| Gene Symbol | Sox18 |
| Entrez Gene ID | 20672 |
| Full Name | SRY (sex determining region Y)-box 18 |
| Synonyms | AI385749,Ra,Ragl |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Sox18 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Sox18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sox18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu15671 Clone ID Related Accession (Same CDS sequence) NM_009236.2 Accession Version NM_009236.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1134bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1572796800000 Organism Mus musculus(house mouse) Product transcription factor SOX-18 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK144281.1, BY141110.1 and AV167860.1. On Jan 26, 2007 this sequence version replaced NM_009236.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK144281.1, BC006612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGCAGAGAT CGCCGCCCGG CTACGGCGCA CAGGACGACC CGCCCTCCCG CCGCGACTGT
GCATGGGCCC CTGGAATCGG GGCCGCTGCT GAGGCGCGCG GCCTCCCTGT CACCAACGTC
TCGCCCACCT CGCCCGCCTC CCCGTCCAGC CTTCCGCGGA GCCCACCGCG CAGCCCCGAA
TCAGGGCGCT ATGGCTTTGG CCGCGGAGAG CGCCAAACTG CCGACGAGTT GCGCATTCGG
CGGCCCATGA ACGCCTTCAT GGTGTGGGCG AAGGACGAGC GCAAGCGACT GGCGCAACAA
AATCCGGATC TGCACAACGC AGTACTGAGC AAGATGCTGG GCAAAGCGTG GAAGGAGCTG
AACACGGCGG AGAAGCGGCC CTTCGTGGAA GAGGCCGAAC GGCTGCGTGT GCAGCACTTG
CGCGACCATC CCAACTACAA GTACCGGCCT CGCCGCAAAA AACAGGCGCG CAAGGTCCGG
AGGCTGGAGC CGGGCCTCTT GCTCCCGGGC CTCGTGCAGC CGTCTGCGCC GCCCGAGGCC
TTCGCTGCAG CGTCAGGGTC AGCTCGCTCC TTCCGCGAGC TACCCACTCT GGGTGCGGAG
TTCGATGGCT TGGGGCTACC CACGCCCGAG CGCTCGCCTC TGGACGGCCT GGAGCCTGGC
GAGGCCTCCT TCTTCCCACC GCCTTTGGCG CCCGAGGACT GCGCTCTGCG GGCTTTCCGG
GCACCCTATG CCCCTGAGCT GGCACGGGAC CCGAGCTTCT GCTACGGGGC GCCCCTGGCT
GAAGCGCTCA GGACAGCGCC GCCTGCCGCG CCACTCGCAG GTCTCTACTA TGGCACCCTG
GGCACTCCGG GCCCGTTTCC CAATCCTCTG TCACCACCAC CTGAGTCCCC GTCTCTTGAG
GGCACAGAGC AACTGGAGCC TACCGCCGAC CTTTGGGCCG ATGTGGACCT CACCGAATTT
GACCAGTATC TCAATTGCAG CCGGACTCGA CCGGATGCCA CTACACTCCC CTACCACGTG
GCACTGGCCA AACTAGGTCC GCGCGCCATG TCCTGTCCAG AAGAGAGCAG CCTCATTTCT
GCGCTGTCTG ATGCTAGCAG CGCGGTCTAT TACAGTGCTT GCATCTCAGG CTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_033262.2 CDS 120..1253 Translation 
Target ORF information:
RefSeq Version NM_009236.2 Organism Mus musculus(house mouse) Definition Mus musculus SRY (sex determining region Y)-box 18 (Sox18), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_009236.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGCAGAGAT CGCCGCCCGG CTACGGCGCA CAGGACGACC CGCCCTCCCG CCGCGACTGT
GCATGGGCCC CTGGAATCGG GGCCGCTGCT GAGGCGCGCG GCCTCCCTGT CACCAACGTC
TCGCCCACCT CGCCCGCCTC CCCGTCCAGC CTTCCGCGGA GCCCACCGCG CAGCCCCGAA
TCAGGGCGCT ATGGCTTTGG CCGCGGAGAG CGCCAAACTG CCGACGAGTT GCGCATTCGG
CGGCCCATGA ACGCCTTCAT GGTGTGGGCG AAGGACGAGC GCAAGCGACT GGCGCAACAA
AATCCGGATC TGCACAACGC AGTACTGAGC AAGATGCTGG GCAAAGCGTG GAAGGAGCTG
AACACGGCGG AGAAGCGGCC CTTCGTGGAA GAGGCCGAAC GGCTGCGTGT GCAGCACTTG
CGCGACCATC CCAACTACAA GTACCGGCCT CGCCGCAAAA AACAGGCGCG CAAGGTCCGG
AGGCTGGAGC CGGGCCTCTT GCTCCCGGGC CTCGTGCAGC CGTCTGCGCC GCCCGAGGCC
TTCGCTGCAG CGTCAGGGTC AGCTCGCTCC TTCCGCGAGC TACCCACTCT GGGTGCGGAG
TTCGATGGCT TGGGGCTACC CACGCCCGAG CGCTCGCCTC TGGACGGCCT GGAGCCTGGC
GAGGCCTCCT TCTTCCCACC GCCTTTGGCG CCCGAGGACT GCGCTCTGCG GGCTTTCCGG
GCACCCTATG CCCCTGAGCT GGCACGGGAC CCGAGCTTCT GCTACGGGGC GCCCCTGGCT
GAAGCGCTCA GGACAGCGCC GCCTGCCGCG CCACTCGCAG GTCTCTACTA TGGCACCCTG
GGCACTCCGG GCCCGTTTCC CAATCCTCTG TCACCACCAC CTGAGTCCCC GTCTCTTGAG
GGCACAGAGC AACTGGAGCC TACCGCCGAC CTTTGGGCCG ATGTGGACCT CACCGAATTT
GACCAGTATC TCAATTGCAG CCGGACTCGA CCGGATGCCA CTACACTCCC CTACCACGTG
GCACTGGCCA AACTAGGTCC GCGCGCCATG TCCTGTCCAG AAGAGAGCAG CCTCATTTCT
GCGCTGTCTG ATGCTAGCAG CGCGGTCTAT TACAGTGCTT GCATCTCAGG CTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma.
eLife8(2019 07)
Overman J,Fontaine F,Wylie-Sears J,Moustaqil M,Huang L,Meurer M,Chiang IK,Lesieur E,Patel J,Zuegg J,Pasquier E,Sierecki E,Gambin Y,Hamdan M,Khosrotehrani K,Andelfinger G,Bischoff J,Francois M
Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement.
Nature communications9(1)4877(2018 11)
Jia G,Preussner J,Chen X,Guenther S,Yuan X,Yekelchyk M,Kuenne C,Looso M,Zhou Y,Teichmann S,Braun T
Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor.
Nucleic acids research46(21)11381-11395(2018 11)
Moustaqil M,Fontaine F,Overman J,McCann A,Bailey TL,Rudolffi Soto P,Bhumkar A,Giles N,Hunter DJB,Gambin Y,Francois M,Sierecki E
Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.
Biology of reproduction99(3)578-589(2018 09)
Igarashi H,Uemura M,Hiramatsu R,Hiramatsu R,Segami S,Pattarapanawan M,Hirate Y,Yoshimura Y,Hashimoto H,Higashiyama H,Sumitomo H,Kurohmaru M,Saijoh Y,Suemizu H,Kanai-Azuma M,Kanai Y
SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity.
eLife7(2018 06)
Alonso-Martin S,Auradé F,Mademtzoglou D,Rochat A,Zammit PS,Relaix F
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