Mkln1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mkln1
Entrez Gene ID	27418
Full Name	muskelin 1, intracellular mediator containing kelch motifs
Synonyms	A130067F06Rik,AU015903,BB154892
General protein information	Preferred Names muskelin 1, intracellular mediator containing kelch motifs Names muskelin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_017321605.2	XP_017177094.1	muskelin isoform X2
XM_017321606.1	XP_017177095.1	muskelin isoform X2
XM_030255437.1	XP_030111297.1	muskelin isoform X3
NM_013791.2	NP_038819.1	muskelin
XM_030255436.1	XP_030111296.1	muskelin isoform X1
XM_017321605.1	XP_017177094.1	muskelin isoform X1

Pathways from BioSystems

Homologies

Schizosaccharomyces pombe (fission yeast)	mde6	NP_594297.2
Homo sapiens (human)	MKLN1	NP_037387.2
Canis lupus familiaris (dog)	MKLN1	XP_005628424.1
Macaca mulatta (Rhesus monkey)	MKLN1	XP_001098817.1
Bos taurus (cattle)	MKLN1	NP_001091468.1
Gallus gallus (chicken)	MKLN1	NP_001025944.1
Danio rerio (zebrafish)	mkln1	NP_997859.1
Drosophila melanogaster (fruit fly)	muskelin	NP_610801.1
Rattus norvegicus (Norway rat)	Mkln1	NP_112649.1
Mus musculus (house mouse)	Mkln1	NP_038819.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004884	XP_314298.3
Pan troglodytes (chimpanzee)	MKLN1	XP_519385.2
Xenopus tropicalis (tropical clawed frog)	mkln1	XP_002931895.1

Gene Ontology
Bibliography

Related articles in PubMed

Muskelin Coordinates PrP
Heisler FF, Pechmann Y, Wieser I, Altmeppen HC, Veenendaal L, Muhia M, Schweizer M, Glatzel M, Krasemann S, Kneussel M
Neuron99(6)1155-1169.e9(2018 09)

The LisH motif of muskelin is crucial for oligomerization and governs intracellular localization.
Delto CF, Heisler FF, Kuper J, Sander B, Kneussel M, Schindelin H
Structure (London, England : 1993)23(2)364-73(2015 Feb)

Structure of mouse muskelin discoidin domain and biochemical characterization of its self-association.
Kim KH, Hong SK, Hwang KY, Kim EE
Acta crystallographica. Section D, Biological crystallography70(Pt 11)2863-74(2014 Nov)

Characterization of the novel interaction between muskelin and TBX20, a critical cardiogenic transcription factor.
Debenedittis P, Harmelink C, Chen Y, Wang Q, Jiao K
Biochemical and biophysical research communications409(2)338-43(2011 Jun)

Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.
Heisler FF, Loebrich S, Pechmann Y, Maier N, Zivkovic AR, Tokito M, Hausrat TJ, Schweizer M, Bähring R, Holzbaur EL, Schmitz D, Kneussel M
Neuron70(1)66-81(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mkln1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mkln1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu81741	XM_017321606.1 Latest version!	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu81741	XM_030255437.1 Latest version!	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu20775	NM_013791.2 Latest version!	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu69289	XM_017321605.2 Latest version!	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu89220	XM_030255436.1 Latest version!	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu69289	XM_017321605.1	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mkln1 ( XM_017321606.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017177095.1 Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu81741
Clone ID Related Accession (Same CDS sequence)	XM_017321606.1 , XM_030255437.1
Accession Version	XM_017321606.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	muskelin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCATTG ACATTCAGCG GAGACAAATC TACACATTGG GCCGTTACTT GGATTCCTCT 
GTGAGGAACA GCAAATCTCT GAAAAGTGAT TTCTACCGTT ACGACATTGA CACTAATACC 
TGGATGTTAC TAAGTGAAGA TACTGCTGCC GACGGTGGAC CAAAGTTGGT GTTTGATCAT 
CAGATGTGTA TGGACTCAGA AAAACATATG ATCTACACGT TTGGTGGCAG GATTTTGACG 
TGTAATGGCA GTGTAGATGA CAGCAGAGCC AGTGAGCCAC AATTCAGTGG GTTGTTTGCG 
TTCAACTGCC AGTGTCAAAC TTGGAAACTT CTTCGAGAGG ATTCCTGTAA TGCTGGCCCT 
GAGGACATCC AGTCTCGGAT TGGACACTGC ATGCTGTTCC ACTCAAAAAA CCGTTGCTTA 
TATGTGTTTG GTGGCCAGAG ATCCAAGACC TATTTGAATG ATTTCTTTAG TTATGATGTG 
GACTCAGATC ATGTAGACAT AATTTCAGAT GGCACCAAGA AAGACTCTGG AATGGTTCCA 
ATGACCGGAT TCACACAGAG AGCAACTATT GATCCAGAAC TGAATGAAAT ACATGTCTTA 
TCCGGACTTA GCAAAGACAA AGAAAAGAGG GAAGAGAATG TCAGAAATTC ATTCTGGATT 
TATGACATTG TGAGGAATAG CTGGTCTTGT GTCTATAAGA ATGATCAAGC TACAAAAGAT 
AATCTGAGTA AAAGTCTTCA GGAGGAAGAA CCATGTCCAA GGTTTGCCCA TCAACTCGTT 
TATGATGAAT TACACAAGGT TCATTATTTA TTTGGTGGAA ATCCAGGAAA ATCTTGCTCT 
CCAAAGATGA GACTAGATGA CTTCTGGTCA CTGAAGTTGT GTAGACCTTC AAAAGACTAC 
TTACTGAGGC ATTGCAAGTA CCTCATAAGA AAACACAGGT TTGAAGAAAA GGCCCAAATG 
GATCCCCTTA GTGCTCTGAA GTATTTACAA AATGATCTTT ATATAACTGT GGATCATTCG 
GACCCAGAAG AGACAAAAGA GTTTCAACTC CTAGCCTCAG CTCTGTTCAA ATCTGGCTCA 
GATTTCACAG CTCTAGGCTT TTCAGATGTG GATCATACCT ATGCTCAAAG AACTCAGCTC 
TTTGACACCT TAGTAAATTT CTTTCCTGAC AGCATGACTC CTCCTAAAGG CAACCTGGTA 
GACCTGATCA CACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017177095.1
CDS	530..1747
Translation	MCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL

Target ORF information:

RefSeq Version	XM_017321606.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017321606.1

ORF Insert Sequence:

ATGTGCATTG ACATTCAGCG GAGACAAATC TACACATTGG GCCGTTACTT GGATTCCTCT 
GTGAGGAACA GCAAATCTCT GAAAAGTGAT TTCTACCGTT ACGACATTGA CACTAATACC 
TGGATGTTAC TAAGTGAAGA TACTGCTGCC GACGGTGGAC CAAAGTTGGT GTTTGATCAT 
CAGATGTGTA TGGACTCAGA AAAACATATG ATCTACACGT TTGGTGGCAG GATTTTGACG 
TGTAATGGCA GTGTAGATGA CAGCAGAGCC AGTGAGCCAC AATTCAGTGG GTTGTTTGCG 
TTCAACTGCC AGTGTCAAAC TTGGAAACTT CTTCGAGAGG ATTCCTGTAA TGCTGGCCCT 
GAGGACATCC AGTCTCGGAT TGGACACTGC ATGCTGTTCC ACTCAAAAAA CCGTTGCTTA 
TATGTGTTTG GTGGCCAGAG ATCCAAGACC TATTTGAATG ATTTCTTTAG TTATGATGTG 
GACTCAGATC ATGTAGACAT AATTTCAGAT GGCACCAAGA AAGACTCTGG AATGGTTCCA 
ATGACCGGAT TCACACAGAG AGCAACTATT GATCCAGAAC TGAATGAAAT ACATGTCTTA 
TCCGGACTTA GCAAAGACAA AGAAAAGAGG GAAGAGAATG TCAGAAATTC ATTCTGGATT 
TATGACATTG TGAGGAATAG CTGGTCTTGT GTCTATAAGA ATGATCAAGC TACAAAAGAT 
AATCTGAGTA AAAGTCTTCA GGAGGAAGAA CCATGTCCAA GGTTTGCCCA TCAACTCGTT 
TATGATGAAT TACACAAGGT TCATTATTTA TTTGGTGGAA ATCCAGGAAA ATCTTGCTCT 
CCAAAGATGA GACTAGATGA CTTCTGGTCA CTGAAGTTGT GTAGACCTTC AAAAGACTAC 
TTACTGAGGC ATTGCAAGTA CCTCATAAGA AAACACAGGT TTGAAGAAAA GGCCCAAATG 
GATCCCCTTA GTGCTCTGAA GTATTTACAA AATGATCTTT ATATAACTGT GGATCATTCG 
GACCCAGAAG AGACAAAAGA GTTTCAACTC CTAGCCTCAG CTCTGTTCAA ATCTGGCTCA 
GATTTCACAG CTCTAGGCTT TTCAGATGTG GATCATACCT ATGCTCAAAG AACTCAGCTC 
TTTGACACCT TAGTAAATTT CTTTCCTGAC AGCATGACTC CTCCTAAAGG CAACCTGGTA 
GACCTGATCA CACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mkln1 ( XM_030255437.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030111297.1 Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu81741
Clone ID Related Accession (Same CDS sequence)	XM_017321606.1 , XM_030255437.1
Accession Version	XM_030255437.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	muskelin isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCATTG ACATTCAGCG GAGACAAATC TACACATTGG GCCGTTACTT GGATTCCTCT 
GTGAGGAACA GCAAATCTCT GAAAAGTGAT TTCTACCGTT ACGACATTGA CACTAATACC 
TGGATGTTAC TAAGTGAAGA TACTGCTGCC GACGGTGGAC CAAAGTTGGT GTTTGATCAT 
CAGATGTGTA TGGACTCAGA AAAACATATG ATCTACACGT TTGGTGGCAG GATTTTGACG 
TGTAATGGCA GTGTAGATGA CAGCAGAGCC AGTGAGCCAC AATTCAGTGG GTTGTTTGCG 
TTCAACTGCC AGTGTCAAAC TTGGAAACTT CTTCGAGAGG ATTCCTGTAA TGCTGGCCCT 
GAGGACATCC AGTCTCGGAT TGGACACTGC ATGCTGTTCC ACTCAAAAAA CCGTTGCTTA 
TATGTGTTTG GTGGCCAGAG ATCCAAGACC TATTTGAATG ATTTCTTTAG TTATGATGTG 
GACTCAGATC ATGTAGACAT AATTTCAGAT GGCACCAAGA AAGACTCTGG AATGGTTCCA 
ATGACCGGAT TCACACAGAG AGCAACTATT GATCCAGAAC TGAATGAAAT ACATGTCTTA 
TCCGGACTTA GCAAAGACAA AGAAAAGAGG GAAGAGAATG TCAGAAATTC ATTCTGGATT 
TATGACATTG TGAGGAATAG CTGGTCTTGT GTCTATAAGA ATGATCAAGC TACAAAAGAT 
AATCTGAGTA AAAGTCTTCA GGAGGAAGAA CCATGTCCAA GGTTTGCCCA TCAACTCGTT 
TATGATGAAT TACACAAGGT TCATTATTTA TTTGGTGGAA ATCCAGGAAA ATCTTGCTCT 
CCAAAGATGA GACTAGATGA CTTCTGGTCA CTGAAGTTGT GTAGACCTTC AAAAGACTAC 
TTACTGAGGC ATTGCAAGTA CCTCATAAGA AAACACAGGT TTGAAGAAAA GGCCCAAATG 
GATCCCCTTA GTGCTCTGAA GTATTTACAA AATGATCTTT ATATAACTGT GGATCATTCG 
GACCCAGAAG AGACAAAAGA GTTTCAACTC CTAGCCTCAG CTCTGTTCAA ATCTGGCTCA 
GATTTCACAG CTCTAGGCTT TTCAGATGTG GATCATACCT ATGCTCAAAG AACTCAGCTC 
TTTGACACCT TAGTAAATTT CTTTCCTGAC AGCATGACTC CTCCTAAAGG CAACCTGGTA 
GACCTGATCA CACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030111297.1
CDS	887..2104
Translation	MCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL

Target ORF information:

RefSeq Version	XM_030255437.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030255437.1

ORF Insert Sequence:

ATGTGCATTG ACATTCAGCG GAGACAAATC TACACATTGG GCCGTTACTT GGATTCCTCT 
GTGAGGAACA GCAAATCTCT GAAAAGTGAT TTCTACCGTT ACGACATTGA CACTAATACC 
TGGATGTTAC TAAGTGAAGA TACTGCTGCC GACGGTGGAC CAAAGTTGGT GTTTGATCAT 
CAGATGTGTA TGGACTCAGA AAAACATATG ATCTACACGT TTGGTGGCAG GATTTTGACG 
TGTAATGGCA GTGTAGATGA CAGCAGAGCC AGTGAGCCAC AATTCAGTGG GTTGTTTGCG 
TTCAACTGCC AGTGTCAAAC TTGGAAACTT CTTCGAGAGG ATTCCTGTAA TGCTGGCCCT 
GAGGACATCC AGTCTCGGAT TGGACACTGC ATGCTGTTCC ACTCAAAAAA CCGTTGCTTA 
TATGTGTTTG GTGGCCAGAG ATCCAAGACC TATTTGAATG ATTTCTTTAG TTATGATGTG 
GACTCAGATC ATGTAGACAT AATTTCAGAT GGCACCAAGA AAGACTCTGG AATGGTTCCA 
ATGACCGGAT TCACACAGAG AGCAACTATT GATCCAGAAC TGAATGAAAT ACATGTCTTA 
TCCGGACTTA GCAAAGACAA AGAAAAGAGG GAAGAGAATG TCAGAAATTC ATTCTGGATT 
TATGACATTG TGAGGAATAG CTGGTCTTGT GTCTATAAGA ATGATCAAGC TACAAAAGAT 
AATCTGAGTA AAAGTCTTCA GGAGGAAGAA CCATGTCCAA GGTTTGCCCA TCAACTCGTT 
TATGATGAAT TACACAAGGT TCATTATTTA TTTGGTGGAA ATCCAGGAAA ATCTTGCTCT 
CCAAAGATGA GACTAGATGA CTTCTGGTCA CTGAAGTTGT GTAGACCTTC AAAAGACTAC 
TTACTGAGGC ATTGCAAGTA CCTCATAAGA AAACACAGGT TTGAAGAAAA GGCCCAAATG 
GATCCCCTTA GTGCTCTGAA GTATTTACAA AATGATCTTT ATATAACTGT GGATCATTCG 
GACCCAGAAG AGACAAAAGA GTTTCAACTC CTAGCCTCAG CTCTGTTCAA ATCTGGCTCA 
GATTTCACAG CTCTAGGCTT TTCAGATGTG GATCATACCT ATGCTCAAAG AACTCAGCTC 
TTTGACACCT TAGTAAATTT CTTTCCTGAC AGCATGACTC CTCCTAAAGG CAACCTGGTA 
GACCTGATCA CACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mkln1 ( NM_013791.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038819.1 Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), mRNA.

Price & Availability↑

CloneID	OMu20775
Clone ID Related Accession (Same CDS sequence)	NM_013791.2
Accession Version	NM_013791.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	muskelin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD550341.1, AK077541.1, AK136123.1, CF161946.1, AV321114.1 and AC153837.4. On Dec 19, 2006 this sequence version replaced NM_013791.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U72194.1, SRR1660815.214643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCTG GCGGGGCTGT TGCTGTGGCG CCGGAGTGCC GGCTTCTGCC CTACGCGCTG 
CATAAGTGGA GCTCCTTCTC CTCCACCTAC CTTCCCGAGA ACATTTTAGT GGATAAACCA 
AATGATCAGT CTTCCAGATG GTCTTCAGAG AGCAACTATC CTCCCCAATA CTTGATTCTG 
AAGCTTGAAA GGCCTGCTAT CGTTCAGAAT ATTACATTTG GAAAATATGA GAAAACTCAT 
GTCTGCAATT TGAAGAAATT CAAAGTTTTT GGTGGAATGA ATGAAGAAAA TATGACAGAG 
CTGTTGTCCA GTGGCCTGAA GAATGATTAT AACAAAGAGA CATTTACCTT GAAACATAAA 
ATTGATGAAC AGATGTTCCC TTGTCGATTC ATTAAAATTG TTCCACTTTT GTCCTGGGGG 
CCCAGCTTTA ACTTTAGCAT CTGGTATGTT GAACTTAGTG GCATTGATGA TCCTGATATC 
GTGCAGCCCT GTCTGAACTG GTACAGCAAG TACCGTGAAC AGGAAGCCAT TCGCCTTTGC 
CTAAAACACT TCAGACAACA TAACTATACA GAGGCTTTTG AATCCCTGCA GAAGAAAACC 
AAGATTGCAC TGGAACATCC AATGTTGACA GATATGCATG ACAAATTGGT GTTAAAGGGT 
GACTTTGATG CTTGCGAGGA GTTGATTGAA AAAGCTGTAA ATGATGGCTT GTTCAATCAG 
TATATCAGTC AACAGGAGTA TAAGCCACGG TGGAGTCAGA TTATTCCTAA GAGCACCAAA 
GGCGATGGAG AAGATAACAG ACCAGGAATG AGAGGGGGCC ATCAAATGGT CATTGACGTC 
CAGACAGAGA CTGTTTATTT GTTTGGTGGC TGGGATGGAA CACAAGATCT TGCTGACTTC 
TGGGCATACA GTGTGAAGGA GAACCAGTGG ACATGTATTT CTAGAGACAC TGAGAAAGAG 
AATGGTCCGA GTGCCAGATC GTGTCATAAG ATGTGCATTG ACATTCAGCG GAGACAAATC 
TACACATTGG GCCGTTACTT GGATTCCTCT GTGAGGAACA GCAAATCTCT GAAAAGTGAT 
TTCTACCGTT ACGACATTGA CACTAATACC TGGATGTTAC TAAGTGAAGA TACTGCTGCC 
GACGGTGGAC CAAAGTTGGT GTTTGATCAT CAGATGTGTA TGGACTCAGA AAAACATATG 
ATCTACACGT TTGGTGGCAG GATTTTGACG TGTAATGGCA GTGTAGATGA CAGCAGAGCC 
AGTGAGCCAC AATTCAGTGG GTTGTTTGCG TTCAACTGCC AGTGTCAAAC TTGGAAACTT 
CTTCGAGAGG ATTCCTGTAA TGCTGGCCCT GAGGACATCC AGTCTCGGAT TGGACACTGC 
ATGCTGTTCC ACTCAAAAAA CCGTTGCTTA TATGTGTTTG GTGGCCAGAG ATCCAAGACC 
TATTTGAATG ATTTCTTTAG TTATGATGTG GACTCAGATC ATGTAGACAT AATTTCAGAT 
GGCACCAAGA AAGACTCTGG AATGGTTCCA ATGACCGGAT TCACACAGAG AGCAACTATT 
GATCCAGAAC TGAATGAAAT ACATGTCTTA TCCGGACTTA GCAAAGACAA AGAAAAGAGG 
GAAGAGAATG TCAGAAATTC ATTCTGGATT TATGACATTG TGAGGAATAG CTGGTCTTGT 
GTCTATAAGA ATGATCAAGC TACAAAAGAT AATCTGAGTA AAAGTCTTCA GGAGGAAGAA 
CCATGTCCAA GGTTTGCCCA TCAACTCGTT TATGATGAAT TACACAAGGT TCATTATTTA 
TTTGGTGGAA ATCCAGGAAA ATCTTGCTCT CCAAAGATGA GACTAGATGA CTTCTGGTCA 
CTGAAGTTGT GTAGACCTTC AAAAGACTAC TTACTGAGGC ATTGCAAGTA CCTCATAAGA 
AAACACAGGT TTGAAGAAAA GGCCCAAATG GATCCCCTTA GTGCTCTGAA GTATTTACAA 
AATGATCTTT ATATAACTGT GGATCATTCG GACCCAGAAG AGACAAAAGA GTTTCAACTC 
CTAGCCTCAG CTCTGTTCAA ATCTGGCTCA GATTTCACAG CTCTAGGCTT TTCAGATGTG 
GATCATACCT ATGCTCAAAG AACTCAGCTC TTTGACACCT TAGTAAATTT CTTTCCTGAC 
AGCATGACTC CTCCTAAAGG CAACCTGGTA GACCTGATCA CACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038819.1
CDS	30..2237
Translation	MAAGGAVAVAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDMHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL

Target ORF information:

RefSeq Version	NM_013791.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013791.2

ORF Insert Sequence:

ATGGCGGCTG GCGGGGCTGT TGCTGTGGCG CCGGAGTGCC GGCTTCTGCC CTACGCGCTG 
CATAAGTGGA GCTCCTTCTC CTCCACCTAC CTTCCCGAGA ACATTTTAGT GGATAAACCA 
AATGATCAGT CTTCCAGATG GTCTTCAGAG AGCAACTATC CTCCCCAATA CTTGATTCTG 
AAGCTTGAAA GGCCTGCTAT CGTTCAGAAT ATTACATTTG GAAAATATGA GAAAACTCAT 
GTCTGCAATT TGAAGAAATT CAAAGTTTTT GGTGGAATGA ATGAAGAAAA TATGACAGAG 
CTGTTGTCCA GTGGCCTGAA GAATGATTAT AACAAAGAGA CATTTACCTT GAAACATAAA 
ATTGATGAAC AGATGTTCCC TTGTCGATTC ATTAAAATTG TTCCACTTTT GTCCTGGGGG 
CCCAGCTTTA ACTTTAGCAT CTGGTATGTT GAACTTAGTG GCATTGATGA TCCTGATATC 
GTGCAGCCCT GTCTGAACTG GTACAGCAAG TACCGTGAAC AGGAAGCCAT TCGCCTTTGC 
CTAAAACACT TCAGACAACA TAACTATACA GAGGCTTTTG AATCCCTGCA GAAGAAAACC 
AAGATTGCAC TGGAACATCC AATGTTGACA GATATGCATG ACAAATTGGT GTTAAAGGGT 
GACTTTGATG CTTGCGAGGA GTTGATTGAA AAAGCTGTAA ATGATGGCTT GTTCAATCAG 
TATATCAGTC AACAGGAGTA TAAGCCACGG TGGAGTCAGA TTATTCCTAA GAGCACCAAA 
GGCGATGGAG AAGATAACAG ACCAGGAATG AGAGGGGGCC ATCAAATGGT CATTGACGTC 
CAGACAGAGA CTGTTTATTT GTTTGGTGGC TGGGATGGAA CACAAGATCT TGCTGACTTC 
TGGGCATACA GTGTGAAGGA GAACCAGTGG ACATGTATTT CTAGAGACAC TGAGAAAGAG 
AATGGTCCGA GTGCCAGATC GTGTCATAAG ATGTGCATTG ACATTCAGCG GAGACAAATC 
TACACATTGG GCCGTTACTT GGATTCCTCT GTGAGGAACA GCAAATCTCT GAAAAGTGAT 
TTCTACCGTT ACGACATTGA CACTAATACC TGGATGTTAC TAAGTGAAGA TACTGCTGCC 
GACGGTGGAC CAAAGTTGGT GTTTGATCAT CAGATGTGTA TGGACTCAGA AAAACATATG 
ATCTACACGT TTGGTGGCAG GATTTTGACG TGTAATGGCA GTGTAGATGA CAGCAGAGCC 
AGTGAGCCAC AATTCAGTGG GTTGTTTGCG TTCAACTGCC AGTGTCAAAC TTGGAAACTT 
CTTCGAGAGG ATTCCTGTAA TGCTGGCCCT GAGGACATCC AGTCTCGGAT TGGACACTGC 
ATGCTGTTCC ACTCAAAAAA CCGTTGCTTA TATGTGTTTG GTGGCCAGAG ATCCAAGACC 
TATTTGAATG ATTTCTTTAG TTATGATGTG GACTCAGATC ATGTAGACAT AATTTCAGAT 
GGCACCAAGA AAGACTCTGG AATGGTTCCA ATGACCGGAT TCACACAGAG AGCAACTATT 
GATCCAGAAC TGAATGAAAT ACATGTCTTA TCCGGACTTA GCAAAGACAA AGAAAAGAGG 
GAAGAGAATG TCAGAAATTC ATTCTGGATT TATGACATTG TGAGGAATAG CTGGTCTTGT 
GTCTATAAGA ATGATCAAGC TACAAAAGAT AATCTGAGTA AAAGTCTTCA GGAGGAAGAA 
CCATGTCCAA GGTTTGCCCA TCAACTCGTT TATGATGAAT TACACAAGGT TCATTATTTA 
TTTGGTGGAA ATCCAGGAAA ATCTTGCTCT CCAAAGATGA GACTAGATGA CTTCTGGTCA 
CTGAAGTTGT GTAGACCTTC AAAAGACTAC TTACTGAGGC ATTGCAAGTA CCTCATAAGA 
AAACACAGGT TTGAAGAAAA GGCCCAAATG GATCCCCTTA GTGCTCTGAA GTATTTACAA 
AATGATCTTT ATATAACTGT GGATCATTCG GACCCAGAAG AGACAAAAGA GTTTCAACTC 
CTAGCCTCAG CTCTGTTCAA ATCTGGCTCA GATTTCACAG CTCTAGGCTT TTCAGATGTG 
GATCATACCT ATGCTCAAAG AACTCAGCTC TTTGACACCT TAGTAAATTT CTTTCCTGAC 
AGCATGACTC CTCCTAAAGG CAACCTGGTA GACCTGATCA CACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mkln1 ( XM_017321605.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017177094.1 Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu69289
Clone ID Related Accession (Same CDS sequence)	XM_017321605.2 , XM_017321605.1
Accession Version	XM_017321605.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1587bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	muskelin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017321605.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACAG ATATGCATGA CAAATTGGTG TTAAAGGGTG ACTTTGATGC TTGCGAGGAG 
TTGATTGAAA AAGCTGTAAA TGATGGCTTG TTCAATCAGT ATATCAGTCA ACAGGAGTAT 
AAGCCACGGT GGAGTCAGAT TATTCCTAAG AGCACCAAAG GCGATGGAGA AGATAACAGA 
CCAGGAATGA GAGGGGGCCA TCAAATGGTC ATTGACGTCC AGACAGAGAC TGTTTATTTG 
TTTGGTGGCT GGGATGGAAC ACAAGATCTT GCTGACTTCT GGGCATACAG TGTGAAGGAG 
AACCAGTGGA CATGTATTTC TAGAGACACT GAGAAAGAGA ATGGTCCGAG TGCCAGATCG 
TGTCATAAGA TGTGCATTGA CATTCAGCGG AGACAAATCT ACACATTGGG CCGTTACTTG 
GATTCCTCTG TGAGGAACAG CAAATCTCTG AAAAGTGATT TCTACCGTTA CGACATTGAC 
ACTAATACCT GGATGTTACT AAGTGAAGAT ACTGCTGCCG ACGGTGGACC AAAGTTGGTG 
TTTGATCATC AGATGTGTAT GGACTCAGAA AAACATATGA TCTACACGTT TGGTGGCAGG 
ATTTTGACGT GTAATGGCAG TGTAGATGAC AGCAGAGCCA GTGAGCCACA ATTCAGTGGG 
TTGTTTGCGT TCAACTGCCA GTGTCAAACT TGGAAACTTC TTCGAGAGGA TTCCTGTAAT 
GCTGGCCCTG AGGACATCCA GTCTCGGATT GGACACTGCA TGCTGTTCCA CTCAAAAAAC 
CGTTGCTTAT ATGTGTTTGG TGGCCAGAGA TCCAAGACCT ATTTGAATGA TTTCTTTAGT 
TATGATGTGG ACTCAGATCA TGTAGACATA ATTTCAGATG GCACCAAGAA AGACTCTGGA 
ATGGTTCCAA TGACCGGATT CACACAGAGA GCAACTATTG ATCCAGAACT GAATGAAATA 
CATGTCTTAT CCGGACTTAG CAAAGACAAA GAAAAGAGGG AAGAGAATGT CAGAAATTCA 
TTCTGGATTT ATGACATTGT GAGGAATAGC TGGTCTTGTG TCTATAAGAA TGATCAAGCT 
ACAAAAGATA ATCTGAGTAA AAGTCTTCAG GAGGAAGAAC CATGTCCAAG GTTTGCCCAT 
CAACTCGTTT ATGATGAATT ACACAAGGTT CATTATTTAT TTGGTGGAAA TCCAGGAAAA 
TCTTGCTCTC CAAAGATGAG ACTAGATGAC TTCTGGTCAC TGAAGTTGTG TAGACCTTCA 
AAAGACTACT TACTGAGGCA TTGCAAGTAC CTCATAAGAA AACACAGGTT TGAAGAAAAG 
GCCCAAATGG ATCCCCTTAG TGCTCTGAAG TATTTACAAA ATGATCTTTA TATAACTGTG 
GATCATTCGG ACCCAGAAGA GACAAAAGAG TTTCAACTCC TAGCCTCAGC TCTGTTCAAA 
TCTGGCTCAG ATTTCACAGC TCTAGGCTTT TCAGATGTGG ATCATACCTA TGCTCAAAGA 
ACTCAGCTCT TTGACACCTT AGTAAATTTC TTTCCTGACA GCATGACTCC TCCTAAAGGC 
AACCTGGTAG ACCTGATCAC ACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017177094.1
CDS	634..2220
Translation	MLTDMHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL

Target ORF information:

RefSeq Version	XM_017321605.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017321605.2

ORF Insert Sequence:

ATGTTGACAG ATATGCATGA CAAATTGGTG TTAAAGGGTG ACTTTGATGC TTGCGAGGAG 
TTGATTGAAA AAGCTGTAAA TGATGGCTTG TTCAATCAGT ATATCAGTCA ACAGGAGTAT 
AAGCCACGGT GGAGTCAGAT TATTCCTAAG AGCACCAAAG GCGATGGAGA AGATAACAGA 
CCAGGAATGA GAGGGGGCCA TCAAATGGTC ATTGACGTCC AGACAGAGAC TGTTTATTTG 
TTTGGTGGCT GGGATGGAAC ACAAGATCTT GCTGACTTCT GGGCATACAG TGTGAAGGAG 
AACCAGTGGA CATGTATTTC TAGAGACACT GAGAAAGAGA ATGGTCCGAG TGCCAGATCG 
TGTCATAAGA TGTGCATTGA CATTCAGCGG AGACAAATCT ACACATTGGG CCGTTACTTG 
GATTCCTCTG TGAGGAACAG CAAATCTCTG AAAAGTGATT TCTACCGTTA CGACATTGAC 
ACTAATACCT GGATGTTACT AAGTGAAGAT ACTGCTGCCG ACGGTGGACC AAAGTTGGTG 
TTTGATCATC AGATGTGTAT GGACTCAGAA AAACATATGA TCTACACGTT TGGTGGCAGG 
ATTTTGACGT GTAATGGCAG TGTAGATGAC AGCAGAGCCA GTGAGCCACA ATTCAGTGGG 
TTGTTTGCGT TCAACTGCCA GTGTCAAACT TGGAAACTTC TTCGAGAGGA TTCCTGTAAT 
GCTGGCCCTG AGGACATCCA GTCTCGGATT GGACACTGCA TGCTGTTCCA CTCAAAAAAC 
CGTTGCTTAT ATGTGTTTGG TGGCCAGAGA TCCAAGACCT ATTTGAATGA TTTCTTTAGT 
TATGATGTGG ACTCAGATCA TGTAGACATA ATTTCAGATG GCACCAAGAA AGACTCTGGA 
ATGGTTCCAA TGACCGGATT CACACAGAGA GCAACTATTG ATCCAGAACT GAATGAAATA 
CATGTCTTAT CCGGACTTAG CAAAGACAAA GAAAAGAGGG AAGAGAATGT CAGAAATTCA 
TTCTGGATTT ATGACATTGT GAGGAATAGC TGGTCTTGTG TCTATAAGAA TGATCAAGCT 
ACAAAAGATA ATCTGAGTAA AAGTCTTCAG GAGGAAGAAC CATGTCCAAG GTTTGCCCAT 
CAACTCGTTT ATGATGAATT ACACAAGGTT CATTATTTAT TTGGTGGAAA TCCAGGAAAA 
TCTTGCTCTC CAAAGATGAG ACTAGATGAC TTCTGGTCAC TGAAGTTGTG TAGACCTTCA 
AAAGACTACT TACTGAGGCA TTGCAAGTAC CTCATAAGAA AACACAGGTT TGAAGAAAAG 
GCCCAAATGG ATCCCCTTAG TGCTCTGAAG TATTTACAAA ATGATCTTTA TATAACTGTG 
GATCATTCGG ACCCAGAAGA GACAAAAGAG TTTCAACTCC TAGCCTCAGC TCTGTTCAAA 
TCTGGCTCAG ATTTCACAGC TCTAGGCTTT TCAGATGTGG ATCATACCTA TGCTCAAAGA 
ACTCAGCTCT TTGACACCTT AGTAAATTTC TTTCCTGACA GCATGACTCC TCCTAAAGGC 
AACCTGGTAG ACCTGATCAC ACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mkln1 ( XM_017321605.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017177094.1 Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69289
Clone ID Related Accession (Same CDS sequence)	XM_017321605.2 , XM_017321605.1
Accession Version	XM_017321605.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1587bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	muskelin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACAG ATATGCATGA CAAATTGGTG TTAAAGGGTG ACTTTGATGC TTGCGAGGAG 
TTGATTGAAA AAGCTGTAAA TGATGGCTTG TTCAATCAGT ATATCAGTCA ACAGGAGTAT 
AAGCCACGGT GGAGTCAGAT TATTCCTAAG AGCACCAAAG GCGATGGAGA AGATAACAGA 
CCAGGAATGA GAGGGGGCCA TCAAATGGTC ATTGACGTCC AGACAGAGAC TGTTTATTTG 
TTTGGTGGCT GGGATGGAAC ACAAGATCTT GCTGACTTCT GGGCATACAG TGTGAAGGAG 
AACCAGTGGA CATGTATTTC TAGAGACACT GAGAAAGAGA ATGGTCCGAG TGCCAGATCG 
TGTCATAAGA TGTGCATTGA CATTCAGCGG AGACAAATCT ACACATTGGG CCGTTACTTG 
GATTCCTCTG TGAGGAACAG CAAATCTCTG AAAAGTGATT TCTACCGTTA CGACATTGAC 
ACTAATACCT GGATGTTACT AAGTGAAGAT ACTGCTGCCG ACGGTGGACC AAAGTTGGTG 
TTTGATCATC AGATGTGTAT GGACTCAGAA AAACATATGA TCTACACGTT TGGTGGCAGG 
ATTTTGACGT GTAATGGCAG TGTAGATGAC AGCAGAGCCA GTGAGCCACA ATTCAGTGGG 
TTGTTTGCGT TCAACTGCCA GTGTCAAACT TGGAAACTTC TTCGAGAGGA TTCCTGTAAT 
GCTGGCCCTG AGGACATCCA GTCTCGGATT GGACACTGCA TGCTGTTCCA CTCAAAAAAC 
CGTTGCTTAT ATGTGTTTGG TGGCCAGAGA TCCAAGACCT ATTTGAATGA TTTCTTTAGT 
TATGATGTGG ACTCAGATCA TGTAGACATA ATTTCAGATG GCACCAAGAA AGACTCTGGA 
ATGGTTCCAA TGACCGGATT CACACAGAGA GCAACTATTG ATCCAGAACT GAATGAAATA 
CATGTCTTAT CCGGACTTAG CAAAGACAAA GAAAAGAGGG AAGAGAATGT CAGAAATTCA 
TTCTGGATTT ATGACATTGT GAGGAATAGC TGGTCTTGTG TCTATAAGAA TGATCAAGCT 
ACAAAAGATA ATCTGAGTAA AAGTCTTCAG GAGGAAGAAC CATGTCCAAG GTTTGCCCAT 
CAACTCGTTT ATGATGAATT ACACAAGGTT CATTATTTAT TTGGTGGAAA TCCAGGAAAA 
TCTTGCTCTC CAAAGATGAG ACTAGATGAC TTCTGGTCAC TGAAGTTGTG TAGACCTTCA 
AAAGACTACT TACTGAGGCA TTGCAAGTAC CTCATAAGAA AACACAGGTT TGAAGAAAAG 
GCCCAAATGG ATCCCCTTAG TGCTCTGAAG TATTTACAAA ATGATCTTTA TATAACTGTG 
GATCATTCGG ACCCAGAAGA GACAAAAGAG TTTCAACTCC TAGCCTCAGC TCTGTTCAAA 
TCTGGCTCAG ATTTCACAGC TCTAGGCTTT TCAGATGTGG ATCATACCTA TGCTCAAAGA 
ACTCAGCTCT TTGACACCTT AGTAAATTTC TTTCCTGACA GCATGACTCC TCCTAAAGGC 
AACCTGGTAG ACCTGATCAC ACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017177094.1
CDS	527..2113
Translation	MLTDMHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL

Target ORF information:

RefSeq Version	XM_017321605.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017321605.1

ORF Insert Sequence:

ATGTTGACAG ATATGCATGA CAAATTGGTG TTAAAGGGTG ACTTTGATGC TTGCGAGGAG 
TTGATTGAAA AAGCTGTAAA TGATGGCTTG TTCAATCAGT ATATCAGTCA ACAGGAGTAT 
AAGCCACGGT GGAGTCAGAT TATTCCTAAG AGCACCAAAG GCGATGGAGA AGATAACAGA 
CCAGGAATGA GAGGGGGCCA TCAAATGGTC ATTGACGTCC AGACAGAGAC TGTTTATTTG 
TTTGGTGGCT GGGATGGAAC ACAAGATCTT GCTGACTTCT GGGCATACAG TGTGAAGGAG 
AACCAGTGGA CATGTATTTC TAGAGACACT GAGAAAGAGA ATGGTCCGAG TGCCAGATCG 
TGTCATAAGA TGTGCATTGA CATTCAGCGG AGACAAATCT ACACATTGGG CCGTTACTTG 
GATTCCTCTG TGAGGAACAG CAAATCTCTG AAAAGTGATT TCTACCGTTA CGACATTGAC 
ACTAATACCT GGATGTTACT AAGTGAAGAT ACTGCTGCCG ACGGTGGACC AAAGTTGGTG 
TTTGATCATC AGATGTGTAT GGACTCAGAA AAACATATGA TCTACACGTT TGGTGGCAGG 
ATTTTGACGT GTAATGGCAG TGTAGATGAC AGCAGAGCCA GTGAGCCACA ATTCAGTGGG 
TTGTTTGCGT TCAACTGCCA GTGTCAAACT TGGAAACTTC TTCGAGAGGA TTCCTGTAAT 
GCTGGCCCTG AGGACATCCA GTCTCGGATT GGACACTGCA TGCTGTTCCA CTCAAAAAAC 
CGTTGCTTAT ATGTGTTTGG TGGCCAGAGA TCCAAGACCT ATTTGAATGA TTTCTTTAGT 
TATGATGTGG ACTCAGATCA TGTAGACATA ATTTCAGATG GCACCAAGAA AGACTCTGGA 
ATGGTTCCAA TGACCGGATT CACACAGAGA GCAACTATTG ATCCAGAACT GAATGAAATA 
CATGTCTTAT CCGGACTTAG CAAAGACAAA GAAAAGAGGG AAGAGAATGT CAGAAATTCA 
TTCTGGATTT ATGACATTGT GAGGAATAGC TGGTCTTGTG TCTATAAGAA TGATCAAGCT 
ACAAAAGATA ATCTGAGTAA AAGTCTTCAG GAGGAAGAAC CATGTCCAAG GTTTGCCCAT 
CAACTCGTTT ATGATGAATT ACACAAGGTT CATTATTTAT TTGGTGGAAA TCCAGGAAAA 
TCTTGCTCTC CAAAGATGAG ACTAGATGAC TTCTGGTCAC TGAAGTTGTG TAGACCTTCA 
AAAGACTACT TACTGAGGCA TTGCAAGTAC CTCATAAGAA AACACAGGTT TGAAGAAAAG 
GCCCAAATGG ATCCCCTTAG TGCTCTGAAG TATTTACAAA ATGATCTTTA TATAACTGTG 
GATCATTCGG ACCCAGAAGA GACAAAAGAG TTTCAACTCC TAGCCTCAGC TCTGTTCAAA 
TCTGGCTCAG ATTTCACAGC TCTAGGCTTT TCAGATGTGG ATCATACCTA TGCTCAAAGA 
ACTCAGCTCT TTGACACCTT AGTAAATTTC TTTCCTGACA GCATGACTCC TCCTAAAGGC 
AACCTGGTAG ACCTGATCAC ACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mkln1 ( XM_030255436.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030111296.1 Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu89220
Clone ID Related Accession (Same CDS sequence)	XM_030255436.1
Accession Version	XM_030255436.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1932bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	muskelin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGAAG AAAATATGAC AGAGCTGTTG TCCAGTGGCC TGAAGAATGA TTATAACAAA 
GAGACATTTA CCTTGAAACA TAAAATTGAT GAACAGATGT TCCCTTGTCG ATTCATTAAA 
ATTGTTCCAC TTTTGTCCTG GGGGCCCAGC TTTAACTTTA GCATCTGGTA TGTTGAACTT 
AGTGGCATTG ATGATCCTGA TATCGTGCAG CCCTGTCTGA ACTGGTACAG CAAGTACCGT 
GAACAGGAAG CCATTCGCCT TTGCCTAAAA CACTTCAGAC AACATAACTA TACAGAGGCT 
TTTGAATCCC TGCAGAAGAA AACCAAGATT GCACTGGAAC ATCCAATGTT GACAGATATG 
CATGACAAAT TGGTGTTAAA GGGTGACTTT GATGCTTGCG AGGAGTTGAT TGAAAAAGCT 
GTAAATGATG GCTTGTTCAA TCAGTATATC AGTCAACAGG AGTATAAGCC ACGGTGGAGT 
CAGATTATTC CTAAGAGCAC CAAAGGCGAT GGAGAAGATA ACAGACCAGG AATGAGAGGG 
GGCCATCAAA TGGTCATTGA CGTCCAGACA GAGACTGTTT ATTTGTTTGG TGGCTGGGAT 
GGAACACAAG ATCTTGCTGA CTTCTGGGCA TACAGTGTGA AGGAGAACCA GTGGACATGT 
ATTTCTAGAG ACACTGAGAA AGAGAATGGT CCGAGTGCCA GATCGTGTCA TAAGATGTGC 
ATTGACATTC AGCGGAGACA AATCTACACA TTGGGCCGTT ACTTGGATTC CTCTGTGAGG 
AACAGCAAAT CTCTGAAAAG TGATTTCTAC CGTTACGACA TTGACACTAA TACCTGGATG 
TTACTAAGTG AAGATACTGC TGCCGACGGT GGACCAAAGT TGGTGTTTGA TCATCAGATG 
TGTATGGACT CAGAAAAACA TATGATCTAC ACGTTTGGTG GCAGGATTTT GACGTGTAAT 
GGCAGTGTAG ATGACAGCAG AGCCAGTGAG CCACAATTCA GTGGGTTGTT TGCGTTCAAC 
TGCCAGTGTC AAACTTGGAA ACTTCTTCGA GAGGATTCCT GTAATGCTGG CCCTGAGGAC 
ATCCAGTCTC GGATTGGACA CTGCATGCTG TTCCACTCAA AAAACCGTTG CTTATATGTG 
TTTGGTGGCC AGAGATCCAA GACCTATTTG AATGATTTCT TTAGTTATGA TGTGGACTCA 
GATCATGTAG ACATAATTTC AGATGGCACC AAGAAAGACT CTGGAATGGT TCCAATGACC 
GGATTCACAC AGAGAGCAAC TATTGATCCA GAACTGAATG AAATACATGT CTTATCCGGA 
CTTAGCAAAG ACAAAGAAAA GAGGGAAGAG AATGTCAGAA ATTCATTCTG GATTTATGAC 
ATTGTGAGGA ATAGCTGGTC TTGTGTCTAT AAGAATGATC AAGCTACAAA AGATAATCTG 
AGTAAAAGTC TTCAGGAGGA AGAACCATGT CCAAGGTTTG CCCATCAACT CGTTTATGAT 
GAATTACACA AGGTTCATTA TTTATTTGGT GGAAATCCAG GAAAATCTTG CTCTCCAAAG 
ATGAGACTAG ATGACTTCTG GTCACTGAAG TTGTGTAGAC CTTCAAAAGA CTACTTACTG 
AGGCATTGCA AGTACCTCAT AAGAAAACAC AGGTTTGAAG AAAAGGCCCA AATGGATCCC 
CTTAGTGCTC TGAAGTATTT ACAAAATGAT CTTTATATAA CTGTGGATCA TTCGGACCCA 
GAAGAGACAA AAGAGTTTCA ACTCCTAGCC TCAGCTCTGT TCAAATCTGG CTCAGATTTC 
ACAGCTCTAG GCTTTTCAGA TGTGGATCAT ACCTATGCTC AAAGAACTCA GCTCTTTGAC 
ACCTTAGTAA ATTTCTTTCC TGACAGCATG ACTCCTCCTA AAGGCAACCT GGTAGACCTG 
ATCACACTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030111296.1
CDS	510..2441
Translation	MNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDMHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQATKDNLSKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL

Target ORF information:

RefSeq Version	XM_030255436.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus muskelin 1, intracellular mediator containing kelch motifs (Mkln1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030255436.1

ORF Insert Sequence:

ATGAATGAAG AAAATATGAC AGAGCTGTTG TCCAGTGGCC TGAAGAATGA TTATAACAAA 
GAGACATTTA CCTTGAAACA TAAAATTGAT GAACAGATGT TCCCTTGTCG ATTCATTAAA 
ATTGTTCCAC TTTTGTCCTG GGGGCCCAGC TTTAACTTTA GCATCTGGTA TGTTGAACTT 
AGTGGCATTG ATGATCCTGA TATCGTGCAG CCCTGTCTGA ACTGGTACAG CAAGTACCGT 
GAACAGGAAG CCATTCGCCT TTGCCTAAAA CACTTCAGAC AACATAACTA TACAGAGGCT 
TTTGAATCCC TGCAGAAGAA AACCAAGATT GCACTGGAAC ATCCAATGTT GACAGATATG 
CATGACAAAT TGGTGTTAAA GGGTGACTTT GATGCTTGCG AGGAGTTGAT TGAAAAAGCT 
GTAAATGATG GCTTGTTCAA TCAGTATATC AGTCAACAGG AGTATAAGCC ACGGTGGAGT 
CAGATTATTC CTAAGAGCAC CAAAGGCGAT GGAGAAGATA ACAGACCAGG AATGAGAGGG 
GGCCATCAAA TGGTCATTGA CGTCCAGACA GAGACTGTTT ATTTGTTTGG TGGCTGGGAT 
GGAACACAAG ATCTTGCTGA CTTCTGGGCA TACAGTGTGA AGGAGAACCA GTGGACATGT 
ATTTCTAGAG ACACTGAGAA AGAGAATGGT CCGAGTGCCA GATCGTGTCA TAAGATGTGC 
ATTGACATTC AGCGGAGACA AATCTACACA TTGGGCCGTT ACTTGGATTC CTCTGTGAGG 
AACAGCAAAT CTCTGAAAAG TGATTTCTAC CGTTACGACA TTGACACTAA TACCTGGATG 
TTACTAAGTG AAGATACTGC TGCCGACGGT GGACCAAAGT TGGTGTTTGA TCATCAGATG 
TGTATGGACT CAGAAAAACA TATGATCTAC ACGTTTGGTG GCAGGATTTT GACGTGTAAT 
GGCAGTGTAG ATGACAGCAG AGCCAGTGAG CCACAATTCA GTGGGTTGTT TGCGTTCAAC 
TGCCAGTGTC AAACTTGGAA ACTTCTTCGA GAGGATTCCT GTAATGCTGG CCCTGAGGAC 
ATCCAGTCTC GGATTGGACA CTGCATGCTG TTCCACTCAA AAAACCGTTG CTTATATGTG 
TTTGGTGGCC AGAGATCCAA GACCTATTTG AATGATTTCT TTAGTTATGA TGTGGACTCA 
GATCATGTAG ACATAATTTC AGATGGCACC AAGAAAGACT CTGGAATGGT TCCAATGACC 
GGATTCACAC AGAGAGCAAC TATTGATCCA GAACTGAATG AAATACATGT CTTATCCGGA 
CTTAGCAAAG ACAAAGAAAA GAGGGAAGAG AATGTCAGAA ATTCATTCTG GATTTATGAC 
ATTGTGAGGA ATAGCTGGTC TTGTGTCTAT AAGAATGATC AAGCTACAAA AGATAATCTG 
AGTAAAAGTC TTCAGGAGGA AGAACCATGT CCAAGGTTTG CCCATCAACT CGTTTATGAT 
GAATTACACA AGGTTCATTA TTTATTTGGT GGAAATCCAG GAAAATCTTG CTCTCCAAAG 
ATGAGACTAG ATGACTTCTG GTCACTGAAG TTGTGTAGAC CTTCAAAAGA CTACTTACTG 
AGGCATTGCA AGTACCTCAT AAGAAAACAC AGGTTTGAAG AAAAGGCCCA AATGGATCCC 
CTTAGTGCTC TGAAGTATTT ACAAAATGAT CTTTATATAA CTGTGGATCA TTCGGACCCA 
GAAGAGACAA AAGAGTTTCA ACTCCTAGCC TCAGCTCTGT TCAAATCTGG CTCAGATTTC 
ACAGCTCTAG GCTTTTCAGA TGTGGATCAT ACCTATGCTC AAAGAACTCA GCTCTTTGAC 
ACCTTAGTAA ATTTCTTTCC TGACAGCATG ACTCCTCCTA AAGGCAACCT GGTAGACCTG 
ATCACACTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Muskelin Coordinates PrP
Neuron99(6)1155-1169.e9(2018 09)
Heisler FF,Pechmann Y,Wieser I,Altmeppen HC,Veenendaal L,Muhia M,Schweizer M,Glatzel M,Krasemann S,Kneussel M

The LisH motif of muskelin is crucial for oligomerization and governs intracellular localization.
Structure (London, England : 1993)23(2)364-73(2015 Feb)
Delto CF,Heisler FF,Kuper J,Sander B,Kneussel M,Schindelin H

Structure of mouse muskelin discoidin domain and biochemical characterization of its self-association.
Acta crystallographica. Section D, Biological crystallography70(Pt 11)2863-74(2014 Nov)
Kim KH,Hong SK,Hwang KY,Kim EE

Characterization of the novel interaction between muskelin and TBX20, a critical cardiogenic transcription factor.
Biochemical and biophysical research communications409(2)338-43(2011 Jun)
Debenedittis P,Harmelink C,Chen Y,Wang Q,Jiao K

Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.
Neuron70(1)66-81(2011 Apr)
Heisler FF,Loebrich S,Pechmann Y,Maier N,Zivkovic AR,Tokito M,Hausrat TJ,Schweizer M,Bähring R,Holzbaur EL,Schmitz D,Kneussel M

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Mkln1 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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