| Gene Symbol | Jph4 |
| Entrez Gene ID | 319984 |
| Full Name | junctophilin 4 |
| Synonyms | 9330157P13Rik,JP-4,JPHL1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Jph4 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Jph4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jph4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu05878 Clone ID Related Accession (Same CDS sequence) NM_177049.5 Accession Version NM_177049.5 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1887bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577376000000 Organism Mus musculus(house mouse) Product junctophilin-4 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC157212.2 and AB099712.1. On Mar 25, 2011 this sequence version replaced NM_177049.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY341261.1, BC052376.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861ATGTCCCCCG GGGGCAAGTT CGACTTTGAC GACGGGGGCT GCTACGTGGG GGGCTGGGAG
GCGGGGCGGG CACATGGCTA CGGCGTGTGC ACCGGGCCCG GCGCCCAGGG AGAGTACAGC
GGCTGCTGGG CTCACGGCTT CGAGTCGCTG GGTGTCTTCA CGGGGCCCGG CGGACACAGT
TACCAGGGCC ACTGGCAGCA GGGCAAGCGC GAAGGGCTGG GCGTGGAGCG CAAGAGCCGC
TGGACCTACC GCGGCGAGTG GCTGGGCGGG CTGAAGGGGC GCAGCGGCGT ATGGGAGAGC
GTGTCCGGCC TGCGCTACGC CGGGCTCTGG AAGGACGGCT TCCAGGACGG CTACGGCACC
GAGACCTACT CGGATGGAGG CACTTACCAA GGCCAGTGGC AAGCCGGGAA ACGCCACGGC
TACGGGGTGC GCCAAAGTGT ACCCTACCAC CAGGCGGCGC TTCTGCGCTC ACCCCGCCGC
ACCTCCCTGG ACTCCGGCCA CAGCGACCCC CCGACGCCGC CTCCACCCCT ACCCCTACCA
GGAGATGAAG GAGGCAGCCC AGCCTCCGGC TCCCGAGGCG GCTTCGTGCT GGCGGGGCCA
GGGGACGCCG ACGGGGCGTC TTCCCGTAAG CGCACCCCAG CAGCAGGTGG ATTCTTCCGC
CGTTCACTGC TGCTCAGCGG GCTCCGGGCT GGTGGGCGCC GCAGCTCCCT GGGCAGCAAG
AGGGGATCTC TACGCAGCGA GGTGAGCAGC GAAGTGGGCA GTACAGGACC CCCGGGCTCC
GAGGCCAGCG GGCCCCCAAT CCCAGCTCCA CCTGCCCTCA TCGAGGGCTC AGCCACTGAG
GTGTACGCCG GTGAGTGGCG TGCGGACCGG CGCAGTGGCT ATGGAGTGAG CCAGAGATCC
AACGGGCTGC GCTACGAAGG CGAGTGGCTG GGCAACCGAC GCCACGGATA CGGGCGCACC
ACCCGGCCCG ATGGCTCCCG TGAGGAGGGC AAGTACAAGC GTAACCGGCT GGTACACGGG
GGACGTGTCC GCAGCCTCCT GCCTCTGGCC CTTAGACGGG GCAAAGTCAA GGAGAAAGTG
GACAGGGCTG TCGAAGGTGC CCGTCGAGCT GTGAGTGCTG CCCGCCAGCG CCAGGAAATT
GCGGCTGCCA GGGCAGCAGA CGCCCTCCTA AAAGCAGTGG CAGCCAGCAG CGTCGCGGAG
AAGGCTGTGG AGGCTGCGCG GATGGCCAAG CTGATAGCCC AGGATCTACA ACCCATGTTA
GAGGCCCCAG GCCGCAGACC CAGACAGGAC TCAGGAGGTT CTGACACAGA GCCTTTGGAT
GAGGACAGCC CTGGGGTATA CGAGAATGGA CTGACCCCCT CAGAGGGCTC TCCGGAACTA
CCCAGCAGCC CCGCCTCCTC CCACCAACCT TGGCGAGCCC CTGCCTGCCG GAGTCCACTG
CCTCCTGGAG GGAACTGGGG CCCCTTCTCC AGCCCTAAAG CTTGGCCCGA GGAGTGGGGG
GGTCCTGGTG AGCAGGCAGA GGAACTAGCT GGCTATGAGG CTGAGGATGA GGCTGGGGTG
CAGGGTCCAG GACCAAGAGA TGGTTCCCCA CTTCTCGGAG GCTGCAGTGA CAGTTCAGGA
AGTCTTCGAG AGGAGGAGGG GGAAGACGAA GAGTCCTTGC CCCAACTGAG GGCCCCAGGA
GGCTCAGAGT CTGAGCCTGT CACCACGCCA GTTTTGAGGG GCCTGTCTTC AAGGGGTCCT
GATGCTGGGT GCCTGACAGA AGAGGTTGAG GAGCCTGCTC CCACCGAGAG GCCTGCCCAG
CCGGGAGCTG CCAACCCCCT GGTGGTGGGA GCCGTGGCCT TGCTGGACCT CAGCCTGGCC
TTCCTGTTCT CCCAGCTCCT CACCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_796023.2 CDS 1117..3003 Translation 
Target ORF information:
RefSeq Version NM_177049.5 Organism Mus musculus(house mouse) Definition Mus musculus junctophilin 4 (Jph4), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_177049.5
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861ATGTCCCCCG GGGGCAAGTT CGACTTTGAC GACGGGGGCT GCTACGTGGG GGGCTGGGAG
GCGGGGCGGG CACATGGCTA CGGCGTGTGC ACCGGGCCCG GCGCCCAGGG AGAGTACAGC
GGCTGCTGGG CTCACGGCTT CGAGTCGCTG GGTGTCTTCA CGGGGCCCGG CGGACACAGT
TACCAGGGCC ACTGGCAGCA GGGCAAGCGC GAAGGGCTGG GCGTGGAGCG CAAGAGCCGC
TGGACCTACC GCGGCGAGTG GCTGGGCGGG CTGAAGGGGC GCAGCGGCGT ATGGGAGAGC
GTGTCCGGCC TGCGCTACGC CGGGCTCTGG AAGGACGGCT TCCAGGACGG CTACGGCACC
GAGACCTACT CGGATGGAGG CACTTACCAA GGCCAGTGGC AAGCCGGGAA ACGCCACGGC
TACGGGGTGC GCCAAAGTGT ACCCTACCAC CAGGCGGCGC TTCTGCGCTC ACCCCGCCGC
ACCTCCCTGG ACTCCGGCCA CAGCGACCCC CCGACGCCGC CTCCACCCCT ACCCCTACCA
GGAGATGAAG GAGGCAGCCC AGCCTCCGGC TCCCGAGGCG GCTTCGTGCT GGCGGGGCCA
GGGGACGCCG ACGGGGCGTC TTCCCGTAAG CGCACCCCAG CAGCAGGTGG ATTCTTCCGC
CGTTCACTGC TGCTCAGCGG GCTCCGGGCT GGTGGGCGCC GCAGCTCCCT GGGCAGCAAG
AGGGGATCTC TACGCAGCGA GGTGAGCAGC GAAGTGGGCA GTACAGGACC CCCGGGCTCC
GAGGCCAGCG GGCCCCCAAT CCCAGCTCCA CCTGCCCTCA TCGAGGGCTC AGCCACTGAG
GTGTACGCCG GTGAGTGGCG TGCGGACCGG CGCAGTGGCT ATGGAGTGAG CCAGAGATCC
AACGGGCTGC GCTACGAAGG CGAGTGGCTG GGCAACCGAC GCCACGGATA CGGGCGCACC
ACCCGGCCCG ATGGCTCCCG TGAGGAGGGC AAGTACAAGC GTAACCGGCT GGTACACGGG
GGACGTGTCC GCAGCCTCCT GCCTCTGGCC CTTAGACGGG GCAAAGTCAA GGAGAAAGTG
GACAGGGCTG TCGAAGGTGC CCGTCGAGCT GTGAGTGCTG CCCGCCAGCG CCAGGAAATT
GCGGCTGCCA GGGCAGCAGA CGCCCTCCTA AAAGCAGTGG CAGCCAGCAG CGTCGCGGAG
AAGGCTGTGG AGGCTGCGCG GATGGCCAAG CTGATAGCCC AGGATCTACA ACCCATGTTA
GAGGCCCCAG GCCGCAGACC CAGACAGGAC TCAGGAGGTT CTGACACAGA GCCTTTGGAT
GAGGACAGCC CTGGGGTATA CGAGAATGGA CTGACCCCCT CAGAGGGCTC TCCGGAACTA
CCCAGCAGCC CCGCCTCCTC CCACCAACCT TGGCGAGCCC CTGCCTGCCG GAGTCCACTG
CCTCCTGGAG GGAACTGGGG CCCCTTCTCC AGCCCTAAAG CTTGGCCCGA GGAGTGGGGG
GGTCCTGGTG AGCAGGCAGA GGAACTAGCT GGCTATGAGG CTGAGGATGA GGCTGGGGTG
CAGGGTCCAG GACCAAGAGA TGGTTCCCCA CTTCTCGGAG GCTGCAGTGA CAGTTCAGGA
AGTCTTCGAG AGGAGGAGGG GGAAGACGAA GAGTCCTTGC CCCAACTGAG GGCCCCAGGA
GGCTCAGAGT CTGAGCCTGT CACCACGCCA GTTTTGAGGG GCCTGTCTTC AAGGGGTCCT
GATGCTGGGT GCCTGACAGA AGAGGTTGAG GAGCCTGCTC CCACCGAGAG GCCTGCCCAG
CCGGGAGCTG CCAACCCCCT GGTGGTGGGA GCCGTGGCCT TGCTGGACCT CAGCCTGGCC
TTCCTGTTCT CCCAGCTCCT CACCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Junctophilin-4, a component of the endoplasmic reticulum-plasma membrane junctions, regulates Ca2+ dynamics in T cells.
Proceedings of the National Academy of Sciences of the United States of America113(10)2762-7(2016 Mar)
Woo JS,Srikanth S,Nishi M,Ping P,Takeshima H,Gwack Y
High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies.
PloS one6(9)e25181(2011)
Quillé ML,Carat S,Quéméner-Redon S,Hirchaud E,Baron D,Benech C,Guihot J,Placet M,Mignen O,Férec C,Houlgatte R,Friocourt G
Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins.
Biochemical and biophysical research communications363(3)835-9(2007 Nov)
Ikeda A,Miyazaki T,Kakizawa S,Okuno Y,Tsuchiya S,Myomoto A,Saito SY,Yamamoto T,Yamazaki T,Iino M,Tsujimoto G,Watanabe M,Takeshima H
Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.
The EMBO journal26(7)1924-33(2007 Apr)
Kakizawa S,Kishimoto Y,Hashimoto K,Miyazaki T,Furutani K,Shimizu H,Fukaya M,Nishi M,Sakagami H,Ikeda A,Kondo H,Kano M,Watanabe M,Iino M,Takeshima H
Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins.
Proceedings of the National Academy of Sciences of the United States of America103(28)10811-6(2006 Jul)
Moriguchi S,Nishi M,Komazaki S,Sakagami H,Miyazaki T,Masumiya H,Saito SY,Watanabe M,Kondo H,Yawo H,Fukunaga K,Takeshima H
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