P4hb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	P4hb
Entrez Gene ID	18453
Full Name	prolyl 4-hydroxylase, beta polypeptide
Synonyms	ERp59,PDI,Pdia1,Thbp
General protein information	Preferred Names prolyl 4-hydroxylase, beta polypeptide Names protein disulfide-isomerase ER protein 59 cellular thyroid hormone-binding protein endoplasmic reticulum resident protein 59 p55 prolyl 4-hydroxylase subunit beta
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 E2\|11 84.27 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_011032.2	NP_035162.1	protein disulfide-isomerase precursor
NM_011032.3	NP_035162.1	protein disulfide-isomerase precursor

Pathways from BioSystems

Homologies

Eremothecium gossypii	AGOS_AFR718W	NP_986266.2
Canis lupus familiaris (dog)	P4HB	XP_540488.2
Mus musculus (house mouse)	P4hb	NP_035162.1
Rattus norvegicus (Norway rat)	P4hb	NP_037130.1
Gallus gallus (chicken)	P4HB	NP_001185639.1
Danio rerio (zebrafish)	p4hb	NP_998529.3
Arabidopsis thaliana (thale cress)	PDIL1-4	NP_851234.1
Xenopus tropicalis (tropical clawed frog)	p4hb	NP_001034820.1
Oryza sativa (rice)	Os02g0100100	NP_001045579.1
Neurospora crassa	NCU09223	XP_959167.1
Homo sapiens (human)	P4HB	NP_000909.2
Pan troglodytes (chimpanzee)	P4HB	NP_001233358.1
Drosophila melanogaster (fruit fly)	Pdi	NP_524079.1
Saccharomyces cerevisiae (baker's yeast)	PDI1	NP_009887.1
Caenorhabditis elegans (roundworm)	pdi-2	NP_508778.1
Arabidopsis thaliana (thale cress)	PDIL1-3	NP_191056.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012407	XP_551775.3
Macaca mulatta (Rhesus monkey)	LOC714702	XP_002800695.1
Kluyveromyces lactis	KLLA0C01111g	XP_452244.1
Magnaporthe oryzae (rice blast fungus)	MGG_05753	XP_003710672.1
Schizosaccharomyces pombe (fission yeast)	SPAC1F5.02	NP_592871.1
Bos taurus (cattle)	P4HB	NP_776560.1

Gene Ontology
Bibliography

Related articles in PubMed

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
Jang I, Pottekat A, Poothong J, Yong J, Lagunas-Acosta J, Charbono A, Chen Z, Scheuner DL, Liu M, Itkin-Ansari P, Arvan P, Kaufman RJ
eLife8(2019 06)

CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y
Development (Cambridge, England)146(2)(2019 01)

Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans.
Funato N, Yanagisawa H
Archives of oral biology95149-155(2018 Nov)

Protein disulfide isomerase as a prosurvival factor in cell therapy for muscular and vascular diseases.
Di Rocco G, Baldari S, Gentile A, Capogrossi M, Toietta G
Stem cell research & therapy9(1)250(2018 09)

Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence.
Kim YM, Youn SW, Sudhahar V, Das A, Chandhri R, Cuervo Grajal H, Kweon J, Leanhart S, He L, Toth PT, Kitajewski J, Rehman J, Yoon Y, Cho J, Fukai T, Ushio-Fukai M
Cell reports23(12)3565-3578(2018 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following P4hb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the P4hb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu22643	NM_011032.3 Latest version!	Mus musculus prolyl 4-hydroxylase, beta polypeptide (P4hb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu22643	NM_011032.2	Mus musculus prolyl 4-hydroxylase, beta polypeptide (P4hb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

P4hb ( NM_011032.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035162.1 Mus musculus prolyl 4-hydroxylase, beta polypeptide (P4hb), mRNA.

Price & Availability↑

CloneID	OMu22643
Clone ID Related Accession (Same CDS sequence)	NM_011032.2 , NM_011032.3
Accession Version	NM_011032.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514304000000
Organism	Mus musculus(house mouse)
Product	protein disulfide-isomerase precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL663030.12. On Nov 17, 2006 this sequence version replaced NM_011032.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J05185.1, AK150002.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGCTGAGCC GTGCTTTGCT GTGCCTAGCC CTGGCCTGGG CGGCTAGGGT GGGCGCCGAC 
GCCCTGGAGG AGGAGGACAA CGTCCTGGTG TTGAAGAAGA GCAACTTCGA GGAGGCGCTG 
GCGGCGCACA AGTACCTGCT GGTGGAGTTC TATGCCCCGT GGTGTGGCCA CTGCAAAGCT 
CTGGCTCCCG AGTATGCCAA AGCTGCCGCA AAACTGAAGG CAGAAGGCTC TGAGATTCGA 
CTAGCAAAGG TGGATGCCAC AGAAGAGTCT GACCTGGCTC AGCAGTATGG TGTCCGTGGC 
TACCCCACAA TCAAGTTCTT CAAGAATGGA GACACAGCCT CCCCAAAGGA ATATACAGCT 
GGCAGGGAAG CTGATGACAT TGTCAACTGG CTGAAGAAAC GCACGGGCCC AGCAGCTACA 
ACCCTGTCTG ACACTGCAGC TGCAGAGTCC TTGGTGGACT CAAGCGAAGT GACGGTCATC 
GGTTTCTTCA AGGACGTAGA GTCAGACTCT GCCAAGCAGT TCTTGCTGGC AGCAGAGGCT 
ATTGATGACA TACCTTTTGG AATCACGTCC AACAGTGGTG TGTTCTCCAA GTACCAGCTG 
GACAAAGATG GGGTGGTCCT CTTTAAGAAG TTTGATGAAG GCCGCAACAA CTTTGAGGGT 
GAGATCACCA AGGAGAAGCT TCTAGACTTC ATCAAGCACA ATCAGCTGCC TTTGGTCATC 
GAGTTCACTG AACAGACAGC TCCGAAGATT TTTGGAGGTG AGATCAAGAC ACACATTCTG 
CTGTTCCTGC CCAAGAGTGT ATCTGACTAT GACGGCAAGC TGAGCAGCTT CAAGAGAGCA 
GCCGAGGGCT TCAAGGGCAA GATCCTATTT ATCTTCATCG ATAGCGACCA CACTGATAAC 
CAGCGCATAC TTGAGTTCTT TGGCCTGAAG AAGGAGGAGT GTCCCGCTGT GCGGCTTATT 
ACCCTAGAGG AAGAGATGAC CAAGTACAAA CCAGAGTCAG ATGAGCTGAC GGCTGAGAAA 
ATCACAGAGT TTTGCCACCG CTTCTTAGAG GGCAAGATCA AGCCCCACCT GATGAGCCAA 
GAAGTGCCTG AAGACTGGGA CAAACAGCCG GTAAAAGTAC TGGTTGGGGC GAACTTTGAA 
GAGGTCGCTT TTGATGAGAA AAAGAACGTG TTTGTTGAAT TCTATGCCCC TTGGTGTGGT 
CACTGCAAGC AGCTAGCCCC CATTTGGGAT AAACTGGGAG AGACATACAA GGATCATGAG 
AATATCATCA TTGCTAAGAT GGACTCAACA GCCAATGAGG TGGAAGCTGT CAAAGTACAT 
AGCTTTCCCA CACTGAAGTT CTTCCCAGCA AGTGCAGACA GAACGGTCAT TGATTACAAC 
GGCGAGCGGA CACTGGACGG TTTTAAGAAA TTCTTGGAGA GTGGTGGCCA GGATGGAGCA 
GGGGACGATG AGGACCTCGA CCTAGAAGAA GCTTTAGAGC CAGACATGGA GGAAGACGAC 
GATCAGAAAG CTGTGAAGGA TGAACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035162.1
CDS	130..1659
Translation	MLSRALLCLALAWAARVGADALEEEDNVLVLKKSNFEEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTAAAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEAIDDIPFGITSNSGVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSSFKRAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDEDLDLEEALEPDMEEDDDQKAVKDEL

Target ORF information:

RefSeq Version	NM_011032.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolyl 4-hydroxylase, beta polypeptide (P4hb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011032.2

ORF Insert Sequence:

ATGCTGAGCC GTGCTTTGCT GTGCCTAGCC CTGGCCTGGG CGGCTAGGGT GGGCGCCGAC 
GCCCTGGAGG AGGAGGACAA CGTCCTGGTG TTGAAGAAGA GCAACTTCGA GGAGGCGCTG 
GCGGCGCACA AGTACCTGCT GGTGGAGTTC TATGCCCCGT GGTGTGGCCA CTGCAAAGCT 
CTGGCTCCCG AGTATGCCAA AGCTGCCGCA AAACTGAAGG CAGAAGGCTC TGAGATTCGA 
CTAGCAAAGG TGGATGCCAC AGAAGAGTCT GACCTGGCTC AGCAGTATGG TGTCCGTGGC 
TACCCCACAA TCAAGTTCTT CAAGAATGGA GACACAGCCT CCCCAAAGGA ATATACAGCT 
GGCAGGGAAG CTGATGACAT TGTCAACTGG CTGAAGAAAC GCACGGGCCC AGCAGCTACA 
ACCCTGTCTG ACACTGCAGC TGCAGAGTCC TTGGTGGACT CAAGCGAAGT GACGGTCATC 
GGTTTCTTCA AGGACGTAGA GTCAGACTCT GCCAAGCAGT TCTTGCTGGC AGCAGAGGCT 
ATTGATGACA TACCTTTTGG AATCACGTCC AACAGTGGTG TGTTCTCCAA GTACCAGCTG 
GACAAAGATG GGGTGGTCCT CTTTAAGAAG TTTGATGAAG GCCGCAACAA CTTTGAGGGT 
GAGATCACCA AGGAGAAGCT TCTAGACTTC ATCAAGCACA ATCAGCTGCC TTTGGTCATC 
GAGTTCACTG AACAGACAGC TCCGAAGATT TTTGGAGGTG AGATCAAGAC ACACATTCTG 
CTGTTCCTGC CCAAGAGTGT ATCTGACTAT GACGGCAAGC TGAGCAGCTT CAAGAGAGCA 
GCCGAGGGCT TCAAGGGCAA GATCCTATTT ATCTTCATCG ATAGCGACCA CACTGATAAC 
CAGCGCATAC TTGAGTTCTT TGGCCTGAAG AAGGAGGAGT GTCCCGCTGT GCGGCTTATT 
ACCCTAGAGG AAGAGATGAC CAAGTACAAA CCAGAGTCAG ATGAGCTGAC GGCTGAGAAA 
ATCACAGAGT TTTGCCACCG CTTCTTAGAG GGCAAGATCA AGCCCCACCT GATGAGCCAA 
GAAGTGCCTG AAGACTGGGA CAAACAGCCG GTAAAAGTAC TGGTTGGGGC GAACTTTGAA 
GAGGTCGCTT TTGATGAGAA AAAGAACGTG TTTGTTGAAT TCTATGCCCC TTGGTGTGGT 
CACTGCAAGC AGCTAGCCCC CATTTGGGAT AAACTGGGAG AGACATACAA GGATCATGAG 
AATATCATCA TTGCTAAGAT GGACTCAACA GCCAATGAGG TGGAAGCTGT CAAAGTACAT 
AGCTTTCCCA CACTGAAGTT CTTCCCAGCA AGTGCAGACA GAACGGTCAT TGATTACAAC 
GGCGAGCGGA CACTGGACGG TTTTAAGAAA TTCTTGGAGA GTGGTGGCCA GGATGGAGCA 
GGGGACGATG AGGACCTCGA CCTAGAAGAA GCTTTAGAGC CAGACATGGA GGAAGACGAC 
GATCAGAAAG CTGTGAAGGA TGAACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P4hb ( NM_011032.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035162.1 Mus musculus prolyl 4-hydroxylase, beta polypeptide (P4hb), mRNA.

Price & Availability↑

CloneID	OMu22643
Clone ID Related Accession (Same CDS sequence)	NM_011032.2 , NM_011032.3
Accession Version	NM_011032.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Mus musculus(house mouse)
Product	protein disulfide-isomerase precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA317831.1, AK159606.1 and BP766087.1. On Feb 22, 2018 this sequence version replaced NM_011032.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J05185.1, AK150002.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGAGCC GTGCTTTGCT GTGCCTAGCC CTGGCCTGGG CGGCTAGGGT GGGCGCCGAC 
GCCCTGGAGG AGGAGGACAA CGTCCTGGTG TTGAAGAAGA GCAACTTCGA GGAGGCGCTG 
GCGGCGCACA AGTACCTGCT GGTGGAGTTC TATGCCCCGT GGTGTGGCCA CTGCAAAGCT 
CTGGCTCCCG AGTATGCCAA AGCTGCCGCA AAACTGAAGG CAGAAGGCTC TGAGATTCGA 
CTAGCAAAGG TGGATGCCAC AGAAGAGTCT GACCTGGCTC AGCAGTATGG TGTCCGTGGC 
TACCCCACAA TCAAGTTCTT CAAGAATGGA GACACAGCCT CCCCAAAGGA ATATACAGCT 
GGCAGGGAAG CTGATGACAT TGTCAACTGG CTGAAGAAAC GCACGGGCCC AGCAGCTACA 
ACCCTGTCTG ACACTGCAGC TGCAGAGTCC TTGGTGGACT CAAGCGAAGT GACGGTCATC 
GGTTTCTTCA AGGACGTAGA GTCAGACTCT GCCAAGCAGT TCTTGCTGGC AGCAGAGGCT 
ATTGATGACA TACCTTTTGG AATCACGTCC AACAGTGGTG TGTTCTCCAA GTACCAGCTG 
GACAAAGATG GGGTGGTCCT CTTTAAGAAG TTTGATGAAG GCCGCAACAA CTTTGAGGGT 
GAGATCACCA AGGAGAAGCT TCTAGACTTC ATCAAGCACA ATCAGCTGCC TTTGGTCATC 
GAGTTCACTG AACAGACAGC TCCGAAGATT TTTGGAGGTG AGATCAAGAC ACACATTCTG 
CTGTTCCTGC CCAAGAGTGT ATCTGACTAT GACGGCAAGC TGAGCAGCTT CAAGAGAGCA 
GCCGAGGGCT TCAAGGGCAA GATCCTATTT ATCTTCATCG ATAGCGACCA CACTGATAAC 
CAGCGCATAC TTGAGTTCTT TGGCCTGAAG AAGGAGGAGT GTCCCGCTGT GCGGCTTATT 
ACCCTAGAGG AAGAGATGAC CAAGTACAAA CCAGAGTCAG ATGAGCTGAC GGCTGAGAAA 
ATCACAGAGT TTTGCCACCG CTTCTTAGAG GGCAAGATCA AGCCCCACCT GATGAGCCAA 
GAAGTGCCTG AAGACTGGGA CAAACAGCCG GTAAAAGTAC TGGTTGGGGC GAACTTTGAA 
GAGGTCGCTT TTGATGAGAA AAAGAACGTG TTTGTTGAAT TCTATGCCCC TTGGTGTGGT 
CACTGCAAGC AGCTAGCCCC CATTTGGGAT AAACTGGGAG AGACATACAA GGATCATGAG 
AATATCATCA TTGCTAAGAT GGACTCAACA GCCAATGAGG TGGAAGCTGT CAAAGTACAT 
AGCTTTCCCA CACTGAAGTT CTTCCCAGCA AGTGCAGACA GAACGGTCAT TGATTACAAC 
GGCGAGCGGA CACTGGACGG TTTTAAGAAA TTCTTGGAGA GTGGTGGCCA GGATGGAGCA 
GGGGACGATG AGGACCTCGA CCTAGAAGAA GCTTTAGAGC CAGACATGGA GGAAGACGAC 
GATCAGAAAG CTGTGAAGGA TGAACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035162.1
CDS	447..1976
Translation	MLSRALLCLALAWAARVGADALEEEDNVLVLKKSNFEEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTAAAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEAIDDIPFGITSNSGVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSSFKRAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDEDLDLEEALEPDMEEDDDQKAVKDEL

Target ORF information:

RefSeq Version	NM_011032.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolyl 4-hydroxylase, beta polypeptide (P4hb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011032.3

ORF Insert Sequence:

ATGCTGAGCC GTGCTTTGCT GTGCCTAGCC CTGGCCTGGG CGGCTAGGGT GGGCGCCGAC 
GCCCTGGAGG AGGAGGACAA CGTCCTGGTG TTGAAGAAGA GCAACTTCGA GGAGGCGCTG 
GCGGCGCACA AGTACCTGCT GGTGGAGTTC TATGCCCCGT GGTGTGGCCA CTGCAAAGCT 
CTGGCTCCCG AGTATGCCAA AGCTGCCGCA AAACTGAAGG CAGAAGGCTC TGAGATTCGA 
CTAGCAAAGG TGGATGCCAC AGAAGAGTCT GACCTGGCTC AGCAGTATGG TGTCCGTGGC 
TACCCCACAA TCAAGTTCTT CAAGAATGGA GACACAGCCT CCCCAAAGGA ATATACAGCT 
GGCAGGGAAG CTGATGACAT TGTCAACTGG CTGAAGAAAC GCACGGGCCC AGCAGCTACA 
ACCCTGTCTG ACACTGCAGC TGCAGAGTCC TTGGTGGACT CAAGCGAAGT GACGGTCATC 
GGTTTCTTCA AGGACGTAGA GTCAGACTCT GCCAAGCAGT TCTTGCTGGC AGCAGAGGCT 
ATTGATGACA TACCTTTTGG AATCACGTCC AACAGTGGTG TGTTCTCCAA GTACCAGCTG 
GACAAAGATG GGGTGGTCCT CTTTAAGAAG TTTGATGAAG GCCGCAACAA CTTTGAGGGT 
GAGATCACCA AGGAGAAGCT TCTAGACTTC ATCAAGCACA ATCAGCTGCC TTTGGTCATC 
GAGTTCACTG AACAGACAGC TCCGAAGATT TTTGGAGGTG AGATCAAGAC ACACATTCTG 
CTGTTCCTGC CCAAGAGTGT ATCTGACTAT GACGGCAAGC TGAGCAGCTT CAAGAGAGCA 
GCCGAGGGCT TCAAGGGCAA GATCCTATTT ATCTTCATCG ATAGCGACCA CACTGATAAC 
CAGCGCATAC TTGAGTTCTT TGGCCTGAAG AAGGAGGAGT GTCCCGCTGT GCGGCTTATT 
ACCCTAGAGG AAGAGATGAC CAAGTACAAA CCAGAGTCAG ATGAGCTGAC GGCTGAGAAA 
ATCACAGAGT TTTGCCACCG CTTCTTAGAG GGCAAGATCA AGCCCCACCT GATGAGCCAA 
GAAGTGCCTG AAGACTGGGA CAAACAGCCG GTAAAAGTAC TGGTTGGGGC GAACTTTGAA 
GAGGTCGCTT TTGATGAGAA AAAGAACGTG TTTGTTGAAT TCTATGCCCC TTGGTGTGGT 
CACTGCAAGC AGCTAGCCCC CATTTGGGAT AAACTGGGAG AGACATACAA GGATCATGAG 
AATATCATCA TTGCTAAGAT GGACTCAACA GCCAATGAGG TGGAAGCTGT CAAAGTACAT 
AGCTTTCCCA CACTGAAGTT CTTCCCAGCA AGTGCAGACA GAACGGTCAT TGATTACAAC 
GGCGAGCGGA CACTGGACGG TTTTAAGAAA TTCTTGGAGA GTGGTGGCCA GGATGGAGCA 
GGGGACGATG AGGACCTCGA CCTAGAAGAA GCTTTAGAGC CAGACATGGA GGAAGACGAC 
GATCAGAAAG CTGTGAAGGA TGAACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
eLife8(2019 06)
Jang I,Pottekat A,Poothong J,Yong J,Lagunas-Acosta J,Charbono A,Chen Z,Scheuner DL,Liu M,Itkin-Ansari P,Arvan P,Kaufman RJ

CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Development (Cambridge, England)146(2)(2019 01)
Yang R,Wang H,Kang B,Chen B,Shi Y,Yang S,Sun L,Liu Y,Xiao W,Zhang T,Yang J,Zhang Y,Zhu M,Xu P,Chang Y,Jia Y,Huang Y

Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans.
Archives of oral biology95149-155(2018 Nov)
Funato N,Yanagisawa H

Protein disulfide isomerase as a prosurvival factor in cell therapy for muscular and vascular diseases.
Stem cell research & therapy9(1)250(2018 09)
Di Rocco G,Baldari S,Gentile A,Capogrossi M,Toietta G

Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence.
Cell reports23(12)3565-3578(2018 06)
Kim YM,Youn SW,Sudhahar V,Das A,Chandhri R,Cuervo Grajal H,Kweon J,Leanhart S,He L,Toth PT,Kitajewski J,Rehman J,Yoon Y,Cho J,Fukai T,Ushio-Fukai M

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P4hb cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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