATCAG GAGTTTTGGT GGGGATGTAT CCTGGGACAA GTCTCTGTGT 
ATCGGAGCCA CCTATGACGT CACAGACTCA TGCATCACCC ACCAGATTGT TGACCGGCCG 
GGGCAGCAAA CCCCCATCAT TGGCAGGTAC TATGTACAGC CCCAGTGGGT CTTTGACTGT 
GTGAATGCCC GGCTCCTCCT CCCTGTGGCA GAGTACTTCC CCGGGATGCA GCTGCCCCCA 
CATCTTTCAC CCTTCGTATC TGAGAAGGAA GGAGATTACA TTCCCCCTGA GAAGCTGAAG 
CTCCTGGCTC TGCAGCGGGG AGAAGACCCA GGACACTTGG AAGAGGAGGA GGAGGAGGAT 
GAAGATGATG ACAACGAAGG TGATGTTGCA GCGGAAAATG AAGAGGAAGA TGTGGAAGTT 
GAATCGGAGG AGGAGGAGGA GGAGGAGGTG CACCTTTCGG CCTTGGAGCA GCACAGGCTG 
GAAGAGAAGG TAGGAAGCAC TAGGCAGCGC TATCCCTGGG AAGCAGCCTG GTTAGCCCAG 
AAGGCCACGT TCACATGCAG ATGCACTGTT CCCCAGAAAC CCCAGGTTAT GGCCGGCACT 
GTGAAGCTGG AAGACAAGCA GCGGCTGGCC CAGGAGGAAG AGAGTGAGGC TAAGCGCTTG 
GCCATCATGA TGATGAAAAA GCGAGAGAAG TACCTTTACC AAAAGATCAT GTTTGGCAAG 
CGGCGCAAAA TCCGAGAGGC CAACAAGCTG GCAGAGAAGA GGAAAGCCCA TGATGATGCT 
GTGAGGTCTG AGAAAAAGGC CAAGAGGACA AGGCCCGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170191.1
CDS	230..2071
Translation	MGGLEKKKYERGSATNYITRNKARKKLQLSLPDFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIKFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNAVERLKDNKPCYKLDHIVKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFLHYVITARALRKVFLSIKGIYYQAEVLGQPIVWIAPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLEGQAQAETKISEDTYALDSESSMEKLAALSASLARVVVPAIEEAEADEFPTDGEVTAQEEDRKKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSLCIGATYDVTDSCITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGMQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGHLEEEEEEDEDDDNEGDVAAENEEEDVEVESEEEEEEEVHLSALEQHRLEEKVGSTRQRYPWEAAWLAQKATFTCRCTVPQKPQVMAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDDAVRSEKKAKRTRPV

Target ORF information:

RefSeq Version	XM_017314702.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus pescadillo ribosomal biogenesis factor 1 (Pes1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017314702.1

ORF Insert Sequence:

ATGGGAGGTC TGGAGAAGAA GAAGTATGAA CGAGGCTCTG CCACCAATTA TATCACCCGA 
AACAAGGCCA GGAAGAAGCT GCAGCTGAGC CTGCCTGACT TCAGGCGGCT GTGCATCCTG 
AAAGGTATTT ATCCTCACGA ACCCAAGCAT AAGAAGAAAG TTAACAAGGG TTCCACAGCA 
GCCCGGACAT TTTACCTTAT CAAAGACATT AAATTCCTCC TCCATGAGCC CATCGTCAAC 
AAGTTCCGAG AGTACAAGGT GTTTGTTCGG AAGCTCCGCA AAGCCTATGG AAAGAGCGAA 
TGGAATGCTG TGGAGCGCCT GAAGGACAAT AAACCCTGCT ACAAACTTGA CCACATTGTC 
AAGGAGCGGT ACCCCACATT TATCGATGCT CTGCGGGACC TCGATGATGC CCTGTCAATG 
TGCTTCCTCT TCTCCACCTT CCCTCGGACT GGCAAGTGTC ATGTGCAGAC CATTCAGTTG 
TGCCGTAGGC TCACTGTGGA GTTCCTGCAC TATGTCATCA CTGCCCGAGC CCTGCGCAAG 
GTCTTCCTGT CCATTAAAGG CATTTATTAT CAGGCTGAGG TGCTGGGTCA GCCCATCGTA 
TGGATTGCAC CCTATGCTTT CTCCCATGAT CATCCGACAG ATGTGGACTA CAGGGTCATG 
GCCACCTTCA CTGAGTTCTA TACCACGCTC CTGGGCTTTG TCAACTTCCG TCTCTACCAG 
TCACTCAACC TTCACTACCC ACCAAAGCTT GAAGGTCAAG CCCAAGCAGA GACAAAGATC 
AGCGAGGACA CATATGCATT GGACTCTGAG AGCTCTATGG AGAAACTGGC TGCCCTCAGT 
GCCAGCCTGG CCCGAGTGGT GGTGCCTGCT ATAGAGGAGG CTGAGGCTGA TGAATTCCCT 
ACTGATGGGG AGGTGACAGC ACAGGAGGAA GATCGGAAGA AAGAGCTGGA GGCACAGGAA 
AAGCACAAGA AACTCTTTGA AGGCCTGAAG TTCTTCCTGA ACCGAGAGGT GCCCCGTGAA 
GCATTGGCCT TCATCATCAG GAGTTTTGGT GGGGATGTAT CCTGGGACAA GTCTCTGTGT 
ATCGGAGCCA CCTATGACGT CACAGACTCA TGCATCACCC ACCAGATTGT TGACCGGCCG 
GGGCAGCAAA CCCCCATCAT TGGCAGGTAC TATGTACAGC CCCAGTGGGT CTTTGACTGT 
GTGAATGCCC GGCTCCTCCT CCCTGTGGCA GAGTACTTCC CCGGGATGCA GCTGCCCCCA 
CATCTTTCAC CCTTCGTATC TGAGAAGGAA GGAGATTACA TTCCCCCTGA GAAGCTGAAG 
CTCCTGGCTC TGCAGCGGGG AGAAGACCCA GGACACTTGG AAGAGGAGGA GGAGGAGGAT 
GAAGATGATG ACAACGAAGG TGATGTTGCA GCGGAAAATG AAGAGGAAGA TGTGGAAGTT 
GAATCGGAGG AGGAGGAGGA GGAGGAGGTG CACCTTTCGG CCTTGGAGCA GCACAGGCTG 
GAAGAGAAGG TAGGAAGCAC TAGGCAGCGC TATCCCTGGG AAGCAGCCTG GTTAGCCCAG 
AAGGCCACGT TCACATGCAG ATGCACTGTT CCCCAGAAAC CCCAGGTTAT GGCCGGCACT 
GTGAAGCTGG AAGACAAGCA GCGGCTGGCC CAGGAGGAAG AGAGTGAGGC TAAGCGCTTG 
GCCATCATGA TGATGAAAAA GCGAGAGAAG TACCTTTACC AAAAGATCAT GTTTGGCAAG 
CGGCGCAAAA TCCGAGAGGC CAACAAGCTG GCAGAGAAGA GGAAAGCCCA TGATGATGCT 
GTGAGGTCTG AGAAAAAGGC CAAGAGGACA AGGCCCGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pes1 ( NM_022889.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_075027.1 Mus musculus pescadillo ribosomal biogenesis factor 1 (Pes1), mRNA.

Price & Availability↑

CloneID	OMu12655
Clone ID Related Accession (Same CDS sequence)	NM_022889.3
Accession Version	NM_022889.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564675200000
Organism	Mus musculus(house mouse)
Product	pescadillo homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL807395.8. On Nov 17, 2006 this sequence version replaced NM_022889.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK029075.1, BC004844.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGAGGTC TGGAGAAGAA GAAGTATGAA CGAGGCTCTG CCACCAATTA TATCACCCGA 
AACAAGGCCA GGAAGAAGCT GCAGCTGAGC CTGCCTGACT TCAGGCGGCT GTGCATCCTG 
AAAGGTATTT ATCCTCACGA ACCCAAGCAT AAGAAGAAAG TTAACAAGGG TTCCACAGCA 
GCCCGGACAT TTTACCTTAT CAAAGACATT AAATTCCTCC TCCATGAGCC CATCGTCAAC 
AAGTTCCGAG AGTACAAGGT GTTTGTTCGG AAGCTCCGCA AAGCCTATGG AAAGAGCGAA 
TGGAATGCTG TGGAGCGCCT GAAGGACAAT AAACCCTGCT ACAAACTTGA CCACATTGTC 
AAGGAGCGGT ACCCCACATT TATCGATGCT CTGCGGGACC TCGATGATGC CCTGTCAATG 
TGCTTCCTCT TCTCCACCTT CCCTCGGACT GGCAAGTGTC ATGTGCAGAC CATTCAGTTG 
TGCCGTAGGC TCACTGTGGA GTTCCTGCAC TATGTCATCA CTGCCCGAGC CCTGCGCAAG 
GTCTTCCTGT CCATTAAAGG CATTTATTAT CAGGCTGAGG TGCTGGGTCA GCCCATCGTA 
TGGATTGCAC CCTATGCTTT CTCCCATGAT CATCCGACAG ATGTGGACTA CAGGGTCATG 
GCCACCTTCA CTGAGTTCTA TACCACGCTC CTGGGCTTTG TCAACTTCCG TCTCTACCAG 
TCACTCAACC TTCACTACCC ACCAAAGCTT GAAGGTCAAG CCCAAGCAGA GACAAAGATC 
AGCGAGGACA CATATGCATT GGACTCTGAG AGCTCTATGG AGAAACTGGC TGCCCTCAGT 
GCCAGCCTGG CCCGAGTGGT GGTGCCTGCT ATAGAGGAGG CTGAGGCTGA TGAATTCCCT 
ACTGATGGGG AGGTGACAGC ACAGGAGGAA GATCGGAAGA AAGAGCTGGA GGCACAGGAA 
AAGCACAAGA AACTCTTTGA AGGCCTGAAG TTCTTCCTGA ACCGAGAGGT GCCCCGTGAA 
GCATTGGCCT TCATCATCAG GAGTTTTGGT GGGGATGTAT CCTGGGACAA GTCTCTGTGT 
ATCGGAGCCA CCTATGACGT CACAGACTCA TGCATCACCC ACCAGATTGT TGACCGGCCG 
GGGCAGCAAA CCCCCATCAT TGGCAGGTAC TATGTACAGC CCCAGTGGGT CTTTGACTGT 
GTGAATGCCC GGCTCCTCCT CCCTGTGGCA GAGTACTTCC CCGGGATGCA GCTGCCCCCA 
CATCTTTCAC CCTTCGTATC TGAGAAGGAA GGAGATTACA TTCCCCCTGA GAAGCTGAAG 
CTCCTGGCTC TGCAGCGGGG AGAAGACCCA GGACACTTGG AAGAGGAGGA GGAGGAGGAT 
GAAGATGATG ACAACGAAGG TGATGTTGCA GCGGAAAATG AAGAGGAAGA TGTGGAAGTT 
GAATCGGAGG AGGAGGAGGA GGAGGAGGTG CACCTTTCGG CCTTGGAGCA GCACAGGCTG 
GAAGAGAAGA AACCCCAGGT TATGGCCGGC ACTGTGAAGC TGGAAGACAA GCAGCGGCTG 
GCCCAGGAGG AAGAGAGTGA GGCTAAGCGC TTGGCCATCA TGATGATGAA AAAGCGAGAG 
AAGTACCTTT ACCAAAAGAT CATGTTTGGC AAGCGGCGCA AAATCCGAGA GGCCAACAAG 
CTGGCAGAGA AGAGGAAAGC CCATGATGAT GCTGTGAGGT CTGAGAAAAA GGCCAAGAGG 
ACAAGGCCCG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075027.1
CDS	63..1817
Translation	MGGLEKKKYERGSATNYITRNKARKKLQLSLPDFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIKFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNAVERLKDNKPCYKLDHIVKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFLHYVITARALRKVFLSIKGIYYQAEVLGQPIVWIAPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLEGQAQAETKISEDTYALDSESSMEKLAALSASLARVVVPAIEEAEADEFPTDGEVTAQEEDRKKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSLCIGATYDVTDSCITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGMQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGHLEEEEEEDEDDDNEGDVAAENEEEDVEVESEEEEEEEVHLSALEQHRLEEKKPQVMAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDDAVRSEKKAKRTRPV

Target ORF information:

RefSeq Version	NM_022889.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus pescadillo ribosomal biogenesis factor 1 (Pes1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022889.3

ORF Insert Sequence:

ATGGGAGGTC TGGAGAAGAA GAAGTATGAA CGAGGCTCTG CCACCAATTA TATCACCCGA 
AACAAGGCCA GGAAGAAGCT GCAGCTGAGC CTGCCTGACT TCAGGCGGCT GTGCATCCTG 
AAAGGTATTT ATCCTCACGA ACCCAAGCAT AAGAAGAAAG TTAACAAGGG TTCCACAGCA 
GCCCGGACAT TTTACCTTAT CAAAGACATT AAATTCCTCC TCCATGAGCC CATCGTCAAC 
AAGTTCCGAG AGTACAAGGT GTTTGTTCGG AAGCTCCGCA AAGCCTATGG AAAGAGCGAA 
TGGAATGCTG TGGAGCGCCT GAAGGACAAT AAACCCTGCT ACAAACTTGA CCACATTGTC 
AAGGAGCGGT ACCCCACATT TATCGATGCT CTGCGGGACC TCGATGATGC CCTGTCAATG 
TGCTTCCTCT TCTCCACCTT CCCTCGGACT GGCAAGTGTC ATGTGCAGAC CATTCAGTTG 
TGCCGTAGGC TCACTGTGGA GTTCCTGCAC TATGTCATCA CTGCCCGAGC CCTGCGCAAG 
GTCTTCCTGT CCATTAAAGG CATTTATTAT CAGGCTGAGG TGCTGGGTCA GCCCATCGTA 
TGGATTGCAC CCTATGCTTT CTCCCATGAT CATCCGACAG ATGTGGACTA CAGGGTCATG 
GCCACCTTCA CTGAGTTCTA TACCACGCTC CTGGGCTTTG TCAACTTCCG TCTCTACCAG 
TCACTCAACC TTCACTACCC ACCAAAGCTT GAAGGTCAAG CCCAAGCAGA GACAAAGATC 
AGCGAGGACA CATATGCATT GGACTCTGAG AGCTCTATGG AGAAACTGGC TGCCCTCAGT 
GCCAGCCTGG CCCGAGTGGT GGTGCCTGCT ATAGAGGAGG CTGAGGCTGA TGAATTCCCT 
ACTGATGGGG AGGTGACAGC ACAGGAGGAA GATCGGAAGA AAGAGCTGGA GGCACAGGAA 
AAGCACAAGA AACTCTTTGA AGGCCTGAAG TTCTTCCTGA ACCGAGAGGT GCCCCGTGAA 
GCATTGGCCT TCATCATCAG GAGTTTTGGT GGGGATGTAT CCTGGGACAA GTCTCTGTGT 
ATCGGAGCCA CCTATGACGT CACAGACTCA TGCATCACCC ACCAGATTGT TGACCGGCCG 
GGGCAGCAAA CCCCCATCAT TGGCAGGTAC TATGTACAGC CCCAGTGGGT CTTTGACTGT 
GTGAATGCCC GGCTCCTCCT CCCTGTGGCA GAGTACTTCC CCGGGATGCA GCTGCCCCCA 
CATCTTTCAC CCTTCGTATC TGAGAAGGAA GGAGATTACA TTCCCCCTGA GAAGCTGAAG 
CTCCTGGCTC TGCAGCGGGG AGAAGACCCA GGACACTTGG AAGAGGAGGA GGAGGAGGAT 
GAAGATGATG ACAACGAAGG TGATGTTGCA GCGGAAAATG AAGAGGAAGA TGTGGAAGTT 
GAATCGGAGG AGGAGGAGGA GGAGGAGGTG CACCTTTCGG CCTTGGAGCA GCACAGGCTG 
GAAGAGAAGA AACCCCAGGT TATGGCCGGC ACTGTGAAGC TGGAAGACAA GCAGCGGCTG 
GCCCAGGAGG AAGAGAGTGA GGCTAAGCGC TTGGCCATCA TGATGATGAA AAAGCGAGAG 
AAGTACCTTT ACCAAAAGAT CATGTTTGGC AAGCGGCGCA AAATCCGAGA GGCCAACAAG 
CTGGCAGAGA AGAGGAAAGC CCATGATGAT GCTGTGAGGT CTGAGAAAAA GGCCAAGAGG 
ACAAGGCCCG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation.
Cancer science106(3)237-43(2015 Mar)
Nakaguro M,Kiyonari S,Kishida S,Cao D,Murakami-Tonami Y,Ichikawa H,Takeuchi I,Nakamura S,Kadomatsu K

Two orthogonal cleavages separate subunit RNAs in mouse ribosome biogenesis.
Nucleic acids research42(17)11180-91(2014)
Wang M,Anikin L,Pestov DG

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Developmental cell22(5)913-26(2012 May)
Koss M,Bolze A,Brendolan A,Saggese M,Capellini TD,Bojilova E,Boisson B,Prall OW,Elliott DA,Solloway M,Lenti E,Hidaka C,Chang CP,Mahlaoui N,Harvey RP,Casanova JL,Selleri L

Light chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1.
The Journal of biological chemistry282(15)11308-16(2007 Apr)
Lerch-Gaggl AF,Sun K,Duncan SA

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.
Nucleic acids research34(10)3030-43(2006)
Grimm T,Hölzel M,Rohrmoser M,Harasim T,Malamoussi A,Gruber-Eber A,Kremmer E,Eick D

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Pes1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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