Mrc1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mrc1
Entrez Gene ID	17533
Full Name	mannose receptor, C type 1
Synonyms	AW259686,CD206,MR
General protein information	Preferred Names mannose receptor, C type 1 Names macrophage mannose receptor 1 MMR
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 A2\|2 10.46 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008625.2	NP_032651.2	macrophage mannose receptor 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	MRC1	NP_002429.1
Pan troglodytes (chimpanzee)	MRC1	XP_507681.2
Danio rerio (zebrafish)	mrc1a	XP_002663014.2
Bos taurus (cattle)	MRC1	XP_003586820.2
Xenopus tropicalis (tropical clawed frog)	mrc1	XP_002939048.2
Mus musculus (house mouse)	Mrc1	NP_032651.2
Rattus norvegicus (Norway rat)	Mrc1	NP_001099593.2
Gallus gallus (chicken)	LOC420516	XP_418618.2
Macaca mulatta (Rhesus monkey)	MRC1L1	XP_001091661.1
Canis lupus familiaris (dog)	MRC1	XP_005617149.1

Gene Ontology
Bibliography

Related articles in PubMed

Endocardially Derived Macrophages Are Essential for Valvular Remodeling.
Shigeta A, Huang V, Zuo J, Besada R, Nakashima Y, Lu Y, Ding Y, Pellegrini M, Kulkarni RP, Hsiai T, Deb A, Zhou B, Nakano H, Nakano A
Developmental cell48(5)617-630.e3(2019 03)

Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development.
Munro DAD, Wineberg Y, Tarnick J, Vink CS, Li Z, Pridans C, Dzierzak E, Kalisky T, Hohenstein P, Davies JA
eLife8(2019 02)

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins.
Jürgensen HJ, Nørregaard KS, Sibree MM, Santoni-Rugiu E, Madsen DH, Wassilew K, Krustrup D, Garred P, Bugge TH, Engelholm LH, Behrendt N
The Journal of cell biology218(1)333-349(2019 01)

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.
Subramanian K, Neill DR, Malak HA, Spelmink L, Khandaker S, Dalla Libera Marchiori G, Dearing E, Kirby A, Yang M, Achour A, Nilvebrant J, Nygren PÅ, Plant L, Kadioglu A, Henriques-Normark B
Nature microbiology4(1)62-70(2019 01)

Erythro-myeloid progenitors contribute endothelial cells to blood vessels.
Plein A, Fantin A, Denti L, Pollard JW, Ruhrberg C
Nature562(7726)223-228(2018 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mrc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mrc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18456	NM_008625.2 Latest version!	Mus musculus mannose receptor, C type 1 (Mrc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$727.30 $1039.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mrc1 ( NM_008625.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032651.2 Mus musculus mannose receptor, C type 1 (Mrc1), mRNA.

Price & Availability↑

CloneID	OMu18456
Clone ID Related Accession (Same CDS sequence)	NM_008625.2
Accession Version	NM_008625.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	macrophage mannose receptor 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from Z11974.1, AL845290.7, AK079897.1 and BE197931.1. On Mar 13, 2009 this sequence version replaced NM_008625.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Z11974.1, BC141338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTTC TCCTGCTTCT GGCTTTTATC TCTGTCATCC CTGTCTCTGT TCAGCTATTG 
GACGCGAGGC AATTTTTAAT CTATAATGAA GATCACAAGC GCTGCGTGGA CGCTCTAAGT 
GCCATCTCAG TTCAGACGGC AACTTGCAAC CCGGAAGCTG AATCCCAGAA ATTCCGCTGG 
GTGTCAGATT CTCAGATCAT GAGTGTTGCT TTCAAATTAT GTTTGGGAGT GCCATCAAAA 
ACTGACTGGG CTTCCGTCAC CCTGTATGCC TGTGATTCGA AAAGTGAATA TCAGAAATGG 
GAGTGTAAGA ATGACACACT CTTTGGAATC AAGGGCACAG AGTTATATTT TAATTATGGC 
AACAGACAAG AGAAGAATAT CAAGCTTTAC AAAGGTTCGG GATTGTGGAG CAGATGGAAG 
GTCTATGGAA CCACGGATGA CCTGTGCTCG AGAGGATATG AAGCCATGTA CTCCTTACTG 
GGCAATGCAA ATGGAGCCGT CTGTGCATTT CCATTCAAGT TTGAAAACAA GTGGTATGCA 
GACTGCACCT CTGCCGGGCG CTCGGACGGA TGGCTCTGGT GTGGAACCAC CACTGACTAC 
GACAAAGACA AGCTGTTTGG ATTTTGTCCA TTGCACTTTG AGGGAAGCGA GAGATTATGG 
AACAAAGATC CACTGACTGG CATTCTTTAC CAGATAAACT CCAAGTCTGC TTTAACCTGG 
CATCAGGCAA GGGCAAGCTG CAAGCAGCAG AATGCTGACC TCCTGAGTGT CACGGAGATC 
CACGAGCAAA TGTACCTCAC AGGATTAACC AGTTCCTTGA GCTCGGGACT CTGGATTGGA 
CTCAACAGTC TGAGTGTACG CAGTGGTTGG CAGTGGGCTG GAGGAAGCCC ATTCCGGTAT 
CTGAACTGGC TACCAGGAAG TCCATCATCA GAGCCTGGAA AGAGCTGTGT GTCACTAAAC 
CCTGGAAAAA ATGCCAAGTG GGAAAATCTG GAATGTGTTC AGAAGCTTGG CTACATTTGT 
AAAAAGGGAA ACAATACCTT GAACCCATTT ATCATTCCCT CAGCAAGCGA TGTGCCTACC 
GGCTGCCCTA ATCAGTGGTG GCCCTATGCA GGCCACTGCT ACAGGATCCA TAGGGAAGAG 
AAGAAGATCC AGAAATATGC TTTGCAAGCT TGTAGGAAGG AGGGTGGGGA CCTGGCAAGT 
ATCCACAGCA TTGAGGAGTT TGACTTCATC TTCTCCCAGC TCGGATATGA GCCAAATGAT 
GAGCTGTGGA TTGGTTTAAA TGACATCAAG ATTCAGATGT ACTTTGAGTG GAGTGATGGA 
ACCCCAGTGA CATTTACTAA ATGGCTTCCT GGAGAGCCAA GCCATGAGAA CAACAGACAG 
GAGGACTGCG TGGTTATGAA AGGCAAGGAT GGATACTGGG CGGACAGAGC CTGTGAGCAA 
CCACTAGGTT ACATCTGTAA GATGGTATCA CAAAGCCATG CTGTAGTACC GGAGGGTGCA 
GACAAAGGCT GCCGGAAAGG CTGGAAACGG CATGGGTTTT ACTGCTACTT GATTGGATCC 
ACTCTATCCA CCTTCACTGA TGCAAACCAC ACATGCACAA ATGAAAAGGC TTATTTAACA 
ACAGTTGAAG ACAGATATGA ACAAGCATTC CTGACTAGTT TGGTTGGATT GAGGCCTGAA 
AAATATTTTT GGACAGGACT CTCAGATGTT CAAAACAAAG GGACGTTTCG GTGGACTGTG 
GACGAGCAGG TGCAGTTTAC ACACTGGAAT GCCGACATGC CAGGACGAAA GGCGGGATGT 
GTTGCCATGA AAACCGGAGT GGCAGGTGGC TTATGGGATG TTTTGAGTTG TGAAGAAAAG 
GCAAAATTTG TGTGCAAACA TTGGGCAGAA GGAGTGACTC GCCCACCAGA GCCCACAACA 
ACTCCTGAAC CCAAATGTCC AGAAAACTGG GGTACCACCA GTAAAACCAG CATGTGTTTC 
AAACTGTATG CAAAAGGAAA GCATGAAAAG AAAACGTGGT TTGAATCTCG AGATTTTTGC 
AAAGCTATAG GTGGAGAGCT GGCGAGCATC AAGAGTAAAG ATGAACAGCA AGTGATTTGG 
AGGCTGATTA CGAGCAGTGG AAGCTACCAT GAGCTGTTTT GGTTGGGACT GACCTATGGA 
AGTCCTTCAG AGGGGTTCAC CTGGAGTGAT GGTTCTCCCG TTTCCTATGA AAATTGGGCT 
TACGGTGAAC CAAATAATTA CCAAAATGTT GAATATTGTG GTGAGCTGAA AGGTGACCCT 
GGCATGTCCT GGAATGATAT CAACTGTGAA CACCTCAACA ACTGGATTTG TCAGATACAA 
AAAGGGAAAA CACTACTACC TGAGCCCACA CCTGCTCCAC AAGACAATCC ACCAGTTACT 
GCAGATGGGT GGGTTATTTA CAAAGACTAC CAGTACTATT TTAGCAAAGA GAAGGAAACC 
ATGGACAACG CGCGAGCATT TTGCAAGAAG AATTTTGGTG ATCTTGCTAC AATTAAAAGT 
GAAAGTGAAA AGAAGTTTCT ATGGAAATAT ATAAACAAGA ATGGTGGGCA GTCACCATAT 
TTTATTGGCA TGTTAATCAG CATGGATAAG AAATTCATTT GGATGGATGG GAGCAAAGTA 
GATTTTGTGG CTTGGGCTAC AGGAGAACCC AACTTTGCAA ATGATGATGA AAACTGTGTA 
ACGATGTACA CAAATTCAGG GTTCTGGAAT GACATCAACT GTGGTTATCC AAATAACTTC 
ATCTGCCAGA GACATAACAG CAGCATCAAT GCCACTGCCA TGCCTACCAC ACCCACGACA 
CCAGGTGGCT GCAAGGAAGG TTGGCATTTG TACAAGAACA AGTGCTTTAA AATTTTTGGA 
TTTGCTAATG AAGAAAAAAA AAGCTGGCAA GACGCACGGC AAGCTTGCAA AGGACTGAAA 
GGAAACCTGG TGTCCATAGA AAATGCACAA GAGCAAGCAT TTGTTACCTA TCACATGAGA 
GACTCCACTT TCAATGCCTG GACTGGGCTG AATGATATCA ACGCAGAACA CATGTTCCTG 
TGGACAGCTG GACAAGGAGT TCATTATACA AACTGGGGGA AAGGCTATCC TGGTGGAAGA 
AGAAGTAGCC TATCTTATGA AGATGCTGAC TGTGTAGTTG TGATTGGTGG CAATTCACGA 
GAGGCAGGGA CCTGGATGGA TGACACCTGT GACAGTAAAC AAGGCTATAT ATGTCAAACA 
CAGACTGACC CTTCCCTGCC TGTTTCTCCA ACCACTACTC CAAAAGATGG CTTTGTTACA 
TATGGGAAAA GCAGCTATTC CCTTATGAAA TTGAAGCTAC CATGGCATGA AGCAGAGACA 
TATTGCAAGG ATCATACTTC CCTGCTTGCT AGCATTCTAG ACCCCTACAG TAATGCATTT 
GCATGGATGA AAATGCACCC ATTTAATGTA CCCATATGGA TTGCCCTGAA CAGCAACTTG 
ACCAATAATG AATATACTTG GACGGATAGA TGGAGGGTGC GGTACACTAA CTGGGGTGCT 
GACGAGCCGA AGCTTAAGTC AGCATGTGTT TACATGGATG TTGATGGCTA CTGGAGAACA 
TCATACTGCA ATGAAAGTTT TTATTTTCTC TGCAAAAAAT CAGACGAAAT CCCTGCTACT 
GAACCTCCTC AACTGCCTGG CAAGTGTCCA GAGTCAGAAC AGACTGCGTG GATTCCTTTC 
TATGGCCATT GCTACTATTT TGAATCTTCT TTTACGAGAA GTTGGGGTCA GGCTTCTCTG 
GAATGCCTTC GAATGGGTGC CTCCCTGGTT TCCATCGAGA CTGCTGCTGA GTCCAGTTTT 
CTGTCATACC GTGTTGAACC TCTTAAAAGT AAAACCAATT TTTGGATAGG CATGTTCCGA 
AATGTTGAAG GGAAGTGGCT TTGGTTGAAC GACAATCCTG TCTCCTTTGT CAACTGGAAA 
ACAGGCGATC CCTCTGGTGA ACGGAATGAT TGTGTAGTTC TAGCTTCATC TTCGGGCCTT 
TGGAATAATA TCCACTGTTC TTCGTACAAA GGATTTATTT GTAAAATGCC AAAAATTATT 
GATCCTGTAA CTACACACTC ATCCATTACA ACCAAAGCTG ACCAAAGGAA GATGGATCCT 
CAACCCAAGG GCTCTTCTAA AGCAGCAGGA GTGGTCACCG TGGTCCTCCT GATTGTGATA 
GGTGCCGGCG TTGCAGCCTA TTTCTTTTAT AAGAAAAGGC ATGCGTTGCA CATACCTCAA 
GAGGCCACCT TTGAAAACAC TCTCTACTTC AACAGTAATC TGAGTCCAGG AACAAGTGAC 
ACGAAAGATC TCATGGGCAA CATCGAGCAG AATGAGCATG CGATCATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032651.2
CDS	100..4470
Translation	MRLLLLLAFISVIPVSVQLLDARQFLIYNEDHKRCVDALSAISVQTATCNPEAESQKFRWVSDSQIMSVAFKLCLGVPSKTDWASVTLYACDSKSEYQKWECKNDTLFGIKGTELYFNYGNRQEKNIKLYKGSGLWSRWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDKDKLFGFCPLHFEGSERLWNKDPLTGILYQINSKSALTWHQARASCKQQNADLLSVTEIHEQMYLTGLTSSLSSGLWIGLNSLSVRSGWQWAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNNTLNPFIIPSASDVPTGCPNQWWPYAGHCYRIHREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVMKGKDGYWADRACEQPLGYICKMVSQSHAVVPEGADKGCRKGWKRHGFYCYLIGSTLSTFTDANHTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQFTHWNADMPGRKAGCVAMKTGVAGGLWDVLSCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPENWGTTSKTSMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLITSSGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDYQYYFSKEKETMDNARAFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGMLISMDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNSSINATAMPTTPTTPGGCKEGWHLYKNKCFKIFGFANEEKKSWQDARQACKGLKGNLVSIENAQEQAFVTYHMRDSTFNAWTGLNDINAEHMFLWTAGQGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNSREAGTWMDDTCDSKQGYICQTQTDPSLPVSPTTTPKDGFVTYGKSSYSLMKLKLPWHEAETYCKDHTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLTNNEYTWTDRWRVRYTNWGADEPKLKSACVYMDVDGYWRTSYCNESFYFLCKKSDEIPATEPPQLPGKCPESEQTAWIPFYGHCYYFESSFTRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGMFRNVEGKWLWLNDNPVSFVNWKTGDPSGERNDCVVLASSSGLWNNIHCSSYKGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVTVVLLIVIGAGVAAYFFYKKRHALHIPQEATFENTLYFNSNLSPGTSDTKDLMGNIEQNEHAII

Target ORF information:

RefSeq Version	NM_008625.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus mannose receptor, C type 1 (Mrc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008625.2

ORF Insert Sequence:

ATGAGGCTTC TCCTGCTTCT GGCTTTTATC TCTGTCATCC CTGTCTCTGT TCAGCTATTG 
GACGCGAGGC AATTTTTAAT CTATAATGAA GATCACAAGC GCTGCGTGGA CGCTCTAAGT 
GCCATCTCAG TTCAGACGGC AACTTGCAAC CCGGAAGCTG AATCCCAGAA ATTCCGCTGG 
GTGTCAGATT CTCAGATCAT GAGTGTTGCT TTCAAATTAT GTTTGGGAGT GCCATCAAAA 
ACTGACTGGG CTTCCGTCAC CCTGTATGCC TGTGATTCGA AAAGTGAATA TCAGAAATGG 
GAGTGTAAGA ATGACACACT CTTTGGAATC AAGGGCACAG AGTTATATTT TAATTATGGC 
AACAGACAAG AGAAGAATAT CAAGCTTTAC AAAGGTTCGG GATTGTGGAG CAGATGGAAG 
GTCTATGGAA CCACGGATGA CCTGTGCTCG AGAGGATATG AAGCCATGTA CTCCTTACTG 
GGCAATGCAA ATGGAGCCGT CTGTGCATTT CCATTCAAGT TTGAAAACAA GTGGTATGCA 
GACTGCACCT CTGCCGGGCG CTCGGACGGA TGGCTCTGGT GTGGAACCAC CACTGACTAC 
GACAAAGACA AGCTGTTTGG ATTTTGTCCA TTGCACTTTG AGGGAAGCGA GAGATTATGG 
AACAAAGATC CACTGACTGG CATTCTTTAC CAGATAAACT CCAAGTCTGC TTTAACCTGG 
CATCAGGCAA GGGCAAGCTG CAAGCAGCAG AATGCTGACC TCCTGAGTGT CACGGAGATC 
CACGAGCAAA TGTACCTCAC AGGATTAACC AGTTCCTTGA GCTCGGGACT CTGGATTGGA 
CTCAACAGTC TGAGTGTACG CAGTGGTTGG CAGTGGGCTG GAGGAAGCCC ATTCCGGTAT 
CTGAACTGGC TACCAGGAAG TCCATCATCA GAGCCTGGAA AGAGCTGTGT GTCACTAAAC 
CCTGGAAAAA ATGCCAAGTG GGAAAATCTG GAATGTGTTC AGAAGCTTGG CTACATTTGT 
AAAAAGGGAA ACAATACCTT GAACCCATTT ATCATTCCCT CAGCAAGCGA TGTGCCTACC 
GGCTGCCCTA ATCAGTGGTG GCCCTATGCA GGCCACTGCT ACAGGATCCA TAGGGAAGAG 
AAGAAGATCC AGAAATATGC TTTGCAAGCT TGTAGGAAGG AGGGTGGGGA CCTGGCAAGT 
ATCCACAGCA TTGAGGAGTT TGACTTCATC TTCTCCCAGC TCGGATATGA GCCAAATGAT 
GAGCTGTGGA TTGGTTTAAA TGACATCAAG ATTCAGATGT ACTTTGAGTG GAGTGATGGA 
ACCCCAGTGA CATTTACTAA ATGGCTTCCT GGAGAGCCAA GCCATGAGAA CAACAGACAG 
GAGGACTGCG TGGTTATGAA AGGCAAGGAT GGATACTGGG CGGACAGAGC CTGTGAGCAA 
CCACTAGGTT ACATCTGTAA GATGGTATCA CAAAGCCATG CTGTAGTACC GGAGGGTGCA 
GACAAAGGCT GCCGGAAAGG CTGGAAACGG CATGGGTTTT ACTGCTACTT GATTGGATCC 
ACTCTATCCA CCTTCACTGA TGCAAACCAC ACATGCACAA ATGAAAAGGC TTATTTAACA 
ACAGTTGAAG ACAGATATGA ACAAGCATTC CTGACTAGTT TGGTTGGATT GAGGCCTGAA 
AAATATTTTT GGACAGGACT CTCAGATGTT CAAAACAAAG GGACGTTTCG GTGGACTGTG 
GACGAGCAGG TGCAGTTTAC ACACTGGAAT GCCGACATGC CAGGACGAAA GGCGGGATGT 
GTTGCCATGA AAACCGGAGT GGCAGGTGGC TTATGGGATG TTTTGAGTTG TGAAGAAAAG 
GCAAAATTTG TGTGCAAACA TTGGGCAGAA GGAGTGACTC GCCCACCAGA GCCCACAACA 
ACTCCTGAAC CCAAATGTCC AGAAAACTGG GGTACCACCA GTAAAACCAG CATGTGTTTC 
AAACTGTATG CAAAAGGAAA GCATGAAAAG AAAACGTGGT TTGAATCTCG AGATTTTTGC 
AAAGCTATAG GTGGAGAGCT GGCGAGCATC AAGAGTAAAG ATGAACAGCA AGTGATTTGG 
AGGCTGATTA CGAGCAGTGG AAGCTACCAT GAGCTGTTTT GGTTGGGACT GACCTATGGA 
AGTCCTTCAG AGGGGTTCAC CTGGAGTGAT GGTTCTCCCG TTTCCTATGA AAATTGGGCT 
TACGGTGAAC CAAATAATTA CCAAAATGTT GAATATTGTG GTGAGCTGAA AGGTGACCCT 
GGCATGTCCT GGAATGATAT CAACTGTGAA CACCTCAACA ACTGGATTTG TCAGATACAA 
AAAGGGAAAA CACTACTACC TGAGCCCACA CCTGCTCCAC AAGACAATCC ACCAGTTACT 
GCAGATGGGT GGGTTATTTA CAAAGACTAC CAGTACTATT TTAGCAAAGA GAAGGAAACC 
ATGGACAACG CGCGAGCATT TTGCAAGAAG AATTTTGGTG ATCTTGCTAC AATTAAAAGT 
GAAAGTGAAA AGAAGTTTCT ATGGAAATAT ATAAACAAGA ATGGTGGGCA GTCACCATAT 
TTTATTGGCA TGTTAATCAG CATGGATAAG AAATTCATTT GGATGGATGG GAGCAAAGTA 
GATTTTGTGG CTTGGGCTAC AGGAGAACCC AACTTTGCAA ATGATGATGA AAACTGTGTA 
ACGATGTACA CAAATTCAGG GTTCTGGAAT GACATCAACT GTGGTTATCC AAATAACTTC 
ATCTGCCAGA GACATAACAG CAGCATCAAT GCCACTGCCA TGCCTACCAC ACCCACGACA 
CCAGGTGGCT GCAAGGAAGG TTGGCATTTG TACAAGAACA AGTGCTTTAA AATTTTTGGA 
TTTGCTAATG AAGAAAAAAA AAGCTGGCAA GACGCACGGC AAGCTTGCAA AGGACTGAAA 
GGAAACCTGG TGTCCATAGA AAATGCACAA GAGCAAGCAT TTGTTACCTA TCACATGAGA 
GACTCCACTT TCAATGCCTG GACTGGGCTG AATGATATCA ACGCAGAACA CATGTTCCTG 
TGGACAGCTG GACAAGGAGT TCATTATACA AACTGGGGGA AAGGCTATCC TGGTGGAAGA 
AGAAGTAGCC TATCTTATGA AGATGCTGAC TGTGTAGTTG TGATTGGTGG CAATTCACGA 
GAGGCAGGGA CCTGGATGGA TGACACCTGT GACAGTAAAC AAGGCTATAT ATGTCAAACA 
CAGACTGACC CTTCCCTGCC TGTTTCTCCA ACCACTACTC CAAAAGATGG CTTTGTTACA 
TATGGGAAAA GCAGCTATTC CCTTATGAAA TTGAAGCTAC CATGGCATGA AGCAGAGACA 
TATTGCAAGG ATCATACTTC CCTGCTTGCT AGCATTCTAG ACCCCTACAG TAATGCATTT 
GCATGGATGA AAATGCACCC ATTTAATGTA CCCATATGGA TTGCCCTGAA CAGCAACTTG 
ACCAATAATG AATATACTTG GACGGATAGA TGGAGGGTGC GGTACACTAA CTGGGGTGCT 
GACGAGCCGA AGCTTAAGTC AGCATGTGTT TACATGGATG TTGATGGCTA CTGGAGAACA 
TCATACTGCA ATGAAAGTTT TTATTTTCTC TGCAAAAAAT CAGACGAAAT CCCTGCTACT 
GAACCTCCTC AACTGCCTGG CAAGTGTCCA GAGTCAGAAC AGACTGCGTG GATTCCTTTC 
TATGGCCATT GCTACTATTT TGAATCTTCT TTTACGAGAA GTTGGGGTCA GGCTTCTCTG 
GAATGCCTTC GAATGGGTGC CTCCCTGGTT TCCATCGAGA CTGCTGCTGA GTCCAGTTTT 
CTGTCATACC GTGTTGAACC TCTTAAAAGT AAAACCAATT TTTGGATAGG CATGTTCCGA 
AATGTTGAAG GGAAGTGGCT TTGGTTGAAC GACAATCCTG TCTCCTTTGT CAACTGGAAA 
ACAGGCGATC CCTCTGGTGA ACGGAATGAT TGTGTAGTTC TAGCTTCATC TTCGGGCCTT 
TGGAATAATA TCCACTGTTC TTCGTACAAA GGATTTATTT GTAAAATGCC AAAAATTATT 
GATCCTGTAA CTACACACTC ATCCATTACA ACCAAAGCTG ACCAAAGGAA GATGGATCCT 
CAACCCAAGG GCTCTTCTAA AGCAGCAGGA GTGGTCACCG TGGTCCTCCT GATTGTGATA 
GGTGCCGGCG TTGCAGCCTA TTTCTTTTAT AAGAAAAGGC ATGCGTTGCA CATACCTCAA 
GAGGCCACCT TTGAAAACAC TCTCTACTTC AACAGTAATC TGAGTCCAGG AACAAGTGAC 
ACGAAAGATC TCATGGGCAA CATCGAGCAG AATGAGCATG CGATCATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Endocardially Derived Macrophages Are Essential for Valvular Remodeling.
Developmental cell48(5)617-630.e3(2019 03)
Shigeta A,Huang V,Zuo J,Besada R,Nakashima Y,Lu Y,Ding Y,Pellegrini M,Kulkarni RP,Hsiai T,Deb A,Zhou B,Nakano H,Nakano A

Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development.
eLife8(2019 02)
Munro DAD,Wineberg Y,Tarnick J,Vink CS,Li Z,Pridans C,Dzierzak E,Kalisky T,Hohenstein P,Davies JA

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins.
The Journal of cell biology218(1)333-349(2019 01)
Jürgensen HJ,Nørregaard KS,Sibree MM,Santoni-Rugiu E,Madsen DH,Wassilew K,Krustrup D,Garred P,Bugge TH,Engelholm LH,Behrendt N

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.
Nature microbiology4(1)62-70(2019 01)
Subramanian K,Neill DR,Malak HA,Spelmink L,Khandaker S,Dalla Libera Marchiori G,Dearing E,Kirby A,Yang M,Achour A,Nilvebrant J,Nygren PÅ,Plant L,Kadioglu A,Henriques-Normark B

Erythro-myeloid progenitors contribute endothelial cells to blood vessels.
Nature562(7726)223-228(2018 10)
Plein A,Fantin A,Denti L,Pollard JW,Ruhrberg C

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Mrc1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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