H2-Q8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	H2-Q8
Entrez Gene ID	15019
Full Name	histocompatibility 2, Q region locus 8
Synonyms	H-2Q8,MMS10-T,Ms10t,Qa-2,Qa-8,Qa8
General protein information	Preferred Names histocompatibility 2, Q region locus 8 Names H-2 class I histocompatibility antigen, Q8 alpha chain minisatellite 10t detected by probe MMS10
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17

mRNA and Protein(s)

mRNA	Protein	Name
NM_023124.5	NP_075613.3	H-2 class I histocompatibility antigen, Q8 alpha chain precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6.
Ohtsuka M, Inoko H, Kulski JK, Yoshimura S
BMC genomics9178(2008 Apr)

The role of structurally conserved class I MHC in tumor rejection: contribution of the Q8 locus.
Chiang EY, Stroynowski I
Journal of immunology (Baltimore, Md. : 1950)177(4)2123-30(2006 Aug)

Length of uninterrupted repeats determines instability at the unstable mouse expanded simple tandem repeat family MMS10 derived from independent SINE B1 elements.
Bois PR, Southgate L, Jeffreys AJ
Mammalian genome : official journal of the International Mammalian Genome Society12(2)104-11(2001 Feb)

Differential expression of Ped gene candidates in preimplantation mouse embryos.
Wu L, Exley GE, Warner CM
Biology of reproduction59(4)941-52(1998 Oct)

Sequence and transcription of Qa-2-encoding genes in mouse lymphocytes and blastocysts.
Cai W, Cao W, Wu L, Exley GE, Waneck GL, Karger BL, Warner CM
Immunogenetics45(2)97-107(1996)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following H2-Q8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the H2-Q8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00167	NM_023124.5 Latest version!	Mus musculus histocompatibility 2, Q region locus 8 (H2-Q8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

H2-Q8 ( NM_023124.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_075613.3 Mus musculus histocompatibility 2, Q region locus 8 (H2-Q8), mRNA.

Price & Availability↑

CloneID	OMu00167
Clone ID Related Accession (Same CDS sequence)	NM_023124.5
Accession Version	NM_023124.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Mus musculus(house mouse)
Product	H-2 class I histocompatibility antigen, Q8 alpha chain precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U57392.1. On Jun 1, 2012 this sequence version replaced NM_023124.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGCTCTAA CAACGCTGCT CTTGCTGGTG GCGGCCGCCC TGACCCTGAT CGAGACCCGC 
GCGGGCCCAC ACTCGCTGCG GTATTTCCAC ACTGCTGTGT CCTGGCCCGG CCTCGTGGAG 
CCCCGGTTCA TTATCGTCGG CTACGTGGAC GACACGCAGT TCGTGCGCTT CGACAGCGAC 
GCGGAAAATC CGAGGATGGA GCCGCGGGCG CGGTGGATGG AGCAGGAGGG GCCGGAGTAT 
TGGGAGCGGG AGACACAGAA AGCCAAGGGC CATGAGGAGA GTTTCCGAGT GAGCCTGAGG 
ACCGCACAGA GATACTACAA CCAGAGCAAG GGCGGCTCTC ACACACTCCA GTGGATGTAT 
GGCTGTGACG TGGGGTCCGA CGAGCGCCTC CTCCGCGGGT ACCTGCAGTT CGCCTATGAA 
GGCCGCGATT ACATCGCCCT GAACGAAGAC CTGAAAACCT GGACGGCGGC GGACATGGCT 
GCACAGATCA CCCTACACAA GTGGGAGCAG GCTGGTATTG CAGAGAGAGA CCGGGCCTAC 
CTGGAGGGCG CTTGCGTGCA GTCGCTCCGC AGATACCTGC AGCTCCGGAA GGAGACGCTG 
CTGTGCACAG ATCCCCCAAA GGCACATGTG ACCCATCACC CCAGGTCTTA TGGTGCTGTC 
ACCCTGAGGT GCTGGGCCCT GGGCTTCTAC CCTGCTGACA TCACCCTGAC TTGGCAGTTG 
AATGGGGAGG AGCTGACCCA GGACATGGAG CTTGTGGAGA CCAGGCCTGC AGGGGATGGA 
ACCTTCCAGA AGTGGGCATC TGTGGTGGTG CCTCTTGGGA AGGAGCAGAA TTACACATGC 
CATGTGAACC ATGAGGGGCT GCCTGAGCCT CTCACCCTGA GATGGGAGCC TCCTCCATCC 
ACTGTCTCCA ACATGGCGAA CGTAGCTATT CTGGTTGTCC TTGTAGCTTG GCCATCATTG 
GAGCTGTGGT GGATTTTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075613.3
CDS	29..1009
Translation	MALTTLLLLVAAALTLIETRAGPHSLRYFHTAVSWPGLVEPRFIIVGYVDDTQFVRFDSDAENPRMEPRARWMEQEGPEYWERETQKAKGHEESFRVSLRTAQRYYNQSKGGSHTLQWMYGCDVGSDERLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITLHKWEQAGIAERDRAYLEGACVQSLRRYLQLRKETLLCTDPPKAHVTHHPRSYGAVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVNHEGLPEPLTLRWEPPPSTVSNMANVAILVVLVAWPSLELWWIL

Target ORF information:

RefSeq Version	NM_023124.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus histocompatibility 2, Q region locus 8 (H2-Q8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023124.5

ORF Insert Sequence:

ATGGCTCTAA CAACGCTGCT CTTGCTGGTG GCGGCCGCCC TGACCCTGAT CGAGACCCGC 
GCGGGCCCAC ACTCGCTGCG GTATTTCCAC ACTGCTGTGT CCTGGCCCGG CCTCGTGGAG 
CCCCGGTTCA TTATCGTCGG CTACGTGGAC GACACGCAGT TCGTGCGCTT CGACAGCGAC 
GCGGAAAATC CGAGGATGGA GCCGCGGGCG CGGTGGATGG AGCAGGAGGG GCCGGAGTAT 
TGGGAGCGGG AGACACAGAA AGCCAAGGGC CATGAGGAGA GTTTCCGAGT GAGCCTGAGG 
ACCGCACAGA GATACTACAA CCAGAGCAAG GGCGGCTCTC ACACACTCCA GTGGATGTAT 
GGCTGTGACG TGGGGTCCGA CGAGCGCCTC CTCCGCGGGT ACCTGCAGTT CGCCTATGAA 
GGCCGCGATT ACATCGCCCT GAACGAAGAC CTGAAAACCT GGACGGCGGC GGACATGGCT 
GCACAGATCA CCCTACACAA GTGGGAGCAG GCTGGTATTG CAGAGAGAGA CCGGGCCTAC 
CTGGAGGGCG CTTGCGTGCA GTCGCTCCGC AGATACCTGC AGCTCCGGAA GGAGACGCTG 
CTGTGCACAG ATCCCCCAAA GGCACATGTG ACCCATCACC CCAGGTCTTA TGGTGCTGTC 
ACCCTGAGGT GCTGGGCCCT GGGCTTCTAC CCTGCTGACA TCACCCTGAC TTGGCAGTTG 
AATGGGGAGG AGCTGACCCA GGACATGGAG CTTGTGGAGA CCAGGCCTGC AGGGGATGGA 
ACCTTCCAGA AGTGGGCATC TGTGGTGGTG CCTCTTGGGA AGGAGCAGAA TTACACATGC 
CATGTGAACC ATGAGGGGCT GCCTGAGCCT CTCACCCTGA GATGGGAGCC TCCTCCATCC 
ACTGTCTCCA ACATGGCGAA CGTAGCTATT CTGGTTGTCC TTGTAGCTTG GCCATCATTG 
GAGCTGTGGT GGATTTTGTG A