Htr2b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Htr2b
Entrez Gene ID	15559
Full Name	5-hydroxytryptamine (serotonin) receptor 2B
Synonyms	5-HT2B,AJ012488,AV377389
General protein information	Preferred Names 5-hydroxytryptamine (serotonin) receptor 2B Names 5-hydroxytryptamine receptor 2B 5-HT-2B 5-HT-2F NP75 protein serotonin receptor 2B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 C5

mRNA and Protein(s)

mRNA	Protein	Name
XM_006529147.2	XP_006529210.1	5-hydroxytryptamine receptor 2B isoform X2
XM_006529146.2	XP_006529209.1	5-hydroxytryptamine receptor 2B isoform X1
XM_006529146.3	XP_006529209.1	5-hydroxytryptamine receptor 2B isoform X1
XM_006529145.2	XP_006529208.1	5-hydroxytryptamine receptor 2B isoform X1
XM_006529145.3	XP_006529208.1	5-hydroxytryptamine receptor 2B isoform X1
NM_008311.3	NP_032337.2	5-hydroxytryptamine receptor 2B
NM_008311.2	NP_032337.2	5-hydroxytryptamine receptor 2B
XM_030250037.1	XP_030105897.1	5-hydroxytryptamine receptor 2B isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	HTR2B	NP_001019804.1
Gallus gallus (chicken)	HTR2B	XP_004943419.1
Homo sapiens (human)	HTR2B	NP_000858.3
Pan troglodytes (chimpanzee)	HTR2B	XP_001144172.1
Bos taurus (cattle)	HTR2B	NP_001192377.1
Mus musculus (house mouse)	Htr2b	NP_032337.2
Rattus norvegicus (Norway rat)	Htr2b	NP_058946.1
Danio rerio (zebrafish)	htr2b	NP_001038208.1
Xenopus tropicalis (tropical clawed frog)	htr2b	XP_004914439.1
Macaca mulatta (Rhesus monkey)	HTR2B	XP_001113095.1

Gene Ontology
Bibliography

Related articles in PubMed

Serotonin signals through a gut-liver axis to regulate hepatic steatosis.
Choi W, Namkung J, Hwang I, Kim H, Lim A, Park HJ, Lee HW, Han KH, Park S, Jeong JS, Bang G, Kim YH, Yadav VK, Karsenty G, Ju YS, Choi C, Suh JM, Park JY, Park S, Kim H
Nature communications9(1)4824(2018 11)

Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice.
Lee SH, Cho PS, Tonello R, Lee HK, Jang JH, Park GY, Hwang SW, Park CK, Jung SJ, Berta T
The Journal of allergy and clinical immunology142(4)1349-1352.e16(2018 10)

Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
Belmer A, Quentin E, Diaz SL, Guiard BP, Fernandez SP, Doly S, Banas SM, Pitychoutis PM, Moutkine I, Muzerelle A, Tchenio A, Roumier A, Mameli M, Maroteaux L
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology43(7)1623-1632(2018 06)

Serotonin 2B Receptors in Mesoaccumbens Dopamine Pathway Regulate Cocaine Responses.
Doly S, Quentin E, Eddine R, Tolu S, Fernandez SP, Bertran-Gonzalez J, Valjent E, Belmer A, Viñals X, Callebert J, Faure P, Meye FJ, Hervé D, Robledo P, Mameli M, Launay JM, Maldonado R, Maroteaux L
The Journal of neuroscience : the official journal of the Society for Neuroscience37(43)10372-10388(2017 10)

Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT
Moutkine I, Quentin E, Guiard BP, Maroteaux L, Doly S
The Journal of biological chemistry292(15)6352-6368(2017 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Htr2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Htr2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu27908	XM_006529146.3 Latest version!	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu27908	XM_006529145.3 Latest version!	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu85026	XM_030250037.1 Latest version!	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu19212	NM_008311.3 Latest version!	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OMu19212	XM_006529147.2 Latest version!	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OMu27908	XM_006529146.2	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu27908	XM_006529145.2	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu19212	NM_008311.2	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Htr2b ( NM_008311.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032337.2 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), mRNA.

Price & Availability↑

CloneID	OMu19212
Clone ID Related Accession (Same CDS sequence)	XM_006529147.2 , NM_008311.3 , NM_008311.2
Accession Version	NM_008311.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1513353600000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK033713.1. On Nov 17, 2006 this sequence version replaced NM_008311.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK033713.1, BC023690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TCGAGACTGA TGTGATTAAT 
CCACACAATG TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTTAT GGTCTTTGGG 
TCACTGGCTG CTTTCTTCGC ACCTCTCACC ATCATGGTAG TCACTTACTT TCTCACCATT 
CACACTTTAC AGAAGAAAGC TTACTTGGTC AAAAATAAGC CACCTCAACG CCTAACACGG 
TGGACTGTGC CCACAGTTTT CCTAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGGTG 
GCAATGCTGG ATGGGTCTCA CAGGGATAAA ATTCTACCTA ACTCAAGTGA TGAGACACTT 
ATGCGAAGAA TGTCCTCAGT TGGAAAAAGA TCAGCCCAAA CCATTTCTAA TGAGCAGAGA 
GCCTCGAAGG CCCTTGGAGT CGTGTTTTTC CTTTTTCTGC TTATGTGGTG CCCCTTTTTT 
ATTACAAATC TAACTTTAGC TCTGTGTGAT TCCTGCAATC AGACCACTCT CAAAACACTC 
CTGGAGATAT TTGTGTGGAT AGGCTACGTT TCCTCGGGGG TGAATCCTCT GATCTATACA 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCGAGCC 
ACAAAGTCAG TAAAAGCACT TAGGAAGTTT TCCAGTACAC TTTGTTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAATGAGGCT CCGAAGTTCA ACCATTCAGT CCTCATCAAT CATCCTCCTC 
GATACCCTTC TCACTGAAAA CGATGGCGAC AAAGCGGAAG AGCAGGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032337.2
CDS	328..1767
Translation	MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	NM_008311.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008311.2

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TCGAGACTGA TGTGATTAAT 
CCACACAATG TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTTAT GGTCTTTGGG 
TCACTGGCTG CTTTCTTCGC ACCTCTCACC ATCATGGTAG TCACTTACTT TCTCACCATT 
CACACTTTAC AGAAGAAAGC TTACTTGGTC AAAAATAAGC CACCTCAACG CCTAACACGG 
TGGACTGTGC CCACAGTTTT CCTAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGGTG 
GCAATGCTGG ATGGGTCTCA CAGGGATAAA ATTCTACCTA ACTCAAGTGA TGAGACACTT 
ATGCGAAGAA TGTCCTCAGT TGGAAAAAGA TCAGCCCAAA CCATTTCTAA TGAGCAGAGA 
GCCTCGAAGG CCCTTGGAGT CGTGTTTTTC CTTTTTCTGC TTATGTGGTG CCCCTTTTTT 
ATTACAAATC TAACTTTAGC TCTGTGTGAT TCCTGCAATC AGACCACTCT CAAAACACTC 
CTGGAGATAT TTGTGTGGAT AGGCTACGTT TCCTCGGGGG TGAATCCTCT GATCTATACA 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCGAGCC 
ACAAAGTCAG TAAAAGCACT TAGGAAGTTT TCCAGTACAC TTTGTTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAATGAGGCT CCGAAGTTCA ACCATTCAGT CCTCATCAAT CATCCTCCTC 
GATACCCTTC TCACTGAAAA CGATGGCGAC AAAGCGGAAG AGCAGGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( XM_006529146.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529209.1 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu27908
Clone ID Related Accession (Same CDS sequence)	XM_006529146.2 , XM_006529146.3 , XM_006529145.2 , XM_006529145.3
Accession Version	XM_006529146.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1488bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006529146.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529209.1
CDS	2019..3506
Translation	MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGMWGMPLFPYGQNASSGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	XM_006529146.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529146.2

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( XM_006529146.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529209.1 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27908
Clone ID Related Accession (Same CDS sequence)	XM_006529146.2 , XM_006529146.3 , XM_006529145.2 , XM_006529145.3
Accession Version	XM_006529146.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1488bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529146.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529209.1
CDS	388..1875
Translation	MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGMWGMPLFPYGQNASSGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	XM_006529146.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529146.3

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( XM_006529145.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529208.1 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27908
Clone ID Related Accession (Same CDS sequence)	XM_006529146.2 , XM_006529146.3 , XM_006529145.2 , XM_006529145.3
Accession Version	XM_006529145.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1488bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006529145.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529208.1
CDS	2781..4268
Translation	MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGMWGMPLFPYGQNASSGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	XM_006529145.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529145.2

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( XM_006529145.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529208.1 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu27908
Clone ID Related Accession (Same CDS sequence)	XM_006529146.2 , XM_006529146.3 , XM_006529145.2 , XM_006529145.3
Accession Version	XM_006529145.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1488bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529145.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529208.1
CDS	5350..6837
Translation	MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGMWGMPLFPYGQNASSGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	XM_006529145.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529145.3

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GTATGTGGGG AATGCCTCTA TTTCCATATG GCCAGAATGC CAGCTCTGGC 
ATCGCCATCC CAGTCCCTAT TAAAGGAATC GAGACTGATG TGATTAATCC ACACAATGTC 
ACCTGTGAGC TGACAAAGGA CCGCTTTGGC AGTTTTATGG TCTTTGGGTC ACTGGCTGCT 
TTCTTCGCAC CTCTCACCAT CATGGTAGTC ACTTACTTTC TCACCATTCA CACTTTACAG 
AAGAAAGCTT ACTTGGTCAA AAATAAGCCA CCTCAACGCC TAACACGGTG GACTGTGCCC 
ACAGTTTTCC TAAGGGAAGA CTCATCCTTT TCATCACCAG AAAAGGTGGC AATGCTGGAT 
GGGTCTCACA GGGATAAAAT TCTACCTAAC TCAAGTGATG AGACACTTAT GCGAAGAATG 
TCCTCAGTTG GAAAAAGATC AGCCCAAACC ATTTCTAATG AGCAGAGAGC CTCGAAGGCC 
CTTGGAGTCG TGTTTTTCCT TTTTCTGCTT ATGTGGTGCC CCTTTTTTAT TACAAATCTA 
ACTTTAGCTC TGTGTGATTC CTGCAATCAG ACCACTCTCA AAACACTCCT GGAGATATTT 
GTGTGGATAG GCTACGTTTC CTCGGGGGTG AATCCTCTGA TCTATACACT CTTCAATAAG 
ACATTTCGGG AAGCATTTGG CAGGTACATC ACCTGCAATT ACCGAGCCAC AAAGTCAGTA 
AAAGCACTTA GGAAGTTTTC CAGTACACTT TGTTTTGGGA ATTCAATGGT AGAAAACTCT 
AAATTTTTCA CAAAACATGG AATTCGAAAT GGGATCAACC CTGCCATGTA CCAGAGCCCA 
ATGAGGCTCC GAAGTTCAAC CATTCAGTCC TCATCAATCA TCCTCCTCGA TACCCTTCTC 
ACTGAAAACG ATGGCGACAA AGCGGAAGAG CAGGTCAGCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( XM_030250037.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030105897.1 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu85026
Clone ID Related Accession (Same CDS sequence)	XM_030250037.1
Accession Version	XM_030250037.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCCTC CCACTGGCCC TGTGTCCTGC CTGGTTATTC CTCGATGTTC TCTTTTCAAC 
TGCCTCCATC ATGCATCTCT GTGCCATTTC CCTGGACCGC TATATAGCCA TCAAAAAGCC 
AATTCAGGCC AATCAGTGCA ACTCCCGGGC TACTGCATTC ATCAAGATTA CAGTGGCATC 
GCCATCCCAG TCCCTATTAA AGGAATCGAG ACTGATGTGA TTAATCCACA CAATGTCACC 
TGTGAGCTGA CAAAGGACCG CTTTGGCAGT TTTATGGTCT TTGGGTCACT GGCTGCTTTC 
TTCGCACCTC TCACCATCAT GGTAGTCACT TACTTTCTCA CCATTCACAC TTTACAGAAG 
AAAGCTTACT TGGTCAAAAA TAAGCCACCT CAACGCCTAA CACGGTGGAC TGTGCCCACA 
GTTTTCCTAA GGGAAGACTC ATCCTTTTCA TCACCAGAAA AGGTGGCAAT GCTGGATGGG 
TCTCACAGGG ATAAAATTCT ACCTAACTCA AGTGATGAGA CACTTATGCG AAGAATGTCC 
TCAGTTGGAA AAAGATCAGC CCAAACCATT TCTAATGAGC AGAGAGCCTC GAAGGCCCTT 
GGAGTCGTGT TTTTCCTTTT TCTGCTTATG TGGTGCCCCT TTTTTATTAC AAATCTAACT 
TTAGCTCTGT GTGATTCCTG CAATCAGACC ACTCTCAAAA CACTCCTGGA GATATTTGTG 
TGGATAGGCT ACGTTTCCTC GGGGGTGAAT CCTCTGATCT ATACACTCTT CAATAAGACA 
TTTCGGGAAG CATTTGGCAG GTACATCACC TGCAATTACC GAGCCACAAA GTCAGTAAAA 
GCACTTAGGA AGTTTTCCAG TACACTTTGT TTTGGGAATT CAATGGTAGA AAACTCTAAA 
TTTTTCACAA AACATGGAAT TCGAAATGGG ATCAACCCTG CCATGTACCA GAGCCCAATG 
AGGCTCCGAA GTTCAACCAT TCAGTCCTCA TCAATCATCC TCCTCGATAC CCTTCTCACT 
GAAAACGATG GCGACAAAGC GGAAGAGCAG GTCAGCTACA TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030105897.1
CDS	147..1211
Translation	MAPPTGPVSCLVIPRCSLFNCLHHASLCHFPGPLYSHQKANSGQSVQLPGYCIHQDYSGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	XM_030250037.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250037.1

ORF Insert Sequence:

ATGGCCCCTC CCACTGGCCC TGTGTCCTGC CTGGTTATTC CTCGATGTTC TCTTTTCAAC 
TGCCTCCATC ATGCATCTCT GTGCCATTTC CCTGGACCGC TATATAGCCA TCAAAAAGCC 
AATTCAGGCC AATCAGTGCA ACTCCCGGGC TACTGCATTC ATCAAGATTA CAGTGGCATC 
GCCATCCCAG TCCCTATTAA AGGAATCGAG ACTGATGTGA TTAATCCACA CAATGTCACC 
TGTGAGCTGA CAAAGGACCG CTTTGGCAGT TTTATGGTCT TTGGGTCACT GGCTGCTTTC 
TTCGCACCTC TCACCATCAT GGTAGTCACT TACTTTCTCA CCATTCACAC TTTACAGAAG 
AAAGCTTACT TGGTCAAAAA TAAGCCACCT CAACGCCTAA CACGGTGGAC TGTGCCCACA 
GTTTTCCTAA GGGAAGACTC ATCCTTTTCA TCACCAGAAA AGGTGGCAAT GCTGGATGGG 
TCTCACAGGG ATAAAATTCT ACCTAACTCA AGTGATGAGA CACTTATGCG AAGAATGTCC 
TCAGTTGGAA AAAGATCAGC CCAAACCATT TCTAATGAGC AGAGAGCCTC GAAGGCCCTT 
GGAGTCGTGT TTTTCCTTTT TCTGCTTATG TGGTGCCCCT TTTTTATTAC AAATCTAACT 
TTAGCTCTGT GTGATTCCTG CAATCAGACC ACTCTCAAAA CACTCCTGGA GATATTTGTG 
TGGATAGGCT ACGTTTCCTC GGGGGTGAAT CCTCTGATCT ATACACTCTT CAATAAGACA 
TTTCGGGAAG CATTTGGCAG GTACATCACC TGCAATTACC GAGCCACAAA GTCAGTAAAA 
GCACTTAGGA AGTTTTCCAG TACACTTTGT TTTGGGAATT CAATGGTAGA AAACTCTAAA 
TTTTTCACAA AACATGGAAT TCGAAATGGG ATCAACCCTG CCATGTACCA GAGCCCAATG 
AGGCTCCGAA GTTCAACCAT TCAGTCCTCA TCAATCATCC TCCTCGATAC CCTTCTCACT 
GAAAACGATG GCGACAAAGC GGAAGAGCAG GTCAGCTACA TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( NM_008311.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032337.2 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), mRNA.

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CloneID	OMu19212
Clone ID Related Accession (Same CDS sequence)	XM_006529147.2 , NM_008311.3 , NM_008311.2
Accession Version	NM_008311.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569340800000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC157768.4. On Aug 21, 2018 this sequence version replaced NM_008311.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK033713.1, BC023690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TCGAGACTGA TGTGATTAAT 
CCACACAATG TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTTAT GGTCTTTGGG 
TCACTGGCTG CTTTCTTCGC ACCTCTCACC ATCATGGTAG TCACTTACTT TCTCACCATT 
CACACTTTAC AGAAGAAAGC TTACTTGGTC AAAAATAAGC CACCTCAACG CCTAACACGG 
TGGACTGTGC CCACAGTTTT CCTAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGGTG 
GCAATGCTGG ATGGGTCTCA CAGGGATAAA ATTCTACCTA ACTCAAGTGA TGAGACACTT 
ATGCGAAGAA TGTCCTCAGT TGGAAAAAGA TCAGCCCAAA CCATTTCTAA TGAGCAGAGA 
GCCTCGAAGG CCCTTGGAGT CGTGTTTTTC CTTTTTCTGC TTATGTGGTG CCCCTTTTTT 
ATTACAAATC TAACTTTAGC TCTGTGTGAT TCCTGCAATC AGACCACTCT CAAAACACTC 
CTGGAGATAT TTGTGTGGAT AGGCTACGTT TCCTCGGGGG TGAATCCTCT GATCTATACA 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCGAGCC 
ACAAAGTCAG TAAAAGCACT TAGGAAGTTT TCCAGTACAC TTTGTTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAATGAGGCT CCGAAGTTCA ACCATTCAGT CCTCATCAAT CATCCTCCTC 
GATACCCTTC TCACTGAAAA CGATGGCGAC AAAGCGGAAG AGCAGGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032337.2
CDS	337..1776
Translation	MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	NM_008311.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008311.3

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TCGAGACTGA TGTGATTAAT 
CCACACAATG TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTTAT GGTCTTTGGG 
TCACTGGCTG CTTTCTTCGC ACCTCTCACC ATCATGGTAG TCACTTACTT TCTCACCATT 
CACACTTTAC AGAAGAAAGC TTACTTGGTC AAAAATAAGC CACCTCAACG CCTAACACGG 
TGGACTGTGC CCACAGTTTT CCTAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGGTG 
GCAATGCTGG ATGGGTCTCA CAGGGATAAA ATTCTACCTA ACTCAAGTGA TGAGACACTT 
ATGCGAAGAA TGTCCTCAGT TGGAAAAAGA TCAGCCCAAA CCATTTCTAA TGAGCAGAGA 
GCCTCGAAGG CCCTTGGAGT CGTGTTTTTC CTTTTTCTGC TTATGTGGTG CCCCTTTTTT 
ATTACAAATC TAACTTTAGC TCTGTGTGAT TCCTGCAATC AGACCACTCT CAAAACACTC 
CTGGAGATAT TTGTGTGGAT AGGCTACGTT TCCTCGGGGG TGAATCCTCT GATCTATACA 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCGAGCC 
ACAAAGTCAG TAAAAGCACT TAGGAAGTTT TCCAGTACAC TTTGTTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAATGAGGCT CCGAAGTTCA ACCATTCAGT CCTCATCAAT CATCCTCCTC 
GATACCCTTC TCACTGAAAA CGATGGCGAC AAAGCGGAAG AGCAGGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Htr2b ( XM_006529147.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529210.1 Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X3, mRNA.

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CloneID	OMu19212
Clone ID Related Accession (Same CDS sequence)	XM_006529147.2 , NM_008311.3 , NM_008311.2
Accession Version	XM_006529147.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 2B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006529147.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TCGAGACTGA TGTGATTAAT 
CCACACAATG TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTTAT GGTCTTTGGG 
TCACTGGCTG CTTTCTTCGC ACCTCTCACC ATCATGGTAG TCACTTACTT TCTCACCATT 
CACACTTTAC AGAAGAAAGC TTACTTGGTC AAAAATAAGC CACCTCAACG CCTAACACGG 
TGGACTGTGC CCACAGTTTT CCTAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGGTG 
GCAATGCTGG ATGGGTCTCA CAGGGATAAA ATTCTACCTA ACTCAAGTGA TGAGACACTT 
ATGCGAAGAA TGTCCTCAGT TGGAAAAAGA TCAGCCCAAA CCATTTCTAA TGAGCAGAGA 
GCCTCGAAGG CCCTTGGAGT CGTGTTTTTC CTTTTTCTGC TTATGTGGTG CCCCTTTTTT 
ATTACAAATC TAACTTTAGC TCTGTGTGAT TCCTGCAATC AGACCACTCT CAAAACACTC 
CTGGAGATAT TTGTGTGGAT AGGCTACGTT TCCTCGGGGG TGAATCCTCT GATCTATACA 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCGAGCC 
ACAAAGTCAG TAAAAGCACT TAGGAAGTTT TCCAGTACAC TTTGTTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAATGAGGCT CCGAAGTTCA ACCATTCAGT CCTCATCAAT CATCCTCCTC 
GATACCCTTC TCACTGAAAA CGATGGCGAC AAAGCGGAAG AGCAGGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529210.1
CDS	2781..4220
Translation	MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI

Target ORF information:

RefSeq Version	XM_006529147.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529147.2

ORF Insert Sequence:

ATGGCTTCAT CTTATAAAAT GTCTGAACAA AGCACAACTT CTGAGCACAT TTTACAGAAG 
ACATGTGATC ACCTGATCCT GACTAACCGT TCTGGATTAG AGACAGACTC AGTAGCAGAG 
GAAATGAAGC AGACTGTGGA GGGACAGGGG CATACAGTGC ACTGGGCAGC TCTCCTGATA 
CTCGCGGTGA TAATACCCAC CATTGGTGGG AACATCCTTG TGATTCTGGC TGTTGCACTG 
GAGAAAAGGC TGCAGTACGC TACCAACTAC TTTTTAATGT CCTTGGCGAT AGCAGATTTG 
CTGGTTGGAT TGTTTGTGAT GCCGATTGCC CTCTTGACAA TCATGTTTGA GGCTATATGG 
CCCCTCCCAC TGGCCCTGTG TCCTGCCTGG TTATTCCTCG ATGTTCTCTT TTCAACTGCC 
TCCATCATGC ATCTCTGTGC CATTTCCCTG GACCGCTATA TAGCCATCAA AAAGCCAATT 
CAGGCCAATC AGTGCAACTC CCGGGCTACT GCATTCATCA AGATTACAGT GGTATGGTTA 
ATTTCAATAG GCATCGCCAT CCCAGTCCCT ATTAAAGGAA TCGAGACTGA TGTGATTAAT 
CCACACAATG TCACCTGTGA GCTGACAAAG GACCGCTTTG GCAGTTTTAT GGTCTTTGGG 
TCACTGGCTG CTTTCTTCGC ACCTCTCACC ATCATGGTAG TCACTTACTT TCTCACCATT 
CACACTTTAC AGAAGAAAGC TTACTTGGTC AAAAATAAGC CACCTCAACG CCTAACACGG 
TGGACTGTGC CCACAGTTTT CCTAAGGGAA GACTCATCCT TTTCATCACC AGAAAAGGTG 
GCAATGCTGG ATGGGTCTCA CAGGGATAAA ATTCTACCTA ACTCAAGTGA TGAGACACTT 
ATGCGAAGAA TGTCCTCAGT TGGAAAAAGA TCAGCCCAAA CCATTTCTAA TGAGCAGAGA 
GCCTCGAAGG CCCTTGGAGT CGTGTTTTTC CTTTTTCTGC TTATGTGGTG CCCCTTTTTT 
ATTACAAATC TAACTTTAGC TCTGTGTGAT TCCTGCAATC AGACCACTCT CAAAACACTC 
CTGGAGATAT TTGTGTGGAT AGGCTACGTT TCCTCGGGGG TGAATCCTCT GATCTATACA 
CTCTTCAATA AGACATTTCG GGAAGCATTT GGCAGGTACA TCACCTGCAA TTACCGAGCC 
ACAAAGTCAG TAAAAGCACT TAGGAAGTTT TCCAGTACAC TTTGTTTTGG GAATTCAATG 
GTAGAAAACT CTAAATTTTT CACAAAACAT GGAATTCGAA ATGGGATCAA CCCTGCCATG 
TACCAGAGCC CAATGAGGCT CCGAAGTTCA ACCATTCAGT CCTCATCAAT CATCCTCCTC 
GATACCCTTC TCACTGAAAA CGATGGCGAC AAAGCGGAAG AGCAGGTCAG CTACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Serotonin signals through a gut-liver axis to regulate hepatic steatosis.
Nature communications9(1)4824(2018 11)
Choi W,Namkung J,Hwang I,Kim H,Lim A,Park HJ,Lee HW,Han KH,Park S,Jeong JS,Bang G,Kim YH,Yadav VK,Karsenty G,Ju YS,Choi C,Suh JM,Park JY,Park S,Kim H

Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice.
The Journal of allergy and clinical immunology142(4)1349-1352.e16(2018 10)
Lee SH,Cho PS,Tonello R,Lee HK,Jang JH,Park GY,Hwang SW,Park CK,Jung SJ,Berta T

Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology43(7)1623-1632(2018 06)
Belmer A,Quentin E,Diaz SL,Guiard BP,Fernandez SP,Doly S,Banas SM,Pitychoutis PM,Moutkine I,Muzerelle A,Tchenio A,Roumier A,Mameli M,Maroteaux L

Serotonin 2B Receptors in Mesoaccumbens Dopamine Pathway Regulate Cocaine Responses.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(43)10372-10388(2017 10)
Doly S,Quentin E,Eddine R,Tolu S,Fernandez SP,Bertran-Gonzalez J,Valjent E,Belmer A,Viñals X,Callebert J,Faure P,Meye FJ,Hervé D,Robledo P,Mameli M,Launay JM,Maldonado R,Maroteaux L

Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT
The Journal of biological chemistry292(15)6352-6368(2017 04)
Moutkine I,Quentin E,Guiard BP,Maroteaux L,Doly S

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Htr2b cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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