Mob1a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mob1a
Entrez Gene ID	232157
Full Name	MOB kinase activator 1A
Synonyms	4022402H07Rik,MOB1,MOB4B,Mobk1b,Mobkl1b
General protein information	Preferred Names MOB kinase activator 1A Names MOB kinase activator 1A MOB1, Mps One Binder kinase activator-like 1B mob1 homolog 1B mps one binder kinase activator-like 1B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 C3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006505969.3	XP_006506032.1	MOB kinase activator 1A isoform X1
XM_006505969.4	XP_006506032.1	MOB kinase activator 1A isoform X1
NM_145571.2	NP_663546.1	MOB kinase activator 1A

Pathways from BioSystems

Homologies

Homo sapiens (human)	MOB1A	NP_060691.2
Pan troglodytes (chimpanzee)	MOBKL1B	XP_515735.1
Bos taurus (cattle)	MOB1A	NP_001069806.1
Mus musculus (house mouse)	Mob1a	NP_663546.1
Rattus norvegicus (Norway rat)	Mob1a	NP_001029063.1
Eremothecium gossypii	AGOS_ADL236W	NP_983860.1
Schizosaccharomyces pombe (fission yeast)	mob1	NP_595191.1
Gallus gallus (chicken)	LOC429657	XP_427212.3
Saccharomyces cerevisiae (baker's yeast)	MOB1	NP_012160.2
Oryza sativa (rice)	Os10g0396300	NP_001064531.2
Neurospora crassa	NCU01605	XP_956516.2
Xenopus tropicalis (tropical clawed frog)	mob1a	NP_001017026.1
Danio rerio (zebrafish)	mob1a	NP_956208.1
Magnaporthe oryzae (rice blast fungus)	MGG_03151	XP_003716843.1
Macaca mulatta (Rhesus monkey)	MOBKL1B	XP_001110775.1
Danio rerio (zebrafish)	LOC100331697	XP_002662246.1
Kluyveromyces lactis	KLLA0F03795g	XP_455252.1
Canis lupus familiaris (dog)	MOB1A	XP_852858.1

Gene Ontology
Bibliography

Related articles in PubMed

MOB1 regulates thymocyte egress and T-cell survival in mice in a YAP1-independent manner.
Kato W, Nishio M, To Y, Togashi H, Mak TW, Takada H, Ohga S, Maehama T, Suzuki A
Genes to cells : devoted to molecular & cellular mechanisms24(7)485-495(2019 Jul)

Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling.
Bae JS, Jeon Y, Kim SM, Jang JY, Park MK, Kim IH, Hwang DS, Lim DS, Lee H
Cell death & disease9(11)1083(2018 10)

Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H
Proceedings of the National Academy of Sciences of the United States of America115(17)E4101-E4110(2018 04)

Loss of
Goto H, Nishio M, To Y, Oishi T, Miyachi Y, Maehama T, Nishina H, Akiyama H, Mak TW, Makii Y, Saito T, Yasoda A, Tsumaki N, Suzuki A
Development (Cambridge, England)145(6)(2018 03)

YAP determines the cell fate of injured mouse hepatocytes in vivo.
Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H
Nature communications816017(2017 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mob1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mob1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu37166	XM_006505969.4 Latest version!	Mus musculus MOB kinase activator 1A (Mob1a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu11805	NM_145571.2 Latest version!	Mus musculus MOB kinase activator 1A (Mob1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OMu37166	XM_006505969.3	Mus musculus MOB kinase activator 1A (Mob1a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mob1a ( XM_006505969.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506032.1 Mus musculus MOB kinase activator 1A (Mob1a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37166
Clone ID Related Accession (Same CDS sequence)	XM_006505969.3 , XM_006505969.4
Accession Version	XM_006505969.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	MOB kinase activator 1A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006505969.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTTCC TCTTCAGCCG CTCTTCGAAA ACATTCAAAC CAAAGAAGAA TATCCCTGAA 
GGGTCCCATC AGTATGAGCT CTTGAAGCAT GCAGAGGCGA CTCTCGGAAG TGGCAATCTG 
AGGCAAGCTG TTATGTTGCC TGAGGGAGAG GACCTCAATG AATGGATTGC TGTTAATACT 
GTGGATTTCT TCAATCAGAT CAACATGTTG TATGGAACCA TTACAGAATT CTGCACTGAG 
GCAAGCTGCC CAGTCATGTC GGCAGGTCCC AGGTATGAAT ACCACTGGGC AGATGGCACT 
AATATTAAAA AGCCAATTAA GTGTTCTGCA CCAAAATATA TTGACTATTT GATGACTTGG 
GTTCAGGATC AGCTTGATGA CGAAACTCTT TTTCCTTCTA AGATTGGTGT CCCTTTTCCC 
AAAAACTTTA TGTCTGTGGC AAAGACTATT CTGAAGCGTC TCTTCAGGGT TTATGCCCAT 
ATCTACCACC AGCACTTTGA CTCCGTGATG CAGCTGCAGG AGGAGGCTCA CCTCAACACC 
TCCTTTAAGC ACTTTATTTT CTTTGTTCAG GAGTTTAATC TGATTGATAG GCGTGAGTTG 
GCACCACTTC AGGAATTAAT TGAGAAGCTT GGATCTAAAG ACAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506032.1
CDS	220..867
Translation	MSFLFSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR

Target ORF information:

RefSeq Version	XM_006505969.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus MOB kinase activator 1A (Mob1a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006505969.3

ORF Insert Sequence:

ATGAGCTTCC TCTTCAGCCG CTCTTCGAAA ACATTCAAAC CAAAGAAGAA TATCCCTGAA 
GGGTCCCATC AGTATGAGCT CTTGAAGCAT GCAGAGGCGA CTCTCGGAAG TGGCAATCTG 
AGGCAAGCTG TTATGTTGCC TGAGGGAGAG GACCTCAATG AATGGATTGC TGTTAATACT 
GTGGATTTCT TCAATCAGAT CAACATGTTG TATGGAACCA TTACAGAATT CTGCACTGAG 
GCAAGCTGCC CAGTCATGTC GGCAGGTCCC AGGTATGAAT ACCACTGGGC AGATGGCACT 
AATATTAAAA AGCCAATTAA GTGTTCTGCA CCAAAATATA TTGACTATTT GATGACTTGG 
GTTCAGGATC AGCTTGATGA CGAAACTCTT TTTCCTTCTA AGATTGGTGT CCCTTTTCCC 
AAAAACTTTA TGTCTGTGGC AAAGACTATT CTGAAGCGTC TCTTCAGGGT TTATGCCCAT 
ATCTACCACC AGCACTTTGA CTCCGTGATG CAGCTGCAGG AGGAGGCTCA CCTCAACACC 
TCCTTTAAGC ACTTTATTTT CTTTGTTCAG GAGTTTAATC TGATTGATAG GCGTGAGTTG 
GCACCACTTC AGGAATTAAT TGAGAAGCTT GGATCTAAAG ACAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mob1a ( XM_006505969.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506032.1 Mus musculus MOB kinase activator 1A (Mob1a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37166
Clone ID Related Accession (Same CDS sequence)	XM_006505969.3 , XM_006505969.4
Accession Version	XM_006505969.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	MOB kinase activator 1A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006505969.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTTCC TCTTCAGCCG CTCTTCGAAA ACATTCAAAC CAAAGAAGAA TATCCCTGAA 
GGGTCCCATC AGTATGAGCT CTTGAAGCAT GCAGAGGCGA CTCTCGGAAG TGGCAATCTG 
AGGCAAGCTG TTATGTTGCC TGAGGGAGAG GACCTCAATG AATGGATTGC TGTTAATACT 
GTGGATTTCT TCAATCAGAT CAACATGTTG TATGGAACCA TTACAGAATT CTGCACTGAG 
GCAAGCTGCC CAGTCATGTC GGCAGGTCCC AGGTATGAAT ACCACTGGGC AGATGGCACT 
AATATTAAAA AGCCAATTAA GTGTTCTGCA CCAAAATATA TTGACTATTT GATGACTTGG 
GTTCAGGATC AGCTTGATGA CGAAACTCTT TTTCCTTCTA AGATTGGTGT CCCTTTTCCC 
AAAAACTTTA TGTCTGTGGC AAAGACTATT CTGAAGCGTC TCTTCAGGGT TTATGCCCAT 
ATCTACCACC AGCACTTTGA CTCCGTGATG CAGCTGCAGG AGGAGGCTCA CCTCAACACC 
TCCTTTAAGC ACTTTATTTT CTTTGTTCAG GAGTTTAATC TGATTGATAG GCGTGAGTTG 
GCACCACTTC AGGAATTAAT TGAGAAGCTT GGATCTAAAG ACAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506032.1
CDS	221..868
Translation	MSFLFSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR

Target ORF information:

RefSeq Version	XM_006505969.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus MOB kinase activator 1A (Mob1a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006505969.4

ORF Insert Sequence:

ATGAGCTTCC TCTTCAGCCG CTCTTCGAAA ACATTCAAAC CAAAGAAGAA TATCCCTGAA 
GGGTCCCATC AGTATGAGCT CTTGAAGCAT GCAGAGGCGA CTCTCGGAAG TGGCAATCTG 
AGGCAAGCTG TTATGTTGCC TGAGGGAGAG GACCTCAATG AATGGATTGC TGTTAATACT 
GTGGATTTCT TCAATCAGAT CAACATGTTG TATGGAACCA TTACAGAATT CTGCACTGAG 
GCAAGCTGCC CAGTCATGTC GGCAGGTCCC AGGTATGAAT ACCACTGGGC AGATGGCACT 
AATATTAAAA AGCCAATTAA GTGTTCTGCA CCAAAATATA TTGACTATTT GATGACTTGG 
GTTCAGGATC AGCTTGATGA CGAAACTCTT TTTCCTTCTA AGATTGGTGT CCCTTTTCCC 
AAAAACTTTA TGTCTGTGGC AAAGACTATT CTGAAGCGTC TCTTCAGGGT TTATGCCCAT 
ATCTACCACC AGCACTTTGA CTCCGTGATG CAGCTGCAGG AGGAGGCTCA CCTCAACACC 
TCCTTTAAGC ACTTTATTTT CTTTGTTCAG GAGTTTAATC TGATTGATAG GCGTGAGTTG 
GCACCACTTC AGGAATTAAT TGAGAAGCTT GGATCTAAAG ACAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mob1a ( NM_145571.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_663546.1 Mus musculus MOB kinase activator 1A (Mob1a), mRNA.

Price & Availability↑

CloneID	OMu11805
Clone ID Related Accession (Same CDS sequence)	NM_145571.2
Accession Version	NM_145571.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574006400000
Organism	Mus musculus(house mouse)
Product	MOB kinase activator 1A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK172205.1. On or before Jul 25, 2007 this sequence version replaced NM_178179.1, NM_145571.1. ##Evidence-Data-START## Transcript exon combination :: AK172205.1, AK028416.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAGCTTCC TCTTCAGCAG CCGCTCTTCG AAAACATTCA AACCAAAGAA GAATATCCCT 
GAAGGGTCCC ATCAGTATGA GCTCTTGAAG CATGCAGAGG CGACTCTCGG AAGTGGCAAT 
CTGAGGCAAG CTGTTATGTT GCCTGAGGGA GAGGACCTCA ATGAATGGAT TGCTGTTAAT 
ACTGTGGATT TCTTCAATCA GATCAACATG TTGTATGGAA CCATTACAGA ATTCTGCACT 
GAGGCAAGCT GCCCAGTCAT GTCGGCAGGT CCCAGGTATG AATACCACTG GGCAGATGGC 
ACTAATATTA AAAAGCCAAT TAAGTGTTCT GCACCAAAAT ATATTGACTA TTTGATGACT 
TGGGTTCAGG ATCAGCTTGA TGACGAAACT CTTTTTCCTT CTAAGATTGG TGTCCCTTTT 
CCCAAAAACT TTATGTCTGT GGCAAAGACT ATTCTGAAGC GTCTCTTCAG GGTTTATGCC 
CATATCTACC ACCAGCACTT TGACTCCGTG ATGCAGCTGC AGGAGGAGGC TCACCTCAAC 
ACCTCCTTTA AGCACTTTAT TTTCTTTGTT CAGGAGTTTA ATCTGATTGA TAGGCGTGAG 
TTGGCACCAC TTCAGGAATT AATTGAGAAG CTTGGATCTA AAGACAGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663546.1
CDS	216..866
Translation	MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR

Target ORF information:

RefSeq Version	NM_145571.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus MOB kinase activator 1A (Mob1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145571.2

ORF Insert Sequence:

ATGAGCTTCC TCTTCAGCAG CCGCTCTTCG AAAACATTCA AACCAAAGAA GAATATCCCT 
GAAGGGTCCC ATCAGTATGA GCTCTTGAAG CATGCAGAGG CGACTCTCGG AAGTGGCAAT 
CTGAGGCAAG CTGTTATGTT GCCTGAGGGA GAGGACCTCA ATGAATGGAT TGCTGTTAAT 
ACTGTGGATT TCTTCAATCA GATCAACATG TTGTATGGAA CCATTACAGA ATTCTGCACT 
GAGGCAAGCT GCCCAGTCAT GTCGGCAGGT CCCAGGTATG AATACCACTG GGCAGATGGC 
ACTAATATTA AAAAGCCAAT TAAGTGTTCT GCACCAAAAT ATATTGACTA TTTGATGACT 
TGGGTTCAGG ATCAGCTTGA TGACGAAACT CTTTTTCCTT CTAAGATTGG TGTCCCTTTT 
CCCAAAAACT TTATGTCTGT GGCAAAGACT ATTCTGAAGC GTCTCTTCAG GGTTTATGCC 
CATATCTACC ACCAGCACTT TGACTCCGTG ATGCAGCTGC AGGAGGAGGC TCACCTCAAC 
ACCTCCTTTA AGCACTTTAT TTTCTTTGTT CAGGAGTTTA ATCTGATTGA TAGGCGTGAG 
TTGGCACCAC TTCAGGAATT AATTGAGAAG CTTGGATCTA AAGACAGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MOB1 regulates thymocyte egress and T-cell survival in mice in a YAP1-independent manner.
Genes to cells : devoted to molecular & cellular mechanisms24(7)485-495(2019 Jul)
Kato W,Nishio M,To Y,Togashi H,Mak TW,Takada H,Ohga S,Maehama T,Suzuki A

Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling.
Cell death & disease9(11)1083(2018 10)
Bae JS,Jeon Y,Kim SM,Jang JY,Park MK,Kim IH,Hwang DS,Lim DS,Lee H

Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
Proceedings of the National Academy of Sciences of the United States of America115(17)E4101-E4110(2018 04)
Zou J,Ma W,Li J,Littlejohn R,Zhou H,Kim IM,Fulton DJR,Chen W,Weintraub NL,Zhou J,Su H

Loss of
Development (Cambridge, England)145(6)(2018 03)
Goto H,Nishio M,To Y,Oishi T,Miyachi Y,Maehama T,Nishina H,Akiyama H,Mak TW,Makii Y,Saito T,Yasoda A,Tsumaki N,Suzuki A

YAP determines the cell fate of injured mouse hepatocytes in vivo.
Nature communications816017(2017 07)
Miyamura N,Hata S,Itoh T,Tanaka M,Nishio M,Itoh M,Ogawa Y,Terai S,Sakaida I,Suzuki A,Miyajima A,Nishina H

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Mob1a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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