Brinp1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Brinp1
Entrez Gene ID	56710
Full Name	bone morphogenic protein/retinoic acid inducible neural specific 1
Synonyms	BRINP,Dbc1,Dbccr1,Fam5a
General protein information	Preferred Names bone morphogenic protein/retinoic acid inducible neural specific 1 Names BMP/retinoic acid-inducible neural-specific protein 1 BMP/retinoic acid-inducible neural-specific protein (BRINP) deleted in bladder cancer chromosome region candidate 1 deleted in bladder cancer protein 1 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_019967.2	NP_064351.2	BMP/retinoic acid-inducible neural-specific protein 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	BRINP1	NP_055433.2
Bos taurus (cattle)	BRINP1	NP_001015669.1
Macaca mulatta (Rhesus monkey)	DBC1	XP_002800043.1
Danio rerio (zebrafish)	LOC100334375	XP_002662264.3
Mus musculus (house mouse)	Brinp1	NP_064351.2
Xenopus tropicalis (tropical clawed frog)	dbc1	XP_002935252.2
Pan troglodytes (chimpanzee)	DBC1	XP_520219.2
Canis lupus familiaris (dog)	BRINP1	XP_538815.2
Rattus norvegicus (Norway rat)	Brinp1	NP_536730.1
Gallus gallus (chicken)	BRINP1	NP_989780.1

Gene Ontology
Bibliography

Related articles in PubMed

Decreased parvalbumin and somatostatin neurons in medial prefrontal cortex in BRINP1-KO mice.
Kobayashi M, Hayashi Y, Fujimoto Y, Matsuoka I
Neuroscience letters68382-88(2018 09)

Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.
Berkowicz SR, Featherby TJ, Qu Z, Giousoh A, Borg NA, Heng JI, Whisstock JC, Bird PI
Molecular autism722(2016)

DBC1 functions as a tumor suppressor by regulating p53 stability.
Qin B, Minter-Dykhouse K, Yu J, Zhang J, Liu T, Zhang H, Lee S, Kim J, Wang L, Lou Z
Cell reports10(8)1324-34(2015 Mar)

Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles.
Chang H, Cahill H, Smallwood PM, Wang Y, Nathans J
PLoS genetics11(9)e1005532(2015)

DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity.
Kong S, Thiruppathi M, Qiu Q, Lin Z, Dong H, Chini EN, Prabhakar BS, Fang D
Journal of immunology (Baltimore, Md. : 1950)193(11)5515-24(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Brinp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Brinp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11839	NM_019967.2 Latest version!	Mus musculus bone morphogenic protein/retinoic acid inducible neural specific 1 (Brinp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$447.30 $639.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Brinp1 ( NM_019967.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064351.2 Mus musculus bone morphogenic protein/retinoic acid inducible neural specific 1 (Brinp1), mRNA.

Price & Availability↑

CloneID	OMu11839
Clone ID Related Accession (Same CDS sequence)	NM_019967.2
Accession Version	NM_019967.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2283bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	BMP/retinoic acid-inducible neural-specific protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB060589.1 and AK045420.1. On Jan 24, 2006 this sequence version replaced NM_019967.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK045420.1, SRR1660817.43994.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164136 [ECO:0000348] ##Evidence-Data-END##

ATGAACTGGA GGTTTGTTGA GCTCCTCTAC TTCCTGTTTG TATGGGGCCG TATCTCAGTG 
CAGCCCTCCC GCCAGGAGCC AGCTGGGACA GACCAACATG TCTCCAAGGA ATTTGATTGG 
CTTATTTCAG ACAGGGGGCC TTTCCACCAC TCCAGGAGCT ACCTATCCTT TGTGGAAAGA 
CACCGGCAAG GATTTACAAC CAGATATAAA ATATACAGGG AGTTTGCCCG TTGGAAGGTG 
AGGAACACAG CCATAGAAAG GAGAGACCTG GTCCGTCACC CAGTGCCCCT CATGCCGGAG 
TTTCAAAGGA GCATCCGTCT GCTTGGCAGG AGACCCACCA CTCAGCAGTT CATTGATACC 
ATCATCAAAA AGTACGGCAC CCACCTGCTC ATCTCTGCTA CATTGGGAGG AGAGGAGGCT 
TTGACCATGT ACATGGACAA AAGTCGCCTG GACCGGAAGT CAGGGAATGC TACCCAAAGT 
GTTGAAGCTT TGCACCAGCT TGCATCATCC TACTTTGTCG ACCGTGATGG CACCATGAGA 
AGGCTCCATG AGATCCAGAT TTCAACTGGA GCAATCAAGG TCACAGAAAC ACGCACTGGG 
CCTCTGGGCT GTAACAGCTA TGACAATCTG GACTCTGTGA GTTCTGTCCT TCTGCAAAGC 
ACGGAGAGCA AACTGCACCT TCAAGGTCTT CAGATAATCT TCCCGCAGTA TCTGCAAGAG 
AAGTTTGTTC AGTCGGCCTT GAGTTACATC ATGTGCAATG GAGAGGGAGA GTATGTGTGT 
CAGAACAGCC AGTGTCGCTG CCAGTGTGCT GAGGAGTTCC CACAGTGCAA CTGCCCCATC 
ACCGACATCC AGATCATGGA GTTTACGCTG GCAAACATGG CCAAGGCCTG GACTGAAGCT 
TATAAGGACC TGGAGAATTC AGATGAGTTT AAGTCATTTA TGAAGCGTCT CCCAAGCAAC 
CACTTCCTGA CGATTGGCAG CATCCACCAG CACTGGGGCA ATGACTGGGA CCTGCAGAGC 
CGTTACAAGC TCCTACAGAG TGCCACTGAG GCTCAGAGGC AGAAAATCCA GAGGACCGCC 
CGCAAGCTCT TTGGCCTCAG TGTGCGCTGC CGCCACAATC CCAACCACCA GCTGCCTAGA 
GAGAGGACAA TTCAACAGTG GCTTGCAAGG GTCCAGTCAC TTCTCTATTG CAATGAGAAT 
GGGTTCTGGG GAACCTTCCT GGAAAGCCAG AGGAGTTGTG TGTGCCATGG TAGCACCACA 
CTGTGCCAGC GCCCTATCCC ATGTATCATA GGTGGGAACA ACAGCTGTGC CATGTGCAGC 
CTGGCCAACA TCTCACTCTG TGGCTCCTGC AATAAGGGCT ACAAGCTGTA TAGAGGCCGC 
TGTGAACCAC AAAACGTGGA CTCTGAGCGG AGTGAGCAGT TCATCAGCTT TGAGACCGAC 
CTGGACTTCC AGGACTTGGA ACTGAAGTAC CTGTTGCAGA AGATGGATTC ACGCCTCTAT 
GTCCATACTA CCTTCATCAG CAATGAGATT CGCCTGGATA CATTTTTTGA CCCTCGGTGG 
CGCAAGCGCA TGTCCCTCAC TCTCAAAAGC AACAAGAACC GCATGGACTT TATCCACATG 
GTGATCGGAA TGTCCATGCG TATCTGCCAG ATGCGCAACA GCAGCCTGGA CCCTATGTTC 
TTTGTCTATG TCAATCCCTT CAGTGGGAGC CATTCAGAAG GCTGGAACAT GCCCTTTGGG 
GAATTTGGCT ACCCTCGTTG GGAGAAGATC CGTCTGCAAA ACAGCCAATG CTACAATTGG 
ACTCTCTTGC TGGGCAATCG GTGGAAAACT TTTTTCGAGA CTGTCCATAT CTACCTACGT 
AGTCGGACTC GGCTACCCAC CCTACGCAAT GAGACTGGCC AGGGCCCGGT GGACCTGTCG 
GATCCCTCCA AAAGGCAGTT CTACATCAAG ATCTCTGATG TACAGGTGTT TGGGTACAGC 
CTGAGGTTCA ATGCTGACCT CCTACGAAGT GCCGTGCAAC AGGTGAATCA GTCCTATACA 
CAGGGTGGTC AGTTCTATTC CTCCTCATCC GTGATGCTTC TCATGTTGGA CATTCGGGAC 
CGAATCAACC GCCTGGCCCC TCCTGTGGCC CCAGGAAAAC CCCAGCTGGA CTTGTTTTCC 
TGTATGCTGA AGCACCGCCT GAAGCTGACC AACAGTGAGA TTATCAGGGT GAACCATGCC 
TTGGACCTCT ACAACACTGA GATCCTCAAA CAGTCTGACC AGATGACAGC CAAACTCTGC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064351.2
CDS	435..2717
Translation	MNWRFVELLYFLFVWGRISVQPSRQEPAGTDQHVSKEFDWLISDRGPFHHSRSYLSFVERHRQGFTTRYKIYREFARWKVRNTAIERRDLVRHPVPLMPEFQRSIRLLGRRPTTQQFIDTIIKKYGTHLLISATLGGEEALTMYMDKSRLDRKSGNATQSVEALHQLASSYFVDRDGTMRRLHEIQISTGAIKVTETRTGPLGCNSYDNLDSVSSVLLQSTESKLHLQGLQIIFPQYLQEKFVQSALSYIMCNGEGEYVCQNSQCRCQCAEEFPQCNCPITDIQIMEFTLANMAKAWTEAYKDLENSDEFKSFMKRLPSNHFLTIGSIHQHWGNDWDLQSRYKLLQSATEAQRQKIQRTARKLFGLSVRCRHNPNHQLPRERTIQQWLARVQSLLYCNENGFWGTFLESQRSCVCHGSTTLCQRPIPCIIGGNNSCAMCSLANISLCGSCNKGYKLYRGRCEPQNVDSERSEQFISFETDLDFQDLELKYLLQKMDSRLYVHTTFISNEIRLDTFFDPRWRKRMSLTLKSNKNRMDFIHMVIGMSMRICQMRNSSLDPMFFVYVNPFSGSHSEGWNMPFGEFGYPRWEKIRLQNSQCYNWTLLLGNRWKTFFETVHIYLRSRTRLPTLRNETGQGPVDLSDPSKRQFYIKISDVQVFGYSLRFNADLLRSAVQQVNQSYTQGGQFYSSSSVMLLMLDIRDRINRLAPPVAPGKPQLDLFSCMLKHRLKLTNSEIIRVNHALDLYNTEILKQSDQMTAKLC

Target ORF information:

RefSeq Version	NM_019967.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus bone morphogenic protein/retinoic acid inducible neural specific 1 (Brinp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019967.2

ORF Insert Sequence:

ATGAACTGGA GGTTTGTTGA GCTCCTCTAC TTCCTGTTTG TATGGGGCCG TATCTCAGTG 
CAGCCCTCCC GCCAGGAGCC AGCTGGGACA GACCAACATG TCTCCAAGGA ATTTGATTGG 
CTTATTTCAG ACAGGGGGCC TTTCCACCAC TCCAGGAGCT ACCTATCCTT TGTGGAAAGA 
CACCGGCAAG GATTTACAAC CAGATATAAA ATATACAGGG AGTTTGCCCG TTGGAAGGTG 
AGGAACACAG CCATAGAAAG GAGAGACCTG GTCCGTCACC CAGTGCCCCT CATGCCGGAG 
TTTCAAAGGA GCATCCGTCT GCTTGGCAGG AGACCCACCA CTCAGCAGTT CATTGATACC 
ATCATCAAAA AGTACGGCAC CCACCTGCTC ATCTCTGCTA CATTGGGAGG AGAGGAGGCT 
TTGACCATGT ACATGGACAA AAGTCGCCTG GACCGGAAGT CAGGGAATGC TACCCAAAGT 
GTTGAAGCTT TGCACCAGCT TGCATCATCC TACTTTGTCG ACCGTGATGG CACCATGAGA 
AGGCTCCATG AGATCCAGAT TTCAACTGGA GCAATCAAGG TCACAGAAAC ACGCACTGGG 
CCTCTGGGCT GTAACAGCTA TGACAATCTG GACTCTGTGA GTTCTGTCCT TCTGCAAAGC 
ACGGAGAGCA AACTGCACCT TCAAGGTCTT CAGATAATCT TCCCGCAGTA TCTGCAAGAG 
AAGTTTGTTC AGTCGGCCTT GAGTTACATC ATGTGCAATG GAGAGGGAGA GTATGTGTGT 
CAGAACAGCC AGTGTCGCTG CCAGTGTGCT GAGGAGTTCC CACAGTGCAA CTGCCCCATC 
ACCGACATCC AGATCATGGA GTTTACGCTG GCAAACATGG CCAAGGCCTG GACTGAAGCT 
TATAAGGACC TGGAGAATTC AGATGAGTTT AAGTCATTTA TGAAGCGTCT CCCAAGCAAC 
CACTTCCTGA CGATTGGCAG CATCCACCAG CACTGGGGCA ATGACTGGGA CCTGCAGAGC 
CGTTACAAGC TCCTACAGAG TGCCACTGAG GCTCAGAGGC AGAAAATCCA GAGGACCGCC 
CGCAAGCTCT TTGGCCTCAG TGTGCGCTGC CGCCACAATC CCAACCACCA GCTGCCTAGA 
GAGAGGACAA TTCAACAGTG GCTTGCAAGG GTCCAGTCAC TTCTCTATTG CAATGAGAAT 
GGGTTCTGGG GAACCTTCCT GGAAAGCCAG AGGAGTTGTG TGTGCCATGG TAGCACCACA 
CTGTGCCAGC GCCCTATCCC ATGTATCATA GGTGGGAACA ACAGCTGTGC CATGTGCAGC 
CTGGCCAACA TCTCACTCTG TGGCTCCTGC AATAAGGGCT ACAAGCTGTA TAGAGGCCGC 
TGTGAACCAC AAAACGTGGA CTCTGAGCGG AGTGAGCAGT TCATCAGCTT TGAGACCGAC 
CTGGACTTCC AGGACTTGGA ACTGAAGTAC CTGTTGCAGA AGATGGATTC ACGCCTCTAT 
GTCCATACTA CCTTCATCAG CAATGAGATT CGCCTGGATA CATTTTTTGA CCCTCGGTGG 
CGCAAGCGCA TGTCCCTCAC TCTCAAAAGC AACAAGAACC GCATGGACTT TATCCACATG 
GTGATCGGAA TGTCCATGCG TATCTGCCAG ATGCGCAACA GCAGCCTGGA CCCTATGTTC 
TTTGTCTATG TCAATCCCTT CAGTGGGAGC CATTCAGAAG GCTGGAACAT GCCCTTTGGG 
GAATTTGGCT ACCCTCGTTG GGAGAAGATC CGTCTGCAAA ACAGCCAATG CTACAATTGG 
ACTCTCTTGC TGGGCAATCG GTGGAAAACT TTTTTCGAGA CTGTCCATAT CTACCTACGT 
AGTCGGACTC GGCTACCCAC CCTACGCAAT GAGACTGGCC AGGGCCCGGT GGACCTGTCG 
GATCCCTCCA AAAGGCAGTT CTACATCAAG ATCTCTGATG TACAGGTGTT TGGGTACAGC 
CTGAGGTTCA ATGCTGACCT CCTACGAAGT GCCGTGCAAC AGGTGAATCA GTCCTATACA 
CAGGGTGGTC AGTTCTATTC CTCCTCATCC GTGATGCTTC TCATGTTGGA CATTCGGGAC 
CGAATCAACC GCCTGGCCCC TCCTGTGGCC CCAGGAAAAC CCCAGCTGGA CTTGTTTTCC 
TGTATGCTGA AGCACCGCCT GAAGCTGACC AACAGTGAGA TTATCAGGGT GAACCATGCC 
TTGGACCTCT ACAACACTGA GATCCTCAAA CAGTCTGACC AGATGACAGC CAAACTCTGC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Decreased parvalbumin and somatostatin neurons in medial prefrontal cortex in BRINP1-KO mice.
Neuroscience letters68382-88(2018 09)
Kobayashi M,Hayashi Y,Fujimoto Y,Matsuoka I

Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.
Molecular autism722(2016)
Berkowicz SR,Featherby TJ,Qu Z,Giousoh A,Borg NA,Heng JI,Whisstock JC,Bird PI

DBC1 functions as a tumor suppressor by regulating p53 stability.
Cell reports10(8)1324-34(2015 Mar)
Qin B,Minter-Dykhouse K,Yu J,Zhang J,Liu T,Zhang H,Lee S,Kim J,Wang L,Lou Z

Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles.
PLoS genetics11(9)e1005532(2015)
Chang H,Cahill H,Smallwood PM,Wang Y,Nathans J

DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity.
Journal of immunology (Baltimore, Md. : 1950)193(11)5515-24(2014 Dec)
Kong S,Thiruppathi M,Qiu Q,Lin Z,Dong H,Chini EN,Prabhakar BS,Fang D

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Brinp1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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