Vps26a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vps26a
Entrez Gene ID	30930
Full Name	VPS26 retromer complex component A
Synonyms	AA407240,HB58,Vps26
General protein information	Preferred Names VPS26 retromer complex component A Names vacuolar protein sorting-associated protein 26A H beta 58 h58 protein mVPS26 vacuolar protein sorting 26 homolog A vacuole protein sorting 26 vesicle protein sorting 26A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 B4

mRNA and Protein(s)

mRNA	Protein	Name
NM_133672.3	NP_598433.1	vacuolar protein sorting-associated protein 26A isoform a
NM_001113355.1	NP_001106826.1	vacuolar protein sorting-associated protein 26A isoform b
XM_006513734.3	XP_006513797.1	vacuolar protein sorting-associated protein 26A isoform X1
NM_001358543.1	NP_001345472.1	vacuolar protein sorting-associated protein 26A isoform c

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os11g0629200	NP_001068312.1
Homo sapiens (human)	VPS26A	NP_004887.2
Pan troglodytes (chimpanzee)	VPS26A	XP_003312639.1
Macaca mulatta (Rhesus monkey)	VPS26A	XP_001108781.1
Canis lupus familiaris (dog)	VPS26A	XP_005619021.1
Rattus norvegicus (Norway rat)	Vps26a	NP_001007741.1
Gallus gallus (chicken)	VPS26A	XP_421577.2
Danio rerio (zebrafish)	vps26a	NP_957201.1
Mus musculus (house mouse)	Vps26a	NP_001106826.1
Arabidopsis thaliana (thale cress)	VPS26B	NP_194499.2
Oryza sativa (rice)	Os12g0500700	NP_001066819.1
Bos taurus (cattle)	VPS26A	NP_001068923.1
Arabidopsis thaliana (thale cress)	VPS26A	NP_200165.1
Xenopus tropicalis (tropical clawed frog)	vps26a	NP_001017171.1

Gene Ontology
Bibliography

Related articles in PubMed

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.
Tang FL, Erion JR, Tian Y, Liu W, Yin DM, Ye J, Tang B, Mei L, Xiong WC
The Journal of neuroscience : the official journal of the Society for Neuroscience35(29)10613-28(2015 Jul)

The novel helicase helG (DHX30) is expressed during gastrulation in mice and has a structure similar to a human DExH box helicase.
Zheng HJ, Tsukahara M, Liu E, Ye L, Xiong H, Noguchi S, Suzuki K, Ji ZS
Stem cells and development24(3)372-83(2015 Feb)

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Gallon M, Clairfeuille T, Steinberg F, Mas C, Ghai R, Sessions RB, Teasdale RD, Collins BM, Cullen PJ
Proceedings of the National Academy of Sciences of the United States of America111(35)E3604-13(2014 Sep)

Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis.
Liu W, Tang FL, Erion J, Xiao H, Ye J, Xiong WC
Molecular brain710(2014 Feb)

Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromer.
Helfer E, Harbour ME, Henriot V, Lakisic G, Sousa-Blin C, Volceanov L, Seaman MNJ, Gautreau A
Biology of the cell105(5)191-207(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Vps26a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vps26a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04994	NM_001113355.1 Latest version!	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu44550	NM_001358543.1 Latest version!	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu44550	XM_006513734.3 Latest version!	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu10060	NM_133672.3 Latest version!	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vps26a ( NM_001113355.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001106826.1 Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu04994
Clone ID Related Accession (Same CDS sequence)	NM_001113355.1
Accession Version	NM_001113355.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576425600000
Organism	Mus musculus(house mouse)
Product	vacuolar protein sorting-associated protein 26A isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK028096.1, AK167592.1, AK147989.1 and CO801094.2. Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. These differences cause translation initiation at a downstream ATG and an isoform (b) with a longer, distinct N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK028096.1, SRR1660813.99455.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGAGC CTCTGCCCGC CTTCCTCGAC CGGCTGTGGG GACCCTGGCT GGGCACCCGC 
AGCCCGCCCA GCCGGAGCTC GGCAGCCTCG CCTTCCAAGA GTTTTCTTGG AGGCTTTTTT 
GGTCCCATTT GTGAGATTGA TGTTGCCCTT AATGATGGGG AAACCAGGAA AATGGCAGAA 
ATGAAAACTG AGGATGGCAA AGTAGAAAAA CACTATCTCT TCTATGATGG CGAGTCTGTC 
TCAGGAAAGG TAAACCTAGC CTTTAAGCAG CCTGGAAAGA GGCTAGAGCA TCAAGGAATT 
AGAATTGAAT TTGTAGGTCA AATTGAGCTT TTCAATGACA AGAGTAATAC TCATGAATTT 
GTAAACCTAG TGAAGGAACT AGCCTTGCCT GGAGAACTGA CTCAGAGCAG AAGCTATGAC 
TTTGAATTTA TGCAAGTTGA AAAGCCATAT GAGTCATACA TCGGTGCCAA TGTCCGCCTG 
AGGTATTTTC TTAAGGTGAC AATTGTGAGA AGATTGACAG ACTTAGTGAA AGAGTACGAT 
CTTATTGTTC ATCAGCTAGC CACCTATCCT GATGTCAACA ACTCTATTAA AATGGAAGTG 
GGCATTGAAG ACTGTCTGCA CATAGAGTTT GAATATAATA AGTCCAAGTA TCATTTAAAG 
GATGTAATTG TTGGAAAAAT TTACTTCTTA TTAGTAAGAA TAAAAATACA ACACATGGAA 
TTACAGCTGA TCAAGAAAGA GATCACAGGA ATTGGACCCA GCACCACAAC AGAGACAGAA 
ACAATCGCTA AGTATGAAAT AATGGATGGG GCGCCAGTAA AAGGAGAATC TATTCCGATA 
AGATTGTTCT TAGCAGGGTA TGACCCAACC CCCACGATGA GAGATGTGAA CAAGAAGTTT 
TCAGTAAGGT ACTTTCTAAA CCTCGTGCTT GTTGATGAGG AGGACCGAAG GTACTTCAAG 
CAGCAGGAGA TCATCCTGTG GAGAAAAGCA CCCGAGAAAC TGAGAAAACA GAGGACGAAC 
TTTCACCAGC GGTTTGAATC TCCAGACTCG CAGGCCTCTG CGGAGCAGCC TGAGATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106826.1
CDS	123..1202
Translation	MSEPLPAFLDRLWGPWLGTRSPPSRSSAASPSKSFLGGFFGPICEIDVALNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPDSQASAEQPEM

Target ORF information:

RefSeq Version	NM_001113355.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001113355.1

ORF Insert Sequence:

ATGTCGGAGC CTCTGCCCGC CTTCCTCGAC CGGCTGTGGG GACCCTGGCT GGGCACCCGC 
AGCCCGCCCA GCCGGAGCTC GGCAGCCTCG CCTTCCAAGA GTTTTCTTGG AGGCTTTTTT 
GGTCCCATTT GTGAGATTGA TGTTGCCCTT AATGATGGGG AAACCAGGAA AATGGCAGAA 
ATGAAAACTG AGGATGGCAA AGTAGAAAAA CACTATCTCT TCTATGATGG CGAGTCTGTC 
TCAGGAAAGG TAAACCTAGC CTTTAAGCAG CCTGGAAAGA GGCTAGAGCA TCAAGGAATT 
AGAATTGAAT TTGTAGGTCA AATTGAGCTT TTCAATGACA AGAGTAATAC TCATGAATTT 
GTAAACCTAG TGAAGGAACT AGCCTTGCCT GGAGAACTGA CTCAGAGCAG AAGCTATGAC 
TTTGAATTTA TGCAAGTTGA AAAGCCATAT GAGTCATACA TCGGTGCCAA TGTCCGCCTG 
AGGTATTTTC TTAAGGTGAC AATTGTGAGA AGATTGACAG ACTTAGTGAA AGAGTACGAT 
CTTATTGTTC ATCAGCTAGC CACCTATCCT GATGTCAACA ACTCTATTAA AATGGAAGTG 
GGCATTGAAG ACTGTCTGCA CATAGAGTTT GAATATAATA AGTCCAAGTA TCATTTAAAG 
GATGTAATTG TTGGAAAAAT TTACTTCTTA TTAGTAAGAA TAAAAATACA ACACATGGAA 
TTACAGCTGA TCAAGAAAGA GATCACAGGA ATTGGACCCA GCACCACAAC AGAGACAGAA 
ACAATCGCTA AGTATGAAAT AATGGATGGG GCGCCAGTAA AAGGAGAATC TATTCCGATA 
AGATTGTTCT TAGCAGGGTA TGACCCAACC CCCACGATGA GAGATGTGAA CAAGAAGTTT 
TCAGTAAGGT ACTTTCTAAA CCTCGTGCTT GTTGATGAGG AGGACCGAAG GTACTTCAAG 
CAGCAGGAGA TCATCCTGTG GAGAAAAGCA CCCGAGAAAC TGAGAAAACA GAGGACGAAC 
TTTCACCAGC GGTTTGAATC TCCAGACTCG CAGGCCTCTG CGGAGCAGCC TGAGATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vps26a ( NM_001358543.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001345472.1 Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu44550
Clone ID Related Accession (Same CDS sequence)	XM_006513734.3 , NM_001358543.1
Accession Version	NM_001358543.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576425600000
Organism	Mus musculus(house mouse)
Product	vacuolar protein sorting-associated protein 26A isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB857335.1, AK167592.1, CJ151367.1, AK147989.1 and CO801094.2. On Dec 1, 2017 this sequence version replaced XM_006513734.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660821.5495.1, SRR1660815.11799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAGTTG AAAAGCCATA TGAGTCATAC ATCGGTGCCA ATGTCCGCCT GAGGTATTTT 
CTTAAGGTGA CAATTGTGAG AAGATTGACA GACTTAGTGA AAGAGTACGA TCTTATTGTT 
CATCAGCTAG CCACCTATCC TGATGTCAAC AACTCTATTA AAATGGAAGT GGGCATTGAA 
GACTGTCTGC ACATAGAGTT TGAATATAAT AAGTCCAAGT ATCATTTAAA GGATGTAATT 
GTTGGAAAAA TTTACTTCTT ATTAGTAAGA ATAAAAATAC AACACATGGA ATTACAGCTG 
ATCAAGAAAG AGATCACAGG AATTGGACCC AGCACCACAA CAGAGACAGA AACAATCGCT 
AAGTATGAAA TAATGGATGG GGCGCCAGTA AAAGGAGAAT CTATTCCGAT AAGATTGTTC 
TTAGCAGGGT ATGACCCAAC CCCCACGATG AGAGATGTGA ACAAGAAGTT TTCAGTAAGG 
TACTTTCTAA ACCTCGTGCT TGTTGATGAG GAGGACCGAA GGTACTTCAA GCAGCAGGAG 
ATCATCCTGT GGAGAAAAGC ACCCGAGAAA CTGAGAAAAC AGAGGACGAA CTTTCACCAG 
CGGTTTGAAT CTCCAGACTC GCAGGCCTCT GCGGAGCAGC CTGAGATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001345472.1
CDS	403..1053
Translation	MQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPDSQASAEQPEM

Target ORF information:

RefSeq Version	NM_001358543.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001358543.1

ORF Insert Sequence:

ATGCAAGTTG AAAAGCCATA TGAGTCATAC ATCGGTGCCA ATGTCCGCCT GAGGTATTTT 
CTTAAGGTGA CAATTGTGAG AAGATTGACA GACTTAGTGA AAGAGTACGA TCTTATTGTT 
CATCAGCTAG CCACCTATCC TGATGTCAAC AACTCTATTA AAATGGAAGT GGGCATTGAA 
GACTGTCTGC ACATAGAGTT TGAATATAAT AAGTCCAAGT ATCATTTAAA GGATGTAATT 
GTTGGAAAAA TTTACTTCTT ATTAGTAAGA ATAAAAATAC AACACATGGA ATTACAGCTG 
ATCAAGAAAG AGATCACAGG AATTGGACCC AGCACCACAA CAGAGACAGA AACAATCGCT 
AAGTATGAAA TAATGGATGG GGCGCCAGTA AAAGGAGAAT CTATTCCGAT AAGATTGTTC 
TTAGCAGGGT ATGACCCAAC CCCCACGATG AGAGATGTGA ACAAGAAGTT TTCAGTAAGG 
TACTTTCTAA ACCTCGTGCT TGTTGATGAG GAGGACCGAA GGTACTTCAA GCAGCAGGAG 
ATCATCCTGT GGAGAAAAGC ACCCGAGAAA CTGAGAAAAC AGAGGACGAA CTTTCACCAG 
CGGTTTGAAT CTCCAGACTC GCAGGCCTCT GCGGAGCAGC CTGAGATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vps26a ( XM_006513734.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513797.1 Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44550
Clone ID Related Accession (Same CDS sequence)	XM_006513734.3 , NM_001358543.1
Accession Version	XM_006513734.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(House mouse)
Product	vacuolar protein sorting-associated protein 26A isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006513734.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAGTTG AAAAGCCATA TGAGTCATAC ATCGGTGCCA ATGTCCGCCT GAGGTATTTT 
CTTAAGGTGA CAATTGTGAG AAGATTGACA GACTTAGTGA AAGAGTACGA TCTTATTGTT 
CATCAGCTAG CCACCTATCC TGATGTCAAC AACTCTATTA AAATGGAAGT GGGCATTGAA 
GACTGTCTGC ACATAGAGTT TGAATATAAT AAGTCCAAGT ATCATTTAAA GGATGTAATT 
GTTGGAAAAA TTTACTTCTT ATTAGTAAGA ATAAAAATAC AACACATGGA ATTACAGCTG 
ATCAAGAAAG AGATCACAGG AATTGGACCC AGCACCACAA CAGAGACAGA AACAATCGCT 
AAGTATGAAA TAATGGATGG GGCGCCAGTA AAAGGAGAAT CTATTCCGAT AAGATTGTTC 
TTAGCAGGGT ATGACCCAAC CCCCACGATG AGAGATGTGA ACAAGAAGTT TTCAGTAAGG 
TACTTTCTAA ACCTCGTGCT TGTTGATGAG GAGGACCGAA GGTACTTCAA GCAGCAGGAG 
ATCATCCTGT GGAGAAAAGC ACCCGAGAAA CTGAGAAAAC AGAGGACGAA CTTTCACCAG 
CGGTTTGAAT CTCCAGACTC GCAGGCCTCT GCGGAGCAGC CTGAGATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513797.1
CDS	393..1043
Translation	MQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPDSQASAEQPEM

Target ORF information:

RefSeq Version	XM_006513734.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513734.3

ORF Insert Sequence:

ATGCAAGTTG AAAAGCCATA TGAGTCATAC ATCGGTGCCA ATGTCCGCCT GAGGTATTTT 
CTTAAGGTGA CAATTGTGAG AAGATTGACA GACTTAGTGA AAGAGTACGA TCTTATTGTT 
CATCAGCTAG CCACCTATCC TGATGTCAAC AACTCTATTA AAATGGAAGT GGGCATTGAA 
GACTGTCTGC ACATAGAGTT TGAATATAAT AAGTCCAAGT ATCATTTAAA GGATGTAATT 
GTTGGAAAAA TTTACTTCTT ATTAGTAAGA ATAAAAATAC AACACATGGA ATTACAGCTG 
ATCAAGAAAG AGATCACAGG AATTGGACCC AGCACCACAA CAGAGACAGA AACAATCGCT 
AAGTATGAAA TAATGGATGG GGCGCCAGTA AAAGGAGAAT CTATTCCGAT AAGATTGTTC 
TTAGCAGGGT ATGACCCAAC CCCCACGATG AGAGATGTGA ACAAGAAGTT TTCAGTAAGG 
TACTTTCTAA ACCTCGTGCT TGTTGATGAG GAGGACCGAA GGTACTTCAA GCAGCAGGAG 
ATCATCCTGT GGAGAAAAGC ACCCGAGAAA CTGAGAAAAC AGAGGACGAA CTTTCACCAG 
CGGTTTGAAT CTCCAGACTC GCAGGCCTCT GCGGAGCAGC CTGAGATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vps26a ( NM_133672.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598433.1 Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10060
Clone ID Related Accession (Same CDS sequence)	NM_133672.3
Accession Version	NM_133672.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576425600000
Organism	Mus musculus(house mouse)
Product	vacuolar protein sorting-associated protein 26A isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB857335.1, AK167592.1, AK147989.1 and CO801094.2. On Jan 9, 2008 this sequence version replaced NM_133672.2. Transcript Variant: This variant (1) encodes isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK168213.1, AK147989.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTTTTC TTGGAGGCTT TTTTGGTCCC ATTTGTGAGA TTGATGTTGC CCTTAATGAT 
GGGGAAACCA GGAAAATGGC AGAAATGAAA ACTGAGGATG GCAAAGTAGA AAAACACTAT 
CTCTTCTATG ATGGCGAGTC TGTCTCAGGA AAGGTAAACC TAGCCTTTAA GCAGCCTGGA 
AAGAGGCTAG AGCATCAAGG AATTAGAATT GAATTTGTAG GTCAAATTGA GCTTTTCAAT 
GACAAGAGTA ATACTCATGA ATTTGTAAAC CTAGTGAAGG AACTAGCCTT GCCTGGAGAA 
CTGACTCAGA GCAGAAGCTA TGACTTTGAA TTTATGCAAG TTGAAAAGCC ATATGAGTCA 
TACATCGGTG CCAATGTCCG CCTGAGGTAT TTTCTTAAGG TGACAATTGT GAGAAGATTG 
ACAGACTTAG TGAAAGAGTA CGATCTTATT GTTCATCAGC TAGCCACCTA TCCTGATGTC 
AACAACTCTA TTAAAATGGA AGTGGGCATT GAAGACTGTC TGCACATAGA GTTTGAATAT 
AATAAGTCCA AGTATCATTT AAAGGATGTA ATTGTTGGAA AAATTTACTT CTTATTAGTA 
AGAATAAAAA TACAACACAT GGAATTACAG CTGATCAAGA AAGAGATCAC AGGAATTGGA 
CCCAGCACCA CAACAGAGAC AGAAACAATC GCTAAGTATG AAATAATGGA TGGGGCGCCA 
GTAAAAGGAG AATCTATTCC GATAAGATTG TTCTTAGCAG GGTATGACCC AACCCCCACG 
ATGAGAGATG TGAACAAGAA GTTTTCAGTA AGGTACTTTC TAAACCTCGT GCTTGTTGAT 
GAGGAGGACC GAAGGTACTT CAAGCAGCAG GAGATCATCC TGTGGAGAAA AGCACCCGAG 
AAACTGAGAA AACAGAGGAC GAACTTTCAC CAGCGGTTTG AATCTCCAGA CTCGCAGGCC 
TCTGCGGAGC AGCCTGAGAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598433.1
CDS	146..1129
Translation	MSFLGGFFGPICEIDVALNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPDSQASAEQPEM

Target ORF information:

RefSeq Version	NM_133672.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus VPS26 retromer complex component A (Vps26a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133672.3

ORF Insert Sequence:

ATGAGTTTTC TTGGAGGCTT TTTTGGTCCC ATTTGTGAGA TTGATGTTGC CCTTAATGAT 
GGGGAAACCA GGAAAATGGC AGAAATGAAA ACTGAGGATG GCAAAGTAGA AAAACACTAT 
CTCTTCTATG ATGGCGAGTC TGTCTCAGGA AAGGTAAACC TAGCCTTTAA GCAGCCTGGA 
AAGAGGCTAG AGCATCAAGG AATTAGAATT GAATTTGTAG GTCAAATTGA GCTTTTCAAT 
GACAAGAGTA ATACTCATGA ATTTGTAAAC CTAGTGAAGG AACTAGCCTT GCCTGGAGAA 
CTGACTCAGA GCAGAAGCTA TGACTTTGAA TTTATGCAAG TTGAAAAGCC ATATGAGTCA 
TACATCGGTG CCAATGTCCG CCTGAGGTAT TTTCTTAAGG TGACAATTGT GAGAAGATTG 
ACAGACTTAG TGAAAGAGTA CGATCTTATT GTTCATCAGC TAGCCACCTA TCCTGATGTC 
AACAACTCTA TTAAAATGGA AGTGGGCATT GAAGACTGTC TGCACATAGA GTTTGAATAT 
AATAAGTCCA AGTATCATTT AAAGGATGTA ATTGTTGGAA AAATTTACTT CTTATTAGTA 
AGAATAAAAA TACAACACAT GGAATTACAG CTGATCAAGA AAGAGATCAC AGGAATTGGA 
CCCAGCACCA CAACAGAGAC AGAAACAATC GCTAAGTATG AAATAATGGA TGGGGCGCCA 
GTAAAAGGAG AATCTATTCC GATAAGATTG TTCTTAGCAG GGTATGACCC AACCCCCACG 
ATGAGAGATG TGAACAAGAA GTTTTCAGTA AGGTACTTTC TAAACCTCGT GCTTGTTGAT 
GAGGAGGACC GAAGGTACTT CAAGCAGCAG GAGATCATCC TGTGGAGAAA AGCACCCGAG 
AAACTGAGAA AACAGAGGAC GAACTTTCAC CAGCGGTTTG AATCTCCAGA CTCGCAGGCC 
TCTGCGGAGC AGCCTGAGAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(29)10613-28(2015 Jul)
Tang FL,Erion JR,Tian Y,Liu W,Yin DM,Ye J,Tang B,Mei L,Xiong WC

The novel helicase helG (DHX30) is expressed during gastrulation in mice and has a structure similar to a human DExH box helicase.
Stem cells and development24(3)372-83(2015 Feb)
Zheng HJ,Tsukahara M,Liu E,Ye L,Xiong H,Noguchi S,Suzuki K,Ji ZS

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Proceedings of the National Academy of Sciences of the United States of America111(35)E3604-13(2014 Sep)
Gallon M,Clairfeuille T,Steinberg F,Mas C,Ghai R,Sessions RB,Teasdale RD,Collins BM,Cullen PJ

Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis.
Molecular brain710(2014 Feb)
Liu W,Tang FL,Erion J,Xiao H,Ye J,Xiong WC

Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromer.
Biology of the cell105(5)191-207(2013 May)
Helfer E,Harbour ME,Henriot V,Lakisic G,Sousa-Blin C,Volceanov L,Seaman MNJ,Gautreau A

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Vps26a cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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