Pcsk6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pcsk6
Entrez Gene ID	18553
Full Name	proprotein convertase subtilisin/kexin type 6
Synonyms	C86343,Pace4,SPC4,b2b2830Clo
General protein information	Preferred Names proprotein convertase subtilisin/kexin type 6 Names proprotein convertase subtilisin/kexin type 6 paired basic amino acid cleaving system 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 C\|7 35.36 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_011048.1	NP_035178.1	proprotein convertase subtilisin/kexin type 6 isoform 1 precursor
NM_001291184.1	NP_001278113.1	proprotein convertase subtilisin/kexin type 6 isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	PCSK6	NP_002561.1
Canis lupus familiaris (dog)	PCSK6	XP_005618782.1
Bos taurus (cattle)	PCSK6	XP_002696700.3
Mus musculus (house mouse)	Pcsk6	NP_035178.1
Rattus norvegicus (Norway rat)	Pcsk6	NP_037131.1
Pan troglodytes (chimpanzee)	PCSK6	XP_001146976.3
Gallus gallus (chicken)	PCSK6	XP_413892.4
Macaca mulatta (Rhesus monkey)	LOC100429418	XP_002805017.1
Xenopus tropicalis (tropical clawed frog)	pcsk6	XP_002939308.2

Gene Ontology
Bibliography

Related articles in PubMed

A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.
Dubos A, Meziane H, Iacono G, Curie A, Riet F, Martin C, Loaëc N, Birling MC, Selloum M, Normand E, Pavlovic G, Sorg T, Stunnenberg HG, Chelly J, Humeau Y, Friocourt G, Hérault Y
Human molecular genetics27(12)2138-2153(2018 06)

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.
Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K
Scientific reports7(1)9322(2017 08)

Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta.
Tunster SJ, McNamara GI, Creeth HDJ, John RM
Developmental biology418(1)55-65(2016 10)

Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation.
Zhang KK, Xiang M, Zhou L, Liu J, Curry N, Heine Suñer D, Garcia-Pavia P, Zhang X, Wang Q, Xie L
Human molecular genetics25(6)1140-51(2016 Mar)

Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture.
Levy R, Mott RF, Iraqi FA, Gabet Y
BMC genomics161013(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pcsk6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pcsk6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15524	NM_011048.1 Latest version!	Mus musculus proprotein convertase subtilisin/kexin type 6 (Pcsk6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu16829	NM_001291184.1 Latest version!	Mus musculus proprotein convertase subtilisin/kexin type 6 (Pcsk6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pcsk6 ( NM_011048.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035178.1 Mus musculus proprotein convertase subtilisin/kexin type 6 (Pcsk6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15524
Clone ID Related Accession (Same CDS sequence)	NM_011048.1
Accession Version	NM_011048.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2880bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1537459200000
Organism	Mus musculus(house mouse)
Product	proprotein convertase subtilisin/kexin type 6 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC165968.3, AC132595.3 and AC148973.4. On or before Jul 2, 2009 this sequence version replaced XM_919493.2, XM_905687.2, XM_355911.4, XM_886136.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCCGC GCGCGCCGCC AGCGCCCGGG CCCCGGCCGC CGCCCCGGGC CGCCGATGTC 
GCGCGGGGCG CAGGGGCCGC CGGCCGGCAC GGACTCCCGC CGCTCGCGCT GCGCCCCTGG 
CGTTGGCTGC TTCTGCTCGC GCTGCCCGCC GCCTGCTCCG CGCTGCCGCC GCCGCGCCCC 
GTCTACACCA ACCACTGGGC AGTGCAAGTG CTGGGCGGCC CCGGCGCGGC GGACCGCGTG 
GCTGCGGCGC ACGGCTACCT CAACTTGGGC CAGATTGGAA ACCTGGACGA TTACTATCAT 
TTTTACCACA GCAAGACCTT CAAGAGATCG ACCTTGAGCA GCAGGGGCCC CCACACCTTC 
CTCAGAATGG ACCCACAGGT AAAATGGCTG CAACAACAGG AAGTGAAGCG CAGAGTCAAG 
AGACAGGCGC GAAGTGACTC TCTTTATTTC AATGATCCCA TTTGGTCTAA CATGTGGTAC 
ATGCATTGTA CTGATAAGAA CAGTCGCTGT CGGTCAGAGA TGAACGTCCA GGCGGCGTGG 
AAGCGTGGCT ACACAGGAAA GAATGTGGTC GTCACCATCC TCGATGACGG CATAGAAAGG 
AATCACCCAG ACCTGGCCCC CAACTACGAT TCCTATGCAA GCTACGATGT CAATGGAAAT 
GATTATGACC CATCCCCGAG ATATGACGCC AGCAACGAGA ACAAACATGG CACTCGCTGT 
GCGGGTGAAG TCGCTGCCTC GGCCAACAAC TCCTACTGCA TCGTGGGCAT CGCATATAAT 
GCAAAGATAG GAGGCATCCG GATGCTGGAC GGCGATGTGA CCGATGTGGT GGAGGCCAAG 
TCTCTGGGCA TCAGACCCAA CTACATTGAC ATTTACAGCG CCAGTTGGGG ACCCGATGAT 
GACGGAAAGA CAGTAGATGG ACCAGGCCGG CTGGCTAAAC AAGCTTTCGA GTATGGCATT 
AAAAAGGGTC GCCAAGGTCT GGGCTCCATT TTTGTTTGGG CCTCTGGGAA TGGTGGGAGA 
GAAGGGGACC ACTGCTCCTG TGATGGCTAC ACCAACAGCA TCTACACCAT CTCCGTAAGC 
AGCACCACTG AGAACGGCCA CAAACCCTGG TACCTGGAAG AATGCGCTTC CACGTTGGCT 
ACCACCTACA GCAGCGGGGC CTTCTATGAA CGGAAGATCG TCACCACAGA TCTGCGTCAG 
CGCTGCACCG ACGGCCACAC TGGGACATCA GTCTCAGCCC CCATGGTGGC TGGTATCATT 
GCCTTGGCTC TAGAAGCAAA CAACCAGTTG ACCTGGAGGG ATGTGCAGCA CCTGCTGGTG 
AAGACATCAC GGCCAGCTCA TCTGAAGGCG AGCGACTGGA AAGTCAACGG AGCTGGGCAT 
AAAGTTAGCC ATCTCTATGG ATTTGGCTTG GTGGATGCAG AAGCTCTGGT CCTGGAGGCG 
AGGAAGTGGA CGGCAGTGCC CTCCCAGCAC GTATGCGTGG CCACCGCAGA CAAAAGGCCC 
AGGAGCATCC CCATAGTGCA GGTGCTACGG ACCACAGCCC TGACCAACGC CTGTGCGGAC 
CACTCAGACC AGCGTGTGGT GTACCTGGAG CATGTGGTTG TCCGAATCTC TATCTCACAC 
CCACGCCGGG GCGATCTCCA GATCCACCTG ATTTCTCCCT CTGGAACCAA GTCTCAACTT 
TTGGCAAAGA GATTGCTGGA TTTTTCCAAT GAGGGGTTCA CAAACTGGGA ATTCATGACC 
GTCCACTGCT GGGGAGAAAA GGCTGAAGGG GAGTGGACTC TGGAAGTGCA GGATATACCA 
TCGCAGGTCC GAAACCCAGA GAAACAAGGA AAGCTGAAAG AATGGAGCCT CATTTTATAT 
GGCACCGCAG AGCACCCATA TCGCACCTTC AGCTCCCATC AGTCTCGCTC ACGGATGCTG 
GAGCTCTCCG TCCCGGAGCA GGAGCCTCCC AAGGCTGCTG GACAACCACC CCAGGCAGAG 
ACTCCAGAAG ACGAGGAAGA GTACACAGCT CCTTCCATCC AAGGCTCTCC TAATACTTTA 
CAGACCAGTG TGTGCCATCC CGAGTGTGGT GACAAAGGCT GTGATGGTCC CAATGCAGAC 
CAGTGCTTGA ACTGTGTCCA CTTCAGCCTG GGGAACTCCA AGACAAACAG GAAGTGTGTG 
AGCGAGTGCC CCTTGGGCTA CTTTGGGGAT GCAGCTGCAA GACGCTGCCG TCGCTGCCAT 
AAGGGATGTG AGACGTGCAC GGGCAGGAGC CCAGCACAGT GCCTGTCTTG TCGCCGTGGG 
TTCTATCACC ACCAGGAGAC GAACACGTGT GTGACCCTCT GTCCTGCCGG ACTTTATGCT 
GATGAAAGTC AGAGACTCTG CCTCAGGTGC CACCCGAGCT GTCAGAAGTG CGTGGATGAA 
CCTGAGAAGT GCACTGTGTG TAAGGAGGGA TTCAGCCTGG CACGGGGCAG CTGCATTCCG 
GACTGTGAAC CGGGTACCTA CTTCGATTCA GAGCTCGTCA AATGTGGGGA ATGCCATCAC 
ACCTGCCGGA CCTGTGTGGG GCCCAGCAGA GAAGAGTGTA TTCACTGTGC AAAAAGCTTC 
CACTTCCAAG ACTGGAAATG TGTGCCGGCC TGCGGTGAGG GCTTCTACCC GGAGGAGATG 
CCTGGCTTAC CCCACAAAGT GTGTCGAAGA TGTGAGGAGA ACTGCCTGAG CTGCGAGGGC 
TCCAGTAGGA ACTGCAGCAG ATGTAAAGCC GGCTTCACAC AGCTGGGAAC CTCCTGCATC 
ACCAACCACA CGTGCAGCAA TGCCGATGAG ACCTTCTGCG AGATGGTGAA GTCCAATCGG 
CTCTGCGAAC GGAAGCTCTT CATCCAGTTT TGCTGCCGCA CCTGCCTCCT GGCTGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035178.1
CDS	36..2915
Translation	MPPRAPPAPGPRPPPRAADVARGAGAAGRHGLPPLALRPWRWLLLLALPAACSALPPPRPVYTNHWAVQVLGGPGAADRVAAAHGYLNLGQIGNLDDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQARSDSLYFNDPIWSNMWYMHCTDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHVCVATADKRPRSIPIVQVLRTTALTNACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTNWEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHPYRTFSSHQSRSRMLELSVPEQEPPKAAGQPPQAETPEDEEEYTAPSIQGSPNTLQTSVCHPECGDKGCDGPNADQCLNCVHFSLGNSKTNRKCVSECPLGYFGDAAARRCRRCHKGCETCTGRSPAQCLSCRRGFYHHQETNTCVTLCPAGLYADESQRLCLRCHPSCQKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELVKCGECHHTCRTCVGPSREECIHCAKSFHFQDWKCVPACGEGFYPEEMPGLPHKVCRRCEENCLSCEGSSRNCSRCKAGFTQLGTSCITNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTCLLAG

Target ORF information:

RefSeq Version	NM_011048.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 6 (Pcsk6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011048.1

ORF Insert Sequence:

ATGCCTCCGC GCGCGCCGCC AGCGCCCGGG CCCCGGCCGC CGCCCCGGGC CGCCGATGTC 
GCGCGGGGCG CAGGGGCCGC CGGCCGGCAC GGACTCCCGC CGCTCGCGCT GCGCCCCTGG 
CGTTGGCTGC TTCTGCTCGC GCTGCCCGCC GCCTGCTCCG CGCTGCCGCC GCCGCGCCCC 
GTCTACACCA ACCACTGGGC AGTGCAAGTG CTGGGCGGCC CCGGCGCGGC GGACCGCGTG 
GCTGCGGCGC ACGGCTACCT CAACTTGGGC CAGATTGGAA ACCTGGACGA TTACTATCAT 
TTTTACCACA GCAAGACCTT CAAGAGATCG ACCTTGAGCA GCAGGGGCCC CCACACCTTC 
CTCAGAATGG ACCCACAGGT AAAATGGCTG CAACAACAGG AAGTGAAGCG CAGAGTCAAG 
AGACAGGCGC GAAGTGACTC TCTTTATTTC AATGATCCCA TTTGGTCTAA CATGTGGTAC 
ATGCATTGTA CTGATAAGAA CAGTCGCTGT CGGTCAGAGA TGAACGTCCA GGCGGCGTGG 
AAGCGTGGCT ACACAGGAAA GAATGTGGTC GTCACCATCC TCGATGACGG CATAGAAAGG 
AATCACCCAG ACCTGGCCCC CAACTACGAT TCCTATGCAA GCTACGATGT CAATGGAAAT 
GATTATGACC CATCCCCGAG ATATGACGCC AGCAACGAGA ACAAACATGG CACTCGCTGT 
GCGGGTGAAG TCGCTGCCTC GGCCAACAAC TCCTACTGCA TCGTGGGCAT CGCATATAAT 
GCAAAGATAG GAGGCATCCG GATGCTGGAC GGCGATGTGA CCGATGTGGT GGAGGCCAAG 
TCTCTGGGCA TCAGACCCAA CTACATTGAC ATTTACAGCG CCAGTTGGGG ACCCGATGAT 
GACGGAAAGA CAGTAGATGG ACCAGGCCGG CTGGCTAAAC AAGCTTTCGA GTATGGCATT 
AAAAAGGGTC GCCAAGGTCT GGGCTCCATT TTTGTTTGGG CCTCTGGGAA TGGTGGGAGA 
GAAGGGGACC ACTGCTCCTG TGATGGCTAC ACCAACAGCA TCTACACCAT CTCCGTAAGC 
AGCACCACTG AGAACGGCCA CAAACCCTGG TACCTGGAAG AATGCGCTTC CACGTTGGCT 
ACCACCTACA GCAGCGGGGC CTTCTATGAA CGGAAGATCG TCACCACAGA TCTGCGTCAG 
CGCTGCACCG ACGGCCACAC TGGGACATCA GTCTCAGCCC CCATGGTGGC TGGTATCATT 
GCCTTGGCTC TAGAAGCAAA CAACCAGTTG ACCTGGAGGG ATGTGCAGCA CCTGCTGGTG 
AAGACATCAC GGCCAGCTCA TCTGAAGGCG AGCGACTGGA AAGTCAACGG AGCTGGGCAT 
AAAGTTAGCC ATCTCTATGG ATTTGGCTTG GTGGATGCAG AAGCTCTGGT CCTGGAGGCG 
AGGAAGTGGA CGGCAGTGCC CTCCCAGCAC GTATGCGTGG CCACCGCAGA CAAAAGGCCC 
AGGAGCATCC CCATAGTGCA GGTGCTACGG ACCACAGCCC TGACCAACGC CTGTGCGGAC 
CACTCAGACC AGCGTGTGGT GTACCTGGAG CATGTGGTTG TCCGAATCTC TATCTCACAC 
CCACGCCGGG GCGATCTCCA GATCCACCTG ATTTCTCCCT CTGGAACCAA GTCTCAACTT 
TTGGCAAAGA GATTGCTGGA TTTTTCCAAT GAGGGGTTCA CAAACTGGGA ATTCATGACC 
GTCCACTGCT GGGGAGAAAA GGCTGAAGGG GAGTGGACTC TGGAAGTGCA GGATATACCA 
TCGCAGGTCC GAAACCCAGA GAAACAAGGA AAGCTGAAAG AATGGAGCCT CATTTTATAT 
GGCACCGCAG AGCACCCATA TCGCACCTTC AGCTCCCATC AGTCTCGCTC ACGGATGCTG 
GAGCTCTCCG TCCCGGAGCA GGAGCCTCCC AAGGCTGCTG GACAACCACC CCAGGCAGAG 
ACTCCAGAAG ACGAGGAAGA GTACACAGCT CCTTCCATCC AAGGCTCTCC TAATACTTTA 
CAGACCAGTG TGTGCCATCC CGAGTGTGGT GACAAAGGCT GTGATGGTCC CAATGCAGAC 
CAGTGCTTGA ACTGTGTCCA CTTCAGCCTG GGGAACTCCA AGACAAACAG GAAGTGTGTG 
AGCGAGTGCC CCTTGGGCTA CTTTGGGGAT GCAGCTGCAA GACGCTGCCG TCGCTGCCAT 
AAGGGATGTG AGACGTGCAC GGGCAGGAGC CCAGCACAGT GCCTGTCTTG TCGCCGTGGG 
TTCTATCACC ACCAGGAGAC GAACACGTGT GTGACCCTCT GTCCTGCCGG ACTTTATGCT 
GATGAAAGTC AGAGACTCTG CCTCAGGTGC CACCCGAGCT GTCAGAAGTG CGTGGATGAA 
CCTGAGAAGT GCACTGTGTG TAAGGAGGGA TTCAGCCTGG CACGGGGCAG CTGCATTCCG 
GACTGTGAAC CGGGTACCTA CTTCGATTCA GAGCTCGTCA AATGTGGGGA ATGCCATCAC 
ACCTGCCGGA CCTGTGTGGG GCCCAGCAGA GAAGAGTGTA TTCACTGTGC AAAAAGCTTC 
CACTTCCAAG ACTGGAAATG TGTGCCGGCC TGCGGTGAGG GCTTCTACCC GGAGGAGATG 
CCTGGCTTAC CCCACAAAGT GTGTCGAAGA TGTGAGGAGA ACTGCCTGAG CTGCGAGGGC 
TCCAGTAGGA ACTGCAGCAG ATGTAAAGCC GGCTTCACAC AGCTGGGAAC CTCCTGCATC 
ACCAACCACA CGTGCAGCAA TGCCGATGAG ACCTTCTGCG AGATGGTGAA GTCCAATCGG 
CTCTGCGAAC GGAAGCTCTT CATCCAGTTT TGCTGCCGCA CCTGCCTCCT GGCTGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pcsk6 ( NM_001291184.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001278113.1 Mus musculus proprotein convertase subtilisin/kexin type 6 (Pcsk6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu16829
Clone ID Related Accession (Same CDS sequence)	NM_001291184.1
Accession Version	NM_001291184.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2841bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1537632000000
Organism	Mus musculus(house mouse)
Product	proprotein convertase subtilisin/kexin type 6 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC165968.3, AC132595.3 and AC148973.4. On Mar 27, 2014 this sequence version replaced XM_006540706.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D50060.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCCGC GCGCGCCGCC AGCGCCCGGG CCCCGGCCGC CGCCCCGGGC CGCCGATGTC 
GCGCGGGGCG CAGGGGCCGC CGGCCGGCAC GGACTCCCGC CGCTCGCGCT GCGCCCCTGG 
CGTTGGCTGC TTCTGCTCGC GCTGCCCGCC GCCTGCTCCG CGCTGCCGCC GCCGCGCCCC 
GTCTACACCA ACCACTGGGC AGTGCAAGTG CTGGGCGGCC CCGGCGCGGC GGACCGCGTG 
GCTGCGGCGC ACGGCTACCT CAACTTGGGC CAGATTGGAA ACCTGGACGA TTACTATCAT 
TTTTACCACA GCAAGACCTT CAAGAGATCG ACCTTGAGCA GCAGGGGCCC CCACACCTTC 
CTCAGAATGG ACCCACAGGT AAAATGGCTG CAACAACAGG AAGTGAAGCG CAGAGTCAAG 
AGACAGGCGC GAAGTGACTC TCTTTATTTC AATGATCCCA TTTGGTCTAA CATGTGGTAC 
ATGCATTGTA CTGATAAGAA CAGTCGCTGT CGGTCAGAGA TGAACGTCCA GGCGGCGTGG 
AAGCGTGGCT ACACAGGAAA GAATGTGGTC GTCACCATCC TCGATGACGG CATAGAAAGG 
AATCACCCAG ACCTGGCCCC CAACTACGAT TCCTATGCAA GCTACGATGT CAATGGAAAT 
GATTATGACC CATCCCCGAG ATATGACGCC AGCAACGAGA ACAAACATGG CACTCGCTGT 
GCGGGTGAAG TCGCTGCCTC GGCCAACAAC TCCTACTGCA TCGTGGGCAT CGCATATAAT 
GCAAAGATAG GAGGCATCCG GATGCTGGAC GGCGATGTGA CCGATGTGGT GGAGGCCAAG 
TCTCTGGGCA TCAGACCCAA CTACATTGAC ATTTACAGCG CCAGTTGGGG ACCCGATGAT 
GACGGAAAGA CAGTAGATGG ACCAGGCCGG CTGGCTAAAC AAGCTTTCGA GTATGGCATT 
AAAAAGGGTC GCCAAGGTCT GGGCTCCATT TTTGTTTGGG CCTCTGGGAA TGGTGGGAGA 
GAAGGGGACC ACTGCTCCTG TGATGGCTAC ACCAACAGCA TCTACACCAT CTCCGTAAGC 
AGCACCACTG AGAACGGCCA CAAACCCTGG TACCTGGAAG AATGCGCTTC CACGTTGGCT 
ACCACCTACA GCAGCGGGGC CTTCTATGAA CGGAAGATCG TCACCACAGA TCTGCGTCAG 
CGCTGCACCG ACGGCCACAC TGGGACATCA GTCTCAGCCC CCATGGTGGC TGGTATCATT 
GCCTTGGCTC TAGAAGCAAA CAACCAGTTG ACCTGGAGGG ATGTGCAGCA CCTGCTGGTG 
AAGACATCAC GGCCAGCTCA TCTGAAGGCG AGCGACTGGA AAGTCAACGG AGCTGGGCAT 
AAAGTTAGCC ATCTCTATGG ATTTGGCTTG GTGGATGCAG AAGCTCTGGT CCTGGAGGCG 
AGGAAGTGGA CGGCAGTGCC CTCCCAGCAC GTATGCGTGG CCACCGCAGA CAAAAGGCCC 
AGGAGCATCC CCATAGTGCA GGTGCTACGG ACCACAGCCC TGACCAACGC CTGTGCGGAC 
CACTCAGACC AGCGTGTGGT GTACCTGGAG CATGTGGTTG TCCGAATCTC TATCTCACAC 
CCACGCCGGG GCGATCTCCA GATCCACCTG ATTTCTCCCT CTGGAACCAA GTCTCAACTT 
TTGGCAAAGA GATTGCTGGA TTTTTCCAAT GAGGGGTTCA CAAACTGGGA ATTCATGACC 
GTCCACTGCT GGGGAGAAAA GGCTGAAGGG GAGTGGACTC TGGAAGTGCA GGATATACCA 
TCGCAGGTCC GAAACCCAGA GAAACAAGGA AAGCTGAAAG AATGGAGCCT CATTTTATAT 
GGCACCGCAG AGCACCCATA TCGCACCTTC AGCTCCCATC AGTCTCGCTC ACGGATGCTG 
GAGCTCTCCG TCCCGGAGCA GGAGCCTCCC AAGGCTGCTG GACAACCACC CCAGGCAGAG 
ACTCCAGAAG ACGAGGAAGA GTACACAGGT GTGTGCCATC CCGAGTGTGG TGACAAAGGC 
TGTGATGGTC CCAATGCAGA CCAGTGCTTG AACTGTGTCC ACTTCAGCCT GGGGAACTCC 
AAGACAAACA GGAAGTGTGT GAGCGAGTGC CCCTTGGGCT ACTTTGGGGA TGCAGCTGCA 
AGACGCTGCC GTCGCTGCCA TAAGGGATGT GAGACGTGCA CGGGCAGGAG CCCAGCACAG 
TGCCTGTCTT GTCGCCGTGG GTTCTATCAC CACCAGGAGA CGAACACGTG TGTGACCCTC 
TGTCCTGCCG GACTTTATGC TGATGAAAGT CAGAGACTCT GCCTCAGGTG CCACCCGAGC 
TGTCAGAAGT GCGTGGATGA ACCTGAGAAG TGCACTGTGT GTAAGGAGGG ATTCAGCCTG 
GCACGGGGCA GCTGCATTCC GGACTGTGAA CCGGGTACCT ACTTCGATTC AGAGCTCGTC 
AAATGTGGGG AATGCCATCA CACCTGCCGG ACCTGTGTGG GGCCCAGCAG AGAAGAGTGT 
ATTCACTGTG CAAAAAGCTT CCACTTCCAA GACTGGAAAT GTGTGCCGGC CTGCGGTGAG 
GGCTTCTACC CGGAGGAGAT GCCTGGCTTA CCCCACAAAG TGTGTCGAAG ATGTGAGGAG 
AACTGCCTGA GCTGCGAGGG CTCCAGTAGG AACTGCAGCA GATGTAAAGC CGGCTTCACA 
CAGCTGGGAA CCTCCTGCAT CACCAACCAC ACGTGCAGCA ATGCCGATGA GACCTTCTGC 
GAGATGGTGA AGTCCAATCG GCTCTGCGAA CGGAAGCTCT TCATCCAGTT TTGCTGCCGC 
ACCTGCCTCC TGGCTGGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278113.1
CDS	36..2876
Translation	MPPRAPPAPGPRPPPRAADVARGAGAAGRHGLPPLALRPWRWLLLLALPAACSALPPPRPVYTNHWAVQVLGGPGAADRVAAAHGYLNLGQIGNLDDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQARSDSLYFNDPIWSNMWYMHCTDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHVCVATADKRPRSIPIVQVLRTTALTNACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTNWEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHPYRTFSSHQSRSRMLELSVPEQEPPKAAGQPPQAETPEDEEEYTGVCHPECGDKGCDGPNADQCLNCVHFSLGNSKTNRKCVSECPLGYFGDAAARRCRRCHKGCETCTGRSPAQCLSCRRGFYHHQETNTCVTLCPAGLYADESQRLCLRCHPSCQKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELVKCGECHHTCRTCVGPSREECIHCAKSFHFQDWKCVPACGEGFYPEEMPGLPHKVCRRCEENCLSCEGSSRNCSRCKAGFTQLGTSCITNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTCLLAG

Target ORF information:

RefSeq Version	NM_001291184.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus proprotein convertase subtilisin/kexin type 6 (Pcsk6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291184.1

ORF Insert Sequence:

ATGCCTCCGC GCGCGCCGCC AGCGCCCGGG CCCCGGCCGC CGCCCCGGGC CGCCGATGTC 
GCGCGGGGCG CAGGGGCCGC CGGCCGGCAC GGACTCCCGC CGCTCGCGCT GCGCCCCTGG 
CGTTGGCTGC TTCTGCTCGC GCTGCCCGCC GCCTGCTCCG CGCTGCCGCC GCCGCGCCCC 
GTCTACACCA ACCACTGGGC AGTGCAAGTG CTGGGCGGCC CCGGCGCGGC GGACCGCGTG 
GCTGCGGCGC ACGGCTACCT CAACTTGGGC CAGATTGGAA ACCTGGACGA TTACTATCAT 
TTTTACCACA GCAAGACCTT CAAGAGATCG ACCTTGAGCA GCAGGGGCCC CCACACCTTC 
CTCAGAATGG ACCCACAGGT AAAATGGCTG CAACAACAGG AAGTGAAGCG CAGAGTCAAG 
AGACAGGCGC GAAGTGACTC TCTTTATTTC AATGATCCCA TTTGGTCTAA CATGTGGTAC 
ATGCATTGTA CTGATAAGAA CAGTCGCTGT CGGTCAGAGA TGAACGTCCA GGCGGCGTGG 
AAGCGTGGCT ACACAGGAAA GAATGTGGTC GTCACCATCC TCGATGACGG CATAGAAAGG 
AATCACCCAG ACCTGGCCCC CAACTACGAT TCCTATGCAA GCTACGATGT CAATGGAAAT 
GATTATGACC CATCCCCGAG ATATGACGCC AGCAACGAGA ACAAACATGG CACTCGCTGT 
GCGGGTGAAG TCGCTGCCTC GGCCAACAAC TCCTACTGCA TCGTGGGCAT CGCATATAAT 
GCAAAGATAG GAGGCATCCG GATGCTGGAC GGCGATGTGA CCGATGTGGT GGAGGCCAAG 
TCTCTGGGCA TCAGACCCAA CTACATTGAC ATTTACAGCG CCAGTTGGGG ACCCGATGAT 
GACGGAAAGA CAGTAGATGG ACCAGGCCGG CTGGCTAAAC AAGCTTTCGA GTATGGCATT 
AAAAAGGGTC GCCAAGGTCT GGGCTCCATT TTTGTTTGGG CCTCTGGGAA TGGTGGGAGA 
GAAGGGGACC ACTGCTCCTG TGATGGCTAC ACCAACAGCA TCTACACCAT CTCCGTAAGC 
AGCACCACTG AGAACGGCCA CAAACCCTGG TACCTGGAAG AATGCGCTTC CACGTTGGCT 
ACCACCTACA GCAGCGGGGC CTTCTATGAA CGGAAGATCG TCACCACAGA TCTGCGTCAG 
CGCTGCACCG ACGGCCACAC TGGGACATCA GTCTCAGCCC CCATGGTGGC TGGTATCATT 
GCCTTGGCTC TAGAAGCAAA CAACCAGTTG ACCTGGAGGG ATGTGCAGCA CCTGCTGGTG 
AAGACATCAC GGCCAGCTCA TCTGAAGGCG AGCGACTGGA AAGTCAACGG AGCTGGGCAT 
AAAGTTAGCC ATCTCTATGG ATTTGGCTTG GTGGATGCAG AAGCTCTGGT CCTGGAGGCG 
AGGAAGTGGA CGGCAGTGCC CTCCCAGCAC GTATGCGTGG CCACCGCAGA CAAAAGGCCC 
AGGAGCATCC CCATAGTGCA GGTGCTACGG ACCACAGCCC TGACCAACGC CTGTGCGGAC 
CACTCAGACC AGCGTGTGGT GTACCTGGAG CATGTGGTTG TCCGAATCTC TATCTCACAC 
CCACGCCGGG GCGATCTCCA GATCCACCTG ATTTCTCCCT CTGGAACCAA GTCTCAACTT 
TTGGCAAAGA GATTGCTGGA TTTTTCCAAT GAGGGGTTCA CAAACTGGGA ATTCATGACC 
GTCCACTGCT GGGGAGAAAA GGCTGAAGGG GAGTGGACTC TGGAAGTGCA GGATATACCA 
TCGCAGGTCC GAAACCCAGA GAAACAAGGA AAGCTGAAAG AATGGAGCCT CATTTTATAT 
GGCACCGCAG AGCACCCATA TCGCACCTTC AGCTCCCATC AGTCTCGCTC ACGGATGCTG 
GAGCTCTCCG TCCCGGAGCA GGAGCCTCCC AAGGCTGCTG GACAACCACC CCAGGCAGAG 
ACTCCAGAAG ACGAGGAAGA GTACACAGGT GTGTGCCATC CCGAGTGTGG TGACAAAGGC 
TGTGATGGTC CCAATGCAGA CCAGTGCTTG AACTGTGTCC ACTTCAGCCT GGGGAACTCC 
AAGACAAACA GGAAGTGTGT GAGCGAGTGC CCCTTGGGCT ACTTTGGGGA TGCAGCTGCA 
AGACGCTGCC GTCGCTGCCA TAAGGGATGT GAGACGTGCA CGGGCAGGAG CCCAGCACAG 
TGCCTGTCTT GTCGCCGTGG GTTCTATCAC CACCAGGAGA CGAACACGTG TGTGACCCTC 
TGTCCTGCCG GACTTTATGC TGATGAAAGT CAGAGACTCT GCCTCAGGTG CCACCCGAGC 
TGTCAGAAGT GCGTGGATGA ACCTGAGAAG TGCACTGTGT GTAAGGAGGG ATTCAGCCTG 
GCACGGGGCA GCTGCATTCC GGACTGTGAA CCGGGTACCT ACTTCGATTC AGAGCTCGTC 
AAATGTGGGG AATGCCATCA CACCTGCCGG ACCTGTGTGG GGCCCAGCAG AGAAGAGTGT 
ATTCACTGTG CAAAAAGCTT CCACTTCCAA GACTGGAAAT GTGTGCCGGC CTGCGGTGAG 
GGCTTCTACC CGGAGGAGAT GCCTGGCTTA CCCCACAAAG TGTGTCGAAG ATGTGAGGAG 
AACTGCCTGA GCTGCGAGGG CTCCAGTAGG AACTGCAGCA GATGTAAAGC CGGCTTCACA 
CAGCTGGGAA CCTCCTGCAT CACCAACCAC ACGTGCAGCA ATGCCGATGA GACCTTCTGC 
GAGATGGTGA AGTCCAATCG GCTCTGCGAA CGGAAGCTCT TCATCCAGTT TTGCTGCCGC 
ACCTGCCTCC TGGCTGGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.
Human molecular genetics27(12)2138-2153(2018 06)
Dubos A,Meziane H,Iacono G,Curie A,Riet F,Martin C,Loaëc N,Birling MC,Selloum M,Normand E,Pavlovic G,Sorg T,Stunnenberg HG,Chelly J,Humeau Y,Friocourt G,Hérault Y

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.
Scientific reports7(1)9322(2017 08)
Bhargava S,Cox B,Polydorou C,Gresakova V,Korinek V,Strnad H,Sedlacek R,Epp TA,Chawengsaksophak K

Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta.
Developmental biology418(1)55-65(2016 10)
Tunster SJ,McNamara GI,Creeth HDJ,John RM

Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation.
Human molecular genetics25(6)1140-51(2016 Mar)
Zhang KK,Xiang M,Zhou L,Liu J,Curry N,Heine Suñer D,Garcia-Pavia P,Zhang X,Wang Q,Xie L

Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture.
BMC genomics161013(2015 Nov)
Levy R,Mott RF,Iraqi FA,Gabet Y

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Pcsk6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM