Arl2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arl2
Entrez Gene ID	56327
Full Name	ADP-ribosylation factor-like 2
Synonyms	2610009M23Rik,AI115441,AW553335
General protein information	Preferred Names ADP-ribosylation factor-like 2 Names ADP-ribosylation factor-like protein 2 ADP-ribosylation-like 2 arf-like protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 A

mRNA and Protein(s)

mRNA	Protein	Name
NM_019722.3	NP_062696.2	ADP-ribosylation factor-like protein 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ARL2	NP_001033168.1
Rattus norvegicus (Norway rat)	Arl2	NP_113899.1
Danio rerio (zebrafish)	arl2	NP_001005947.1
Drosophila melanogaster (fruit fly)	Arf84F	NP_476886.1
Pan troglodytes (chimpanzee)	ARL2	XP_003951973.1
Homo sapiens (human)	ARL2	NP_001658.2
Mus musculus (house mouse)	Arl2	NP_062696.2
Oryza sativa (rice)	Os02g0327100	NP_001046710.1
Neurospora crassa	NCU00218	XP_956603.2
Caenorhabditis elegans (roundworm)	evl-20	NP_495779.1
Xenopus tropicalis (tropical clawed frog)	arl2	NP_989148.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005267	XP_309056.3
Canis lupus familiaris (dog)	ARL2	XP_540874.2
Arabidopsis thaliana (thale cress)	TTN5	NP_179430.1
Schizosaccharomyces pombe (fission yeast)	alp41	NP_593036.1

Gene Ontology
Bibliography

Related articles in PubMed

Whole-exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome.
Cai XB, Wu KC, Zhang X, Lv JN, Jin GH, Xiang L, Chen J, Huang XF, Pan D, Lu B, Lu F, Qu J, Jin ZB
Clinical genetics96(1)61-71(2019 Jul)

The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors.
Newman LE, Schiavon CR, Zhou C, Kahn RA
PloS one12(4)e0175164(2017)

PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.
Fansa EK, Kösling SK, Zent E, Wittinghofer A, Ismail S
Nature communications711366(2016 Apr)

The Function of Arf-like Proteins ARL2 and ARL3 in Photoreceptors.
Hanke-Gogokhia C, Zhang H, Frederick JM, Baehr W
Advances in experimental medicine and biology854655-61(2016)

The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
Lokaj M, Kösling SK, Koerner C, Lange SM, van Beersum SE, van Reeuwijk J, Roepman R, Horn N, Ueffing M, Boldt K, Wittinghofer A
Structure (London, England : 1993)23(11)2122-32(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Arl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21769	NM_019722.3 Latest version!	Mus musculus ADP-ribosylation factor-like 2 (Arl2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arl2 ( NM_019722.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062696.2 Mus musculus ADP-ribosylation factor-like 2 (Arl2), mRNA.

Price & Availability↑

CloneID	OMu21769
Clone ID Related Accession (Same CDS sequence)	NM_019722.3
Accession Version	NM_019722.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575820800000
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK011366.1. On Jun 20, 2003 this sequence version replaced NM_019722.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK011366.1, BC060259.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCTTC TGACCATTCT GAAGAAGATG AAGCAGAAAG AGCGAGAGCT GCGGCTGCTC 
ATGCTTGGCT TGGACAACGC TGGCAAAACA ACCATCCTCA AGAAGTTCAA TGGAGAAGAC 
GTGGACACCA TCTCCCCGAC ACTGGGCTTC AACATCAAGA CCCTGGAGCA CCGCGGATTC 
AAGCTGAACA TCTGGGATGT AGGTGGCCAG AAGTCTCTGC GCTCCTACTG GAGGAACTAC 
TTTGAGAGCA CGGATGGCCT CATCTGGGTG GTGGACAGCG CCGACCGCCA GCGCATGCAG 
GACTGTCAGC GAGAGCTGCA GAGCCTACTG GTGGAGGAGC GCCTGGCTGG AGCAACCCTC 
CTCATCTTTG CCAACAAGCA GGACCTGCCT GGAGCACTGT CCTGTAATGC TATTCAGGAG 
GCCCTGGAGC TGGACTCCAT CCGCAGCCAC CACTGGCGCA TCCAGGGCTG CAGTGCTGTC 
ACAGGGGAAG ACCTGCTGCC TGGCATCGAC TGGCTCCTTG ATGACATTTC CAGTCGTGTC 
TTTACTGCCG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062696.2
CDS	37..591
Translation	MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDVDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATLLIFANKQDLPGALSCNAIQEALELDSIRSHHWRIQGCSAVTGEDLLPGIDWLLDDISSRVFTAD

Target ORF information:

RefSeq Version	NM_019722.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 2 (Arl2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019722.3

ORF Insert Sequence:

ATGGGGCTTC TGACCATTCT GAAGAAGATG AAGCAGAAAG AGCGAGAGCT GCGGCTGCTC 
ATGCTTGGCT TGGACAACGC TGGCAAAACA ACCATCCTCA AGAAGTTCAA TGGAGAAGAC 
GTGGACACCA TCTCCCCGAC ACTGGGCTTC AACATCAAGA CCCTGGAGCA CCGCGGATTC 
AAGCTGAACA TCTGGGATGT AGGTGGCCAG AAGTCTCTGC GCTCCTACTG GAGGAACTAC 
TTTGAGAGCA CGGATGGCCT CATCTGGGTG GTGGACAGCG CCGACCGCCA GCGCATGCAG 
GACTGTCAGC GAGAGCTGCA GAGCCTACTG GTGGAGGAGC GCCTGGCTGG AGCAACCCTC 
CTCATCTTTG CCAACAAGCA GGACCTGCCT GGAGCACTGT CCTGTAATGC TATTCAGGAG 
GCCCTGGAGC TGGACTCCAT CCGCAGCCAC CACTGGCGCA TCCAGGGCTG CAGTGCTGTC 
ACAGGGGAAG ACCTGCTGCC TGGCATCGAC TGGCTCCTTG ATGACATTTC CAGTCGTGTC 
TTTACTGCCG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Whole-exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome.
Clinical genetics96(1)61-71(2019 Jul)
Cai XB,Wu KC,Zhang X,Lv JN,Jin GH,Xiang L,Chen J,Huang XF,Pan D,Lu B,Lu F,Qu J,Jin ZB

The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors.
PloS one12(4)e0175164(2017)
Newman LE,Schiavon CR,Zhou C,Kahn RA

PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.
Nature communications711366(2016 Apr)
Fansa EK,Kösling SK,Zent E,Wittinghofer A,Ismail S

The Function of Arf-like Proteins ARL2 and ARL3 in Photoreceptors.
Advances in experimental medicine and biology854655-61(2016)
Hanke-Gogokhia C,Zhang H,Frederick JM,Baehr W

The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
Structure (London, England : 1993)23(11)2122-32(2015 Nov)
Lokaj M,Kösling SK,Koerner C,Lange SM,van Beersum SE,van Reeuwijk J,Roepman R,Horn N,Ueffing M,Boldt K,Wittinghofer A

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Arl2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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