Kif3b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kif3b
Entrez Gene ID	16569
Full Name	kinesin family member 3B
Synonyms	AI854312,AW549267,mKIAA0359
General protein information	Preferred Names kinesin family member 3B Names kinesin-like protein KIF3B microtubule plus end-directed kinesin motor 3B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 H1\|2 75.41 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008444.4	NP_032470.3	kinesin-like protein KIF3B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Kif3b	NP_032470.3
Xenopus tropicalis (tropical clawed frog)	kif3b	XP_004918676.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010396	XP_311552.4
Danio rerio (zebrafish)	kif3b	NP_001093615.1
Homo sapiens (human)	KIF3B	NP_004789.1
Macaca mulatta (Rhesus monkey)	KIF3B	XP_001108420.1
Bos taurus (cattle)	KIF3B	NP_001104258.1
Gallus gallus (chicken)	KIF3B	NP_001012852.1
Caenorhabditis elegans (roundworm)	klp-11	NP_741473.1
Pan troglodytes (chimpanzee)	KIF3B	XP_001155482.1
Canis lupus familiaris (dog)	KIF3B	XP_005634978.1
Rattus norvegicus (Norway rat)	Kif3b	NP_001099999.1
Drosophila melanogaster (fruit fly)	Klp68D	NP_001261726.1

Gene Ontology
Bibliography

Related articles in PubMed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.
Perez-Garcia V, Fineberg E, Wilson R, Murray A, Mazzeo CI, Tudor C, Sienerth A, White JK, Tuck E, Ryder EJ, Gleeson D, Siragher E, Wardle-Jones H, Staudt N, Wali N, Collins J, Geyer S, Busch-Nentwich EM, Galli A, Smith JC, Robertson E, Adams DJ, Weninger WJ, Mohun T, Hemberger M
Nature555(7697)463-468(2018 03)

Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.
Albracht CD, Guzik-Lendrum S, Rayment I, Gilbert SP
The Journal of biological chemistry291(44)23248-23256(2016 10)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.
Guzik-Lendrum S, Rank KC, Bensel BM, Taylor KC, Rayment I, Gilbert SP
Biophysical journal109(7)1472-82(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kif3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kif3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01933	NM_008444.4 Latest version!	Mus musculus kinesin family member 3B (Kif3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kif3b ( NM_008444.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032470.3 Mus musculus kinesin family member 3B (Kif3b), mRNA.

Price & Availability↑

CloneID	OMu01933
Clone ID Related Accession (Same CDS sequence)	NM_008444.4
Accession Version	NM_008444.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2244bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Mus musculus(house mouse)
Product	kinesin-like protein KIF3B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ089315.1, AK147467.1 and BC065132.1. On Apr 28, 2009 this sequence version replaced NM_008444.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147467.1, AK122258.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAAGT TAAAAAGCTC AGAATCAGTC CGGGTGGTGG TCCGCTGTCG GCCCATGAAT 
GGCAAAGAAA AGGCTGCATC TTATGACAAG GTGGTAGATG TGGATGTGAA GCTGGGGCAG 
GTGTCTGTGA AGAACCCCAA AGGCACATCC CATGAGATGC CCAAGACCTT CACCTTCGAC 
GCTGTGTATG ATTGGAACGC CAAGCAGTTT GAGCTCTATG ATGAGACGTT CCGACCACTC 
GTGGACTCTG TGCTGCAGGG TTTCAATGGC ACAATTTTTG CCTATGGACA AACAGGAACT 
GGGAAAACCT ATACCATGGA GGGAGTTCGT GGTGACCCTG AAAAAAGAGG GGTCATCCCC 
AACTCCTTTG ATCACATCTT CACCCACATC TCTCGATCTC AGAATCAGCA GTACCTGGTC 
CGGGCGTCTT ACTTAGAGAT CTATCAAGAA GAGATTCGAG ACTTGCTTTC AAAGGATCAG 
ACCAAAAGGC TAGAGCTCAA AGAGAGACCA GATACAGGAG TGTATGTAAA GGATTTGTCT 
TCTTTTGTCA CGAAGAGTGT GAAGGAGATA GAGCATGTGA TGAATGTGGG AAACCAGAAC 
CGGTCTGTCG GTGCTACAAA CATGAATGAG CACAGCTCAC GGTCGCATGC AATCTTTGTT 
ATCACTATTG AATGCAGCGA GGTGGGCCTG GATGGTGAAA ACCACATCCG GGTAGGAAAG 
CTGAATCTTG TAGATCTTGC TGGCAGTGAG CGGCAAGCCA AGACTGGAGC TCAAGGGGAA 
AGACTGAAGG AAGCCACCAA GATCAACCTG TCCCTTTCCG CCTTGGGTAA TGTTATCTCT 
GCCCTTGTAG ATGGCAAAAG CACCCATATT CCATATAGAG ACTCAAAGCT GACCAGGCTT 
CTCCAAGATT CCCTTGGTGG CAATGCCAAA ACTGTGATGG TAGCCAATGT GGGGCCTGCC 
TCTTACAATG TAGAAGAGAC CCTGACCACT CTGAGATATG CCAACCGTGC CAAAAACATT 
AAGAACAAGC CAAGGGTCAA TGAGGACCCA AAGGATGCTC TGCTTCGAGA ATTCCAAGAA 
GAAATTGCTC GGCTCAAGGC CCAGCTGGAA AAACGTTCCA TTGGCAGGAG GAAGAGGCGA 
GAGAAGCGGA GGGAAGGTGG TGGCAGTGGT GGGGGTGGGG AAGAGGAGGA GGAGGAGGGA 
GAAGAGGGTG AGGAGGACGG GGATGATAAG GATGATTACT GGCGGGAACA GCAAGAAAAA 
CTGGAGATTG AGAAGCGGGC CATTGTAGAG GACCACAGCT TGGTTGCAGA GGAGAAGATG 
AGGCTGCTGA AGGAGAAGGA GAAAAAGATG GAGGACCTGC GGCGAGAGAA GGATGCTGCA 
GAGATGCTGG GTGCCAAAAT CAAGGCCATG GAGAGTAAGC TGCTTGTCGG AGGAAAAAAT 
ATAGTAGATC ATACAAACGA ACAGCAGAAG ATCCTGGAGC AAAAACGCCA GGAGATCGCA 
GAGCAGAAAC GTCGAGAAAG AGAAATCCAG CAGCAAATGG AGAGTCGAGA TGAGGAGACC 
CTGGAACTGA AAGAGACTTA CACCTCACTG CAGCAGGAGG TAGACATCAA GACCAAAAAG 
CTCAAAAAGC TCTTTTCCAA GCTTCAGGCC GTGAAGGCCG AGATCCACGA CCTCCAAGAA 
GAACACATCA AAGAGCGCCA GGAGCTGGAG CAGACGCAGA ATGAACTCAC CCGGGAGCTA 
AAGCTCAAGC ATCTTATTAT AGAAAACTTT ATTCCCTTGG AAGAGAAGAA TAAAATTATG 
AATAGATCCT TTTTTGATGA TGAAGAAGAC CATTGGAAAT TACATCCTAT AACCAGACTG 
GAAAACCAGC AGATGATGAA GCGGCCTGTC TCTGCTGTGG GATACAAGAG ACCTCTGAGC 
CAGCATGCAC GGATGTCCAT GATGATTCGG CCAGAGCCCC GGTACAGGGC GGAGAACATC 
ATGCTCTTGG AGTTAGATAT GCCCAGCCGG ACAACCAGAG ACTACGAGGG CCCAGCCATC 
TCTCCCAAGG TTCAGGCTGC GCTGGATGCA GCTCTGCAGG ATGAAGATGA GATACAGGTG 
GATGCCTCAT CCTTTGAAAG TACTGCCAGC AGAAAACCCA AGGCCAGGCC CAAGAGTGGC 
AGGAAATCAG GATCCTCCTC TTCCTCCTCA GGAAACCCTG CATCTCAGTT TTACCCACAG 
TCTCGGGGGC TGGTTCCCAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032470.3
CDS	154..2397
Translation	MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTSHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEDGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKNKIMNRSFFDDEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEPRYRAENIMLLELDMPSRTTRDYEGPAISPKVQAALDAALQDEDEIQVDASSFESTASRKPKARPKSGRKSGSSSSSSGNPASQFYPQSRGLVPK

Target ORF information:

RefSeq Version	NM_008444.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus kinesin family member 3B (Kif3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008444.4

ORF Insert Sequence:

ATGTCCAAGT TAAAAAGCTC AGAATCAGTC CGGGTGGTGG TCCGCTGTCG GCCCATGAAT 
GGCAAAGAAA AGGCTGCATC TTATGACAAG GTGGTAGATG TGGATGTGAA GCTGGGGCAG 
GTGTCTGTGA AGAACCCCAA AGGCACATCC CATGAGATGC CCAAGACCTT CACCTTCGAC 
GCTGTGTATG ATTGGAACGC CAAGCAGTTT GAGCTCTATG ATGAGACGTT CCGACCACTC 
GTGGACTCTG TGCTGCAGGG TTTCAATGGC ACAATTTTTG CCTATGGACA AACAGGAACT 
GGGAAAACCT ATACCATGGA GGGAGTTCGT GGTGACCCTG AAAAAAGAGG GGTCATCCCC 
AACTCCTTTG ATCACATCTT CACCCACATC TCTCGATCTC AGAATCAGCA GTACCTGGTC 
CGGGCGTCTT ACTTAGAGAT CTATCAAGAA GAGATTCGAG ACTTGCTTTC AAAGGATCAG 
ACCAAAAGGC TAGAGCTCAA AGAGAGACCA GATACAGGAG TGTATGTAAA GGATTTGTCT 
TCTTTTGTCA CGAAGAGTGT GAAGGAGATA GAGCATGTGA TGAATGTGGG AAACCAGAAC 
CGGTCTGTCG GTGCTACAAA CATGAATGAG CACAGCTCAC GGTCGCATGC AATCTTTGTT 
ATCACTATTG AATGCAGCGA GGTGGGCCTG GATGGTGAAA ACCACATCCG GGTAGGAAAG 
CTGAATCTTG TAGATCTTGC TGGCAGTGAG CGGCAAGCCA AGACTGGAGC TCAAGGGGAA 
AGACTGAAGG AAGCCACCAA GATCAACCTG TCCCTTTCCG CCTTGGGTAA TGTTATCTCT 
GCCCTTGTAG ATGGCAAAAG CACCCATATT CCATATAGAG ACTCAAAGCT GACCAGGCTT 
CTCCAAGATT CCCTTGGTGG CAATGCCAAA ACTGTGATGG TAGCCAATGT GGGGCCTGCC 
TCTTACAATG TAGAAGAGAC CCTGACCACT CTGAGATATG CCAACCGTGC CAAAAACATT 
AAGAACAAGC CAAGGGTCAA TGAGGACCCA AAGGATGCTC TGCTTCGAGA ATTCCAAGAA 
GAAATTGCTC GGCTCAAGGC CCAGCTGGAA AAACGTTCCA TTGGCAGGAG GAAGAGGCGA 
GAGAAGCGGA GGGAAGGTGG TGGCAGTGGT GGGGGTGGGG AAGAGGAGGA GGAGGAGGGA 
GAAGAGGGTG AGGAGGACGG GGATGATAAG GATGATTACT GGCGGGAACA GCAAGAAAAA 
CTGGAGATTG AGAAGCGGGC CATTGTAGAG GACCACAGCT TGGTTGCAGA GGAGAAGATG 
AGGCTGCTGA AGGAGAAGGA GAAAAAGATG GAGGACCTGC GGCGAGAGAA GGATGCTGCA 
GAGATGCTGG GTGCCAAAAT CAAGGCCATG GAGAGTAAGC TGCTTGTCGG AGGAAAAAAT 
ATAGTAGATC ATACAAACGA ACAGCAGAAG ATCCTGGAGC AAAAACGCCA GGAGATCGCA 
GAGCAGAAAC GTCGAGAAAG AGAAATCCAG CAGCAAATGG AGAGTCGAGA TGAGGAGACC 
CTGGAACTGA AAGAGACTTA CACCTCACTG CAGCAGGAGG TAGACATCAA GACCAAAAAG 
CTCAAAAAGC TCTTTTCCAA GCTTCAGGCC GTGAAGGCCG AGATCCACGA CCTCCAAGAA 
GAACACATCA AAGAGCGCCA GGAGCTGGAG CAGACGCAGA ATGAACTCAC CCGGGAGCTA 
AAGCTCAAGC ATCTTATTAT AGAAAACTTT ATTCCCTTGG AAGAGAAGAA TAAAATTATG 
AATAGATCCT TTTTTGATGA TGAAGAAGAC CATTGGAAAT TACATCCTAT AACCAGACTG 
GAAAACCAGC AGATGATGAA GCGGCCTGTC TCTGCTGTGG GATACAAGAG ACCTCTGAGC 
CAGCATGCAC GGATGTCCAT GATGATTCGG CCAGAGCCCC GGTACAGGGC GGAGAACATC 
ATGCTCTTGG AGTTAGATAT GCCCAGCCGG ACAACCAGAG ACTACGAGGG CCCAGCCATC 
TCTCCCAAGG TTCAGGCTGC GCTGGATGCA GCTCTGCAGG ATGAAGATGA GATACAGGTG 
GATGCCTCAT CCTTTGAAAG TACTGCCAGC AGAAAACCCA AGGCCAGGCC CAAGAGTGGC 
AGGAAATCAG GATCCTCCTC TTCCTCCTCA GGAAACCCTG CATCTCAGTT TTACCCACAG 
TCTCGGGGGC TGGTTCCCAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.
Nature555(7697)463-468(2018 03)
Perez-Garcia V,Fineberg E,Wilson R,Murray A,Mazzeo CI,Tudor C,Sienerth A,White JK,Tuck E,Ryder EJ,Gleeson D,Siragher E,Wardle-Jones H,Staudt N,Wali N,Collins J,Geyer S,Busch-Nentwich EM,Galli A,Smith JC,Robertson E,Adams DJ,Weninger WJ,Mohun T,Hemberger M

Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.
The Journal of biological chemistry291(44)23248-23256(2016 10)
Albracht CD,Guzik-Lendrum S,Rayment I,Gilbert SP

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.
Biophysical journal109(7)1472-82(2015 Oct)
Guzik-Lendrum S,Rank KC,Bensel BM,Taylor KC,Rayment I,Gilbert SP

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Kif3b cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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