Ireb2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ireb2
Entrez Gene ID	64602
Full Name	iron responsive element binding protein 2
Synonyms	D9Ertd85e,Irp2
General protein information	Preferred Names iron responsive element binding protein 2 Names iron-responsive element-binding protein 2 IRE-BP 2 iron regulatory protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 B\|9 29.81 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_022655.3	NP_073146.2	iron-responsive element-binding protein 2
XM_006511335.3	XP_006511398.1	iron-responsive element-binding protein 2 isoform X1
XM_006511335.4	XP_006511398.1	iron-responsive element-binding protein 2 isoform X1
XM_017313499.1	XP_017168988.1	iron-responsive element-binding protein 2 isoform X2
XM_017313500.1	XP_017168989.1	iron-responsive element-binding protein 2 isoform X3

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	IREB2	XP_001107837.1
Mus musculus (house mouse)	Ireb2	NP_073146.2
Rattus norvegicus (Norway rat)	Ireb2	NP_074054.2
Danio rerio (zebrafish)	ireb2	XP_005163029.1
Pan troglodytes (chimpanzee)	IREB2	XP_523125.2
Bos taurus (cattle)	IREB2	XP_002696712.2
Gallus gallus (chicken)	IREB2	NP_001026625.1
Homo sapiens (human)	IREB2	NP_004127.1
Xenopus tropicalis (tropical clawed frog)	ireb2	NP_001072764.1
Canis lupus familiaris (dog)	IREB2	XP_532364.2

Gene Ontology
Bibliography

Related articles in PubMed

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.
Muto Y, Moroishi T, Ichihara K, Nishiyama M, Shimizu H, Eguchi H, Moriya K, Koike K, Mimori K, Mori M, Katayama Y, Nakayama KI
The Journal of experimental medicine216(4)950-965(2019 Apr)

Iron regulatory protein 2 deficiency may correlate with insulin resistance.
Zhou Y, Wu W, Xu Z, Liu Y, Chang H, Yu P, Zhang X, Yang Y, Liu K, Chang Y
Biochemical and biophysical research communications510(2)191-197(2019 03)

Leishmania donovani inhibits ferroportin translation by modulating FBXL5-IRP2 axis for its growth within host macrophages.
Das NK, Sandhya S, G VV, Kumar R, Singh AK, Bal SK, Kumari S, Mukhopadhyay CK
Cellular microbiology20(7)e12834(2018 07)

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.
Muto Y, Nishiyama M, Nita A, Moroishi T, Nakayama KI
Nature communications816114(2017 07)

FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.
Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama KI
Molecular and cellular biology37(8)(2017 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ireb2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ireb2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu12634	NM_022655.3 Latest version!	Mus musculus iron responsive element binding protein 2 (Ireb2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu42904	XM_006511335.4 Latest version!	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu82898	XM_017313499.1 Latest version!	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu82899	XM_017313500.1 Latest version!	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu42904	XM_006511335.3	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ireb2 ( NM_022655.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_073146.2 Mus musculus iron responsive element binding protein 2 (Ireb2), mRNA.

Price & Availability↑

CloneID	OMu12634
Clone ID Related Accession (Same CDS sequence)	NM_022655.3
Accession Version	NM_022655.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574006400000
Organism	Mus musculus(house mouse)
Product	iron-responsive element-binding protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ093933.1, CN534597.1, CK636500.1, CN664620.1, CV558274.1, CO431396.1 and AC161264.2. On Jul 18, 2009 this sequence version replaced NM_022655.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATGG GAAATAAACG GTGGAATTCG 
TTAGAAGCTC CAGACTCCGT GCTGTTTCCA TGGGATGTGA AGTCTACTTA CATCAGATGC 
CCTTCATTTT TTGATAAGCT TACCAAAGAG CCAGCTGCAT CCCAGCCTAT TGAGAATGCC 
CATGTCCTGT TGTATTTGGG AGACTCTGTC ACTACAGATC ATATATCACC CGCTGGAAGT 
ATTGCTAGGA GTAGTGCTGC TGCTAAGTAT TTGACAAACA GAGGCCTTAC TCCCCGAGAG 
TTCAACTCTT ATGGAGCTCG AAGAGGTAAT GATGCTGTGA TGACAAGAGG CACATTTGCA 
AACATCAAGC TTTTTAATAA GTTTATTGGG AAGCCAGCTC CCAAAACAAT TCATTTTCCA 
TCGGGACAAA CGCTCGATGT ATTTGAAGCT GCAGAACTGT ACCAGAAAGA AGGTATCCCA 
CTGATAATTT TAGCAGGAAA AAAATATGGT TCAGGAAATT CAAGAGATTG GGCTGCCAAG 
GGACCCTATT TGCTGGGTGT AAAAGCTGTT TTGGCTGAGA GCTATGAAAA AATACACAAA 
GATCATTTGA TTGGAATTGG TATAGCACCA CTTGAATTCC TCCCAGGAGA AAATGCAGAT 
TCCTTGGGCC TCTCTGGCAG AGAAGTATTT TCTTTATCAT TTCCTGAAGA ACTCTTTCCT 
GGAATTACAT TAAATATAAA GACAAGCACT GGAAAAGAGT TCAGCGTGAT TGCATCATTT 
GCAAATGACG TGGAGATAAC TTTGTACAAA CATGGAGGCT TATTAAACTT TGTGGCTCGA 
AAATTCTTAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073146.2
CDS	124..3015
Translation	MDSPSAGYTFEYLIETLNGNSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVVLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQSKKLPCRGQTTCRGSCDSGELSRNSGTFSSQIENTPVLCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSGAFKNVAVIPPGTGMAHQVNLEYLSRVVFEETDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTGFDKTKLESMEKYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEIGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFDIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGVLSGNKHFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKEIYLHDIWPSREEVHQMEEEHVILSMFKTLKEKVEMGNKRWNSLEAPDSVLFPWDVKSTYIRCPSFFDKLTKEPAASQPIENAHVLLYLGDSVTTDHISPAGSIARSSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLEFLPGENADSLGLSGREVFSLSFPEELFPGITLNIKTSTGKEFSVIASFANDVEITLYKHGGLLNFVARKFL

Target ORF information:

RefSeq Version	NM_022655.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus iron responsive element binding protein 2 (Ireb2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022655.3

ORF Insert Sequence:

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATGG GAAATAAACG GTGGAATTCG 
TTAGAAGCTC CAGACTCCGT GCTGTTTCCA TGGGATGTGA AGTCTACTTA CATCAGATGC 
CCTTCATTTT TTGATAAGCT TACCAAAGAG CCAGCTGCAT CCCAGCCTAT TGAGAATGCC 
CATGTCCTGT TGTATTTGGG AGACTCTGTC ACTACAGATC ATATATCACC CGCTGGAAGT 
ATTGCTAGGA GTAGTGCTGC TGCTAAGTAT TTGACAAACA GAGGCCTTAC TCCCCGAGAG 
TTCAACTCTT ATGGAGCTCG AAGAGGTAAT GATGCTGTGA TGACAAGAGG CACATTTGCA 
AACATCAAGC TTTTTAATAA GTTTATTGGG AAGCCAGCTC CCAAAACAAT TCATTTTCCA 
TCGGGACAAA CGCTCGATGT ATTTGAAGCT GCAGAACTGT ACCAGAAAGA AGGTATCCCA 
CTGATAATTT TAGCAGGAAA AAAATATGGT TCAGGAAATT CAAGAGATTG GGCTGCCAAG 
GGACCCTATT TGCTGGGTGT AAAAGCTGTT TTGGCTGAGA GCTATGAAAA AATACACAAA 
GATCATTTGA TTGGAATTGG TATAGCACCA CTTGAATTCC TCCCAGGAGA AAATGCAGAT 
TCCTTGGGCC TCTCTGGCAG AGAAGTATTT TCTTTATCAT TTCCTGAAGA ACTCTTTCCT 
GGAATTACAT TAAATATAAA GACAAGCACT GGAAAAGAGT TCAGCGTGAT TGCATCATTT 
GCAAATGACG TGGAGATAAC TTTGTACAAA CATGGAGGCT TATTAAACTT TGTGGCTCGA 
AAATTCTTAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ireb2 ( XM_006511335.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006511398.1 Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu42904
Clone ID Related Accession (Same CDS sequence)	XM_006511335.3 , XM_006511335.4
Accession Version	XM_006511335.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	iron-responsive element-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006511335.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATTC TACATGTGCG ATATTTATCT 
TTATTTTTAC TTTCATATTA TCCCTTATTC CCCTTCCCCC CTTGTCCTCT TTCTACTATT 
ATATTTGAAT CTAGATTCTC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511398.1
CDS	214..2400
Translation	MDSPSAGYTFEYLIETLNGNSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVVLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQSKKLPCRGQTTCRGSCDSGELSRNSGTFSSQIENTPVLCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSGAFKNVAVIPPGTGMAHQVNLEYLSRVVFEETDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTGFDKTKLESMEKYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEIGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFDIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGVLSGNKHFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKEIYLHDIWPSREEVHQMEEEHVILSMFKTLKEKVEILHVRYLSLFLLSYYPLFPFPPCPLSTIIFESRFSK

Target ORF information:

RefSeq Version	XM_006511335.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511335.3

ORF Insert Sequence:

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATTC TACATGTGCG ATATTTATCT 
TTATTTTTAC TTTCATATTA TCCCTTATTC CCCTTCCCCC CTTGTCCTCT TTCTACTATT 
ATATTTGAAT CTAGATTCTC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ireb2 ( XM_006511335.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006511398.1 Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu42904
Clone ID Related Accession (Same CDS sequence)	XM_006511335.3 , XM_006511335.4
Accession Version	XM_006511335.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	iron-responsive element-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006511335.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATTC TACATGTGCG ATATTTATCT 
TTATTTTTAC TTTCATATTA TCCCTTATTC CCCTTCCCCC CTTGTCCTCT TTCTACTATT 
ATATTTGAAT CTAGATTCTC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511398.1
CDS	1221..3407
Translation	MDSPSAGYTFEYLIETLNGNSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVVLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQSKKLPCRGQTTCRGSCDSGELSRNSGTFSSQIENTPVLCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSGAFKNVAVIPPGTGMAHQVNLEYLSRVVFEETDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTGFDKTKLESMEKYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEIGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFDIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGVLSGNKHFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKEIYLHDIWPSREEVHQMEEEHVILSMFKTLKEKVEILHVRYLSLFLLSYYPLFPFPPCPLSTIIFESRFSK

Target ORF information:

RefSeq Version	XM_006511335.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511335.4

ORF Insert Sequence:

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATTC TACATGTGCG ATATTTATCT 
TTATTTTTAC TTTCATATTA TCCCTTATTC CCCTTCCCCC CTTGTCCTCT TTCTACTATT 
ATATTTGAAT CTAGATTCTC CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ireb2 ( XM_017313499.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017168988.1 Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu82898
Clone ID Related Accession (Same CDS sequence)	XM_017313499.1
Accession Version	XM_017313499.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	iron-responsive element-binding protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCATC AAGTGAACTT AGAATATTTA TCAAGAGTAG TTTTTGAAGA AACGGACCTG 
CTCTTCCCAG ACAGTGTAGT TGGCACAGAT TCTCATATAA CCATGGTGAA CGGATTGGGG 
ATTCTTGGGT GGGGAGTTGG TGGCATTGAG ACAGAGGCAG TTATGCTTGG CCTGCCAGTT 
ACTCTTACTT TACCAGAGGT GGTTGGATGT GAGCTAACTG GGTCATCCAA TGCTTTTGTT 
ACATCCATAG ATATTGTCCT TGGCATTACA AAGCACCTCA GGCAAGTAGG CGTGGCTGGA 
AAGTTTGTTG AGTTCTTTGG AAGTGGAGTT TCACAATTAT CTATTGTCGA TAGAACTACC 
ATAGCAAACA TGTGTCCAGA ATATGGTGCT ATCCTCAGCT TTTTCCCTGT TGACAATGTG 
ACACTACGAC ATTTAGAACA TACAGGTTTT GACAAAACCA AACTTGAGTC AATGGAAAAA 
TACCTTAAAG CTGTGAAATT GTTTCGAAAT GATGAGAATT CTTCAGAACC TGAATATTCT 
CAGGTGATAC AGATTAATCT GAATTCAATA GTTGCATCTG TCAGTGGTCC AAAAAGGCCT 
CAGGATAGGG TTGCTGTAAC AGATATGAAA AGTGATTTTC AGGCTTGCTT AAATGAAAAG 
GTTGGATTTA AAGGCTTCCA AGTTGCAGCA GAAAAACAAA GTGACACTGT CTCTGTTCGT 
TATGATGGAA GTGAGTATAA GCTGTCCCAT GGATCCGTGG TCATTGCTGC AGTTATCAGT 
TGTACCAATA ATTGCAATCC ATCTGTGATG CTTGCTGCAG GTCTTCTGGC TAAAAAGGCT 
GTTGAAATTG GTCTACGAGT TAAACCTTAT ATACGAACAA GTTTGTCTCC AGGCAGTGGG 
ATGGTTACAC ATTACCTCAG TTCAAGTGGA GTGCTACCCT ATCTTAGCAA GCTAGGGTTT 
GACATAGTTG GCTATGGATG TTCAACATGT GTAGGAAATA CAGCACCTTT ATCAGAAGCA 
GTTTTGAATG CAGTAAAACA GGGTGATTTG GTTACCTGTG GAGTTTTATC TGGAAACAAA 
CATTTCGAAG GCCGTCTCTG TGATTGTGTC CGTGCCAATT ATCTCGCCTC TCCGCCCTTA 
GTGGTGGCTT ATGCCATAGC AGGCACAGTG AATATAGACT TCCAGACAGA GCCTTTAGGT 
ACTGACTCTA CGGGCAAGGA AATTTACCTG CATGACATTT GGCCTAGTCG AGAAGAAGTT 
CATCAGATGG AGGAAGAACA TGTTATATTG TCAATGTTTA AAACACTAAA AGAGAAAGTA 
GAGATGGGAA ATAAACGGTG GAATTCGTTA GAAGCTCCAG ACTCCGTGCT GTTTCCATGG 
GATGTGAAGT CTACTTACAT CAGATGCCCT TCATTTTTTG ATAAGCTTAC CAAAGAGCCA 
GCTGCATCCC AGCCTATTGA GAATGCCCAT GTCCTGTTGT ATTTGGGAGA CTCTGTCACT 
ACAGATCATA TATCACCCGC TGGAAGTATT GCTAGGAGTA GTGCTGCTGC TAAGTATTTG 
ACAAACAGAG GCCTTACTCC CCGAGAGTTC AACTCTTATG GAGCTCGAAG AGGTAATGAT 
GCTGTGATGA CAAGAGGCAC ATTTGCAAAC ATCAAGCTTT TTAATAAGTT TATTGGGAAG 
CCAGCTCCCA AAACAATTCA TTTTCCATCG GGACAAACGC TCGATGTATT TGAAGCTGCA 
GAACTGTACC AGAAAGAAGG TATCCCACTG ATAATTTTAG CAGGAAAAAA ATATGGTTCA 
GGAAATTCAA GAGATTGGGC TGCCAAGGGA CCCTATTTGC TGGGTGTAAA AGCTGTTTTG 
GCTGAGAGCT ATGAAAAAAT ACACAAAGAT CATTTGATTG GAATTGGTAT AGCACCACTT 
GAATTCCTCC CAGGAGAAAA TGCAGATTCC TTGGGCCTCT CTGGCAGAGA AGTATTTTCT 
TTATCATTTC CTGAAGAACT CTTTCCTGGA ATTACATTAA ATATAAAGAC AAGCACTGGA 
AAAGAGTTCA GCGTGATTGC ATCATTTGCA AATGACGTGG AGATAACTTT GTACAAACAT 
GGAGGCTTAT TAAACTTTGT GGCTCGAAAA TTCTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017168988.1
CDS	370..2508
Translation	MAHQVNLEYLSRVVFEETDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTGFDKTKLESMEKYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEIGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFDIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGVLSGNKHFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKEIYLHDIWPSREEVHQMEEEHVILSMFKTLKEKVEMGNKRWNSLEAPDSVLFPWDVKSTYIRCPSFFDKLTKEPAASQPIENAHVLLYLGDSVTTDHISPAGSIARSSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLEFLPGENADSLGLSGREVFSLSFPEELFPGITLNIKTSTGKEFSVIASFANDVEITLYKHGGLLNFVARKFL

Target ORF information:

RefSeq Version	XM_017313499.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017313499.1

ORF Insert Sequence:

ATGGCTCATC AAGTGAACTT AGAATATTTA TCAAGAGTAG TTTTTGAAGA AACGGACCTG 
CTCTTCCCAG ACAGTGTAGT TGGCACAGAT TCTCATATAA CCATGGTGAA CGGATTGGGG 
ATTCTTGGGT GGGGAGTTGG TGGCATTGAG ACAGAGGCAG TTATGCTTGG CCTGCCAGTT 
ACTCTTACTT TACCAGAGGT GGTTGGATGT GAGCTAACTG GGTCATCCAA TGCTTTTGTT 
ACATCCATAG ATATTGTCCT TGGCATTACA AAGCACCTCA GGCAAGTAGG CGTGGCTGGA 
AAGTTTGTTG AGTTCTTTGG AAGTGGAGTT TCACAATTAT CTATTGTCGA TAGAACTACC 
ATAGCAAACA TGTGTCCAGA ATATGGTGCT ATCCTCAGCT TTTTCCCTGT TGACAATGTG 
ACACTACGAC ATTTAGAACA TACAGGTTTT GACAAAACCA AACTTGAGTC AATGGAAAAA 
TACCTTAAAG CTGTGAAATT GTTTCGAAAT GATGAGAATT CTTCAGAACC TGAATATTCT 
CAGGTGATAC AGATTAATCT GAATTCAATA GTTGCATCTG TCAGTGGTCC AAAAAGGCCT 
CAGGATAGGG TTGCTGTAAC AGATATGAAA AGTGATTTTC AGGCTTGCTT AAATGAAAAG 
GTTGGATTTA AAGGCTTCCA AGTTGCAGCA GAAAAACAAA GTGACACTGT CTCTGTTCGT 
TATGATGGAA GTGAGTATAA GCTGTCCCAT GGATCCGTGG TCATTGCTGC AGTTATCAGT 
TGTACCAATA ATTGCAATCC ATCTGTGATG CTTGCTGCAG GTCTTCTGGC TAAAAAGGCT 
GTTGAAATTG GTCTACGAGT TAAACCTTAT ATACGAACAA GTTTGTCTCC AGGCAGTGGG 
ATGGTTACAC ATTACCTCAG TTCAAGTGGA GTGCTACCCT ATCTTAGCAA GCTAGGGTTT 
GACATAGTTG GCTATGGATG TTCAACATGT GTAGGAAATA CAGCACCTTT ATCAGAAGCA 
GTTTTGAATG CAGTAAAACA GGGTGATTTG GTTACCTGTG GAGTTTTATC TGGAAACAAA 
CATTTCGAAG GCCGTCTCTG TGATTGTGTC CGTGCCAATT ATCTCGCCTC TCCGCCCTTA 
GTGGTGGCTT ATGCCATAGC AGGCACAGTG AATATAGACT TCCAGACAGA GCCTTTAGGT 
ACTGACTCTA CGGGCAAGGA AATTTACCTG CATGACATTT GGCCTAGTCG AGAAGAAGTT 
CATCAGATGG AGGAAGAACA TGTTATATTG TCAATGTTTA AAACACTAAA AGAGAAAGTA 
GAGATGGGAA ATAAACGGTG GAATTCGTTA GAAGCTCCAG ACTCCGTGCT GTTTCCATGG 
GATGTGAAGT CTACTTACAT CAGATGCCCT TCATTTTTTG ATAAGCTTAC CAAAGAGCCA 
GCTGCATCCC AGCCTATTGA GAATGCCCAT GTCCTGTTGT ATTTGGGAGA CTCTGTCACT 
ACAGATCATA TATCACCCGC TGGAAGTATT GCTAGGAGTA GTGCTGCTGC TAAGTATTTG 
ACAAACAGAG GCCTTACTCC CCGAGAGTTC AACTCTTATG GAGCTCGAAG AGGTAATGAT 
GCTGTGATGA CAAGAGGCAC ATTTGCAAAC ATCAAGCTTT TTAATAAGTT TATTGGGAAG 
CCAGCTCCCA AAACAATTCA TTTTCCATCG GGACAAACGC TCGATGTATT TGAAGCTGCA 
GAACTGTACC AGAAAGAAGG TATCCCACTG ATAATTTTAG CAGGAAAAAA ATATGGTTCA 
GGAAATTCAA GAGATTGGGC TGCCAAGGGA CCCTATTTGC TGGGTGTAAA AGCTGTTTTG 
GCTGAGAGCT ATGAAAAAAT ACACAAAGAT CATTTGATTG GAATTGGTAT AGCACCACTT 
GAATTCCTCC CAGGAGAAAA TGCAGATTCC TTGGGCCTCT CTGGCAGAGA AGTATTTTCT 
TTATCATTTC CTGAAGAACT CTTTCCTGGA ATTACATTAA ATATAAAGAC AAGCACTGGA 
AAAGAGTTCA GCGTGATTGC ATCATTTGCA AATGACGTGG AGATAACTTT GTACAAACAT 
GGAGGCTTAT TAAACTTTGT GGCTCGAAAA TTCTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ireb2 ( XM_017313500.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017168989.1 Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu82899
Clone ID Related Accession (Same CDS sequence)	XM_017313500.1
Accession Version	XM_017313500.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2331bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	iron-responsive element-binding protein 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATGG GAAATAAACG GTGGAATTCG 
TTAGAAGCTC CAGACTCCGT GCTGTTTCCA TGGGATGTGA AGTCTACTTA CATCAGATGC 
CCTTCATTTT TTGATAAGCT TGTAAGTACC AGTGTACTAC CAAAGAGCCA GCTGCATCCC 
AGCCTATTGA GAATGCCCAT GTCCTGTTGT ATTTGGGAGA CTCTGTCACT ACAGATCATA 
TATCACCCGC TGGAAGTATT GCTAGGAGTA GTGCTGCTGC TAAGTATTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017168989.1
CDS	178..2508
Translation	MDSPSAGYTFEYLIETLNGNSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVVLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQSKKLPCRGQTTCRGSCDSGELSRNSGTFSSQIENTPVLCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSGAFKNVAVIPPGTGMAHQVNLEYLSRVVFEETDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTGFDKTKLESMEKYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEIGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFDIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGVLSGNKHFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKEIYLHDIWPSREEVHQMEEEHVILSMFKTLKEKVEMGNKRWNSLEAPDSVLFPWDVKSTYIRCPSFFDKLVSTSVLPKSQLHPSLLRMPMSCCIWETLSLQIIYHPLEVLLGVVLLLSI

Target ORF information:

RefSeq Version	XM_017313500.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus iron responsive element binding protein 2 (Ireb2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017313500.1

ORF Insert Sequence:

ATGGACTCCC CAAGTGCAGG ATACACCTTT GAGTACCTTA TTGAAACATT AAATGGCAAT 
TCACAGAAGA AGTTCTTCAA TGTACCTAAA CTTGGCGGCA CCAAGTATGA TATTCTGCCT 
TACTCAATAC GGGTCCTATT GGAAGCTGCT GTACGAAATT GTGATGGCTT TTTAATGAAA 
AAGGAAGATG TTATGAACAT TTTGGACTGG AAAACCAAAC AGAGCAATGT TGAAGTGCCC 
TTTTTCCCTG CCCGTGTTGT TCTTCAAGAT TTCACTGGAA TACCGGCAAT GGTGGATTTT 
GCTGCTATGA GGGAGGCAGT GAAAACTCTT GGAGGTGATC CTAAGAAAGT CCACCCTGCC 
TGTCCGACAG ATCTCACAGT GGACCACTCT TTACAGATTG ACTTCAGTAA ATGTGCAATA 
CAGAATGCAC CAAATCCTGG AGGTGGTGAC CTACAGAAAG CAGGAAAGCT CTCTCCACTT 
AAAGTGCAGT CTAAGAAGCT TCCATGTCGA GGCCAGACTA CCTGCCGGGG ATCGTGTGAT 
TCTGGAGAGC TAAGCCGGAA CTCAGGAACA TTTTCTTCAC AGATTGAGAA TACACCTGTC 
TTGTGTCCTT TTCATTTGCA ACCAGTGCCT GAACCTGAGA CAGTGTTAAA AAATCAAGAA 
GTAGAATTTG GCAGAAATCG AGAGAGGCTT CAGTTTTTCA AGTGGAGCTC AGGAGCTTTT 
AAGAATGTGG CAGTCATCCC GCCTGGAACT GGAATGGCTC ATCAAGTGAA CTTAGAATAT 
TTATCAAGAG TAGTTTTTGA AGAAACGGAC CTGCTCTTCC CAGACAGTGT AGTTGGCACA 
GATTCTCATA TAACCATGGT GAACGGATTG GGGATTCTTG GGTGGGGAGT TGGTGGCATT 
GAGACAGAGG CAGTTATGCT TGGCCTGCCA GTTACTCTTA CTTTACCAGA GGTGGTTGGA 
TGTGAGCTAA CTGGGTCATC CAATGCTTTT GTTACATCCA TAGATATTGT CCTTGGCATT 
ACAAAGCACC TCAGGCAAGT AGGCGTGGCT GGAAAGTTTG TTGAGTTCTT TGGAAGTGGA 
GTTTCACAAT TATCTATTGT CGATAGAACT ACCATAGCAA ACATGTGTCC AGAATATGGT 
GCTATCCTCA GCTTTTTCCC TGTTGACAAT GTGACACTAC GACATTTAGA ACATACAGGT 
TTTGACAAAA CCAAACTTGA GTCAATGGAA AAATACCTTA AAGCTGTGAA ATTGTTTCGA 
AATGATGAGA ATTCTTCAGA ACCTGAATAT TCTCAGGTGA TACAGATTAA TCTGAATTCA 
ATAGTTGCAT CTGTCAGTGG TCCAAAAAGG CCTCAGGATA GGGTTGCTGT AACAGATATG 
AAAAGTGATT TTCAGGCTTG CTTAAATGAA AAGGTTGGAT TTAAAGGCTT CCAAGTTGCA 
GCAGAAAAAC AAAGTGACAC TGTCTCTGTT CGTTATGATG GAAGTGAGTA TAAGCTGTCC 
CATGGATCCG TGGTCATTGC TGCAGTTATC AGTTGTACCA ATAATTGCAA TCCATCTGTG 
ATGCTTGCTG CAGGTCTTCT GGCTAAAAAG GCTGTTGAAA TTGGTCTACG AGTTAAACCT 
TATATACGAA CAAGTTTGTC TCCAGGCAGT GGGATGGTTA CACATTACCT CAGTTCAAGT 
GGAGTGCTAC CCTATCTTAG CAAGCTAGGG TTTGACATAG TTGGCTATGG ATGTTCAACA 
TGTGTAGGAA ATACAGCACC TTTATCAGAA GCAGTTTTGA ATGCAGTAAA ACAGGGTGAT 
TTGGTTACCT GTGGAGTTTT ATCTGGAAAC AAACATTTCG AAGGCCGTCT CTGTGATTGT 
GTCCGTGCCA ATTATCTCGC CTCTCCGCCC TTAGTGGTGG CTTATGCCAT AGCAGGCACA 
GTGAATATAG ACTTCCAGAC AGAGCCTTTA GGTACTGACT CTACGGGCAA GGAAATTTAC 
CTGCATGACA TTTGGCCTAG TCGAGAAGAA GTTCATCAGA TGGAGGAAGA ACATGTTATA 
TTGTCAATGT TTAAAACACT AAAAGAGAAA GTAGAGATGG GAAATAAACG GTGGAATTCG 
TTAGAAGCTC CAGACTCCGT GCTGTTTCCA TGGGATGTGA AGTCTACTTA CATCAGATGC 
CCTTCATTTT TTGATAAGCT TGTAAGTACC AGTGTACTAC CAAAGAGCCA GCTGCATCCC 
AGCCTATTGA GAATGCCCAT GTCCTGTTGT ATTTGGGAGA CTCTGTCACT ACAGATCATA 
TATCACCCGC TGGAAGTATT GCTAGGAGTA GTGCTGCTGC TAAGTATTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.
The Journal of experimental medicine216(4)950-965(2019 Apr)
Muto Y,Moroishi T,Ichihara K,Nishiyama M,Shimizu H,Eguchi H,Moriya K,Koike K,Mimori K,Mori M,Katayama Y,Nakayama KI

Iron regulatory protein 2 deficiency may correlate with insulin resistance.
Biochemical and biophysical research communications510(2)191-197(2019 03)
Zhou Y,Wu W,Xu Z,Liu Y,Chang H,Yu P,Zhang X,Yang Y,Liu K,Chang Y

Leishmania donovani inhibits ferroportin translation by modulating FBXL5-IRP2 axis for its growth within host macrophages.
Cellular microbiology20(7)e12834(2018 07)
Das NK,Sandhya S,G VV,Kumar R,Singh AK,Bal SK,Kumari S,Mukhopadhyay CK

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.
Nature communications816114(2017 07)
Muto Y,Nishiyama M,Nita A,Moroishi T,Nakayama KI

FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.
Molecular and cellular biology37(8)(2017 04)
Yamauchi T,Nishiyama M,Moroishi T,Kawamura A,Nakayama KI

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Ireb2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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