A2m cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	A2m
Entrez Gene ID	232345
Full Name	alpha-2-macroglobulin
Synonyms	A2mp
General protein information	Preferred Names alpha-2-macroglobulin Names alpha-2-macroglobulin-P
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 F1\|6 57.49 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_175628.3	NP_783327.2	alpha-2-macroglobulin-P precursor
XM_011241322.1	XP_011239624.1	alpha-2-macroglobulin-P isoform X1
XM_011241322.2	XP_011239624.1	alpha-2-macroglobulin-P isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	a2ml1	XP_697477.6
Danio rerio (zebrafish)	LOC100003785	XP_005157599.1
Danio rerio (zebrafish)	LOC100006782	XP_001345438.5
Danio rerio (zebrafish)	LOC100006895	XP_001923676.1
Danio rerio (zebrafish)	LOC100006925	XP_001921577.3
Danio rerio (zebrafish)	a2ml	NP_001132951.1
Rattus norvegicus (Norway rat)	LOC100911545	XP_003749876.1
Danio rerio (zebrafish)	zgc:171446	NP_001108028.1
Danio rerio (zebrafish)	sb:cb37	XP_001345541.5
Homo sapiens (human)	A2M	NP_000005.2
Macaca mulatta (Rhesus monkey)	A2M	XP_001114328.1
Canis lupus familiaris (dog)	A2M	XP_534893.3
Bos taurus (cattle)	A2M	NP_001103265.1
Danio rerio (zebrafish)	zgc:165453	XP_001918704.3
Danio rerio (zebrafish)	zgc:171426	XP_003198073.1
Pan troglodytes (chimpanzee)	A2M	XP_001139819.1
Danio rerio (zebrafish)	zgc:171445	NP_001107101.1
Mus musculus (house mouse)	A2m	NP_783327.2
Rattus norvegicus (Norway rat)	A2m	NP_036620.2
Gallus gallus (chicken)	A2M	XP_416476.3
Danio rerio (zebrafish)	si:dkey-46g23.5	NP_001188334.1
Danio rerio (zebrafish)	si:dkey-46g23.2	XP_001332356.1
Xenopus tropicalis (tropical clawed frog)	a2m	XP_002938550.2
Danio rerio (zebrafish)	si:dkey-52d15.2	XP_001345569.3
Danio rerio (zebrafish)	zgc:165518	NP_001093623.2
Xenopus tropicalis (tropical clawed frog)	LOC100489060	XP_002938549.2

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.
Shemesh CS, Yu RZ, Gaus HJ, Seth PP, Swayze EE, Bennett FC, Geary RS, Henry SP, Wang Y
Nucleic acid therapeutics26(4)223-35(2016 08)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.
Son EJ, Wu L, Yoon H, Kim S, Choi JY, Bok J
PloS one7(7)e40735(2012)

Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells.
Umans L, Serneels L, Hilliker C, Stas L, Overbergh L, De Strooper B, Van Leuven F, Van den Berghe H
Genomics22(3)519-29(1994 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following A2m gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the A2m cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu73610	XM_011241322.2 Latest version!	Mus musculus alpha-2-macroglobulin (A2m), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu05590	NM_175628.3 Latest version!	Mus musculus alpha-2-macroglobulin (A2m), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
View Old Accession Versions >>
OMu73610	XM_011241322.1	Mus musculus alpha-2-macroglobulin (A2m), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

A2m ( XM_011241322.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239624.1 Mus musculus alpha-2-macroglobulin (A2m), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu73610
Clone ID Related Accession (Same CDS sequence)	XM_011241322.1 , XM_011241322.2
Accession Version	XM_011241322.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	alpha-2-macroglobulin-P isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGC GCTGGCTCCC AAGCCTGGCC CTGCTGCCGC TGCCGCCACC GCTGCTGCTG 
CTGCTGTTGC TGCTGCTGCC CACAAATGCC TCAGCACCAC AGAAACCAAT CTACATGGTG 
ATGGTTCCCT CCCTGCTCCA CGCTGGCACC CCTGAGAAGG GCTGCCTCCT GTTCAACCAC 
CTAAACGAGA CAGTAACAGT GAAAGTATCC ATGGAGTCTG TCCGTGGGAA CCAAAGCCTC 
TTCACTGACC TTGTTGTTGA CAAGGACTTA TTCCACTGTG CCTCCTTCAT CGTCCCACAG 
TCTTCATCCA ATGAGGTGAT GTTTCTCACT GTCCAAGTAA AAGGACCAAC TCATGAGTTC 
AGGAGGAGGA GCACGGTGCT GATCAAGACT AAAGAGAGCC TGGTCTTTGC TCAGACTGAC 
AAGCCCATCT ACAAACCAGG ACAGATGGTG AGATTTCGTG TTGTCTCATT GGACGAAAAT 
TTCCACCCCC TTAATGAATT GATTCCTCTA CTGTACATTC AGGATTCAAA AAAAAATCGC 
ATTGCACAGT GGCAGAATTT CCGCTTAGAG GGTGGCCTCA AACAGCTGTC CTTCCCCCTC 
TCCTCAGAGC CCACTCAGGG CTCCTACAAG GTGGTGATAC GTACAGAATC AGGCAGGACC 
GTCGAGCACC CCTTCTCTGT GAAGGAATTT GTGCTTCCCA AGTTTGAAGT CAAAGTTGCA 
GTACCAGAGA CAATCACCAT CCTGGAGGAA GAGATGAATG TGTCCGTGTG TGGCATATAC 
ACCTATGGGA AGCCTGTTCC AGGACACGTG ACTGTGAACA TTTGCAGAAA GTACAGTAAT 
CCTTCTAGCT GCTTTGGTGA AGAATCGCTG GCTTTCTGTG AGAAATTCAG TCAACAGCTA 
GATGGCCGTG GCTGCTTCTC ACAGCTAGTG AAAACCAAGT CTTTCCAGCT AAAGAGGCAA 
GAGTATGAGA TGCAGCTTGA TGTGAATGCC AAGATCCAAG AAGAAGGAAC AGGTGTGGAA 
GAAACCGGTA AAGGGCTCAC TAAGATCACA AGAACTATAA CAAAACTATC ATTTGTGAAC 
GTGGATACAC ATTTCAGACA AGGAATTCCT TTCGTTGGGC AGGTGCTCCT GGTGGATGGG 
AGAGGCACCC CTATTCCATA TGAAATGATC TTCATTGGAG CTGATGAAGC AAACCAGAAC 
ATAAATACTA CCACTGATAA GAATGGCCTG GCACGGTTCT CCATCAACAC TGATGACATC 
ATGGGCACGT CCCTAACTGT CAGGGCCAAA TACAAAGATA GCAATGTCTG CTATGGATTT 
AGATGGTTGA CAGAAGAGAA CGTAGAGGCT TGGCACACTG CCAACGCTGT CTTCTCACCG 
AGCAGAAGCT TCGTGCACCT GGAATCCCTG CCCTATAAAC TGCGCTGTGA GCAAACCCTG 
GCGGTCCAGG CTCATTATAT TCTAAATGAC GAGGCTGTGC TGGAGCGGAA GGAGTTGGTC 
TTCTATTATC TGATGATGGC AAAGGGAGGC ATTGTTCGGG CAGGGACTCA CGTTCTGCCT 
GTGACGCAGG GACACAAGAA AGGCCATTTC TCCATCCTCA TCTCGATGGA GACAGACCTG 
GCTCCTGTAG CTCGACTGGT CCTTTATACC ATTCTGCCCA ATGGAGAAGT GGTTGGAGAT 
ACTGTTAAAT ATGAGATTGA AAAGTGCCTG GCCAACAAGG TGGATTTGGT CTTCCACCCA 
AATATCGGTC TTCCGGCCAC ACGTGCCTTC CTCAGTGTCA TGGCTTCTCC TCAGTCTCTC 
TGTGGCCTGC GAGCTGTGGA CCAAAGCGTA CTGCTCACAA AGCCTGAGGC CGAACTCTCT 
GCATCCCTGG TTTATGATCT GCTACCAGTG AAAGACCTCA CTGGCTTCCC TAAGGGTGTG 
AATCAACAGG AAGAAGACAC TAATGGCTGC CTTAAGCAAA ATGACACTTA CATTAATGGA 
ATCCTGTACT CCCCAGTACA GAATACAAAT GAAGAGGACA TGTATGGCTT CCTAAAGGAT 
ATGGGCTTAA AGGTATTCAC CAACTTGAAC ATCCGTAAAC CCAAAGTCTG TGAACGCCTT 
GGAGTCAATA AAATACCAGC TGCATACCAC CTTGTAAGCC AAGGCCACAT GGATGCTTTT 
CTAGAGTCTT CAGAGTCTCC CACAGAGACT ACACGAAGCT ACTTCCCTGA GACGTGGATC 
TGGGACTTGG TGATCGTGGA CTCAACAGGA GTGGCTGAAA TGGAAGTGAC AGTCCCTGAC 
ACCATCACTG AATGGAAGGC TGGGGCCTTC TGCCTGTCCA ATGACACTGG GTTGGGCCTC 
TCTCCTGTGA TCGATTTCCA AGCCTTCCAG CCCTTCTTCG TGGATCTCAC AATGCCCTAC 
TCCGTGATCC GTGGAGAGGC CTTCACGCTC AAGGCCACTG TGCTGAACTA CCTCCAGACA 
TGCATCCGGG TTGGTGTACA GCTGGAGGCC TCTCCTGATT TCCTAGCTAC CCCAGAGGAG 
AAGGAACAAA AGTCTCACTG CATCTGTATG AACGAGCGGC ATACCATGTC CTGGGCGGTG 
ATCCCCAAGT CATTAGGAAA TGTGAATTTC ACAGTGAGTG CAGAGGCACT GGACTCTAAG 
GAGCTGTGTA GGAATGAGGT GCCAGTGGTT CCTGAACGTG GAAAGAAAGA CACGATCATC 
AAGTCCCTGC TGGTTGAACC TGAAGGTCTA GAGAATGAAG TGACATTCAA CAGTTTGCTT 
TGTCCAACAG GTGCTGAGCT ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239624.1
CDS	124..2910
Translation	MGKRWLPSLALLPLPPPLLLLLLLLLPTNASAPQKPIYMVMVPSLLHAGTPEKGCLLFNHLNETVTVKVSMESVRGNQSLFTDLVVDKDLFHCASFIVPQSSSNEVMFLTVQVKGPTHEFRRRSTVLIKTKESLVFAQTDKPIYKPGQMVRFRVVSLDENFHPLNELIPLLYIQDSKKNRIAQWQNFRLEGGLKQLSFPLSSEPTQGSYKVVIRTESGRTVEHPFSVKEFVLPKFEVKVAVPETITILEEEMNVSVCGIYTYGKPVPGHVTVNICRKYSNPSSCFGEESLAFCEKFSQQLDGRGCFSQLVKTKSFQLKRQEYEMQLDVNAKIQEEGTGVEETGKGLTKITRTITKLSFVNVDTHFRQGIPFVGQVLLVDGRGTPIPYEMIFIGADEANQNINTTTDKNGLARFSINTDDIMGTSLTVRAKYKDSNVCYGFRWLTEENVEAWHTANAVFSPSRSFVHLESLPYKLRCEQTLAVQAHYILNDEAVLERKELVFYYLMMAKGGIVRAGTHVLPVTQGHKKGHFSILISMETDLAPVARLVLYTILPNGEVVGDTVKYEIEKCLANKVDLVFHPNIGLPATRAFLSVMASPQSLCGLRAVDQSVLLTKPEAELSASLVYDLLPVKDLTGFPKGVNQQEEDTNGCLKQNDTYINGILYSPVQNTNEEDMYGFLKDMGLKVFTNLNIRKPKVCERLGVNKIPAAYHLVSQGHMDAFLESSESPTETTRSYFPETWIWDLVIVDSTGVAEMEVTVPDTITEWKAGAFCLSNDTGLGLSPVIDFQAFQPFFVDLTMPYSVIRGEAFTLKATVLNYLQTCIRVGVQLEASPDFLATPEEKEQKSHCICMNERHTMSWAVIPKSLGNVNFTVSAEALDSKELCRNEVPVVPERGKKDTIIKSLLVEPEGLENEVTFNSLLCPTGAELF

Target ORF information:

RefSeq Version	XM_011241322.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus alpha-2-macroglobulin (A2m), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241322.1

ORF Insert Sequence:

ATGGGGAAGC GCTGGCTCCC AAGCCTGGCC CTGCTGCCGC TGCCGCCACC GCTGCTGCTG 
CTGCTGTTGC TGCTGCTGCC CACAAATGCC TCAGCACCAC AGAAACCAAT CTACATGGTG 
ATGGTTCCCT CCCTGCTCCA CGCTGGCACC CCTGAGAAGG GCTGCCTCCT GTTCAACCAC 
CTAAACGAGA CAGTAACAGT GAAAGTATCC ATGGAGTCTG TCCGTGGGAA CCAAAGCCTC 
TTCACTGACC TTGTTGTTGA CAAGGACTTA TTCCACTGTG CCTCCTTCAT CGTCCCACAG 
TCTTCATCCA ATGAGGTGAT GTTTCTCACT GTCCAAGTAA AAGGACCAAC TCATGAGTTC 
AGGAGGAGGA GCACGGTGCT GATCAAGACT AAAGAGAGCC TGGTCTTTGC TCAGACTGAC 
AAGCCCATCT ACAAACCAGG ACAGATGGTG AGATTTCGTG TTGTCTCATT GGACGAAAAT 
TTCCACCCCC TTAATGAATT GATTCCTCTA CTGTACATTC AGGATTCAAA AAAAAATCGC 
ATTGCACAGT GGCAGAATTT CCGCTTAGAG GGTGGCCTCA AACAGCTGTC CTTCCCCCTC 
TCCTCAGAGC CCACTCAGGG CTCCTACAAG GTGGTGATAC GTACAGAATC AGGCAGGACC 
GTCGAGCACC CCTTCTCTGT GAAGGAATTT GTGCTTCCCA AGTTTGAAGT CAAAGTTGCA 
GTACCAGAGA CAATCACCAT CCTGGAGGAA GAGATGAATG TGTCCGTGTG TGGCATATAC 
ACCTATGGGA AGCCTGTTCC AGGACACGTG ACTGTGAACA TTTGCAGAAA GTACAGTAAT 
CCTTCTAGCT GCTTTGGTGA AGAATCGCTG GCTTTCTGTG AGAAATTCAG TCAACAGCTA 
GATGGCCGTG GCTGCTTCTC ACAGCTAGTG AAAACCAAGT CTTTCCAGCT AAAGAGGCAA 
GAGTATGAGA TGCAGCTTGA TGTGAATGCC AAGATCCAAG AAGAAGGAAC AGGTGTGGAA 
GAAACCGGTA AAGGGCTCAC TAAGATCACA AGAACTATAA CAAAACTATC ATTTGTGAAC 
GTGGATACAC ATTTCAGACA AGGAATTCCT TTCGTTGGGC AGGTGCTCCT GGTGGATGGG 
AGAGGCACCC CTATTCCATA TGAAATGATC TTCATTGGAG CTGATGAAGC AAACCAGAAC 
ATAAATACTA CCACTGATAA GAATGGCCTG GCACGGTTCT CCATCAACAC TGATGACATC 
ATGGGCACGT CCCTAACTGT CAGGGCCAAA TACAAAGATA GCAATGTCTG CTATGGATTT 
AGATGGTTGA CAGAAGAGAA CGTAGAGGCT TGGCACACTG CCAACGCTGT CTTCTCACCG 
AGCAGAAGCT TCGTGCACCT GGAATCCCTG CCCTATAAAC TGCGCTGTGA GCAAACCCTG 
GCGGTCCAGG CTCATTATAT TCTAAATGAC GAGGCTGTGC TGGAGCGGAA GGAGTTGGTC 
TTCTATTATC TGATGATGGC AAAGGGAGGC ATTGTTCGGG CAGGGACTCA CGTTCTGCCT 
GTGACGCAGG GACACAAGAA AGGCCATTTC TCCATCCTCA TCTCGATGGA GACAGACCTG 
GCTCCTGTAG CTCGACTGGT CCTTTATACC ATTCTGCCCA ATGGAGAAGT GGTTGGAGAT 
ACTGTTAAAT ATGAGATTGA AAAGTGCCTG GCCAACAAGG TGGATTTGGT CTTCCACCCA 
AATATCGGTC TTCCGGCCAC ACGTGCCTTC CTCAGTGTCA TGGCTTCTCC TCAGTCTCTC 
TGTGGCCTGC GAGCTGTGGA CCAAAGCGTA CTGCTCACAA AGCCTGAGGC CGAACTCTCT 
GCATCCCTGG TTTATGATCT GCTACCAGTG AAAGACCTCA CTGGCTTCCC TAAGGGTGTG 
AATCAACAGG AAGAAGACAC TAATGGCTGC CTTAAGCAAA ATGACACTTA CATTAATGGA 
ATCCTGTACT CCCCAGTACA GAATACAAAT GAAGAGGACA TGTATGGCTT CCTAAAGGAT 
ATGGGCTTAA AGGTATTCAC CAACTTGAAC ATCCGTAAAC CCAAAGTCTG TGAACGCCTT 
GGAGTCAATA AAATACCAGC TGCATACCAC CTTGTAAGCC AAGGCCACAT GGATGCTTTT 
CTAGAGTCTT CAGAGTCTCC CACAGAGACT ACACGAAGCT ACTTCCCTGA GACGTGGATC 
TGGGACTTGG TGATCGTGGA CTCAACAGGA GTGGCTGAAA TGGAAGTGAC AGTCCCTGAC 
ACCATCACTG AATGGAAGGC TGGGGCCTTC TGCCTGTCCA ATGACACTGG GTTGGGCCTC 
TCTCCTGTGA TCGATTTCCA AGCCTTCCAG CCCTTCTTCG TGGATCTCAC AATGCCCTAC 
TCCGTGATCC GTGGAGAGGC CTTCACGCTC AAGGCCACTG TGCTGAACTA CCTCCAGACA 
TGCATCCGGG TTGGTGTACA GCTGGAGGCC TCTCCTGATT TCCTAGCTAC CCCAGAGGAG 
AAGGAACAAA AGTCTCACTG CATCTGTATG AACGAGCGGC ATACCATGTC CTGGGCGGTG 
ATCCCCAAGT CATTAGGAAA TGTGAATTTC ACAGTGAGTG CAGAGGCACT GGACTCTAAG 
GAGCTGTGTA GGAATGAGGT GCCAGTGGTT CCTGAACGTG GAAAGAAAGA CACGATCATC 
AAGTCCCTGC TGGTTGAACC TGAAGGTCTA GAGAATGAAG TGACATTCAA CAGTTTGCTT 
TGTCCAACAG GTGCTGAGCT ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2m ( XM_011241322.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239624.1 Mus musculus alpha-2-macroglobulin (A2m), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu73610
Clone ID Related Accession (Same CDS sequence)	XM_011241322.1 , XM_011241322.2
Accession Version	XM_011241322.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	alpha-2-macroglobulin-P isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241322.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGC GCTGGCTCCC AAGCCTGGCC CTGCTGCCGC TGCCGCCACC GCTGCTGCTG 
CTGCTGTTGC TGCTGCTGCC CACAAATGCC TCAGCACCAC AGAAACCAAT CTACATGGTG 
ATGGTTCCCT CCCTGCTCCA CGCTGGCACC CCTGAGAAGG GCTGCCTCCT GTTCAACCAC 
CTAAACGAGA CAGTAACAGT GAAAGTATCC ATGGAGTCTG TCCGTGGGAA CCAAAGCCTC 
TTCACTGACC TTGTTGTTGA CAAGGACTTA TTCCACTGTG CCTCCTTCAT CGTCCCACAG 
TCTTCATCCA ATGAGGTGAT GTTTCTCACT GTCCAAGTAA AAGGACCAAC TCATGAGTTC 
AGGAGGAGGA GCACGGTGCT GATCAAGACT AAAGAGAGCC TGGTCTTTGC TCAGACTGAC 
AAGCCCATCT ACAAACCAGG ACAGATGGTG AGATTTCGTG TTGTCTCATT GGACGAAAAT 
TTCCACCCCC TTAATGAATT GATTCCTCTA CTGTACATTC AGGATTCAAA AAAAAATCGC 
ATTGCACAGT GGCAGAATTT CCGCTTAGAG GGTGGCCTCA AACAGCTGTC CTTCCCCCTC 
TCCTCAGAGC CCACTCAGGG CTCCTACAAG GTGGTGATAC GTACAGAATC AGGCAGGACC 
GTCGAGCACC CCTTCTCTGT GAAGGAATTT GTGCTTCCCA AGTTTGAAGT CAAAGTTGCA 
GTACCAGAGA CAATCACCAT CCTGGAGGAA GAGATGAATG TGTCCGTGTG TGGCATATAC 
ACCTATGGGA AGCCTGTTCC AGGACACGTG ACTGTGAACA TTTGCAGAAA GTACAGTAAT 
CCTTCTAGCT GCTTTGGTGA AGAATCGCTG GCTTTCTGTG AGAAATTCAG TCAACAGCTA 
GATGGCCGTG GCTGCTTCTC ACAGCTAGTG AAAACCAAGT CTTTCCAGCT AAAGAGGCAA 
GAGTATGAGA TGCAGCTTGA TGTGAATGCC AAGATCCAAG AAGAAGGAAC AGGTGTGGAA 
GAAACCGGTA AAGGGCTCAC TAAGATCACA AGAACTATAA CAAAACTATC ATTTGTGAAC 
GTGGATACAC ATTTCAGACA AGGAATTCCT TTCGTTGGGC AGGTGCTCCT GGTGGATGGG 
AGAGGCACCC CTATTCCATA TGAAATGATC TTCATTGGAG CTGATGAAGC AAACCAGAAC 
ATAAATACTA CCACTGATAA GAATGGCCTG GCACGGTTCT CCATCAACAC TGATGACATC 
ATGGGCACGT CCCTAACTGT CAGGGCCAAA TACAAAGATA GCAATGTCTG CTATGGATTT 
AGATGGTTGA CAGAAGAGAA CGTAGAGGCT TGGCACACTG CCAACGCTGT CTTCTCACCG 
AGCAGAAGCT TCGTGCACCT GGAATCCCTG CCCTATAAAC TGCGCTGTGA GCAAACCCTG 
GCGGTCCAGG CTCATTATAT TCTAAATGAC GAGGCTGTGC TGGAGCGGAA GGAGTTGGTC 
TTCTATTATC TGATGATGGC AAAGGGAGGC ATTGTTCGGG CAGGGACTCA CGTTCTGCCT 
GTGACGCAGG GACACAAGAA AGGCCATTTC TCCATCCTCA TCTCGATGGA GACAGACCTG 
GCTCCTGTAG CTCGACTGGT CCTTTATACC ATTCTGCCCA ATGGAGAAGT GGTTGGAGAT 
ACTGTTAAAT ATGAGATTGA AAAGTGCCTG GCCAACAAGG TGGATTTGGT CTTCCACCCA 
AATATCGGTC TTCCGGCCAC ACGTGCCTTC CTCAGTGTCA TGGCTTCTCC TCAGTCTCTC 
TGTGGCCTGC GAGCTGTGGA CCAAAGCGTA CTGCTCACAA AGCCTGAGGC CGAACTCTCT 
GCATCCCTGG TTTATGATCT GCTACCAGTG AAAGACCTCA CTGGCTTCCC TAAGGGTGTG 
AATCAACAGG AAGAAGACAC TAATGGCTGC CTTAAGCAAA ATGACACTTA CATTAATGGA 
ATCCTGTACT CCCCAGTACA GAATACAAAT GAAGAGGACA TGTATGGCTT CCTAAAGGAT 
ATGGGCTTAA AGGTATTCAC CAACTTGAAC ATCCGTAAAC CCAAAGTCTG TGAACGCCTT 
GGAGTCAATA AAATACCAGC TGCATACCAC CTTGTAAGCC AAGGCCACAT GGATGCTTTT 
CTAGAGTCTT CAGAGTCTCC CACAGAGACT ACACGAAGCT ACTTCCCTGA GACGTGGATC 
TGGGACTTGG TGATCGTGGA CTCAACAGGA GTGGCTGAAA TGGAAGTGAC AGTCCCTGAC 
ACCATCACTG AATGGAAGGC TGGGGCCTTC TGCCTGTCCA ATGACACTGG GTTGGGCCTC 
TCTCCTGTGA TCGATTTCCA AGCCTTCCAG CCCTTCTTCG TGGATCTCAC AATGCCCTAC 
TCCGTGATCC GTGGAGAGGC CTTCACGCTC AAGGCCACTG TGCTGAACTA CCTCCAGACA 
TGCATCCGGG TTGGTGTACA GCTGGAGGCC TCTCCTGATT TCCTAGCTAC CCCAGAGGAG 
AAGGAACAAA AGTCTCACTG CATCTGTATG AACGAGCGGC ATACCATGTC CTGGGCGGTG 
ATCCCCAAGT CATTAGGAAA TGTGAATTTC ACAGTGAGTG CAGAGGCACT GGACTCTAAG 
GAGCTGTGTA GGAATGAGGT GCCAGTGGTT CCTGAACGTG GAAAGAAAGA CACGATCATC 
AAGTCCCTGC TGGTTGAACC TGAAGGTCTA GAGAATGAAG TGACATTCAA CAGTTTGCTT 
TGTCCAACAG GTGCTGAGCT ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239624.1
CDS	125..2911
Translation	MGKRWLPSLALLPLPPPLLLLLLLLLPTNASAPQKPIYMVMVPSLLHAGTPEKGCLLFNHLNETVTVKVSMESVRGNQSLFTDLVVDKDLFHCASFIVPQSSSNEVMFLTVQVKGPTHEFRRRSTVLIKTKESLVFAQTDKPIYKPGQMVRFRVVSLDENFHPLNELIPLLYIQDSKKNRIAQWQNFRLEGGLKQLSFPLSSEPTQGSYKVVIRTESGRTVEHPFSVKEFVLPKFEVKVAVPETITILEEEMNVSVCGIYTYGKPVPGHVTVNICRKYSNPSSCFGEESLAFCEKFSQQLDGRGCFSQLVKTKSFQLKRQEYEMQLDVNAKIQEEGTGVEETGKGLTKITRTITKLSFVNVDTHFRQGIPFVGQVLLVDGRGTPIPYEMIFIGADEANQNINTTTDKNGLARFSINTDDIMGTSLTVRAKYKDSNVCYGFRWLTEENVEAWHTANAVFSPSRSFVHLESLPYKLRCEQTLAVQAHYILNDEAVLERKELVFYYLMMAKGGIVRAGTHVLPVTQGHKKGHFSILISMETDLAPVARLVLYTILPNGEVVGDTVKYEIEKCLANKVDLVFHPNIGLPATRAFLSVMASPQSLCGLRAVDQSVLLTKPEAELSASLVYDLLPVKDLTGFPKGVNQQEEDTNGCLKQNDTYINGILYSPVQNTNEEDMYGFLKDMGLKVFTNLNIRKPKVCERLGVNKIPAAYHLVSQGHMDAFLESSESPTETTRSYFPETWIWDLVIVDSTGVAEMEVTVPDTITEWKAGAFCLSNDTGLGLSPVIDFQAFQPFFVDLTMPYSVIRGEAFTLKATVLNYLQTCIRVGVQLEASPDFLATPEEKEQKSHCICMNERHTMSWAVIPKSLGNVNFTVSAEALDSKELCRNEVPVVPERGKKDTIIKSLLVEPEGLENEVTFNSLLCPTGAELF

Target ORF information:

RefSeq Version	XM_011241322.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus alpha-2-macroglobulin (A2m), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241322.2

ORF Insert Sequence:

ATGGGGAAGC GCTGGCTCCC AAGCCTGGCC CTGCTGCCGC TGCCGCCACC GCTGCTGCTG 
CTGCTGTTGC TGCTGCTGCC CACAAATGCC TCAGCACCAC AGAAACCAAT CTACATGGTG 
ATGGTTCCCT CCCTGCTCCA CGCTGGCACC CCTGAGAAGG GCTGCCTCCT GTTCAACCAC 
CTAAACGAGA CAGTAACAGT GAAAGTATCC ATGGAGTCTG TCCGTGGGAA CCAAAGCCTC 
TTCACTGACC TTGTTGTTGA CAAGGACTTA TTCCACTGTG CCTCCTTCAT CGTCCCACAG 
TCTTCATCCA ATGAGGTGAT GTTTCTCACT GTCCAAGTAA AAGGACCAAC TCATGAGTTC 
AGGAGGAGGA GCACGGTGCT GATCAAGACT AAAGAGAGCC TGGTCTTTGC TCAGACTGAC 
AAGCCCATCT ACAAACCAGG ACAGATGGTG AGATTTCGTG TTGTCTCATT GGACGAAAAT 
TTCCACCCCC TTAATGAATT GATTCCTCTA CTGTACATTC AGGATTCAAA AAAAAATCGC 
ATTGCACAGT GGCAGAATTT CCGCTTAGAG GGTGGCCTCA AACAGCTGTC CTTCCCCCTC 
TCCTCAGAGC CCACTCAGGG CTCCTACAAG GTGGTGATAC GTACAGAATC AGGCAGGACC 
GTCGAGCACC CCTTCTCTGT GAAGGAATTT GTGCTTCCCA AGTTTGAAGT CAAAGTTGCA 
GTACCAGAGA CAATCACCAT CCTGGAGGAA GAGATGAATG TGTCCGTGTG TGGCATATAC 
ACCTATGGGA AGCCTGTTCC AGGACACGTG ACTGTGAACA TTTGCAGAAA GTACAGTAAT 
CCTTCTAGCT GCTTTGGTGA AGAATCGCTG GCTTTCTGTG AGAAATTCAG TCAACAGCTA 
GATGGCCGTG GCTGCTTCTC ACAGCTAGTG AAAACCAAGT CTTTCCAGCT AAAGAGGCAA 
GAGTATGAGA TGCAGCTTGA TGTGAATGCC AAGATCCAAG AAGAAGGAAC AGGTGTGGAA 
GAAACCGGTA AAGGGCTCAC TAAGATCACA AGAACTATAA CAAAACTATC ATTTGTGAAC 
GTGGATACAC ATTTCAGACA AGGAATTCCT TTCGTTGGGC AGGTGCTCCT GGTGGATGGG 
AGAGGCACCC CTATTCCATA TGAAATGATC TTCATTGGAG CTGATGAAGC AAACCAGAAC 
ATAAATACTA CCACTGATAA GAATGGCCTG GCACGGTTCT CCATCAACAC TGATGACATC 
ATGGGCACGT CCCTAACTGT CAGGGCCAAA TACAAAGATA GCAATGTCTG CTATGGATTT 
AGATGGTTGA CAGAAGAGAA CGTAGAGGCT TGGCACACTG CCAACGCTGT CTTCTCACCG 
AGCAGAAGCT TCGTGCACCT GGAATCCCTG CCCTATAAAC TGCGCTGTGA GCAAACCCTG 
GCGGTCCAGG CTCATTATAT TCTAAATGAC GAGGCTGTGC TGGAGCGGAA GGAGTTGGTC 
TTCTATTATC TGATGATGGC AAAGGGAGGC ATTGTTCGGG CAGGGACTCA CGTTCTGCCT 
GTGACGCAGG GACACAAGAA AGGCCATTTC TCCATCCTCA TCTCGATGGA GACAGACCTG 
GCTCCTGTAG CTCGACTGGT CCTTTATACC ATTCTGCCCA ATGGAGAAGT GGTTGGAGAT 
ACTGTTAAAT ATGAGATTGA AAAGTGCCTG GCCAACAAGG TGGATTTGGT CTTCCACCCA 
AATATCGGTC TTCCGGCCAC ACGTGCCTTC CTCAGTGTCA TGGCTTCTCC TCAGTCTCTC 
TGTGGCCTGC GAGCTGTGGA CCAAAGCGTA CTGCTCACAA AGCCTGAGGC CGAACTCTCT 
GCATCCCTGG TTTATGATCT GCTACCAGTG AAAGACCTCA CTGGCTTCCC TAAGGGTGTG 
AATCAACAGG AAGAAGACAC TAATGGCTGC CTTAAGCAAA ATGACACTTA CATTAATGGA 
ATCCTGTACT CCCCAGTACA GAATACAAAT GAAGAGGACA TGTATGGCTT CCTAAAGGAT 
ATGGGCTTAA AGGTATTCAC CAACTTGAAC ATCCGTAAAC CCAAAGTCTG TGAACGCCTT 
GGAGTCAATA AAATACCAGC TGCATACCAC CTTGTAAGCC AAGGCCACAT GGATGCTTTT 
CTAGAGTCTT CAGAGTCTCC CACAGAGACT ACACGAAGCT ACTTCCCTGA GACGTGGATC 
TGGGACTTGG TGATCGTGGA CTCAACAGGA GTGGCTGAAA TGGAAGTGAC AGTCCCTGAC 
ACCATCACTG AATGGAAGGC TGGGGCCTTC TGCCTGTCCA ATGACACTGG GTTGGGCCTC 
TCTCCTGTGA TCGATTTCCA AGCCTTCCAG CCCTTCTTCG TGGATCTCAC AATGCCCTAC 
TCCGTGATCC GTGGAGAGGC CTTCACGCTC AAGGCCACTG TGCTGAACTA CCTCCAGACA 
TGCATCCGGG TTGGTGTACA GCTGGAGGCC TCTCCTGATT TCCTAGCTAC CCCAGAGGAG 
AAGGAACAAA AGTCTCACTG CATCTGTATG AACGAGCGGC ATACCATGTC CTGGGCGGTG 
ATCCCCAAGT CATTAGGAAA TGTGAATTTC ACAGTGAGTG CAGAGGCACT GGACTCTAAG 
GAGCTGTGTA GGAATGAGGT GCCAGTGGTT CCTGAACGTG GAAAGAAAGA CACGATCATC 
AAGTCCCTGC TGGTTGAACC TGAAGGTCTA GAGAATGAAG TGACATTCAA CAGTTTGCTT 
TGTCCAACAG GTGCTGAGCT ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2m ( NM_175628.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_783327.2 Mus musculus alpha-2-macroglobulin (A2m), mRNA.

Price & Availability↑

CloneID	OMu05590
Clone ID Related Accession (Same CDS sequence)	NM_175628.3
Accession Version	NM_175628.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	alpha-2-macroglobulin-P precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY785372.1, BC072642.1, CN701262.1 and AI850558.1. On May 23, 2007 this sequence version replaced NM_175628.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY185125.1, BC072642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGC GCTGGCTCCC AAGCCTGGCC CTGCTGCCGC TGCCGCCACC GCTGCTGCTG 
CTGCTGTTGC TGCTGCTGCC CACAAATGCC TCAGCACCAC AGAAACCAAT CTACATGGTG 
ATGGTTCCCT CCCTGCTCCA CGCTGGCACC CCTGAGAAGG GCTGCCTCCT GTTCAACCAC 
CTAAACGAGA CAGTAACAGT GAAAGTATCC ATGGAGTCTG TCCGTGGGAA CCAAAGCCTC 
TTCACTGACC TTGTTGTTGA CAAGGACTTA TTCCACTGTG CCTCCTTCAT CGTCCCACAG 
TCTTCATCCA ATGAGGTGAT GTTTCTCACT GTCCAAGTAA AAGGACCAAC TCATGAGTTC 
AGGAGGAGGA GCACGGTGCT GATCAAGACT AAAGAGAGCC TGGTCTTTGC TCAGACTGAC 
AAGCCCATCT ACAAACCAGG ACAGATGGTG AGATTTCGTG TTGTCTCATT GGACGAAAAT 
TTCCACCCCC TTAATGAATT GATTCCTCTA CTGTACATTC AGGATTCAAA AAAAAATCGC 
ATTGCACAGT GGCAGAATTT CCGCTTAGAG GGTGGCCTCA AACAGCTGTC CTTCCCCCTC 
TCCTCAGAGC CCACTCAGGG CTCCTACAAG GTGGTGATAC GTACAGAATC AGGCAGGACC 
GTCGAGCACC CCTTCTCTGT GAAGGAATTT GTGCTTCCCA AGTTTGAAGT CAAAGTTGCA 
GTACCAGAGA CAATCACCAT CCTGGAGGAA GAGATGAATG TGTCCGTGTG TGGCATATAC 
ACCTATGGGA AGCCTGTTCC AGGACACGTG ACTGTGAACA TTTGCAGAAA GTACAGTAAT 
CCTTCTAGCT GCTTTGGTGA AGAATCGCTG GCTTTCTGTG AGAAATTCAG TCAACAGCTA 
GATGGCCGTG GCTGCTTCTC ACAGCTAGTG AAAACCAAGT CTTTCCAGCT AAAGAGGCAA 
GAGTATGAGA TGCAGCTTGA TGTGAATGCC AAGATCCAAG AAGAAGGAAC AGGTGTGGAA 
GAAACCGGTA AAGGGCTCAC TAAGATCACA AGAACTATAA CAAAACTATC ATTTGTGAAC 
GTGGATACAC ATTTCAGACA AGGAATTCCT TTCGTTGGGC AGGTGCTCCT GGTGGATGGG 
AGAGGCACCC CTATTCCATA TGAAATGATC TTCATTGGAG CTGATGAAGC AAACCAGAAC 
ATAAATACTA CCACTGATAA GAATGGCCTG GCACGGTTCT CCATCAACAC TGATGACATC 
ATGGGCACGT CCCTAACTGT CAGGGCCAAA TACAAAGATA GCAATGTCTG CTATGGATTT 
AGATGGTTGA CAGAAGAGAA CGTAGAGGCT TGGCACACTG CCAACGCTGT CTTCTCACCG 
AGCAGAAGCT TCGTGCACCT GGAATCCCTG CCCTATAAAC TGCGCTGTGA GCAAACCCTG 
GCGGTCCAGG CTCATTATAT TCTAAATGAC GAGGCTGTGC TGGAGCGGAA GGAGTTGGTC 
TTCTATTATC TGATGATGGC AAAGGGAGGC ATTGTTCGGG CAGGGACTCA CGTTCTGCCT 
GTGACGCAGG GACACAAGAA AGGCCATTTC TCCATCCTCA TCTCGATGGA GACAGACCTG 
GCTCCTGTAG CTCGACTGGT CCTTTATACC ATTCTGCCCA ATGGAGAAGT GGTTGGAGAT 
ACTGTTAAAT ATGAGATTGA AAAGTGCCTG GCCAACAAGG TGGATTTGGT CTTCCACCCA 
AATATCGGTC TTCCGGCCAC ACGTGCCTTC CTCAGTGTCA TGGCTTCTCC TCAGTCTCTC 
TGTGGCCTGC GAGCTGTGGA CCAAAGCGTA CTGCTCACAA AGCCTGAGGC CGAACTCTCT 
GCATCCCTGG TTTATGATCT GCTACCAGTG AAAGACCTCA CTGGCTTCCC TAAGGGTGTG 
AATCAACAGG AAGAAGACAC TAATGGCTGC CTTAAGCAAA ATGACACTTA CATTAATGGA 
ATCCTGTACT CCCCAGTACA GAATACAAAT GAAGAGGACA TGTATGGCTT CCTAAAGGAT 
ATGGGCTTAA AGGTATTCAC CAACTTGAAC ATCCGTAAAC CCAAAGTCTG TGAACGCCTT 
GGAGTCAATA AAATACCAGC TGCATACCAC CTTGTAAGCC AAGGCCACAT GGATGCTTTT 
CTAGAGTCTT CAGAGTCTCC CACAGAGACT ACACGAAGCT ACTTCCCTGA GACGTGGATC 
TGGGACTTGG TGATCGTGGA CTCAACAGGA GTGGCTGAAA TGGAAGTGAC AGTCCCTGAC 
ACCATCACTG AATGGAAGGC TGGGGCCTTC TGCCTGTCCA ATGACACTGG GTTGGGCCTC 
TCTCCTGTGA TCGATTTCCA AGCCTTCCAG CCCTTCTTCG TGGATCTCAC AATGCCCTAC 
TCCGTGATCC GTGGAGAGGC CTTCACGCTC AAGGCCACTG TGCTGAACTA CCTCCAGACA 
TGCATCCGGG TTGGTGTACA GCTGGAGGCC TCTCCTGATT TCCTAGCTAC CCCAGAGGAG 
AAGGAACAAA AGTCTCACTG CATCTGTATG AACGAGCGGC ATACCATGTC CTGGGCGGTG 
ATCCCCAAGT CATTAGGAAA TGTGAATTTC ACAGTGAGTG CAGAGGCACT GGACTCTAAG 
GAGCTGTGTA GGAATGAGGT GCCAGTGGTT CCTGAACGTG GAAAGAAAGA CACGATCATC 
AAGTCCCTGC TGGTTGAACC TGAAGGTCTA GAGAATGAAG TGACATTCAA CAGTTTGCTT 
TGTCCAACAG GTGCTGAGGT ATCGGAACAG ATATCTCTGA AACTGCCATC AGATGTGGTA 
GAGGAATCTG CCCGAGCTTC TGTCACAGTT TTGGGAGATA TATTGGGTTC TGCTATGCAG 
AACACACAGG ATCTCCTTAA GATGCCCTAT GGCTGTGGAG AACAGAACAT GGTTCTGTTT 
GCTCCTAATA TCTATGTCCT GGACTATCTG AATGAAACAG AGCAGCTGAC ACAGGAGATC 
AAGACCAAGG CCATTACCTA TCTCAATACG GGTTACCAAA GACAATTAAA CTACAAGCAC 
CGGGATGGCT CCTACAGTAC TTTTGGGGAT AAACCTGGTA GGAGTCATGC CAATACCTGG 
CTCACAGCCT TTGTACTGAA GAGTTTTGCT CAGGCTCGAA GATATATCTT CATCGATGAA 
TCACACATCA CCCAAGCCCT CACCTGGCTC TCCCAGCAGC AGAAGGACAA TGGCTGCTTC 
AGGAGCTCCG GGTCACTGCT CAACAATGCC ATGAAGGGAG GAGTAGAAGA TGAAGTCACT 
TTGTCTGCCT ACATCACCAT TGCTCTCCTG GAGATGTCTC TTCCTGTCAC TCATCCTGTT 
GTCCGAAATG CCCTCTTTTG CCTGGACACA GCCTGGAAGT CAGCGAGGAG AGGAGCCAGC 
GGCAACCATG TCTACACTAA GGCACTGTTG GCCTATGCAT TTGCCCTTGC TGGTAACCAG 
GACACGAAGA AGGAGATACT GAAATCACTC GATGAGGAGG CGGTAAAAGA AGACAATTCT 
GTCCACTGGA CCAGAGCTCA GAAACCCAGA GTGCCAGCAG ATCTCTGGTA CCAACCCCAG 
GCTCCCTCGG CTGAGGTAGA GATGACCGCT TATGTGCTCC TGGCTTATCT TACCACTGAG 
CTGGTTCCAA CCCGAGAGGA CCTGACTGCT GCAATGCTCA TTGTGAAGTG GCTCACAAAG 
CAGCAGAATT CCCACGGTGG CTTCTCCTCC ACCCAGGACA CGGTAGTGGC TCTCCATGCT 
TTGTCCAAAT ACGGAGCAGC TACTTTCACA AGAGCGAAGA AAGCTGCACA TGTGACCATC 
CAGTCTTCTG GCGCATTTTA TACAAAATTC CAAGTGAACA ACGACAACCA GTTATTATTA 
CAGAGAGTCA CATTGCCAAC TGTGCCTGGG GATTACACCG CAAAGGTAGC TGGAGAAGGG 
TGTGTCTACC TCCAGACATC CTTGAAATAT AGTGTTCTCC CGAGGGAGAA GGAGTTTCCA 
TTTGCTTTGG TGGTGCAGAC TCTGCCTGGG ACTTGTGAGG ATCTCAAAGC TCACACCACC 
TTCCAGATCT CACTCAATAT CAGTTACATT GGAAGCCGTT CTGACTCCAA CATGGCAATT 
GCTGATGTGA AGATGGTGTC TGGCTTCATC CCCTTGAAAC CAACAGTGAA AATGCTTGAA 
AGATCTGTGC ATGTGAGCCG GACGGAAGTC AGCAATAACC ATGTCTTGAT TTACTTGGAT 
AAGGTGTCAA ATCAGATGCT GACCTTGTTC TTCATGGTGC AGCAAGATAT TCCAGTGAGA 
GACCTGAAGC CAGCCATAGT GAAAGTCTAT GATTACTACG AGAAAGATGA GTTTGCAGTT 
GCAAAATACA GTGCTCCCTG CAGTGCAGGT TATGGAAATG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_783327.2
CDS	117..4541
Translation	MGKRWLPSLALLPLPPPLLLLLLLLLPTNASAPQKPIYMVMVPSLLHAGTPEKGCLLFNHLNETVTVKVSMESVRGNQSLFTDLVVDKDLFHCASFIVPQSSSNEVMFLTVQVKGPTHEFRRRSTVLIKTKESLVFAQTDKPIYKPGQMVRFRVVSLDENFHPLNELIPLLYIQDSKKNRIAQWQNFRLEGGLKQLSFPLSSEPTQGSYKVVIRTESGRTVEHPFSVKEFVLPKFEVKVAVPETITILEEEMNVSVCGIYTYGKPVPGHVTVNICRKYSNPSSCFGEESLAFCEKFSQQLDGRGCFSQLVKTKSFQLKRQEYEMQLDVNAKIQEEGTGVEETGKGLTKITRTITKLSFVNVDTHFRQGIPFVGQVLLVDGRGTPIPYEMIFIGADEANQNINTTTDKNGLARFSINTDDIMGTSLTVRAKYKDSNVCYGFRWLTEENVEAWHTANAVFSPSRSFVHLESLPYKLRCEQTLAVQAHYILNDEAVLERKELVFYYLMMAKGGIVRAGTHVLPVTQGHKKGHFSILISMETDLAPVARLVLYTILPNGEVVGDTVKYEIEKCLANKVDLVFHPNIGLPATRAFLSVMASPQSLCGLRAVDQSVLLTKPEAELSASLVYDLLPVKDLTGFPKGVNQQEEDTNGCLKQNDTYINGILYSPVQNTNEEDMYGFLKDMGLKVFTNLNIRKPKVCERLGVNKIPAAYHLVSQGHMDAFLESSESPTETTRSYFPETWIWDLVIVDSTGVAEMEVTVPDTITEWKAGAFCLSNDTGLGLSPVIDFQAFQPFFVDLTMPYSVIRGEAFTLKATVLNYLQTCIRVGVQLEASPDFLATPEEKEQKSHCICMNERHTMSWAVIPKSLGNVNFTVSAEALDSKELCRNEVPVVPERGKKDTIIKSLLVEPEGLENEVTFNSLLCPTGAEVSEQISLKLPSDVVEESARASVTVLGDILGSAMQNTQDLLKMPYGCGEQNMVLFAPNIYVLDYLNETEQLTQEIKTKAITYLNTGYQRQLNYKHRDGSYSTFGDKPGRSHANTWLTAFVLKSFAQARRYIFIDESHITQALTWLSQQQKDNGCFRSSGSLLNNAMKGGVEDEVTLSAYITIALLEMSLPVTHPVVRNALFCLDTAWKSARRGASGNHVYTKALLAYAFALAGNQDTKKEILKSLDEEAVKEDNSVHWTRAQKPRVPADLWYQPQAPSAEVEMTAYVLLAYLTTELVPTREDLTAAMLIVKWLTKQQNSHGGFSSTQDTVVALHALSKYGAATFTRAKKAAHVTIQSSGAFYTKFQVNNDNQLLLQRVTLPTVPGDYTAKVAGEGCVYLQTSLKYSVLPREKEFPFALVVQTLPGTCEDLKAHTTFQISLNISYIGSRSDSNMAIADVKMVSGFIPLKPTVKMLERSVHVSRTEVSNNHVLIYLDKVSNQMLTLFFMVQQDIPVRDLKPAIVKVYDYYEKDEFAVAKYSAPCSAGYGNA

Target ORF information:

RefSeq Version	NM_175628.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus alpha-2-macroglobulin (A2m), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175628.3

ORF Insert Sequence:

ATGGGGAAGC GCTGGCTCCC AAGCCTGGCC CTGCTGCCGC TGCCGCCACC GCTGCTGCTG 
CTGCTGTTGC TGCTGCTGCC CACAAATGCC TCAGCACCAC AGAAACCAAT CTACATGGTG 
ATGGTTCCCT CCCTGCTCCA CGCTGGCACC CCTGAGAAGG GCTGCCTCCT GTTCAACCAC 
CTAAACGAGA CAGTAACAGT GAAAGTATCC ATGGAGTCTG TCCGTGGGAA CCAAAGCCTC 
TTCACTGACC TTGTTGTTGA CAAGGACTTA TTCCACTGTG CCTCCTTCAT CGTCCCACAG 
TCTTCATCCA ATGAGGTGAT GTTTCTCACT GTCCAAGTAA AAGGACCAAC TCATGAGTTC 
AGGAGGAGGA GCACGGTGCT GATCAAGACT AAAGAGAGCC TGGTCTTTGC TCAGACTGAC 
AAGCCCATCT ACAAACCAGG ACAGATGGTG AGATTTCGTG TTGTCTCATT GGACGAAAAT 
TTCCACCCCC TTAATGAATT GATTCCTCTA CTGTACATTC AGGATTCAAA AAAAAATCGC 
ATTGCACAGT GGCAGAATTT CCGCTTAGAG GGTGGCCTCA AACAGCTGTC CTTCCCCCTC 
TCCTCAGAGC CCACTCAGGG CTCCTACAAG GTGGTGATAC GTACAGAATC AGGCAGGACC 
GTCGAGCACC CCTTCTCTGT GAAGGAATTT GTGCTTCCCA AGTTTGAAGT CAAAGTTGCA 
GTACCAGAGA CAATCACCAT CCTGGAGGAA GAGATGAATG TGTCCGTGTG TGGCATATAC 
ACCTATGGGA AGCCTGTTCC AGGACACGTG ACTGTGAACA TTTGCAGAAA GTACAGTAAT 
CCTTCTAGCT GCTTTGGTGA AGAATCGCTG GCTTTCTGTG AGAAATTCAG TCAACAGCTA 
GATGGCCGTG GCTGCTTCTC ACAGCTAGTG AAAACCAAGT CTTTCCAGCT AAAGAGGCAA 
GAGTATGAGA TGCAGCTTGA TGTGAATGCC AAGATCCAAG AAGAAGGAAC AGGTGTGGAA 
GAAACCGGTA AAGGGCTCAC TAAGATCACA AGAACTATAA CAAAACTATC ATTTGTGAAC 
GTGGATACAC ATTTCAGACA AGGAATTCCT TTCGTTGGGC AGGTGCTCCT GGTGGATGGG 
AGAGGCACCC CTATTCCATA TGAAATGATC TTCATTGGAG CTGATGAAGC AAACCAGAAC 
ATAAATACTA CCACTGATAA GAATGGCCTG GCACGGTTCT CCATCAACAC TGATGACATC 
ATGGGCACGT CCCTAACTGT CAGGGCCAAA TACAAAGATA GCAATGTCTG CTATGGATTT 
AGATGGTTGA CAGAAGAGAA CGTAGAGGCT TGGCACACTG CCAACGCTGT CTTCTCACCG 
AGCAGAAGCT TCGTGCACCT GGAATCCCTG CCCTATAAAC TGCGCTGTGA GCAAACCCTG 
GCGGTCCAGG CTCATTATAT TCTAAATGAC GAGGCTGTGC TGGAGCGGAA GGAGTTGGTC 
TTCTATTATC TGATGATGGC AAAGGGAGGC ATTGTTCGGG CAGGGACTCA CGTTCTGCCT 
GTGACGCAGG GACACAAGAA AGGCCATTTC TCCATCCTCA TCTCGATGGA GACAGACCTG 
GCTCCTGTAG CTCGACTGGT CCTTTATACC ATTCTGCCCA ATGGAGAAGT GGTTGGAGAT 
ACTGTTAAAT ATGAGATTGA AAAGTGCCTG GCCAACAAGG TGGATTTGGT CTTCCACCCA 
AATATCGGTC TTCCGGCCAC ACGTGCCTTC CTCAGTGTCA TGGCTTCTCC TCAGTCTCTC 
TGTGGCCTGC GAGCTGTGGA CCAAAGCGTA CTGCTCACAA AGCCTGAGGC CGAACTCTCT 
GCATCCCTGG TTTATGATCT GCTACCAGTG AAAGACCTCA CTGGCTTCCC TAAGGGTGTG 
AATCAACAGG AAGAAGACAC TAATGGCTGC CTTAAGCAAA ATGACACTTA CATTAATGGA 
ATCCTGTACT CCCCAGTACA GAATACAAAT GAAGAGGACA TGTATGGCTT CCTAAAGGAT 
ATGGGCTTAA AGGTATTCAC CAACTTGAAC ATCCGTAAAC CCAAAGTCTG TGAACGCCTT 
GGAGTCAATA AAATACCAGC TGCATACCAC CTTGTAAGCC AAGGCCACAT GGATGCTTTT 
CTAGAGTCTT CAGAGTCTCC CACAGAGACT ACACGAAGCT ACTTCCCTGA GACGTGGATC 
TGGGACTTGG TGATCGTGGA CTCAACAGGA GTGGCTGAAA TGGAAGTGAC AGTCCCTGAC 
ACCATCACTG AATGGAAGGC TGGGGCCTTC TGCCTGTCCA ATGACACTGG GTTGGGCCTC 
TCTCCTGTGA TCGATTTCCA AGCCTTCCAG CCCTTCTTCG TGGATCTCAC AATGCCCTAC 
TCCGTGATCC GTGGAGAGGC CTTCACGCTC AAGGCCACTG TGCTGAACTA CCTCCAGACA 
TGCATCCGGG TTGGTGTACA GCTGGAGGCC TCTCCTGATT TCCTAGCTAC CCCAGAGGAG 
AAGGAACAAA AGTCTCACTG CATCTGTATG AACGAGCGGC ATACCATGTC CTGGGCGGTG 
ATCCCCAAGT CATTAGGAAA TGTGAATTTC ACAGTGAGTG CAGAGGCACT GGACTCTAAG 
GAGCTGTGTA GGAATGAGGT GCCAGTGGTT CCTGAACGTG GAAAGAAAGA CACGATCATC 
AAGTCCCTGC TGGTTGAACC TGAAGGTCTA GAGAATGAAG TGACATTCAA CAGTTTGCTT 
TGTCCAACAG GTGCTGAGGT ATCGGAACAG ATATCTCTGA AACTGCCATC AGATGTGGTA 
GAGGAATCTG CCCGAGCTTC TGTCACAGTT TTGGGAGATA TATTGGGTTC TGCTATGCAG 
AACACACAGG ATCTCCTTAA GATGCCCTAT GGCTGTGGAG AACAGAACAT GGTTCTGTTT 
GCTCCTAATA TCTATGTCCT GGACTATCTG AATGAAACAG AGCAGCTGAC ACAGGAGATC 
AAGACCAAGG CCATTACCTA TCTCAATACG GGTTACCAAA GACAATTAAA CTACAAGCAC 
CGGGATGGCT CCTACAGTAC TTTTGGGGAT AAACCTGGTA GGAGTCATGC CAATACCTGG 
CTCACAGCCT TTGTACTGAA GAGTTTTGCT CAGGCTCGAA GATATATCTT CATCGATGAA 
TCACACATCA CCCAAGCCCT CACCTGGCTC TCCCAGCAGC AGAAGGACAA TGGCTGCTTC 
AGGAGCTCCG GGTCACTGCT CAACAATGCC ATGAAGGGAG GAGTAGAAGA TGAAGTCACT 
TTGTCTGCCT ACATCACCAT TGCTCTCCTG GAGATGTCTC TTCCTGTCAC TCATCCTGTT 
GTCCGAAATG CCCTCTTTTG CCTGGACACA GCCTGGAAGT CAGCGAGGAG AGGAGCCAGC 
GGCAACCATG TCTACACTAA GGCACTGTTG GCCTATGCAT TTGCCCTTGC TGGTAACCAG 
GACACGAAGA AGGAGATACT GAAATCACTC GATGAGGAGG CGGTAAAAGA AGACAATTCT 
GTCCACTGGA CCAGAGCTCA GAAACCCAGA GTGCCAGCAG ATCTCTGGTA CCAACCCCAG 
GCTCCCTCGG CTGAGGTAGA GATGACCGCT TATGTGCTCC TGGCTTATCT TACCACTGAG 
CTGGTTCCAA CCCGAGAGGA CCTGACTGCT GCAATGCTCA TTGTGAAGTG GCTCACAAAG 
CAGCAGAATT CCCACGGTGG CTTCTCCTCC ACCCAGGACA CGGTAGTGGC TCTCCATGCT 
TTGTCCAAAT ACGGAGCAGC TACTTTCACA AGAGCGAAGA AAGCTGCACA TGTGACCATC 
CAGTCTTCTG GCGCATTTTA TACAAAATTC CAAGTGAACA ACGACAACCA GTTATTATTA 
CAGAGAGTCA CATTGCCAAC TGTGCCTGGG GATTACACCG CAAAGGTAGC TGGAGAAGGG 
TGTGTCTACC TCCAGACATC CTTGAAATAT AGTGTTCTCC CGAGGGAGAA GGAGTTTCCA 
TTTGCTTTGG TGGTGCAGAC TCTGCCTGGG ACTTGTGAGG ATCTCAAAGC TCACACCACC 
TTCCAGATCT CACTCAATAT CAGTTACATT GGAAGCCGTT CTGACTCCAA CATGGCAATT 
GCTGATGTGA AGATGGTGTC TGGCTTCATC CCCTTGAAAC CAACAGTGAA AATGCTTGAA 
AGATCTGTGC ATGTGAGCCG GACGGAAGTC AGCAATAACC ATGTCTTGAT TTACTTGGAT 
AAGGTGTCAA ATCAGATGCT GACCTTGTTC TTCATGGTGC AGCAAGATAT TCCAGTGAGA 
GACCTGAAGC CAGCCATAGT GAAAGTCTAT GATTACTACG AGAAAGATGA GTTTGCAGTT 
GCAAAATACA GTGCTCCCTG CAGTGCAGGT TATGGAAATG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.
Nucleic acid therapeutics26(4)223-35(2016 08)
Shemesh CS,Yu RZ,Gaus HJ,Seth PP,Swayze EE,Bennett FC,Geary RS,Henry SP,Wang Y

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.
PloS one7(7)e40735(2012)
Son EJ,Wu L,Yoon H,Kim S,Choi JY,Bok J

Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells.
Genomics22(3)519-29(1994 Aug)
Umans L,Serneels L,Hilliker C,Stas L,Overbergh L,De Strooper B,Van Leuven F,Van den Berghe H

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

A2m cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM