Hsp90aa1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hsp90aa1
Entrez Gene ID	15519
Full Name	heat shock protein 90, alpha (cytosolic), class A member 1
Synonyms	86kDa,89kDa,AL024080,AL024147,Hsp86-1,Hsp89,Hsp90,Hspca,hsp4
General protein information	Preferred Names heat shock protein 90, alpha (cytosolic), class A member 1 Names heat shock protein HSP 90-alpha HSP 86 HSP86 TSTA heat shock 86 kDa heat shock protein 1, alpha heat shock protein 90kDa alpha (cytosolic), class A member 1 heat shock protein, 1 heat shock protein, 86 kDa 1 heat shock protein, 89 kDa tumor-specific transplantation 86 kDa antigen
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12 F1\|12 60.75 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010480.5	NP_034610.1	heat shock protein HSP 90-alpha

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os09g0482100	NP_001063500.1
Canis lupus familiaris (dog)	HSP90AA1	XP_005623992.1
Arabidopsis thaliana (thale cress)	HSP81-3	NP_200412.1
Arabidopsis thaliana (thale cress)	HSP81-2	NP_200414.1
Oryza sativa (rice)	Os09g0482400	NP_001063503.1
Macaca mulatta (Rhesus monkey)	HSP90AA1	XP_002805263.1
Arabidopsis thaliana (thale cress)	Hsp81.4	NP_200411.1
Pan troglodytes (chimpanzee)	HSP90AA1	NP_001092042.1
Mus musculus (house mouse)	Hsp90aa1	NP_034610.1
Rattus norvegicus (Norway rat)	Hsp90aa1	NP_786937.1
Oryza sativa (rice)	Os09g0482610	NP_001175894.1
Bos taurus (cattle)	HSP90AA1	NP_001012688.1
Gallus gallus (chicken)	HSP90AA1	NP_001103255.1
Homo sapiens (human)	HSP90AA1	NP_001017963.2
Danio rerio (zebrafish)	hsp90aa1.2	NP_001038538.1
Danio rerio (zebrafish)	hsp90aa1.1	NP_571403.1
Xenopus tropicalis (tropical clawed frog)	hsp90aa1.1	NP_001016282.1

Gene Ontology
Bibliography

Related articles in PubMed

Reduction of cardiac TGFβ-mediated profibrotic events by inhibition of Hsp90 with engineered protein.
Cáceres RA, Chavez T, Maestro D, Palanca AR, Bolado P, Madrazo F, Aires A, Cortajarena AL, Villar AV
Journal of molecular and cellular cardiology12375-87(2018 10)

ZMYND10 functions in a chaperone relay during axonemal dynein assembly.
Mali GR, Yeyati PL, Mizuno S, Dodd DO, Tennant PA, Keighren MA, Zur Lage P, Shoemark A, Garcia-Munoz A, Shimada A, Takeda H, Edlich F, Takahashi S, von Kreigsheim A, Jarman AP, Mill P
eLife7(2018 06)

A switch point in the molecular chaperone Hsp90 responding to client interaction.
Rutz DA, Luo Q, Freiburger L, Madl T, Kaila VRI, Sattler M, Buchner J
Nature communications9(1)1472(2018 04)

Periconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaptation to pregnancy.
Brown HM, Green ES, Tan TCY, Gonzalez MB, Rumbold AR, Hull ML, Norman RJ, Packer NH, Robertson SA, Thompson JG
Scientific reports8(1)2114(2018 02)

Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Woodford MR, Sager RA, Marris E, Dunn DM, Blanden AR, Murphy RL, Rensing N, Shapiro O, Panaretou B, Prodromou C, Loh SN, Gutmann DH, Bourboulia D, Bratslavsky G, Wong M, Mollapour M
The EMBO journal36(24)3650-3665(2017 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hsp90aa1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hsp90aa1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15872	NM_010480.5 Latest version!	Mus musculus heat shock protein 90, alpha (cytosolic), class A member 1 (Hsp90aa1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$433.30 $619.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hsp90aa1 ( NM_010480.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034610.1 Mus musculus heat shock protein 90, alpha (cytosolic), class A member 1 (Hsp90aa1), mRNA.

Price & Availability↑

CloneID	OMu15872
Clone ID Related Accession (Same CDS sequence)	NM_010480.5
Accession Version	NM_010480.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2202bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	heat shock protein HSP 90-alpha
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL596265.12 and AC152827.4. On Apr 28, 2007 this sequence version replaced NM_010480.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK004658.1, SRR1660811.159643.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGCCTGAGG AAACCCAGAC CCAAGACCAA CCAATGGAGG AGGAGGAGGT CGAGACCTTT 
GCCTTTCAGG CAGAAATTGC CCAGTTAATG TCCTTGATCA TCAATACCTT CTACTCGAAC 
AAAGAGATCT TTCTGAGGGA GCTCATCTCC AATTCATCGG ACGCTCTGGA TAAAATCCGT 
TACGAGAGCC TGACGGACCC CAGTAAACTG GACTCGGGGA AGGAGCTGCA CATCAATCTC 
ATTCCCAGCA AACAGGACCG AACCCTGACC ATTGTGGATA CCGGGATTGG AATGACCAAG 
GCCGACTTGA TCAATAACCT TGGCACCATT GCCAAGTCGG GCACCAAAGC CTTCATGGAG 
GCTTTGCAGG CTGGTGCAGA TATCTCTATG ATTGGCCAGT TTGGTGTTGG TTTTTACTCT 
GCCTATTTGG TTGCTGAGAA AGTGACTGTC ATCACGAAGC ATAACGACGA TGAGCAGTAT 
GCCTGGGAGT CCTCAGCTGG GGGATCCTTC ACAGTGAGGA CTGACACAGG TGAACCAATG 
GGTCGTGGAA CAAAGGTTAT CTTGCATCTG AAAGAAGACC AAACAGAGTA TTTGGAGGAA 
AGGAGAATAA AGGAGATCGT GAAGAAGCAT TCTCAGTTCA TTGGCTATCC CATTACTCTC 
TTTGTGGAGA AGGAACGAGA TAAGGAAGTC AGTGATGATG AGGCTGAAGA AAAGGAAGAG 
AAAGAGGAAG AGAAAGAAAA AGAAGAAAAG GAGTCTGATG ATAAACCTGA AATAGAAGAT 
GTTGGCTCTG ATGAAGAAGA GGAGGAGAAG AAGGATGGTG ACAAGAAGAA AAAGAAGAAG 
ATAAAGGAAA AGTACATTGA TCAAGAAGAA CTCAACAAAA CAAAGCCGAT TTGGACGAGA 
AATCCTGATG ACATCACTAA TGAGGAATAT GGAGAGTTCT ACAAGAGCTT AACTAACGAT 
TGGGAAGAAC ACTTGGCAGT AAAGCATTTT TCTGTTGAAG GACAATTAGA ATTCCGGGCC 
CTTCTTTTTG TCCCAAGACG CGCTCCTTTT GATCTGTTTG AAAACAGAAA GAAAAAGAAC 
AACATCAAGT TGTATGTTCG CAGAGTTTTT ATCATGGATA ACTGTGAGGA ATTAATCCCT 
GAGTATCTGA ATTTCATTAG AGGGGTAGTG GATTCTGAGG ATCTCCCTCT AAATATTTCC 
CGTGAAATGC TGCAACAAAG TAAAATTCTG AAAGTTATCA GAAAGAATTT GGTCAAGAAA 
TGCTTAGAAC TATTTACTGA ACTAGCAGAA GATAAAGAGA ACTACAAAAA GTTTTATGAG 
CAGTTCTCAA AAAATATAAA GCTTGGAATT CACGAGGACT CTCAGAATCG GAAGAAGCTT 
TCAGAGCTGT TGCGGTACTA CACATCTGCT TCTGGGGACG AGATGGTTTC TCTGAAGGAC 
TACTGTACCA GAATGAAGGA AAACCAGAAG CACATCTATT TTATCACAGG TGAGACCAAG 
GACCAGGTTG CTAACTCCGC CTTTGTGGAA CGTCTCCGAA AGCATGGCTT AGAAGTAATT 
TATATGATTG AGCCCATTGA TGAGTATTGT GTGCAACAGC TGAAGGAATT TGAGGGCAAG 
ACCTTGGTGT CTGTTACCAA AGAAGGACTG GAACTTCCAG AAGATGAAGA GGAAAAGAAG 
AAACAGGAAG AGAAAAAGAC AAAATTTGAG AACCTCTGCA AAATTATGAA AGATATTTTG 
GAGAAGAAGG TTGAAAAGGT GGTTGTGTCA AACCGACTGG TGACATCCCC GTGCTGTATT 
GTCACAAGCA CATATGGGTG GACAGCAAAC ATGGAGAGAA TCATGAAAGC TCAAGCCCTC 
AGAGACAACT CAACAATGGG TTACATGGCA GCAAAGAAAC ACCTGGAGAT AAATCCTGAT 
CACTCCATTA TTGAAACCTT AAGGCAAAAG GCAGAGGCTG ACAAGAATGA CAAATCTGTG 
AAGGATCTGG TCATCTTGCT GTATGAAACT GCACTCCTAT CTTCTGGCTT CAGTCTGGAA 
GATCCCCAGA CCCATGCTAA CAGGATCTAC AGGATGATCA AGCTTGGTCT AGGTATTGAT 
GAGGATGATC CTACTGTGGA TGACACCAGT GCTGCTGTAA CTGAAGAAAT GCCTCCCCTG 
GAAGGAGATG ACGACACATC ACGCATGGAA GAAGTAGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034610.1
CDS	145..2346
Translation	MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMPPLEGDDDTSRMEEVD

Target ORF information:

RefSeq Version	NM_010480.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus heat shock protein 90, alpha (cytosolic), class A member 1 (Hsp90aa1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010480.5

ORF Insert Sequence:

ATGCCTGAGG AAACCCAGAC CCAAGACCAA CCAATGGAGG AGGAGGAGGT CGAGACCTTT 
GCCTTTCAGG CAGAAATTGC CCAGTTAATG TCCTTGATCA TCAATACCTT CTACTCGAAC 
AAAGAGATCT TTCTGAGGGA GCTCATCTCC AATTCATCGG ACGCTCTGGA TAAAATCCGT 
TACGAGAGCC TGACGGACCC CAGTAAACTG GACTCGGGGA AGGAGCTGCA CATCAATCTC 
ATTCCCAGCA AACAGGACCG AACCCTGACC ATTGTGGATA CCGGGATTGG AATGACCAAG 
GCCGACTTGA TCAATAACCT TGGCACCATT GCCAAGTCGG GCACCAAAGC CTTCATGGAG 
GCTTTGCAGG CTGGTGCAGA TATCTCTATG ATTGGCCAGT TTGGTGTTGG TTTTTACTCT 
GCCTATTTGG TTGCTGAGAA AGTGACTGTC ATCACGAAGC ATAACGACGA TGAGCAGTAT 
GCCTGGGAGT CCTCAGCTGG GGGATCCTTC ACAGTGAGGA CTGACACAGG TGAACCAATG 
GGTCGTGGAA CAAAGGTTAT CTTGCATCTG AAAGAAGACC AAACAGAGTA TTTGGAGGAA 
AGGAGAATAA AGGAGATCGT GAAGAAGCAT TCTCAGTTCA TTGGCTATCC CATTACTCTC 
TTTGTGGAGA AGGAACGAGA TAAGGAAGTC AGTGATGATG AGGCTGAAGA AAAGGAAGAG 
AAAGAGGAAG AGAAAGAAAA AGAAGAAAAG GAGTCTGATG ATAAACCTGA AATAGAAGAT 
GTTGGCTCTG ATGAAGAAGA GGAGGAGAAG AAGGATGGTG ACAAGAAGAA AAAGAAGAAG 
ATAAAGGAAA AGTACATTGA TCAAGAAGAA CTCAACAAAA CAAAGCCGAT TTGGACGAGA 
AATCCTGATG ACATCACTAA TGAGGAATAT GGAGAGTTCT ACAAGAGCTT AACTAACGAT 
TGGGAAGAAC ACTTGGCAGT AAAGCATTTT TCTGTTGAAG GACAATTAGA ATTCCGGGCC 
CTTCTTTTTG TCCCAAGACG CGCTCCTTTT GATCTGTTTG AAAACAGAAA GAAAAAGAAC 
AACATCAAGT TGTATGTTCG CAGAGTTTTT ATCATGGATA ACTGTGAGGA ATTAATCCCT 
GAGTATCTGA ATTTCATTAG AGGGGTAGTG GATTCTGAGG ATCTCCCTCT AAATATTTCC 
CGTGAAATGC TGCAACAAAG TAAAATTCTG AAAGTTATCA GAAAGAATTT GGTCAAGAAA 
TGCTTAGAAC TATTTACTGA ACTAGCAGAA GATAAAGAGA ACTACAAAAA GTTTTATGAG 
CAGTTCTCAA AAAATATAAA GCTTGGAATT CACGAGGACT CTCAGAATCG GAAGAAGCTT 
TCAGAGCTGT TGCGGTACTA CACATCTGCT TCTGGGGACG AGATGGTTTC TCTGAAGGAC 
TACTGTACCA GAATGAAGGA AAACCAGAAG CACATCTATT TTATCACAGG TGAGACCAAG 
GACCAGGTTG CTAACTCCGC CTTTGTGGAA CGTCTCCGAA AGCATGGCTT AGAAGTAATT 
TATATGATTG AGCCCATTGA TGAGTATTGT GTGCAACAGC TGAAGGAATT TGAGGGCAAG 
ACCTTGGTGT CTGTTACCAA AGAAGGACTG GAACTTCCAG AAGATGAAGA GGAAAAGAAG 
AAACAGGAAG AGAAAAAGAC AAAATTTGAG AACCTCTGCA AAATTATGAA AGATATTTTG 
GAGAAGAAGG TTGAAAAGGT GGTTGTGTCA AACCGACTGG TGACATCCCC GTGCTGTATT 
GTCACAAGCA CATATGGGTG GACAGCAAAC ATGGAGAGAA TCATGAAAGC TCAAGCCCTC 
AGAGACAACT CAACAATGGG TTACATGGCA GCAAAGAAAC ACCTGGAGAT AAATCCTGAT 
CACTCCATTA TTGAAACCTT AAGGCAAAAG GCAGAGGCTG ACAAGAATGA CAAATCTGTG 
AAGGATCTGG TCATCTTGCT GTATGAAACT GCACTCCTAT CTTCTGGCTT CAGTCTGGAA 
GATCCCCAGA CCCATGCTAA CAGGATCTAC AGGATGATCA AGCTTGGTCT AGGTATTGAT 
GAGGATGATC CTACTGTGGA TGACACCAGT GCTGCTGTAA CTGAAGAAAT GCCTCCCCTG 
GAAGGAGATG ACGACACATC ACGCATGGAA GAAGTAGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reduction of cardiac TGFβ-mediated profibrotic events by inhibition of Hsp90 with engineered protein.
Journal of molecular and cellular cardiology12375-87(2018 10)
Cáceres RA,Chavez T,Maestro D,Palanca AR,Bolado P,Madrazo F,Aires A,Cortajarena AL,Villar AV

ZMYND10 functions in a chaperone relay during axonemal dynein assembly.
eLife7(2018 06)
Mali GR,Yeyati PL,Mizuno S,Dodd DO,Tennant PA,Keighren MA,Zur Lage P,Shoemark A,Garcia-Munoz A,Shimada A,Takeda H,Edlich F,Takahashi S,von Kreigsheim A,Jarman AP,Mill P

A switch point in the molecular chaperone Hsp90 responding to client interaction.
Nature communications9(1)1472(2018 04)
Rutz DA,Luo Q,Freiburger L,Madl T,Kaila VRI,Sattler M,Buchner J

Periconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaptation to pregnancy.
Scientific reports8(1)2114(2018 02)
Brown HM,Green ES,Tan TCY,Gonzalez MB,Rumbold AR,Hull ML,Norman RJ,Packer NH,Robertson SA,Thompson JG

Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
The EMBO journal36(24)3650-3665(2017 12)
Woodford MR,Sager RA,Marris E,Dunn DM,Blanden AR,Murphy RL,Rensing N,Shapiro O,Panaretou B,Prodromou C,Loh SN,Gutmann DH,Bourboulia D,Bratslavsky G,Wong M,Mollapour M

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Hsp90aa1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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