Hspa1b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hspa1b
Entrez Gene ID	15511
Full Name	heat shock protein 1B
Synonyms	Hsp70,Hsp70-1,Hsp70.1,hsp68
General protein information	Preferred Names heat shock protein 1B Names heat shock 70 kDa protein 1B 68 kDa heat shock protein heat shock 70 kDa protein 1 heat shock 70kDa protein 1B heat shock protein 70.1 heat shock protein, 70 kDa 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 18.5 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010478.2	NP_034608.2	heat shock 70 kDa protein 1B

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os01g0840100	NP_001044757.1
Oryza sativa (rice)	Os03g0821100	NP_001051724.1
Oryza sativa (rice)	Os11g0703900	NP_001068540.1
Arabidopsis thaliana (thale cress)	HSP70	NP_187864.1
Oryza sativa (rice)	Os03g0276500	NP_001049712.1
Oryza sativa (rice)	Os05g0460000	NP_001055754.1
Canis lupus familiaris (dog)	HSP70	NP_001003067.1
Mus musculus (house mouse)	Hspa1b	NP_034608.2

Gene Ontology
Bibliography

Related articles in PubMed

Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).
Mays CE, Armijo E, Morales R, Kramm C, Flores A, Tiwari A, Bian J, Telling GC, Pandita TK, Hunt CR, Soto C
The Journal of biological chemistry294(37)13619-13628(2019 Sep)

Membrane Hsp70-supported cell-to-cell connections via tunneling nanotubes revealed by live-cell STED nanoscopy.
Reindl J, Shevtsov M, Dollinger G, Stangl S, Multhoff G
Cell stress & chaperones24(1)213-221(2019 01)

Ectromelia virus upregulates the expression of heat shock protein 70 to promote viral replication.
Cheng W, Jia H, Wang X, He X, Jin Q, Cao J, Jing Z
International journal of molecular medicine42(2)1044-1053(2018 Aug)

Mitochondrial proteome disruption in the diabetic heart through targeted epigenetic regulation at the mitochondrial heat shock protein 70 (mtHsp70) nuclear locus.
Shepherd DL, Hathaway QA, Nichols CE, Durr AJ, Pinti MV, Hughes KM, Kunovac A, Stine SM, Hollander JM
Journal of molecular and cellular cardiology119104-115(2018 06)

Downregulation of MiR-199b-5p Inducing Differentiation of Bone-Marrow Mesenchymal Stem Cells (BMSCs) Toward Cardiomyocyte-Like Cells via HSF1/HSP70 Pathway.
Dai F, Du P, Chang Y, Ji E, Xu Y, Wei C, Li J
Medical science monitor : international medical journal of experimental and clinical research242700-2710(2018 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hspa1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hspa1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18851	NM_010478.2 Latest version!	Mus musculus heat shock protein 1B (Hspa1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hspa1b ( NM_010478.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034608.2 Mus musculus heat shock protein 1B (Hspa1b), mRNA.

Price & Availability↑

CloneID	OMu18851
Clone ID Related Accession (Same CDS sequence)	NM_010478.2
Accession Version	NM_010478.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1929bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	heat shock 70 kDa protein 1B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087117.9. On Jan 31, 2007 this sequence version replaced NM_010478.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AK165042.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAGA ACACGGCGAT CGGCATCGAC CTGGGCACCA CCTACTCGTG CGTGGGCGTG 
TTCCAGCACG GCAAGGTGGA GATCATCGCC AACGACCAGG GCAACCGCAC GACCCCCAGC 
TACGTGGCCT TCACCGACAC CGAGCGCCTC ATCGGGGACG CCGCCAAGAA CCAGGTGGCG 
CTGAACCCGC AGAACACCGT GTTCGACGCG AAGCGGCTGA TCGGCCGCAA GTTCGGCGAT 
GCGGTGGTGC AGTCCGACAT GAAGCACTGG CCCTTCCAGG TGGTGAACGA CGGCGACAAG 
CCCAAGGTGC AGGTGAACTA CAAGGGCGAG AGCCGGTCGT TCTTCCCGGA GGAGATCTCG 
TCCATGGTGC TGACGAAGAT GAAGGAGATC GCTGAGGCGT ACCTGGGCCA CCCGGTGACC 
AACGCGGTGA TCACGGTGCC CGCCTACTTC AACGACTCTC AGCGGCAGGC CACCAAGGAC 
GCGGGCGTGA TCGCCGGTCT AAACGTGCTG CGGATCATCA ACGAGCCCAC GGCGGCCGCC 
ATCGCCTACG GGCTGGACCG GACCGGCAAG GGCGAGCGCA ACGTGCTCAT CTTCGACCTG 
GGGGGCGGCA CGTTCGACGT GTCCATCCTG ACGATCGACG ACGGCATCTT CGAGGTGAAG 
GCCACGGCGG GCGACACGCA CCTGGGAGGG GAGGACTTCG ACAACCGGCT GGTGAGCCAC 
TTCGTGGAGG AGTTCAAGAG GAAGCACAAG AAGGACATCA GCCAGAACAA GCGCGCGGTG 
CGGCGGCTGC GCACGGCGTG TGAGAGGGCC AAGAGGACGC TGTCGTCCAG CACCCAGGCC 
AGCCTGGAGA TCGACTCTCT GTTCGAGGGC ATCGACTTCT ACACATCCAT CACGCGGGCG 
CGGTTCGAAG AGCTGTGCTC GGACCTGTTC CGCGGCACGC TGGAGCCCGT GGAGAAGGCC 
CTGCGCGACG CCAAGATGGA CAAGGCGCAG ATCCACGACC TGGTGCTGGT GGGCGGCTCG 
ACGCGCATCC CCAAGGTGCA GAAGCTGCTG CAGGACTTCT TCAACGGGCG CGACCTGAAC 
AAGAGCATCA ACCCGGACGA GGCGGTGGCC TACGGGGCGG CGGTGCAGGC GGCCATCCTG 
ATGGGGGACA AGTCGGAGAA CGTGCAGGAC CTGCTGCTGC TGGACGTGGC GCCGCTGTCG 
CTGGGCCTGG AGACTGCGGG CGGCGTGATG ACGGCGCTCA TCAAGCGCAA CTCCACCATC 
CCCACCAAGC AGACGCAGAC CTTCACCACC TACTCGGACA ACCAGCCCGG GGTGCTGATC 
CAGGTGTACG AGGGCGAGAG GGCCATGACG CGCGACAACA ACCTGCTGGG GCGCTTCGAG 
CTGAGCGGCA TCCCGCCGGC GCCCAGGGGC GTGCCGCAGA TCGAGGTGAC CTTCGACATC 
GACGCCAACG GCATCCTGAA CGTCACGGCC ACCGACAAGA GCACCGGCAA GGCCAACAAG 
ATCACCATCA CCAACGACAA GGGCCGCCTG AGCAAGGAGG AGATCGAGCG CATGGTGCAG 
GAGGCCGAGC GCTACAAGGC CGAGGACGAG GTGCAGCGCG ACAGGGTGGC CGCCAAGAAC 
GCGCTCGAGT CCTATGCCTT CAACATGAAG AGCGCCGTGG AGGACGAGGG TCTCAAGGGC 
AAGCTCAGCG AGGCTGACAA GAAGAAGGTG CTGGACAAGT GCCAGGAGGT CATCTCCTGG 
CTGGACTCCA ACACGCTGGC CGACAAGGAG GAGTTCGTGC ACAAGCGGGA GGAGCTGGAG 
CGGGTGTGCA GCCCCATCAT CAGTGGGCTG TACCAGGGTG CGGGTGCTCC TGGGGCTGGG 
GGCTTCGGGG CCCAGGCGCC GCCGAAAGGA GCCTCTGGCT CAGGACCCAC CATCGAGGAG 
GTGGATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034608.2
CDS	232..2160
Translation	MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPPKGASGSGPTIEEVD

Target ORF information:

RefSeq Version	NM_010478.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus heat shock protein 1B (Hspa1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010478.2

ORF Insert Sequence:

ATGGCCAAGA ACACGGCGAT CGGCATCGAC CTGGGCACCA CCTACTCGTG CGTGGGCGTG 
TTCCAGCACG GCAAGGTGGA GATCATCGCC AACGACCAGG GCAACCGCAC GACCCCCAGC 
TACGTGGCCT TCACCGACAC CGAGCGCCTC ATCGGGGACG CCGCCAAGAA CCAGGTGGCG 
CTGAACCCGC AGAACACCGT GTTCGACGCG AAGCGGCTGA TCGGCCGCAA GTTCGGCGAT 
GCGGTGGTGC AGTCCGACAT GAAGCACTGG CCCTTCCAGG TGGTGAACGA CGGCGACAAG 
CCCAAGGTGC AGGTGAACTA CAAGGGCGAG AGCCGGTCGT TCTTCCCGGA GGAGATCTCG 
TCCATGGTGC TGACGAAGAT GAAGGAGATC GCTGAGGCGT ACCTGGGCCA CCCGGTGACC 
AACGCGGTGA TCACGGTGCC CGCCTACTTC AACGACTCTC AGCGGCAGGC CACCAAGGAC 
GCGGGCGTGA TCGCCGGTCT AAACGTGCTG CGGATCATCA ACGAGCCCAC GGCGGCCGCC 
ATCGCCTACG GGCTGGACCG GACCGGCAAG GGCGAGCGCA ACGTGCTCAT CTTCGACCTG 
GGGGGCGGCA CGTTCGACGT GTCCATCCTG ACGATCGACG ACGGCATCTT CGAGGTGAAG 
GCCACGGCGG GCGACACGCA CCTGGGAGGG GAGGACTTCG ACAACCGGCT GGTGAGCCAC 
TTCGTGGAGG AGTTCAAGAG GAAGCACAAG AAGGACATCA GCCAGAACAA GCGCGCGGTG 
CGGCGGCTGC GCACGGCGTG TGAGAGGGCC AAGAGGACGC TGTCGTCCAG CACCCAGGCC 
AGCCTGGAGA TCGACTCTCT GTTCGAGGGC ATCGACTTCT ACACATCCAT CACGCGGGCG 
CGGTTCGAAG AGCTGTGCTC GGACCTGTTC CGCGGCACGC TGGAGCCCGT GGAGAAGGCC 
CTGCGCGACG CCAAGATGGA CAAGGCGCAG ATCCACGACC TGGTGCTGGT GGGCGGCTCG 
ACGCGCATCC CCAAGGTGCA GAAGCTGCTG CAGGACTTCT TCAACGGGCG CGACCTGAAC 
AAGAGCATCA ACCCGGACGA GGCGGTGGCC TACGGGGCGG CGGTGCAGGC GGCCATCCTG 
ATGGGGGACA AGTCGGAGAA CGTGCAGGAC CTGCTGCTGC TGGACGTGGC GCCGCTGTCG 
CTGGGCCTGG AGACTGCGGG CGGCGTGATG ACGGCGCTCA TCAAGCGCAA CTCCACCATC 
CCCACCAAGC AGACGCAGAC CTTCACCACC TACTCGGACA ACCAGCCCGG GGTGCTGATC 
CAGGTGTACG AGGGCGAGAG GGCCATGACG CGCGACAACA ACCTGCTGGG GCGCTTCGAG 
CTGAGCGGCA TCCCGCCGGC GCCCAGGGGC GTGCCGCAGA TCGAGGTGAC CTTCGACATC 
GACGCCAACG GCATCCTGAA CGTCACGGCC ACCGACAAGA GCACCGGCAA GGCCAACAAG 
ATCACCATCA CCAACGACAA GGGCCGCCTG AGCAAGGAGG AGATCGAGCG CATGGTGCAG 
GAGGCCGAGC GCTACAAGGC CGAGGACGAG GTGCAGCGCG ACAGGGTGGC CGCCAAGAAC 
GCGCTCGAGT CCTATGCCTT CAACATGAAG AGCGCCGTGG AGGACGAGGG TCTCAAGGGC 
AAGCTCAGCG AGGCTGACAA GAAGAAGGTG CTGGACAAGT GCCAGGAGGT CATCTCCTGG 
CTGGACTCCA ACACGCTGGC CGACAAGGAG GAGTTCGTGC ACAAGCGGGA GGAGCTGGAG 
CGGGTGTGCA GCCCCATCAT CAGTGGGCTG TACCAGGGTG CGGGTGCTCC TGGGGCTGGG 
GGCTTCGGGG CCCAGGCGCC GCCGAAAGGA GCCTCTGGCT CAGGACCCAC CATCGAGGAG 
GTGGATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).
The Journal of biological chemistry294(37)13619-13628(2019 Sep)
Mays CE,Armijo E,Morales R,Kramm C,Flores A,Tiwari A,Bian J,Telling GC,Pandita TK,Hunt CR,Soto C

Membrane Hsp70-supported cell-to-cell connections via tunneling nanotubes revealed by live-cell STED nanoscopy.
Cell stress & chaperones24(1)213-221(2019 01)
Reindl J,Shevtsov M,Dollinger G,Stangl S,Multhoff G

Ectromelia virus upregulates the expression of heat shock protein 70 to promote viral replication.
International journal of molecular medicine42(2)1044-1053(2018 Aug)
Cheng W,Jia H,Wang X,He X,Jin Q,Cao J,Jing Z

Mitochondrial proteome disruption in the diabetic heart through targeted epigenetic regulation at the mitochondrial heat shock protein 70 (mtHsp70) nuclear locus.
Journal of molecular and cellular cardiology119104-115(2018 06)
Shepherd DL,Hathaway QA,Nichols CE,Durr AJ,Pinti MV,Hughes KM,Kunovac A,Stine SM,Hollander JM

Downregulation of MiR-199b-5p Inducing Differentiation of Bone-Marrow Mesenchymal Stem Cells (BMSCs) Toward Cardiomyocyte-Like Cells via HSF1/HSP70 Pathway.
Medical science monitor : international medical journal of experimental and clinical research242700-2710(2018 May)
Dai F,Du P,Chang Y,Ji E,Xu Y,Wei C,Li J