Stxbp1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stxbp1
Entrez Gene ID	20910
Full Name	syntaxin binding protein 1
Synonyms	AI317162,AI326233,MMS10-G,Ms10g,Munc-18a,Munc18-1,N-sec1,Rb-sec1,Sxtbp1,Unc18-1,Unc18h,nsec1
General protein information	Preferred Names syntaxin binding protein 1 Names syntaxin-binding protein 1 UNC-18 homolog minisatellite 10g detected by probe MMS10 protein unc-18 homolog 1 protein unc-18 homolog A unc-18-1 unc-18A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 B\|2 22.09 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001113569.1	NP_001107041.1	syntaxin-binding protein 1 isoform a
NM_009295.2	NP_033321.2	syntaxin-binding protein 1 isoform b

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	STXBP1	XP_001095617.2
Mus musculus (house mouse)	Stxbp1	NP_033321.2
Drosophila melanogaster (fruit fly)	Rop	NP_001261404.1
Caenorhabditis elegans (roundworm)	unc-18	NP_001024606.1
Canis lupus familiaris (dog)	STXBP1	XP_851554.2
Danio rerio (zebrafish)	stxbp1a	NP_001020353.1
Oryza sativa (rice)	Os04g0252400	NP_001052319.2
Xenopus tropicalis (tropical clawed frog)	stxbp1	NP_001072521.1
Homo sapiens (human)	STXBP1	NP_001027392.1
Bos taurus (cattle)	STXBP1	NP_777044.1
Gallus gallus (chicken)	STXBP1	XP_004945852.1
Arabidopsis thaliana (thale cress)	SEC1A	NP_001184888.1
Arabidopsis thaliana (thale cress)	SEC1B	NP_567388.1
Pan troglodytes (chimpanzee)	STXBP1	XP_003312377.1
Rattus norvegicus (Norway rat)	Stxbp1	NP_037170.1
Arabidopsis thaliana (thale cress)	KEU	NP_563905.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003023	XP_311854.4

Gene Ontology
Bibliography

Related articles in PubMed

Impaired cortico-striatal excitatory transmission triggers epilepsy.
Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, Yamakawa K
Nature communications10(1)1917(2019 04)

Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.
Jaramillo AM, Piccotti L, Velasco WV, Delgado ASH, Azzegagh Z, Chung F, Nazeer U, Farooq J, Brenner J, Parker-Thornburg J, Scott BL, Evans CM, Adachi R, Burns AR, Kreda SM, Tuvim MJ, Dickey BF
JCI insight4(6)(2019 Mar)

Syntaxin clusters at secretory granules in a munc18-bound conformation.
Yin P, Gandasi NR, Arora S, Omar-Hmeadi M, Saras J, Barg S
Molecular biology of the cell29(22)2700-2708(2018 11)

Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
Guiberson NGL, Pineda A, Abramov D, Kharel P, Carnazza KE, Wragg RT, Dittman JS, Burré J
Nature communications9(1)3986(2018 09)

Differential gene regulatory plasticity between upper and lower layer cortical excitatory neurons.
Yang L, Chen L, Cai C, Li H
Molecular and cellular neurosciences9022-32(2018 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Stxbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stxbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21306	NM_009295.2 Latest version!	Mus musculus syntaxin binding protein 1 (Stxbp1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu21308	NM_001113569.1 Latest version!	Mus musculus syntaxin binding protein 1 (Stxbp1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$349.30 $499.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stxbp1 ( NM_009295.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033321.2 Mus musculus syntaxin binding protein 1 (Stxbp1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu21306
Clone ID Related Accession (Same CDS sequence)	NM_009295.2
Accession Version	NM_009295.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1785bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573401600000
Organism	Mus musculus(house mouse)
Product	syntaxin-binding protein 1 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB852672.1, AF326563.1, BC031728.1 and AK004780.1. On Jan 19, 2008 this sequence version replaced NM_009295.1. Transcript Variant: This variant (2) lacks an alternate exon in the coding region, (compared to variant 1), which results in a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.15833.1, SRR1660821.112372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCCCA TTGGCCTCAA GGCGGTGGTC GGAGAGAAGA TCATGCATGA TGTGATCAAG 
AAGGTGAAGA AGAAGGGCGA GTGGAAGGTG CTGGTGGTGG ACCAGTTAAG CATGAGGATG 
CTGTCCTCCT GCTGCAAGAT GACAGACATC ATGACCGAGG GCATCACAAT TGTGGAGGAT 
ATCAACAAGC GCCGAGAGCC ACTCCCCAGC CTGGAGGCCG TGTACCTCAT CACCCCATCT 
GAGAAGTCTG TCCACTCTCT GATCAGTGAT TTTAAGGACC CGCCGACTGC TAAATATCGG 
GCTGCGCATG TGTTCTTCAC AGACTCGTGT CCAGATGCCC TATTTAACGA GCTGGTAAAA 
TCCCGAGCAG CCAAAGTCAT CAAGACGCTG ACGGAAATCA ACATTGCGTT TCTCCCCTAT 
GAGTCCCAGG TGTATTCCCT GGACTCCGCT GACTCTTTCC AAAGCTTCTA CAGCCCTCAC 
AAGGCGCAGA TGAAGAATCC GATACTGGAA CGCCTGGCAG AGCAGATCGC AACCCTGTGT 
GCCACCCTGA AGGAGTATCC AGCTGTGCGG TATCGGGGGG AGTACAAGGA CAATGCCTTG 
CTGGCTCAGC TGATCCAGGA CAAGCTGGAT GCCTATAAAG CCGACGATCC AACAATGGGG 
GAGGGTCCCG ACAAGGCACG GTCCCAGCTC CTGATCCTGG ATCGTGGCTT TGACCCCAGC 
TCCCCTGTGC TCCATGAACT GACATTCCAG GCTATGAGTT ATGACCTGCT GCCTATCGAA 
AATGATGTTT ACAAGTATGA GACCAGCGGC ATTGGAGAGG CGCGGGTGAA GGAGGTGCTA 
CTGGATGAGG ACGATGACCT GTGGATTGCG CTGCGACACA AGCACATCGC AGAGGTGTCC 
CAGGAAGTCA CCCGGTCTCT GAAGGACTTT TCCTCTAGCA AGAGGATGAA CACTGGCGAG 
AAGACCACCA TGCGGGACCT GTCCCAGATG CTGAAGAAAA TGCCCCAGTA CCAGAAGGAG 
CTCAGCAAGT ATTCGACTCA CCTGCACCTT GCTGAAGACT GCATGAAGCA TTACCAAGGC 
ACTGTAGACA AACTCTGCCG CGTGGAGCAG GACCTGGCAA TGGGCACAGA TGCTGAGGGG 
GAAAAAATCA AGGACCCCAT GAGAGCCATT GTCCCCATCC TGCTGGATGC GAACGTCAGC 
ACTTACGACA AAATCCGTAT CATCCTTCTC TACATCTTCC TGAAGAACGG TATCACTGAG 
GAGAACCTAA ACAAACTCAT CCAGCACGCT CAGATACCCC CAGAGGACAG CGAGATCATC 
ACCAACATGG CTCACCTCGG CGTGCCCATC GTCACGGATT CCACACTACG CCGCCGAAGC 
AAACCGGAGC GGAAGGAGCG TATCAGTGAG CAGACCTACC AGCTCTCACG ATGGACCCCG 
ATCATTAAAG ACATTATGGA GGACACTATC GAAGACAAGC TGGATACAAA GCACTACCCA 
TACATCTCTA CCCGCTCGTC CGCGTCCTTC AGCACCACTG CTGTGAGTGC CCGCTATGGA 
CATTGGCACA AGAATAAGGC CCCCGGGGAG TACCGCAGCG GTCCCCGCCT CATTATTTTC 
ATCCTTGGGG GTGTGAGCCT GAATGAGATG CGCTGTGCTT ACGAAGTGAC CCAGGCCAAC 
GGCAAGTGGG AAGTGCTGAT AGGATCCACG CACATTCTCA CCCCACAGAA ACTGCTGGAC 
ACGCTGAAGA AGCTGAATAA AACAGATGAA GAAATAAGCA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033321.2
CDS	142..1926
Translation	MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS

Target ORF information:

RefSeq Version	NM_009295.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin binding protein 1 (Stxbp1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009295.2

ORF Insert Sequence:

ATGGCCCCCA TTGGCCTCAA GGCGGTGGTC GGAGAGAAGA TCATGCATGA TGTGATCAAG 
AAGGTGAAGA AGAAGGGCGA GTGGAAGGTG CTGGTGGTGG ACCAGTTAAG CATGAGGATG 
CTGTCCTCCT GCTGCAAGAT GACAGACATC ATGACCGAGG GCATCACAAT TGTGGAGGAT 
ATCAACAAGC GCCGAGAGCC ACTCCCCAGC CTGGAGGCCG TGTACCTCAT CACCCCATCT 
GAGAAGTCTG TCCACTCTCT GATCAGTGAT TTTAAGGACC CGCCGACTGC TAAATATCGG 
GCTGCGCATG TGTTCTTCAC AGACTCGTGT CCAGATGCCC TATTTAACGA GCTGGTAAAA 
TCCCGAGCAG CCAAAGTCAT CAAGACGCTG ACGGAAATCA ACATTGCGTT TCTCCCCTAT 
GAGTCCCAGG TGTATTCCCT GGACTCCGCT GACTCTTTCC AAAGCTTCTA CAGCCCTCAC 
AAGGCGCAGA TGAAGAATCC GATACTGGAA CGCCTGGCAG AGCAGATCGC AACCCTGTGT 
GCCACCCTGA AGGAGTATCC AGCTGTGCGG TATCGGGGGG AGTACAAGGA CAATGCCTTG 
CTGGCTCAGC TGATCCAGGA CAAGCTGGAT GCCTATAAAG CCGACGATCC AACAATGGGG 
GAGGGTCCCG ACAAGGCACG GTCCCAGCTC CTGATCCTGG ATCGTGGCTT TGACCCCAGC 
TCCCCTGTGC TCCATGAACT GACATTCCAG GCTATGAGTT ATGACCTGCT GCCTATCGAA 
AATGATGTTT ACAAGTATGA GACCAGCGGC ATTGGAGAGG CGCGGGTGAA GGAGGTGCTA 
CTGGATGAGG ACGATGACCT GTGGATTGCG CTGCGACACA AGCACATCGC AGAGGTGTCC 
CAGGAAGTCA CCCGGTCTCT GAAGGACTTT TCCTCTAGCA AGAGGATGAA CACTGGCGAG 
AAGACCACCA TGCGGGACCT GTCCCAGATG CTGAAGAAAA TGCCCCAGTA CCAGAAGGAG 
CTCAGCAAGT ATTCGACTCA CCTGCACCTT GCTGAAGACT GCATGAAGCA TTACCAAGGC 
ACTGTAGACA AACTCTGCCG CGTGGAGCAG GACCTGGCAA TGGGCACAGA TGCTGAGGGG 
GAAAAAATCA AGGACCCCAT GAGAGCCATT GTCCCCATCC TGCTGGATGC GAACGTCAGC 
ACTTACGACA AAATCCGTAT CATCCTTCTC TACATCTTCC TGAAGAACGG TATCACTGAG 
GAGAACCTAA ACAAACTCAT CCAGCACGCT CAGATACCCC CAGAGGACAG CGAGATCATC 
ACCAACATGG CTCACCTCGG CGTGCCCATC GTCACGGATT CCACACTACG CCGCCGAAGC 
AAACCGGAGC GGAAGGAGCG TATCAGTGAG CAGACCTACC AGCTCTCACG ATGGACCCCG 
ATCATTAAAG ACATTATGGA GGACACTATC GAAGACAAGC TGGATACAAA GCACTACCCA 
TACATCTCTA CCCGCTCGTC CGCGTCCTTC AGCACCACTG CTGTGAGTGC CCGCTATGGA 
CATTGGCACA AGAATAAGGC CCCCGGGGAG TACCGCAGCG GTCCCCGCCT CATTATTTTC 
ATCCTTGGGG GTGTGAGCCT GAATGAGATG CGCTGTGCTT ACGAAGTGAC CCAGGCCAAC 
GGCAAGTGGG AAGTGCTGAT AGGATCCACG CACATTCTCA CCCCACAGAA ACTGCTGGAC 
ACGCTGAAGA AGCTGAATAA AACAGATGAA GAAATAAGCA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stxbp1 ( NM_001113569.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001107041.1 Mus musculus syntaxin binding protein 1 (Stxbp1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu21308
Clone ID Related Accession (Same CDS sequence)	NM_001113569.1
Accession Version	NM_001113569.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1812bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573401600000
Organism	Mus musculus(house mouse)
Product	syntaxin-binding protein 1 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB852672.1, BC031728.1 and AK004780.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.168300.1, SRR1660819.107105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGCCCCCA TTGGCCTCAA GGCGGTGGTC GGAGAGAAGA TCATGCATGA TGTGATCAAG 
AAGGTGAAGA AGAAGGGCGA GTGGAAGGTG CTGGTGGTGG ACCAGTTAAG CATGAGGATG 
CTGTCCTCCT GCTGCAAGAT GACAGACATC ATGACCGAGG GCATCACAAT TGTGGAGGAT 
ATCAACAAGC GCCGAGAGCC ACTCCCCAGC CTGGAGGCCG TGTACCTCAT CACCCCATCT 
GAGAAGTCTG TCCACTCTCT GATCAGTGAT TTTAAGGACC CGCCGACTGC TAAATATCGG 
GCTGCGCATG TGTTCTTCAC AGACTCGTGT CCAGATGCCC TATTTAACGA GCTGGTAAAA 
TCCCGAGCAG CCAAAGTCAT CAAGACGCTG ACGGAAATCA ACATTGCGTT TCTCCCCTAT 
GAGTCCCAGG TGTATTCCCT GGACTCCGCT GACTCTTTCC AAAGCTTCTA CAGCCCTCAC 
AAGGCGCAGA TGAAGAATCC GATACTGGAA CGCCTGGCAG AGCAGATCGC AACCCTGTGT 
GCCACCCTGA AGGAGTATCC AGCTGTGCGG TATCGGGGGG AGTACAAGGA CAATGCCTTG 
CTGGCTCAGC TGATCCAGGA CAAGCTGGAT GCCTATAAAG CCGACGATCC AACAATGGGG 
GAGGGTCCCG ACAAGGCACG GTCCCAGCTC CTGATCCTGG ATCGTGGCTT TGACCCCAGC 
TCCCCTGTGC TCCATGAACT GACATTCCAG GCTATGAGTT ATGACCTGCT GCCTATCGAA 
AATGATGTTT ACAAGTATGA GACCAGCGGC ATTGGAGAGG CGCGGGTGAA GGAGGTGCTA 
CTGGATGAGG ACGATGACCT GTGGATTGCG CTGCGACACA AGCACATCGC AGAGGTGTCC 
CAGGAAGTCA CCCGGTCTCT GAAGGACTTT TCCTCTAGCA AGAGGATGAA CACTGGCGAG 
AAGACCACCA TGCGGGACCT GTCCCAGATG CTGAAGAAAA TGCCCCAGTA CCAGAAGGAG 
CTCAGCAAGT ATTCGACTCA CCTGCACCTT GCTGAAGACT GCATGAAGCA TTACCAAGGC 
ACTGTAGACA AACTCTGCCG CGTGGAGCAG GACCTGGCAA TGGGCACAGA TGCTGAGGGG 
GAAAAAATCA AGGACCCCAT GAGAGCCATT GTCCCCATCC TGCTGGATGC GAACGTCAGC 
ACTTACGACA AAATCCGTAT CATCCTTCTC TACATCTTCC TGAAGAACGG TATCACTGAG 
GAGAACCTAA ACAAACTCAT CCAGCACGCT CAGATACCCC CAGAGGACAG CGAGATCATC 
ACCAACATGG CTCACCTCGG CGTGCCCATC GTCACGGATT CCACACTACG CCGCCGAAGC 
AAACCGGAGC GGAAGGAGCG TATCAGTGAG CAGACCTACC AGCTCTCACG ATGGACCCCG 
ATCATTAAAG ACATTATGGA GGACACTATC GAAGACAAGC TGGATACAAA GCACTACCCA 
TACATCTCTA CCCGCTCGTC CGCGTCCTTC AGCACCACTG CTGTGAGTGC CCGCTATGGA 
CATTGGCACA AGAATAAGGC CCCCGGGGAG TACCGCAGCG GTCCCCGCCT CATTATTTTC 
ATCCTTGGGG GTGTGAGCCT GAATGAGATG CGCTGTGCTT ACGAAGTGAC CCAGGCCAAC 
GGCAAGTGGG AAGTGCTGAT AGGTTCTACT CACATTCTCA CTCCCACCAA ATTCCTCATG 
GACCTGAGAC ACCCCGACTT CAGGGAGTCC TCTAGGGTAT CTTTTGAGGA TCAGGCTCCA 
ACAATGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001107041.1
CDS	147..1958
Translation	MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAPTME

Target ORF information:

RefSeq Version	NM_001113569.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syntaxin binding protein 1 (Stxbp1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001113569.1

ORF Insert Sequence:

ATGGCCCCCA TTGGCCTCAA GGCGGTGGTC GGAGAGAAGA TCATGCATGA TGTGATCAAG 
AAGGTGAAGA AGAAGGGCGA GTGGAAGGTG CTGGTGGTGG ACCAGTTAAG CATGAGGATG 
CTGTCCTCCT GCTGCAAGAT GACAGACATC ATGACCGAGG GCATCACAAT TGTGGAGGAT 
ATCAACAAGC GCCGAGAGCC ACTCCCCAGC CTGGAGGCCG TGTACCTCAT CACCCCATCT 
GAGAAGTCTG TCCACTCTCT GATCAGTGAT TTTAAGGACC CGCCGACTGC TAAATATCGG 
GCTGCGCATG TGTTCTTCAC AGACTCGTGT CCAGATGCCC TATTTAACGA GCTGGTAAAA 
TCCCGAGCAG CCAAAGTCAT CAAGACGCTG ACGGAAATCA ACATTGCGTT TCTCCCCTAT 
GAGTCCCAGG TGTATTCCCT GGACTCCGCT GACTCTTTCC AAAGCTTCTA CAGCCCTCAC 
AAGGCGCAGA TGAAGAATCC GATACTGGAA CGCCTGGCAG AGCAGATCGC AACCCTGTGT 
GCCACCCTGA AGGAGTATCC AGCTGTGCGG TATCGGGGGG AGTACAAGGA CAATGCCTTG 
CTGGCTCAGC TGATCCAGGA CAAGCTGGAT GCCTATAAAG CCGACGATCC AACAATGGGG 
GAGGGTCCCG ACAAGGCACG GTCCCAGCTC CTGATCCTGG ATCGTGGCTT TGACCCCAGC 
TCCCCTGTGC TCCATGAACT GACATTCCAG GCTATGAGTT ATGACCTGCT GCCTATCGAA 
AATGATGTTT ACAAGTATGA GACCAGCGGC ATTGGAGAGG CGCGGGTGAA GGAGGTGCTA 
CTGGATGAGG ACGATGACCT GTGGATTGCG CTGCGACACA AGCACATCGC AGAGGTGTCC 
CAGGAAGTCA CCCGGTCTCT GAAGGACTTT TCCTCTAGCA AGAGGATGAA CACTGGCGAG 
AAGACCACCA TGCGGGACCT GTCCCAGATG CTGAAGAAAA TGCCCCAGTA CCAGAAGGAG 
CTCAGCAAGT ATTCGACTCA CCTGCACCTT GCTGAAGACT GCATGAAGCA TTACCAAGGC 
ACTGTAGACA AACTCTGCCG CGTGGAGCAG GACCTGGCAA TGGGCACAGA TGCTGAGGGG 
GAAAAAATCA AGGACCCCAT GAGAGCCATT GTCCCCATCC TGCTGGATGC GAACGTCAGC 
ACTTACGACA AAATCCGTAT CATCCTTCTC TACATCTTCC TGAAGAACGG TATCACTGAG 
GAGAACCTAA ACAAACTCAT CCAGCACGCT CAGATACCCC CAGAGGACAG CGAGATCATC 
ACCAACATGG CTCACCTCGG CGTGCCCATC GTCACGGATT CCACACTACG CCGCCGAAGC 
AAACCGGAGC GGAAGGAGCG TATCAGTGAG CAGACCTACC AGCTCTCACG ATGGACCCCG 
ATCATTAAAG ACATTATGGA GGACACTATC GAAGACAAGC TGGATACAAA GCACTACCCA 
TACATCTCTA CCCGCTCGTC CGCGTCCTTC AGCACCACTG CTGTGAGTGC CCGCTATGGA 
CATTGGCACA AGAATAAGGC CCCCGGGGAG TACCGCAGCG GTCCCCGCCT CATTATTTTC 
ATCCTTGGGG GTGTGAGCCT GAATGAGATG CGCTGTGCTT ACGAAGTGAC CCAGGCCAAC 
GGCAAGTGGG AAGTGCTGAT AGGTTCTACT CACATTCTCA CTCCCACCAA ATTCCTCATG 
GACCTGAGAC ACCCCGACTT CAGGGAGTCC TCTAGGGTAT CTTTTGAGGA TCAGGCTCCA 
ACAATGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Impaired cortico-striatal excitatory transmission triggers epilepsy.
Nature communications10(1)1917(2019 04)
Miyamoto H,Tatsukawa T,Shimohata A,Yamagata T,Suzuki T,Amano K,Mazaki E,Raveau M,Ogiwara I,Oba-Asaka A,Hensch TK,Itohara S,Sakimura K,Kobayashi K,Kobayashi K,Yamakawa K

Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.
JCI insight4(6)(2019 Mar)
Jaramillo AM,Piccotti L,Velasco WV,Delgado ASH,Azzegagh Z,Chung F,Nazeer U,Farooq J,Brenner J,Parker-Thornburg J,Scott BL,Evans CM,Adachi R,Burns AR,Kreda SM,Tuvim MJ,Dickey BF

Syntaxin clusters at secretory granules in a munc18-bound conformation.
Molecular biology of the cell29(22)2700-2708(2018 11)
Yin P,Gandasi NR,Arora S,Omar-Hmeadi M,Saras J,Barg S

Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
Nature communications9(1)3986(2018 09)
Guiberson NGL,Pineda A,Abramov D,Kharel P,Carnazza KE,Wragg RT,Dittman JS,Burré J

Differential gene regulatory plasticity between upper and lower layer cortical excitatory neurons.
Molecular and cellular neurosciences9022-32(2018 May)
Yang L,Chen L,Cai C,Li H

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Stxbp1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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