| Gene Symbol | Selenov |
| Entrez Gene ID | 280621 |
| Full Name | selenoprotein V |
| Synonyms | Selv |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome | |
| Summary | This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is specifically expressed in the testis. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. [provided by RefSeq, Apr 2017]. |
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Selenov cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Selenov gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Selenov cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu04806 Clone ID Related Accession (Same CDS sequence) NM_175033.4 Accession Version NM_175033.4 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1567958400000 Organism Mus musculus(house mouse) Product selenoprotein V Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK077113.2 and BC089491.1. On Apr 24, 2017 this sequence version replaced NM_175033.3. ##Evidence-Data-START## Transcript exon combination :: BC089491.1, AK077113.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred from conservation protein contains selenocysteine :: PMID: 12775843 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961ATGAATAACA AGGCGCGGGT CCCCGCTCCC TCCTCAGTCC GGGCAAACAC CCCGGCCCGG
ACACCCGCTC CCATCCGAAC CGCGACCCCA GTCAGGGCCC CGAACCCAGC GCACAACTCG
ACTCCAGTCC GAACTTCCAT CCGGGTCCGG GCTCCTGCCC AAGTCCCTAA CCCTGTTCCA
ATCCGGTTCC CAACTCCAGC CCCAGTCCCT GCCCCAACCC TAACCCCAGC CCCAACTCCA
GCTCCAGTCC GGCATGCAGC ACCGGTGCGG ACTCCAGCAC CAGTCCGGGC CCCGAATCTA
GGTCGGGTCT TTCCTAAGAT CTCTCCAGGC AGGTTCTTCC CGAGCTTGGC CTCGCCCACG
GCACAGCCCC TTTCTTCCAG GGCTGCTAGC GCTCTCTTGA AGGATCCCAC ACTCGCTCAA
AATCAGAAAC CCTCGATCCA CAGCCTAGCG GAGGCCATCC AGGGGCCCCT TCCAGTGCTC
ACTCCCTCGT CCTCCAAGAC ACAAGGCTCC ATACCGGACA CCGCCTCTCC CATAGACTCC
TTGGCTTCTA CTGCCATGGC CTCCAGTACA TTGGGCCCCA TTCCGGGCCC CAACCCTACA
CTAGAGTTCT TGGCCTCCCC GCTGAAGGAA ACCCCTGGTC TGGGTAAGCT CTCCACGATT
TCCCCAGCAC CCAGCTTCGG TTCCACTAAG GAGATCCCAT CCACCAGCGA GGACGTCCCA
ACGCCCAACA GAATCTTGAT CCGTGTGATG TACTGTGGCC TCTGAAGCTA TGGCCTTCGG
TACATTATAC TGAAAAGGAC CCTGGAGCAT CAATTCCCAA ACCTTCTGGA GTTTGAGGAG
GAAAGAGCTA CCCAGGTTAC AGGGGAGTTT GAAGTGTTTG TGGATGGGAA GCTGATCCAT
TCCAAGAAGA AAGGTGATGG CTTTGTGGAT GAGTCCGGTC TGAAGAAACT TGTGGGTGCT
ATTGACGAAG AGATCAAGAA GAGGTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_778198.2 CDS 110..1096 Translation 
Target ORF information:
RefSeq Version NM_175033.4 Organism Mus musculus(house mouse) Definition Mus musculus selenoprotein V (Selenov), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_175033.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961ATGAATAACA AGGCGCGGGT CCCCGCTCCC TCCTCAGTCC GGGCAAACAC CCCGGCCCGG
ACACCCGCTC CCATCCGAAC CGCGACCCCA GTCAGGGCCC CGAACCCAGC GCACAACTCG
ACTCCAGTCC GAACTTCCAT CCGGGTCCGG GCTCCTGCCC AAGTCCCTAA CCCTGTTCCA
ATCCGGTTCC CAACTCCAGC CCCAGTCCCT GCCCCAACCC TAACCCCAGC CCCAACTCCA
GCTCCAGTCC GGCATGCAGC ACCGGTGCGG ACTCCAGCAC CAGTCCGGGC CCCGAATCTA
GGTCGGGTCT TTCCTAAGAT CTCTCCAGGC AGGTTCTTCC CGAGCTTGGC CTCGCCCACG
GCACAGCCCC TTTCTTCCAG GGCTGCTAGC GCTCTCTTGA AGGATCCCAC ACTCGCTCAA
AATCAGAAAC CCTCGATCCA CAGCCTAGCG GAGGCCATCC AGGGGCCCCT TCCAGTGCTC
ACTCCCTCGT CCTCCAAGAC ACAAGGCTCC ATACCGGACA CCGCCTCTCC CATAGACTCC
TTGGCTTCTA CTGCCATGGC CTCCAGTACA TTGGGCCCCA TTCCGGGCCC CAACCCTACA
CTAGAGTTCT TGGCCTCCCC GCTGAAGGAA ACCCCTGGTC TGGGTAAGCT CTCCACGATT
TCCCCAGCAC CCAGCTTCGG TTCCACTAAG GAGATCCCAT CCACCAGCGA GGACGTCCCA
ACGCCCAACA GAATCTTGAT CCGTGTGATG TACTGTGGCC TCTGAAGCTA TGGCCTTCGG
TACATTATAC TGAAAAGGAC CCTGGAGCAT CAATTCCCAA ACCTTCTGGA GTTTGAGGAG
GAAAGAGCTA CCCAGGTTAC AGGGGAGTTT GAAGTGTTTG TGGATGGGAA GCTGATCCAT
TCCAAGAAGA AAGGTGATGG CTTTGTGGAT GAGTCCGGTC TGAAGAAACT TGTGGGTGCT
ATTGACGAAG AGATCAAGAA GAGGTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arnér ES,Berry MJ,Brigelius-Flohé R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Flohé L,Green FR,Guigó R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,Köhrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonović M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y
Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.
Proceedings of the National Academy of Sciences of the United States of America113(28)7704-10(2016 07)
Miyata H,Castaneda JM,Fujihara Y,Yu Z,Archambeault DR,Isotani A,Kiyozumi D,Kriseman ML,Mashiko D,Matsumura T,Matzuk RM,Mori M,Noda T,Oji A,Okabe M,Prunskaite-Hyyrylainen R,Ramirez-Solis R,Satouh Y,Zhang Q,Ikawa M,Matzuk MM
[cDNA cloning, expression and determination of substrate specificity of mice selenocysteine-containing protein SelV (Selenoprotein V)].
Molekuliarnaia biologiia49(5)785-9(2015 Sep-Oct)
Varlamova EG,Novoselov SV,Novoselov VI
Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN
Characterization of mammalian selenoproteomes.
Science (New York, N.Y.)300(5624)1439-43(2003 May)
Kryukov GV,Castellano S,Novoselov SV,Lobanov AV,Zehtab O,Guigó R,Gladyshev VN
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