PLSCR1 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLSCR1
Entrez Gene ID	22038
Full Name	phospholipid scramblase 1
Synonyms	MmTRA1a,MmTRA1b,Nor1,Tra1,Tra1a,Tra1b,Tras1,Tras2
General protein information	Preferred Names phospholipid scramblase 1 Names phospholipid scramblase 1 PL scramblase 1 ca(2+)-dependent phospholipid scramblase 1 transplantability-associated protein 1
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 9 Map Location: 9\|9 E3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_011636.2	NP_035766.2	phospholipid scramblase 1
XM_006511052.4	XP_006511115.1	phospholipid scramblase 1 isoform X1
XM_006511052.3	XP_006511115.1	phospholipid scramblase 1 isoform X1
XM_006511052.2	XP_006511115.1	phospholipid scramblase 1 isoform X1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005498	XP_001688666.1
Danio rerio (zebrafish)	plscr3a	NP_001098583.1
Homo sapiens (human)	PLSCR1	NP_066928.1
Rattus norvegicus (Norway rat)	Plscr1	NP_476542.1
Drosophila melanogaster (fruit fly)	scramb1	NP_648389.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005504	XP_001688668.1
Caenorhabditis elegans (roundworm)	scrm-3	NP_503934.2
Xenopus tropicalis (tropical clawed frog)	LOC100489273	XP_002938452.2
Pan troglodytes (chimpanzee)	PLSCR1	XP_001135229.2
Macaca mulatta (Rhesus monkey)	PLSCR1	XP_001111222.1
Mus musculus (house mouse)	Plscr1	NP_035766.2
Gallus gallus (chicken)	PLSCR1	XP_001231237.1
Danio rerio (zebrafish)	plscr3b	NP_998031.1
Caenorhabditis elegans (roundworm)	scrm-2	NP_493321.1
Xenopus tropicalis (tropical clawed frog)	plscr1	NP_001135607.1
Canis lupus familiaris (dog)	LOC611500	XP_005634707.1
Caenorhabditis elegans (roundworm)	scrm-1	NP_492976.2

Gene Ontology
Bibliography

Related articles in PubMed

Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development.
Su X, Wu C, Ye X, Zeng M, Zhang Z, Che Y, Zhang Y, Liu L, Lin Y, Yang R
Cell death & disease9(3)302(2018 02)

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia.
Tufail Y, Cook D, Fourgeaud L, Powers CJ, Merten K, Clark CL, Hoffman E, Ngo A, Sekiguchi KJ, O'Shea CC, Lemke G, Nimmerjahn A
Neuron93(3)574-586.e8(2017 Feb)

Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo.
Kassas-Guediri A, Coudrat J, Pacreau E, Launay P, Monteiro RC, Blank U, Charles N, Benhamou M
PloS one12(3)e0173815(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase.
Pastorelli C, Veiga J, Charles N, Voignier E, Moussu H, Monteiro RC, Benhamou M
The Journal of biological chemistry276(23)20407-12(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PLSCR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLSCR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu08499	NM_011636.2 Latest version!	Mus musculus phospholipid scramblase 1 (Plscr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu08499	XM_006511052.4 Latest version!	Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu08499	XM_006511052.3	Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu08499	XM_006511052.2	Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLSCR1 ( NM_011636.2 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_035766.2 Mus musculus phospholipid scramblase 1 (Plscr1), mRNA.

Price & Availability↑

CloneID	OMu08499
Clone ID Related Accession (Same CDS sequence)	NM_011636.2 , XM_006511052.4 , XM_006511052.3 , XM_006511052.2
Accession Version	NM_011636.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	phospholipid scramblase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK788898.1, AF159593.1, AK003628.1 and CJ213207.1. On Jul 19, 2008 this sequence version replaced NM_011636.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK003628.1, AF159593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035766.2
CDS	182..1168
Translation	MENHSKQTEAPHPGTYMPAGYPPPYPPAAFQGPSDHAAYPIPQAGYQGPPGPYPGPQPGYPVPPGGYAGGGPSGFPVQNQPAYNHPGGPGGTPWMPAPPPPLNCPPGLEYLAQIDQLLVHQQIELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDCCTRNCCGASRPFTLRILDNLGREVMTLERPLRCSSCCFPCCLQEIEIQAPPGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLDEESVVGKISKQWSGFVREAFTDADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFERTGNEEQRSGAWQ

Target ORF information:

RefSeq Version	NM_011636.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipid scramblase 1 (Plscr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011636.2

ORF Insert Sequence:

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLSCR1 ( XM_006511052.4 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006511115.1 Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu08499
Clone ID Related Accession (Same CDS sequence)	NM_011636.2 , XM_006511052.4 , XM_006511052.3 , XM_006511052.2
Accession Version	XM_006511052.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	phospholipid scramblase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006511052.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511115.1
CDS	105..1091
Translation	MENHSKQTEAPHPGTYMPAGYPPPYPPAAFQGPSDHAAYPIPQAGYQGPPGPYPGPQPGYPVPPGGYAGGGPSGFPVQNQPAYNHPGGPGGTPWMPAPPPPLNCPPGLEYLAQIDQLLVHQQIELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDCCTRNCCGASRPFTLRILDNLGREVMTLERPLRCSSCCFPCCLQEIEIQAPPGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLDEESVVGKISKQWSGFVREAFTDADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFERTGNEEQRSGAWQ

Target ORF information:

RefSeq Version	XM_006511052.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511052.4

ORF Insert Sequence:

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLSCR1 ( XM_006511052.3 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006511115.1 Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu08499
Clone ID Related Accession (Same CDS sequence)	NM_011636.2 , XM_006511052.4 , XM_006511052.3 , XM_006511052.2
Accession Version	XM_006511052.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	phospholipid scramblase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006511052.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511115.1
CDS	236..1222
Translation	MENHSKQTEAPHPGTYMPAGYPPPYPPAAFQGPSDHAAYPIPQAGYQGPPGPYPGPQPGYPVPPGGYAGGGPSGFPVQNQPAYNHPGGPGGTPWMPAPPPPLNCPPGLEYLAQIDQLLVHQQIELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDCCTRNCCGASRPFTLRILDNLGREVMTLERPLRCSSCCFPCCLQEIEIQAPPGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLDEESVVGKISKQWSGFVREAFTDADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFERTGNEEQRSGAWQ

Target ORF information:

RefSeq Version	XM_006511052.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511052.3

ORF Insert Sequence:

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLSCR1 ( XM_006511052.2 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006511115.1 Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu08499
Clone ID Related Accession (Same CDS sequence)	NM_011636.2 , XM_006511052.4 , XM_006511052.3 , XM_006511052.2
Accession Version	XM_006511052.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1423324800000
Organism	Mus musculus(House mouse)
Product	phospholipid scramblase 1 isoform X1
Comment

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006511115.1
Translation	MENHSKQTEAPHPGTYMPAGYPPPYPPAAFQGPSDHAAYPIPQAGYQGPPGPYPGPQPGYPVPPGGYAGGGPSGFPVQNQPAYNHPGGPGGTPWMPAPPPPLNCPPGLEYLAQIDQLLVHQQIELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDCCTRNCCGASRPFTLRILDNLGREVMTLERPLRCSSCCFPCCLQEIEIQAPPGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLDEESVVGKISKQWSGFVREAFTDADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFERTGNEEQRSGAWQ

Target ORF information:

RefSeq Version	XM_006511052.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus phospholipid scramblase 1 (Plscr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006511052.2

ORF Insert Sequence:

ATGGAAAACC ACAGCAAGCA AACTGAGGCT CCCCACCCGG GAACATATAT GCCAGCTGGG 
TATCCCCCTC CGTATCCACC AGCAGCTTTC CAAGGACCTT CAGACCATGC TGCTTACCCC 
ATACCCCAGG CTGGCTACCA AGGGCCTCCG GGCCCCTATC CAGGGCCCCA ACCTGGCTAC 
CCAGTCCCAC CAGGAGGTTA TGCAGGTGGT GGCCCTAGTG GCTTTCCTGT CCAAAATCAG 
CCAGCATATA ATCATCCAGG TGGGCCTGGG GGGACCCCAT GGATGCCAGC CCCCCCTCCT 
CCACTGAACT GTCCACCGGG GCTGGAATAC TTAGCTCAGA TTGATCAGCT TCTGGTTCAT 
CAGCAAATTG AGCTTCTGGA AGTCTTAACA GGCTTTGAAA CAAATAACAA ATATGAAATC 
AAGAACAGCC TCGGGCAGAG AGTTTACTTT GCAGTGGAAG ATACTGACTG CTGTACCCGA 
AACTGCTGTG GGGCGTCTAG ACCTTTCACC TTGAGGATCC TGGATAATCT GGGCCGAGAA 
GTCATGACTC TGGAGAGACC TCTGAGATGC AGTAGCTGCT GCTTCCCCTG CTGCCTCCAG 
GAGATAGAAA TCCAGGCTCC TCCTGGGGTA CCAGTAGGTT ATGTGACTCA GACCTGGCAC 
CCATGTCTGC CCAAGTTCAC TCTCCAAAAT GAGAAGAAGC AGGATGTCCT GAAAGTAGTT 
GGTCCGTGTG TTGTGTGTAG CTGCTGTTCC GACATTGACT TTGAGCTCAA ATCTCTAGAT 
GAAGAATCAG TAGTTGGCAA AATTTCTAAG CAGTGGTCTG GTTTTGTGAG AGAGGCCTTC 
ACGGATGCAG ACAATTTTGG GATCCAGTTC CCGCTAGACC TGGATGTGAA GATGAAAGCT 
GTGATGCTTG GTGCTTGTTT CCTCATAGAT TTCATGTTTT TTGAAAGAAC TGGAAACGAG 
GAGCAAAGAT CAGGAGCATG GCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development.
Cell death & disease9(3)302(2018 02)
Su X,Wu C,Ye X,Zeng M,Zhang Z,Che Y,Zhang Y,Liu L,Lin Y,Yang R

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia.
Neuron93(3)574-586.e8(2017 Feb)
Tufail Y,Cook D,Fourgeaud L,Powers CJ,Merten K,Clark CL,Hoffman E,Ngo A,Sekiguchi KJ,O'Shea CC,Lemke G,Nimmerjahn A

Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo.
PloS one12(3)e0173815(2017)
Kassas-Guediri A,Coudrat J,Pacreau E,Launay P,Monteiro RC,Blank U,Charles N,Benhamou M

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase.
The Journal of biological chemistry276(23)20407-12(2001 Jun)
Pastorelli C,Veiga J,Charles N,Voignier E,Moussu H,Monteiro RC,Benhamou M

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PLSCR1 cDNA ORF clone, Mus musculus(House mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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