Lclat1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lclat1
Entrez Gene ID	225010
Full Name	lysocardiolipin acyltransferase 1
Synonyms	AI181996,Agpat8,Alcat1,Gm91,Lycat
General protein information	Preferred Names lysocardiolipin acyltransferase 1 Names lysocardiolipin acyltransferase 1 acyl-CoA:lysocardiolipin acyltransferase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 E1.3-E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001177967.1	NP_001171438.1	lysocardiolipin acyltransferase 1
NM_001081071.2	NP_001074540.1	lysocardiolipin acyltransferase 1
NM_001177968.1	NP_001171439.1	lysocardiolipin acyltransferase 1
XM_011246410.2	XP_011244712.1	lysocardiolipin acyltransferase 1 isoform X1
XM_011246410.1	XP_011244712.1	lysocardiolipin acyltransferase 1 isoform X1
XM_011246410.3	XP_011244712.1	lysocardiolipin acyltransferase 1 isoform X1

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os01g0782500	NP_001044448.1
Oryza sativa (rice)	Os05g0502200	NP_001055974.1
Mus musculus (house mouse)	Lclat1	NP_001171439.1
Gallus gallus (chicken)	LCLAT1	NP_001026210.1
Caenorhabditis elegans (roundworm)	acl-8	NP_504643.1
Macaca mulatta (Rhesus monkey)	LCLAT1	XP_002799239.1
Canis lupus familiaris (dog)	LCLAT1	XP_005630367.1
Rattus norvegicus (Norway rat)	Lclat1	XP_006239842.1
Homo sapiens (human)	LCLAT1	NP_872357.2
Danio rerio (zebrafish)	lycat	NP_998435.1
Bos taurus (cattle)	LCLAT1	XP_002691491.1
Caenorhabditis elegans (roundworm)	acl-9	NP_504644.1
Caenorhabditis elegans (roundworm)	bus-18	NP_505971.2
Pan troglodytes (chimpanzee)	LCLAT1	XP_001163327.1
Arabidopsis thaliana (thale cress)	LPAT5	NP_001030724.2
Xenopus tropicalis (tropical clawed frog)	lclat1	NP_001135517.1

Gene Ontology
Bibliography

Related articles in PubMed

Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation.
Huang LS, Jiang P, Feghali-Bostwick C, Reddy SP, Garcia JGN, Natarajan V
Free radical biology & medicine112162-173(2017 11)

LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1.
Zou C, Synan MJ, Li J, Xiong S, Manni ML, Liu Y, Chen BB, Zhao Y, Shiva S, Tyurina YY, Jiang J, Lee JS, Das S, Ray A, Ray P, Kagan VE, Mallampalli RK
Journal of cell science129(1)51-64(2016 Jan)

Differential reduction in cardiac and liver monolysocardiolipin acyltransferase-1 and reduction in cardiac and liver tetralinoleoyl-cardiolipin in the α-subunit of trifunctional protein heterozygous knockout mice.
Mejia EM, Ibdah JA, Sparagna GC, Hatch GM
The Biochemical journal471(1)123-9(2015 Oct)

ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis.
Wang L, Liu X, Nie J, Zhang J, Kimball SR, Zhang H, Zhang WJ, Jefferson LS, Cheng Z, Ji Q, Shi Y
Hepatology (Baltimore, Md.)61(2)486-96(2015 Feb)

The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.
Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, Kotha SR, Gurney TO, Parinandi NL, Lussier YA, Garcia JG, Natarajan V
American journal of respiratory and critical care medicine189(11)1402-15(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lclat1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lclat1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01126	NM_001177968.1 Latest version!	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
OMu01126	NM_001177967.1 Latest version!	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
OMu01126	NM_001081071.2 Latest version!	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
OMu01126	XM_011246410.3 Latest version!	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
View Old Accession Versions >>
OMu01126	XM_011246410.1	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OMu01126	XM_011246410.2	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lclat1 ( XM_011246410.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244712.1 Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu01126
Clone ID Related Accession (Same CDS sequence)	NM_001177967.1 , NM_001081071.2 , NM_001177968.1 , XM_011246410.2 , XM_011246410.1 , XM_011246410.3
Accession Version	XM_011246410.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1423324800000
Organism	Mus musculus(House mouse)
Product	lysocardiolipin acyltransferase 1 isoform X1
Comment

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244712.1
Translation	MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE

Target ORF information:

RefSeq Version	XM_011246410.1
Organism	Mus musculus(House mouse)
Definition	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246410.1

ORF Insert Sequence:

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lclat1 ( NM_001177967.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171438.1 Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu01126
Clone ID Related Accession (Same CDS sequence)	NM_001177967.1 , NM_001081071.2 , NM_001177968.1 , XM_011246410.2 , XM_011246410.1 , XM_011246410.3
Accession Version	NM_001177967.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	lysocardiolipin acyltransferase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB868193.1, BC147499.1, AC112949.9 and AI847050.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC147499.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 19372376 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171438.1
CDS	177..1307
Translation	MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE

Target ORF information:

RefSeq Version	NM_001177967.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177967.1

ORF Insert Sequence:

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lclat1 ( NM_001081071.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001074540.1 Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu01126
Clone ID Related Accession (Same CDS sequence)	NM_001177967.1 , NM_001081071.2 , NM_001177968.1 , XM_011246410.2 , XM_011246410.1 , XM_011246410.3
Accession Version	NM_001081071.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	lysocardiolipin acyltransferase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB868193.1, BC158076.1, AC112949.9 and AI847050.1. On May 5, 2010 this sequence version replaced NM_001081071.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC158076.1, AK144580.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 19372376 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074540.1
CDS	198..1328
Translation	MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE

Target ORF information:

RefSeq Version	NM_001081071.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001081071.2

ORF Insert Sequence:

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lclat1 ( NM_001177968.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171439.1 Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu01126
Clone ID Related Accession (Same CDS sequence)	NM_001177967.1 , NM_001081071.2 , NM_001177968.1 , XM_011246410.2 , XM_011246410.1 , XM_011246410.3
Accession Version	NM_001177968.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	lysocardiolipin acyltransferase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB868193.1, BC150884.1, AC112949.9 and AI847050.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC150884.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 19372376 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171439.1
CDS	166..1296
Translation	MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE

Target ORF information:

RefSeq Version	NM_001177968.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177968.1

ORF Insert Sequence:

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lclat1 ( XM_011246410.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244712.1 Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu01126
Clone ID Related Accession (Same CDS sequence)	NM_001177967.1 , NM_001081071.2 , NM_001177968.1 , XM_011246410.2 , XM_011246410.1 , XM_011246410.3
Accession Version	XM_011246410.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	lysocardiolipin acyltransferase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011246410.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244712.1
CDS	391..1521
Translation	MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE

Target ORF information:

RefSeq Version	XM_011246410.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246410.2

ORF Insert Sequence:

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lclat1 ( XM_011246410.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011244712.1 Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu01126
Clone ID Related Accession (Same CDS sequence)	NM_001177967.1 , NM_001081071.2 , NM_001177968.1 , XM_011246410.2 , XM_011246410.1 , XM_011246410.3
Accession Version	XM_011246410.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	lysocardiolipin acyltransferase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011246410.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011244712.1
CDS	2996..4126
Translation	MVSWKGIYFILFLFAGSFFGSIFMLGPILPLMFINLSWYRWISSRLVATWLTLPVALLETMFGVRVVITGDAFVPGERSVIIMNHRTRVDWMFLWNCLMRYSYLRVEKICLKSSLKSVPGFGWAMQVAAFIFIHRKWKDDKSHFEDMIDYFCAIHEPLQLLIFPEGTDLTENNKARSNDFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPYNIPQTEKHLLLGDFPKEIHFHVQRYPADSLPTSKEDLQLWCHRRWEEKEERLRSFYQGEKNFHFTGQSTVPPCKSELRVLVVKLLSIVYWALFCSAMCLLIYLYSPVRWYFIISIVFFVLQERIFGGLEIIELACYRFLHKHPHLNSKKNE

Target ORF information:

RefSeq Version	XM_011246410.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysocardiolipin acyltransferase 1 (Lclat1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011246410.3

ORF Insert Sequence:

ATGGTGTCAT GGAAGGGGAT TTACTTTATA CTCTTCCTGT TTGCTGGAAG CTTTTTTGGA 
AGTATTTTTA TGCTCGGCCC CATTTTACCT TTGATGTTTA TAAACCTGTC GTGGTATCGC 
TGGATTAGCA GCCGTCTTGT GGCTACATGG CTCACACTTC CTGTGGCATT GCTGGAGACC 
ATGTTTGGTG TGAGAGTGGT TATAACAGGT GACGCCTTTG TGCCTGGAGA GCGGAGCGTC 
ATCATCATGA ACCACCGGAC ACGTGTGGAC TGGATGTTCC TGTGGAACTG TCTAATGAGG 
TACAGCTACC TCAGGGTGGA GAAGATTTGC CTCAAATCCA GTCTCAAAAG TGTTCCTGGA 
TTCGGCTGGG CCATGCAAGT TGCGGCCTTT ATCTTTATTC ATAGGAAGTG GAAGGATGAT 
AAGAGCCATT TTGAAGACAT GATTGATTAT TTTTGTGCCA TCCATGAACC ACTACAGCTT 
CTCATTTTTC CAGAAGGAAC TGACCTCACA GAAAATAATA AGGCTAGGAG TAATGATTTT 
GCTGAGAAGA ACGGACTTCA GAAATATGAG TATGTTTTAC ACCCAAGAAC CACTGGCTTT 
ACCTTTGTGG TGGACCGCCT AAGAGAAGGG AAGAACCTCG ATGCTGTTCA TGACATCACG 
GTCGCATATC CTTACAACAT CCCTCAAACT GAGAAGCACC TTCTCCTTGG AGACTTTCCC 
AAGGAGATCC ACTTCCACGT CCAGCGGTAT CCAGCTGACT CTCTTCCCAC ATCCAAGGAG 
GACCTTCAGC TCTGGTGCCA CAGAAGGTGG GAAGAAAAGG AGGAGAGGCT TCGGTCCTTC 
TACCAAGGAG AGAAAAACTT CCACTTTACT GGGCAGAGTA CAGTTCCACC TTGCAAGTCT 
GAGCTCAGAG TCCTTGTGGT CAAGCTACTG TCCATAGTGT ACTGGGCCTT GTTCTGCTCT 
GCAATGTGCC TGCTCATATA TCTGTACAGC CCTGTTCGGT GGTATTTTAT AATCAGCATT 
GTGTTCTTCG TGCTGCAGGA GAGAATATTT GGTGGACTGG AAATCATTGA ACTTGCATGT 
TACCGTTTTT TACACAAGCA CCCACATTTA AATTCAAAGA AAAATGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation.
Free radical biology & medicine112162-173(2017 11)
Huang LS,Jiang P,Feghali-Bostwick C,Reddy SP,Garcia JGN,Natarajan V

LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1.
Journal of cell science129(1)51-64(2016 Jan)
Zou C,Synan MJ,Li J,Xiong S,Manni ML,Liu Y,Chen BB,Zhao Y,Shiva S,Tyurina YY,Jiang J,Lee JS,Das S,Ray A,Ray P,Kagan VE,Mallampalli RK

Differential reduction in cardiac and liver monolysocardiolipin acyltransferase-1 and reduction in cardiac and liver tetralinoleoyl-cardiolipin in the α-subunit of trifunctional protein heterozygous knockout mice.
The Biochemical journal471(1)123-9(2015 Oct)
Mejia EM,Ibdah JA,Sparagna GC,Hatch GM

ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis.
Hepatology (Baltimore, Md.)61(2)486-96(2015 Feb)
Wang L,Liu X,Nie J,Zhang J,Kimball SR,Zhang H,Zhang WJ,Jefferson LS,Cheng Z,Ji Q,Shi Y

The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.
American journal of respiratory and critical care medicine189(11)1402-15(2014 Jun)
Huang LS,Mathew B,Li H,Zhao Y,Ma SF,Noth I,Reddy SP,Harijith A,Usatyuk PV,Berdyshev EV,Kaminski N,Zhou T,Zhang W,Zhang Y,Rehman J,Kotha SR,Gurney TO,Parinandi NL,Lussier YA,Garcia JG,Natarajan V

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Lclat1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM