Srebf2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Srebf2
Entrez Gene ID	20788
Full Name	sterol regulatory element binding factor 2
Synonyms	AI608257,SREBP-2,SREBP2,SREBP2gc,bHLHd2,lop13,nuc
General protein information	Preferred Names sterol regulatory element binding factor 2 Names sterol regulatory element-binding protein 2 srebf2 sterol regulatory element-binding transcription factor 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 E1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006520685.2	XP_006520748.1	sterol regulatory element-binding protein 2 isoform X1
XM_006520685.1	XP_006520748.1	sterol regulatory element-binding protein 2 isoform X1
NM_033218.1	NP_150087.1	sterol regulatory element-binding protein 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SREBF2	XP_849087.3
Danio rerio (zebrafish)	srebf2	NP_001082935.1
Macaca mulatta (Rhesus monkey)	SREBF2	XP_001101257.2
Homo sapiens (human)	SREBF2	NP_004590.2
Pan troglodytes (chimpanzee)	SREBF2	XP_003317335.1
Rattus norvegicus (Norway rat)	Srebf2	NP_001028866.1
Gallus gallus (chicken)	SREBF2	XP_004937758.1
Xenopus tropicalis (tropical clawed frog)	srebf2	NP_001116910.2
Bos taurus (cattle)	SREBF2	NP_001192529.1
Mus musculus (house mouse)	Srebf2	NP_150087.1

Gene Ontology
Bibliography

Related articles in PubMed

The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair.
Kusnadi A, Park SH, Yuan R, Pannellini T, Giannopoulou E, Oliver D, Lu T, Park-Min KH, Ivashkiv LB
Immunity51(2)241-257.e9(2019 08)

Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth.
Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y
Nature communications10(1)37(2019 01)

MicroRNA-98 regulates hepatic cholesterol metabolism via targeting sterol regulatory element-binding protein 2.
Geng C, Dong T, Jin W, Yu B, Yin F, Peng F, Chen G, Ji C, Ding F
Biochemical and biophysical research communications504(2)422-426(2018 10)

The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.
Chan JP, Wong BH, Chin CF, Galam DLA, Foo JC, Wong LC, Ghosh S, Wenk MR, Cazenave-Gassiot A, Silver DL
PLoS biology16(8)e2006443(2018 08)

Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.
Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA
Development (Cambridge, England)145(13)(2018 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Srebf2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Srebf2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15868	NM_033218.1 Latest version!	Mus musculus sterol regulatory element binding factor 2 (Srebf2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OMu51106	XM_006520685.2 Latest version!	Mus musculus sterol regulatory element binding factor 2 (Srebf2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
View Old Accession Versions >>
OMu51106	XM_006520685.1	Mus musculus sterol regulatory element binding factor 2 (Srebf2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Srebf2 ( NM_033218.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_150087.1 Mus musculus sterol regulatory element binding factor 2 (Srebf2), mRNA.

Price & Availability↑

CloneID	OMu15868
Clone ID Related Accession (Same CDS sequence)	NM_033218.1
Accession Version	NM_033218.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576339200000
Organism	Mus musculus(house mouse)
Product	sterol regulatory element-binding protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ965109.1, AF374267.1, AF289715.2, BQ963055.1, CB228109.2 and BG800576.1. On Aug 21, 2005 this sequence version replaced XM_127995.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK172219.1, SRR1660811.128149.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGATGAGA GCAGCGAGCT GGGCGTTCTG GAGACCATGG AGACCCTCAC GGAGCTGGGC 
GATGAGCTGA CTCTCGGGGA CATCGACGAG ATGCTACAGT TTGTCAGCAA TCAAGTGGGA 
GAGTTCCCTG ATTTGTTTTC AGAGCAACTT TGTAGCTCCT TCCCTGGAGG TGGCAGCAAT 
GGTGGCAGTG GCAACAACAG CAGTGGCAGA GGCAACAATG GTGGAGCCAC AGACCCTGCA 
GTACAGCGGT CATTCAGCCA GGTCCCATTA TCTACCTTCT CTCCCTCAGC TGCCTCCCCT 
CAGGCTCCGG CCCTGCAGGT CAAAGTCTCT CCTACCCCAC CAAGGGCAAC CCCTGTTCTC 
CAGCCGCGAC CCCAGCCCCA GCCCCAACCT CCAGCTCAGC TGCAGCAGCA GACGGTGATG 
ATCACCCCGA CGTTCAGCAC CGCTCCGCAG ACGAGGATCA TCCAGCAGCC TTTGATATAC 
CAGAACGCAG CGACCAGCTT TCAAGTCCTG CAGCCTCAAG TGCAAAGCCT CGTGACGTCC 
CCGCAGGTGC AGCCCGTCAC CATCCAGCAG CAGGTGCAGA CGGTACAGGC CCAGCGGGTG 
TTGACGCAGA CAGCCAATGG CACACTGCAG ACCCTTGCCC CCGCCACGGT ACAGACGGTC 
GCTGCGCCAC AGGTGCAGCA GGTCCCGGTC CTGGTGCAAC CTCAGATCAT TAAGACAGAT 
TCCCTTGTGT TGACCACGCT GAAGACAGAT GGCAGCCCTG TCATGGCTGC AGTCCAGAAC 
CCGGCCCTCA CGGCCCTCAC TGCCCCCATC CAGACAGCCG CCCTTCAAGT GCCAACCCTG 
GTGGGCAGCA ACGGGACCAT TCTGACCACA ATGCCTGTGA TGATGGGGCA AGAGAAAGTT 
CCTATCAAGC AAGTGCCTGG CGGCGTGAAG CAGCTGGATC CTCCCAAAGA AGGAGAGAGG 
CGGACAACAC ACAATATCAT TGAAAAGCGC TACCGGTCCT CCATCAACGA CAAAATCATA 
GAGTTGAAGG ACTTAGTCAT GGGGACAGAT GCCAAGATGC ACAAGTCTGG CGTTCTGAGG 
AAGGCCATTG ATTACATCAA ATATCTGCAG CAGGTCAATC ACAAGCTGCG CCAGGAGAAC 
ATGGTGCTGA AGCTGGCCAA TCAGAAAAAC AAGCTCCTGA AGGGCATCGA CCTGGGCAGT 
CTGGTGGACA GTGATGTGGA CTTGAAAATT GATGACTTTA ACCAGAATGT CCTTCTGATG 
TCTCCGCCGG CCTCCGACTC CGGGTCCCAG GCCGGCTTCT CTCCCTATTC CATTGACTCT 
GAGCCGGGCA GCCCTCTGCT GGATGACGCA AAGGTCAAGG ATGAACCGGA CTCTCCTCCT 
GTGGCACTGG GCATGGTGGA CCGCTCTCGA ATCCTCTTAT GTGTCCTCAC CTTCCTGGGC 
CTCTCCTTTA ACCCCTTGAC TTCCTTGCTG CAGTGGGGAG GGGCCCACAA CACTGACCAG 
CACCCATACT CAGGCTCGGG CCGCAGTGTA CTGTCACTGG AGTCAGGTGC TGGGGGCTGG 
TTTGACTGGA TGGTTCCAAC TCTCCTCCTG TGGCTGGTAA ATGGTGTGAT TGTCTTGAGC 
GTCTTTGTGA AGCTGTTGGT CCACGGGGAG CCGGTGATTC GCCCACACTC ACGCCCCTCA 
GTCACCTTCT GGAGACACCG GAAGCAGGCA GACCTAGACC TCGCCAAAGG TGATTTCGCA 
GCTGCTGCTG CCAACCTACA AACCTGCTTA TCCGTGCTGG GCCGGGCGCT GCCCACCTCC 
CGCCTGGACT TGGCCTGCAG CCTCTCCTGG AATGTGATCC GCTACAGCCT GCAGAAGCTG 
CGCCTGGTAC GCTGGTTACT CAAGAAGGTC TTCCAGCGCT GGCGGGCTAC TCCCGCCACT 
GCAGCTGGCT TTGAGGATGA GGCTAAGAGC AGCGCAAGGG ATGCGGCACT GGCCTACCAC 
AGGCTGCACC AGCTGCACAT CACAGGGAAG CTTCCGGCGG GATCTGCCTG TTCAGATGTG 
CACATGGCTC TGTGTGCTGT GAACCTGGCC GAGTGTGCGG AGGAGAAAAT CCTACCAAGC 
ACACTGATTG AGATCCACCT GACAGCGGCC ATGGGGCTCA AGACCCGCTG TGGAGGCAAG 
CTGGGCTTCT TGGCTAGCTA CTTCTTAAAT CGTGCCCAGA GTCTGTGTGG CCCAGAGCAT 
AGCACTGTCC CCGACTCCCT GCGCTGGCTA TGCCATCCCT TGGGCCAGAA GTTTTTCATG 
GAGCGAAGCT GGTCGATCAA GTCAGCAGCC AAGGAGAGCC TGTACTGCGC CCAGAGGAGC 
CCAGCTGACC CCATTGCCCA GGTACACCAG GCGTTCTGCA AAAACCTGCT AGAAAGAGCG 
GTGGAGTCCT TGGTGAAACC TCAGGCCAAG AAGAAGGCAG GCGACCAGGA AGAAGAGAGC 
TGTGAATTTT CCAGTGCTCT AGAGTATTTG AAATTACTTC ATTCTTTTGT GGACTCTGTG 
GGATTTGTGA CCTCACCATT CTCCAGCAGT TCCGTGCTCA GGTCGGCCCT TGGCCCCGAT 
GTCATCTGCC GGTGGTGGAC GTCCGCAGTC ACCATGGCCA TCAGCTGGCT CCAGGGAGAC 
GATGCAGCTG TGCGCTCTCG TTTTACTGAA GTAGAGCGGG TCCCCAAGGC CCTGGAAGTG 
ACCGAGAGTC CCTTGGTGAA GGCCGTCTTC TATACCTGTA GAGCCATGCA TGCCTCCCTC 
TCTGGGAAAG CTGACGGGCA GCAGAACTCC TTCTGTCACT GTGAGAGGGC CAGTGGTCAC 
CTGTGGAGCA GTCTCAACGT CAGCGGCACT ACTTCTGATC CTTCACTTAA CCATGTGATC 
CAGCTGTTCA CCTGTGACCT GCTACTGTCG CTGAGGACAG CACTCTGGCA AAAGCAGGCC 
AGTGCCAGCC AGCTCCTGGG TGAGACCTAC CATGCATCCG GCACTGAGCT GGCCGGCTTC 
CAGCGGGACC TGGGCAGCCT TCGAAGGCTG GCCCATAGCT TCCGCCCAGC CTACCGCAAG 
GTGTTCCTGC ATGAAGCCAC TGTGCGCCTG ATGGCAGGAG CCAGCCCTAC CCGTACACAC 
CAGCTGCTGG AGCATAGCCT ACGGCGGCGC CCCACTCAGA ACACCAAGCA TGGAGAGGTA 
GACACCTGGC CTGGCCAACG AGAGCGAGCT ACTGCCATCC TGCTGGCCTG CCGCCATCTT 
CCCCTCTCTT TCCTGTCTTC CCCGGGCCAG CGGGCAGTGC TGCTGGCTGA AGCTGCCCGC 
ACCCTGGAGA AGGTGGGTGA CCGCCGTTCC TGCAGTGACT GCCAGCAGAT GATTGTCAAG 
CTGGGCGGTG GCACTGCCAT CGCTGCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150087.1
CDS	135..3527
Translation	MDESSELGVLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGGGSNGGSGNNSSGRGNNGGATDPAVQRSFSQVPLSTFSPSAASPQAPALQVKVSPTPPRATPVLQPRPQPQPQPPAQLQQQTVMITPTFSTAPQTRIIQQPLIYQNAATSFQVLQPQVQSLVTSPQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTAPIQTAALQVPTLVGSNGTILTTMPVMMGQEKVPIKQVPGGVKQLDPPKEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNTDQHPYSGSGRSVLSLESGAGGWFDWMVPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRPSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKILPSTLIEIHLTAAMGLKTRCGGKLGFLASYFLNRAQSLCGPEHSTVPDSLRWLCHPLGQKFFMERSWSIKSAAKESLYCAQRSPADPIAQVHQAFCKNLLERAVESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGFVTSPFSSSSVLRSALGPDVICRWWTSAVTMAISWLQGDDAAVRSRFTEVERVPKALEVTESPLVKAVFYTCRAMHASLSGKADGQQNSFCHCERASGHLWSSLNVSGTTSDPSLNHVIQLFTCDLLLSLRTALWQKQASASQLLGETYHASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRPTQNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS

Target ORF information:

RefSeq Version	NM_033218.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sterol regulatory element binding factor 2 (Srebf2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033218.1

ORF Insert Sequence:

ATGGATGAGA GCAGCGAGCT GGGCGTTCTG GAGACCATGG AGACCCTCAC GGAGCTGGGC 
GATGAGCTGA CTCTCGGGGA CATCGACGAG ATGCTACAGT TTGTCAGCAA TCAAGTGGGA 
GAGTTCCCTG ATTTGTTTTC AGAGCAACTT TGTAGCTCCT TCCCTGGAGG TGGCAGCAAT 
GGTGGCAGTG GCAACAACAG CAGTGGCAGA GGCAACAATG GTGGAGCCAC AGACCCTGCA 
GTACAGCGGT CATTCAGCCA GGTCCCATTA TCTACCTTCT CTCCCTCAGC TGCCTCCCCT 
CAGGCTCCGG CCCTGCAGGT CAAAGTCTCT CCTACCCCAC CAAGGGCAAC CCCTGTTCTC 
CAGCCGCGAC CCCAGCCCCA GCCCCAACCT CCAGCTCAGC TGCAGCAGCA GACGGTGATG 
ATCACCCCGA CGTTCAGCAC CGCTCCGCAG ACGAGGATCA TCCAGCAGCC TTTGATATAC 
CAGAACGCAG CGACCAGCTT TCAAGTCCTG CAGCCTCAAG TGCAAAGCCT CGTGACGTCC 
CCGCAGGTGC AGCCCGTCAC CATCCAGCAG CAGGTGCAGA CGGTACAGGC CCAGCGGGTG 
TTGACGCAGA CAGCCAATGG CACACTGCAG ACCCTTGCCC CCGCCACGGT ACAGACGGTC 
GCTGCGCCAC AGGTGCAGCA GGTCCCGGTC CTGGTGCAAC CTCAGATCAT TAAGACAGAT 
TCCCTTGTGT TGACCACGCT GAAGACAGAT GGCAGCCCTG TCATGGCTGC AGTCCAGAAC 
CCGGCCCTCA CGGCCCTCAC TGCCCCCATC CAGACAGCCG CCCTTCAAGT GCCAACCCTG 
GTGGGCAGCA ACGGGACCAT TCTGACCACA ATGCCTGTGA TGATGGGGCA AGAGAAAGTT 
CCTATCAAGC AAGTGCCTGG CGGCGTGAAG CAGCTGGATC CTCCCAAAGA AGGAGAGAGG 
CGGACAACAC ACAATATCAT TGAAAAGCGC TACCGGTCCT CCATCAACGA CAAAATCATA 
GAGTTGAAGG ACTTAGTCAT GGGGACAGAT GCCAAGATGC ACAAGTCTGG CGTTCTGAGG 
AAGGCCATTG ATTACATCAA ATATCTGCAG CAGGTCAATC ACAAGCTGCG CCAGGAGAAC 
ATGGTGCTGA AGCTGGCCAA TCAGAAAAAC AAGCTCCTGA AGGGCATCGA CCTGGGCAGT 
CTGGTGGACA GTGATGTGGA CTTGAAAATT GATGACTTTA ACCAGAATGT CCTTCTGATG 
TCTCCGCCGG CCTCCGACTC CGGGTCCCAG GCCGGCTTCT CTCCCTATTC CATTGACTCT 
GAGCCGGGCA GCCCTCTGCT GGATGACGCA AAGGTCAAGG ATGAACCGGA CTCTCCTCCT 
GTGGCACTGG GCATGGTGGA CCGCTCTCGA ATCCTCTTAT GTGTCCTCAC CTTCCTGGGC 
CTCTCCTTTA ACCCCTTGAC TTCCTTGCTG CAGTGGGGAG GGGCCCACAA CACTGACCAG 
CACCCATACT CAGGCTCGGG CCGCAGTGTA CTGTCACTGG AGTCAGGTGC TGGGGGCTGG 
TTTGACTGGA TGGTTCCAAC TCTCCTCCTG TGGCTGGTAA ATGGTGTGAT TGTCTTGAGC 
GTCTTTGTGA AGCTGTTGGT CCACGGGGAG CCGGTGATTC GCCCACACTC ACGCCCCTCA 
GTCACCTTCT GGAGACACCG GAAGCAGGCA GACCTAGACC TCGCCAAAGG TGATTTCGCA 
GCTGCTGCTG CCAACCTACA AACCTGCTTA TCCGTGCTGG GCCGGGCGCT GCCCACCTCC 
CGCCTGGACT TGGCCTGCAG CCTCTCCTGG AATGTGATCC GCTACAGCCT GCAGAAGCTG 
CGCCTGGTAC GCTGGTTACT CAAGAAGGTC TTCCAGCGCT GGCGGGCTAC TCCCGCCACT 
GCAGCTGGCT TTGAGGATGA GGCTAAGAGC AGCGCAAGGG ATGCGGCACT GGCCTACCAC 
AGGCTGCACC AGCTGCACAT CACAGGGAAG CTTCCGGCGG GATCTGCCTG TTCAGATGTG 
CACATGGCTC TGTGTGCTGT GAACCTGGCC GAGTGTGCGG AGGAGAAAAT CCTACCAAGC 
ACACTGATTG AGATCCACCT GACAGCGGCC ATGGGGCTCA AGACCCGCTG TGGAGGCAAG 
CTGGGCTTCT TGGCTAGCTA CTTCTTAAAT CGTGCCCAGA GTCTGTGTGG CCCAGAGCAT 
AGCACTGTCC CCGACTCCCT GCGCTGGCTA TGCCATCCCT TGGGCCAGAA GTTTTTCATG 
GAGCGAAGCT GGTCGATCAA GTCAGCAGCC AAGGAGAGCC TGTACTGCGC CCAGAGGAGC 
CCAGCTGACC CCATTGCCCA GGTACACCAG GCGTTCTGCA AAAACCTGCT AGAAAGAGCG 
GTGGAGTCCT TGGTGAAACC TCAGGCCAAG AAGAAGGCAG GCGACCAGGA AGAAGAGAGC 
TGTGAATTTT CCAGTGCTCT AGAGTATTTG AAATTACTTC ATTCTTTTGT GGACTCTGTG 
GGATTTGTGA CCTCACCATT CTCCAGCAGT TCCGTGCTCA GGTCGGCCCT TGGCCCCGAT 
GTCATCTGCC GGTGGTGGAC GTCCGCAGTC ACCATGGCCA TCAGCTGGCT CCAGGGAGAC 
GATGCAGCTG TGCGCTCTCG TTTTACTGAA GTAGAGCGGG TCCCCAAGGC CCTGGAAGTG 
ACCGAGAGTC CCTTGGTGAA GGCCGTCTTC TATACCTGTA GAGCCATGCA TGCCTCCCTC 
TCTGGGAAAG CTGACGGGCA GCAGAACTCC TTCTGTCACT GTGAGAGGGC CAGTGGTCAC 
CTGTGGAGCA GTCTCAACGT CAGCGGCACT ACTTCTGATC CTTCACTTAA CCATGTGATC 
CAGCTGTTCA CCTGTGACCT GCTACTGTCG CTGAGGACAG CACTCTGGCA AAAGCAGGCC 
AGTGCCAGCC AGCTCCTGGG TGAGACCTAC CATGCATCCG GCACTGAGCT GGCCGGCTTC 
CAGCGGGACC TGGGCAGCCT TCGAAGGCTG GCCCATAGCT TCCGCCCAGC CTACCGCAAG 
GTGTTCCTGC ATGAAGCCAC TGTGCGCCTG ATGGCAGGAG CCAGCCCTAC CCGTACACAC 
CAGCTGCTGG AGCATAGCCT ACGGCGGCGC CCCACTCAGA ACACCAAGCA TGGAGAGGTA 
GACACCTGGC CTGGCCAACG AGAGCGAGCT ACTGCCATCC TGCTGGCCTG CCGCCATCTT 
CCCCTCTCTT TCCTGTCTTC CCCGGGCCAG CGGGCAGTGC TGCTGGCTGA AGCTGCCCGC 
ACCCTGGAGA AGGTGGGTGA CCGCCGTTCC TGCAGTGACT GCCAGCAGAT GATTGTCAAG 
CTGGGCGGTG GCACTGCCAT CGCTGCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Srebf2 ( XM_006520685.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520748.1 Mus musculus sterol regulatory element binding factor 2 (Srebf2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51106
Clone ID Related Accession (Same CDS sequence)	XM_006520685.2 , XM_006520685.1
Accession Version	XM_006520685.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3303bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	sterol regulatory element-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006520685.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTACAGT TTGTCAGCAA TCAAGTGGGA GAGTTCCCTG ATTTGTTTTC AGAGCAACTT 
TGTAGCTCCT TCCCTGGAGG TGGCAGCAAT GGTGGCAGTG GCAACAACAG CAGTGGCAGA 
GGCAACAATG GTGGAGCCAC AGACCCTGCA GTACAGCGGT CATTCAGCCA GGTCCCATTA 
TCTACCTTCT CTCCCTCAGC TGCCTCCCCT CAGGCTCCGG CCCTGCAGGT CAAAGTCTCT 
CCTACCCCAC CAAGGGCAAC CCCTGTTCTC CAGCCGCGAC CCCAGCCCCA GCCCCAACCT 
CCAGCTCAGC TGCAGCAGCA GACGGTGATG ATCACCCCGA CGTTCAGCAC CGCTCCGCAG 
ACGAGGATCA TCCAGCAGCC TTTGATATAC CAGAACGCAG CGACCAGCTT TCAAGTCCTG 
CAGCCTCAAG TGCAAAGCCT CGTGACGTCC CCGCAGGTGC AGCCCGTCAC CATCCAGCAG 
CAGGTGCAGA CGGTACAGGC CCAGCGGGTG TTGACGCAGA CAGCCAATGG CACACTGCAG 
ACCCTTGCCC CCGCCACGGT ACAGACGGTC GCTGCGCCAC AGGTGCAGCA GGTCCCGGTC 
CTGGTGCAAC CTCAGATCAT TAAGACAGAT TCCCTTGTGT TGACCACGCT GAAGACAGAT 
GGCAGCCCTG TCATGGCTGC AGTCCAGAAC CCGGCCCTCA CGGCCCTCAC TGCCCCCATC 
CAGACAGCCG CCCTTCAAGT GCCAACCCTG GTGGGCAGCA ACGGGACCAT TCTGACCACA 
ATGCCTGTGA TGATGGGGCA AGAGAAAGTT CCTATCAAGC AAGTGCCTGG CGGCGTGAAG 
CAGCTGGATC CTCCCAAAGA AGGAGAGAGG CGGACAACAC ACAATATCAT TGAAAAGCGC 
TACCGGTCCT CCATCAACGA CAAAATCATA GAGTTGAAGG ACTTAGTCAT GGGGACAGAT 
GCCAAGATGC ACAAGTCTGG CGTTCTGAGG AAGGCCATTG ATTACATCAA ATATCTGCAG 
CAGGTCAATC ACAAGCTGCG CCAGGAGAAC ATGGTGCTGA AGCTGGCCAA TCAGAAAAAC 
AAGCTCCTGA AGGGCATCGA CCTGGGCAGT CTGGTGGACA GTGATGTGGA CTTGAAAATT 
GATGACTTTA ACCAGAATGT CCTTCTGATG TCTCCGCCGG CCTCCGACTC CGGGTCCCAG 
GCCGGCTTCT CTCCCTATTC CATTGACTCT GAGCCGGGCA GCCCTCTGCT GGATGACGCA 
AAGGTCAAGG ATGAACCGGA CTCTCCTCCT GTGGCACTGG GCATGGTGGA CCGCTCTCGA 
ATCCTCTTAT GTGTCCTCAC CTTCCTGGGC CTCTCCTTTA ACCCCTTGAC TTCCTTGCTG 
CAGTGGGGAG GGGCCCACAA CACTGACCAG CACCCATACT CAGGCTCGGG CCGCAGTGTA 
CTGTCACTGG AGTCAGGTGC TGGGGGCTGG TTTGACTGGA TGGTTCCAAC TCTCCTCCTG 
TGGCTGGTAA ATGGTGTGAT TGTCTTGAGC GTCTTTGTGA AGCTGTTGGT CCACGGGGAG 
CCGGTGATTC GCCCACACTC ACGCCCCTCA GTCACCTTCT GGAGACACCG GAAGCAGGCA 
GACCTAGACC TCGCCAAAGG TGATTTCGCA GCTGCTGCTG CCAACCTACA AACCTGCTTA 
TCCGTGCTGG GCCGGGCGCT GCCCACCTCC CGCCTGGACT TGGCCTGCAG CCTCTCCTGG 
AATGTGATCC GCTACAGCCT GCAGAAGCTG CGCCTGGTAC GCTGGTTACT CAAGAAGGTC 
TTCCAGCGCT GGCGGGCTAC TCCCGCCACT GCAGCTGGCT TTGAGGATGA GGCTAAGAGC 
AGCGCAAGGG ATGCGGCACT GGCCTACCAC AGGCTGCACC AGCTGCACAT CACAGGGAAG 
CTTCCGGCGG GATCTGCCTG TTCAGATGTG CACATGGCTC TGTGTGCTGT GAACCTGGCC 
GAGTGTGCGG AGGAGAAAAT CCTACCAAGC ACACTGATTG AGATCCACCT GACAGCGGCC 
ATGGGGCTCA AGACCCGCTG TGGAGGCAAG CTGGGCTTCT TGGCTAGCTA CTTCTTAAAT 
CGTGCCCAGA GTCTGTGTGG CCCAGAGCAT AGCACTGTCC CCGACTCCCT GCGCTGGCTA 
TGCCATCCCT TGGGCCAGAA GTTTTTCATG GAGCGAAGCT GGTCGATCAA GTCAGCAGCC 
AAGGAGAGCC TGTACTGCGC CCAGAGGAGC CCAGCTGACC CCATTGCCCA GGTACACCAG 
GCGTTCTGCA AAAACCTGCT AGAAAGAGCG GTGGAGTCCT TGGTGAAACC TCAGGCCAAG 
AAGAAGGCAG GCGACCAGGA AGAAGAGAGC TGTGAATTTT CCAGTGCTCT AGAGTATTTG 
AAATTACTTC ATTCTTTTGT GGACTCTGTG GGATTTGTGA CCTCACCATT CTCCAGCAGT 
TCCGTGCTCA GGTCGGCCCT TGGCCCCGAT GTCATCTGCC GGTGGTGGAC GTCCGCAGTC 
ACCATGGCCA TCAGCTGGCT CCAGGGAGAC GATGCAGCTG TGCGCTCTCG TTTTACTGAA 
GTAGAGCGGG TCCCCAAGGC CCTGGAAGTG ACCGAGAGTC CCTTGGTGAA GGCCGTCTTC 
TATACCTGTA GAGCCATGCA TGCCTCCCTC TCTGGGAAAG CTGACGGGCA GCAGAACTCC 
TTCTGTCACT GTGAGAGGGC CAGTGGTCAC CTGTGGAGCA GTCTCAACGT CAGCGGCACT 
ACTTCTGATC CTTCACTTAA CCATGTGATC CAGCTGTTCA CCTGTGACCT GCTACTGTCG 
CTGAGGACAG CACTCTGGCA AAAGCAGGCC AGTGCCAGCC AGCTCCTGGG TGAGACCTAC 
CATGCATCCG GCACTGAGCT GGCCGGCTTC CAGCGGGACC TGGGCAGCCT TCGAAGGCTG 
GCCCATAGCT TCCGCCCAGC CTACCGCAAG GTGTTCCTGC ATGAAGCCAC TGTGCGCCTG 
ATGGCAGGAG CCAGCCCTAC CCGTACACAC CAGCTGCTGG AGCATAGCCT ACGGCGGCGC 
CCCACTCAGA ACACCAAGCA TGGAGAGGTA GACACCTGGC CTGGCCAACG AGAGCGAGCT 
ACTGCCATCC TGCTGGCCTG CCGCCATCTT CCCCTCTCTT TCCTGTCTTC CCCGGGCCAG 
CGGGCAGTGC TGCTGGCTGA AGCTGCCCGC ACCCTGGAGA AGGTGGGTGA CCGCCGTTCC 
TGCAGTGACT GCCAGCAGAT GATTGTCAAG CTGGGCGGTG GCACTGCCAT CGCTGCCTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520748.1
CDS	631..3933
Translation	MLQFVSNQVGEFPDLFSEQLCSSFPGGGSNGGSGNNSSGRGNNGGATDPAVQRSFSQVPLSTFSPSAASPQAPALQVKVSPTPPRATPVLQPRPQPQPQPPAQLQQQTVMITPTFSTAPQTRIIQQPLIYQNAATSFQVLQPQVQSLVTSPQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTAPIQTAALQVPTLVGSNGTILTTMPVMMGQEKVPIKQVPGGVKQLDPPKEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNTDQHPYSGSGRSVLSLESGAGGWFDWMVPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRPSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKILPSTLIEIHLTAAMGLKTRCGGKLGFLASYFLNRAQSLCGPEHSTVPDSLRWLCHPLGQKFFMERSWSIKSAAKESLYCAQRSPADPIAQVHQAFCKNLLERAVESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGFVTSPFSSSSVLRSALGPDVICRWWTSAVTMAISWLQGDDAAVRSRFTEVERVPKALEVTESPLVKAVFYTCRAMHASLSGKADGQQNSFCHCERASGHLWSSLNVSGTTSDPSLNHVIQLFTCDLLLSLRTALWQKQASASQLLGETYHASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRPTQNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS

Target ORF information:

RefSeq Version	XM_006520685.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sterol regulatory element binding factor 2 (Srebf2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520685.2

ORF Insert Sequence:

ATGCTACAGT TTGTCAGCAA TCAAGTGGGA GAGTTCCCTG ATTTGTTTTC AGAGCAACTT 
TGTAGCTCCT TCCCTGGAGG TGGCAGCAAT GGTGGCAGTG GCAACAACAG CAGTGGCAGA 
GGCAACAATG GTGGAGCCAC AGACCCTGCA GTACAGCGGT CATTCAGCCA GGTCCCATTA 
TCTACCTTCT CTCCCTCAGC TGCCTCCCCT CAGGCTCCGG CCCTGCAGGT CAAAGTCTCT 
CCTACCCCAC CAAGGGCAAC CCCTGTTCTC CAGCCGCGAC CCCAGCCCCA GCCCCAACCT 
CCAGCTCAGC TGCAGCAGCA GACGGTGATG ATCACCCCGA CGTTCAGCAC CGCTCCGCAG 
ACGAGGATCA TCCAGCAGCC TTTGATATAC CAGAACGCAG CGACCAGCTT TCAAGTCCTG 
CAGCCTCAAG TGCAAAGCCT CGTGACGTCC CCGCAGGTGC AGCCCGTCAC CATCCAGCAG 
CAGGTGCAGA CGGTACAGGC CCAGCGGGTG TTGACGCAGA CAGCCAATGG CACACTGCAG 
ACCCTTGCCC CCGCCACGGT ACAGACGGTC GCTGCGCCAC AGGTGCAGCA GGTCCCGGTC 
CTGGTGCAAC CTCAGATCAT TAAGACAGAT TCCCTTGTGT TGACCACGCT GAAGACAGAT 
GGCAGCCCTG TCATGGCTGC AGTCCAGAAC CCGGCCCTCA CGGCCCTCAC TGCCCCCATC 
CAGACAGCCG CCCTTCAAGT GCCAACCCTG GTGGGCAGCA ACGGGACCAT TCTGACCACA 
ATGCCTGTGA TGATGGGGCA AGAGAAAGTT CCTATCAAGC AAGTGCCTGG CGGCGTGAAG 
CAGCTGGATC CTCCCAAAGA AGGAGAGAGG CGGACAACAC ACAATATCAT TGAAAAGCGC 
TACCGGTCCT CCATCAACGA CAAAATCATA GAGTTGAAGG ACTTAGTCAT GGGGACAGAT 
GCCAAGATGC ACAAGTCTGG CGTTCTGAGG AAGGCCATTG ATTACATCAA ATATCTGCAG 
CAGGTCAATC ACAAGCTGCG CCAGGAGAAC ATGGTGCTGA AGCTGGCCAA TCAGAAAAAC 
AAGCTCCTGA AGGGCATCGA CCTGGGCAGT CTGGTGGACA GTGATGTGGA CTTGAAAATT 
GATGACTTTA ACCAGAATGT CCTTCTGATG TCTCCGCCGG CCTCCGACTC CGGGTCCCAG 
GCCGGCTTCT CTCCCTATTC CATTGACTCT GAGCCGGGCA GCCCTCTGCT GGATGACGCA 
AAGGTCAAGG ATGAACCGGA CTCTCCTCCT GTGGCACTGG GCATGGTGGA CCGCTCTCGA 
ATCCTCTTAT GTGTCCTCAC CTTCCTGGGC CTCTCCTTTA ACCCCTTGAC TTCCTTGCTG 
CAGTGGGGAG GGGCCCACAA CACTGACCAG CACCCATACT CAGGCTCGGG CCGCAGTGTA 
CTGTCACTGG AGTCAGGTGC TGGGGGCTGG TTTGACTGGA TGGTTCCAAC TCTCCTCCTG 
TGGCTGGTAA ATGGTGTGAT TGTCTTGAGC GTCTTTGTGA AGCTGTTGGT CCACGGGGAG 
CCGGTGATTC GCCCACACTC ACGCCCCTCA GTCACCTTCT GGAGACACCG GAAGCAGGCA 
GACCTAGACC TCGCCAAAGG TGATTTCGCA GCTGCTGCTG CCAACCTACA AACCTGCTTA 
TCCGTGCTGG GCCGGGCGCT GCCCACCTCC CGCCTGGACT TGGCCTGCAG CCTCTCCTGG 
AATGTGATCC GCTACAGCCT GCAGAAGCTG CGCCTGGTAC GCTGGTTACT CAAGAAGGTC 
TTCCAGCGCT GGCGGGCTAC TCCCGCCACT GCAGCTGGCT TTGAGGATGA GGCTAAGAGC 
AGCGCAAGGG ATGCGGCACT GGCCTACCAC AGGCTGCACC AGCTGCACAT CACAGGGAAG 
CTTCCGGCGG GATCTGCCTG TTCAGATGTG CACATGGCTC TGTGTGCTGT GAACCTGGCC 
GAGTGTGCGG AGGAGAAAAT CCTACCAAGC ACACTGATTG AGATCCACCT GACAGCGGCC 
ATGGGGCTCA AGACCCGCTG TGGAGGCAAG CTGGGCTTCT TGGCTAGCTA CTTCTTAAAT 
CGTGCCCAGA GTCTGTGTGG CCCAGAGCAT AGCACTGTCC CCGACTCCCT GCGCTGGCTA 
TGCCATCCCT TGGGCCAGAA GTTTTTCATG GAGCGAAGCT GGTCGATCAA GTCAGCAGCC 
AAGGAGAGCC TGTACTGCGC CCAGAGGAGC CCAGCTGACC CCATTGCCCA GGTACACCAG 
GCGTTCTGCA AAAACCTGCT AGAAAGAGCG GTGGAGTCCT TGGTGAAACC TCAGGCCAAG 
AAGAAGGCAG GCGACCAGGA AGAAGAGAGC TGTGAATTTT CCAGTGCTCT AGAGTATTTG 
AAATTACTTC ATTCTTTTGT GGACTCTGTG GGATTTGTGA CCTCACCATT CTCCAGCAGT 
TCCGTGCTCA GGTCGGCCCT TGGCCCCGAT GTCATCTGCC GGTGGTGGAC GTCCGCAGTC 
ACCATGGCCA TCAGCTGGCT CCAGGGAGAC GATGCAGCTG TGCGCTCTCG TTTTACTGAA 
GTAGAGCGGG TCCCCAAGGC CCTGGAAGTG ACCGAGAGTC CCTTGGTGAA GGCCGTCTTC 
TATACCTGTA GAGCCATGCA TGCCTCCCTC TCTGGGAAAG CTGACGGGCA GCAGAACTCC 
TTCTGTCACT GTGAGAGGGC CAGTGGTCAC CTGTGGAGCA GTCTCAACGT CAGCGGCACT 
ACTTCTGATC CTTCACTTAA CCATGTGATC CAGCTGTTCA CCTGTGACCT GCTACTGTCG 
CTGAGGACAG CACTCTGGCA AAAGCAGGCC AGTGCCAGCC AGCTCCTGGG TGAGACCTAC 
CATGCATCCG GCACTGAGCT GGCCGGCTTC CAGCGGGACC TGGGCAGCCT TCGAAGGCTG 
GCCCATAGCT TCCGCCCAGC CTACCGCAAG GTGTTCCTGC ATGAAGCCAC TGTGCGCCTG 
ATGGCAGGAG CCAGCCCTAC CCGTACACAC CAGCTGCTGG AGCATAGCCT ACGGCGGCGC 
CCCACTCAGA ACACCAAGCA TGGAGAGGTA GACACCTGGC CTGGCCAACG AGAGCGAGCT 
ACTGCCATCC TGCTGGCCTG CCGCCATCTT CCCCTCTCTT TCCTGTCTTC CCCGGGCCAG 
CGGGCAGTGC TGCTGGCTGA AGCTGCCCGC ACCCTGGAGA AGGTGGGTGA CCGCCGTTCC 
TGCAGTGACT GCCAGCAGAT GATTGTCAAG CTGGGCGGTG GCACTGCCAT CGCTGCCTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Srebf2 ( XM_006520685.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520748.1 Mus musculus sterol regulatory element binding factor 2 (Srebf2), transcript variant X1, mRNA.

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CloneID	OMu51106
Clone ID Related Accession (Same CDS sequence)	XM_006520685.2 , XM_006520685.1
Accession Version	XM_006520685.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3303bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	sterol regulatory element-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTACAGT TTGTCAGCAA TCAAGTGGGA GAGTTCCCTG ATTTGTTTTC AGAGCAACTT 
TGTAGCTCCT TCCCTGGAGG TGGCAGCAAT GGTGGCAGTG GCAACAACAG CAGTGGCAGA 
GGCAACAATG GTGGAGCCAC AGACCCTGCA GTACAGCGGT CATTCAGCCA GGTCCCATTA 
TCTACCTTCT CTCCCTCAGC TGCCTCCCCT CAGGCTCCGG CCCTGCAGGT CAAAGTCTCT 
CCTACCCCAC CAAGGGCAAC CCCTGTTCTC CAGCCGCGAC CCCAGCCCCA GCCCCAACCT 
CCAGCTCAGC TGCAGCAGCA GACGGTGATG ATCACCCCGA CGTTCAGCAC CGCTCCGCAG 
ACGAGGATCA TCCAGCAGCC TTTGATATAC CAGAACGCAG CGACCAGCTT TCAAGTCCTG 
CAGCCTCAAG TGCAAAGCCT CGTGACGTCC CCGCAGGTGC AGCCCGTCAC CATCCAGCAG 
CAGGTGCAGA CGGTACAGGC CCAGCGGGTG TTGACGCAGA CAGCCAATGG CACACTGCAG 
ACCCTTGCCC CCGCCACGGT ACAGACGGTC GCTGCGCCAC AGGTGCAGCA GGTCCCGGTC 
CTGGTGCAAC CTCAGATCAT TAAGACAGAT TCCCTTGTGT TGACCACGCT GAAGACAGAT 
GGCAGCCCTG TCATGGCTGC AGTCCAGAAC CCGGCCCTCA CGGCCCTCAC TGCCCCCATC 
CAGACAGCCG CCCTTCAAGT GCCAACCCTG GTGGGCAGCA ACGGGACCAT TCTGACCACA 
ATGCCTGTGA TGATGGGGCA AGAGAAAGTT CCTATCAAGC AAGTGCCTGG CGGCGTGAAG 
CAGCTGGATC CTCCCAAAGA AGGAGAGAGG CGGACAACAC ACAATATCAT TGAAAAGCGC 
TACCGGTCCT CCATCAACGA CAAAATCATA GAGTTGAAGG ACTTAGTCAT GGGGACAGAT 
GCCAAGATGC ACAAGTCTGG CGTTCTGAGG AAGGCCATTG ATTACATCAA ATATCTGCAG 
CAGGTCAATC ACAAGCTGCG CCAGGAGAAC ATGGTGCTGA AGCTGGCCAA TCAGAAAAAC 
AAGCTCCTGA AGGGCATCGA CCTGGGCAGT CTGGTGGACA GTGATGTGGA CTTGAAAATT 
GATGACTTTA ACCAGAATGT CCTTCTGATG TCTCCGCCGG CCTCCGACTC CGGGTCCCAG 
GCCGGCTTCT CTCCCTATTC CATTGACTCT GAGCCGGGCA GCCCTCTGCT GGATGACGCA 
AAGGTCAAGG ATGAACCGGA CTCTCCTCCT GTGGCACTGG GCATGGTGGA CCGCTCTCGA 
ATCCTCTTAT GTGTCCTCAC CTTCCTGGGC CTCTCCTTTA ACCCCTTGAC TTCCTTGCTG 
CAGTGGGGAG GGGCCCACAA CACTGACCAG CACCCATACT CAGGCTCGGG CCGCAGTGTA 
CTGTCACTGG AGTCAGGTGC TGGGGGCTGG TTTGACTGGA TGGTTCCAAC TCTCCTCCTG 
TGGCTGGTAA ATGGTGTGAT TGTCTTGAGC GTCTTTGTGA AGCTGTTGGT CCACGGGGAG 
CCGGTGATTC GCCCACACTC ACGCCCCTCA GTCACCTTCT GGAGACACCG GAAGCAGGCA 
GACCTAGACC TCGCCAAAGG TGATTTCGCA GCTGCTGCTG CCAACCTACA AACCTGCTTA 
TCCGTGCTGG GCCGGGCGCT GCCCACCTCC CGCCTGGACT TGGCCTGCAG CCTCTCCTGG 
AATGTGATCC GCTACAGCCT GCAGAAGCTG CGCCTGGTAC GCTGGTTACT CAAGAAGGTC 
TTCCAGCGCT GGCGGGCTAC TCCCGCCACT GCAGCTGGCT TTGAGGATGA GGCTAAGAGC 
AGCGCAAGGG ATGCGGCACT GGCCTACCAC AGGCTGCACC AGCTGCACAT CACAGGGAAG 
CTTCCGGCGG GATCTGCCTG TTCAGATGTG CACATGGCTC TGTGTGCTGT GAACCTGGCC 
GAGTGTGCGG AGGAGAAAAT CCTACCAAGC ACACTGATTG AGATCCACCT GACAGCGGCC 
ATGGGGCTCA AGACCCGCTG TGGAGGCAAG CTGGGCTTCT TGGCTAGCTA CTTCTTAAAT 
CGTGCCCAGA GTCTGTGTGG CCCAGAGCAT AGCACTGTCC CCGACTCCCT GCGCTGGCTA 
TGCCATCCCT TGGGCCAGAA GTTTTTCATG GAGCGAAGCT GGTCGATCAA GTCAGCAGCC 
AAGGAGAGCC TGTACTGCGC CCAGAGGAGC CCAGCTGACC CCATTGCCCA GGTACACCAG 
GCGTTCTGCA AAAACCTGCT AGAAAGAGCG GTGGAGTCCT TGGTGAAACC TCAGGCCAAG 
AAGAAGGCAG GCGACCAGGA AGAAGAGAGC TGTGAATTTT CCAGTGCTCT AGAGTATTTG 
AAATTACTTC ATTCTTTTGT GGACTCTGTG GGATTTGTGA CCTCACCATT CTCCAGCAGT 
TCCGTGCTCA GGTCGGCCCT TGGCCCCGAT GTCATCTGCC GGTGGTGGAC GTCCGCAGTC 
ACCATGGCCA TCAGCTGGCT CCAGGGAGAC GATGCAGCTG TGCGCTCTCG TTTTACTGAA 
GTAGAGCGGG TCCCCAAGGC CCTGGAAGTG ACCGAGAGTC CCTTGGTGAA GGCCGTCTTC 
TATACCTGTA GAGCCATGCA TGCCTCCCTC TCTGGGAAAG CTGACGGGCA GCAGAACTCC 
TTCTGTCACT GTGAGAGGGC CAGTGGTCAC CTGTGGAGCA GTCTCAACGT CAGCGGCACT 
ACTTCTGATC CTTCACTTAA CCATGTGATC CAGCTGTTCA CCTGTGACCT GCTACTGTCG 
CTGAGGACAG CACTCTGGCA AAAGCAGGCC AGTGCCAGCC AGCTCCTGGG TGAGACCTAC 
CATGCATCCG GCACTGAGCT GGCCGGCTTC CAGCGGGACC TGGGCAGCCT TCGAAGGCTG 
GCCCATAGCT TCCGCCCAGC CTACCGCAAG GTGTTCCTGC ATGAAGCCAC TGTGCGCCTG 
ATGGCAGGAG CCAGCCCTAC CCGTACACAC CAGCTGCTGG AGCATAGCCT ACGGCGGCGC 
CCCACTCAGA ACACCAAGCA TGGAGAGGTA GACACCTGGC CTGGCCAACG AGAGCGAGCT 
ACTGCCATCC TGCTGGCCTG CCGCCATCTT CCCCTCTCTT TCCTGTCTTC CCCGGGCCAG 
CGGGCAGTGC TGCTGGCTGA AGCTGCCCGC ACCCTGGAGA AGGTGGGTGA CCGCCGTTCC 
TGCAGTGACT GCCAGCAGAT GATTGTCAAG CTGGGCGGTG GCACTGCCAT CGCTGCCTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520748.1
CDS	561..3863
Translation	MLQFVSNQVGEFPDLFSEQLCSSFPGGGSNGGSGNNSSGRGNNGGATDPAVQRSFSQVPLSTFSPSAASPQAPALQVKVSPTPPRATPVLQPRPQPQPQPPAQLQQQTVMITPTFSTAPQTRIIQQPLIYQNAATSFQVLQPQVQSLVTSPQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTAPIQTAALQVPTLVGSNGTILTTMPVMMGQEKVPIKQVPGGVKQLDPPKEGERRTTHNIIEKRYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLGLSFNPLTSLLQWGGAHNTDQHPYSGSGRSVLSLESGAGGWFDWMVPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRPSVTFWRHRKQADLDLAKGDFAAAAANLQTCLSVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQRWRATPATAAGFEDEAKSSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKILPSTLIEIHLTAAMGLKTRCGGKLGFLASYFLNRAQSLCGPEHSTVPDSLRWLCHPLGQKFFMERSWSIKSAAKESLYCAQRSPADPIAQVHQAFCKNLLERAVESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGFVTSPFSSSSVLRSALGPDVICRWWTSAVTMAISWLQGDDAAVRSRFTEVERVPKALEVTESPLVKAVFYTCRAMHASLSGKADGQQNSFCHCERASGHLWSSLNVSGTTSDPSLNHVIQLFTCDLLLSLRTALWQKQASASQLLGETYHASGTELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRPTQNTKHGEVDTWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCSDCQQMIVKLGGGTAIAAS

Target ORF information:

RefSeq Version	XM_006520685.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sterol regulatory element binding factor 2 (Srebf2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520685.1

ORF Insert Sequence:

ATGCTACAGT TTGTCAGCAA TCAAGTGGGA GAGTTCCCTG ATTTGTTTTC AGAGCAACTT 
TGTAGCTCCT TCCCTGGAGG TGGCAGCAAT GGTGGCAGTG GCAACAACAG CAGTGGCAGA 
GGCAACAATG GTGGAGCCAC AGACCCTGCA GTACAGCGGT CATTCAGCCA GGTCCCATTA 
TCTACCTTCT CTCCCTCAGC TGCCTCCCCT CAGGCTCCGG CCCTGCAGGT CAAAGTCTCT 
CCTACCCCAC CAAGGGCAAC CCCTGTTCTC CAGCCGCGAC CCCAGCCCCA GCCCCAACCT 
CCAGCTCAGC TGCAGCAGCA GACGGTGATG ATCACCCCGA CGTTCAGCAC CGCTCCGCAG 
ACGAGGATCA TCCAGCAGCC TTTGATATAC CAGAACGCAG CGACCAGCTT TCAAGTCCTG 
CAGCCTCAAG TGCAAAGCCT CGTGACGTCC CCGCAGGTGC AGCCCGTCAC CATCCAGCAG 
CAGGTGCAGA CGGTACAGGC CCAGCGGGTG TTGACGCAGA CAGCCAATGG CACACTGCAG 
ACCCTTGCCC CCGCCACGGT ACAGACGGTC GCTGCGCCAC AGGTGCAGCA GGTCCCGGTC 
CTGGTGCAAC CTCAGATCAT TAAGACAGAT TCCCTTGTGT TGACCACGCT GAAGACAGAT 
GGCAGCCCTG TCATGGCTGC AGTCCAGAAC CCGGCCCTCA CGGCCCTCAC TGCCCCCATC 
CAGACAGCCG CCCTTCAAGT GCCAACCCTG GTGGGCAGCA ACGGGACCAT TCTGACCACA 
ATGCCTGTGA TGATGGGGCA AGAGAAAGTT CCTATCAAGC AAGTGCCTGG CGGCGTGAAG 
CAGCTGGATC CTCCCAAAGA AGGAGAGAGG CGGACAACAC ACAATATCAT TGAAAAGCGC 
TACCGGTCCT CCATCAACGA CAAAATCATA GAGTTGAAGG ACTTAGTCAT GGGGACAGAT 
GCCAAGATGC ACAAGTCTGG CGTTCTGAGG AAGGCCATTG ATTACATCAA ATATCTGCAG 
CAGGTCAATC ACAAGCTGCG CCAGGAGAAC ATGGTGCTGA AGCTGGCCAA TCAGAAAAAC 
AAGCTCCTGA AGGGCATCGA CCTGGGCAGT CTGGTGGACA GTGATGTGGA CTTGAAAATT 
GATGACTTTA ACCAGAATGT CCTTCTGATG TCTCCGCCGG CCTCCGACTC CGGGTCCCAG 
GCCGGCTTCT CTCCCTATTC CATTGACTCT GAGCCGGGCA GCCCTCTGCT GGATGACGCA 
AAGGTCAAGG ATGAACCGGA CTCTCCTCCT GTGGCACTGG GCATGGTGGA CCGCTCTCGA 
ATCCTCTTAT GTGTCCTCAC CTTCCTGGGC CTCTCCTTTA ACCCCTTGAC TTCCTTGCTG 
CAGTGGGGAG GGGCCCACAA CACTGACCAG CACCCATACT CAGGCTCGGG CCGCAGTGTA 
CTGTCACTGG AGTCAGGTGC TGGGGGCTGG TTTGACTGGA TGGTTCCAAC TCTCCTCCTG 
TGGCTGGTAA ATGGTGTGAT TGTCTTGAGC GTCTTTGTGA AGCTGTTGGT CCACGGGGAG 
CCGGTGATTC GCCCACACTC ACGCCCCTCA GTCACCTTCT GGAGACACCG GAAGCAGGCA 
GACCTAGACC TCGCCAAAGG TGATTTCGCA GCTGCTGCTG CCAACCTACA AACCTGCTTA 
TCCGTGCTGG GCCGGGCGCT GCCCACCTCC CGCCTGGACT TGGCCTGCAG CCTCTCCTGG 
AATGTGATCC GCTACAGCCT GCAGAAGCTG CGCCTGGTAC GCTGGTTACT CAAGAAGGTC 
TTCCAGCGCT GGCGGGCTAC TCCCGCCACT GCAGCTGGCT TTGAGGATGA GGCTAAGAGC 
AGCGCAAGGG ATGCGGCACT GGCCTACCAC AGGCTGCACC AGCTGCACAT CACAGGGAAG 
CTTCCGGCGG GATCTGCCTG TTCAGATGTG CACATGGCTC TGTGTGCTGT GAACCTGGCC 
GAGTGTGCGG AGGAGAAAAT CCTACCAAGC ACACTGATTG AGATCCACCT GACAGCGGCC 
ATGGGGCTCA AGACCCGCTG TGGAGGCAAG CTGGGCTTCT TGGCTAGCTA CTTCTTAAAT 
CGTGCCCAGA GTCTGTGTGG CCCAGAGCAT AGCACTGTCC CCGACTCCCT GCGCTGGCTA 
TGCCATCCCT TGGGCCAGAA GTTTTTCATG GAGCGAAGCT GGTCGATCAA GTCAGCAGCC 
AAGGAGAGCC TGTACTGCGC CCAGAGGAGC CCAGCTGACC CCATTGCCCA GGTACACCAG 
GCGTTCTGCA AAAACCTGCT AGAAAGAGCG GTGGAGTCCT TGGTGAAACC TCAGGCCAAG 
AAGAAGGCAG GCGACCAGGA AGAAGAGAGC TGTGAATTTT CCAGTGCTCT AGAGTATTTG 
AAATTACTTC ATTCTTTTGT GGACTCTGTG GGATTTGTGA CCTCACCATT CTCCAGCAGT 
TCCGTGCTCA GGTCGGCCCT TGGCCCCGAT GTCATCTGCC GGTGGTGGAC GTCCGCAGTC 
ACCATGGCCA TCAGCTGGCT CCAGGGAGAC GATGCAGCTG TGCGCTCTCG TTTTACTGAA 
GTAGAGCGGG TCCCCAAGGC CCTGGAAGTG ACCGAGAGTC CCTTGGTGAA GGCCGTCTTC 
TATACCTGTA GAGCCATGCA TGCCTCCCTC TCTGGGAAAG CTGACGGGCA GCAGAACTCC 
TTCTGTCACT GTGAGAGGGC CAGTGGTCAC CTGTGGAGCA GTCTCAACGT CAGCGGCACT 
ACTTCTGATC CTTCACTTAA CCATGTGATC CAGCTGTTCA CCTGTGACCT GCTACTGTCG 
CTGAGGACAG CACTCTGGCA AAAGCAGGCC AGTGCCAGCC AGCTCCTGGG TGAGACCTAC 
CATGCATCCG GCACTGAGCT GGCCGGCTTC CAGCGGGACC TGGGCAGCCT TCGAAGGCTG 
GCCCATAGCT TCCGCCCAGC CTACCGCAAG GTGTTCCTGC ATGAAGCCAC TGTGCGCCTG 
ATGGCAGGAG CCAGCCCTAC CCGTACACAC CAGCTGCTGG AGCATAGCCT ACGGCGGCGC 
CCCACTCAGA ACACCAAGCA TGGAGAGGTA GACACCTGGC CTGGCCAACG AGAGCGAGCT 
ACTGCCATCC TGCTGGCCTG CCGCCATCTT CCCCTCTCTT TCCTGTCTTC CCCGGGCCAG 
CGGGCAGTGC TGCTGGCTGA AGCTGCCCGC ACCCTGGAGA AGGTGGGTGA CCGCCGTTCC 
TGCAGTGACT GCCAGCAGAT GATTGTCAAG CTGGGCGGTG GCACTGCCAT CGCTGCCTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair.
Immunity51(2)241-257.e9(2019 08)
Kusnadi A,Park SH,Yuan R,Pannellini T,Giannopoulou E,Oliver D,Lu T,Park-Min KH,Ivashkiv LB

Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth.
Nature communications10(1)37(2019 01)
Guo M,Du Y,Gokey JJ,Ray S,Bell SM,Adam M,Sudha P,Perl AK,Deshmukh H,Potter SS,Whitsett JA,Xu Y

MicroRNA-98 regulates hepatic cholesterol metabolism via targeting sterol regulatory element-binding protein 2.
Biochemical and biophysical research communications504(2)422-426(2018 10)
Geng C,Dong T,Jin W,Yu B,Yin F,Peng F,Chen G,Ji C,Ding F

The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.
PLoS biology16(8)e2006443(2018 08)
Chan JP,Wong BH,Chin CF,Galam DLA,Foo JC,Wong LC,Ghosh S,Wenk MR,Cazenave-Gassiot A,Silver DL

Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.
Development (Cambridge, England)145(13)(2018 07)
Tsushima H,Tang YJ,Puviindran V,Hsu SC,Nadesan P,Yu C,Zhang H,Mirando AJ,Hilton MJ,Alman BA

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Srebf2 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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