Nupr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nupr1
Entrez Gene ID	56312
Full Name	nuclear protein transcription regulator 1
Synonyms	2310032H04Rik,Com1,p8
General protein information	Preferred Names nuclear protein transcription regulator 1 Names nuclear protein 1 nuclear transcriptional regulator protein 1 protein p8
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F3

mRNA and Protein(s)

mRNA	Protein	Name
NM_019738.1	NP_062712.1	nuclear protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	NUPR1	NP_036517.1
Rattus norvegicus (Norway rat)	P8	XP_006230263.1
Rattus norvegicus (Norway rat)	Nupr1	NP_446063.1
Bos taurus (cattle)	NUPR1	NP_001107987.1
Canis lupus familiaris (dog)	NUPR1	XP_536921.2
Mus musculus (house mouse)	Nupr1	NP_062712.1

Gene Ontology
Bibliography

Related articles in PubMed

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis.
Santofimia-Castaño P, Lan W, Bintz J, Gayet O, Carrier A, Lomberk G, Neira JL, González A, Urrutia R, Soubeyran P, Iovanna J
Scientific reports8(1)16999(2018 11)

TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme.
Aydoğdu N, Rudat C, Trowe MO, Kaiser M, Lüdtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A
Development (Cambridge, England)145(23)(2018 11)

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.
Kasowitz SD, Ma J, Anderson SJ, Leu NA, Xu Y, Gregory BD, Schultz RM, Wang PJ
PLoS genetics14(5)e1007412(2018 05)

p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet.
Hollenbach M, Klöting N, Sommerer I, Lorenz J, Heindl M, Kern M, Mössner J, Blüher M, Hoffmeister A
PloS one13(7)e0201159(2018)

Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke.
Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE
Stroke47(12)3022-3031(2016 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nupr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nupr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21931	NM_019738.1 Latest version!	Mus musculus nuclear protein transcription regulator 1 (Nupr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nupr1 ( NM_019738.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062712.1 Mus musculus nuclear protein transcription regulator 1 (Nupr1), mRNA.

Price & Availability↑

CloneID	OMu21931
Clone ID Related Accession (Same CDS sequence)	NM_019738.1
Accession Version	NM_019738.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 243bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	nuclear protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF131196.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF131196.1, BC002109.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCCACCT TGCCACCAAC AGCCAACCCT TCCCAGCAAC CTCTAAACCT AGAGGATGAA 
GATGGAATCC TGGATGAATA TGATCAGTAC AGCCTGGCCC ATCCCTGTGT CGTCGGGGGA 
GGTCGGAAAG GTCGGACCAA GAGAGAAGCT GCTGCCAATA CCAACCGCCC TAGCCCTGGC 
GGGCATGAGA GGAAGCTGCT GACCAAGTTC CAGAACTCTG AAAGGAAAAA AGCCTGGCGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062712.1
CDS	37..279
Translation	MATLPPTANPSQQPLNLEDEDGILDEYDQYSLAHPCVVGGGRKGRTKREAAANTNRPSPGGHERKLLTKFQNSERKKAWR

Target ORF information:

RefSeq Version	NM_019738.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus nuclear protein transcription regulator 1 (Nupr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019738.1

ORF Insert Sequence:

ATGGCCACCT TGCCACCAAC AGCCAACCCT TCCCAGCAAC CTCTAAACCT AGAGGATGAA 
GATGGAATCC TGGATGAATA TGATCAGTAC AGCCTGGCCC ATCCCTGTGT CGTCGGGGGA 
GGTCGGAAAG GTCGGACCAA GAGAGAAGCT GCTGCCAATA CCAACCGCCC TAGCCCTGGC 
GGGCATGAGA GGAAGCTGCT GACCAAGTTC CAGAACTCTG AAAGGAAAAA AGCCTGGCGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis.
Scientific reports8(1)16999(2018 11)
Santofimia-Castaño P,Lan W,Bintz J,Gayet O,Carrier A,Lomberk G,Neira JL,González A,Urrutia R,Soubeyran P,Iovanna J

TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme.
Development (Cambridge, England)145(23)(2018 11)
Aydoğdu N,Rudat C,Trowe MO,Kaiser M,Lüdtke TH,Taketo MM,Christoffels VM,Moon A,Kispert A

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.
PLoS genetics14(5)e1007412(2018 05)
Kasowitz SD,Ma J,Anderson SJ,Leu NA,Xu Y,Gregory BD,Schultz RM,Wang PJ

p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet.
PloS one13(7)e0201159(2018)
Hollenbach M,Klöting N,Sommerer I,Lorenz J,Heindl M,Kern M,Mössner J,Blüher M,Hoffmeister A

Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke.
Stroke47(12)3022-3031(2016 12)
Lucitti JL,Sealock R,Buckley BK,Zhang H,Xiao L,Dudley AC,Faber JE