Eif3e cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif3e
Entrez Gene ID	16341
Full Name	eukaryotic translation initiation factor 3, subunit E
Synonyms	48kDa,Eif3s6,Int6,eIF3-p46,eIF3-p48
General protein information	Preferred Names eukaryotic translation initiation factor 3, subunit E Names eukaryotic translation initiation factor 3 subunit E MMTV integration site 6 eIF3e eukaryotic translation initiation factor 3, subunit 6 48kDa mammary tumor integration site 6 mammary tumor-associated protein INT-6 viral integration site protein INT-6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 B3.2\|15 16.73 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008388.2	NP_032414.1	eukaryotic translation initiation factor 3 subunit E

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Eif3e	NP_001011990.1
Anopheles gambiae (African malaria mosquito)	EIF3E_ANOGA	XP_308812.2
Mus musculus (house mouse)	Eif3e	NP_032414.1
Oryza sativa (rice)	Os07g0222300	NP_001059202.1
Macaca mulatta (Rhesus monkey)	EIF3E	XP_001090593.1
Bos taurus (cattle)	EIF3E	NP_001029775.1
Drosophila melanogaster (fruit fly)	Int6	NP_477385.1
Arabidopsis thaliana (thale cress)	EIF3E	NP_567047.1
Xenopus tropicalis (tropical clawed frog)	eif3e	NP_989147.1
Schizosaccharomyces pombe (fission yeast)	int6	NP_595367.1
Gallus gallus (chicken)	EIF3E	NP_001006349.1
Danio rerio (zebrafish)	eif3ea	NP_957133.1
Caenorhabditis elegans (roundworm)	eif-3.E	NP_492785.1
Oryza sativa (rice)	Os07g0167000	NP_001058974.2
Oryza sativa (rice)	Os07g0503700	NP_001059730.1
Neurospora crassa	NCU05889	XP_959880.1
Homo sapiens (human)	EIF3E	NP_001559.1
Pan troglodytes (chimpanzee)	EIF3E	XP_003951386.1
Canis lupus familiaris (dog)	EIF3E	XP_532304.2
Magnaporthe oryzae (rice blast fungus)	MGG_03317	XP_003716642.1

Gene Ontology
Bibliography

Related articles in PubMed

Eukaryotic translation initiation factor 3 (eIF3) subunit e is essential for embryonic development and cell proliferation.
Sadato D, Ono T, Gotoh-Saito S, Kajiwara N, Nomura N, Ukaji M, Yang L, Sakimura K, Tajima Y, Oboki K, Shibasaki F
FEBS open bio8(8)1188-1201(2018 Aug)

Silencing of eIF3e promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2α activity.
Hashimoto T, Chen L, Kimura H, Endler A, Koyama H, Miyata T, Shibasaki F, Watanabe T
Journal of vascular surgery64(1)219-226.e3(2016 07)

Expression of truncated eukaryotic initiation factor 3e (eIF3e) resulting from integration of mouse mammary tumor virus (MMTV) causes a shift from cap-dependent to cap-independent translation.
Chiluiza D, Bargo S, Callahan R, Rhoads RE
The Journal of biological chemistry286(36)31288-96(2011 Sep)

Int6/eIF3e silencing promotes functional blood vessel outgrowth and enhances wound healing by upregulating hypoxia-induced factor 2alpha expression.
Chen L, Endler A, Uchida K, Horiguchi S, Morizane Y, Iijima O, Toi M, Shibasaki F
Circulation122(9)910-9(2010 Aug)

Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation.
Tcherkezian J, Brittis PA, Thomas F, Roux PP, Flanagan JG
Cell141(4)632-44(2010 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif3e gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif3e cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu01828	NM_008388.2 Latest version!	Mus musculus eukaryotic translation initiation factor 3, subunit E (Eif3e), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif3e ( NM_008388.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032414.1 Mus musculus eukaryotic translation initiation factor 3, subunit E (Eif3e), mRNA.

Price & Availability↑

CloneID	OMu01828
Clone ID Related Accession (Same CDS sequence)	NM_008388.2
Accession Version	NM_008388.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Mus musculus(house mouse)
Product	eukaryotic translation initiation factor 3 subunit E
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY114098.1, AK161650.1 and AA982184.1. On Jun 27, 2006 this sequence version replaced NM_008388.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC010252.1, AK002576.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGAGT ACGACCTGAC TACTCGCATC GCGCATTTTC TGGATCGGCA CCTGGTCTTT 
CCGCTTCTTG AGTTTCTCTC TGTGAAAGAG ATTTATAATG AAAAAGAATT ATTACAAGGA 
AAATTAGATC TTCTTAGTGA TACCAATATG GTGGATTTTG CTATGGATGT TTACAAAAAC 
CTTTATTCTG ATGATATCCC TCATGCTTTG AGAGAAAAAA GAACCACAGT TGTTGCGCAG 
CTGAAACAGC TCCAGGCAGA AACAGAACCA ATCGTGAAGA TGTTTGAAGA TCCAGAAACT 
ACAAGGCAGA TGCAGTCAAC CAGGGATGGC AGGATGTTAT TTGACTACCT GGCAGACAAA 
CATGGGTTTA GGCAAGAGTA CTTAGATACA CTCTACAGAT ACGCAAAATT CCAGTATGAG 
TGTGGAAATT ACTCTGGAGC TGCAGAGTAT CTTTACTTCT TTAGAGTTTT GGTCCCAGCA 
ACAGATAGAA ATGCTTTAAG TTCGCTCTGG GGAAAACTGG CCTCTGAAAT CTTAATGCAG 
AATTGGGATG CAGCCATGGA AGACCTTACT CGATTAAAAG AAACCATAGA CAATAATTCT 
GTGAGTTCTC CACTCCAGTC TCTTCAGCAG CGAACATGGC TCATTCATTG GTCTCTATTT 
GTTTTTTTCA ACCATCCAAA GGGCCGTGAT AACATTATTG ATCTCTTCCT TTACCAACCA 
CAGTATCTTA ATGCAATTCA GACAATGTGT CCACATATTC TACGCTATTT GACTACTGCC 
GTCATAACCA ACAAAGATGT GCGGAAACGC CGGCAGGTGC TGAAAGATCT GGTGAAAGTG 
ATTCAACAGG AGTCTTACAC ATATAAAGAC CCAATTACAG AATTTGTTGA ATGCCTATAT 
GTTAACTTTG ATTTTGACGG GGCTCAGAAA AAGCTGAGAG AATGTGAATC AGTGCTCGTG 
AATGACTTCT TCCTGGTAGC GTGTCTGGAG GACTTCATTG AGAATGCCCG TCTCTTCATA 
TTTGAGACGT TTTGTCGTAT CCACCAGTGT ATCAGCATTA ATATGTTAGC AGACAAACTG 
AATATGACTC CAGAAGAAGC TGAAAGATGG ATTGTGAATT TGATTAGAAA TGCGAGGTTG 
GATGCCAAGA TTGATTCTAA ACTAGGTCAT GTGGTAATGG GCAACAATGC AGTCTCGCCC 
TACCAGCAAG TGATTGAAAA GACCAAAAGC CTTTCTTTTA GAAGCCAAAT GTTGGCCATG 
AATATCGAAA AGAAACTTAA TCAGAACAGT AGATCAGAGG CTCCCAACTG GGCAACCCAA 
GACTCTGGCT TCTATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032414.1
CDS	45..1382
Translation	MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSDDIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY

Target ORF information:

RefSeq Version	NM_008388.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus eukaryotic translation initiation factor 3, subunit E (Eif3e), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008388.2

ORF Insert Sequence:

ATGGCGGAGT ACGACCTGAC TACTCGCATC GCGCATTTTC TGGATCGGCA CCTGGTCTTT 
CCGCTTCTTG AGTTTCTCTC TGTGAAAGAG ATTTATAATG AAAAAGAATT ATTACAAGGA 
AAATTAGATC TTCTTAGTGA TACCAATATG GTGGATTTTG CTATGGATGT TTACAAAAAC 
CTTTATTCTG ATGATATCCC TCATGCTTTG AGAGAAAAAA GAACCACAGT TGTTGCGCAG 
CTGAAACAGC TCCAGGCAGA AACAGAACCA ATCGTGAAGA TGTTTGAAGA TCCAGAAACT 
ACAAGGCAGA TGCAGTCAAC CAGGGATGGC AGGATGTTAT TTGACTACCT GGCAGACAAA 
CATGGGTTTA GGCAAGAGTA CTTAGATACA CTCTACAGAT ACGCAAAATT CCAGTATGAG 
TGTGGAAATT ACTCTGGAGC TGCAGAGTAT CTTTACTTCT TTAGAGTTTT GGTCCCAGCA 
ACAGATAGAA ATGCTTTAAG TTCGCTCTGG GGAAAACTGG CCTCTGAAAT CTTAATGCAG 
AATTGGGATG CAGCCATGGA AGACCTTACT CGATTAAAAG AAACCATAGA CAATAATTCT 
GTGAGTTCTC CACTCCAGTC TCTTCAGCAG CGAACATGGC TCATTCATTG GTCTCTATTT 
GTTTTTTTCA ACCATCCAAA GGGCCGTGAT AACATTATTG ATCTCTTCCT TTACCAACCA 
CAGTATCTTA ATGCAATTCA GACAATGTGT CCACATATTC TACGCTATTT GACTACTGCC 
GTCATAACCA ACAAAGATGT GCGGAAACGC CGGCAGGTGC TGAAAGATCT GGTGAAAGTG 
ATTCAACAGG AGTCTTACAC ATATAAAGAC CCAATTACAG AATTTGTTGA ATGCCTATAT 
GTTAACTTTG ATTTTGACGG GGCTCAGAAA AAGCTGAGAG AATGTGAATC AGTGCTCGTG 
AATGACTTCT TCCTGGTAGC GTGTCTGGAG GACTTCATTG AGAATGCCCG TCTCTTCATA 
TTTGAGACGT TTTGTCGTAT CCACCAGTGT ATCAGCATTA ATATGTTAGC AGACAAACTG 
AATATGACTC CAGAAGAAGC TGAAAGATGG ATTGTGAATT TGATTAGAAA TGCGAGGTTG 
GATGCCAAGA TTGATTCTAA ACTAGGTCAT GTGGTAATGG GCAACAATGC AGTCTCGCCC 
TACCAGCAAG TGATTGAAAA GACCAAAAGC CTTTCTTTTA GAAGCCAAAT GTTGGCCATG 
AATATCGAAA AGAAACTTAA TCAGAACAGT AGATCAGAGG CTCCCAACTG GGCAACCCAA 
GACTCTGGCT TCTATTAA