Hs3st1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hs3st1
Entrez Gene ID	15476
Full Name	heparan sulfate (glucosamine) 3-O-sulfotransferase 1
Synonyms	3-Ost,D5Wsu110e,Hsg3ost
General protein information	Preferred Names heparan sulfate (glucosamine) 3-O-sulfotransferase 1 Names heparan sulfate glucosamine 3-O-sulfotransferase 1 heparan sulfate 3-O-sulfotransferase 1 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 B3\|5 21.14 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010474.2	NP_034604.1	heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor
XM_017320686.1	XP_017176175.1	heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1
XM_030254167.1	XP_030110027.1	heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1
XM_017320686.2	XP_017176175.1	heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	hs3st1	NP_001011451.1
Macaca mulatta (Rhesus monkey)	HS3ST1	XP_001098326.1
Bos taurus (cattle)	HS3ST1	NP_001069590.1
Rattus norvegicus (Norway rat)	Hs3st1	NP_445843.1
Canis lupus familiaris (dog)	HS3ST1	XP_536238.1
Gallus gallus (chicken)	HS3ST1	XP_420786.1
Homo sapiens (human)	HS3ST1	NP_005105.1
Pan troglodytes (chimpanzee)	HS3ST1	XP_526526.1
Mus musculus (house mouse)	Hs3st1	NP_034604.1
Danio rerio (zebrafish)	hs3st1	NP_001074062.1

Gene Ontology
Bibliography

Related articles in PubMed

HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis.
Smits NC, Kobayashi T, Srivastava PK, Skopelja S, Ivy JA, Elwood DJ, Stan RV, Tsongalis GJ, Sellke FW, Gross PL, Cole MD, DeVries JT, Kaplan AV, Robb JF, Williams SM, Shworak NW
Matrix biology : journal of the International Society for Matrix Biology6369-90(2017 11)

Histochemical analysis of heparan sulfate 3-O-sulfotransferase expression in mouse brain.
Yabe T, Maeda N
Methods in molecular biology (Clifton, N.J.)1229377-87(2015)

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex.
Pereira JD, Sansom SN, Smith J, Dobenecker MW, Tarakhovsky A, Livesey FJ
Proceedings of the National Academy of Sciences of the United States of America107(36)15957-62(2010 Sep)

Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.
Yabe T, Hata T, He J, Maeda N
Glycobiology15(10)982-93(2005 Oct)

A conformational change in heparan sulfate 3-O-sulfotransferase-1 is induced by binding to heparan sulfate.
Edavettal SC, Carrick K, Shah RR, Pedersen LC, Tropsha A, Pope RM, Liu J
Biochemistry43(16)4680-8(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hs3st1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hs3st1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06228	NM_010474.2 Latest version!	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OMu06228	XM_017320686.2 Latest version!	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OMu06228	XM_030254167.1 Latest version!	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
View Old Accession Versions >>
OMu06228	XM_017320686.1	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hs3st1 ( NM_010474.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034604.1 Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), mRNA.

Price & Availability↑

CloneID	OMu06228
Clone ID Related Accession (Same CDS sequence)	NM_010474.2 , XM_017320686.1 , XM_030254167.1 , XM_017320686.2
Accession Version	NM_010474.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568908800000
Organism	Mus musculus(house mouse)
Product	heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ144446.1, AK087753.1 and BY585739.1. On Dec 14, 2007 this sequence version replaced NM_010474.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK087753.1, BC009133.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849389 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034604.1
CDS	322..1257
Translation	MTLLLLGAVLLVAQPQLVHSHPAAPGPGLKQQELLRKVIILPEDTGEGTASNGSTQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSQGLGWYLTQMPFSSPHQLTVEKTPAYFTSPKVPERIHSMNPTIRLLLILRDPSERVLSDYTQVLYNHLQKHKPYPPIEDLLMRDGRLNLDYKALNRSLYHAHMLNWLRFFPLGHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGKDRCLHESKGRAHPQVDPKLLDKLHEYFHEPNKKFFKLVGRTFDWH

Target ORF information:

RefSeq Version	NM_010474.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010474.2

ORF Insert Sequence:

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hs3st1 ( XM_017320686.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017176175.1 Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu06228
Clone ID Related Accession (Same CDS sequence)	NM_010474.2 , XM_017320686.1 , XM_030254167.1 , XM_017320686.2
Accession Version	XM_017320686.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017176175.1
CDS	131..1066
Translation	MTLLLLGAVLLVAQPQLVHSHPAAPGPGLKQQELLRKVIILPEDTGEGTASNGSTQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSQGLGWYLTQMPFSSPHQLTVEKTPAYFTSPKVPERIHSMNPTIRLLLILRDPSERVLSDYTQVLYNHLQKHKPYPPIEDLLMRDGRLNLDYKALNRSLYHAHMLNWLRFFPLGHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGKDRCLHESKGRAHPQVDPKLLDKLHEYFHEPNKKFFKLVGRTFDWH

Target ORF information:

RefSeq Version	XM_017320686.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017320686.1

ORF Insert Sequence:

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hs3st1 ( XM_030254167.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030110027.1 Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu06228
Clone ID Related Accession (Same CDS sequence)	NM_010474.2 , XM_017320686.1 , XM_030254167.1 , XM_017320686.2
Accession Version	XM_030254167.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030110027.1
CDS	553..1488
Translation	MTLLLLGAVLLVAQPQLVHSHPAAPGPGLKQQELLRKVIILPEDTGEGTASNGSTQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSQGLGWYLTQMPFSSPHQLTVEKTPAYFTSPKVPERIHSMNPTIRLLLILRDPSERVLSDYTQVLYNHLQKHKPYPPIEDLLMRDGRLNLDYKALNRSLYHAHMLNWLRFFPLGHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGKDRCLHESKGRAHPQVDPKLLDKLHEYFHEPNKKFFKLVGRTFDWH

Target ORF information:

RefSeq Version	XM_030254167.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030254167.1

ORF Insert Sequence:

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hs3st1 ( XM_017320686.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017176175.1 Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu06228
Clone ID Related Accession (Same CDS sequence)	NM_010474.2 , XM_017320686.1 , XM_030254167.1 , XM_017320686.2
Accession Version	XM_017320686.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	heparan sulfate glucosamine 3-O-sulfotransferase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017320686.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017176175.1
CDS	580..1515
Translation	MTLLLLGAVLLVAQPQLVHSHPAAPGPGLKQQELLRKVIILPEDTGEGTASNGSTQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSQGLGWYLTQMPFSSPHQLTVEKTPAYFTSPKVPERIHSMNPTIRLLLILRDPSERVLSDYTQVLYNHLQKHKPYPPIEDLLMRDGRLNLDYKALNRSLYHAHMLNWLRFFPLGHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGKDRCLHESKGRAHPQVDPKLLDKLHEYFHEPNKKFFKLVGRTFDWH

Target ORF information:

RefSeq Version	XM_017320686.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (Hs3st1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017320686.2

ORF Insert Sequence:

ATGACCTTGC TGCTCCTGGG TGCGGTGCTG CTGGTGGCCC AGCCCCAGCT TGTGCATTCC 
CACCCGGCTG CTCCTGGCCC GGGGCTCAAA CAGCAGGAGC TTCTGAGGAA GGTGATTATT 
CTCCCAGAGG ACACCGGAGA AGGCACAGCA TCCAATGGTT CCACACAGCA GCTGCCACAG 
ACCATCATCA TTGGGGTGCG CAAGGGTGGT ACCCGAGCCC TGCTAGAGAT GCTCAGCCTG 
CATCCTGATG TTGCTGCAGC TGAAAACGAG GTCCATTTCT TTGACTGGGA GGAGCATTAC 
AGCCAAGGCC TGGGCTGGTA CCTCACCCAG ATGCCCTTCT CCTCCCCTCA CCAGCTCACC 
GTGGAGAAGA CACCCGCCTA TTTCACTTCG CCCAAAGTGC CTGAGAGAAT CCACAGCATG 
AACCCCACCA TCCGCCTGCT GCTTATCCTG AGGGACCCAT CAGAGCGCGT GCTGTCCGAC 
TACACCCAGG TGTTGTACAA CCACCTTCAG AAGCACAAGC CCTATCCACC CATTGAGGAC 
CTCCTAATGC GGGACGGTCG GCTGAACCTG GACTACAAGG CTCTCAACCG CAGCCTGTAC 
CATGCACACA TGCTGAACTG GCTGCGTTTT TTCCCGTTGG GCCACATCCA CATTGTGGAT 
GGCGACCGCC TCATCAGAGA CCCTTTCCCT GAGATCCAGA AGGTCGAAAG ATTCCTGAAG 
CTTTCTCCAC AGATCAACGC CTCGAACTTC TACTTTAACA AAACCAAGGG CTTCTACTGC 
CTGCGGGACA GTGGCAAGGA CCGCTGCTTA CACGAGTCCA AAGGCCGGGC GCACCCCCAG 
GTGGATCCCA AACTACTTGA TAAACTGCAC GAATACTTTC ATGAGCCAAA TAAGAAATTT 
TTCAAGCTCG TGGGCAGAAC ATTCGACTGG CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HS3ST1 genotype regulates antithrombin's inflammomodulatory tone and associates with atherosclerosis.
Matrix biology : journal of the International Society for Matrix Biology6369-90(2017 11)
Smits NC,Kobayashi T,Srivastava PK,Skopelja S,Ivy JA,Elwood DJ,Stan RV,Tsongalis GJ,Sellke FW,Gross PL,Cole MD,DeVries JT,Kaplan AV,Robb JF,Williams SM,Shworak NW

Histochemical analysis of heparan sulfate 3-O-sulfotransferase expression in mouse brain.
Methods in molecular biology (Clifton, N.J.)1229377-87(2015)
Yabe T,Maeda N

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex.
Proceedings of the National Academy of Sciences of the United States of America107(36)15957-62(2010 Sep)
Pereira JD,Sansom SN,Smith J,Dobenecker MW,Tarakhovsky A,Livesey FJ

Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.
Glycobiology15(10)982-93(2005 Oct)
Yabe T,Hata T,He J,Maeda N

A conformational change in heparan sulfate 3-O-sulfotransferase-1 is induced by binding to heparan sulfate.
Biochemistry43(16)4680-8(2004 Apr)
Edavettal SC,Carrick K,Shah RR,Pedersen LC,Tropsha A,Pope RM,Liu J

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Hs3st1 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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