Polr2c cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Polr2c
Entrez Gene ID	20021
Full Name	polymerase (RNA) II (DNA directed) polypeptide C
Synonyms	33kDa,RPB3,Rpo2-3,mRBP31
General protein information	Preferred Names polymerase (RNA) II (DNA directed) polypeptide C Names DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II 33 kDa polypeptide DNA-directed RNA polymerase II subunit C RNA polymerase II 3 RNA polymerase II subunit 3 RNA polymerase II subunit B3 RPB31 RPB33
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 C5

mRNA and Protein(s)

mRNA	Protein	Name
NM_009090.5	NP_033116.2	DNA-directed RNA polymerase II subunit RPB3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	POLR2C	XP_001148305.1
Mus musculus (house mouse)	Polr2c	NP_033116.2
Drosophila melanogaster (fruit fly)	RpII33	NP_477419.1
Caenorhabditis elegans (roundworm)	rpb-3	NP_492361.2
Homo sapiens (human)	POLR2C	NP_116558.1
Macaca mulatta (Rhesus monkey)	POLR2C	XP_001098417.1
Bos taurus (cattle)	POLR2C	NP_001029384.1
Arabidopsis thaliana (thale cress)	NRPB3	NP_179145.1
Neurospora crassa	NCU01515	XP_956964.1
Oryza sativa (rice)	Os09g0110400	NP_001062572.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010321	XP_318245.2
Gallus gallus (chicken)	POLR2C	XP_414001.1
Arabidopsis thaliana (thale cress)	NRPE3B	NP_179142.1
Rattus norvegicus (Norway rat)	Polr2c	NP_001012491.1
Saccharomyces cerevisiae (baker's yeast)	RPB3	NP_012243.3
Eremothecium gossypii	AGOS_ADL120C	NP_983976.1
Magnaporthe oryzae (rice blast fungus)	MGG_03215	XP_003716764.1
Schizosaccharomyces pombe (fission yeast)	rpb3	NP_588324.1
Kluyveromyces lactis	KLLA0D16170g	XP_453773.1
Canis lupus familiaris (dog)	POLR2C	XP_535283.2
Danio rerio (zebrafish)	polr2c	NP_001161428.1
Xenopus tropicalis (tropical clawed frog)	polr2c	NP_989124.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
Alldred MJ, Lee SH, Petkova E, Ginsberg SD
The Journal of comparative neurology523(1)61-74(2015 Jan)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product.
Corbi N, Bruno T, De Angelis R, Di Padova M, Libri V, Di Certo MG, Spinardi L, Floridi A, Fanciulli M, Passananti C
Journal of cell science118(Pt 18)4253-60(2005 Sep)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

Protein interaction cloning in yeast of the mouse third largest RNA polymerase II subunit, mRPB31.
Korobko IV, Yamamoto K, Nogi Y, Muramatsu M
Gene185(1)1-4(1997 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Polr2c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Polr2c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu03502	NM_009090.5 Latest version!	Mus musculus polymerase (RNA) II (DNA directed) polypeptide C (Polr2c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Polr2c ( NM_009090.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033116.2 Mus musculus polymerase (RNA) II (DNA directed) polypeptide C (Polr2c), mRNA.

Price & Availability↑

CloneID	OMu03502
Clone ID Related Accession (Same CDS sequence)	NM_009090.5
Accession Version	NM_009090.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 828bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	DNA-directed RNA polymerase II subunit RPB3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC129606.4. On Jul 11, 2009 this sequence version replaced NM_009090.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC099548.1, AK160053.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGTACG CCAACCAGCC AACAGTGCGG ATCACGGAAC TCACCGAAGA GAACGTCAAG 
TTCATTATCG AGAACACGGA CCTGGCGGTG GCCAATTCCA TTCGGAGGGT CTTCATCGCA 
GAGGTGCCCA TAATAGCCAT CGACTGGGTT CAGATTGACG CCAACTCCTC GGTCCTTCAT 
GATGAATTCA TCGCGCACAG GCTTGGTTTA ATCCCCCTCA CTAGTGATGA CATTGTGGAC 
AAGCTGCAGT ACTCCCGGGA CTGCACATGT GAAGAGTTCT GCCCTGAGTG TTCTGTGGAG 
TTCACTCTCG ATGTGAGGTG CAATGAAGAC CAGACGCGCC ATGTCACCTC CCGAGATCTC 
ATCTCCAACA GCCCCCGGGT TATTCCGGTG ACATCTCGGA ACCGGGATAA CGACCCTAAT 
GACTATGTGG AGCAGGATGA CATCCTTATT GTCAAGCTGA GGAAGGGGCA GGAGCTGAGA 
CTTCGAGCCT ATGCCAAGAA GGGCTTTGGC AAGGAACATG CCAAGTGGAA CCCTACTGCG 
GGGGTAGCTT TTGAATACGA TCCAGACAAC GCACTTAGGC ATACAGTGTA TCCCAAGCCT 
GAGGAATGGC CCAAGAGTGA GTATTCCGAG CTGGATGAGG ATGAGTCGCA GGCTCCCTAC 
GACCCCAACG GCAAGCCAGA GAGGTTTTAC TACAATGTGG AGTCGTGTGG CTCACTGCGC 
CCTGAAACCA TTGTCCTCTC AGCCCTGTCG GGGCTAAAGA AGAAGCTGAG TGATTTACAG 
ACTCAGTTAA GCCATGAGAT CCAGAGTGAC GTGCTCACCA TAAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033116.2
CDS	107..934
Translation	MPYANQPTVRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN

Target ORF information:

RefSeq Version	NM_009090.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus polymerase (RNA) II (DNA directed) polypeptide C (Polr2c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009090.5

ORF Insert Sequence:

ATGCCGTACG CCAACCAGCC AACAGTGCGG ATCACGGAAC TCACCGAAGA GAACGTCAAG 
TTCATTATCG AGAACACGGA CCTGGCGGTG GCCAATTCCA TTCGGAGGGT CTTCATCGCA 
GAGGTGCCCA TAATAGCCAT CGACTGGGTT CAGATTGACG CCAACTCCTC GGTCCTTCAT 
GATGAATTCA TCGCGCACAG GCTTGGTTTA ATCCCCCTCA CTAGTGATGA CATTGTGGAC 
AAGCTGCAGT ACTCCCGGGA CTGCACATGT GAAGAGTTCT GCCCTGAGTG TTCTGTGGAG 
TTCACTCTCG ATGTGAGGTG CAATGAAGAC CAGACGCGCC ATGTCACCTC CCGAGATCTC 
ATCTCCAACA GCCCCCGGGT TATTCCGGTG ACATCTCGGA ACCGGGATAA CGACCCTAAT 
GACTATGTGG AGCAGGATGA CATCCTTATT GTCAAGCTGA GGAAGGGGCA GGAGCTGAGA 
CTTCGAGCCT ATGCCAAGAA GGGCTTTGGC AAGGAACATG CCAAGTGGAA CCCTACTGCG 
GGGGTAGCTT TTGAATACGA TCCAGACAAC GCACTTAGGC ATACAGTGTA TCCCAAGCCT 
GAGGAATGGC CCAAGAGTGA GTATTCCGAG CTGGATGAGG ATGAGTCGCA GGCTCCCTAC 
GACCCCAACG GCAAGCCAGA GAGGTTTTAC TACAATGTGG AGTCGTGTGG CTCACTGCGC 
CCTGAAACCA TTGTCCTCTC AGCCCTGTCG GGGCTAAAGA AGAAGCTGAG TGATTTACAG 
ACTCAGTTAA GCCATGAGAT CCAGAGTGAC GTGCTCACCA TAAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
The Journal of comparative neurology523(1)61-74(2015 Jan)
Alldred MJ,Lee SH,Petkova E,Ginsberg SD

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product.
Journal of cell science118(Pt 18)4253-60(2005 Sep)
Corbi N,Bruno T,De Angelis R,Di Padova M,Libri V,Di Certo MG,Spinardi L,Floridi A,Fanciulli M,Passananti C

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

Protein interaction cloning in yeast of the mouse third largest RNA polymerase II subunit, mRPB31.
Gene185(1)1-4(1997 Jan)
Korobko IV,Yamamoto K,Nogi Y,Muramatsu M

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Polr2c cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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