Uba6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Uba6
Entrez Gene ID	231380
Full Name	ubiquitin-like modifier activating enzyme 6
Synonyms	4930542H01,5730469D23Rik,AU021846,AW124799,E1-L2,Ube1l2
General protein information	Preferred Names ubiquitin-like modifier activating enzyme 6 Names ubiquitin-like modifier-activating enzyme 6 ubiquitin-activating enzyme 6 ubiquitin-activating enzyme E1-like 2 ubiquitin-activating enzyme E1-like protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 E1

mRNA and Protein(s)

mRNA	Protein	Name
NM_172712.2	NP_766300.1	ubiquitin-like modifier-activating enzyme 6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	UBA6	XP_001164227.2
Mus musculus (house mouse)	Uba6	NP_766300.1
Danio rerio (zebrafish)	si:dkey-82j4.2	XP_695755.4
Rattus norvegicus (Norway rat)	Uba6	NP_001100683.1
Xenopus tropicalis (tropical clawed frog)	uba6	XP_004911132.1
Homo sapiens (human)	UBA6	NP_060697.4
Bos taurus (cattle)	UBA6	NP_001076907.1
Gallus gallus (chicken)	UBA6	XP_420609.4
Macaca mulatta (Rhesus monkey)	UBA6	XP_002804149.1
Canis lupus familiaris (dog)	UBA6	XP_532390.2

Gene Ontology
Bibliography

Related articles in PubMed

Impairment of social behavior and communication in mice lacking the Uba6-dependent ubiquitin activation system.
Lee JY, Kwak M, Lee PC
Behavioural brain research28178-85(2015 Mar)

Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.
Lee PC, Dodart JC, Aron L, Finley LW, Bronson RT, Haigis MC, Yankner BA, Harper JW
Molecular cell50(2)172-84(2013 Apr)

Identification and expression of potential regulators of the mammalian mitotic-to-meiotic transition.
Hogarth CA, Mitchell D, Evanoff R, Small C, Griswold M
Biology of reproduction84(1)34-42(2011 Jan)

E1-L2 activates both ubiquitin and FAT10.
Chiu YH, Sun Q, Chen ZJ
Molecular cell27(6)1014-23(2007 Sep)

Identification of differentially expressed genes in mouse spermatogenesis.
Pang AL, Taylor HC, Johnson W, Alexander S, Chen Y, Su YA, Li X, Ravindranath N, Dym M, Rennert OM, Chan WY
Journal of andrology24(6)899-911(2003 Nov-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Uba6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Uba6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18547	NM_172712.2 Latest version!	Mus musculus ubiquitin-like modifier activating enzyme 6 (Uba6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Uba6 ( NM_172712.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_766300.1 Mus musculus ubiquitin-like modifier activating enzyme 6 (Uba6), mRNA.

Price & Availability↑

CloneID	OMu18547
Clone ID Related Accession (Same CDS sequence)	NM_172712.2
Accession Version	NM_172712.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3162bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559836800000
Organism	Mus musculus(house mouse)
Product	ubiquitin-like modifier-activating enzyme 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC063048.1. On Dec 20, 2003 this sequence version replaced NM_172712.1. ##Evidence-Data-START## Transcript exon combination :: BC063048.1, SRR1660813.262278.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCGGT CCGAGCCGTT GGCTGTGCTT TCCTGTGAAG AGGCGTCCTG CTCCTCCTGG 
GGAGCCTGCG GTGCAAGTAA AAATTTACCT ACCATGACAA CAGAATCTTT GGAAATCGAT 
GATGGATTAT ACAGTCGCCA GAGATATGTT CTTGGTGACA CAGCAATGCA GAAGATGGCC 
AAGTCCTGTG TCTTCTTAAG TGGTATGGGT GGTCTTGGAG TGGAAATTGC AAAGAATCTT 
GTTCTTGCAG GGATTAAGGC CCTAACAATT CATGATACAA AAAAATGCCA AGCATGGGAT 
CTAGGGACCA ATTTCTTCCT GTGTGAAGAT GATGTTGTTA ATGAGAGAAA CAGGGCTGAA 
GCTGTACTTC ATCGTATTGC AGAACTAAAT CCATATGTTC AGGTCTCATC ATCCTCTGCC 
CCTCTTGATG AAACCACAGA CCTCTCTTTC TTAGAAAAAT ATCAGTGTGT AGTATTGACT 
GAAATAAAAC TGACATTACA AAAGAAGATC AACAATTTTT GCCATTCTCA TTGCCCTCCA 
ATTAAGTTCA TTAGTGCAGA TGTACATGGA ATTTGGTCCA GGTTGTTTTG TGATTTTGGT 
GATGAATTTG AAGTTTCAGA TACAACAGGA GAAGAACCAA AAGAAATTTT CATTTCAAAC 
ATAACGCAAG CTAATCCAGG TATTGTCACT TGCCTTGAAA GTCATCCTCA CAAGCTTGAG 
ACAGGACAGT TCCTAACATT TCGAGAAATT CATGGAATGA CAGGCTTAAA TGGATCTGTA 
CAACAGATAA CTGTCATATC ACCATTTTCC TTCAGCATTG GTGATACTAC AAAACTGGAC 
CCATATTTAC ATGGAGGCAT AGCCGTGCAG GTGAAGACTC CTAAAACATT CTGCTTTGAA 
CCCCTGGAGA GCCAGATAAA ACATCCAAGG TGCCTTATTG CAGATTTTAG CAAACCTGAG 
GCACCTTTAG AGATTCATCT CGCTATGCTT GCCTTGGACC AGTTTCAGGA GAACTATAAC 
CGTAAGCCAA ATATCAGATG TCAGCAGGAT TCAGATGAAC TATTGAAGCT AACAGTATCT 
ATAAATGAAA CCTTGGAAGA GAAGCCTGAA GTGAATGCTG ACATTGTGCA CTGGCTTTCG 
TGGACTGCCC AAGGCTTTTT ACCACCACTC GCTGCTGCAG TTGGAGGTGT TGCTAGCCAA 
GAAGTCTTAA AAGCTGTGAC GGGGAAGTTC TCGCCCTTGT GTCAATGGTT GTACCTTGAA 
GCAGCAGATA CTGTGGAATC CCTAGGCAAT CCTGGGCATG AAGAGTTTCT CCCACGAGGA 
GATAGATATG ATGCCATACG TGCCTGCATT GGAAATACAT TGTGTCAGAA GCTACAAAAT 
TTGAATATCT TCTTAGTAGG ATGTGGTGCC ATAGGCTGTG AAATGTTAAA AAATTTTGCA 
TTACTGGGTG TTGGTACAGG CAGAGAGAAA GGAATGGTAA CAGTTACAGA TCCTGACTTG 
ATAGAAAAAT CCAATTTAAA CAGACAGTTC CTGTTTCGTC CTCATCACAT ACAGAAACCT 
AAAAGCTATA CTGCTGCTGA AGCAACTCTG AAAATAAATC CTCAATTAAA AATAGATGCA 
CACCTGAACA AAGTTTGTCC AGCCACTGAG AGTATATACA GTGATGAATT TTACACTAAG 
CAAGATATCA TTATTACAGC ACTAGATAAT GTGGAAGCCA GGAGATATGT AGACAGTCGC 
TGTTTAGCAA ATCTACGGCC TCTCTTAGAT TCTGGAACAA TGGGCACCAA GGGACATACT 
GAAATTATCG TACCTCAATT AACTGAATCT TATAATAGTC ATCGAGACCC CCCCGAAGAG 
GAAATACCAT TTTGCACTCT AAAGTCCTTT CCAGCAGCTA TCGAACATAC TATCCAGTGG 
GCAAGAGACA AGTTTGAAAG TTCCTTCTCC CACAAACCTT CACTGTTTAA CAAGTTTTGG 
CAAGCATATC CCTCTGCAGA AGATGTCTTA CAGAAGATAC AAAATGGACA AAGTTTAGAA 
GGCTGTTTTC AAGTTATTAA GCTACTTAGC AGAAGACCTA GAATTTGGTC CCAGTGTGTA 
GAGTTAGCAA GACTAAAGTT TGAAAAATAC TTTAACCATA AGGCTCTGCA GCTTCTTCAC 
TGTTTTCCTC TTGAGACAAG ACTAAAAGAT GGCAGTTTGT TTTGGCAATC ACCAAAAAGG 
CCGCCTTCTC CAATAAAATT TGATTTAAAT GAACCTTTGC ACCTCAGTTT TCTTCAGAGT 
GCTGCAAAAC TATATGCTAC AGTATATTGT ATTCCGTTTT CAGAAAAGGA CTTATCAGTG 
AATAGCCTCA TGGACATTCT TTCAGAAGTT AAAATTGAGG AATTCAAGCC TTCCAACAAG 
GTTGTTCAAA CAGACGAAAC TGCAAGGAAG CCCGACCATG TTCCTGTCTC CAGTGAAGAT 
GAAAGGAATG CTGTTTTCCA ACTAGAAGAG GCTCTTTCCT CTAACAAAGC TACCAAAAGT 
GACCTTCAGA TGACAGTGCT TTCATTTGAA AAAGATGATG ACCGTAATGG ACACATAGAT 
TTCATCACAG CTGCTTCCAA CCTTCGAGCC AAAATGTATA GCATTGAACC AGCTGACCGT 
TTTAAAACTA AACGCATAGC TGGTAAAATT ATACCTGCTA TAGCAACATC TACTGCTGCA 
GTTTCTGGCT TGGTTGCTTT GGAGATGATC AAGGTAGCTG GTGGCTATCC CTTCGACGCT 
TACAAAAACT GTTTCCTTAA TTTAGCCATT CCAATAATAG TGTTTACAGA GACATCTGAA 
GTAAGAAAAA CTGAAATCAG AAATGGAATA TCATTTACAA TTTGGGACAG ATGGACTGTA 
CATGGAAAAG AAGATTTCAC CCTCTCAGAT TTCATAAATG CTGTCAAAGA AAACTATGGA 
ATTGAGCCGA CAATGGTGGT GCAGGGAGTC AAAATGCTTT ATGTCCCTGT AATGCCAGGT 
CATGCAAAAA GGCTAAAGTT AACAATGCAC AAACTTGTGA AGCCTTCCAC TGAGAAGAAA 
TATGTGGATC TTACTGTGTC ATTTGCCCCA GACGCTGATG GAGATGAAGA TTTGCCCGGC 
CCTCCAGTGA GATACTACTT CAGTCATGAC ACTAATGAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_766300.1
CDS	6..3167
Translation	MERSEPLAVLSCEEASCSSWGACGASKNLPTMTTESLEIDDGLYSRQRYVLGDTAMQKMAKSCVFLSGMGGLGVEIAKNLVLAGIKALTIHDTKKCQAWDLGTNFFLCEDDVVNERNRAEAVLHRIAELNPYVQVSSSSAPLDETTDLSFLEKYQCVVLTEIKLTLQKKINNFCHSHCPPIKFISADVHGIWSRLFCDFGDEFEVSDTTGEEPKEIFISNITQANPGIVTCLESHPHKLETGQFLTFREIHGMTGLNGSVQQITVISPFSFSIGDTTKLDPYLHGGIAVQVKTPKTFCFEPLESQIKHPRCLIADFSKPEAPLEIHLAMLALDQFQENYNRKPNIRCQQDSDELLKLTVSINETLEEKPEVNADIVHWLSWTAQGFLPPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADTVESLGNPGHEEFLPRGDRYDAIRACIGNTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAEATLKINPQLKIDAHLNKVCPATESIYSDEFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEIIVPQLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQAYPSAEDVLQKIQNGQSLEGCFQVIKLLSRRPRIWSQCVELARLKFEKYFNHKALQLLHCFPLETRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQSAAKLYATVYCIPFSEKDLSVNSLMDILSEVKIEEFKPSNKVVQTDETARKPDHVPVSSEDERNAVFQLEEALSSNKATKSDLQMTVLSFEKDDDRNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATSTAAVSGLVALEMIKVAGGYPFDAYKNCFLNLAIPIIVFTETSEVRKTEIRNGISFTIWDRWTVHGKEDFTLSDFINAVKENYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPSTEKKYVDLTVSFAPDADGDEDLPGPPVRYYFSHDTNE

Target ORF information:

RefSeq Version	NM_172712.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin-like modifier activating enzyme 6 (Uba6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172712.2

ORF Insert Sequence:

ATGGAGCGGT CCGAGCCGTT GGCTGTGCTT TCCTGTGAAG AGGCGTCCTG CTCCTCCTGG 
GGAGCCTGCG GTGCAAGTAA AAATTTACCT ACCATGACAA CAGAATCTTT GGAAATCGAT 
GATGGATTAT ACAGTCGCCA GAGATATGTT CTTGGTGACA CAGCAATGCA GAAGATGGCC 
AAGTCCTGTG TCTTCTTAAG TGGTATGGGT GGTCTTGGAG TGGAAATTGC AAAGAATCTT 
GTTCTTGCAG GGATTAAGGC CCTAACAATT CATGATACAA AAAAATGCCA AGCATGGGAT 
CTAGGGACCA ATTTCTTCCT GTGTGAAGAT GATGTTGTTA ATGAGAGAAA CAGGGCTGAA 
GCTGTACTTC ATCGTATTGC AGAACTAAAT CCATATGTTC AGGTCTCATC ATCCTCTGCC 
CCTCTTGATG AAACCACAGA CCTCTCTTTC TTAGAAAAAT ATCAGTGTGT AGTATTGACT 
GAAATAAAAC TGACATTACA AAAGAAGATC AACAATTTTT GCCATTCTCA TTGCCCTCCA 
ATTAAGTTCA TTAGTGCAGA TGTACATGGA ATTTGGTCCA GGTTGTTTTG TGATTTTGGT 
GATGAATTTG AAGTTTCAGA TACAACAGGA GAAGAACCAA AAGAAATTTT CATTTCAAAC 
ATAACGCAAG CTAATCCAGG TATTGTCACT TGCCTTGAAA GTCATCCTCA CAAGCTTGAG 
ACAGGACAGT TCCTAACATT TCGAGAAATT CATGGAATGA CAGGCTTAAA TGGATCTGTA 
CAACAGATAA CTGTCATATC ACCATTTTCC TTCAGCATTG GTGATACTAC AAAACTGGAC 
CCATATTTAC ATGGAGGCAT AGCCGTGCAG GTGAAGACTC CTAAAACATT CTGCTTTGAA 
CCCCTGGAGA GCCAGATAAA ACATCCAAGG TGCCTTATTG CAGATTTTAG CAAACCTGAG 
GCACCTTTAG AGATTCATCT CGCTATGCTT GCCTTGGACC AGTTTCAGGA GAACTATAAC 
CGTAAGCCAA ATATCAGATG TCAGCAGGAT TCAGATGAAC TATTGAAGCT AACAGTATCT 
ATAAATGAAA CCTTGGAAGA GAAGCCTGAA GTGAATGCTG ACATTGTGCA CTGGCTTTCG 
TGGACTGCCC AAGGCTTTTT ACCACCACTC GCTGCTGCAG TTGGAGGTGT TGCTAGCCAA 
GAAGTCTTAA AAGCTGTGAC GGGGAAGTTC TCGCCCTTGT GTCAATGGTT GTACCTTGAA 
GCAGCAGATA CTGTGGAATC CCTAGGCAAT CCTGGGCATG AAGAGTTTCT CCCACGAGGA 
GATAGATATG ATGCCATACG TGCCTGCATT GGAAATACAT TGTGTCAGAA GCTACAAAAT 
TTGAATATCT TCTTAGTAGG ATGTGGTGCC ATAGGCTGTG AAATGTTAAA AAATTTTGCA 
TTACTGGGTG TTGGTACAGG CAGAGAGAAA GGAATGGTAA CAGTTACAGA TCCTGACTTG 
ATAGAAAAAT CCAATTTAAA CAGACAGTTC CTGTTTCGTC CTCATCACAT ACAGAAACCT 
AAAAGCTATA CTGCTGCTGA AGCAACTCTG AAAATAAATC CTCAATTAAA AATAGATGCA 
CACCTGAACA AAGTTTGTCC AGCCACTGAG AGTATATACA GTGATGAATT TTACACTAAG 
CAAGATATCA TTATTACAGC ACTAGATAAT GTGGAAGCCA GGAGATATGT AGACAGTCGC 
TGTTTAGCAA ATCTACGGCC TCTCTTAGAT TCTGGAACAA TGGGCACCAA GGGACATACT 
GAAATTATCG TACCTCAATT AACTGAATCT TATAATAGTC ATCGAGACCC CCCCGAAGAG 
GAAATACCAT TTTGCACTCT AAAGTCCTTT CCAGCAGCTA TCGAACATAC TATCCAGTGG 
GCAAGAGACA AGTTTGAAAG TTCCTTCTCC CACAAACCTT CACTGTTTAA CAAGTTTTGG 
CAAGCATATC CCTCTGCAGA AGATGTCTTA CAGAAGATAC AAAATGGACA AAGTTTAGAA 
GGCTGTTTTC AAGTTATTAA GCTACTTAGC AGAAGACCTA GAATTTGGTC CCAGTGTGTA 
GAGTTAGCAA GACTAAAGTT TGAAAAATAC TTTAACCATA AGGCTCTGCA GCTTCTTCAC 
TGTTTTCCTC TTGAGACAAG ACTAAAAGAT GGCAGTTTGT TTTGGCAATC ACCAAAAAGG 
CCGCCTTCTC CAATAAAATT TGATTTAAAT GAACCTTTGC ACCTCAGTTT TCTTCAGAGT 
GCTGCAAAAC TATATGCTAC AGTATATTGT ATTCCGTTTT CAGAAAAGGA CTTATCAGTG 
AATAGCCTCA TGGACATTCT TTCAGAAGTT AAAATTGAGG AATTCAAGCC TTCCAACAAG 
GTTGTTCAAA CAGACGAAAC TGCAAGGAAG CCCGACCATG TTCCTGTCTC CAGTGAAGAT 
GAAAGGAATG CTGTTTTCCA ACTAGAAGAG GCTCTTTCCT CTAACAAAGC TACCAAAAGT 
GACCTTCAGA TGACAGTGCT TTCATTTGAA AAAGATGATG ACCGTAATGG ACACATAGAT 
TTCATCACAG CTGCTTCCAA CCTTCGAGCC AAAATGTATA GCATTGAACC AGCTGACCGT 
TTTAAAACTA AACGCATAGC TGGTAAAATT ATACCTGCTA TAGCAACATC TACTGCTGCA 
GTTTCTGGCT TGGTTGCTTT GGAGATGATC AAGGTAGCTG GTGGCTATCC CTTCGACGCT 
TACAAAAACT GTTTCCTTAA TTTAGCCATT CCAATAATAG TGTTTACAGA GACATCTGAA 
GTAAGAAAAA CTGAAATCAG AAATGGAATA TCATTTACAA TTTGGGACAG ATGGACTGTA 
CATGGAAAAG AAGATTTCAC CCTCTCAGAT TTCATAAATG CTGTCAAAGA AAACTATGGA 
ATTGAGCCGA CAATGGTGGT GCAGGGAGTC AAAATGCTTT ATGTCCCTGT AATGCCAGGT 
CATGCAAAAA GGCTAAAGTT AACAATGCAC AAACTTGTGA AGCCTTCCAC TGAGAAGAAA 
TATGTGGATC TTACTGTGTC ATTTGCCCCA GACGCTGATG GAGATGAAGA TTTGCCCGGC 
CCTCCAGTGA GATACTACTT CAGTCATGAC ACTAATGAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Impairment of social behavior and communication in mice lacking the Uba6-dependent ubiquitin activation system.
Behavioural brain research28178-85(2015 Mar)
Lee JY,Kwak M,Lee PC

Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.
Molecular cell50(2)172-84(2013 Apr)
Lee PC,Dodart JC,Aron L,Finley LW,Bronson RT,Haigis MC,Yankner BA,Harper JW

Identification and expression of potential regulators of the mammalian mitotic-to-meiotic transition.
Biology of reproduction84(1)34-42(2011 Jan)
Hogarth CA,Mitchell D,Evanoff R,Small C,Griswold M

E1-L2 activates both ubiquitin and FAT10.
Molecular cell27(6)1014-23(2007 Sep)
Chiu YH,Sun Q,Chen ZJ

Identification of differentially expressed genes in mouse spermatogenesis.
Journal of andrology24(6)899-911(2003 Nov-Dec)
Pang AL,Taylor HC,Johnson W,Alexander S,Chen Y,Su YA,Li X,Ravindranath N,Dym M,Rennert OM,Chan WY

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Uba6 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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