Kif5c cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kif5c
Entrez Gene ID	16574
Full Name	kinesin family member 5C
Synonyms	KINN,Khc,NKHC,NKHC2
General protein information	Preferred Names kinesin family member 5C Names kinesin heavy chain isoform 5C kinesin heavy chain member 5C kinesin heavy chain neuron-specific 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 C1.1\|2 28.68 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008449.2	NP_032475.2	kinesin heavy chain isoform 5C
NM_008449.3	NP_032475.2	kinesin heavy chain isoform 5C

Pathways from BioSystems

Homologies

Bos taurus (cattle)	KIF5C	NP_001069595.2
Rattus norvegicus (Norway rat)	Kif5c	NP_001101200.1
Canis lupus familiaris (dog)	KIF5C	XP_533351.3
Pan troglodytes (chimpanzee)	KIF5C	XP_525938.3
Macaca mulatta (Rhesus monkey)	KIF5C	XP_001082054.2
Mus musculus (house mouse)	Kif5c	NP_032475.2
Gallus gallus (chicken)	KIF5C	XP_422155.2
Danio rerio (zebrafish)	kif5c	NP_001116747.1
Xenopus tropicalis (tropical clawed frog)	kif5c	XP_002935337.2
Homo sapiens (human)	KIF5C	NP_004513.1

Gene Ontology
Bibliography

Related articles in PubMed

Investigating role of conformational changes of microtubule in regulating its binding affinity to kinesin by all-atom molecular dynamics simulation.
Shi XX, Fu YB, Guo SK, Wang PY, Chen H, Xie P
Proteins86(11)1127-1139(2018 11)

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.
DuRaine G, Wisner TW, Howard P, Johnson DC
Journal of virology92(20)(2018 10)

SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion.
Chen Q, Hao W, Xiao C, Wang R, Xu X, Lu H, Chen W, Deng CX
Cell reports18(13)3155-3166(2017 03)

X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding.
Morikawa M, Yajima H, Nitta R, Inoue S, Ogura T, Sato C, Hirokawa N
The EMBO journal34(9)1270-86(2015 May)

Analysis of Kif5b expression during mouse kidney development.
Cui J, Li X, Duan Z, Xue W, Wang Z, Lu S, Lin R, Liu M, Zhu G, Huang JD
PloS one10(4)e0126002(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kif5c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kif5c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu01946	NM_008449.3 Latest version!	Mus musculus kinesin family member 5C (Kif5c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$475.30 $679.00
View Old Accession Versions >>
OMu01946	NM_008449.2	Mus musculus kinesin family member 5C (Kif5c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kif5c ( NM_008449.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032475.2 Mus musculus kinesin family member 5C (Kif5c), mRNA.

Price & Availability↑

CloneID	OMu01946
Clone ID Related Accession (Same CDS sequence)	NM_008449.2 , NM_008449.3
Accession Version	NM_008449.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2871bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514217600000
Organism	Mus musculus(house mouse)
Product	kinesin heavy chain isoform 5C
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC067051.1. On Mar 14, 2004 this sequence version replaced NM_008449.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC067051.1, SRR1660811.109669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCGGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTGCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC AAAGCAGATT GTCAAAGATG TCCTTGAGGG TTATAATGGA 
ACAATTTTTG CATATGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGTTA 
CATGATCCTC AGCTTATGGG TATCATTCCA AGGATTGCAC ATGATATTTT TGATCACATC 
TATTCCATGG ACGAGAACCT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGATGTGTCC AAGACCAACT TGGCAGTTCA TGAAGACAAA 
AACAGAGTCC CCTATGTAAA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACACGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCTA GGAGTCACAG TATCTTCCTG ATTAACATTA AGCAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACCGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATTTC TGCCTTGGCA GAAGGGACAA AAACACATGT ACCGTACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGTAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAAGCCGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAGTGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAACA AGGCCTTGAA GAGTGTCCTC 
CAGCATCTGG AGATGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTACC CGAGGACGAA 
CAGATCAGCG CCAAGGACCA GAAGAGCCTA GAGCCCTGTG ACAACACACC CATCATAGAC 
AACATCACGC CTGTTGTGGA CGGCATCTCT GCCGAGAAGG AGAAGTATGA CGAGGAGATC 
ACCAGTTTGT ACCGACAGCT CGATGATAAG GATGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGATGAGC TCCTGGCTTC CACGAGAAGG 
GACTATGAGA AGATCCAGGA GGAGCTGACA CGCCTCCAGA TCGAAAATGA GGCAGCTAAA 
GACGAAGTGA AAGAAGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAAGAAG TGGAGGACAA GACCAGGGCC AACGAGCAAC TGACTGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGA GAGCTGAGTC AGCTGCAAGA GCTTAGTAAC 
CACCAGAAAA AGAGGGCCAC AGAGATCCTG AACCTGCTTC TCAAGGACCT GGGGGAGATA 
GGCGGAATTA TTGGCACCAA CGATGTGAAG ACTCTGGCAG ATGTGAACGG GGTCATTGAG 
GAGGAGTTCA CCATGGCACG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGTGCC CAGATGGACT CTAACAGGAA GATGAACGCC 
AGTGAGCGCG AGCTGGCAGC GTGCCAGTTG CTTATCTCAC AGCACGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCCCAG 
GACTCCCTCA GCGAGGAACT GGCCAAGCTC CGGGCCCAGG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA GGTGAAGAAA 
GCTCTGGAGC AGCAGATGGA GAGCCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGCGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TCCGGGATTT GAATCAGAAA 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAACTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGGGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA GGAGACTGTG TCTAGAGAAC TCCAGACCCT TCATAACCTG 
CGCAAACTCT TCGTCCAGGA TTTGACAACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGCAGCGC TGCTCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAACAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCAGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTTCGTGCT ACCGCAGAAC GCGTCAAGGC CTTGGAGAGT 
GCGCTGAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AACGCTACCA GCAGGAAGTA 
GATCGCATCA AGGAGGCTGT GCGAGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGCCATTAC CCAGCATCAT CTCCGACAGC TGTCCATGCC 
GTCCGAGGAG GAGGAGGTGG CTCTTCAAAC TCTACTCACT ACCAGAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032475.2
CDS	349..3219
Translation	MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVLQHLEMELNRWRNGEAVPEDEQISAKDQKSLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGGSSNSTHYQK

Target ORF information:

RefSeq Version	NM_008449.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus kinesin family member 5C (Kif5c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008449.2

ORF Insert Sequence:

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCGGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTGCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC AAAGCAGATT GTCAAAGATG TCCTTGAGGG TTATAATGGA 
ACAATTTTTG CATATGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGTTA 
CATGATCCTC AGCTTATGGG TATCATTCCA AGGATTGCAC ATGATATTTT TGATCACATC 
TATTCCATGG ACGAGAACCT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGATGTGTCC AAGACCAACT TGGCAGTTCA TGAAGACAAA 
AACAGAGTCC CCTATGTAAA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACACGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCTA GGAGTCACAG TATCTTCCTG ATTAACATTA AGCAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACCGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATTTC TGCCTTGGCA GAAGGGACAA AAACACATGT ACCGTACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGTAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAAGCCGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAGTGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAACA AGGCCTTGAA GAGTGTCCTC 
CAGCATCTGG AGATGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTACC CGAGGACGAA 
CAGATCAGCG CCAAGGACCA GAAGAGCCTA GAGCCCTGTG ACAACACACC CATCATAGAC 
AACATCACGC CTGTTGTGGA CGGCATCTCT GCCGAGAAGG AGAAGTATGA CGAGGAGATC 
ACCAGTTTGT ACCGACAGCT CGATGATAAG GATGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGATGAGC TCCTGGCTTC CACGAGAAGG 
GACTATGAGA AGATCCAGGA GGAGCTGACA CGCCTCCAGA TCGAAAATGA GGCAGCTAAA 
GACGAAGTGA AAGAAGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAAGAAG TGGAGGACAA GACCAGGGCC AACGAGCAAC TGACTGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGA GAGCTGAGTC AGCTGCAAGA GCTTAGTAAC 
CACCAGAAAA AGAGGGCCAC AGAGATCCTG AACCTGCTTC TCAAGGACCT GGGGGAGATA 
GGCGGAATTA TTGGCACCAA CGATGTGAAG ACTCTGGCAG ATGTGAACGG GGTCATTGAG 
GAGGAGTTCA CCATGGCACG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGTGCC CAGATGGACT CTAACAGGAA GATGAACGCC 
AGTGAGCGCG AGCTGGCAGC GTGCCAGTTG CTTATCTCAC AGCACGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCCCAG 
GACTCCCTCA GCGAGGAACT GGCCAAGCTC CGGGCCCAGG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA GGTGAAGAAA 
GCTCTGGAGC AGCAGATGGA GAGCCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGCGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TCCGGGATTT GAATCAGAAA 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAACTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGGGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA GGAGACTGTG TCTAGAGAAC TCCAGACCCT TCATAACCTG 
CGCAAACTCT TCGTCCAGGA TTTGACAACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGCAGCGC TGCTCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAACAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCAGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTTCGTGCT ACCGCAGAAC GCGTCAAGGC CTTGGAGAGT 
GCGCTGAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AACGCTACCA GCAGGAAGTA 
GATCGCATCA AGGAGGCTGT GCGAGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGCCATTAC CCAGCATCAT CTCCGACAGC TGTCCATGCC 
GTCCGAGGAG GAGGAGGTGG CTCTTCAAAC TCTACTCACT ACCAGAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kif5c ( NM_008449.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032475.2 Mus musculus kinesin family member 5C (Kif5c), mRNA.

Price & Availability↑

CloneID	OMu01946
Clone ID Related Accession (Same CDS sequence)	NM_008449.2 , NM_008449.3
Accession Version	NM_008449.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2871bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571760000000
Organism	Mus musculus(house mouse)
Product	kinesin heavy chain isoform 5C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ113909.1 and BC067051.1. On Apr 24, 2018 this sequence version replaced NM_008449.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC067051.1, SRR1660811.109669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCGGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTGCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC AAAGCAGATT GTCAAAGATG TCCTTGAGGG TTATAATGGA 
ACAATTTTTG CATATGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGTTA 
CATGATCCTC AGCTTATGGG TATCATTCCA AGGATTGCAC ATGATATTTT TGATCACATC 
TATTCCATGG ACGAGAACCT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGATGTGTCC AAGACCAACT TGGCAGTTCA TGAAGACAAA 
AACAGAGTCC CCTATGTAAA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACACGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCTA GGAGTCACAG TATCTTCCTG ATTAACATTA AGCAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACCGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATTTC TGCCTTGGCA GAAGGGACAA AAACACATGT ACCGTACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGTAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAAGCCGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAGTGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAACA AGGCCTTGAA GAGTGTCCTC 
CAGCATCTGG AGATGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTACC CGAGGACGAA 
CAGATCAGCG CCAAGGACCA GAAGAGCCTA GAGCCCTGTG ACAACACACC CATCATAGAC 
AACATCACGC CTGTTGTGGA CGGCATCTCT GCCGAGAAGG AGAAGTATGA CGAGGAGATC 
ACCAGTTTGT ACCGACAGCT CGATGATAAG GATGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGATGAGC TCCTGGCTTC CACGAGAAGG 
GACTATGAGA AGATCCAGGA GGAGCTGACA CGCCTCCAGA TCGAAAATGA GGCAGCTAAA 
GACGAAGTGA AAGAAGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAAGAAG TGGAGGACAA GACCAGGGCC AACGAGCAAC TGACTGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGA GAGCTGAGTC AGCTGCAAGA GCTTAGTAAC 
CACCAGAAAA AGAGGGCCAC AGAGATCCTG AACCTGCTTC TCAAGGACCT GGGGGAGATA 
GGCGGAATTA TTGGCACCAA CGATGTGAAG ACTCTGGCAG ATGTGAACGG GGTCATTGAG 
GAGGAGTTCA CCATGGCACG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGTGCC CAGATGGACT CTAACAGGAA GATGAACGCC 
AGTGAGCGCG AGCTGGCAGC GTGCCAGTTG CTTATCTCAC AGCACGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCCCAG 
GACTCCCTCA GCGAGGAACT GGCCAAGCTC CGGGCCCAGG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA GGTGAAGAAA 
GCTCTGGAGC AGCAGATGGA GAGCCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGCGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TCCGGGATTT GAATCAGAAA 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAACTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGGGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA GGAGACTGTG TCTAGAGAAC TCCAGACCCT TCATAACCTG 
CGCAAACTCT TCGTCCAGGA TTTGACAACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGCAGCGC TGCTCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAACAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCAGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTTCGTGCT ACCGCAGAAC GCGTCAAGGC CTTGGAGAGT 
GCGCTGAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AACGCTACCA GCAGGAAGTA 
GATCGCATCA AGGAGGCTGT GCGAGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGCCATTAC CCAGCATCAT CTCCGACAGC TGTCCATGCC 
GTCCGAGGAG GAGGAGGTGG CTCTTCAAAC TCTACTCACT ACCAGAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032475.2
CDS	377..3247
Translation	MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVLQHLEMELNRWRNGEAVPEDEQISAKDQKSLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGGSSNSTHYQK

Target ORF information:

RefSeq Version	NM_008449.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus kinesin family member 5C (Kif5c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008449.3

ORF Insert Sequence:

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCGGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTGCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC AAAGCAGATT GTCAAAGATG TCCTTGAGGG TTATAATGGA 
ACAATTTTTG CATATGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGTTA 
CATGATCCTC AGCTTATGGG TATCATTCCA AGGATTGCAC ATGATATTTT TGATCACATC 
TATTCCATGG ACGAGAACCT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGATGTGTCC AAGACCAACT TGGCAGTTCA TGAAGACAAA 
AACAGAGTCC CCTATGTAAA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACACGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCTA GGAGTCACAG TATCTTCCTG ATTAACATTA AGCAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACCGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATTTC TGCCTTGGCA GAAGGGACAA AAACACATGT ACCGTACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGTAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAAGCCGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAGTGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAACA AGGCCTTGAA GAGTGTCCTC 
CAGCATCTGG AGATGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTACC CGAGGACGAA 
CAGATCAGCG CCAAGGACCA GAAGAGCCTA GAGCCCTGTG ACAACACACC CATCATAGAC 
AACATCACGC CTGTTGTGGA CGGCATCTCT GCCGAGAAGG AGAAGTATGA CGAGGAGATC 
ACCAGTTTGT ACCGACAGCT CGATGATAAG GATGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGATGAGC TCCTGGCTTC CACGAGAAGG 
GACTATGAGA AGATCCAGGA GGAGCTGACA CGCCTCCAGA TCGAAAATGA GGCAGCTAAA 
GACGAAGTGA AAGAAGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAAGAAG TGGAGGACAA GACCAGGGCC AACGAGCAAC TGACTGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGA GAGCTGAGTC AGCTGCAAGA GCTTAGTAAC 
CACCAGAAAA AGAGGGCCAC AGAGATCCTG AACCTGCTTC TCAAGGACCT GGGGGAGATA 
GGCGGAATTA TTGGCACCAA CGATGTGAAG ACTCTGGCAG ATGTGAACGG GGTCATTGAG 
GAGGAGTTCA CCATGGCACG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGTGCC CAGATGGACT CTAACAGGAA GATGAACGCC 
AGTGAGCGCG AGCTGGCAGC GTGCCAGTTG CTTATCTCAC AGCACGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCCCAG 
GACTCCCTCA GCGAGGAACT GGCCAAGCTC CGGGCCCAGG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA GGTGAAGAAA 
GCTCTGGAGC AGCAGATGGA GAGCCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGCGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TCCGGGATTT GAATCAGAAA 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAACTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGGGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA GGAGACTGTG TCTAGAGAAC TCCAGACCCT TCATAACCTG 
CGCAAACTCT TCGTCCAGGA TTTGACAACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGCAGCGC TGCTCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAACAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCAGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTTCGTGCT ACCGCAGAAC GCGTCAAGGC CTTGGAGAGT 
GCGCTGAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AACGCTACCA GCAGGAAGTA 
GATCGCATCA AGGAGGCTGT GCGAGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGCCATTAC CCAGCATCAT CTCCGACAGC TGTCCATGCC 
GTCCGAGGAG GAGGAGGTGG CTCTTCAAAC TCTACTCACT ACCAGAAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Investigating role of conformational changes of microtubule in regulating its binding affinity to kinesin by all-atom molecular dynamics simulation.
Proteins86(11)1127-1139(2018 11)
Shi XX,Fu YB,Guo SK,Wang PY,Chen H,Xie P

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.
Journal of virology92(20)(2018 10)
DuRaine G,Wisner TW,Howard P,Johnson DC

SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion.
Cell reports18(13)3155-3166(2017 03)
Chen Q,Hao W,Xiao C,Wang R,Xu X,Lu H,Chen W,Deng CX

X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding.
The EMBO journal34(9)1270-86(2015 May)
Morikawa M,Yajima H,Nitta R,Inoue S,Ogura T,Sato C,Hirokawa N

Analysis of Kif5b expression during mouse kidney development.
PloS one10(4)e0126002(2015)
Cui J,Li X,Duan Z,Xue W,Wang Z,Lu S,Lin R,Liu M,Zhu G,Huang JD

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Kif5c cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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