Por cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Por
Entrez Gene ID	18984
Full Name	P450 (cytochrome) oxidoreductase
Synonyms	4933424M13Rik,CPR,CYPOR,P450R
General protein information	Preferred Names P450 (cytochrome) oxidoreductase Names NADPH--cytochrome P450 reductase NADH cytochrome P450 oxydoreductase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 G2\|5 75.34 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006504399.1	XP_006504462.1	NADPH--cytochrome P450 reductase isoform X1
XM_006504398.1	XP_006504461.1	NADPH--cytochrome P450 reductase isoform X1
NM_008898.2	NP_032924.1	NADPH--cytochrome P450 reductase

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	POR	NP_001171276.1
Gallus gallus (chicken)	POR	NP_001182725.1
Kluyveromyces lactis	KLLA0D08712g	XP_453451.1
Oryza sativa (rice)	Os09g0558900	NP_001063914.1
Homo sapiens (human)	POR	NP_000932.3
Pan troglodytes (chimpanzee)	POR	XP_001155755.2
Macaca mulatta (Rhesus monkey)	POR	XP_001109664.1
Drosophila melanogaster (fruit fly)	Cpr	NP_001260128.1
Caenorhabditis elegans (roundworm)	emb-8	NP_498103.1
Oryza sativa (rice)	Os08g0243500	NP_001061346.1
Schizosaccharomyces pombe (fission yeast)	ccr1	NP_596046.1
Eremothecium gossypii	AGOS_AAL121C	NP_982421.1
Magnaporthe oryzae (rice blast fungus)	MGG_07117	XP_003715306.1
Rattus norvegicus (Norway rat)	Por	NP_113764.1
Danio rerio (zebrafish)	por	NP_001030154.1
Bos taurus (cattle)	POR	NP_001030467.1
Mus musculus (house mouse)	Por	NP_032924.1
Saccharomyces cerevisiae (baker's yeast)	NCP1	NP_011908.1
Arabidopsis thaliana (thale cress)	ATR2	NP_849472.2
Neurospora crassa	NCU09741	XP_964443.1
Xenopus tropicalis (tropical clawed frog)	por	XP_002933864.1

Gene Ontology
Bibliography

Related articles in PubMed

Application of hepatic cytochrome b
Reed L, Indra R, Mrizova I, Moserova M, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM
Toxicology and applied pharmacology36664-74(2019 03)

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.
Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD
Nature communications8(1)39(2017 06)

Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays.
Rezende F, Prior KK, Löwe O, Wittig I, Strecker V, Moll F, Helfinger V, Schnütgen F, Kurrle N, Wempe F, Walter M, Zukunft S, Luck B, Fleming I, Weissmann N, Brandes RP, Schröder K
Free radical biology & medicine10257-66(2017 01)

Oscillating primary transcripts harbor miRNAs with circadian functions.
Wang H, Fan Z, Zhao M, Li J, Lu M, Liu W, Ying H, Liu M, Yan J
Scientific reports621598(2016 Feb)

Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability.
Henderson CJ, McLaughlin LA, Osuna-Cabello M, Taylor M, Gilbert I, McLaren AW, Wolf CR
The Biochemical journal465(3)479-88(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Por gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Por cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19095	NM_008898.2 Latest version!	Mus musculus P450 (cytochrome) oxidoreductase (Por), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu19095	XM_006504398.1 Latest version!	Mus musculus P450 (cytochrome) oxidoreductase (Por), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu19095	XM_006504399.1 Latest version!	Mus musculus P450 (cytochrome) oxidoreductase (Por), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Por ( NM_008898.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032924.1 Mus musculus P450 (cytochrome) oxidoreductase (Por), mRNA.

Price & Availability↑

CloneID	OMu19095
Clone ID Related Accession (Same CDS sequence)	XM_006504399.1 , XM_006504398.1 , NM_008898.2
Accession Version	NM_008898.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577462400000
Organism	Mus musculus(house mouse)
Product	NADPH--cytochrome P450 reductase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC083948.3. On May 5, 2015 this sequence version replaced NM_008898.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031463.1, D17571.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGACT CTCACGAAGA CACCAGTGCC ACAGTGCCTG AGGCAGTGGC TGAAGAAGTG 
TCTCTATTCA GCACAACGGA CATTGTTCTG TTTTCTCTCA TCGTGGGGGT CCTGACCTAC 
TGGTTCATCT TTAAAAAGAA GAAAGAAGAG ATACCGGAGT TCAGCAAGAT CCAGACAACG 
GCCCCACCTG TCAAAGAGAG CAGCTTCGTG GAAAAGATGA AGAAAACGGG AAGGAACATT 
ATTGTATTCT ATGGCTCCCA GACGGGAACC GCGGAGGAGT TTGCCAACCG GCTGTCCAAG 
GATGCCCACC GCTATGGGAT GCGGGGCATG TCTGCAGACC CTGAAGAGTA TGACTTGGCC 
GACCTGAGCA GCCTGCCTGA GATCGACAAG TCCCTGGTAG TCTTCTGCAT GGCCACATAC 
GGAGAAGGCG ACCCCACCGA CAACGCGCAG GACTTCTATG ATTGGCTGCA GGAGACTGAC 
GTGGACCTCA CGGGTGTCAA GTTTGCTGTG TTTGGTCTCG GGAACAAGAC CTATGAGCAC 
TTCAACGCCA TGGGCAAGTA TGTGGACCAG CGGCTGGAGC AGCTTGGCGC CCAGCGAATC 
TTTGAGTTGG GCCTTGGTGA TGACGACGGG AACTTGGAAG AGGATTTCAT CACATGGAGG 
GAGCAGTTCT GGCCAGCTGT GTGCGAGTTC TTCGGGGTGG AAGCCACTGG GGAGGAGTCG 
AGCATCCGCC AGTACGAGCT CGTGGTCCAC GAAGACATGG ACACAGCCAA GGTGTACACG 
GGTGAGATGG GCCGTCTGAA GAGCTACGAG AACCAGAAAC CCCCCTTCGA TGCCAAGAAT 
CCATTCCTGG CTGCTGTCAC CACGAACCGG AAGCTGAACC AAGGCACTGA GAGGCATCTA 
ATGCACCTGG AATTGGACAT CTCAGACTCC AAGATCAGGT ATGAATCTGG AGATCACGTG 
GCTGTGTACC CAGCCAACGA CTCCACCCTG GTCAACCAGA TTGGGGAGAT CCTGGGGGCT 
GACCTGGATG TCATCATGTC TCTAAACAAT CTCGATGAGG AGTCGAATAA GAAGCATCCG 
TTCCCCTGCC CCACCACCTA CCGCACGGCC CTCACCTACT ACCTGGACAT CACTAACCCG 
CCACGAACCA ACGTGCTCTA CGAGCTGGCC CAGTACGCCT CAGAGCCCTC GGAGCAGGAA 
CACCTGCACA AGATGGCGTC CTCCTCCGGC GAGGGCAAGG AGCTGTACCT GAGCTGGGTG 
GTGGAGGCCC GGAGGCACAT CCTAGCCATT CTCCAAGACT ACCCGTCCCT GCGGCCACCC 
ATCGACCACC TGTGCGAGCT CCTCCCGAGG CTGCAGGCCC GCTACTATTC CATTGCCTCG 
TCGTCTAAGG TCCACCCCAA CTCCGTGCAC ATCTGCGCCG TGGCTGTGGA GTATGAAGCG 
AAGTCTGGAC GAGTGAACAA GGGGGTGGCC ACCAGCTGGC TTCGGACCAA GGAACCAGCA 
GGAGAGAATG GCCGCCGGGC CCTGGTCCCC ATGTTCGTCC GCAAGTCCCA GTTCCGCTTG 
CCTTTCAAGC CCACCACACC TGTTATCATG GTGGGCCCCG GCACTGGGGT TGCCCCTTTC 
ATGGGCTTCA TCCAGGAGCG GGCTTGGCTT CGAGAGCAAG GCAAGGAGGT CGGAGAGACG 
CTGCTCTACT ACGGCTGCCG GCGCTCGGAT GAGGACTATC TGTACCGCGA GGAGCTGGCG 
CGCTTCCACA AGGACGGCGC CCTCACGCAG CTTAATGTGG CCTTTTCCCG TGAGCAGGCC 
CACAAGGTCT ATGTTCAGCA CCTGCTCAAG AGGGACAAAG AGCACCTGTG GAAGCTGATC 
CACGAAGGTG GTGCCCACAT CTATGTCTGC GGGGATGCTC GAAATATGGC CAAAGATGTG 
CAGAACACAT TCTATGACAT CGTGGCCGAG TTTGGGCCCA TGGAGCACAC CCAGGCTGTG 
GACTATGTTA AGAAGCTCAT GACCAAGGGC CGCTACTCGC TGGATGTATG GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032924.1
CDS	122..2158
Translation	MGDSHEDTSATVPEAVAEEVSLFSTTDIVLFSLIVGVLTYWFIFKKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDTAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSTLVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRTKEPAGENGRRALVPMFVRKSQFRLPFKPTTPVIMVGPGTGVAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDKEHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS

Target ORF information:

RefSeq Version	NM_008898.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus P450 (cytochrome) oxidoreductase (Por), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008898.2

ORF Insert Sequence:

ATGGGGGACT CTCACGAAGA CACCAGTGCC ACAGTGCCTG AGGCAGTGGC TGAAGAAGTG 
TCTCTATTCA GCACAACGGA CATTGTTCTG TTTTCTCTCA TCGTGGGGGT CCTGACCTAC 
TGGTTCATCT TTAAAAAGAA GAAAGAAGAG ATACCGGAGT TCAGCAAGAT CCAGACAACG 
GCCCCACCTG TCAAAGAGAG CAGCTTCGTG GAAAAGATGA AGAAAACGGG AAGGAACATT 
ATTGTATTCT ATGGCTCCCA GACGGGAACC GCGGAGGAGT TTGCCAACCG GCTGTCCAAG 
GATGCCCACC GCTATGGGAT GCGGGGCATG TCTGCAGACC CTGAAGAGTA TGACTTGGCC 
GACCTGAGCA GCCTGCCTGA GATCGACAAG TCCCTGGTAG TCTTCTGCAT GGCCACATAC 
GGAGAAGGCG ACCCCACCGA CAACGCGCAG GACTTCTATG ATTGGCTGCA GGAGACTGAC 
GTGGACCTCA CGGGTGTCAA GTTTGCTGTG TTTGGTCTCG GGAACAAGAC CTATGAGCAC 
TTCAACGCCA TGGGCAAGTA TGTGGACCAG CGGCTGGAGC AGCTTGGCGC CCAGCGAATC 
TTTGAGTTGG GCCTTGGTGA TGACGACGGG AACTTGGAAG AGGATTTCAT CACATGGAGG 
GAGCAGTTCT GGCCAGCTGT GTGCGAGTTC TTCGGGGTGG AAGCCACTGG GGAGGAGTCG 
AGCATCCGCC AGTACGAGCT CGTGGTCCAC GAAGACATGG ACACAGCCAA GGTGTACACG 
GGTGAGATGG GCCGTCTGAA GAGCTACGAG AACCAGAAAC CCCCCTTCGA TGCCAAGAAT 
CCATTCCTGG CTGCTGTCAC CACGAACCGG AAGCTGAACC AAGGCACTGA GAGGCATCTA 
ATGCACCTGG AATTGGACAT CTCAGACTCC AAGATCAGGT ATGAATCTGG AGATCACGTG 
GCTGTGTACC CAGCCAACGA CTCCACCCTG GTCAACCAGA TTGGGGAGAT CCTGGGGGCT 
GACCTGGATG TCATCATGTC TCTAAACAAT CTCGATGAGG AGTCGAATAA GAAGCATCCG 
TTCCCCTGCC CCACCACCTA CCGCACGGCC CTCACCTACT ACCTGGACAT CACTAACCCG 
CCACGAACCA ACGTGCTCTA CGAGCTGGCC CAGTACGCCT CAGAGCCCTC GGAGCAGGAA 
CACCTGCACA AGATGGCGTC CTCCTCCGGC GAGGGCAAGG AGCTGTACCT GAGCTGGGTG 
GTGGAGGCCC GGAGGCACAT CCTAGCCATT CTCCAAGACT ACCCGTCCCT GCGGCCACCC 
ATCGACCACC TGTGCGAGCT CCTCCCGAGG CTGCAGGCCC GCTACTATTC CATTGCCTCG 
TCGTCTAAGG TCCACCCCAA CTCCGTGCAC ATCTGCGCCG TGGCTGTGGA GTATGAAGCG 
AAGTCTGGAC GAGTGAACAA GGGGGTGGCC ACCAGCTGGC TTCGGACCAA GGAACCAGCA 
GGAGAGAATG GCCGCCGGGC CCTGGTCCCC ATGTTCGTCC GCAAGTCCCA GTTCCGCTTG 
CCTTTCAAGC CCACCACACC TGTTATCATG GTGGGCCCCG GCACTGGGGT TGCCCCTTTC 
ATGGGCTTCA TCCAGGAGCG GGCTTGGCTT CGAGAGCAAG GCAAGGAGGT CGGAGAGACG 
CTGCTCTACT ACGGCTGCCG GCGCTCGGAT GAGGACTATC TGTACCGCGA GGAGCTGGCG 
CGCTTCCACA AGGACGGCGC CCTCACGCAG CTTAATGTGG CCTTTTCCCG TGAGCAGGCC 
CACAAGGTCT ATGTTCAGCA CCTGCTCAAG AGGGACAAAG AGCACCTGTG GAAGCTGATC 
CACGAAGGTG GTGCCCACAT CTATGTCTGC GGGGATGCTC GAAATATGGC CAAAGATGTG 
CAGAACACAT TCTATGACAT CGTGGCCGAG TTTGGGCCCA TGGAGCACAC CCAGGCTGTG 
GACTATGTTA AGAAGCTCAT GACCAAGGGC CGCTACTCGC TGGATGTATG GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Por ( XM_006504399.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504462.1 Mus musculus P450 (cytochrome) oxidoreductase (Por), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu19095
Clone ID Related Accession (Same CDS sequence)	XM_006504399.1 , XM_006504398.1 , NM_008898.2
Accession Version	XM_006504399.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	NADPH--cytochrome P450 reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGACT CTCACGAAGA CACCAGTGCC ACAGTGCCTG AGGCAGTGGC TGAAGAAGTG 
TCTCTATTCA GCACAACGGA CATTGTTCTG TTTTCTCTCA TCGTGGGGGT CCTGACCTAC 
TGGTTCATCT TTAAAAAGAA GAAAGAAGAG ATACCGGAGT TCAGCAAGAT CCAGACAACG 
GCCCCACCTG TCAAAGAGAG CAGCTTCGTG GAAAAGATGA AGAAAACGGG AAGGAACATT 
ATTGTATTCT ATGGCTCCCA GACGGGAACC GCGGAGGAGT TTGCCAACCG GCTGTCCAAG 
GATGCCCACC GCTATGGGAT GCGGGGCATG TCTGCAGACC CTGAAGAGTA TGACTTGGCC 
GACCTGAGCA GCCTGCCTGA GATCGACAAG TCCCTGGTAG TCTTCTGCAT GGCCACATAC 
GGAGAAGGCG ACCCCACCGA CAACGCGCAG GACTTCTATG ATTGGCTGCA GGAGACTGAC 
GTGGACCTCA CGGGTGTCAA GTTTGCTGTG TTTGGTCTCG GGAACAAGAC CTATGAGCAC 
TTCAACGCCA TGGGCAAGTA TGTGGACCAG CGGCTGGAGC AGCTTGGCGC CCAGCGAATC 
TTTGAGTTGG GCCTTGGTGA TGACGACGGG AACTTGGAAG AGGATTTCAT CACATGGAGG 
GAGCAGTTCT GGCCAGCTGT GTGCGAGTTC TTCGGGGTGG AAGCCACTGG GGAGGAGTCG 
AGCATCCGCC AGTACGAGCT CGTGGTCCAC GAAGACATGG ACACAGCCAA GGTGTACACG 
GGTGAGATGG GCCGTCTGAA GAGCTACGAG AACCAGAAAC CCCCCTTCGA TGCCAAGAAT 
CCATTCCTGG CTGCTGTCAC CACGAACCGG AAGCTGAACC AAGGCACTGA GAGGCATCTA 
ATGCACCTGG AATTGGACAT CTCAGACTCC AAGATCAGGT ATGAATCTGG AGATCACGTG 
GCTGTGTACC CAGCCAACGA CTCCACCCTG GTCAACCAGA TTGGGGAGAT CCTGGGGGCT 
GACCTGGATG TCATCATGTC TCTAAACAAT CTCGATGAGG AGTCGAATAA GAAGCATCCG 
TTCCCCTGCC CCACCACCTA CCGCACGGCC CTCACCTACT ACCTGGACAT CACTAACCCG 
CCACGAACCA ACGTGCTCTA CGAGCTGGCC CAGTACGCCT CAGAGCCCTC GGAGCAGGAA 
CACCTGCACA AGATGGCGTC CTCCTCCGGC GAGGGCAAGG AGCTGTACCT GAGCTGGGTG 
GTGGAGGCCC GGAGGCACAT CCTAGCCATT CTCCAAGACT ACCCGTCCCT GCGGCCACCC 
ATCGACCACC TGTGCGAGCT CCTCCCGAGG CTGCAGGCCC GCTACTATTC CATTGCCTCG 
TCGTCTAAGG TCCACCCCAA CTCCGTGCAC ATCTGCGCCG TGGCTGTGGA GTATGAAGCG 
AAGTCTGGAC GAGTGAACAA GGGGGTGGCC ACCAGCTGGC TTCGGACCAA GGAACCAGCA 
GGAGAGAATG GCCGCCGGGC CCTGGTCCCC ATGTTCGTCC GCAAGTCCCA GTTCCGCTTG 
CCTTTCAAGC CCACCACACC TGTTATCATG GTGGGCCCCG GCACTGGGGT TGCCCCTTTC 
ATGGGCTTCA TCCAGGAGCG GGCTTGGCTT CGAGAGCAAG GCAAGGAGGT CGGAGAGACG 
CTGCTCTACT ACGGCTGCCG GCGCTCGGAT GAGGACTATC TGTACCGCGA GGAGCTGGCG 
CGCTTCCACA AGGACGGCGC CCTCACGCAG CTTAATGTGG CCTTTTCCCG TGAGCAGGCC 
CACAAGGTCT ATGTTCAGCA CCTGCTCAAG AGGGACAAAG AGCACCTGTG GAAGCTGATC 
CACGAAGGTG GTGCCCACAT CTATGTCTGC GGGGATGCTC GAAATATGGC CAAAGATGTG 
CAGAACACAT TCTATGACAT CGTGGCCGAG TTTGGGCCCA TGGAGCACAC CCAGGCTGTG 
GACTATGTTA AGAAGCTCAT GACCAAGGGC CGCTACTCGC TGGATGTATG GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504462.1
CDS	91..2127
Translation	MGDSHEDTSATVPEAVAEEVSLFSTTDIVLFSLIVGVLTYWFIFKKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDTAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSTLVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRTKEPAGENGRRALVPMFVRKSQFRLPFKPTTPVIMVGPGTGVAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDKEHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS

Target ORF information:

RefSeq Version	XM_006504399.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus P450 (cytochrome) oxidoreductase (Por), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504399.1

ORF Insert Sequence:

ATGGGGGACT CTCACGAAGA CACCAGTGCC ACAGTGCCTG AGGCAGTGGC TGAAGAAGTG 
TCTCTATTCA GCACAACGGA CATTGTTCTG TTTTCTCTCA TCGTGGGGGT CCTGACCTAC 
TGGTTCATCT TTAAAAAGAA GAAAGAAGAG ATACCGGAGT TCAGCAAGAT CCAGACAACG 
GCCCCACCTG TCAAAGAGAG CAGCTTCGTG GAAAAGATGA AGAAAACGGG AAGGAACATT 
ATTGTATTCT ATGGCTCCCA GACGGGAACC GCGGAGGAGT TTGCCAACCG GCTGTCCAAG 
GATGCCCACC GCTATGGGAT GCGGGGCATG TCTGCAGACC CTGAAGAGTA TGACTTGGCC 
GACCTGAGCA GCCTGCCTGA GATCGACAAG TCCCTGGTAG TCTTCTGCAT GGCCACATAC 
GGAGAAGGCG ACCCCACCGA CAACGCGCAG GACTTCTATG ATTGGCTGCA GGAGACTGAC 
GTGGACCTCA CGGGTGTCAA GTTTGCTGTG TTTGGTCTCG GGAACAAGAC CTATGAGCAC 
TTCAACGCCA TGGGCAAGTA TGTGGACCAG CGGCTGGAGC AGCTTGGCGC CCAGCGAATC 
TTTGAGTTGG GCCTTGGTGA TGACGACGGG AACTTGGAAG AGGATTTCAT CACATGGAGG 
GAGCAGTTCT GGCCAGCTGT GTGCGAGTTC TTCGGGGTGG AAGCCACTGG GGAGGAGTCG 
AGCATCCGCC AGTACGAGCT CGTGGTCCAC GAAGACATGG ACACAGCCAA GGTGTACACG 
GGTGAGATGG GCCGTCTGAA GAGCTACGAG AACCAGAAAC CCCCCTTCGA TGCCAAGAAT 
CCATTCCTGG CTGCTGTCAC CACGAACCGG AAGCTGAACC AAGGCACTGA GAGGCATCTA 
ATGCACCTGG AATTGGACAT CTCAGACTCC AAGATCAGGT ATGAATCTGG AGATCACGTG 
GCTGTGTACC CAGCCAACGA CTCCACCCTG GTCAACCAGA TTGGGGAGAT CCTGGGGGCT 
GACCTGGATG TCATCATGTC TCTAAACAAT CTCGATGAGG AGTCGAATAA GAAGCATCCG 
TTCCCCTGCC CCACCACCTA CCGCACGGCC CTCACCTACT ACCTGGACAT CACTAACCCG 
CCACGAACCA ACGTGCTCTA CGAGCTGGCC CAGTACGCCT CAGAGCCCTC GGAGCAGGAA 
CACCTGCACA AGATGGCGTC CTCCTCCGGC GAGGGCAAGG AGCTGTACCT GAGCTGGGTG 
GTGGAGGCCC GGAGGCACAT CCTAGCCATT CTCCAAGACT ACCCGTCCCT GCGGCCACCC 
ATCGACCACC TGTGCGAGCT CCTCCCGAGG CTGCAGGCCC GCTACTATTC CATTGCCTCG 
TCGTCTAAGG TCCACCCCAA CTCCGTGCAC ATCTGCGCCG TGGCTGTGGA GTATGAAGCG 
AAGTCTGGAC GAGTGAACAA GGGGGTGGCC ACCAGCTGGC TTCGGACCAA GGAACCAGCA 
GGAGAGAATG GCCGCCGGGC CCTGGTCCCC ATGTTCGTCC GCAAGTCCCA GTTCCGCTTG 
CCTTTCAAGC CCACCACACC TGTTATCATG GTGGGCCCCG GCACTGGGGT TGCCCCTTTC 
ATGGGCTTCA TCCAGGAGCG GGCTTGGCTT CGAGAGCAAG GCAAGGAGGT CGGAGAGACG 
CTGCTCTACT ACGGCTGCCG GCGCTCGGAT GAGGACTATC TGTACCGCGA GGAGCTGGCG 
CGCTTCCACA AGGACGGCGC CCTCACGCAG CTTAATGTGG CCTTTTCCCG TGAGCAGGCC 
CACAAGGTCT ATGTTCAGCA CCTGCTCAAG AGGGACAAAG AGCACCTGTG GAAGCTGATC 
CACGAAGGTG GTGCCCACAT CTATGTCTGC GGGGATGCTC GAAATATGGC CAAAGATGTG 
CAGAACACAT TCTATGACAT CGTGGCCGAG TTTGGGCCCA TGGAGCACAC CCAGGCTGTG 
GACTATGTTA AGAAGCTCAT GACCAAGGGC CGCTACTCGC TGGATGTATG GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Por ( XM_006504398.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504461.1 Mus musculus P450 (cytochrome) oxidoreductase (Por), transcript variant X2, mRNA.

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CloneID	OMu19095
Clone ID Related Accession (Same CDS sequence)	XM_006504399.1 , XM_006504398.1 , NM_008898.2
Accession Version	XM_006504398.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	NADPH--cytochrome P450 reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGACT CTCACGAAGA CACCAGTGCC ACAGTGCCTG AGGCAGTGGC TGAAGAAGTG 
TCTCTATTCA GCACAACGGA CATTGTTCTG TTTTCTCTCA TCGTGGGGGT CCTGACCTAC 
TGGTTCATCT TTAAAAAGAA GAAAGAAGAG ATACCGGAGT TCAGCAAGAT CCAGACAACG 
GCCCCACCTG TCAAAGAGAG CAGCTTCGTG GAAAAGATGA AGAAAACGGG AAGGAACATT 
ATTGTATTCT ATGGCTCCCA GACGGGAACC GCGGAGGAGT TTGCCAACCG GCTGTCCAAG 
GATGCCCACC GCTATGGGAT GCGGGGCATG TCTGCAGACC CTGAAGAGTA TGACTTGGCC 
GACCTGAGCA GCCTGCCTGA GATCGACAAG TCCCTGGTAG TCTTCTGCAT GGCCACATAC 
GGAGAAGGCG ACCCCACCGA CAACGCGCAG GACTTCTATG ATTGGCTGCA GGAGACTGAC 
GTGGACCTCA CGGGTGTCAA GTTTGCTGTG TTTGGTCTCG GGAACAAGAC CTATGAGCAC 
TTCAACGCCA TGGGCAAGTA TGTGGACCAG CGGCTGGAGC AGCTTGGCGC CCAGCGAATC 
TTTGAGTTGG GCCTTGGTGA TGACGACGGG AACTTGGAAG AGGATTTCAT CACATGGAGG 
GAGCAGTTCT GGCCAGCTGT GTGCGAGTTC TTCGGGGTGG AAGCCACTGG GGAGGAGTCG 
AGCATCCGCC AGTACGAGCT CGTGGTCCAC GAAGACATGG ACACAGCCAA GGTGTACACG 
GGTGAGATGG GCCGTCTGAA GAGCTACGAG AACCAGAAAC CCCCCTTCGA TGCCAAGAAT 
CCATTCCTGG CTGCTGTCAC CACGAACCGG AAGCTGAACC AAGGCACTGA GAGGCATCTA 
ATGCACCTGG AATTGGACAT CTCAGACTCC AAGATCAGGT ATGAATCTGG AGATCACGTG 
GCTGTGTACC CAGCCAACGA CTCCACCCTG GTCAACCAGA TTGGGGAGAT CCTGGGGGCT 
GACCTGGATG TCATCATGTC TCTAAACAAT CTCGATGAGG AGTCGAATAA GAAGCATCCG 
TTCCCCTGCC CCACCACCTA CCGCACGGCC CTCACCTACT ACCTGGACAT CACTAACCCG 
CCACGAACCA ACGTGCTCTA CGAGCTGGCC CAGTACGCCT CAGAGCCCTC GGAGCAGGAA 
CACCTGCACA AGATGGCGTC CTCCTCCGGC GAGGGCAAGG AGCTGTACCT GAGCTGGGTG 
GTGGAGGCCC GGAGGCACAT CCTAGCCATT CTCCAAGACT ACCCGTCCCT GCGGCCACCC 
ATCGACCACC TGTGCGAGCT CCTCCCGAGG CTGCAGGCCC GCTACTATTC CATTGCCTCG 
TCGTCTAAGG TCCACCCCAA CTCCGTGCAC ATCTGCGCCG TGGCTGTGGA GTATGAAGCG 
AAGTCTGGAC GAGTGAACAA GGGGGTGGCC ACCAGCTGGC TTCGGACCAA GGAACCAGCA 
GGAGAGAATG GCCGCCGGGC CCTGGTCCCC ATGTTCGTCC GCAAGTCCCA GTTCCGCTTG 
CCTTTCAAGC CCACCACACC TGTTATCATG GTGGGCCCCG GCACTGGGGT TGCCCCTTTC 
ATGGGCTTCA TCCAGGAGCG GGCTTGGCTT CGAGAGCAAG GCAAGGAGGT CGGAGAGACG 
CTGCTCTACT ACGGCTGCCG GCGCTCGGAT GAGGACTATC TGTACCGCGA GGAGCTGGCG 
CGCTTCCACA AGGACGGCGC CCTCACGCAG CTTAATGTGG CCTTTTCCCG TGAGCAGGCC 
CACAAGGTCT ATGTTCAGCA CCTGCTCAAG AGGGACAAAG AGCACCTGTG GAAGCTGATC 
CACGAAGGTG GTGCCCACAT CTATGTCTGC GGGGATGCTC GAAATATGGC CAAAGATGTG 
CAGAACACAT TCTATGACAT CGTGGCCGAG TTTGGGCCCA TGGAGCACAC CCAGGCTGTG 
GACTATGTTA AGAAGCTCAT GACCAAGGGC CGCTACTCGC TGGATGTATG GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504461.1
CDS	86..2122
Translation	MGDSHEDTSATVPEAVAEEVSLFSTTDIVLFSLIVGVLTYWFIFKKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDTAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSTLVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRTKEPAGENGRRALVPMFVRKSQFRLPFKPTTPVIMVGPGTGVAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDKEHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS

Target ORF information:

RefSeq Version	XM_006504398.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus P450 (cytochrome) oxidoreductase (Por), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504398.1

ORF Insert Sequence:

ATGGGGGACT CTCACGAAGA CACCAGTGCC ACAGTGCCTG AGGCAGTGGC TGAAGAAGTG 
TCTCTATTCA GCACAACGGA CATTGTTCTG TTTTCTCTCA TCGTGGGGGT CCTGACCTAC 
TGGTTCATCT TTAAAAAGAA GAAAGAAGAG ATACCGGAGT TCAGCAAGAT CCAGACAACG 
GCCCCACCTG TCAAAGAGAG CAGCTTCGTG GAAAAGATGA AGAAAACGGG AAGGAACATT 
ATTGTATTCT ATGGCTCCCA GACGGGAACC GCGGAGGAGT TTGCCAACCG GCTGTCCAAG 
GATGCCCACC GCTATGGGAT GCGGGGCATG TCTGCAGACC CTGAAGAGTA TGACTTGGCC 
GACCTGAGCA GCCTGCCTGA GATCGACAAG TCCCTGGTAG TCTTCTGCAT GGCCACATAC 
GGAGAAGGCG ACCCCACCGA CAACGCGCAG GACTTCTATG ATTGGCTGCA GGAGACTGAC 
GTGGACCTCA CGGGTGTCAA GTTTGCTGTG TTTGGTCTCG GGAACAAGAC CTATGAGCAC 
TTCAACGCCA TGGGCAAGTA TGTGGACCAG CGGCTGGAGC AGCTTGGCGC CCAGCGAATC 
TTTGAGTTGG GCCTTGGTGA TGACGACGGG AACTTGGAAG AGGATTTCAT CACATGGAGG 
GAGCAGTTCT GGCCAGCTGT GTGCGAGTTC TTCGGGGTGG AAGCCACTGG GGAGGAGTCG 
AGCATCCGCC AGTACGAGCT CGTGGTCCAC GAAGACATGG ACACAGCCAA GGTGTACACG 
GGTGAGATGG GCCGTCTGAA GAGCTACGAG AACCAGAAAC CCCCCTTCGA TGCCAAGAAT 
CCATTCCTGG CTGCTGTCAC CACGAACCGG AAGCTGAACC AAGGCACTGA GAGGCATCTA 
ATGCACCTGG AATTGGACAT CTCAGACTCC AAGATCAGGT ATGAATCTGG AGATCACGTG 
GCTGTGTACC CAGCCAACGA CTCCACCCTG GTCAACCAGA TTGGGGAGAT CCTGGGGGCT 
GACCTGGATG TCATCATGTC TCTAAACAAT CTCGATGAGG AGTCGAATAA GAAGCATCCG 
TTCCCCTGCC CCACCACCTA CCGCACGGCC CTCACCTACT ACCTGGACAT CACTAACCCG 
CCACGAACCA ACGTGCTCTA CGAGCTGGCC CAGTACGCCT CAGAGCCCTC GGAGCAGGAA 
CACCTGCACA AGATGGCGTC CTCCTCCGGC GAGGGCAAGG AGCTGTACCT GAGCTGGGTG 
GTGGAGGCCC GGAGGCACAT CCTAGCCATT CTCCAAGACT ACCCGTCCCT GCGGCCACCC 
ATCGACCACC TGTGCGAGCT CCTCCCGAGG CTGCAGGCCC GCTACTATTC CATTGCCTCG 
TCGTCTAAGG TCCACCCCAA CTCCGTGCAC ATCTGCGCCG TGGCTGTGGA GTATGAAGCG 
AAGTCTGGAC GAGTGAACAA GGGGGTGGCC ACCAGCTGGC TTCGGACCAA GGAACCAGCA 
GGAGAGAATG GCCGCCGGGC CCTGGTCCCC ATGTTCGTCC GCAAGTCCCA GTTCCGCTTG 
CCTTTCAAGC CCACCACACC TGTTATCATG GTGGGCCCCG GCACTGGGGT TGCCCCTTTC 
ATGGGCTTCA TCCAGGAGCG GGCTTGGCTT CGAGAGCAAG GCAAGGAGGT CGGAGAGACG 
CTGCTCTACT ACGGCTGCCG GCGCTCGGAT GAGGACTATC TGTACCGCGA GGAGCTGGCG 
CGCTTCCACA AGGACGGCGC CCTCACGCAG CTTAATGTGG CCTTTTCCCG TGAGCAGGCC 
CACAAGGTCT ATGTTCAGCA CCTGCTCAAG AGGGACAAAG AGCACCTGTG GAAGCTGATC 
CACGAAGGTG GTGCCCACAT CTATGTCTGC GGGGATGCTC GAAATATGGC CAAAGATGTG 
CAGAACACAT TCTATGACAT CGTGGCCGAG TTTGGGCCCA TGGAGCACAC CCAGGCTGTG 
GACTATGTTA AGAAGCTCAT GACCAAGGGC CGCTACTCGC TGGATGTATG GAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Application of hepatic cytochrome b
Toxicology and applied pharmacology36664-74(2019 03)
Reed L,Indra R,Mrizova I,Moserova M,Schmeiser HH,Wolf CR,Henderson CJ,Stiborova M,Phillips DH,Arlt VM

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.
Nature communications8(1)39(2017 06)
Barzi M,Pankowicz FP,Zorman B,Liu X,Legras X,Yang D,Borowiak M,Bissig-Choisat B,Sumazin P,Li F,Bissig KD

Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays.
Free radical biology & medicine10257-66(2017 01)
Rezende F,Prior KK,Löwe O,Wittig I,Strecker V,Moll F,Helfinger V,Schnütgen F,Kurrle N,Wempe F,Walter M,Zukunft S,Luck B,Fleming I,Weissmann N,Brandes RP,Schröder K

Oscillating primary transcripts harbor miRNAs with circadian functions.
Scientific reports621598(2016 Feb)
Wang H,Fan Z,Zhao M,Li J,Lu M,Liu W,Ying H,Liu M,Yan J

Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability.
The Biochemical journal465(3)479-88(2015 Feb)
Henderson CJ,McLaughlin LA,Osuna-Cabello M,Taylor M,Gilbert I,McLaren AW,Wolf CR

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Por cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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