| Gene Symbol | Ing4 |
| Entrez Gene ID | 28019 |
| Full Name | inhibitor of growth family, member 4 |
| Synonyms | D6Wsu147e,D6Xrf92,p29ING4 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Ing4 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Ing4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ing4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu84531 Clone ID Related Accession (Same CDS sequence) NM_001368695.1 Accession Version NM_001368695.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 750bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577808000000 Organism Mus musculus(house mouse) Product inhibitor of growth protein 4 isoform 2 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC134529.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.2522546.1, SRR5189676.67640.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721ATGGCTGCTG GGATGTATTT GGAACATTAT CTGGACAGTA TTGAAAACCT CCCGTTTGAA
TTACAGAGAA ACTTTCAGCT CATGAGGGAC CTAGACCAAA GGACAGAGGA CCTGAAGGCT
GAAATTGACA AGTTGGCCAC TGAATATATG AGTAGCGCCC GCAGCCTGAG CTCCGAGGAG
AAGCTGGCCC TTCTCAGACA GATCCAGGAG GCCTATGGCA AGTGCAAGGA ATTTGGTGAC
GACAAGGTGC AGCTGGCCAT GCAGACCTAT GAGATGGTAG ACAAACACAT TCGGCGGCTG
GACACAGACC TGGCCCGTTT TGAGGCTGAT CTGAAGGAGA AACAGATCGA GTCCAGTGAC
TATGACAGCT CTTCTAGCAA AGGCAAAAAG AAAGGCCGGA CCCAAAAGGA GAAAAAAGCT
GCCAGAGCCC GTTCCAAAGG GAAAAACTCA GATGAAGAAG CCCCCAAGGC TGCCCAGAAG
AAGTTAAAAC TTGTGCGCAC AAGTCCTGAG TATGGGATGC CCTCAGTGAC CTTTGGCAGT
GTCCACCCCT CTGATGTGTT GGATATGCCT GTGGATCCCA ACGAACCCAC ATATTGCCTT
TGTCACCAGG TCTCCTATGG AGAGATGATT GGCTGTGACA ACCCGGATTG TTCCATCGAG
TGGTTCCACT TCGCCTGTGT GGGGCTGACA ACCAAACCTC GAGGGAAATG GTTTTGCCCA
CGCTGCTCCC AAGAACGGAA GAAGAAATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001355624.1 CDS 14..763 Translation 
Target ORF information:
RefSeq Version NM_001368695.1 Organism Mus musculus(house mouse) Definition Mus musculus inhibitor of growth family, member 4 (Ing4), transcript variant 2, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001368695.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGGCTGCTG GGATGTATTT GGAACATTAT CTGGACAGTA TTGAAAACCT CCCGTTTGAA
TTACAGAGAA ACTTTCAGCT CATGAGGGAC CTAGACCAAA GGACAGAGGA CCTGAAGGCT
GAAATTGACA AGTTGGCCAC TGAATATATG AGTAGCGCCC GCAGCCTGAG CTCCGAGGAG
AAGCTGGCCC TTCTCAGACA GATCCAGGAG GCCTATGGCA AGTGCAAGGA ATTTGGTGAC
GACAAGGTGC AGCTGGCCAT GCAGACCTAT GAGATGGTAG ACAAACACAT TCGGCGGCTG
GACACAGACC TGGCCCGTTT TGAGGCTGAT CTGAAGGAGA AACAGATCGA GTCCAGTGAC
TATGACAGCT CTTCTAGCAA AGGCAAAAAG AAAGGCCGGA CCCAAAAGGA GAAAAAAGCT
GCCAGAGCCC GTTCCAAAGG GAAAAACTCA GATGAAGAAG CCCCCAAGGC TGCCCAGAAG
AAGTTAAAAC TTGTGCGCAC AAGTCCTGAG TATGGGATGC CCTCAGTGAC CTTTGGCAGT
GTCCACCCCT CTGATGTGTT GGATATGCCT GTGGATCCCA ACGAACCCAC ATATTGCCTT
TGTCACCAGG TCTCCTATGG AGAGATGATT GGCTGTGACA ACCCGGATTG TTCCATCGAG
TGGTTCCACT TCGCCTGTGT GGGGCTGACA ACCAAACCTC GAGGGAAATG GTTTTGCCCA
CGCTGCTCCC AAGAACGGAA GAAGAAATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OMu15065 Clone ID Related Accession (Same CDS sequence) NM_133345.2 Accession Version NM_133345.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 747bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577203200000 Organism Mus musculus(house mouse) Product inhibitor of growth protein 4 isoform 1 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK009267.1. On Apr 6, 2007 this sequence version replaced NM_133345.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK009267.1, AK050522.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721ATGGCTGCTG GGATGTATTT GGAACATTAT CTGGACAGTA TTGAAAACCT CCCGTTTGAA
TTACAGAGAA ACTTTCAGCT CATGAGGGAC CTAGACCAAA GGACAGAGGA CCTGAAGGCT
GAAATTGACA AGTTGGCCAC TGAATATATG AGTAGCGCCC GCAGCCTGAG CTCCGAGGAG
AAGCTGGCCC TTCTCAGACA GATCCAGGAG GCCTATGGCA AGTGCAAGGA ATTTGGTGAC
GACAAGGTGC AGCTGGCCAT GCAGACCTAT GAGATGGTAG ACAAACACAT TCGGCGGCTG
GACACAGACC TGGCCCGTTT TGAGGCTGAT CTGAAGGAGA AACAGATCGA GTCCAGTGAC
TATGACAGCT CTTCTAGCAA AGGCAAAAAG AGCCGGACCC AAAAGGAGAA AAAAGCTGCC
AGAGCCCGTT CCAAAGGGAA AAACTCAGAT GAAGAAGCCC CCAAGGCTGC CCAGAAGAAG
TTAAAACTTG TGCGCACAAG TCCTGAGTAT GGGATGCCCT CAGTGACCTT TGGCAGTGTC
CACCCCTCTG ATGTGTTGGA TATGCCTGTG GATCCCAACG AACCCACATA TTGCCTTTGT
CACCAGGTCT CCTATGGAGA GATGATTGGC TGTGACAACC CGGATTGTTC CATCGAGTGG
TTCCACTTCG CCTGTGTGGG GCTGACAACC AAACCTCGAG GGAAATGGTT TTGCCCACGC
TGCTCCCAAG AACGGAAGAA GAAATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_579923.1 CDS 14..760 Translation
Target ORF information:
RefSeq Version NM_133345.2 Organism Mus musculus(house mouse) Definition Mus musculus inhibitor of growth family, member 4 (Ing4), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_133345.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGGCTGCTG GGATGTATTT GGAACATTAT CTGGACAGTA TTGAAAACCT CCCGTTTGAA
TTACAGAGAA ACTTTCAGCT CATGAGGGAC CTAGACCAAA GGACAGAGGA CCTGAAGGCT
GAAATTGACA AGTTGGCCAC TGAATATATG AGTAGCGCCC GCAGCCTGAG CTCCGAGGAG
AAGCTGGCCC TTCTCAGACA GATCCAGGAG GCCTATGGCA AGTGCAAGGA ATTTGGTGAC
GACAAGGTGC AGCTGGCCAT GCAGACCTAT GAGATGGTAG ACAAACACAT TCGGCGGCTG
GACACAGACC TGGCCCGTTT TGAGGCTGAT CTGAAGGAGA AACAGATCGA GTCCAGTGAC
TATGACAGCT CTTCTAGCAA AGGCAAAAAG AGCCGGACCC AAAAGGAGAA AAAAGCTGCC
AGAGCCCGTT CCAAAGGGAA AAACTCAGAT GAAGAAGCCC CCAAGGCTGC CCAGAAGAAG
TTAAAACTTG TGCGCACAAG TCCTGAGTAT GGGATGCCCT CAGTGACCTT TGGCAGTGTC
CACCCCTCTG ATGTGTTGGA TATGCCTGTG GATCCCAACG AACCCACATA TTGCCTTTGT
CACCAGGTCT CCTATGGAGA GATGATTGGC TGTGACAACC CGGATTGTTC CATCGAGTGG
TTCCACTTCG CCTGTGTGGG GCTGACAACC AAACCTCGAG GGAAATGGTT TTGCCCACGC
TGCTCCCAAG AACGGAAGAA GAAATAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma.
Molecular therapy : the journal of the American Society of Gene Therapy25(7)1556-1566(2017 07)
Wang S,Reinhard S,Li C,Qian M,Jiang H,Du Y,Lächelt U,Lu W,Wagner E,Huang R
ING4 Inhibits Proliferation and Induces Apoptosis in Human Melanoma A375 Cells via the Fas/Caspase-8 Apoptosis Pathway.
Dermatology (Basel, Switzerland)232(3)265-72(2016)
Ma Y,Cheng X,Wang F,Pan J,Liu J,Chen H,Wang Y,Cai L
Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity.
Proceedings of the National Academy of Sciences of the United States of America107(25)11423-8(2010 Jun)
Coles AH,Gannon H,Cerny A,Kurt-Jones E,Jones SN
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Developmental cell18(4)675-85(2010 Apr)
Guo G,Huss M,Tong GQ,Wang C,Li Sun L,Clarke ND,Robson P
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H
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