Kdm5a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdm5a
Entrez Gene ID	214899
Full Name	lysine (K)-specific demethylase 5A
Synonyms	AA409370,C76986,Jarid1a,RBP2,Rbbp2
General protein information	Preferred Names lysine (K)-specific demethylase 5A Names lysine-specific demethylase 5A RBBP-2 histone demethylase JARID1A jumonji, AT rich interactive domain 1A (Rbp2 like) jumonji/ARID domain-containing protein 1A retinoblastoma binding protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 F1\|6 56.95 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_145997.2	NP_666109.2	lysine-specific demethylase 5A
XM_011241281.3	XP_011239583.1	lysine-specific demethylase 5A isoform X1
XM_011241281.2	XP_011239583.1	lysine-specific demethylase 5A isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KDM5A	XP_005637389.1
Mus musculus (house mouse)	Kdm5a	NP_666109.2
Xenopus tropicalis (tropical clawed frog)	kdm5a	XP_002941946.2
Homo sapiens (human)	KDM5A	NP_001036068.1
Pan troglodytes (chimpanzee)	KDM5A	XP_003313474.1
Rattus norvegicus (Norway rat)	Kdm5a	NP_001264106.1
Gallus gallus (chicken)	KDM5A	XP_004937981.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004854	XP_314337.4
Macaca mulatta (Rhesus monkey)	KDM5A	XP_002798486.1
Drosophila melanogaster (fruit fly)	lid	NP_001245909.1
Bos taurus (cattle)	KDM5A	NP_001192554.1
Danio rerio (zebrafish)	kdm5a	XP_003201688.2

Gene Ontology
Bibliography

Related articles in PubMed

HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner.
Dreval K, Lake RJ, Fan HY
Nucleic acids research47(9)4521-4538(2019 05)

Autochthonous tumors driven by
McBrayer SK, Olenchock BA, DiNatale GJ, Shi DD, Khanal J, Jennings RB, Novak JS, Oser MG, Robbins AK, Modiste R, Bonal D, Moslehi J, Bronson RT, Neuberg D, Nguyen QD, Signoretti S, Losman JA, Kaelin WG Jr
Proceedings of the National Academy of Sciences of the United States of America115(16)E3741-E3748(2018 04)

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.
Elsen GE, Bedogni F, Hodge RD, Bammler TK, MacDonald JW, Lindtner S, Rubenstein JLR, Hevner RF
Frontiers in neuroscience12571(2018)

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A
Nature537(7621)548-552(2016 09)

KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis.
Wang C, Wang J, Li J, Hu G, Shan S, Li Q, Zhang X
Cell death & disease7(8)e2335(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kdm5a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm5a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu72902	XM_011241281.3 Latest version!	Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu13635	NM_145997.2 Latest version!	Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00
View Old Accession Versions >>
OMu72902	XM_011241281.2	Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdm5a ( XM_011241281.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239583.1 Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu72902
Clone ID Related Accession (Same CDS sequence)	XM_011241281.3 , XM_011241281.2
Accession Version	XM_011241281.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2616bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 5A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241281.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTCCG TGGGCCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC CGAGTGCCCG 
GTCTTTGAGC CCAGTTGGGA GGAGTTCACA GACCCGCTGA GTTTTATCGG GCGCATCCGG 
CCCTTTGCGG AGAAAACGGG CATCTGCAAA ATCCGGCCAC CCAAGGATTG GCAACCTCCA 
TTTGCCTGTG AAGTAAAAAC CTTCCGTTTC ACTCCTAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CTAGAGTAAG ATTGGACTTC TTGGATCAAC TGGCAAAATT TTGGGAACTT 
CAAGGATCTA CATTGAAGAT CCCTGTGGTG GAGAGAAAAA TCCTGGATTT GTATGCTTTA 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATAGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GCCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CACTATGAAA GAATTCTCTA CCCATATGAA CTTTTCCAAT CTGGTGTCAG CCTTATGGGT 
GTACAAATGC CTGATTTAGA TCTTAAAGAA AAAGTTGAGG CTGAGGTTCT CAGCACTGAC 
ATCCAGCCTT CCCCAGAGCG GGGAACAAGA ATGAATATTC CACCAAAGAG AACAAGACGA 
GTTAAGTCTC AGTCAGACTC TGGAGAAGTA AATAGAAACA CAGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGACCCAA AGTTGTGGGC CTGGCAGTAG GAGCAAAAGA TAAAGAAGAT 
GAAGTCACCC GAAGAAGAAA AGTTACCAAC AGGTCAGATG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GAACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGCAT GTTTTGTGGT 
CGAGGAAATA ATGAGGATAA ACTGCTTTTG TGTGATGGGT GCGATGACAG CTATCATACA 
TTTTGTCTAC TTCCACCACT ACCTGATGTC CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTTGCTGAGG AATGTAACAA ACCTCGAGAA GCCTTTGGAT TTGAGCAAGC TGTAAGAGAA 
TATACACTTC AAAGCTTTGG AGAGATGGCA GATAATTTTA AATCTGATTA TTTCAATATG 
CCAGTCCATA TGGTTCCTAC AGAGCTAGTA GAAAAAGAAT TCTGGCGGCT AGTAAGTAGC 
ATTGAAGAAG ATGTTATTGT AGAGTATGGA GCTGATATCT CTTCAAAAGA TTTTGGAAGT 
GGATTTCCTA AAAAGGATGG TCAAAGAAAG ATGTTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTT CTGGAGCAGT CCGTTCTTGC ACATATTAAT 
GTGGACATTT CTGGTATGAA GGTGCCATGG CTCTATGTGG GAATGTGCTT TTCTTCTTTT 
TGCTGGCATA TTGAAGATCA CTGGAGTTAT TCCATTAACT ACTTGCATTG GGGCGAGCCA 
AAGACATGGT ATGGTGTACC ATCTCATGCT GCAGAACAAC TGGAGGAGGT GATGAGGGAG 
CTGGCCCCTG AGTTATTTGA ATCCCAGCCT GATCTCCTAC ATCAGTTAGT AACCATCATG 
AACCCAAATG TGCTCATGGA GCATGGTGTG CCTGTGTACA GGACTAATCA GTGTGCTGGA 
GAGTTTGTGG TGACGTTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG ATACAACTTT 
GCCGAAGCGG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA GTGTGTAAAT 
CACTATCGAC GGCTCAGGCG CCATTGTGTC TTTTCACATG AGGAACTCAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTATGCAA AGAGTTGACT 
CTCATGACTG AAGAAGAAAC ACGATTGAGA GAATCAGTTG TTCAAATGGG TGTCGTGATG 
TCAGAAGAAG AAGTCTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACTACATGTT TTCTCTCAGC TCTCACATGC TCCTGTAATC CGGAGCGACT TGTATGTCTG 
TATCATCCAA CTGATTTGTG CTCTTGCCCC ATGCAGAACA AATGTCTTAG GTACCGCTAT 
CCACTAGAAG ACCTTCCATC TCTGCTTTAT GGTGTCAAAG TGAGAGCACA ATCCTATGAC 
ACTTGGGTCA ATCGTGTTAC AGAAGCATTG TCAGCTAGCT TCAACCATAA GAAAGATTTG 
ATTGAATTGA GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAGC TCAGGGACGC GGTGAAAGAA GCTGAGACCT GTGGTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAAAA ACACAGGCAG AGCTCAGACC TGTTTCAAAA TAAGTGTACG 
TGTAAAAGAT TTTGGGGGAC TGAAGAGTTG GCTCCATGGT TAAGAGCACT GACTGTTCTT 
GCAGAGGTCC CAGGTTCAGT TCCCAGTACT CACATGGCTT CAGTTCAAGA GATCTATGTA 
TGCCCTTGCT CCTCCTTGAG CACCACACTC ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239583.1
CDS	491..3106
Translation	MASVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPFAEKTGICKIRPPKDWQPPFACEVKTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPPKRTRRVKSQSDSGEVNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPKKDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALSASFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDLFQNKCTCKRFWGTEELAPWLRALTVLAEVPGSVPSTHMASVQEIYVCPCSSLSTTLM

Target ORF information:

RefSeq Version	XM_011241281.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241281.3

ORF Insert Sequence:

ATGGCGTCCG TGGGCCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC CGAGTGCCCG 
GTCTTTGAGC CCAGTTGGGA GGAGTTCACA GACCCGCTGA GTTTTATCGG GCGCATCCGG 
CCCTTTGCGG AGAAAACGGG CATCTGCAAA ATCCGGCCAC CCAAGGATTG GCAACCTCCA 
TTTGCCTGTG AAGTAAAAAC CTTCCGTTTC ACTCCTAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CTAGAGTAAG ATTGGACTTC TTGGATCAAC TGGCAAAATT TTGGGAACTT 
CAAGGATCTA CATTGAAGAT CCCTGTGGTG GAGAGAAAAA TCCTGGATTT GTATGCTTTA 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATAGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GCCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CACTATGAAA GAATTCTCTA CCCATATGAA CTTTTCCAAT CTGGTGTCAG CCTTATGGGT 
GTACAAATGC CTGATTTAGA TCTTAAAGAA AAAGTTGAGG CTGAGGTTCT CAGCACTGAC 
ATCCAGCCTT CCCCAGAGCG GGGAACAAGA ATGAATATTC CACCAAAGAG AACAAGACGA 
GTTAAGTCTC AGTCAGACTC TGGAGAAGTA AATAGAAACA CAGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGACCCAA AGTTGTGGGC CTGGCAGTAG GAGCAAAAGA TAAAGAAGAT 
GAAGTCACCC GAAGAAGAAA AGTTACCAAC AGGTCAGATG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GAACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGCAT GTTTTGTGGT 
CGAGGAAATA ATGAGGATAA ACTGCTTTTG TGTGATGGGT GCGATGACAG CTATCATACA 
TTTTGTCTAC TTCCACCACT ACCTGATGTC CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTTGCTGAGG AATGTAACAA ACCTCGAGAA GCCTTTGGAT TTGAGCAAGC TGTAAGAGAA 
TATACACTTC AAAGCTTTGG AGAGATGGCA GATAATTTTA AATCTGATTA TTTCAATATG 
CCAGTCCATA TGGTTCCTAC AGAGCTAGTA GAAAAAGAAT TCTGGCGGCT AGTAAGTAGC 
ATTGAAGAAG ATGTTATTGT AGAGTATGGA GCTGATATCT CTTCAAAAGA TTTTGGAAGT 
GGATTTCCTA AAAAGGATGG TCAAAGAAAG ATGTTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTT CTGGAGCAGT CCGTTCTTGC ACATATTAAT 
GTGGACATTT CTGGTATGAA GGTGCCATGG CTCTATGTGG GAATGTGCTT TTCTTCTTTT 
TGCTGGCATA TTGAAGATCA CTGGAGTTAT TCCATTAACT ACTTGCATTG GGGCGAGCCA 
AAGACATGGT ATGGTGTACC ATCTCATGCT GCAGAACAAC TGGAGGAGGT GATGAGGGAG 
CTGGCCCCTG AGTTATTTGA ATCCCAGCCT GATCTCCTAC ATCAGTTAGT AACCATCATG 
AACCCAAATG TGCTCATGGA GCATGGTGTG CCTGTGTACA GGACTAATCA GTGTGCTGGA 
GAGTTTGTGG TGACGTTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG ATACAACTTT 
GCCGAAGCGG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA GTGTGTAAAT 
CACTATCGAC GGCTCAGGCG CCATTGTGTC TTTTCACATG AGGAACTCAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTATGCAA AGAGTTGACT 
CTCATGACTG AAGAAGAAAC ACGATTGAGA GAATCAGTTG TTCAAATGGG TGTCGTGATG 
TCAGAAGAAG AAGTCTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACTACATGTT TTCTCTCAGC TCTCACATGC TCCTGTAATC CGGAGCGACT TGTATGTCTG 
TATCATCCAA CTGATTTGTG CTCTTGCCCC ATGCAGAACA AATGTCTTAG GTACCGCTAT 
CCACTAGAAG ACCTTCCATC TCTGCTTTAT GGTGTCAAAG TGAGAGCACA ATCCTATGAC 
ACTTGGGTCA ATCGTGTTAC AGAAGCATTG TCAGCTAGCT TCAACCATAA GAAAGATTTG 
ATTGAATTGA GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAGC TCAGGGACGC GGTGAAAGAA GCTGAGACCT GTGGTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAAAA ACACAGGCAG AGCTCAGACC TGTTTCAAAA TAAGTGTACG 
TGTAAAAGAT TTTGGGGGAC TGAAGAGTTG GCTCCATGGT TAAGAGCACT GACTGTTCTT 
GCAGAGGTCC CAGGTTCAGT TCCCAGTACT CACATGGCTT CAGTTCAAGA GATCTATGTA 
TGCCCTTGCT CCTCCTTGAG CACCACACTC ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm5a ( XM_011241281.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239583.1 Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu72902
Clone ID Related Accession (Same CDS sequence)	XM_011241281.3 , XM_011241281.2
Accession Version	XM_011241281.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2616bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 5A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241281.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTCCG TGGGCCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC CGAGTGCCCG 
GTCTTTGAGC CCAGTTGGGA GGAGTTCACA GACCCGCTGA GTTTTATCGG GCGCATCCGG 
CCCTTTGCGG AGAAAACGGG CATCTGCAAA ATCCGGCCAC CCAAGGATTG GCAACCTCCA 
TTTGCCTGTG AAGTAAAAAC CTTCCGTTTC ACTCCTAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CTAGAGTAAG ATTGGACTTC TTGGATCAAC TGGCAAAATT TTGGGAACTT 
CAAGGATCTA CATTGAAGAT CCCTGTGGTG GAGAGAAAAA TCCTGGATTT GTATGCTTTA 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATAGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GCCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CACTATGAAA GAATTCTCTA CCCATATGAA CTTTTCCAAT CTGGTGTCAG CCTTATGGGT 
GTACAAATGC CTGATTTAGA TCTTAAAGAA AAAGTTGAGG CTGAGGTTCT CAGCACTGAC 
ATCCAGCCTT CCCCAGAGCG GGGAACAAGA ATGAATATTC CACCAAAGAG AACAAGACGA 
GTTAAGTCTC AGTCAGACTC TGGAGAAGTA AATAGAAACA CAGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGACCCAA AGTTGTGGGC CTGGCAGTAG GAGCAAAAGA TAAAGAAGAT 
GAAGTCACCC GAAGAAGAAA AGTTACCAAC AGGTCAGATG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GAACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGCAT GTTTTGTGGT 
CGAGGAAATA ATGAGGATAA ACTGCTTTTG TGTGATGGGT GCGATGACAG CTATCATACA 
TTTTGTCTAC TTCCACCACT ACCTGATGTC CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTTGCTGAGG AATGTAACAA ACCTCGAGAA GCCTTTGGAT TTGAGCAAGC TGTAAGAGAA 
TATACACTTC AAAGCTTTGG AGAGATGGCA GATAATTTTA AATCTGATTA TTTCAATATG 
CCAGTCCATA TGGTTCCTAC AGAGCTAGTA GAAAAAGAAT TCTGGCGGCT AGTAAGTAGC 
ATTGAAGAAG ATGTTATTGT AGAGTATGGA GCTGATATCT CTTCAAAAGA TTTTGGAAGT 
GGATTTCCTA AAAAGGATGG TCAAAGAAAG ATGTTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTT CTGGAGCAGT CCGTTCTTGC ACATATTAAT 
GTGGACATTT CTGGTATGAA GGTGCCATGG CTCTATGTGG GAATGTGCTT TTCTTCTTTT 
TGCTGGCATA TTGAAGATCA CTGGAGTTAT TCCATTAACT ACTTGCATTG GGGCGAGCCA 
AAGACATGGT ATGGTGTACC ATCTCATGCT GCAGAACAAC TGGAGGAGGT GATGAGGGAG 
CTGGCCCCTG AGTTATTTGA ATCCCAGCCT GATCTCCTAC ATCAGTTAGT AACCATCATG 
AACCCAAATG TGCTCATGGA GCATGGTGTG CCTGTGTACA GGACTAATCA GTGTGCTGGA 
GAGTTTGTGG TGACGTTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG ATACAACTTT 
GCCGAAGCGG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA GTGTGTAAAT 
CACTATCGAC GGCTCAGGCG CCATTGTGTC TTTTCACATG AGGAACTCAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTATGCAA AGAGTTGACT 
CTCATGACTG AAGAAGAAAC ACGATTGAGA GAATCAGTTG TTCAAATGGG TGTCGTGATG 
TCAGAAGAAG AAGTCTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACTACATGTT TTCTCTCAGC TCTCACATGC TCCTGTAATC CGGAGCGACT TGTATGTCTG 
TATCATCCAA CTGATTTGTG CTCTTGCCCC ATGCAGAACA AATGTCTTAG GTACCGCTAT 
CCACTAGAAG ACCTTCCATC TCTGCTTTAT GGTGTCAAAG TGAGAGCACA ATCCTATGAC 
ACTTGGGTCA ATCGTGTTAC AGAAGCATTG TCAGCTAGCT TCAACCATAA GAAAGATTTG 
ATTGAATTGA GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAGC TCAGGGACGC GGTGAAAGAA GCTGAGACCT GTGGTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAAAA ACACAGGCAG AGCTCAGACC TGTTTCAAAA TAAGTGTACG 
TGTAAAAGAT TTTGGGGGAC TGAAGAGTTG GCTCCATGGT TAAGAGCACT GACTGTTCTT 
GCAGAGGTCC CAGGTTCAGT TCCCAGTACT CACATGGCTT CAGTTCAAGA GATCTATGTA 
TGCCCTTGCT CCTCCTTGAG CACCACACTC ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239583.1
CDS	392..3007
Translation	MASVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPFAEKTGICKIRPPKDWQPPFACEVKTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPPKRTRRVKSQSDSGEVNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPKKDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALSASFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDLFQNKCTCKRFWGTEELAPWLRALTVLAEVPGSVPSTHMASVQEIYVCPCSSLSTTLM

Target ORF information:

RefSeq Version	XM_011241281.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241281.2

ORF Insert Sequence:

ATGGCGTCCG TGGGCCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC CGAGTGCCCG 
GTCTTTGAGC CCAGTTGGGA GGAGTTCACA GACCCGCTGA GTTTTATCGG GCGCATCCGG 
CCCTTTGCGG AGAAAACGGG CATCTGCAAA ATCCGGCCAC CCAAGGATTG GCAACCTCCA 
TTTGCCTGTG AAGTAAAAAC CTTCCGTTTC ACTCCTAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CTAGAGTAAG ATTGGACTTC TTGGATCAAC TGGCAAAATT TTGGGAACTT 
CAAGGATCTA CATTGAAGAT CCCTGTGGTG GAGAGAAAAA TCCTGGATTT GTATGCTTTA 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATAGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GCCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CACTATGAAA GAATTCTCTA CCCATATGAA CTTTTCCAAT CTGGTGTCAG CCTTATGGGT 
GTACAAATGC CTGATTTAGA TCTTAAAGAA AAAGTTGAGG CTGAGGTTCT CAGCACTGAC 
ATCCAGCCTT CCCCAGAGCG GGGAACAAGA ATGAATATTC CACCAAAGAG AACAAGACGA 
GTTAAGTCTC AGTCAGACTC TGGAGAAGTA AATAGAAACA CAGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGACCCAA AGTTGTGGGC CTGGCAGTAG GAGCAAAAGA TAAAGAAGAT 
GAAGTCACCC GAAGAAGAAA AGTTACCAAC AGGTCAGATG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GAACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGCAT GTTTTGTGGT 
CGAGGAAATA ATGAGGATAA ACTGCTTTTG TGTGATGGGT GCGATGACAG CTATCATACA 
TTTTGTCTAC TTCCACCACT ACCTGATGTC CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTTGCTGAGG AATGTAACAA ACCTCGAGAA GCCTTTGGAT TTGAGCAAGC TGTAAGAGAA 
TATACACTTC AAAGCTTTGG AGAGATGGCA GATAATTTTA AATCTGATTA TTTCAATATG 
CCAGTCCATA TGGTTCCTAC AGAGCTAGTA GAAAAAGAAT TCTGGCGGCT AGTAAGTAGC 
ATTGAAGAAG ATGTTATTGT AGAGTATGGA GCTGATATCT CTTCAAAAGA TTTTGGAAGT 
GGATTTCCTA AAAAGGATGG TCAAAGAAAG ATGTTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTT CTGGAGCAGT CCGTTCTTGC ACATATTAAT 
GTGGACATTT CTGGTATGAA GGTGCCATGG CTCTATGTGG GAATGTGCTT TTCTTCTTTT 
TGCTGGCATA TTGAAGATCA CTGGAGTTAT TCCATTAACT ACTTGCATTG GGGCGAGCCA 
AAGACATGGT ATGGTGTACC ATCTCATGCT GCAGAACAAC TGGAGGAGGT GATGAGGGAG 
CTGGCCCCTG AGTTATTTGA ATCCCAGCCT GATCTCCTAC ATCAGTTAGT AACCATCATG 
AACCCAAATG TGCTCATGGA GCATGGTGTG CCTGTGTACA GGACTAATCA GTGTGCTGGA 
GAGTTTGTGG TGACGTTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG ATACAACTTT 
GCCGAAGCGG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA GTGTGTAAAT 
CACTATCGAC GGCTCAGGCG CCATTGTGTC TTTTCACATG AGGAACTCAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTATGCAA AGAGTTGACT 
CTCATGACTG AAGAAGAAAC ACGATTGAGA GAATCAGTTG TTCAAATGGG TGTCGTGATG 
TCAGAAGAAG AAGTCTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACTACATGTT TTCTCTCAGC TCTCACATGC TCCTGTAATC CGGAGCGACT TGTATGTCTG 
TATCATCCAA CTGATTTGTG CTCTTGCCCC ATGCAGAACA AATGTCTTAG GTACCGCTAT 
CCACTAGAAG ACCTTCCATC TCTGCTTTAT GGTGTCAAAG TGAGAGCACA ATCCTATGAC 
ACTTGGGTCA ATCGTGTTAC AGAAGCATTG TCAGCTAGCT TCAACCATAA GAAAGATTTG 
ATTGAATTGA GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAGC TCAGGGACGC GGTGAAAGAA GCTGAGACCT GTGGTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAAAA ACACAGGCAG AGCTCAGACC TGTTTCAAAA TAAGTGTACG 
TGTAAAAGAT TTTGGGGGAC TGAAGAGTTG GCTCCATGGT TAAGAGCACT GACTGTTCTT 
GCAGAGGTCC CAGGTTCAGT TCCCAGTACT CACATGGCTT CAGTTCAAGA GATCTATGTA 
TGCCCTTGCT CCTCCTTGAG CACCACACTC ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm5a ( NM_145997.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666109.2 Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), mRNA.

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CloneID	OMu13635
Clone ID Related Accession (Same CDS sequence)	NM_145997.2
Accession Version	NM_145997.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5073bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574611200000
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 5A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC155720.7 and AC078896.23. On or before Apr 19, 2009 this sequence version replaced XM_925213.3, XM_979596.2, XM_359326.6, NM_145997.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCG TGGGCCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC CGAGTGCCCG 
GTCTTTGAGC CCAGTTGGGA GGAGTTCACA GACCCGCTGA GTTTTATCGG GCGCATCCGG 
CCCTTTGCGG AGAAAACGGG CATCTGCAAA ATCCGGCCAC CCAAGGATTG GCAACCTCCA 
TTTGCCTGTG AAGTAAAAAC CTTCCGTTTC ACTCCTAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CTAGAGTAAG ATTGGACTTC TTGGATCAAC TGGCAAAATT TTGGGAACTT 
CAAGGATCTA CATTGAAGAT CCCTGTGGTG GAGAGAAAAA TCCTGGATTT GTATGCTTTA 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATAGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GCCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CACTATGAAA GAATTCTCTA CCCATATGAA CTTTTCCAAT CTGGTGTCAG CCTTATGGGT 
GTACAAATGC CTGATTTAGA TCTTAAAGAA AAAGTTGAGG CTGAGGTTCT CAGCACTGAC 
ATCCAGCCTT CCCCAGAGCG GGGAACAAGA ATGAATATTC CACCAAAGAG AACAAGACGA 
GTTAAGTCTC AGTCAGACTC TGGAGAAGTA AATAGAAACA CAGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGACCCAA AGTTGTGGGC CTGGCAGTAG GAGCAAAAGA TAAAGAAGAT 
GAAGTCACCC GAAGAAGAAA AGTTACCAAC AGGTCAGATG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GAACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGCAT GTTTTGTGGT 
CGAGGAAATA ATGAGGATAA ACTGCTTTTG TGTGATGGGT GCGATGACAG CTATCATACA 
TTTTGTCTAC TTCCACCACT ACCTGATGTC CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTTGCTGAGG AATGTAACAA ACCTCGAGAA GCCTTTGGAT TTGAGCAAGC TGTAAGAGAA 
TATACACTTC AAAGCTTTGG AGAGATGGCA GATAATTTTA AATCTGATTA TTTCAATATG 
CCAGTCCATA TGGTTCCTAC AGAGCTAGTA GAAAAAGAAT TCTGGCGGCT AGTAAGTAGC 
ATTGAAGAAG ATGTTATTGT AGAGTATGGA GCTGATATCT CTTCAAAAGA TTTTGGAAGT 
GGATTTCCTA AAAAGGATGG TCAAAGAAAG ATGTTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTT CTGGAGCAGT CCGTTCTTGC ACATATTAAT 
GTGGACATTT CTGGTATGAA GGTGCCATGG CTCTATGTGG GAATGTGCTT TTCTTCTTTT 
TGCTGGCATA TTGAAGATCA CTGGAGTTAT TCCATTAACT ACTTGCATTG GGGCGAGCCA 
AAGACATGGT ATGGTGTACC ATCTCATGCT GCAGAACAAC TGGAGGAGGT GATGAGGGAG 
CTGGCCCCTG AGTTATTTGA ATCCCAGCCT GATCTCCTAC ATCAGTTAGT AACCATCATG 
AACCCAAATG TGCTCATGGA GCATGGTGTG CCTGTGTACA GGACTAATCA GTGTGCTGGA 
GAGTTTGTGG TGACGTTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG ATACAACTTT 
GCCGAAGCGG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA GTGTGTAAAT 
CACTATCGAC GGCTCAGGCG CCATTGTGTC TTTTCACATG AGGAACTCAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTATGCAA AGAGTTGACT 
CTCATGACTG AAGAAGAAAC ACGATTGAGA GAATCAGTTG TTCAAATGGG TGTCGTGATG 
TCAGAAGAAG AAGTCTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACTACATGTT TTCTCTCAGC TCTCACATGC TCCTGTAATC CGGAGCGACT TGTATGTCTG 
TATCATCCAA CTGATTTGTG CTCTTGCCCC ATGCAGAACA AATGTCTTAG GTACCGCTAT 
CCACTAGAAG ACCTTCCATC TCTGCTTTAT GGTGTCAAAG TGAGAGCACA ATCCTATGAC 
ACTTGGGTCA ATCGTGTTAC AGAAGCATTG TCAGCTAGCT TCAACCATAA GAAAGATTTG 
ATTGAATTGA GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAGC TCAGGGACGC GGTGAAAGAA GCTGAGACCT GTGGTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAAAA ACACAGGCAG AGCTCAGATA GTGGGAAGAC TCGGACCAAA 
CTGACAGTAG AAGAATTGAA GGCCTTTGTC CAACAACTTG TTAGTCTTCC GTGTGTCATC 
AGCCAAACTC GACAAGTAAA GAATCTGCTG GATGATGTAG AAGAATTTCA TGAACGTGCC 
CAGGAGGCCA TGATGGATGA AACCCCAGAT TCTTCCAAAC TCCAAATGTT AATAGACATG 
GGCTCTAGTC TCTATGTGGA GCTACCTGAA TTGCCCCGAC TAAAGCAAGA GCTCCAGCAG 
GCTCGATGGC TGGATGAAGT AAGGCTAACT CTATCAGATC CACAACAAGT CACTTTGGAT 
GTCATGAAGA AATTGATTGA CTCTGGCGTA GGCTTGGCAC CTCACCATGC TGTAGAAAAA 
GCAATGGCCG AACTACAGGA ACTCCTTACA GTCTCTGAAC GATGGGAAGA GAAGGCTAAG 
GTCTGCCTGC AAGCAAGACC TCGGCACAGT ATGGCAAATT TAGAAAATAT TGTGAATGAA 
GCCAAGAACA TTCCAGCCTT TCTACCCAAT GTGTTGTCCT TAAAAGAAGC CTTACAAAAG 
GCTCGTGAAT GGACAGCTAA AGTGGAAGCT ATTCAGAGTG GCAACAACTA TGCTTACTTG 
GAACAGCTTG AGAGCCTATC TGCTAAAGGA CGCCCTATCC CTGTGCGTCT TGATGCCTTG 
CCTCAAGTGG AGTCACAGGT AGCAGCAGCA CGGGCCTGGA GAGAACGTAC TGGGCGGACC 
TTCCTTAAAA AGAATTCCAG CCATACATTG TTACAGGTGC TAAGTCCACG AACTGACATT 
GGTGTATATG GGAGTGGTAA AAACAGGAGG AAAAAGGTAA AAGAAATAAT AGAAAAAGAA 
AAGGAGAAGG ACCTCGACCT TGAGCCTTTG AGTGACTTAG AGGAAGGACT GGAGGAGTCA 
AGAGATACAG CCATGGTGGT GGCAGTTTTC AAAGAACGAG AGCAAAAGGA GATTGAAGCC 
ATGCATTCCC TCAGAGCAGC CAACCTAGCC AAGATGACAA TTGTGGAGCG CATAGAAGAA 
GTGAAATTTT GTATTTGCCG CAAGACAGCC AGTGGGTTTA TGCTACAGTG TGAGCTCTGC 
AAAGACTGGT TCCATAACAG CTGTGTTCCC CTTCCTAAAT CAAGTTCCCA GAAAAAGGGA 
TCCAGCTGGC AGGCTAAAGA TGTAAAATTC CTTTGCCCTC TTTGCATGAG ATCTCGGAGG 
CCAAGGCTAG AGACTATTCT GTCACTCCTG GTATCCCTTC AGAAGTTGCC TGTACGGTTG 
CCGGAAGGAG AAGCACTGCA GTGTTTGACA GAACGTGCCA TGAGTTGGCA AGATAAAGCA 
CGCCAAGCTT TAGCCACAGA TGAACTGTCC TCTGCCCTGG CCAAGCTCTC TGTGCTAAGC 
CAGCGTATGG TGGAACAAGC AGCTAGAGAA AAAACTGAAA AGATTATCAG TGCAGAACTC 
CAAAAAGCAG CTGCCAATCC AGATTTACAG GGACACTTAC CTAGTTTCCA GCAGTCTGCT 
TTTAACCGGG TGGTGAGCAG TGTATCATCT TCCCCCCACC AAACAATGGA CTATGATGAT 
GAAGAAACAG ATTCTGATGA AGATATTCGG GAGACATACG GCTATGACAT GAAGGATACA 
GCCAGCGTGA AGTCCTCTAG TAGTCTGGAA CCCAATCTCT TTTGTGATGA AGAGATTCCC 
ATCAAGTCTG AGGAAGTGGT GACTCACATG TGGACGGCAC CGTCATTCTG TGCAGAGCAT 
GCATATTCTT CTGCTTCAAA GAGTTGTTCT CAAGGTTCTA GCACTCCAAG AAAGCAGCCT 
CGGAAGAGCC CTTTGGTTCC CAGAAGTTTG GAGCCTCCAG TATTGGAATT GTCTCCTGGA 
GCAAAAGCCC AGTTGGAAGA ACTCATGATG GTTGGAGACC TCCTAGAAGT GTCTCTGGAT 
GAGACACAAC ACATTTGGCG GATTTTGCAG GCCACACATC CACCCTCAGA GGACAGATTC 
TTACATATCA TGGAGGATGA TAGCATAGAA GAGAAACCAT TAAAAATGAA AGGAAAGGAC 
TCTTCAGAGA AGAAACGGAA ACGGAAGCTA GAAAAGGTAG AACAGCTTTT TGGAGAAGGA 
AAACAGAAGA CCAAGGAGCT AAAGAAAATA GATAAACCTA AAAAGAAGAA ATTAAAATTA 
AATGTGGACA AATCAAAAGA GCTGAATAAA TTGGCCAAGA AGTTAGCTAA AGAAGAAGAG 
CGAAAGAAAA AGAAAGAAAA GGCTGCTGCC GCCAAAGTGG AGCTTGTGAA AGAGAGCACG 
GAGAAGAAAC GGGAGAGGAA GGTGTTGGAT ATCCCCTCAA AGTATGACTG GTCGGGGGCA 
GAGGAGTCTG ATGATGAGAA TGCTGTGTGT GCAGCCCAAA ACTGCCAAAG GCCGTGTAAG 
GACAAGGTAG ACTGGGTACA GTGTGATGGT GGCTGTGATG AGTGGTTTCA TCAAGTTTGT 
GTTGGTGTAT CCGCAGAAAT GGCTGAAAAT GAAGATTACA TCTGTATAAA CTGTGCAAAG 
AAGCAGGGGC CAGATAGCCC AGGCCAAGCA CCACCTCCTC CCTTCCTAAT GAGCTACAAA 
CTACCAATGG AGGATCTTAA AGAGACCAGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_666109.2
CDS	516..5588
Translation	MASVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPFAEKTGICKIRPPKDWQPPFACEVKTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPPKRTRRVKSQSDSGEVNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPKKDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCSCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALSASFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDSGKTRTKLTVEELKAFVQQLVSLPCVISQTRQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRHSMANLENIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGNNYAYLEQLESLSAKGRPIPVRLDALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKEIIEKEKEKDLDLEPLSDLEEGLEESRDTAMVVAVFKEREQKEIEAMHSLRAANLAKMTIVERIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKGSSWQAKDVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDKARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPHQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQPRKSPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSIEEKPLKMKGKDSSEKKRKRKLEKVEQLFGEGKQKTKELKKIDKPKKKKLKLNVDKSKELNKLAKKLAKEEERKKKKEKAAAAKVELVKESTEKKRERKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVSAEMAENEDYICINCAKKQGPDSPGQAPPPPFLMSYKLPMEDLKETS

Target ORF information:

RefSeq Version	NM_145997.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus lysine (K)-specific demethylase 5A (Kdm5a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145997.2

ORF Insert Sequence:

ATGGCGTCCG TGGGCCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC CGAGTGCCCG 
GTCTTTGAGC CCAGTTGGGA GGAGTTCACA GACCCGCTGA GTTTTATCGG GCGCATCCGG 
CCCTTTGCGG AGAAAACGGG CATCTGCAAA ATCCGGCCAC CCAAGGATTG GCAACCTCCA 
TTTGCCTGTG AAGTAAAAAC CTTCCGTTTC ACTCCTAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CTAGAGTAAG ATTGGACTTC TTGGATCAAC TGGCAAAATT TTGGGAACTT 
CAAGGATCTA CATTGAAGAT CCCTGTGGTG GAGAGAAAAA TCCTGGATTT GTATGCTTTA 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATAGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GCCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CACTATGAAA GAATTCTCTA CCCATATGAA CTTTTCCAAT CTGGTGTCAG CCTTATGGGT 
GTACAAATGC CTGATTTAGA TCTTAAAGAA AAAGTTGAGG CTGAGGTTCT CAGCACTGAC 
ATCCAGCCTT CCCCAGAGCG GGGAACAAGA ATGAATATTC CACCAAAGAG AACAAGACGA 
GTTAAGTCTC AGTCAGACTC TGGAGAAGTA AATAGAAACA CAGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGACCCAA AGTTGTGGGC CTGGCAGTAG GAGCAAAAGA TAAAGAAGAT 
GAAGTCACCC GAAGAAGAAA AGTTACCAAC AGGTCAGATG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GAACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGCAT GTTTTGTGGT 
CGAGGAAATA ATGAGGATAA ACTGCTTTTG TGTGATGGGT GCGATGACAG CTATCATACA 
TTTTGTCTAC TTCCACCACT ACCTGATGTC CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTTGCTGAGG AATGTAACAA ACCTCGAGAA GCCTTTGGAT TTGAGCAAGC TGTAAGAGAA 
TATACACTTC AAAGCTTTGG AGAGATGGCA GATAATTTTA AATCTGATTA TTTCAATATG 
CCAGTCCATA TGGTTCCTAC AGAGCTAGTA GAAAAAGAAT TCTGGCGGCT AGTAAGTAGC 
ATTGAAGAAG ATGTTATTGT AGAGTATGGA GCTGATATCT CTTCAAAAGA TTTTGGAAGT 
GGATTTCCTA AAAAGGATGG TCAAAGAAAG ATGTTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTT CTGGAGCAGT CCGTTCTTGC ACATATTAAT 
GTGGACATTT CTGGTATGAA GGTGCCATGG CTCTATGTGG GAATGTGCTT TTCTTCTTTT 
TGCTGGCATA TTGAAGATCA CTGGAGTTAT TCCATTAACT ACTTGCATTG GGGCGAGCCA 
AAGACATGGT ATGGTGTACC ATCTCATGCT GCAGAACAAC TGGAGGAGGT GATGAGGGAG 
CTGGCCCCTG AGTTATTTGA ATCCCAGCCT GATCTCCTAC ATCAGTTAGT AACCATCATG 
AACCCAAATG TGCTCATGGA GCATGGTGTG CCTGTGTACA GGACTAATCA GTGTGCTGGA 
GAGTTTGTGG TGACGTTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG ATACAACTTT 
GCCGAAGCGG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA GTGTGTAAAT 
CACTATCGAC GGCTCAGGCG CCATTGTGTC TTTTCACATG AGGAACTCAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTATGCAA AGAGTTGACT 
CTCATGACTG AAGAAGAAAC ACGATTGAGA GAATCAGTTG TTCAAATGGG TGTCGTGATG 
TCAGAAGAAG AAGTCTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACTACATGTT TTCTCTCAGC TCTCACATGC TCCTGTAATC CGGAGCGACT TGTATGTCTG 
TATCATCCAA CTGATTTGTG CTCTTGCCCC ATGCAGAACA AATGTCTTAG GTACCGCTAT 
CCACTAGAAG ACCTTCCATC TCTGCTTTAT GGTGTCAAAG TGAGAGCACA ATCCTATGAC 
ACTTGGGTCA ATCGTGTTAC AGAAGCATTG TCAGCTAGCT TCAACCATAA GAAAGATTTG 
ATTGAATTGA GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAGC TCAGGGACGC GGTGAAAGAA GCTGAGACCT GTGGTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAAAA ACACAGGCAG AGCTCAGATA GTGGGAAGAC TCGGACCAAA 
CTGACAGTAG AAGAATTGAA GGCCTTTGTC CAACAACTTG TTAGTCTTCC GTGTGTCATC 
AGCCAAACTC GACAAGTAAA GAATCTGCTG GATGATGTAG AAGAATTTCA TGAACGTGCC 
CAGGAGGCCA TGATGGATGA AACCCCAGAT TCTTCCAAAC TCCAAATGTT AATAGACATG 
GGCTCTAGTC TCTATGTGGA GCTACCTGAA TTGCCCCGAC TAAAGCAAGA GCTCCAGCAG 
GCTCGATGGC TGGATGAAGT AAGGCTAACT CTATCAGATC CACAACAAGT CACTTTGGAT 
GTCATGAAGA AATTGATTGA CTCTGGCGTA GGCTTGGCAC CTCACCATGC TGTAGAAAAA 
GCAATGGCCG AACTACAGGA ACTCCTTACA GTCTCTGAAC GATGGGAAGA GAAGGCTAAG 
GTCTGCCTGC AAGCAAGACC TCGGCACAGT ATGGCAAATT TAGAAAATAT TGTGAATGAA 
GCCAAGAACA TTCCAGCCTT TCTACCCAAT GTGTTGTCCT TAAAAGAAGC CTTACAAAAG 
GCTCGTGAAT GGACAGCTAA AGTGGAAGCT ATTCAGAGTG GCAACAACTA TGCTTACTTG 
GAACAGCTTG AGAGCCTATC TGCTAAAGGA CGCCCTATCC CTGTGCGTCT TGATGCCTTG 
CCTCAAGTGG AGTCACAGGT AGCAGCAGCA CGGGCCTGGA GAGAACGTAC TGGGCGGACC 
TTCCTTAAAA AGAATTCCAG CCATACATTG TTACAGGTGC TAAGTCCACG AACTGACATT 
GGTGTATATG GGAGTGGTAA AAACAGGAGG AAAAAGGTAA AAGAAATAAT AGAAAAAGAA 
AAGGAGAAGG ACCTCGACCT TGAGCCTTTG AGTGACTTAG AGGAAGGACT GGAGGAGTCA 
AGAGATACAG CCATGGTGGT GGCAGTTTTC AAAGAACGAG AGCAAAAGGA GATTGAAGCC 
ATGCATTCCC TCAGAGCAGC CAACCTAGCC AAGATGACAA TTGTGGAGCG CATAGAAGAA 
GTGAAATTTT GTATTTGCCG CAAGACAGCC AGTGGGTTTA TGCTACAGTG TGAGCTCTGC 
AAAGACTGGT TCCATAACAG CTGTGTTCCC CTTCCTAAAT CAAGTTCCCA GAAAAAGGGA 
TCCAGCTGGC AGGCTAAAGA TGTAAAATTC CTTTGCCCTC TTTGCATGAG ATCTCGGAGG 
CCAAGGCTAG AGACTATTCT GTCACTCCTG GTATCCCTTC AGAAGTTGCC TGTACGGTTG 
CCGGAAGGAG AAGCACTGCA GTGTTTGACA GAACGTGCCA TGAGTTGGCA AGATAAAGCA 
CGCCAAGCTT TAGCCACAGA TGAACTGTCC TCTGCCCTGG CCAAGCTCTC TGTGCTAAGC 
CAGCGTATGG TGGAACAAGC AGCTAGAGAA AAAACTGAAA AGATTATCAG TGCAGAACTC 
CAAAAAGCAG CTGCCAATCC AGATTTACAG GGACACTTAC CTAGTTTCCA GCAGTCTGCT 
TTTAACCGGG TGGTGAGCAG TGTATCATCT TCCCCCCACC AAACAATGGA CTATGATGAT 
GAAGAAACAG ATTCTGATGA AGATATTCGG GAGACATACG GCTATGACAT GAAGGATACA 
GCCAGCGTGA AGTCCTCTAG TAGTCTGGAA CCCAATCTCT TTTGTGATGA AGAGATTCCC 
ATCAAGTCTG AGGAAGTGGT GACTCACATG TGGACGGCAC CGTCATTCTG TGCAGAGCAT 
GCATATTCTT CTGCTTCAAA GAGTTGTTCT CAAGGTTCTA GCACTCCAAG AAAGCAGCCT 
CGGAAGAGCC CTTTGGTTCC CAGAAGTTTG GAGCCTCCAG TATTGGAATT GTCTCCTGGA 
GCAAAAGCCC AGTTGGAAGA ACTCATGATG GTTGGAGACC TCCTAGAAGT GTCTCTGGAT 
GAGACACAAC ACATTTGGCG GATTTTGCAG GCCACACATC CACCCTCAGA GGACAGATTC 
TTACATATCA TGGAGGATGA TAGCATAGAA GAGAAACCAT TAAAAATGAA AGGAAAGGAC 
TCTTCAGAGA AGAAACGGAA ACGGAAGCTA GAAAAGGTAG AACAGCTTTT TGGAGAAGGA 
AAACAGAAGA CCAAGGAGCT AAAGAAAATA GATAAACCTA AAAAGAAGAA ATTAAAATTA 
AATGTGGACA AATCAAAAGA GCTGAATAAA TTGGCCAAGA AGTTAGCTAA AGAAGAAGAG 
CGAAAGAAAA AGAAAGAAAA GGCTGCTGCC GCCAAAGTGG AGCTTGTGAA AGAGAGCACG 
GAGAAGAAAC GGGAGAGGAA GGTGTTGGAT ATCCCCTCAA AGTATGACTG GTCGGGGGCA 
GAGGAGTCTG ATGATGAGAA TGCTGTGTGT GCAGCCCAAA ACTGCCAAAG GCCGTGTAAG 
GACAAGGTAG ACTGGGTACA GTGTGATGGT GGCTGTGATG AGTGGTTTCA TCAAGTTTGT 
GTTGGTGTAT CCGCAGAAAT GGCTGAAAAT GAAGATTACA TCTGTATAAA CTGTGCAAAG 
AAGCAGGGGC CAGATAGCCC AGGCCAAGCA CCACCTCCTC CCTTCCTAAT GAGCTACAAA 
CTACCAATGG AGGATCTTAA AGAGACCAGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner.
Nucleic acids research47(9)4521-4538(2019 05)
Dreval K,Lake RJ,Fan HY

Autochthonous tumors driven by
Proceedings of the National Academy of Sciences of the United States of America115(16)E3741-E3748(2018 04)
McBrayer SK,Olenchock BA,DiNatale GJ,Shi DD,Khanal J,Jennings RB,Novak JS,Oser MG,Robbins AK,Modiste R,Bonal D,Moslehi J,Bronson RT,Neuberg D,Nguyen QD,Signoretti S,Losman JA,Kaelin WG Jr

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.
Frontiers in neuroscience12571(2018)
Elsen GE,Bedogni F,Hodge RD,Bammler TK,MacDonald JW,Lindtner S,Rubenstein JLR,Hevner RF

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Nature537(7621)548-552(2016 09)
Dahl JA,Jung I,Aanes H,Greggains GD,Manaf A,Lerdrup M,Li G,Kuan S,Li B,Lee AY,Preissl S,Jermstad I,Haugen MH,Suganthan R,Bjørås M,Hansen K,Dalen KT,Fedorcsak P,Ren B,Klungland A

KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis.
Cell death & disease7(8)e2335(2016 08)
Wang C,Wang J,Li J,Hu G,Shan S,Li Q,Zhang X

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Kdm5a cDNA ORF clone, Mus musculus(house mouse)

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